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Pancoast Tumor

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61. Anti-PD-L1 in Stage IIIA(N2) Non-small Cell Lung Cancer (NSCLC)

of the study including undergoing treatment and scheduled visits and examinations including follow-up. Exclusion Criteria: Presence of any distant metastasis or N3 disease. Brain metastases have to be excluded by CT or MRI. Sulcus superior tumors (Pancoast tumors). Previous or concomitant malignancy within 5 years prior registration with the exception of adequately treated localized non-melanoma skin cancer or cervical carcinoma in situ. Any previous treatment for NSCLC. Any previous treatment with a PD-1 (...) , there is a strong rationale to test this novel treatment modality also in the curative setting in order to improve local tumor control and prevent distant metastasis to improve the cure rate in this patient population. The trial investigates the addition of pre- and post-operative immune checkpoint inhibition with MEDI4736 to the previously established standard of care for stage IIIA(N2) patients, which is based on the trials SAKK16/96 and SAKK16/00. Patients whose tumor is deemed resectable at diagnosis

2015 Clinical Trials

62. 电视胸腔镜联合前/后径路在肺上沟瘤切除术中的临床应用 (PubMed)

电视胸腔镜联合前/后径路在肺上沟瘤切除术中的临床应用 The surgical resection for pancoast tumors remains challenging. There are only few reports explaining the use of VATS in the treatment of Pancoast tumors. The aim of this study is to assess whether the use of video-assisted thoracoscopic surgery (VATS) for the surgical treatment of Pancoast tumors was feasible and safe.Between Janunary 2010 and June 2013, ten patients who were diagnosed as Pancoast tumors were (...) of the involved chest wall were done in each patients. The average amount of blood loss was 308 mL and the average time of hospital stay was 14 d. Only one patient had postoperative pneumonia and recovered after use of antibiotics. There was none of severe postoperative complications. No patient developed a local recurrence or distant metastasis within twelve months.The use of VATS has practical value in the management of Pancoast tumors. It is useful to make an accurate extent of the resection of chest-wall

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2015 Chinese Journal of Lung Cancer

63. Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC

carcinomas. Patients with Pancoast tumors adjacent to a vertebral body are eligible as long as all gross disease can be encompassed in the radiation boost field. Pancoast tumor patients will be so-noted in the registry. Patients must be ≥ 18 years of age. Patients with Zubrod (ECOG) performance status ≤ 2. Adequate hematologic function defined as: ANC ≥ 1000/mm3, platelets ≥ 75,000/mm3, and hemoglobin ≥ 8 g/dL (prior to transfusions); adequate hepatic function defined as: total bilirubin ≤ 3.0 mg/dl

2014 Clinical Trials

64. An Outcome Analysis for Stereotactic Body Radiation Therapy (SBRT) Treatment of Non-Small Lung Cancer Patients Using 4D PET/CT With Real-Time Position Management (RPMâ„¢) System and a Concomitant Evaluation of the Impact and Performance Characteristics of

also be excluded. Pancoast tumors would be excluded. Current distant metastatic disease (M1) (preferably biopsy proven). The patient is a female with child-bearing potential who refuses to obtain a serum pregnancy test prior to the initiation of treatment. The patient is pregnant or a female who is nursing an infant. The patient is planning on undergoing systemic therapy within 2 weeks after the last fraction of radiation The patient has an active systemic or pulmonary infection. Contacts (...) Posted : July 18, 2018 Last Update Posted : July 18, 2018 Sponsor: Steven Burton Information provided by (Responsible Party): Steven Burton, University of Pittsburgh Study Details Study Description Go to Brief Summary: The goals of this clinical research are to evaluate the outcomes and tumor response for early stage non-small lung cancer (NSCLC) patients undergoing Stereotactic Body Radiation Therapy (SBRT) using four dimensional (4D) Positron Emission Tomography (PET) and Computed Tomography (CT

2014 Clinical Trials

65. Non-Small Cell Lung Cancer

. Asbestos exposure may exert a synergistic effect of cigarette smoking on the lung cancer risk.[ ] Prevention A significant number of patients cured of their smoking-related lung cancer may develop a second malignancy. In the Lung Cancer Study Group trial of 907 patients with stage T1, N0 resected tumors, the rate was 1.8% per year for nonpulmonary second cancers and 1.6% per year for new lung cancers.[ ] Other studies have reported even higher risks of second tumors in long-term survivors, including (...) pathologist must review the pathologic material. This is critical because SCLC, which responds well to chemotherapy and is generally not treated surgically, can be confused on microscopic examination with NSCLC.[ ] Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but most lung tumors can be classified by light microscopic criteria. (Refer to the section of this summary for more information on tests and procedures used for staging.) Molecular

2012 PDQ - NCI's Comprehensive Cancer Database

66. Horner Syndrome (Diagnosis)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

67. Horner Syndrome (Treatment)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

68. The Approach to the Painful Joint (Treatment)

polyarthritis include the following: Traumatic osteoarthritis (see ) Hypertrophic pulmonary osteoarthropathy Amyloidosis (see ) Differential diagnoses for regional musculoskeletal pain Shoulder Referred pain may derive from cervical disorders, Pancoast tumor of the lung, subphrenic pathology, or entrapment neuropathies and brachial neuritis (see ). Rotator cuff tendinitis (see ) [ ] is inflammation of the rotator cuff tendons, arising acutely as a result of a recognizable injury (throwing) or insidiously (...) Trauma Hemarthrosis Osteonecrosis Inflammatory processes associated with chronic monoarthritis include the following: Chronic infectious arthritis (see ) Crystalline synovitis (see ) Pauciarticular juvenile idiopathic arthritis (RA; see ) Systemic rheumatic disease presenting with monoarticular involvement Noninflammatory processes associated with chronic monoarthritis include the following: Ischemic necrosis (see ) Hemarthrosis Paget disease involving the joint (see ) Metastatic tumor Synovial

2014 eMedicine.com

69. Reflex Sympathetic Dystrophy (Overview)

Dental extractions Cervical rib resection Fracture repair (Colles fracture) Arthroscopy Local disorders associated with CRPS 1 include the following: Nerve compression syndromes Arthritis Tissue ischemia Stenosing tenosynovitis Systemic disorders associated with CRPS 1 include the following: Myocardial infarction Stroke Pancoast tumor Pancreatic cancer Herpes zoster Previous Next: Epidemiology Frequency In the United States, an estimated 5% of patients who experience trauma to the upper extremity

2014 eMedicine.com

70. The Approach to the Painful Joint (Overview)

polyarthritis include the following: Traumatic osteoarthritis (see ) Hypertrophic pulmonary osteoarthropathy Amyloidosis (see ) Differential diagnoses for regional musculoskeletal pain Shoulder Referred pain may derive from cervical disorders, Pancoast tumor of the lung, subphrenic pathology, or entrapment neuropathies and brachial neuritis (see ). Rotator cuff tendinitis (see ) [ ] is inflammation of the rotator cuff tendons, arising acutely as a result of a recognizable injury (throwing) or insidiously (...) Trauma Hemarthrosis Osteonecrosis Inflammatory processes associated with chronic monoarthritis include the following: Chronic infectious arthritis (see ) Crystalline synovitis (see ) Pauciarticular juvenile idiopathic arthritis (RA; see ) Systemic rheumatic disease presenting with monoarticular involvement Noninflammatory processes associated with chronic monoarthritis include the following: Ischemic necrosis (see ) Hemarthrosis Paget disease involving the joint (see ) Metastatic tumor Synovial

2014 eMedicine.com

71. Horner Syndrome (Overview)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

72. Horner Syndrome (Overview)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

73. The Approach to the Painful Joint (Follow-up)

polyarthritis include the following: Traumatic osteoarthritis (see ) Hypertrophic pulmonary osteoarthropathy Amyloidosis (see ) Differential diagnoses for regional musculoskeletal pain Shoulder Referred pain may derive from cervical disorders, Pancoast tumor of the lung, subphrenic pathology, or entrapment neuropathies and brachial neuritis (see ). Rotator cuff tendinitis (see ) [ ] is inflammation of the rotator cuff tendons, arising acutely as a result of a recognizable injury (throwing) or insidiously (...) Trauma Hemarthrosis Osteonecrosis Inflammatory processes associated with chronic monoarthritis include the following: Chronic infectious arthritis (see ) Crystalline synovitis (see ) Pauciarticular juvenile idiopathic arthritis (RA; see ) Systemic rheumatic disease presenting with monoarticular involvement Noninflammatory processes associated with chronic monoarthritis include the following: Ischemic necrosis (see ) Hemarthrosis Paget disease involving the joint (see ) Metastatic tumor Synovial

2014 eMedicine.com

74. Horner Syndrome (Follow-up)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

75. Horner Syndrome (Follow-up)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

76. Horner Syndrome (Diagnosis)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

77. Carpal Tunnel Syndrome

. These include multiple sclerosis, cervical radiculopathy, Pancoast tumor, brachial plexitis or brachial plexopathy, pronator syndrome, ulnar or radial neuropathy, generalized neuropathy, and median nerve contusion. Although the appearance of carpal tunnel syndrome is fairly distinctive on MRI, differential possibilities include contusion and lipofibromatous hamartoma of the median nerve. A clinical history of recent trauma or a longstanding mass often allows the exclusion or inclusion of these etiologies

2014 eMedicine Radiology

78. Reflex Sympathetic Dystrophy (Diagnosis)

Dental extractions Cervical rib resection Fracture repair (Colles fracture) Arthroscopy Local disorders associated with CRPS 1 include the following: Nerve compression syndromes Arthritis Tissue ischemia Stenosing tenosynovitis Systemic disorders associated with CRPS 1 include the following: Myocardial infarction Stroke Pancoast tumor Pancreatic cancer Herpes zoster Previous Next: Epidemiology Frequency In the United States, an estimated 5% of patients who experience trauma to the upper extremity

2014 eMedicine.com

79. The Approach to the Painful Joint (Diagnosis)

polyarthritis include the following: Traumatic osteoarthritis (see ) Hypertrophic pulmonary osteoarthropathy Amyloidosis (see ) Differential diagnoses for regional musculoskeletal pain Shoulder Referred pain may derive from cervical disorders, Pancoast tumor of the lung, subphrenic pathology, or entrapment neuropathies and brachial neuritis (see ). Rotator cuff tendinitis (see ) [ ] is inflammation of the rotator cuff tendons, arising acutely as a result of a recognizable injury (throwing) or insidiously (...) Trauma Hemarthrosis Osteonecrosis Inflammatory processes associated with chronic monoarthritis include the following: Chronic infectious arthritis (see ) Crystalline synovitis (see ) Pauciarticular juvenile idiopathic arthritis (RA; see ) Systemic rheumatic disease presenting with monoarticular involvement Noninflammatory processes associated with chronic monoarthritis include the following: Ischemic necrosis (see ) Hemarthrosis Paget disease involving the joint (see ) Metastatic tumor Synovial

2014 eMedicine.com

80. Horner Syndrome (Treatment)

that may give rise to Horner syndrome include the following: Pancoast tumor (tumor in the apex of the lung, most commonly squamous cell carcinoma) Birth trauma with injury to lower brachial plexus [ ] Cervical rib Aneurysm or dissection of the aorta Lesions of the subclavian or common carotid artery Central venous catheterization Trauma or surgical injury (eg, due to radical neck dissection, thyroidectomy, [ ] carotid angiography, radiofrequency tonsil ablation, [ ] chiropractic manipulation (...) in the presence of axial, shoulder, scapula, arm, or hand pain may be indicative of compression by an apical lung tumor (Pancoast tumor). Horner syndrome in the presence of acute-onset, ipsilateral facial or neck pain may indicate carotid artery dissection, which may be caused by cardiovascular disease, arteriopathy (eg, fibromuscular dysplasia or collagen disorders), or trauma (even minor trauma, such as results from quick head turns). If carotid artery dissection is suspected, especially if there are signs

2014 eMedicine.com

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