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Pancoast Tumor

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21. Pancoast Tumor: The Role of Magnetic Resonance Imaging Full Text available with Trip Pro

Pancoast Tumor: The Role of Magnetic Resonance Imaging We report imaging techniques in the definition of the therapeutic planning of a 65-year-old man with a diagnosis of Pancoast tumor. Computed Tomography has a pivotal role in the assessment of nodes involvement and distant metastasis. Magnetic Resonance allows a detailed study of locoregional extension for its high soft tissue resolution. We particularly highlight the actual importance of Magnetic Resonance Neurography, Diffusion-Weighted

2013 Case Reports in Radiology

22. Pancoast Tumor

Database) Ontology: Pancoast Tumor (C0549471) Definition (MSH) A lung tumor located in the superior pulmonary sulcus. Definition (NCI_NCI-GLOSS) A type of lung cancer that begins in the upper part of a lung and spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non-small cell cancers. Definition (NCI) A malignant neoplasm originating from the apical lung. Most malignant superior sulcus neoplasms are bronchogenic carcinomas. This tumor may be associated with Pancoast (...) , superior sulcus tumor , Pancoast tumor , Pancoast tumour , Superior sulcus tumor , Superior sulcus tumour , Pancoast tumor (disorder) , Pancoast; tumor , tumor; Pancoast , Malignant Superior Sulcus Lung Neoplasm , Malignant Superior Sulcus Lung Tumor , Malignant Superior Sulcus Neoplasm of Lung , Malignant Superior Sulcus Neoplasm of the Lung , Malignant Superior Sulcus Neoplasm , Malignant Superior Sulcus Tumor of Lung , Malignant Superior Sulcus Tumor of the Lung , Malignant Superior Sulcus Tumor

2015 FP Notebook

23. Hepatoid Pancoast tumor. A case report and review of the literature. (Abstract)

Hepatoid Pancoast tumor. A case report and review of the literature. A 48-year-old male patient presented with a Pancoast tumor of the right lung and a serum alpha-fetoprotein (αFP) at 39,000 ng/ml. Alpha-fetoprotein is a tumor marker found elevated in patients with hepatocellular carcinoma (HCC), germ cell or stromal tumors of the ovary and nonseminomatous testicular cancer. Occasionally, this tumor marker may rise in non-neoplastic conditions such as cirrhosis and hepatitis and only (...) exceptionally in rare cancers with hepatoid differentiation. We present our case report and review the English literature for αFP-producing lung carcinomas. To the best of our knowledge this is the first report in the literature of an αFP producing Pancoast tumor.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

2012 Lung Cancer

24. Non-Invasive Clinical Staging of Bronchogenic Carcinoma

of caring for lung cancer patients in the United States is over $12 billion per year. Mortality cost from lost productivity also numbers in the billions of dollars [2]. Non–small-cell lung cancer (NSCLC), including adenocarcinoma, squamous-cell carcinoma, and large-cell carcinoma, comprises about 85% of lung cancers. SCLC accounts for approximately 13% to 15% of cases. Prognosis is directly related to stage at presentation, with 5-year survival ranging as high as 77% for small stage IA cancers to 1 (...) % to 2% for stage IV lung cancer [3]. The majority of lung cancer patients present with advanced disease. Selection of appropriate treatment options including curative surgery, radiation therapy, chemotherapy, targeted therapy, or multimodality therapy is increasingly influenced by pathologic evaluation with immunohistochemical staining but remains dependent on accurate staging. Discussion of Procedures by Variant Variant 1: Noninvasive initial clinical staging of non–small-cell lung carcinoma. NSCLC

2013 American College of Radiology

25. An effective and safe surgical approach for a superior sulcus tumor: A case report Full Text available with Trip Pro

An effective and safe surgical approach for a superior sulcus tumor: A case report Superior sulcus tumors, frequently referred to as Pancoast tumors, are a wide range of tumors invading a section of the apical chest wall called the thoracic inlet. For this reason, a surgical approach and complete resection may be difficult to accomplish. We experienced a locally advanced superior sulcus tumor (SST) located from the anterior to posterior apex thoracic inlet and performed complete resection after (...) definitive chemoradiation.A 71-year-old Japanese male presented at our hospital due to left back pain and an abnormal chest computed tomography (CT) scan showing 80×70×60-mm tumor located in the left middle apex thoracic inlet. This tumor was located near the subclavian artery, and the subclavian lymph nodes were swollen. The tumor was found to be an adenocarcinoma (clinical-T3N3M0 stage IIIB). Therefore, we performed definitive chemoradiation therapy. Slight reduction in the tumor size was noted after

2017 International journal of surgery case reports

26. Point: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? Yes. (Abstract)

Point: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? Yes. 26110373 2016 04 27 2017 06 19 1931-3543 148 6 2015 Dec Chest Chest POINT: Is N2 Disease a Contraindication for Surgical Resection for Superior Sulcus Tumors? Yes. 1373-1375 S0012-3692(15)50097-4 10.1378/chest.15-1194 Tanner Nichole T NT Ralph H. Johnson Veterans Affairs Hospital, Health Equity and Rural Outreach Innovation Center, Charleston, SC; Division of Pulmonary and Critical Care, Allergy (...) and Sleep Medicine, Medical University of South Carolina, Charleston, SC. Electronic address: tripici@musc.edu. Silvestri Gerard A GA Division of Pulmonary and Critical Care, Allergy and Sleep Medicine, Medical University of South Carolina, Charleston, SC. eng Editorial United States Chest 0231335 0012-3692 AIM IM Chest. 2015 Dec;148(6):1380-1 26110719 Antineoplastic Combined Chemotherapy Protocols therapeutic use Carcinoma, Non-Small-Cell Lung diagnosis surgery Humans Neoplasm Staging Outcome

2015 Chest

27. Counterpoint: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? No. (Abstract)

Counterpoint: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? No. 26110487 2016 04 27 2017 06 19 1931-3543 148 6 2015 Dec Chest Chest COUNTERPOINT: Is N2 Disease a Contraindication for Surgical Resection for Superior Sulcus Tumors? No. 1375-1379 S0012-3692(15)50098-6 10.1378/chest.15-1196 Li Wilson W WW Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: w.w.li@amc.uva.nl (...) . Burgers Jacobus A JA Department of Thoracic Oncology, Amsterdam, The Netherlands. Klomp Houke M HM Department of Thoracic Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. Hartemink Koen J KJ Department of Thoracic Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. eng Editorial United States Chest 0231335 0012-3692 AIM IM Chest. 2015 Dec;148(6):1379-80 26110565 Carcinoma, Non-Small-Cell Lung diagnosis

2015 Chest

28. Pancoast Syndrome (Diagnosis)

, 2017 Author: Karl J D'Silva, MD; Chief Editor: Nagla Abdel Karim, MD, PhD Share Email Print Feedback Close Sections Sections Pancoast Syndrome Overview Practice Essentials Pancoast syndrome (Pancoast’s syndrome) typically results when a malignant neoplasm of the superior sulcus of the lung (lung cancer) leads to destructive lesions of the thoracic inlet and involvement of the brachial plexus and cervical sympathetic nerves (stellate ganglion). [ , , ] This is accompanied by the following: Severe (...) pain in the shoulder region radiating toward the axilla and scapula, with later extension along the ulnar aspect of the arm to the hand Atrophy of hand and arm muscles ( , miosis, hemianhidrosis, ) Compression of the blood vessels with edema Most Pancoast tumors are (SCCs) or adenocarcinomas; only 3-5% are small cell carcinomas. Squamous cell carcinoma occurs more frequently, although large cell and undifferentiated types are also common. Adenocarcinoma is sometimes found in this location and can

2014 eMedicine.com

29. Pancoast Syndrome (Treatment)

be curable. However, extrapolation from the data for non-Pancoast stage III non–small-cell lung cancer (NSCLC) suggests that chemoradiotherapy is the best approach. In patients whose disease is believed incurable, radiotherapy offers good palliation of pain. Ultrasound-guided cervical nerve roots ablation can be considered for patients with intractable neuropathic pain secondary to Pancoast tumor. Anecdotal reports have described excellent pain relief as well as improvement in quality of sleep (...) Gaz . 1838. 1:16-18. Glassman LR, Hyman K. Pancoast tumor: a modern perspective on an old problem. Curr Opin Pulm Med . 2013 Jul. 19 (4):340-3. . Paulson DL. Carcinomas in the superior pulmonary sulcus. J Thorac Cardiovasc Surg . 1975 Dec. 70(6):1095-104. . Pitz CC, de la Rivière AB, van Swieten HA, Duurkens VA, Lammers JW, van den Bosch JM. Surgical treatment of Pancoast tumours. Eur J Cardiothorac Surg . 2004 Jul. 26(1):202-8. . Maggi G, Casadio C, Pischedda F, et al. Combined radiosurgical

2014 eMedicine.com

30. Pancoast Syndrome (Overview)

, 2017 Author: Karl J D'Silva, MD; Chief Editor: Nagla Abdel Karim, MD, PhD Share Email Print Feedback Close Sections Sections Pancoast Syndrome Overview Practice Essentials Pancoast syndrome (Pancoast’s syndrome) typically results when a malignant neoplasm of the superior sulcus of the lung (lung cancer) leads to destructive lesions of the thoracic inlet and involvement of the brachial plexus and cervical sympathetic nerves (stellate ganglion). [ , , ] This is accompanied by the following: Severe (...) pain in the shoulder region radiating toward the axilla and scapula, with later extension along the ulnar aspect of the arm to the hand Atrophy of hand and arm muscles ( , miosis, hemianhidrosis, ) Compression of the blood vessels with edema Most Pancoast tumors are (SCCs) or adenocarcinomas; only 3-5% are small cell carcinomas. Squamous cell carcinoma occurs more frequently, although large cell and undifferentiated types are also common. Adenocarcinoma is sometimes found in this location and can

2014 eMedicine.com

31. Pancoast Syndrome (Follow-up)

be curable. However, extrapolation from the data for non-Pancoast stage III non–small-cell lung cancer (NSCLC) suggests that chemoradiotherapy is the best approach. In patients whose disease is believed incurable, radiotherapy offers good palliation of pain. Ultrasound-guided cervical nerve roots ablation can be considered for patients with intractable neuropathic pain secondary to Pancoast tumor. Anecdotal reports have described excellent pain relief as well as improvement in quality of sleep (...) Gaz . 1838. 1:16-18. Glassman LR, Hyman K. Pancoast tumor: a modern perspective on an old problem. Curr Opin Pulm Med . 2013 Jul. 19 (4):340-3. . Paulson DL. Carcinomas in the superior pulmonary sulcus. J Thorac Cardiovasc Surg . 1975 Dec. 70(6):1095-104. . Pitz CC, de la Rivière AB, van Swieten HA, Duurkens VA, Lammers JW, van den Bosch JM. Surgical treatment of Pancoast tumours. Eur J Cardiothorac Surg . 2004 Jul. 26(1):202-8. . Maggi G, Casadio C, Pischedda F, et al. Combined radiosurgical

2014 eMedicine.com

32. Superior Sulcus Tumour Full Text available with Trip Pro

Superior Sulcus Tumour 13190215 2003 05 01 2018 12 01 0007-1447 2 4888 1954 Sep 11 British medical journal Br Med J Superior sulcus tumour. 631 YOUNG R D RD eng Journal Article England Br Med J 0372673 0007-1447 OM Carcinoma Carcinoma, Squamous Cell Humans Lung Neoplasms Pancoast Syndrome 5527:1795:94:274 CARCINOMA, EPIDERMOID LUNGS/neoplasms 1954 9 11 1954 9 11 0 1 1954 9 11 0 0 ppublish 13190215 PMC2078960 J Thorac Surg. 1953 Apr;25(4):402-12 13035882 J Am Med Assoc. 1954 Jan 23;154(4):323-6

1954 British medical journal

33. Diagnosis of a thoracic inlet tumour by transbronchial biopsy. Full Text available with Trip Pro

Diagnosis of a thoracic inlet tumour by transbronchial biopsy. A 67-year-old man presented to the pulmonary service with left shoulder and arm pain. Examination disclosed a left Horner's syndrome. Supraclavicular exploration at another hospital was not helpful. Transbronchial biopsy through a flexible fibreoptic bronchoscope retrieved tissues showing poorly differentiated carcinoma. There are no previous reports of the use of the technique in the diagnosis of a Pancoast tumour with a normal

1978 Thorax

34. Patient Navigation Models for Lung Cancer

care. Patient navigation began in the United States in 1990 with a surgical oncologist, Harold Freeman, who wanted to address the disparities in breast cancer outcomes among African American women in Harlem. 5 The primary aims of patient navigation are to eliminate financial, logistic, or communication barriers to the receipt of medical services by providing education and resources to patients. 6 In 2005 the Patient Navigator and Chronic Disease Prevention Act was signed into law which authorized (...) , 28 for breast cancer services but has been adopted to other oncological and chronic disease services in the BMC. The patients in the patient navigation group demonstrated higher mammogram adherence than in the control group (p < 0.001), 28 and were more likely to follow-up within 120 days of the initial appointment (39% greater odds, 95% confidence interval, 1.01–1.9). 27 This toolkit, using evidence- and experience-based examples, aims to help other health care systems develop patient navigation

2018 Effective Health Care Program (AHRQ)

35. Myeloma presenting with Pancoast's syndrome. Full Text available with Trip Pro

Myeloma presenting with Pancoast's syndrome. 760938 1979 04 28 2018 11 13 0007-1447 1 6155 1979 Jan 06 British medical journal Br Med J Myeloma presenting with Pancoast's syndrome. 20 Wilson K S KS Cunningham T A TA Alexander S S eng Case Reports Journal Article England Br Med J 0372673 0007-1447 AIM IM Aged Humans Male Multiple Myeloma complications Neoplasm Metastasis Pancoast Syndrome etiology Shoulder physiopathology 1979 1 6 1979 1 6 0 1 1979 1 6 0 0 ppublish 760938 PMC1597490 Medicine

1979 British medical journal

36. Diagnosis, staging and treatment of patients with Lung Cancer

on the nature of the pleural fluid, pleural biopsy using image guided or thoracoscopic biopsy is recommended. (D) 2.3.4.1 In lung cancer patients with symptomatic (including breathlessness, haemoptysis and cough) malignant airway obstruction, any of the following therapeutic interventions may be considered: bronchoscopic debulking, tumour ablation modalities, airway stent placement and radiotherapy (external beam or brachytherapy). (D) 2.3.5 Staging algorithm for patients with suspected lung cancer (Figure (...) categories of patients with lung cancer, the reliability of CT in the assessment of mediastinal nodes is poor with average false positive and negative rates of 45% and 13% respectively (Detterbeck et al., 2001a). The false negative rate is higher with central tumours and adenocarcinomas (22% and 19%). (SIGN, 2014) PET scanning of mediastinal nodes (N2/3) 18F-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography (FDG PET-CT) is more accurate than CT in detecting mediastinal nodal

2017 Health Service Executive (Ireland) - Clinical Guidelines

37. Diagnosis, staging and treatment of patients with lung cancer

on the nature of the pleural fluid, pleural biopsy using image guided or thoracoscopic biopsy is recommended. (D) 2.3.4.1 In lung cancer patients with symptomatic (including breathlessness, haemoptysis and cough) malignant airway obstruction, any of the following therapeutic interventions may be considered: bronchoscopic debulking, tumour ablation modalities, airway stent placement and radiotherapy (external beam or brachytherapy). (D) 2.3.5 Staging algorithm for patients with suspected lung cancer (Figure (...) categories of patients with lung cancer, the reliability of CT in the assessment of mediastinal nodes is poor with average false positive and negative rates of 45% and 13% respectively (Detterbeck et al., 2001a). The false negative rate is higher with central tumours and adenocarcinomas (22% and 19%). (SIGN, 2014) PET scanning of mediastinal nodes (N2/3) 18F-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography (FDG PET-CT) is more accurate than CT in detecting mediastinal nodal

2017 National Clinical Guidelines (Ireland)

38. Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm.

Cancer Institute Investigators Layout table for investigator information Principal Investigator: Heike Peulen, MD The Netherlands Cancer Institute More Information Go to Layout table for additonal information Responsible Party: The Netherlands Cancer Institute ClinicalTrials.gov Identifier: Other Study ID Numbers: N12HYB First Posted: September 2, 2013 Last Update Posted: March 13, 2018 Last Verified: March 2018 Additional relevant MeSH terms: Layout table for MeSH terms Lung Neoplasms Carcinoma, Non (...) -Small-Cell Lung Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases Carcinoma, Bronchogenic Bronchial Neoplasms Cisplatin Antineoplastic Agents

2013 Clinical Trials

39. [Analysis of preoperative concurrent chemoradiotherapy in the treatment of patients with superior sulcus tumor of the lung]. (Abstract)

[Analysis of preoperative concurrent chemoradiotherapy in the treatment of patients with superior sulcus tumor of the lung]. Recently chemoradiotherapy becomes a standard treatment for un- resectable advanced non-small cell lung cancer (NSCLC) instead of radiotherapy alone. Superior sulcus tumor of the lung (Pancoast tumor) is a clinical subtype of NSCLC. The aim of this study is to compare the clinical effects and toxicities of preoperative concurrent chemoradiotherapy with radiotherapy alone (...) in patients with superior sulcus tumors.Fifty-six patients with superior sulcus tumors were divided randomly into two groups: twenty-six patients received concurrent chemoradiotherapy (chemoradiotherapy group), the other thirty patients received only radiotherapy (radiotherapy group). For both groups, the same radiation technic was given with the convention fraction. The total dose was 45Gy/25 fraction/5 weeks. For the chemoradiotherapy group, the patients were also given with concurrent chemotherapy

2012 Zhongguo fei ai za zhi = Chinese journal of lung cancer Controlled trial quality: uncertain

40. Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously

by (Responsible Party): The Netherlands Cancer Institute Study Details Study Description Go to Brief Summary: Treatment of larger tumor volumes or ≥ 2 lung metastases simultaneously in lung cancer patient using Stereotactic Body Radiation Therapy (SBRT) in a mean-lung dose escalation study. Condition or disease Intervention/treatment Phase Lung Cancer Metastatic Lung Cancer Radiation: Stereotactic Body Radiotherapy (SBRT) Phase 1 Phase 2 Detailed Description: A phase I/II multicenter trial will be conducted (...) of a history of an already proven disseminated disease. Patients having ≥ 2 peripheral lung metastases without unacceptable dose overlap. Exclusion Criteria: Patients with central tumors Pancoast tumors Prior radiotherapy treatment to the thorax Patients receiving any systemic treatment during SBRT Pregnant patients Patients previously treated with adriamycin agents in case of heart involvement within the treatment field. Contacts and Locations Go to Information from the National Library of Medicine

2012 Clinical Trials

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