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Pancoast Tumor

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21. Squamous Cell Carcinoma on the Remaining Sequel of Tuberculosis, Presented as Pancoast Tumor 8 Years Later (PubMed)

Squamous Cell Carcinoma on the Remaining Sequel of Tuberculosis, Presented as Pancoast Tumor 8 Years Later Herein a 46 year-old man is presented with intolerable severe pain of right shoulder radiating to right arm and fourth and fifth fingers. He had a history of right upper lobectomy due to complicated tuberculosis eight years ago. Based on the findings of clinical examination and computed tomography imaging, diagnosis of Pancoast tumor of the right chest apex was confirmed. However, Fine (...) Needle Aspiration (FNA) under computed tomography (CT) guidance was not conclusive. By performing a limited thoracotomy, multiple biopsy specimens were obtained from the mass and destroyed ribs for histopathologic examination which consequently confirmed the diagnosis of squamous cell carcinoma. Eventually, the patient was referred to the radiotherapy ward for treatment of Pancoast tumor.

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2012 Tanaffos

22. Pancoast Tumor

Pancoast Tumor Pancoast Tumor Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pancoast Tumor Pancoast Tumor Aka: Pancoast Tumor From (...) Related Chapters II. Definition Apical Tumor of superior sulcus lung III. Course Superior sulcus marked by subclavian artery Grows into thoracic outlet IV. Signs Supraclavicular fullness Venous distension Upper extremity edema and muscle wasting (C8-T3) Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Pancoast Tumor." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip

2015 FP Notebook

23. Pancoast Syndrome (Treatment)

=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjg0MDExLXRyZWF0bWVudA== processing > Pancoast Syndrome Treatment & Management Updated: Nov 14, 2017 Author: Karl J D'Silva, MD; Chief Editor: Nagla Abdel Karim, MD, PhD Share Email Print Feedback Close Sections Sections Pancoast Syndrome Treatment Approach Considerations Pancoast tumors were once considered universally fatal. However, improvements in combined modality therapy and the development of new techniques for resection have made curative treatment possible for these tumors. [ , ] For example, in 1993 (...) be curable. However, extrapolation from the data for non-Pancoast stage III non–small-cell lung cancer (NSCLC) suggests that chemoradiotherapy is the best approach. In patients whose disease is believed incurable, radiotherapy offers good palliation of pain. Ultrasound-guided cervical nerve roots ablation can be considered for patients with intractable neuropathic pain secondary to Pancoast tumor. Anecdotal reports have described excellent pain relief as well as improvement in quality of sleep

2014 eMedicine.com

24. Pancoast Syndrome (Overview)

pain in the shoulder region radiating toward the axilla and scapula, with later extension along the ulnar aspect of the arm to the hand Atrophy of hand and arm muscles ( , miosis, hemianhidrosis, ) Compression of the blood vessels with edema Most Pancoast tumors are (SCCs) or adenocarcinomas; only 3-5% are small cell carcinomas. Squamous cell carcinoma occurs more frequently, although large cell and undifferentiated types are also common. Adenocarcinoma is sometimes found in this location and can (...) even be metastatic. Involvement of the phrenic or recurrent laryngeal nerve or superior vena cava obstruction is not representative of the classic Pancoast tumor. Once universally fatal, Pancoast tumors are currently treatable with outcomes similar to those of other stage-matched non–small cell lung cancers. [ ] Careful assessment and appropriate staging are performed before surgery, and selected patients are administered preoperative irradiation of 30 Gy over 2 weeks. After an interval of 2-4

2014 eMedicine.com

25. Pancoast Syndrome (Follow-up)

=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjg0MDExLXRyZWF0bWVudA== processing > Pancoast Syndrome Treatment & Management Updated: Nov 14, 2017 Author: Karl J D'Silva, MD; Chief Editor: Nagla Abdel Karim, MD, PhD Share Email Print Feedback Close Sections Sections Pancoast Syndrome Treatment Approach Considerations Pancoast tumors were once considered universally fatal. However, improvements in combined modality therapy and the development of new techniques for resection have made curative treatment possible for these tumors. [ , ] For example, in 1993 (...) be curable. However, extrapolation from the data for non-Pancoast stage III non–small-cell lung cancer (NSCLC) suggests that chemoradiotherapy is the best approach. In patients whose disease is believed incurable, radiotherapy offers good palliation of pain. Ultrasound-guided cervical nerve roots ablation can be considered for patients with intractable neuropathic pain secondary to Pancoast tumor. Anecdotal reports have described excellent pain relief as well as improvement in quality of sleep

2014 eMedicine.com

26. Pancoast Syndrome (Diagnosis)

pain in the shoulder region radiating toward the axilla and scapula, with later extension along the ulnar aspect of the arm to the hand Atrophy of hand and arm muscles ( , miosis, hemianhidrosis, ) Compression of the blood vessels with edema Most Pancoast tumors are (SCCs) or adenocarcinomas; only 3-5% are small cell carcinomas. Squamous cell carcinoma occurs more frequently, although large cell and undifferentiated types are also common. Adenocarcinoma is sometimes found in this location and can (...) even be metastatic. Involvement of the phrenic or recurrent laryngeal nerve or superior vena cava obstruction is not representative of the classic Pancoast tumor. Once universally fatal, Pancoast tumors are currently treatable with outcomes similar to those of other stage-matched non–small cell lung cancers. [ ] Careful assessment and appropriate staging are performed before surgery, and selected patients are administered preoperative irradiation of 30 Gy over 2 weeks. After an interval of 2-4

2014 eMedicine.com

27. En bloc resection of 3 vertebra in a pancoast patient: long-term stability using a free vascularized fibular graft. (PubMed)

En bloc resection of 3 vertebra in a pancoast patient: long-term stability using a free vascularized fibular graft. Vertebral involvement is no longer a contraindication for resection in superior sulcus tumors. We describe the reconstruction of thoracic vertebras 2 to 4 using a free vascularized fibular graft combined with dorsal and ventral stabilization using rods, screws, and hooks after resection of a superior sulcus tumor that invaded the thoracic spine. No complications have occurred

2011 Annals of Thoracic Surgery

28. An effective and safe surgical approach for a superior sulcus tumor: A case report (PubMed)

An effective and safe surgical approach for a superior sulcus tumor: A case report Superior sulcus tumors, frequently referred to as Pancoast tumors, are a wide range of tumors invading a section of the apical chest wall called the thoracic inlet. For this reason, a surgical approach and complete resection may be difficult to accomplish. We experienced a locally advanced superior sulcus tumor (SST) located from the anterior to posterior apex thoracic inlet and performed complete resection after (...) definitive chemoradiation.A 71-year-old Japanese male presented at our hospital due to left back pain and an abnormal chest computed tomography (CT) scan showing 80×70×60-mm tumor located in the left middle apex thoracic inlet. This tumor was located near the subclavian artery, and the subclavian lymph nodes were swollen. The tumor was found to be an adenocarcinoma (clinical-T3N3M0 stage IIIB). Therefore, we performed definitive chemoradiation therapy. Slight reduction in the tumor size was noted after

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2017 International journal of surgery case reports

29. Treatment of pancoast tumors from the surgeons prospective: re-appraisal of the anterior-manubrial sternal approach (PubMed)

Treatment of pancoast tumors from the surgeons prospective: re-appraisal of the anterior-manubrial sternal approach Pancoast tumours are now amenable to multimodality treatment with an acceptable survival. This is because trimodality treatment improves tumor sterilization and hence outcome. Moreover the development of an anterior approach to access the tumor, further improved the technical challenges for a sound resection.The Anterior-manubrial sternal approach was described more than a decade

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2010 Journal of cardiothoracic surgery

30. Point: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? Yes. (PubMed)

Point: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? Yes. 26110373 2016 04 27 2017 06 19 1931-3543 148 6 2015 Dec Chest Chest POINT: Is N2 Disease a Contraindication for Surgical Resection for Superior Sulcus Tumors? Yes. 1373-1375 S0012-3692(15)50097-4 10.1378/chest.15-1194 Tanner Nichole T NT Ralph H. Johnson Veterans Affairs Hospital, Health Equity and Rural Outreach Innovation Center, Charleston, SC; Division of Pulmonary and Critical Care, Allergy (...) Assessment (Health Care) Pancoast Syndrome diagnosis surgery Patient Selection Pneumonectomy methods Survival Analysis 2015 6 26 6 0 2015 6 26 6 0 2016 4 28 6 0 ppublish 26110373 S0012-3692(15)50097-4 10.1378/chest.15-1194

2015 Chest

31. Counterpoint: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? No. (PubMed)

Counterpoint: Is N2 disease a contraindication for surgical resection for superior sulcus tumors? No. 26110487 2016 04 27 2017 06 19 1931-3543 148 6 2015 Dec Chest Chest COUNTERPOINT: Is N2 Disease a Contraindication for Surgical Resection for Superior Sulcus Tumors? No. 1375-1379 S0012-3692(15)50098-6 10.1378/chest.15-1196 Li Wilson W WW Department of Cardiothoracic Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: w.w.li@amc.uva.nl (...) physiopathology surgery Combined Modality Therapy methods Humans Neoplasm Staging Outcome Assessment (Health Care) Pain Management methods Pain, Postoperative surgery Pancoast Syndrome diagnosis surgery Pneumonectomy adverse effects methods Prognosis Reoperation 2015 6 26 6 0 2015 6 26 6 0 2016 4 28 6 0 ppublish 26110487 S0012-3692(15)50098-6 10.1378/chest.15-1196

2015 Chest

32. Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm.

be given according to GCP and national regulations Exclusion criteria: Patients with central tumors < 2 cm of the proximal bronchial tree (Figure 2) or tumors immediately adjacent to mediastinal or pericardial pleura. Patients that receive sequential chemoradiotherapy or radiotherapy only. Patients with grade 3 dyspnea at baseline (according to CTCAE version 4.03) Patients with Pancoast tumors Prior radiotherapy treatment to the thorax Any contraindications to the administration of thoracic (...) Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm. Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2013 Clinical Trials

33. [Analysis of preoperative concurrent chemoradiotherapy in the treatment of patients with superior sulcus tumor of the lung]. (PubMed)

[Analysis of preoperative concurrent chemoradiotherapy in the treatment of patients with superior sulcus tumor of the lung]. Recently chemoradiotherapy becomes a standard treatment for un- resectable advanced non-small cell lung cancer (NSCLC) instead of radiotherapy alone. Superior sulcus tumor of the lung (Pancoast tumor) is a clinical subtype of NSCLC. The aim of this study is to compare the clinical effects and toxicities of preoperative concurrent chemoradiotherapy with radiotherapy alone (...) in patients with superior sulcus tumors.Fifty-six patients with superior sulcus tumors were divided randomly into two groups: twenty-six patients received concurrent chemoradiotherapy (chemoradiotherapy group), the other thirty patients received only radiotherapy (radiotherapy group). For both groups, the same radiation technic was given with the convention fraction. The total dose was 45Gy/25 fraction/5 weeks. For the chemoradiotherapy group, the patients were also given with concurrent chemotherapy

2012 Zhongguo fei ai za zhi = Chinese journal of lung cancer

34. Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously

of a history of an already proven disseminated disease. Patients having ≥ 2 peripheral lung metastases without unacceptable dose overlap. Exclusion Criteria: Patients with central tumors Pancoast tumors Prior radiotherapy treatment to the thorax Patients receiving any systemic treatment during SBRT Pregnant patients Patients previously treated with adriamycin agents in case of heart involvement within the treatment field. Contacts and Locations Go to Information from the National Library of Medicine (...) Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously Irradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2012 Clinical Trials

35. Transcervical Technic for Removal of Specimen from Superior Sulcus Tumor for Pathologic Study (PubMed)

Transcervical Technic for Removal of Specimen from Superior Sulcus Tumor for Pathologic Study 14129388 1996 12 01 2018 12 01 0003-4932 159 1964 Mar Annals of surgery Ann. Surg. TRANSCERVICAL TECHNIC FOR REMOVAL OF SPECIMEN FROM SUPERIOR SULCUS TUMOR FOR PATHOLOGIC STUDY. 407-10 MCGOON D C DC eng Journal Article United States Ann Surg 0372354 0003-4932 OM Adenocarcinoma, Mucinous Adenocarcinoma, Scirrhous Biopsy Carcinoma Carcinoma, Basal Cell Carcinoma, Squamous Cell Humans Lung Neoplasms (...) Pancoast Syndrome BIOPSY CARCINOMA, BASAL CELL CARCINOMA, EPIDERMOID CARCINOMA, MUCINOUS CARCINOMA, SCIRRHOUS LUNG NEOPLASMS PANCOAST'S SYNDROME 1964 3 1 1964 3 1 0 1 1964 3 1 0 0 ppublish 14129388 PMC1408573 Cleve Clin Q. 1962 Jul;29:135-43 13902348 J Thorac Surg. 1956 May;31(5):535-42 13320532 J Am Med Assoc. 1954 Jan 23;154(4):323-6 13108717 Ann Surg. 1961 Jul;154(1):29-40 17859668

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1964 Annals of Surgery

36. THE RÖNTGEN DIAGNOSTIC SIGNIFICANCE OF EROSION OF THE OPTIC CANALS IN THE STUDY OF INTRACRANIAL TUMORS (PubMed)

THE RÖNTGEN DIAGNOSTIC SIGNIFICANCE OF EROSION OF THE OPTIC CANALS IN THE STUDY OF INTRACRANIAL TUMORS 17856445 2007 09 17 2008 11 20 0003-4932 101 1 1935 Jan Annals of surgery Ann. Surg. THE RONTGEN DIAGNOSTIC SIGNIFICANCE OF EROSION OF THE OPTIC CANALS IN THE STUDY OF INTRACRANIAL TUMORS. 246-55 Pancoast H K HK eng Journal Article United States Ann Surg 0372354 0003-4932 1935 1 1 0 0 1935 1 1 0 1 1935 1 1 0 0 ppublish 17856445 PMC1391129

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1935 Annals of Surgery

37. Chest imaging

is considered medically necessary for diagnosis and management of the following findings or conditions when the results of imaging will impact treatment decisions. ? Hilar or mediastinal lymphadenopathy or mass ? Pancoast tumor ? Pleural mass ? Thymoma ? Benign tumors (pediatric only) IMAGING STUDY ADULT - CT chest - MRI chest for evaluation of mediastinal and hilar masses when CT is insufficient for problem solving or for evaluation of chest wall extension in Pancoast tumor PEDIATRIC - CT or MRI chest (...) and Inflammatory Conditions 10 Pneumonia 10 Other infectious or inflammatory conditions 10 Trauma 10 Blunt or penetrating trauma to the thorax 10 Tumor or Neoplasm 11 Chest wall mass 11 Pulmonary nodule 11 Other thoracic mass lesions 13 Parenchymal Lung Disease – not otherwise specified 14 Asbestos-related lesions involving the lungs and pleura (Adult only) 14 Bronchiectasis 14 Bronchiolitis obliterans 14 Interstitial lung disease and pulmonary fibrosis 14 Occupational lung disease (Adult only) 14 Pulmonary

2019 AIM Specialty Health

38. Thoracic Outlet Syndrome.

of US, sonographic diagnosis of compressive effects upon the brachial plexus is a challenge [34], and symptoms of TOS may unmask a deeper regional pathology such as Pancoast tumor or cervical spondylopathy, requiring further imaging. Computed Tomography Angiography Contrast-enhanced CT evaluation of TOS is typically performed as a 2-step procedure in which initial “neutral” images are obtained from elbow to aortic arch with the arms adducted to the side, followed by abduction and repeat imaging (...) Appropriateness Criteria ® 7 Imaging in the Diagnosis of Thoracic Outlet Syndrome 28. Davis GA, Knight SR. Pancoast tumors. Neurosurg Clin N Am. 2008;19(4):545-557, v-vi. 29. Gillard J, Perez-Cousin M, Hachulla E, et al. Diagnosing thoracic outlet syndrome: contribution of provocative tests, ultrasonography, electrophysiology, and helical computed tomography in 48 patients. Joint Bone Spine. 2001;68(5):416-424. 30. Stapleton C, Herrington L, George K. Sonographic evaluation of the subclavian artery during

2019 American College of Radiology

39. Appropriate Use Criteria: Imaging of the Chest

in immunosuppressed (e.g. HIV, after organ or bone marrow transplant, on infliximab or other tumor necrosis factor antagonists individual (In these individuals, a higher level of suspicion is warranted); OR ? Other etiologies for chronic cough which include, but are not limited to: ? Smoking ? Chronic bronchitis ? Cough-inducing medications (e.g., ACE inhibitors) ? Exposure to an environmental irritant ? Respiratory infection ? Neoplasm Fever of unknown origin ? Lasting more than three weeks with exceptions (...) /10744147 Sarcoidosis ? Initial evaluation and periodic follow-up Sternal infection and dehiscence Note: Rare complication of cardiothoracic surgery Structural abnormalities on chest X–ray, which require further clarification with CT Trauma ? Injury involving the chest wall, cardiomediastinal structures and/or lungs Tumor (primary neoplasm or metastatic disease) Management of biopsy-proven malignancy ? For renal cell carcinoma (where biopsy is contraindicated) when surgical resection is planned

2018 AIM Specialty Health

40. CRACKCast E071 – Ophthalmology Part A

used for motion sickness!!***** diagnosed when 1% pilocarpine has NO miosis effect on pupil size. Increases in light, usually have: ● PTOSIS ● EOM DYSFUNCTION ● DIPLOPIA when 1% pilocarpine instilled the pupil constricts! increases in darkness NO dilation lag NO loss of vision NO Diplopia YES dilation LAG–up to 15 secs caused by: ● strokes ● tumors ● lung CA ● thyroid adenomas ● pancoast’s tumours ● headache syndrome ● carotid dissection ● herpes zoster ● otitis media ● trauma to brachial plexus (...) during delivery Inadvertent anesthetic administration into carotid sheath during dental block…! 21) What is Horner’s syndrome? List 8 DDx. Horner’s syndrome: Due to an interruption of sympathetic innervation Ipsilateral: PTOSIS, MIOSIS, Facial ANHIDROSIS YES dilation LAG of the pupil– needing up to 15 secs to dilate with light Caused by: ● strokes ● tumors ● lung CA ● thyroid adenomas ● pancoast’s tumours ● headache syndrome ● carotid dissection ● herpes zoster ● otitis media ● trauma to brachial

2017 CandiEM

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