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Pain Sensation

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141. Pain Relief in Patients With Chronic Low Back Pain Using HeatTens vs. Standard Care.

Rating Scale (NRS) with the endpoints no pain" (0) and "excruciating pain" (10) Secondary Outcome Measures : 5 minute walk test (5MWT) [ Time Frame: Change from Baseline 5MWT after treatment and at 4 weeks ] Subjects need to walk as far as possible in 5 minutes Pressure Pain Threshold (PPT) [ Time Frame: Change from Baseline Pressure Pain Threshold after treatment and at 4 weeks ] This measures deep tissue hyperalgesia, defined as the point at witch the pressure sensation turned into pain. Temporal (...) Pain Relief in Patients With Chronic Low Back Pain Using HeatTens vs. Standard Care. Pain Relief in Patients With Chronic Low Back Pain Using HeatTens vs. Standard Care. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

142. Pain Modulatory Profiles in Massage for Individuals With Neck Pain

pain symptom intensity rated as 4/10 or higher during the last 24 hours neck pain for greater than or equal to 3 months Exclusion Criteria: non-English speaking systemic medical conditions known to affect sensation (e.g. diabetes, hypertension) history of neck surgery or fracture within the past 6 months current history of chronic pain condition other than neck pain diagnosis of cervical radiculopathy or cervical myelopathy history of whiplash; g) currently using blood thinning medication any blood (...) Pain Modulatory Profiles in Massage for Individuals With Neck Pain Pain Modulatory Profiles in Massage for Individuals With Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pain Modulatory Profiles

2018 Clinical Trials

143. Changes of Pain and Functional Parameters in Back Pain Patients Over Time

Date : December 2020 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Changes from baseline pain sensation at 1, 2, 3, 4, 5 and 9 months [ Time Frame: 6 measurement time points through study completion, an average of 9 months ] Changes of pain, sensory malfunction and numbness assessed by pain drawings and the visual analog scale. The visual analog scale ranges from 0 to 10 points, where 0 (...) indicates no pain, no numbness or no impairment of sensation and 10 stands for the highest pain value, total numbness or unsustainable paresthesia. Secondary Outcome Measures : Changes from baseline neurological status at 1, 2, 3, 4, 5 and 9 months [ Time Frame: 6 measurement time points through study completion, an average of 9 months ] The neurological status will be assessed by the straight leg raise test. The hydrogoniometer serves as assessment tool and measures the range of motion in degrees

2018 Clinical Trials

144. Effects of Transcranial Direct Current Stimulation on Knee Osteoarthritis Pain in Elderly Subjects With Defective Endogenous Pain-Inhibitory Systems: Protocol for a Randomized Controlled Trial. (PubMed)

effects on a significant group of subjects. In addition to this, pharmacological treatments often cause adverse effects, which limits their use on this population. Previous studies showed that chronic knee OA pain may be associated with maladaptive compensatory plasticity in pain-related neural central circuits indexed by a defective descending pain-inhibitory system. Transcranial direct current stimulation (tDCS) can revert some of these maladaptive changes, thus decreasing chronic pain sensation (...) Effects of Transcranial Direct Current Stimulation on Knee Osteoarthritis Pain in Elderly Subjects With Defective Endogenous Pain-Inhibitory Systems: Protocol for a Randomized Controlled Trial. Knee osteoarthritis (OA) has been the main cause behind chronic pain and disabilities in the elderly population. The traditional treatment for knee OA pain currently concerns a number of combinations of pharmacological and nonpharmacological therapies. However, such combinations have displayed little

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2018 JMIR Research Protocols

145. Imagining My Painful Hand Is Not Mine: Self-Distancing Relieves Experimental Acute Pain Induced by a Cold Pressor Task. (PubMed)

group), and the posttest CPT. The participants were to adopt the designated perspective only during the posttest CPT. The results showed that 1) maintaining a self-distanced perspective while experiencing pain decreased the sensation of pain, relative to the self-immersed group and the control group; and (2) compared with the control group, maintaining a self-immersed perspective neither alleviated nor aggravated the pain. This result supports that self-distancing could relieve the acute pain (...) Imagining My Painful Hand Is Not Mine: Self-Distancing Relieves Experimental Acute Pain Induced by a Cold Pressor Task. Self-distancing has been shown to alleviate emotional pain and to have potential efficacy for treating chronic pain and imagined acute pain, relative to self-immersing. This study examined the efficacy of self-distancing in relieving acute physical pain caused by a cold pressor task (CPT) in healthy adults. A total of 65 undergraduates were assigned pseudorandomly to 1 of 3

2018 The journal of pain : official journal of the American Pain Society

146. The added value of bedside examination and screening QST to improve neuropathic pain identification in patients with chronic pain (PubMed)

, von Frey hair], and vibration). The NASQ paradigm (pressure algometry, electrical pain thresholds, and conditioned pain modulation) was assessed in 58 patients to generate new insights.BSE revealed a low association of differences between patients with either absent or present NePC: heat, cold, and pricking sensations with a von Frey hair were statistically significantly less common in patients with present NePC. NASQ did not reveal any differences between patients with and without (...) The added value of bedside examination and screening QST to improve neuropathic pain identification in patients with chronic pain The assessment of a neuropathic pain component (NePC) to establish the neurological criteria required to comply with the clinical description is based on history taking, clinical examination, and quantitative sensory testing (QST) and includes bedside examination (BSE). The objective of this study was to assess the potential association between the clinically

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2018 Journal of pain research

147. Pain quality descriptors and sex-related differences in patients with shoulder pain (PubMed)

sensations (eg, sore, pulled, torsion, and taut) were relatively more predominant than superficial pain sensations (eg, pricking and lacerating). In terms of sex-related differences, female patients used more pain quality descriptors than the male patients (5.5 vs 3.7, P<0.001). The frequency of paroxysmal, dullness, and constriction-related pain quality descriptors, such as "shooting", "faint", "clicking", and "squeezing", were higher in females than in males (all P<0.05).The results provide commonly (...) Pain quality descriptors and sex-related differences in patients with shoulder pain Pain quality assessment is applicable to pain evaluation and treatment. However, shoulder pain quality descriptors mostly remain unknown. Furthermore, sex-related differences considerably affect clinical pain experience. The aim of this study was to investigate pain quality descriptors and to compare sex-related differences in using pain descriptors among patients with shoulder pain.A sample of 120 patients (41

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2018 Journal of pain research

148. A Journey to Learn about Pain – a book about pain education for children

about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain conditions other than CRPS, and people without any chronic pain condition. The survey takes approximately 20 minutes and the responses are anonymous. Prof Paul Hodges on pain (...) A Journey to Learn about Pain – a book about pain education for children A Journey to Learn about Pain - a book about pain education for children Research into the role of the brain and mind in chronic pain A Journey to Learn about Pain – a book about pain education for children November 9, 2018 by Persistent pain in children is an increasingly recognized clinical problem with high prevalence rates found in some populations. A conservative estimate posits that 20% to 35% of children

2018 Body in Mind blog

149. Experimental pain tolerance is decreased and independent of clinical pain intensity in patients with endometriosis. (PubMed)

Experimental pain tolerance is decreased and independent of clinical pain intensity in patients with endometriosis. To investigate alterations in tactile, pain thresholds and pain tolerance thresholds in patients with endometriosis using a multimodality approach.Cross-sectional study.Multidisciplinary referral center.Women with proven endometriosis (N = 35) and healthy controls (N = 38).Pain processing was tested using quantitative sensory testing (QST) to investigate sensation, pain, and pain (...) tolerance thresholds for thermal, electrical, and pressure stimuli.Differences in QST measures in patients with endometriosis and in healthy controls on the endometriosis site and control sites, and the association between QST outcomes and patient characteristics.We observed a significantly decreased pain tolerance in patients with endometriosis, independent of clinical pain intensity or revised American Society for Reproductive Medicine stage, compared with healthy controls.Increasing knowledge

2018 Fertility and Sterility

150. Pain Sensory Profile Changes Following Treatment of Chronic Low Back Pain

tolerable (pain tolerance threshold, PTT) are measured with a computer controlled pressure cuff. The cuff is placed on the lower leg and is gradually inflated (1kPa/sec). The first onset of pain (VAS 1, measured on an electronic VAS scale: 0=no pain, 10=worst pain imaginable) is indicated when the sensation of pressure around the leg changes to pain. The pressure continues to rise until the PTT is reached. PTT is defined as the point where the subject cannot endure more increase in pressure. Sensitivity (...) Pain Sensory Profile Changes Following Treatment of Chronic Low Back Pain Pain Sensory Profile Changes Following Treatment of Chronic Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pain

2018 Clinical Trials

151. How does prolonged experimental back pain alter measures of pain inhibition and facilitation?

your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain conditions other than CRPS, and people without any chronic pain (...) How does prolonged experimental back pain alter measures of pain inhibition and facilitation? How does back pain alter measures of pain inhibition and facilitation? Research into the role of the brain and mind in chronic pain How does prolonged experimental back pain alter measures of pain inhibition and facilitation? November 2, 2018 by Facilitation of central pain mechanisms is proposed to be a potential missing link between identifiable tissue damage and the severity of pain experienced

2018 Body in Mind blog

152. Investigating the effects of three needling parameters (manipulation, retention time, and insertion site) on needling sensation and pain profiles: a study of eight deep needling interventions. (PubMed)

Investigating the effects of three needling parameters (manipulation, retention time, and insertion site) on needling sensation and pain profiles: a study of eight deep needling interventions. Introduction. In traditional Chinese acupuncture, needle sensation (deqi) is purported to contribute to a therapeutic outcome. While researchers have attempted to define deqi qualitatively, few have examined the effects of needling parameters on its intensity. Methods. 24 healthy subjects completed eight (...) interventions scheduled at least one week apart, which involved manual acupuncture to LI4 or a designated nonacupoint (NAP) on the hand, with real or simulated manipulation each three minutes and needle retentions of one or 21 minutes. Intensities of needling sensation and pain were reported every three minutes and sensation qualities were reported post-intervention. Results. Immediately after needle insertion, similar levels of mean needle sensation and of pain were reported independent of intervention

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2013 Evidence-based Complementary and Alternative Medicine (eCAM)

153. The Use of a CoolSense Device to Lower Pain Sensation During Finger Pricking While Measuring Blood Glucose in Diabetes Patients-A Randomized Placebo. (PubMed)

The Use of a CoolSense Device to Lower Pain Sensation During Finger Pricking While Measuring Blood Glucose in Diabetes Patients-A Randomized Placebo. Patients with type 1 diabetes and a significant portion of patients with type 2 diabetes must use subcutaneous insulin injections, in order to maintain normoglycemia and to prevent immediate and long-term complications. For these patients, testing blood glucose levels more frequently is necessary to safely achieve glycated hemoglobin targets (...) . In the current study, the effects of a CoolSense™ device (CoolSense Medical Ltd., Tel Aviv, Israel) were examined in relieving pain caused by needle-pricking for glucose measurements in adult patients with diabetes.One hundred seventy-seven patients assessed the severity of pain they experienced during needle-pricking. The patients were randomly divided into an experimental group or a control group that used either a cooled CoolSense instrument or a non-cooled device, respectively. Participants were asked

2013 Diabetes technology & therapeutics

154. Motor and parietal cortex stimulation for phantom limb pain and sensations. (PubMed)

Motor and parietal cortex stimulation for phantom limb pain and sensations. Limb amputation may lead to chronic painful sensations referred to the absent limb, ie phantom limb pain (PLP), which is likely subtended by maladaptive plasticity. The present study investigated whether transcranial direct current stimulation (tDCS), a noninvasive technique of brain stimulation that can modulate neuroplasticity, can reduce PLP. In 2 double-blind, sham-controlled experiments in subjects with unilateral (...) lower or upper limb amputation, we measured the effects of a single session of tDCS (2 mA, 15 min) of the primary motor cortex (M1) and of the posterior parietal cortex (PPC) on PLP, stump pain, nonpainful phantom limb sensations and telescoping. Anodal tDCS of M1 induced a selective short-lasting decrease of PLP, whereas cathodal tDCS of PPC induced a selective short-lasting decrease of nonpainful phantom sensations; stump pain and telescoping were not affected by parietal or by motor tDCS

2013 Pain

155. The Origin of Phantom Limb Sensation and Phantom Limb Pain in Amputees

The Origin of Phantom Limb Sensation and Phantom Limb Pain in Amputees The Origin of Phantom Limb Sensation and Phantom Limb Pain in Amputees - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Origin (...) of Phantom Limb Sensation and Phantom Limb Pain in Amputees The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01936558 Recruitment Status : Unknown Verified January 2014 by National Taiwan University Hospital. Recruitment status was: Recruiting First Posted : September 6, 2013 Last Update Posted : January

2013 Clinical Trials

156. The amygdala between sensation and affect: a role in pain (PubMed)

The amygdala between sensation and affect: a role in pain The amygdala is a structure of the temporal lobe thought to be involved in assigning emotional significance to environmental information and triggering adapted physiological, behavioral and affective responses. A large body of literature in animals and human implicates the amygdala in fear. Pain having a strong affective and emotional dimension, the amygdala, especially its central nucleus (CeA), has also emerged in the last twenty years (...) as key element of the pain matrix. The CeA receives multiple nociceptive information from the brainstem, as well as highly processed polymodal information from the thalamus and the cerebral cortex. It also possesses the connections that allow influencing most of the descending pain control systems as well as higher centers involved in emotional, affective and cognitive functions. Preclinical studies indicate that the integration of nociceptive inputs in the CeA only marginally contributes to sensory

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2013 Journal of Molecular Psychiatry

157. Sterile water injections for acute low back pain

and radiating sensation on palpation) points, using a 2 mL plastic syringe with an 0.40 mm diameter (27 gauge) needle. 0.5 mL of sterile water to create a bleb at each injection site. 3-5 injections in rapid succession, with a break of 1-2 min before further injections. Comparator: what was the control/alternative? Isotonic saline was used rather than water. The same pain physician administered all injections. Outcomes: what was measured? Primary outcome: pain intensity (VAS), recorded at baseline, 10, 45 (...) Sterile water injections for acute low back pain Sterile water injections for acute low back pain – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2016\/10\/cover-mo-oct2016-p62-3.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Oct 10 2016 Sterile water injections for acute low back pain

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2016 Morsels of Evidence

158. Sterile water injections for acute low back pain

and radiating sensation on palpation) points, using a 2 mL plastic syringe with an 0.40 mm diameter (27 gauge) needle. 0.5 mL of sterile water to create a bleb at each injection site. 3-5 injections in rapid succession, with a break of 1-2 min before further injections. Comparator: what was the control/alternative? Isotonic saline was used rather than water. The same pain physician administered all injections. Outcomes: what was measured? Primary outcome: pain intensity (VAS), recorded at baseline, 10, 45 (...) Sterile water injections for acute low back pain Sterile water injections for acute low back pain – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2016\/10\/cover-mo-oct2016-p62-3.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Oct 10 2016 Sterile water injections for acute low back pain

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2016 Morsels of Evidence

159. Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip

. Overall incidence of AEs was similar across subgroups. AEs of abnormal peripheral sensation were more frequently reported in tanezumab-treated patients compared with placebo or active comparator. Patients receiving active comparator had a slightly higher incidence of AEs suggestive of postganglionic sympathetic dysfunction.Tanezumab consistently provided significant improvement of pain, physical function, and PGA in individuals with OA, including patients with diabetes, severe OA symptoms, or aged ≥65 (...) Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip A pooled analysis was conducted to evaluate tanezumab efficacy and safety in patients with osteoarthritis (OA), including subgroup analyses of at-risk patients with diabetes, severe OA symptoms, and those aged ≥65 years.Data from phase III placebo-controlled clinical trials of patients with moderate-to-severe OA of the knee or hip were

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2019 EvidenceUpdates

160. Persistent Pain with Breastfeeding

for vasospasm of the nipple. Allodynia/functional pain Allodynia is de?ned as sensation of pain in response to a stimulus,suchaslighttouch,whichwouldnotnormallyelicit pain.Breastallodyniacanoccurinisolationorinthecontext of other pain disorders, such as irritable bowel syndrome, ?bromyalgia, interstitial cystitis, migraines, temporoman- dibular joint disorders (TMJ), and pain with intercourse. Taking a careful history to assess for other pain disorders is important for informing treatment (...) Persistent Pain with Breastfeeding ABM Protocol ABM Clinical Protocol #26: Persistent Pain with Breastfeeding Pamela Berens, 1 Anne Eglash, 2 Michele Malloy, 2 Alison M. Steube, 3,4 and the Academy of Breastfeeding Medicine A central goal of The Academy of Breastfeeding Medicine is the development of clinical protocols for man- aging common medical problems that may impact breastfeeding success. These protocols serve only as guidelines for the care of breastfeeding mothers and infants and do

2016 Academy of Breastfeeding Medicine

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