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Pain Sensation

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61. Sensation and Skin Pressures Under Blood-Draw Tourniquets

will also track changes in skin surface pressures and pain levels over this prolonged tourniquet application. Hypothesis: The investigators hypothesize the use of common elastic tourniquets used for blood draws does not significantly impact sensation and will not elicit nerve or tissue damage. Technologies used: Monofilaments and Pressure Sensor Condition or disease Intervention/treatment Phase Skin Pressures Under Blood Draw-tourniquets Other: Sensation and Skin Surface Pressures Under Blood-Draw (...) Sensation and Skin Pressures Under Blood-Draw Tourniquets Sensation and Skin Pressures Under Blood-Draw Tourniquets - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sensation and Skin Pressures Under Blood

2017 Clinical Trials

62. Spiders, ladybugs and bees: A case of unusual sensations in a child with cingulate epilepsy Full Text available with Trip Pro

Spiders, ladybugs and bees: A case of unusual sensations in a child with cingulate epilepsy Cingulate epilepsy is a rare form of epilepsy. Seizures from the anterior cingulate may present with mood change, fear, hypermotor activity, and autonomic signs, while posterior cingulate seizures resemble temporal lobe seizures. We describe a child with cingulate epilepsy who experienced unpleasant/painful sensory phenomenon. The sensations were described as spiders crawling on his forehead/right leg (...) , ladybugs causing right ear pain and bees stinging his head/right extremities. Unpleasant sensory phenomenon/pain are rarely reported in cingulate epilepsy. Recognizing the role of the cingulate in producing pain/unusual sensory phenomenon is important, and may have localizing value when evaluating children for epilepsy surgery.

2017 Epilepsy & behavior case reports

63. Neural correlates of evoked phantom limb sensations Full Text available with Trip Pro

Neural correlates of evoked phantom limb sensations Previous work showed the existence of changes in the topographic organization within the somatosensory cortex (SI) in amputees with phantom limb pain, however, the link between nonpainful phantom sensations such as cramping or tingling or the percept of the limb and cortical changes is less clear. We used functional magnetic resonance imaging (fMRI) in a highly selective group of limb amputees who experienced inducible and reproducible (...) nonpainful phantom sensations. A standardized procedure was used to locate body sites eliciting phantom sensations in each amputee. Selected body sites that could systematically evoke phantom sensations were stimulated using electrical pulses in order to induce phasic phantom sensations. Homologous body parts were also stimulated in a group of matched controls. Activations related to evoked phantom sensations were found bilaterally in SI and the intraparietal sulci (IPS), which significantly correlated

2017 Biological psychology

64. Relationships between catastrophic thought, bodily sensations and physical symptoms Full Text available with Trip Pro

Relationships between catastrophic thought, bodily sensations and physical symptoms Researchers have recently begun to seek cognitive explanations for physical symptoms with no obvious biological cause. Concepts such as somatization, somatosensory amplification, and somatosensory catastrophizing have been invoked to explain these phenomena. Somatosensory amplification occurs when these bodily sensations become stronger and more painful. Somatosensory catastrophizing is the tendency to attribute (...) these bodily sensations to unbearable functional modulation or as signs of serious illness. This causes the sufferer to pay excessive attention to these physical sensations. However, there is no scale for evaluating somatosensory catastrophizing, and there are no standard diagnostic criteria. There were two objectives for this study: to develop a scale for evaluating somatosensory catastrophizing and to investigate relationships between somatosensory amplification, somatosensory catastrophizing

2017 BioPsychoSocial medicine

65. Absent monofilament sensation in a type 2 diabetic feet Full Text available with Trip Pro

Absent monofilament sensation in a type 2 diabetic feet Neuropathy is a common complication which can affect up to 90% of patients with diabetes mellitus. Asymptomatic neuropathy is a common presentation. We present a case that emphasises the importance of foot screening in people with diabetes. It also highlights that patient education is key to prevent development of foot ulceration which can lead to amputations. In addition, pharmacological therapy (as per NICE guidance) can be offered (...) for pain relief. Patients with diabetic neuropathy are at high risk of falling and sustaining fractures.

2017 London journal of primary care

66. Acute corneal epithelial debridement unmasks the corneal stromal nerve responses to ocular stimulation in rats: implications for abnormal sensations of the eye Full Text available with Trip Pro

Acute corneal epithelial debridement unmasks the corneal stromal nerve responses to ocular stimulation in rats: implications for abnormal sensations of the eye It is widely accepted that the mechanisms for transducing sensory information reside in the nerve terminals. Occasionally, however, studies have appeared demonstrating that similar mechanisms may exist in the axon to which these terminals are connected. We examined this issue in the cornea, where nerve terminals in the epithelial cell (...) layers are easily accessible for debridement, leaving the underlying stromal (axonal) nerves undisturbed. In isoflurane-anesthetized rats, we recorded extracellularly from single trigeminal ganglion neurons innervating the cornea that are excited by ocular dryness and cooling: low-threshold (<2°C cooling) and high-threshold (>2°C) cold-sensitive plus dry-sensitive neurons playing possible roles in tearing and ocular pain. We found that the responses in both types of neurons to dryness, wetness

2017 Journal of neurophysiology

67. Investigation of the Phenomenon of Propagated Sensation along the Channels in the Upper Limb Following Administration of Acupuncture and Mock Laser. Full Text available with Trip Pro

Investigation of the Phenomenon of Propagated Sensation along the Channels in the Upper Limb Following Administration of Acupuncture and Mock Laser. Similar to De Qi psychophysical responses, propagated sensation along the channels (PSC) is considered an important phenomenon in traditional Chinese acupuncture. In acupuncture clinical trials, different acupuncture manipulation techniques are used to enhance the propagation of sensation along the channels to facilitate an optimum therapeutic (...) result.To examine and compare the PSC reported by participants in a clinical trial following the administration of acupuncture and inactive mock laser.The study was embedded in a two-arm parallel design multicenter, randomized clinical trial, the Tennis Elbow Acupuncture-International Study-China, Hong Kong, Australia, Italy (TEA IS CHAI). Needle sensations were measured using a validated instrument, the Massachusetts General Hospital Acupuncture Sensation Spreading Scale. Ninety-six participants

2017 Journal of acupuncture and meridian studies Controlled trial quality: uncertain

68. Central mechanisms of airway sensation and cough hypersensitivity. Full Text available with Trip Pro

Central mechanisms of airway sensation and cough hypersensitivity. The airway sensory nervous system is composed of two anatomically distinct processing pathways that allow for the production of respiratory reflexes and voluntary evoked respiratory behaviours in response to sensing an airway irritation. Disordered sensory processing is a hallmark feature of many pulmonary disorders and results in the development of cough hypersensitivity syndrome, characterised by chronic cough and a persistent (...) urge-to-cough in affected individuals. However, the mechanism underpinning how the airway sensory circuits become disordered, especially at the level of the central nervous system, is not well understood. In this mini-review we present well-defined mechanisms that lead to the development of chronic pain as a framework to explore the evidence that cough disorders may manifest due to neuroplasticity and sensitisation of important components of the airway sensory circuitry in the brain. We highlight

2017 Pulmonary Pharmacology & Therapeutics

69. Mas-Related G Protein-Coupled Receptors and the Biology of Itch Sensation. (Abstract)

Mas-Related G Protein-Coupled Receptors and the Biology of Itch Sensation. Chronic, persistent itch is a devastating symptom that causes much suffering. In recent years, there has been great progress made in understanding the molecules, cells, and circuits underlying itch sensation. Once thought to be carried by pain-sensing neurons, itch is now believed to be capable of being transmitted by dedicated sensory labeled lines. Members of the Mas-related G protein-coupled receptor (Mrgpr) family (...) on the role of Mrgprs in mediating itch sensation.

2017 Annual Review of Genetics

70. The Japanese Version of the Massachusetts General Hospital Acupuncture Sensation Scale: A Validation Study. Full Text available with Trip Pro

of the 12 descriptors included in the Japanese MASS. The content validity ratios for 10 of the 12 descriptors were 0.33 or greater. 42 healthy subjects then evaluated acupuncture sensations evoked by manual acupuncture at LI4 using the Japanese MASS. Cronbach's alpha was 0.86. The correlation coefficient of total MASS scores and total Short Form McGill Pain Questionnaire scores and MASS indices and sensory visual analogue scores were 0.78 and 0.80, respectively. Factor analysis loaded the 12 descriptors (...) The Japanese Version of the Massachusetts General Hospital Acupuncture Sensation Scale: A Validation Study. Acupuncture sensations are considered essential in producing the treatment effect of acupuncture. The Massachusetts General Hospital Acupuncture Sensation Scale (MASS) is a frequently used scale in acupuncture research to measure acupuncture sensations. We translated the MASS into Japanese (Japanese MASS) based on Beaton's guidelines. 30 acupuncturists evaluated the relevancy and meaning

2017 Evidence-based Complementary and Alternative Medicine (eCAM)

71. Distraction From Itch Shows Brainstem Activation Without Reduction in Experimental Itch Sensation. Full Text available with Trip Pro

the participants have to decide if the colour of the writing corresponds to the written word, for example if "red" is written in red or not) were counterbalanced during the scanning to examine task-specific changes in blood oxygenation level dependent-signal. The intensity of the subjects' itch sensation, desire to scratch and pain sensation were evaluated. Distraction by a Stroop task did not reduce itch intensity or urge to scratch. However, the Stroop task led to significantly higher activation of the left (...) brainstem when it followed the "pure" itch sensation. Itch and pain seem to have similar inhibition pathways, particularly concerning brainstem activation during distraction. But as itch sensation, in contrast to pain, could not be sufficiently reduced by distraction, both entities might have different modulation systems.

2017 Acta Dermato-Venereologica

72. A glucagon-like peptide-1 analog, liraglutide improves visceral sensation and gut permeability in rats. Full Text available with Trip Pro

A glucagon-like peptide-1 analog, liraglutide improves visceral sensation and gut permeability in rats. A glucagon-like peptide-1 analog, liraglutide, has been reported to block inflammatory somatic pain. We hypothesized that liraglutide attenuates lipopolysaccharide (LPS)-induced and repeated water avoidance stress (WAS)-induced visceral hypersensitivity and tested the hypothesis in rats.The threshold of the visceromotor response induced by colonic balloon distention was measured to assess (...) visceral sensation. Colonic permeability was determined in vivo by quantifying the absorbed Evans blue spectrophotometrically, which was instilled in the proximal colon for 15 min. The interleukin-6 level in colonic mucosa was also quantified using ELISA.Subcutaneously injected LPS (1 mg/kg) reduced the visceromotor response threshold after 3 h. Liraglutide (300 μg/kg subcutaneously) at 15 h and 30 min before injecting LPS eliminated LPS-induced allodynia. It also blocked the allodynia induced

2017 Journal of gastroenterology and hepatology

73. Relationships between the paradoxical painful and non painful sensations induced by a thermal grill. (Abstract)

Relationships between the paradoxical painful and non painful sensations induced by a thermal grill. The simultaneous application of innocuous cutaneous warm and cold stimuli with a thermal grill can induce both paradoxical pain and paradoxical warmth (heat). The goal of this study was to investigate further the relationships between these paradoxical sensations. Stimuli were applied to the palms of the right hands of 21 volunteers with a thermode consisting of 6 bars, the temperature of which (...) by paradoxical pain. The difference between the cold-warm temperatures eliciting paradoxical warmth was significantly smaller than that producing paradoxical pain. The intensities of the warmth and unpleasantness evoked by the stimuli were directly related to the magnitude of the warm-cold differential. Our results suggest that there is a continuum between the painful and nonpainful paradoxical sensations evoked by the thermal grill that may share pathophysiological mechanisms. These data also confirm

2014 Pain

74. Is there any documented evidence for the use of acupuncture to treat phantom limb pain and phantom limb sensation in an absent arm? I am aware of a case report from 2004 in patients with absent legs.

Is there any documented evidence for the use of acupuncture to treat phantom limb pain and phantom limb sensation in an absent arm? I am aware of a case report from 2004 in patients with absent legs. Is there any documented evidence for the use of acupuncture to treat phantom limb pain and phantom limb sensation in an absent arm? I am aware of a case report from 2004 in patients with absent legs. - Trip Database NEW! Google+ Find evidence fast ALL of these words: Title only Anywhere (...) documented evidence for the use of acupuncture to treat phantom limb pain and phantom limb sensation in an absent arm? I am aware of a case report from 2004 in patients with absent legs. Answered Follow us: © 2020 Trip Database Ltd. company number 04316414. Trip is proud to be made in the UK.

2012 TRIP Answers

75. Senza spinal cord stimulation system for delivering HF10 therapy to treat chronic neuropathic pain

-of-rights). Page 3 of 171 1 Recommendations Recommendations 1.1 The case for adopting Senza spinal cord stimulation (SCS) for delivering HF10 therapy as a treatment option for chronic neuropathic back or leg pain after failed back surgery is supported by the evidence. HF10 therapy using Senza SCS is at least as effective as low-frequency SCS in reducing pain and functional disability, and avoids the experience of tingling sensations (paraesthesia). 1.2 Senza SCS for delivering HF10 therapy should (...) data. Senza spinal cord stimulation system for delivering HF10 therapy to treat chronic neuropathic pain (MTG41) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 12 of 17A Av voiding par oiding paraesthesia aesthesia 4.3 People having low-frequency SCS often experience paraesthesia (or tingling sensations), but this is not the case with high-frequency SCS (such as Senza). The experts explained that people may have

2019 National Institute for Health and Clinical Excellence - Medical technologies

76. AIM Clinical Appropriateness Guidelines for Interventional Pain Management

AIM Clinical Appropriateness Guidelines for Interventional Pain Management Appropriate.Safe.Affordable © 2019 AIM Specialty Health 2062-0119 V.3 Interventional Pain Management Guidelines Musculoskeletal Program Clinical Appropriateness Guidelines Interventional Pain Management EFFECTIVE JANUARY 01, 2019 LAST REVIEWED SEPTEMBER 12, 2018 Copyright © 2019. AIM Specialty Health. All Rights Reserved. Interventional Pain Management 2 Table of Contents Description and Application of the Guidelines 3 (...) Joint Injection 19 Description 19 General Requirements 19 Criteria 19 Exclusions 21 Selected References 21 CPT/HCPCS Codes 21 History 21 Spinal Cord Stimulators 22 Description 22 General Requirements 22 Criteria 23 Selected References 23 CPT/HCPCS Codes 23 History 24 Copyright © 2019. AIM Specialty Health. All Rights Reserved. Interventional Pain Management 3 Description and Application of the Guidelines AIM’s Clinical Appropriateness Guidelines (hereinafter “AIM’s Clinical Appropriateness

2019 AIM Specialty Health

77. Chronic Pelvic Pain

Chronic Pelvic Pain Chronic Pelvic Pain | Uroweb › Chronic Pelvic Pain Chronic Pelvic Pain To access the pdfs & translations of individual guidelines, please as EAU member. Non-EAU members can view the web versions. To become an EAU member, click . D. Engeler (Chair), A.P. Baranowski, B. Berghmans, J. Borovicka, A.M. Cottrell, P.S. Elneil, J. Hughes, E. Messelink (Vice-chair), A.C. de C Williams Guidelines Associates: L. Pacheco-Figueiredo, B. Parsons, S. Goonewardene TABLE OF CONTENTS (...) REFERENCES 1. Fall, M., et al., EAU Guidelines on Chronic Pelvic Pain., In: EAU Guidelines on Chronic Pelvic Pain. Presented at the 18th EAU Annual Congress Madrid 2003. 2003, European Association of Urology: Arnhem. 2. Fall, M., et al. EAU guidelines on chronic pelvic pain. Eur Urol, 2004. 46: 681. 3. Fall, M., et al., EAU Guidelines on Chronic Pelvic Pain, In: EAU Guidelines on Chronic Pelvic Pain. Presented at the 18th EAU Annual Congress Barcelona 2010. 2010, EAU: Arnhem. 4. Fall, M., et al. EAU

2019 European Association of Urology

78. Mindfulness and CBT for chronic low back pain

(body scan, yoga, and meditation – attention to thoughts emotions, and sensations in the present moment without trying to change them, sitting meditation with awareness of breathing, and walking meditation). CBT The CBT intervention included techniques most commonly applied and studied for chronic LBP. The program included: psychoeducation about chronic pain, the relationships between thoughts and emotional and physical reactions, sleep hygiene, relapse prevention, and maintenance of gains (...) Mindfulness and CBT for chronic low back pain RACGP - Mindfulness and CBT for chronic low back pain Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship

2017 Handbook of Non-Drug interventions (HANDI)

79. Tramadol for neuropathic pain in adults. Full Text available with Trip Pro

Tramadol for neuropathic pain in adults. This review is an update of a review of tramadol for neuropathic pain, published in 2006; updating was to bring the review in line with current standards. Neuropathic pain, which is caused by a lesion or disease affecting the somatosensory system, may be central or peripheral in origin. Peripheral neuropathic pain often includes symptoms such as burning or shooting sensations, abnormal sensitivity to normally painless stimuli, or an increased sensitivity (...) to normally painful stimuli. Neuropathic pain is a common symptom in many diseases of the peripheral nervous system.To assess the analgesic efficacy of tramadol compared with placebo or other active interventions for chronic neuropathic pain in adults, and the adverse events associated with its use in clinical trials.We searched CENTRAL, MEDLINE, and Embase for randomised controlled trials from inception to January 2017. We also searched the reference lists of retrieved studies and reviews, and online

2017 Cochrane

80. Morphine for chronic neuropathic pain in adults. Full Text available with Trip Pro

Morphine for chronic neuropathic pain in adults. Neuropathic pain, which is caused by a lesion or disease affecting the somatosensory system, may be central or peripheral in origin. Neuropathic pain often includes symptoms such as burning or shooting sensations, abnormal sensitivity to normally painless stimuli, or an increased sensitivity to normally painful stimuli. Neuropathic pain is a common symptom in many diseases of the nervous system. Opioid drugs, including morphine, are commonly used (...) to treat neuropathic pain. Most reviews have examined all opioids together. This review sought evidence specifically for morphine; other opioids are considered in separate reviews.To assess the analgesic efficacy and adverse events of morphine for chronic neuropathic pain in adults.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase for randomised controlled trials from inception to February 2017. We also searched the reference lists of retrieved studies

2017 Cochrane

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