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Pain Sensation

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441. Corneal Sensation and Dry Eye Symptoms after Conventional versus Inverted Side-Cut Femtosecond LASIK: A Prospective Randomized Study. (Abstract)

, linear-scaled Quality of Vision questionnaire.Objective corneal sensation and self-reported light sensitivity, dryness, foreign body sensation, and pain/discomfort.Preoperative corneal sensation as measured by mean Cochet-Bonnet aethesiometry was equal between the inverted and conventional side cut groups but was better in eyes with an inverted side cut compared with a conventional side cut at all postoperative months (inverted vs. conventional: 1 month, 14.5 vs. 13.2 mm; 3 months, 24.9 vs. 18.4 mm (...) Corneal Sensation and Dry Eye Symptoms after Conventional versus Inverted Side-Cut Femtosecond LASIK: A Prospective Randomized Study. To compare corneal sensation and self-reported dry eye symptoms after femtosecond-assisted LASIK with conventional versus inverted side cuts.Prospective, randomized, eye-to-eye study.A total of 120 eyes in 60 participants with myopia.Fellow eyes were randomized to receive femtosecond-assisted LASIK with a conventional 70-degree side cut made with the 60 kHz

2014 Ophthalmology Controlled trial quality: uncertain

442. Recurrent facial erythema with burning sensation and increased temperature: a variant of erythromelalgia or a new entity? Full Text available with Trip Pro

Recurrent facial erythema with burning sensation and increased temperature: a variant of erythromelalgia or a new entity? Erythromelalgia is a rare clinical syndrome characterized by episodic attacks of burning pain, erythema, and increased temperature, primarily affecting the extremities, and in rare instances, involving the ear, face, neck, and the scrotum. The dermatoscopic features of erythromelalgia in a case with solely facial involvement have never been described previously.We describe (...) a 14-year-old female who presented with erythema, burning sensation, and warmth on her face only, which mimic the features of erythromelalgia. Physical examination showed higher temperature on the involved cheeks than on axillas during the episode, while the temperature on both areas was the same between episodes. Dermatoscope showed more dilated vessels inside the erythema during the episodes than between the episodes. The symptoms had excellent response to the combination treatment of gabapentin

2014 Pain Medicine

443. TRP Channel Cannabinoid Receptors in Skin Sensation, Homeostasis, and Inflammation Full Text available with Trip Pro

TRP Channel Cannabinoid Receptors in Skin Sensation, Homeostasis, and Inflammation In the skin, cannabinoid lipids, whether of endogenous or exogenous origin, are capable of regulating numerous sensory, homeostatic, and inflammatory events. Although many of these effects are mediated by metabotropic cannabinoid receptors, a growing body of evidence has revealed that multiple members of the transient receptor potential (TRP) ion channel family can act as "ionotropic cannabinoid receptors (...) ". Furthermore, many of these same TRP channels are intimately involved in cutaneous processes that include the initiation of pain, temperature, and itch perception, the maintenance of epidermal homeostasis, the regulation of hair follicles and sebaceous glands, and the modulation of dermatitis. Ionotropic cannabinoid receptors therefore represent potentially attractive targets for the therapeutic use of cannabinoids to treat sensory and dermatological diseases. Furthermore, the interactions between neurons

2014 ACS chemical neuroscience

444. Piezo2 is the major transducer of mechanical forces for touch sensation in mice Full Text available with Trip Pro

complete deficit in light-touch sensation in multiple behavioural assays, without affecting other somatosensory functions. Our results highlight that a single ion channel that displays rapidly adapting, mechanically activated currents in vitro is responsible for the mechanosensitivity of most low-threshold mechanoreceptor subtypes involved in innocuous touch sensation. Notably, we find that touch and pain sensation are separable, suggesting that as-yet-unknown mechanically activated ion channel(s) must (...) Piezo2 is the major transducer of mechanical forces for touch sensation in mice The sense of touch provides critical information about our physical environment by transforming mechanical energy into electrical signals. It is postulated that mechanically activated cation channels initiate touch sensation, but the identity of these molecules in mammals has been elusive. Piezo2 is a rapidly adapting, mechanically activated ion channel expressed in a subset of sensory neurons of the dorsal root

2014 Nature

445. Coping with Common GI Symptoms in the Community: A Global Perspective on Heartburn, Constipation, Bloating, and Abdominal Pain/Discomfort

and description • A chronic, localized or diffuse unpleasant feeling or pain in the abdominal cavity. • Dyspepsia (or indigestion) is a chronic or recurrent pain in the upper abdomen, with a sensation of fullness and early satiety when eating. It may be accompanied by bloating, belching, nausea, or heartburn. It is frequently associated with GERD and may be the first symptom of peptic ulcer disease and occasionally of gastric cancer. 4.2 Epidemiological notes • Several studies have reported prevalences (...) Coping with Common GI Symptoms in the Community: A Global Perspective on Heartburn, Constipation, Bloating, and Abdominal Pain/Discomfort © World Gastroenterology Organisation, 2013 World Gastroenterology Organisation Global Guidelines Coping with common GI symptoms in the community A global perspective on heartburn, constipation, bloating, and abdominal pain/discomfort May 2013 Review Team Richard Hunt (co-chair, Canada/UK) Eamonn Quigley (co-chair, USA) Zaigham Abbas (Pakistan) Abraham

2013 World Gastroenterology Organisation

446. An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 1 - Introduction and General Considerations

, emotional, and social components. Even though both chronic pain and chronic pain syndrome can coexist and are defined in terms of duration and the persistence of the sensation of pain and the pres- ence or absence of psychological and emotional com- ponents, they are 2 separate entities. Unlike chronic pain, chronic pain syndrome encompasses the added components of certain recognizable psychological and socioeconomic influences and characteristic psychologi- cal and sociological behavioral patterns (...) An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 1 - Introduction and General Considerations In 2011, the Institute of Medicine (IOM) re-engineered its definition of clinical guidelines as follows: “clinical practice guidelines are statements that include recommendations intended to optimize patient care that are informed by a systematic review of evidence and an assessment of the benefit and harms of alternative care options

2013 American Society of Interventional Pain Physicians

447. An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 2 - Guidance and Recommendations

An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 2 - Guidance and Recommendations Objective: To develop evidence-based clinical practice guidelines for interventional techniques in the diagnosis and treatment of chronic spinal pain. Methodology: Systematic assessment of the literature. Evidence: I. Lumbar Spine • The evidence for accuracy of diagnostic selective nerve root blocks is limited; whereas for lumbar provocation (...) discography, it is fair. • The evidence for diagnostic lumbar facet joint nerve blocks and diagnostic sacroiliac intraarticular injections is good with 75% to 100% pain relief as criterion standard with controlled local anesthetic or placebo blocks. • The evidence is good in managing disc herniation or radiculitis for caudal, interlaminar, and transforaminal epidural injections; fair for axial or discogenic pain without disc herniation, radiculitis or facet joint pain with caudal, and interlaminar

2013 American Society of Interventional Pain Physicians

448. Hip Pain and Mobility Deficits ? Hip Osteoarthritis

with central pain sensitization and chronic conditions such as OA, and there is growing interest in its potential to in- form clinical decision making and research. 64 Although hy- peralgesia may occur in response to mechanical, thermal, or chemical stimuli, the literature is most well developed in the area of mechanical hyperalgesia. 4 A mechanical pressure al- gometer is commonly used to measure pressure pain thresh- old (PPT), defined as the minimal amount of pressure at which the sensation of pressure (...) first changes to a sensation of pain. Typically, PPTs are measured in a variety of body locations, and low values in locations away from the primary painful site are used as an indicator of central pain sensitiza- tion. Emerging research has demonstrated a strong negative correlation between PPT and pain severity in patients with hip OA. 76 Wylde et al 76 found a strong negative correlation between PPT measured at the forearm and pain severity as measured by the WOMAC pain subscale in 254 patients

2017 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

449. Neck Pain

Neck Pain Clinical Practice Guidelines PETER R. BLANPIED, PT , PhD • ANITA R. GROSS, PT , MSc • JAMES M. ELLIOTT , PT , PhD • LAURIE LEE DEVANEY, PT , MSc DEREK CLEWLEY, DPT • DAVID M. WALTON, PT , PhD • CHERYL SPARKS, PT , PhD • ERIC K. ROBERTSON, PT , DPT Neck Pain: Revision 2017 Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health From the Orthopaedic Section of the American Physical Therapy Association J Orthop Sports Phys Ther (...) : Impairment/Function-Based Diagnosis A11 CLINICAL GUIDELINES: Examination A18 CLINICAL GUIDELINES: Interventions A25 AUTHOR/REVIEWER AFFILIATIONS AND CONTACTS A44 REFERENCES A45 Journal of Orthopaedic & Sports Physical Therapy® Downloaded from www.jospt.org at on July 7, 2017. For personal use only. No other uses without permission. Copyright © 2017 Journal of Orthopaedic & Sports Physical Therapy®. All rights reserved.Neck Pain: Clinical Practice Guidelines Revision 2017 a2 | july 2017 | volume 47

2017 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

450. Pelvic Girdle Pain in the Antepartum Population: Physical Therapy Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health From the Section on Women's Health and the Orthopaedic Section of the America

Pelvic Girdle Pain in the Antepartum Population: Physical Therapy Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health From the Section on Women's Health and the Orthopaedic Section of the America 7/7/2017 Pelvic Girdle Pain in the Antepartum Population: Physical T... : Journal of Women’s Health Physical Therapy http://journals.lww.com/jwhpt/Fulltext/2017/05000/Pelvic_Girdle_Pain_in_the_Antepartum_Population__.7.aspx 1/27 Pelvic Girdle (...) Pain in the Antepartum Population: Physical Therapy Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health From the Section on Women's Health and the Orthopaedic Section of the American Physical Therapy Association Clinton, Susan C. PT, DScPT, OCS, WCS, FAAOMPT ; Newell, Alaina PT, DPT, WCS, CLT­LANA ; Downey, Patricia A. PT, PhD, DPT ; Ferreira, Kimberly PT, PhD, MSPT Journal of Women's Health Physical Therapy: May 2017 ­ Volume 41 ­ Issue 2

2017 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

451. Assessment and Management of Pain (Third Edition)

Assessment and Management of Pain (Third Edition) Clinical Best Practice Guidelines DECEMBER 2013 Assessment and Management of Pain Third EditionDisclaimer These guidelines are not binding on nurses or the organizations that employ them. The use of these guidelines should be flexible, and based on individual needs and local circumstances. They neither constitute a liability nor discharge from liability. While every effort has been made to ensure the accuracy of the contents at the time (...) and published in its entirety, without modification, in any form, including in electronic form, for educational or non-commercial purposes. Should any adaptation of the material be required for any reason, written permission must be obtained from the Registered Nurses’ Association of Ontario. Appropriate credit or citation must appear on all copied materials as follows: Registered Nurses’ Association of Ontario (2013). Assessment and Management of Pain (3 rd ed.). T oronto, ON: Registered Nurses

2013 Registered Nurses' Association of Ontario

452. Neuropathic pain - a management update

features include reduced sensation protein immunoelectrophoresis and thyroid function. Assessing glycaemic control with an hbA1c is useful in patients who are diabetic. A glucose tolerance test may be helpful if diabetic status is not known. current evidence-based recommended treatments for neuropathic pain conditions are outlined in Table 1; medications and suggested treatment doses are outlined in Table 2. Diabetic polyneuropathy it is estimated that 3.6% of Australians have diabetes and about 10 (...) of injury that has gone unnoticed due to the loss of sensation. Rare episodes of painful DPn have been reported with acute ketoacidosis and even in patients with tight glycaemic control. in these cases, the pain is nocturnal and is described as ‘burning’ and is exacerbated by light touch (eg. bedding or clothing). examination reveals hyperalgesia, but little in the way of sensory or motor loss. Differential diagnoses are extensive, including neurotoxicity (eg. from medications or heavy metals

2013 Clinical Practice Guidelines Portal

453. Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome. Full Text available with Trip Pro

thermal lumbar sympathectomy with lumbar sympathetic neurolysis using phenol in 20 participants with CRPS. There was no comparison of sympathectomy versus sham or placebo. No dichotomous pain outcomes were reported. Average baseline scores of 8-9/10 on several pain scales fell to about 4/10 initially (1 day) and remained at 3-5/10 over four months. There were no significant differences between groups, except for "unpleasant sensation", which was higher with radiofrequency ablation. One participant (...) Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome. This review is an update on 'Sympathectomy for neuropathic pain' originally published in Issue 2, 2003. The concept that many neuropathic pain syndromes (traditionally this definition would include complex regional pain syndromes (CRPS)) are "sympathetically maintained pains" has historically led to treatments that interrupt the sympathetic nervous system. Chemical sympathectomies use alcohol

2010 Cochrane

454. A 54 yo male with sudden chest pain. Computer says normal. Paramedic disagrees.

learned. I am sure that MDs can learn too! Posted by Steve Smith at Labels: , , Reactions: 18 comments: This is almost exactly how I presented when I called for EMS and I'm a 30 year Paramedic. I did not have "pain", just a slight pressure sensations across my chest with diaphoresis. EKG interpretation was just "abnormal", no suspected MI indicated. On arrival at the E.D. my CPKs were elevated slightly and troponin was barely elevated (E.R. Doc's words). Cardiologist came to evaluate me and suggested (...) A 54 yo male with sudden chest pain. Computer says normal. Paramedic disagrees. Dr. Smith's ECG Blog: A 54 yo male with sudden chest pain. Computer says normal. Paramedic disagrees. Monday, November 27, 2017 Announcement! There is now an Android app for the 3- and 4-variable formulas. It is of course free (#FOAMed). It was written by Yannick Schäfer (a medical student in France): Remember there is also an iPhone app called "SubtleSTEMI" Case This was sent by a very astute paramedic. A 54 year

2017 Dr Smith's ECG Blog

455. Lidocaine and Benzocaine are Equally Effective in Reducing Pain from Injection of Needles

. The use of topical lidocaine or benzocaine in gel or ointment form is feasible in most dental settings, whereas the use of a transoral lidocaine patch may be less feasible in some dental settings. Utilization of topical anesthesia is very likely to be accepted by the average patient as the benefits of reducing needle injection pain and reducing discomfort/anxiety during dental procedures outweigh the harms/risks of experiencing a temporary unpleasant taste or temporary unpleasant sensation (...) Lidocaine and Benzocaine are Equally Effective in Reducing Pain from Injection of Needles UTCAT2174, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Lidocaine and Benzocaine are Equally Effective in Reducing Pain from Injection of Needles Clinical Question For a patient receiving an intraoral anesthetic injection, will topical benzocaine as compared with topical lidocaine decrease the pain score felt by the patient

2012 UTHSCSA Dental School CAT Library

456. Pain education enhances the pain-relieving effect of exercise in healthy adults

their future. Study recruitment is being conducted separately for both young people and parents. Please email if you would like to take part. Participants will be paid for their time. It’s impossible to slip your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help (...) Pain education enhances the pain-relieving effect of exercise in healthy adults Pain education enhances the pain-relieving effect of exercise Research into the role of the brain and mind in chronic pain Pain education enhances the pain-relieving effect of exercise in healthy adults December 1, 2017 by Exercise may be one of the most universally beneficial interventions for people with chronic pain. Despite this, many patients with chronic pain avoid exercise because it can worsen their pain

2017 Body in Mind blog

457. The lived experience of pain-related fear in people with low back pain

, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain conditions other than CRPS, and people without any chronic pain condition. The survey takes approximately 20 minutes and the responses are anonymous. Prof Paul Hodges on pain and altered movement Am I safe to move? Listen to Lorimer (...) The lived experience of pain-related fear in people with low back pain The lived experience of pain-related fear in people with low back pain • Body in Mind Research into the role of the brain and mind in chronic pain The lived experience of pain-related fear in people with low back pain August 14, 2017 by This post is the fifth in a about chapters in the edited collection, . — For many people low back pain (LBP) is scary. The spine is commonly perceived to be the structure linking our limbs

2017 Body in Mind blog

458. How does watching a parent in pain impact children’s own pain experiences?

conducted separately for both young people and parents. Please email if you would like to take part. Participants will be paid for their time. It’s impossible to slip your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out (...) How does watching a parent in pain impact children’s own pain experiences? How does watching a parent in pain impact children’s own pain experiences? • Body in Mind Research into the role of the brain and mind in chronic pain How does watching a parent in pain impact children’s own pain experiences? September 15, 2017 by Pain problems tend to run in families; if you have a parent with chronic pain you are also more likely to experience chronic pain yourself 1 . While a simple explanation

2017 Body in Mind blog

459. When pain kills – chronic pain and chronic diseases

part. Participants will be paid for their time. It’s impossible to slip your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain (...) When pain kills – chronic pain and chronic diseases When pain kills – chronic pain and chronic diseases • Body in Mind Research into the role of the brain and mind in chronic pain When pain kills – chronic pain and chronic diseases October 13, 2017 by One high profile campaign to raise awareness of persistent pain uses the tagline ‘persistent pain doesn’t kill, but it does ruin lives’. This is a fair argument, but recent data raise the possibility of an increased risk of death from other

2017 Body in Mind blog

460. When pain kills – chronic pain and chronic diseases

part. Participants will be paid for their time. It’s impossible to slip your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain (...) When pain kills – chronic pain and chronic diseases When pain kills – chronic pain and chronic diseases • Body in Mind Research into the role of the brain and mind in chronic pain When pain kills – chronic pain and chronic diseases October 13, 2017 by One high profile campaign to raise awareness of persistent pain uses the tagline ‘persistent pain doesn’t kill, but it does ruin lives’. This is a fair argument, but recent data raise the possibility of an increased risk of death from other

2017 Body in Mind blog

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