How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

9,613 results for

Pain Sensation

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

401. Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)

to 10). "0" in this case means "no pain". Each "pricking", "stinging" or "burning" sensation is defined as a painful sensation, which should always be evaluated by giving a value greater than "0". "10" corresponds to the individual maximum pain imaginable. Change from baseline to Week 12 in the pressure pain threshold (PPT) ratio for the thenar muscle/abductor hallucis muscle. [ Time Frame: Change from baseline (Visit 2 [Day 1]) to Visit 8 (Week 12) ] Pressure pain threshold: using a pressure (...) Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS) Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

402. The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain

, SI14, and Hyeopcheok (Huatuo Jiaji, EX B2) points at C3-5 levels). Device: Acupuncture Acupuncture will be performed with manual stimulation (needle twirling) to evoke de-qi sensation. Acupuncture sessions will be conducted 2 times a week for 5 weeks (total 10 sessions). Outcome Measures Go to Primary Outcome Measures : Difference between visual analogue scale (VAS) of neck pain for the past 3 days at 5 weeks post-baseline and baseline [ Time Frame: Week 5 post-baseline (screening) ] VAS uses (...) The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

403. A New Experimental Model of Transient and Short-lasting Muscle Pain in Humans Based on Diathermy

sensation is obtained according to the subjective criterion of the volunteer. This sensation should be mild or moderate pain, but tolerable for the duration of the application. Once the first application is completed, the volunteer will be allowed to rest for a period of 10 minutes, and the assessment will be repeated to test for possible after effects. After it is verified that the muscles recovered their normal temperature and the pain sensation has completely disappeared, the variables related (...) undesired heating effects. Afterwards the emission mode (continuous or pulsed) will be selected, and application of SWD will start. The intensity of SWD will be gradually increased until the volunteer perceives a warm sensation, and once familiarized with this perception, the intensity will be increased until a sensation of constant but tolerable pain is evoked. This sensation will be maintained throughout the duration of the SWD application, estimated in approximately 10 minutes. Outcome Measures Go

2018 Clinical Trials

404. Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain

: Diabetic Peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). Among several complications that contribute to reduce patient's quality of life and life expectancy diabetic neuropathy (DN) generalized or focal leads to an impaired life quality. The clinical symptoms of DPN range from pain and burning sensations, more at rest or at night; to hypoesthesia or paresthesia, and or numbness. Different types of peripheral neuropathy are observed in diabetes, axonal or demyelination (...) Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Perineural Platelet-rich Plasma

2018 Clinical Trials

405. Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing

Not Applicable Detailed Description: The subjects are being asked to consider participation in this research study. The purpose of this study is to see if incorporating mindfulness exercises prior to urodynamic studies (UDS) results in less pain, anxiety and discomfort. The participants will be guided through a mindfulness meditation exercise by a licensed professional. During this exercise participants will be asked to focus attention on breathing, physical sensations, and thoughts. This exercise will last (...) Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

406. Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies

in pain sensitivity [ Time Frame: change from baseline PPT at six weeks ] pressure pain threshold (PPT) was measured with digital algometer. Pressure pain threshold which identifies minimum levels increasing mechanical stimulus is gold standard method for measuring pain sensitivity. PPT was measured from cervical vertebrae's spinous process and muscle belly's. Algometer range was set 0 kgF to 12kgF. Higher values represent increased pressure sensation. Secondary Outcome Measures : change in Light (...) Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2018 Clinical Trials

407. Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy

from the first spray ] Discomfort will be scored as VAS on a scale of 1 to 10 (1 is least, 10 is most) Prevalence of adverse effects of pre-medication [ Time Frame: four minutes from the first spray ] allergy, burning pain, altered taste, chocking sensation, headache will be asked and recorded Pain due to procedure as VAS 1-10 [ Time Frame: At the end of the procedure ] Pain will be scored as VAS on a scale of 1 to 10 (1 is least, 10 is most) Ease of procedure as VAS 1-10 [ Time Frame: At the end (...) Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2018 Clinical Trials

408. The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain

The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

409. Lidocaine Jelly for Pain Control During Mohs Surgery

stage of surgery, an identical wound dressing will be placed on the operative site. Immediately prior to each subsequent stage of surgery, we will assess patients' pain sensation, and additional lidocaine/epinephrine will be injected if needed. After the surgical site is re-anesthetized, vital signs will be recorded and the Pain/Anxiety survey administered immediately prior to the first incision of that stage. Study Design Go to Layout table for study information Study Type : Interventional (...) Lidocaine Jelly for Pain Control During Mohs Surgery Lidocaine Jelly for Pain Control During Mohs Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidocaine Jelly for Pain Control During Mohs Surgery

2018 Clinical Trials

410. Virtual Reality for Chronic Neuropathic Pain

occurs, the spinal somatosensory circuit is thought to generate aberrant nociceptive impulses that the brain interprets as pain. Thalamic circuits may also serve as amplifiers of nociceptive signals. Sensory deafferentation after injury to the spinal cord produces extensive and long-lasting reorganization of the cortical and subcortical sensory maps. It has been suggested that pain and phantom limb sensations are the consequence of those cortical plasticity change. Therefore, strategies aimed (...) Virtual Reality for Chronic Neuropathic Pain Virtual Reality for Chronic Neuropathic Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Virtual Reality for Chronic Neuropathic Pain The safety

2018 Clinical Trials

411. Dry Needling for Patients With Back Pain

, ankylosing spondylitis, cauda equina). Use of high doses of blood thinners Evidence of central nervous system involvement, to include hyperreflexia, sensory disturbances in the lower extremity, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, the presence of pathological reflexes (i.e. positive Hoffman's and/or Babinski reflexes), etc. Workers compensation or pending legal action regarding their back pain (...) Dry Needling for Patients With Back Pain Dry Needling for Patients With Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Dry Needling for Patients With Back Pain The safety and scientific validity

2018 Clinical Trials

412. The Effect of Lower Limbs Neural Mobilization in Subjects With Cervical Pain.

: Active Mobilization of the sciatic nerve The subjects, receive an active sciatic nerve mobilization intervention. Outcome Measures Go to Primary Outcome Measures : Pain level at rest [ Time Frame: Change from baseline in Visual Analog Scale at 2 minutes after intervention ] A Visual Analog Scale, will be used for recording level of pain at rest. The VAS evaluates levels of pain intensity using an 10-point scale (range 0-10), with 0 being classified as "no sensation" and 10 "pain as bad as could (...) The Effect of Lower Limbs Neural Mobilization in Subjects With Cervical Pain. The Effect of Lower Limbs Neural Mobilization in Subjects With Cervical Pain. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

413. Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 20 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Adults with age of 20 years old or above Patients with symptoms of unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than six months duration (...) Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Low Energy Shock Wave for the Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

414. D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain

of catastrophic cognitions in the sensation of pain. The scale ranges from 1 (not at all) to 4 (always). Multidimensional Assessment of Interoceptive Awareness (MAIA) [ Time Frame: 12 weeks ] A 32-item self-reported measure delineating between beneficial versus maladaptive interoceptive attention. Oswestry Disability Index (ODI) [ Time Frame: 12 weeks ] A 10-item self-reported measure quantifying a subjective percentage score of level of function (disability) in activities of daily living in those (...) D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. D-cycloserine

2018 Clinical Trials

415. Self-management Program in Chronic Pelvic Pain

sensations, reinterpreting pain sensation, hoping and cognitive distracting) and maladaptive coping (catastrophizing, and faithing and praying). Participants score each item using a 7-point scale to indicate how often they use that strategy to manage their pain (0 never, 3 sometimes, and 6 always) Secondary Outcome Measures : Change in performance of activities [ Time Frame: Change from baseline self-perceived performance at 7 weeks ] Canadian Occupational Performance Measure will be used to evaluate (...) Self-management Program in Chronic Pelvic Pain Self-management Program in Chronic Pelvic Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Self-management Program in Chronic Pelvic Pain The safety

2018 Clinical Trials

416. Day to Day Variation of Pressure Pain Threshold and Muscle Hardness

, and many migraine patients have symptoms from their neck and muscles. 50% of migraine patients have a sensation of stiff neck in relation to migraine attacks. Furthermore it is well established, that migraine patients have tender muscles during migraine attack, which can be measured with pressure pain threshold. In this study the investigators aim to establish the variation in ultrasound elastography and pressure pain threshold in migraine patients over time. And establish the significance of headache (...) Day to Day Variation of Pressure Pain Threshold and Muscle Hardness Day to Day Variation of Pressure Pain Threshold and Muscle Hardness - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Day to Day Variation

2018 Clinical Trials

417. Pain Outcomes Following Intralesional Corticosteroid Injections

and corticosteroids despite a lack of evidence that the use of lidocaine improves pain. Due to the acidic pH, the lidocaine component of the injection can actually cause a significant burning sensation during the procedure. Lidocaine does not have anti-inflammatory properties and does not treat the underlying pathology. By including another medication, lidocaine also adds cost and risk to the procedure. The purpose of this study is to see if removing lidocaine from intralesional injections decreases the pain (...) Pain Outcomes Following Intralesional Corticosteroid Injections Pain Outcomes Following Intralesional Corticosteroid Injections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pain Outcomes Following

2018 Clinical Trials

418. Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain

) is the second most frequent chronic pain condition in the United States and results in billions of dollars each year in health care expenses, disability and lost productivity. A major factor that contributes to the refractory nature of cLBP is enhanced pain sensitivity, which is an altered state of pain processing that amplifies pain sensation and impairs descending pain inhibition. Enhanced pain sensitivity in patients who develop cLBP is associated with altered expression of pro-nociceptive (...) that suggests specific LBP as determined by Dr. Kim such as conditions or medications that can affect pain sensitivity injury to non-dominant hand or presence of open skin lesions, disturbed sensation, carpal tunnel or rash Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier

2018 Clinical Trials

419. The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) Full Text available with Trip Pro

The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) To evaluate associations between sensations of ocular itch and dry eye (DE) symptoms, including ocular pain, and DE signs.A cross-sectional study of 324 patients seen in the Miami Veterans Affairs eye clinic was performed. The evaluation consisted of questionnaires regarding ocular itch, DE symptoms, descriptors of neuropathic-like ocular pain (NOP), and evoked pain sensitivity (...) (abnormal matrix metalloproteinase 9 testing) which was less common in those with moderate-severe ocular itch symptoms, DE signs were not related to ocular itch. Individuals with moderate-severe ocular itch also demonstrated greater sensitivity to evoked pain on the forearm and had higher non-ocular pain, depression, and post-traumatic stress disorders scores, compared to those with no or mild itch symptoms.Subjects with moderate-severe ocular itch symptoms have more severe symptoms of DE, NOP, non

2018 Transactions of the American Ophthalmological Society

420. Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation Full Text available with Trip Pro

by I234T, and confirmed that the I234T conductance could drastically depolarize DRG neurons, resulting in loss of excitability. We conclude that attenuation of pain sensation by I234T is caused by massively depolarized membrane potential of some DRG neurons which is partly due to enhanced overlap between activation and fast-inactivation, impairing their ability to fire. Our results demonstrate how a Nav1.7 mutation that produces channel gain-of-function can contribute to a dual clinical presentation (...) that includes loss of pain sensation at the clinical level.

2018 Scientific reports

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>