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Pain Sensation

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381. Perceptual Distortions in Acute Neck Pain

), a real needle will be shown to the participants to imitate and produce the anticipation of a pain experience. A pinprick sensation will be produced by a weighted stimulus applied perpendicularly to the skin without piercing the skin. A stimulus of 512 millinewtons (mN) will be used to produce a pinprick sensation and activation of cutaneous nociceptors. Adhesive tapes covering stimulation points will also be provided. The stimuli will be applied in exactly the same spot as the real injection (...) in previous experimental condition. Other Name: Pain induced by sham injection No Intervention: Control Participants in the control condition will not receive any kind of pain or pinprick sensation. Outcome Measures Go to Primary Outcome Measures : Tactile acuity measured by two-point discrimination test (TPD). [ Time Frame: TPD change from baseline at 30 seconds post-manipulation period (e.g. saline injection). ] Mechanical callipers will be delicately applied to the spot just below the location where

2018 Clinical Trials

382. Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

pain. Opioid consumption [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3, 6, 9, and 12 ] All opioids consumed (reported as oral morphine equivalents) Non-painful phantom limb sensations frequency [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3, 6, 9, and 12 ] non-painful sensations referred to the lost body part (frequency) Non-painful phantom limb sensations duration [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3, 6, 9, and 12 ] non-painful (...) sensations referred to the lost body part (duration) Phantom limb pain frequency [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3, 6, 9, and 12 ] painful sensations referred to the lost body part (frequency) Phantom limb pain average duration [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3, 6, 9, and 12 ] painful sensations referred to the lost body part (average duration) Residual limb pain frequency [ Time Frame: Baseline, postoperative days 1, 2 and 8; Months 1, 3

2018 Clinical Trials

383. Incidence of Postoperative Pain After Glide Path Preparation Using Three Different Instruments

University Information provided by (Responsible Party): Cangül Keskin, Ondokuz Mayıs University Study Details Study Description Go to Brief Summary: Endodontic postoperative pain is described as a sensation of discomfort following the completion of root canal treatment and is experienced by the 25-40% of the patients regardless of pulp and periradicular diseases (1, 2). Prevalence of pain has been reported to decrease from 40% in the first 48 hours to 11% after 7 days (2). Mechanisms of endodontic (...) Incidence of Postoperative Pain After Glide Path Preparation Using Three Different Instruments Incidence of Postoperative Pain After Glide Path Preparation Using Three Different Instruments - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

384. Effectiveness of Physical Therapy Interventions for Low Back Pain Targeting the Low Back Only or Low Back Plus Hips

Effectiveness of Physical Therapy Interventions for Low Back Pain Targeting the Low Back Only or Low Back Plus Hips Effectiveness of Physical Therapy Interventions for Low Back Pain Targeting the Low Back Only or Low Back Plus Hips - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Effectiveness of Physical Therapy Interventions for Low Back Pain Targeting the Low Back Only or Low Back Plus Hips The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

385. Postoperative Pain and Discomfort After Orbital Decompression

represents the worst discomfort; this scale has been confirmed to be sensitive and reliable. Discomfort was defined as "sensation other than pain" and included nausea, vomiting, headache, and dizziness. Clinically significant postoperative discomfort was considered serious discomfort (NRS score ≥5) any time postoperatively. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family (...) Postoperative Pain and Discomfort After Orbital Decompression Postoperative Pain and Discomfort After Orbital Decompression - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Postoperative Pain and Discomfort

2018 Clinical Trials

386. Effects of Hipopressive Exercises in Nonspecific Low Back Pain

Effects of Hipopressive Exercises in Nonspecific Low Back Pain Effects of Hipopressive Exercises in Nonspecific Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Hipopressive (...) Exercises in Nonspecific Low Back Pain (HPvsMT-LBP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03565926 Recruitment Status : Completed First Posted : June 21, 2018 Last Update Posted : August 20, 2018 Sponsor: University of Valencia Information provided by (Responsible Party): GEMMA V ESPÍ LÓPEZ

2018 Clinical Trials

387. Cryoanalgesia to Prevent Acute and Chronic Pain Following Mastectomy and Limb Amputation: A Randomized, Double-Masked, Sham-Controlled Study

months 1, 3, 6, and 12 ] How many times in the previous 3 days subject experienced phantom pain (the number of times experienced--not based on a scale or instrument) Phantom sensation incidence [ Time Frame: Postoperative months 1, 3, 6, and 12 ] How many times in the previous 3 days subject experienced phantom sensations (the number of times experienced--not based on a scale or instrument) Residual limb or wound pain incidence [ Time Frame: Postoperative months 1, 3, 6, and 12 ] How many times (...) in the previous 3 days subject experienced residual limb or wound pain (the number of times experienced--not based on a scale or instrument) Phantom pain duration [ Time Frame: Postoperative months 1, 3, 6, and 12 ] The average duration of phantom pain occurrences in the previous 3 days Phantom sensation incidence [ Time Frame: Postoperative months 1, 3, 6, and 12 ] The average duration of phantom sensation occurrences in the previous 3 days Residual limb or wound pain duration [ Time Frame: Postoperative

2018 Clinical Trials

388. Paracetamol and Neuropathic Pain

Paracetamol and Neuropathic Pain Paracetamol and Neuropathic Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Paracetamol and Neuropathic Pain (PAeoNy) The safety and scientific validity of this study (...) -Ferrand Study Details Study Description Go to Brief Summary: The aim of this study is to evaluate the analgesic effect of paracetamol in patients suffering from pain with a peripheral neuropathic component in the presence of their usual treatment. Condition or disease Intervention/treatment Phase Neuropathic Pain Drug: paracetamol Other: Placebo comparator Phase 2 Detailed Description: This is an interventional, randomized, placebo-controlled, double-blind, crossover study about the use of paracetamol

2018 Clinical Trials

389. Floating for Chronic Pain

Floating for Chronic Pain Floating for Chronic Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Floating for Chronic Pain (Float4Pain) The safety and scientific validity of this study (...) Study Details Study Description Go to Brief Summary: In recent years there has been a novel approach for the treatment of chronic pain: Floatation REST (restricted environmental stimulation therapy). Floating is a therapeutic approach, in which patients float in a specialized pool or tank on water that contains high concentrations of Epsom salt (Magnesium sulfate). Water is kept at skin temperature (35-36°C) and the pool or tank is shielded to provide almost complete darkness and silence

2018 Clinical Trials

390. Botulinum Toxin Injections for Oral Neuropathic Pain

to the conclusions of the European task force committee for intraoral quantitative sensory testing (QST), the QST is defined by : Brush-induced allodynia will be evaluated stroking the skin with a standardized brush and will be considered as present if evoking a clear sensation of pain. The intensity of allodynia will be recorded on a 100 mm visual analog scale. Area of Brush-induced allodynia will be traced on a transparent plastic foil, and then digitized for measurement on Image J software. Mechanical (...) sensations (detection thresholds to non-painful stimuli) and pain thresholds will be measured with calibrated von Frey hairs (0.06-300gm) (Bioseb, France) (or electronic von Frey, Bioseb France). Thermal sensations and pain thresholds (in °C) will be assessed with a thermoalgometer (TSA II; Medoc, Israel) with an intraoral thermode by the method of limits, with baseline temperatures adjusted to the patient's skin temperature . Emotional state with Hospital Anxiety and Depression Scale (HADS) [ Time Frame

2018 Clinical Trials

391. Spinal Cord Burst Stimulation for Chronic Radicular Pain Following Lumbar Spine Surgery

has been to replace the pain sensation with paresthesia. The anticipation is that the electrical current alters pain processing by masking the sensation of pain with a comfortable tingling or paresthesia. Although patients mostly cope with paresthesia, a significant proportion reports that the sensation is unpleasant. 'Burst' SCS utilizes complex programming to deliver high-frequency stimuli. This SCS technique seems to provide paresthesia-free stimulation, resulting in better pain relief of low (...) back and leg pain then traditional tonic stimulation. The widespread use of SCS has not been backed by solid evidence. The absence of placebo-controlled trials has long been an important point of criticism, but due to the nature of the intervention with sensation of paresthesia, studies with placebo control have so far not been considered possible. When 'burst' SCS is used the stimulation is often unnoticed by the patient, allowing comparison with placebo stimulation. The aim of this randomized

2018 Clinical Trials

392. Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)

to 10). "0" in this case means "no pain". Each "pricking", "stinging" or "burning" sensation is defined as a painful sensation, which should always be evaluated by giving a value greater than "0". "10" corresponds to the individual maximum pain imaginable. Change from baseline to Week 12 in the pressure pain threshold (PPT) ratio for the thenar muscle/abductor hallucis muscle. [ Time Frame: Change from baseline (Visit 2 [Day 1]) to Visit 8 (Week 12) ] Pressure pain threshold: using a pressure (...) Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS) Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

393. The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain

, SI14, and Hyeopcheok (Huatuo Jiaji, EX B2) points at C3-5 levels). Device: Acupuncture Acupuncture will be performed with manual stimulation (needle twirling) to evoke de-qi sensation. Acupuncture sessions will be conducted 2 times a week for 5 weeks (total 10 sessions). Outcome Measures Go to Primary Outcome Measures : Difference between visual analogue scale (VAS) of neck pain for the past 3 days at 5 weeks post-baseline and baseline [ Time Frame: Week 5 post-baseline (screening) ] VAS uses (...) The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain The Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more

2018 Clinical Trials

394. A New Experimental Model of Transient and Short-lasting Muscle Pain in Humans Based on Diathermy

sensation is obtained according to the subjective criterion of the volunteer. This sensation should be mild or moderate pain, but tolerable for the duration of the application. Once the first application is completed, the volunteer will be allowed to rest for a period of 10 minutes, and the assessment will be repeated to test for possible after effects. After it is verified that the muscles recovered their normal temperature and the pain sensation has completely disappeared, the variables related (...) undesired heating effects. Afterwards the emission mode (continuous or pulsed) will be selected, and application of SWD will start. The intensity of SWD will be gradually increased until the volunteer perceives a warm sensation, and once familiarized with this perception, the intensity will be increased until a sensation of constant but tolerable pain is evoked. This sensation will be maintained throughout the duration of the SWD application, estimated in approximately 10 minutes. Outcome Measures Go

2018 Clinical Trials

395. Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain

: Diabetic Peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM). Among several complications that contribute to reduce patient's quality of life and life expectancy diabetic neuropathy (DN) generalized or focal leads to an impaired life quality. The clinical symptoms of DPN range from pain and burning sensations, more at rest or at night; to hypoesthesia or paresthesia, and or numbness. Different types of peripheral neuropathy are observed in diabetes, axonal or demyelination (...) Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain Perineural Platelet-rich Plasma for Diabetic Neuropathy Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Perineural Platelet-rich Plasma

2018 Clinical Trials

396. Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing

Not Applicable Detailed Description: The subjects are being asked to consider participation in this research study. The purpose of this study is to see if incorporating mindfulness exercises prior to urodynamic studies (UDS) results in less pain, anxiety and discomfort. The participants will be guided through a mindfulness meditation exercise by a licensed professional. During this exercise participants will be asked to focus attention on breathing, physical sensations, and thoughts. This exercise will last (...) Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

397. Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies

in pain sensitivity [ Time Frame: change from baseline PPT at six weeks ] pressure pain threshold (PPT) was measured with digital algometer. Pressure pain threshold which identifies minimum levels increasing mechanical stimulus is gold standard method for measuring pain sensitivity. PPT was measured from cervical vertebrae's spinous process and muscle belly's. Algometer range was set 0 kgF to 12kgF. Higher values represent increased pressure sensation. Secondary Outcome Measures : change in Light (...) Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies Effect of Exercise and Manuel Therapy Methods on Pain, Posture, Daily Living in People With Cervical Pathologies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2018 Clinical Trials

398. Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy

from the first spray ] Discomfort will be scored as VAS on a scale of 1 to 10 (1 is least, 10 is most) Prevalence of adverse effects of pre-medication [ Time Frame: four minutes from the first spray ] allergy, burning pain, altered taste, chocking sensation, headache will be asked and recorded Pain due to procedure as VAS 1-10 [ Time Frame: At the end of the procedure ] Pain will be scored as VAS on a scale of 1 to 10 (1 is least, 10 is most) Ease of procedure as VAS 1-10 [ Time Frame: At the end (...) Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2018 Clinical Trials

399. The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain

The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2018 Clinical Trials

400. Lidocaine Jelly for Pain Control During Mohs Surgery

stage of surgery, an identical wound dressing will be placed on the operative site. Immediately prior to each subsequent stage of surgery, we will assess patients' pain sensation, and additional lidocaine/epinephrine will be injected if needed. After the surgical site is re-anesthetized, vital signs will be recorded and the Pain/Anxiety survey administered immediately prior to the first incision of that stage. Study Design Go to Layout table for study information Study Type : Interventional (...) Lidocaine Jelly for Pain Control During Mohs Surgery Lidocaine Jelly for Pain Control During Mohs Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lidocaine Jelly for Pain Control During Mohs Surgery

2018 Clinical Trials

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