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Pain Sensation

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281. Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. Full Text available with Trip Pro

Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. To conduct a randomized control trial to evaluate the feasibility and efficacy of virtual reality (VR) compared with standard of care (SOC) for reducing pain, anxiety, and improving satisfaction associated with blood draw in children ages 10-21 years.In total, 143 triads (patients, their caregiver, and the phlebotomist) were recruited (...) in outpatient phlebotomy at a pediatric hospital and randomized to receive either VR or SOC when undergoing routine blood draw. Patients and caregivers completed preprocedural and postprocedural standardized measures of pain, anxiety, and satisfaction, and phlebotomists reported about the patient's experience during the procedure.Findings showed that VR significantly reduced acute procedural pain and anxiety compared with SOC. A significant interaction between patient-reported anxiety sensitivity

2018 Journal of pediatric psychology Controlled trial quality: uncertain

282. Comparison Between Diclofenac and Ketorolac Ophthalmic Drops for Pain Management After Photorefractive Keratectomy: A Randomized Clinical Study. (Abstract)

diclofenac 0.1% drops and the other group was prescribed ketorolac 0.5% ophthalmic drops in both eyes every 6 hr on the first day and then, no NSAID was applied until the third day. No oral analgesic drug was used after surgery. Patients completed the Visual Analog Scale questionnaire to determine the degree of pain and ocular discomfort (tearing, foreign body sensation, blurred vision, and photophobia) on the first and the third day after surgery.Pain relief was achieved with both medications after (...) surgery, and there was no significant intergroup difference in the level of pain reduction at 24 and 72 hr postoperatively (P>0.05). The ketorolac group experienced less tearing and photophobia only at 24 hr postoperatively (P=0.01), and by 72 hr after surgery, the results were similar in two groups (P>0.05). There was no significant intergroup difference in terms of foreign body sensation or blurred vision on the first or third postoperative days (P>0.05).Both diclofenac and ketorolac are effective

2018 Eye & contact lens Controlled trial quality: uncertain

283. Pain relief after orthodontic archwire installation-a comparison between intervention with paracetamol and chewing gum: a randomized controlled trial. (Abstract)

versus chewing gum for pain alleviation and to investigate the frequency of bracket loss during the first day of fixed orthodontic treatment.Prospective randomized multicentre clinical trial.Sixty patients (28 boys and 32 girls), between 12 and 18 years of age were randomly allocated either to take paracetamol (31 patients) or to use chewing gum (29 patients). After one arch bonding and insertion of the initial archwire, the patients rated the sensation of pain on a visual analogue scale with the jaw (...) at rest and when biting after 6 hours (T1), at bedtime (T2), and the next morning (T3). Paracetamol (1000 mg) was taken 1 hour and chewing gum was used 10 minutes prior to pain rating at T2 and T3. A simple method of randomization was used in this study, and blinding of subjects and the operators to the type of intervention was not possible because of the nature of the treatments.There was no detectable difference in pain sensation between the groups at T1. At T2 and T3 the chewing gum group displayed

2018 European journal of orthodontics Controlled trial quality: uncertain

284. Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial. (Abstract)

orofacial pain were prospectively included and randomly assigned to single session of an active (iTBS) or sham (intermediate TBS; imTBS) stimulation delivered to the primary motor cortex (M1) contralateral to painful side. The primary outcome was pain relief assessed using a visual analogue scale (VAS) after stimulation and at the end of two-week follow- up. The secondary outcomes were changes in the quantitative sensory testing (QST). QST set the threshold for thermal and tactile (touch) sensation (...) Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial. Theta burst stimulation (TBS) is a modified form of high-frequency repetitive transcranial magnetic stimulation (rTMS) with promising effect in chronic pain. The aim of our double-blind, sham-controlled, parallel-group, randomized study was to assess an efficacy of intermittent TBS (iTBS) in the treatment of patients with chronic orofacial pain. Nineteen patients (twelve females) with chronic

2018 Physiological research Controlled trial quality: predicted high

285. Minocycline Prevents Muscular Pain Hypersensitivity and Cutaneous Allodynia Produced by Repeated Intramuscular Injections of Hypertonic Saline in Healthy Human Participants. (Abstract)

sensitivity in the skin overlying the anterior muscle compartment of both legs, quantitative sensory testing was used to measure the cutaneous thermal thresholds (cold sensation, cold pain, warm sensation, and heat pain) and a mild cooling stimulus was applied to assess the presence of cold allodynia. To induce ongoing hypersensitivity, repeated injections of HS were administered into the right tibialis anterior muscle at 48-hour intervals. In the final 2 sessions (days 9 and 14), only sensory assessments (...) Minocycline Prevents Muscular Pain Hypersensitivity and Cutaneous Allodynia Produced by Repeated Intramuscular Injections of Hypertonic Saline in Healthy Human Participants. Minocycline, a glial suppressor, prevents behavioral hypersensitivities in animal models of peripheral nerve injury. However, clinical trials of minocycline in human studies have produced mixed results. This study addressed 2 questions: can repeated injections of hypertonic saline (HS) in humans induce persistent

2018 The journal of pain : official journal of the American Pain Society Controlled trial quality: uncertain

286. Characteristics of Phantom Limb Pain Alleviated with Virtual Reality Rehabilitation. (Abstract)

characteristics" (r = 0.47, P = 0.02) but not "somatosensory-related pain characteristics" (r = 0.22, P = 0.17).The current findings indicate that VR rehabilitation may be particularly effective for PLP associated with distorted phantom limb movement and body representations (e.g., clamping, gnawing), compared with typical neuropathic sensations (e.g., shooting, burning, dysesthesia). (...) Characteristics of Phantom Limb Pain Alleviated with Virtual Reality Rehabilitation. Neurorehabilitation techniques using virtual reality (VR) systems have recently become widespread as a rehabilitation method for restoring phantom limb movement and alleviating phantom limb pain (PLP). However, analgesic effects have varied between studies, possibly because of differences in the characteristics of PLP between patients (e.g., cramping, burning, shooting). We aimed to reveal the relationship

2018 Pain Medicine

287. Psoriasis-Associated Cutaneous Pain: Etiology, Assessment, Impact, and Management. (Abstract)

Psoriasis-Associated Cutaneous Pain: Etiology, Assessment, Impact, and Management. Cutaneous pain, a very broad, subjective, and complex symptom, is prevalent in patients with psoriasis. It is prompted by neurogenic inflammation and augmented by physical and psychosocial stress. Many psoriasis patients are troubled by aching, burning, stinging, tenderness, cramping, and tingling in their skin. However, there lacks a thorough and verified metric that allows patients to adequately report (...) their unique skin pain experiences. Limited literature exists that aims to understand cutaneous pain in psoriasis patients; most studies focus on joint pain and generalized pain, and many do not specify the location of pain. This review explores and analyzes current literature on the etiology, assessment, burden, and management of skin pain in psoriasis patients. It emphasizes the significance of appropriately quantifying the skin pain experience in psoriasis and developing therapeutics that target

2018 Journal of Dermatological Treatment

288. Selecting Effective Combinations of Treatment for Low Back Pain

in the pathway to functional recovery, such as problems with the lumbar spinal structures or low back pain itself. In contrast, behavioral interventions for CLBP generally have effects not only on pain itself, but also work by mitigating the degree to which the sensation of low back pain impacts function, well-being, and quality of life. These represent later stages in the pathway to functional recovery from CLBP. Combining procedural and behavioral treatments may have great potential for achieving large (...) Selecting Effective Combinations of Treatment for Low Back Pain Selecting Effective Combinations of Treatment for Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Selecting Effective

2018 Clinical Trials

289. The Relationship Between Dizziness and Neck Pain

-regulated Device Product: No Keywords provided by Haukeland University Hospital: posturography quality of life pressure algometry cervicogenic dizziness Additional relevant MeSH terms: Layout table for MeSH terms Neck Pain Vertigo Dizziness Pain Neurologic Manifestations Signs and Symptoms Vestibular Diseases Labyrinth Diseases Ear Diseases Otorhinolaryngologic Diseases Nervous System Diseases Sensation Disorders (...) The Relationship Between Dizziness and Neck Pain The Relationship Between Dizziness and Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Relationship Between Dizziness and Neck Pain The safety

2018 Clinical Trials

290. Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN

-based interventions including body, emotions, sensations, thoughts, compassion, pain and stress management. Outcome Measures Go to Primary Outcome Measures : Change in mean score of the Brief Pain Inventory-Interference Scale (BPI-I) [ Time Frame: At enrollment prior to the program, 2 weeks post-program, and at a 3-month follow-up after the program ] The interference scale measures the degree to which pain interferes in the lives of participants in 7 domains: general activity, mood, walking ability (...) Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

291. Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease

of life Detailed Description: Central sensitization reduces the pain threshold in the pain pathways of the nervous system, causing pain sensation to be perceived with lower stimuli and often causing chronic pain. Central sensitization can be seen with many conditions such as neuropathic pain and sleep disorders, as well as with inflammatory diseases such as rheumatoid arthritis. There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance (...) Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

292. Ultrasonographic Parameters and Life Quality in Nocturnal Shoulder Pain

outpatient clinic and healthy volunteers Criteria Inclusion Criteria: Patients aged over 18 years diagnosed with rotator cuff tendinopathy Exclusion Criteria: Severe limitation and pain in head and neck movements Loss of strength Sensation and reflexes loss in the upper extremity Limitation in passive shoulder movements on physical examination Systemic rheumatic disease Diabetes mellitus Malignant disease Active infection Intraarticular injection Trauma Dementia History of surgery Bilateral should pain (...) Ultrasonographic Parameters and Life Quality in Nocturnal Shoulder Pain Ultrasonographic Parameters and Life Quality in Nocturnal Shoulder Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

293. Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain

, less than 6 months, six months or more) - obtained from participants interview) Sensation of tingling or numbness [ Time Frame: Baseline ] Dichotomous scale (yes/No) - (obtained from participants interview) Use of antidepressant [ Time Frame: Baseline ] Dichotomous scale (yes/No) - (obtained from participants interview) Use of anti-inflammatory drugs [ Time Frame: Baseline ] Dichotomous scale (yes/No) - (obtained from participants interview) Pain in sitting position [ Time Frame: Baseline ] Visual (...) Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

294. Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia

of 8% capsaicin topical patch or 0.1% capsaicin cream Outcome Measures Go to Primary Outcome Measures : Progression of Temporal Summation of Second Pain [ Time Frame: 2 hr ] A Peltier device (Pathway, Medoc) will be used to tap the skin surface with a 3 cm x 3 cm probe. The Peltier device will be used to provide very brief, repetitive, thermal stimuli (for approx. 1s) to the skin using computer controlled temperatures. Heat stimuli at intervals of 2.5 sec produce sensations of increasing pain (...) Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia Spinal and Supra-Spinal Pain Mechanisms in Patients With Fibromyalgia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Spinal and Supra

2018 Clinical Trials

295. Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.

or neurological disorder associated with altered pain sensation. a history of dysmenorrhea a contraindication for IUD use such as a gynaecological malignancy, pelvic inflammatory disease or undiagnosed abnormal vaginal bleeding. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (...) Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD. Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

296. Pain in Patients With Congenital Coagulopathies

of 42 items grouped in 7 scales of 6 items each, plus 2 items referring to the control exercised over pain and the ability to reduce it. Each item is scored according to a scale of 7 points (0 = never, 3 = sometimes, 6 = always). The scales included in this measuring instrument are: deviation of attention, reinterpretation of pain sensations, ignoring pain sensations, self-assertive coping, prayer and hope, catastrophism and increased level of activity. Perception of quality of life [ Time Frame (...) Pain in Patients With Congenital Coagulopathies Pain in Patients With Congenital Coagulopathies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Pain in Patients With Congenital Coagulopathies (He-PainSit

2018 Clinical Trials

297. Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting

Complications Pathologic Processes Pain Neurologic Manifestations Signs and Symptoms Somatosensory Disorders Sensation Disorders Nervous System Diseases Fentanyl Analgesics, Opioid Narcotics Central Nervous System Depressants Physiological Effects of Drugs Analgesics Sensory System Agents Peripheral Nervous System Agents Adjuvants, Anesthesia Anesthetics, Intravenous Anesthetics, General Anesthetics (...) Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

298. Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study

-5 multiple choice responses Non-painful phantom sensations (frequency and duration) [ Time Frame: Endpoints will be evaluated at baseline and post-treatment (Day 0), Days 1 and 7; and Months 1, 2, 3, 4, and 12 [same for crossover subjects with the exception of the 12-month time point] ] Sensations that feel to emanate from the missing limb, but are not described as pain Phantom limb pain (frequency and duration) [ Time Frame: Endpoints will be evaluated at baseline and post-treatment (Day 0 (...) Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

299. Effect of Smoking on Pain and Atherosclerosis in Patients With Rheumatoid Arthritis

by trained personnel, using an algometer. The algometer is placed bilaterally on the nail of the thumb and on the second metatarsophalangeal joint (MTP2), giving a total of four measured points. A progressively increasing pressure is applied with the algometer and the patients are carefully instructed to signal as soon as the pressure sensation turns into pain (not to withstand the pain) and the algometer is removed. The amount of applied force shown in kPa in the display is reported as the PPDT (...) Effect of Smoking on Pain and Atherosclerosis in Patients With Rheumatoid Arthritis Effect of Smoking on Pain and Atherosclerosis in Patients With Rheumatoid Arthritis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

300. Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy

significant foot deformity Skin condition that could alter peripheral sensations Previous surgery to the spine or lower extremity with residual symptoms of pain or difficulty with movement. Clinically significant arthropathy Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (...) Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy Dual Field PEMF Therapy in Lower Extremity Painful Diabetic Distal Symmetric Peripheral Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2018 Clinical Trials

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