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Pain Sensation

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281. Pain, please: Why would anybody volunteer to participate in pain research?

the likelihood of participating in research involving painful stimuli with pain-specific outcomes such as fear of pain and pain catastrophizing, as well as other outcomes that we thought might be relevant, such as sensation seeking, anxiety, and gender identity. In Study 2, we advertised two almost identical studies, one involving painful stimuli and the other one involving no painful stimuli. We then compared the people who signed up for the pain study with the people who signed up for the non-pain study (...) on the same outcomes as in the first study. What did we find? In total, 275 people participated in Study 1. Interestingly, more than half of the participants indicated that it is unlikely that they would ever participate in pain research. In the end, our analyses showed that participants who said that they would participate in pain research were older, had lower levels of pain-related fear, and higher sensation seeking. Eighty-seven participants took part in Study 2. In this study, we found that people

2018 Body in Mind blog

282. How do pain and working memory interact? Can we decrease pain by improving working memory?

for the tactile stimulus (Figure 2A). Non-painful (tactile) was determined as the first stimulus intensity that produced a tactile sensation under the electrodes (Figure 2B). Painful stimuli were 120% of the NFR threshold (Figure 2C). In both sessions, stimulus intensity was adjusted individually and the painful and tactile stimuli were always delivered with the same pair of electrodes. Figure 2. the nociceptive flexion reflex (NFR) measurement During both sessions, participants performed the same WM task (...) ) The between-session comparisons revealed no significant difference between anodal and sham tDCS. Our results showed that by enhancing WM performance, we can improve pain inhibition. The results imply that anodal tDCS can suppress pain indirectly by improving WM performance since pain inhibition by WM improvement was independent of descending inhibition of spinal nociception [7]. What were limitations of our study? It could be argued that participants may feel different sensations in the sham and anodal

2018 Body in Mind blog

283. Pain? Where?! Attentional bias for pain in the brain

psychologist, his timing could not have been better. Indeed, his accident proved to be the perfect illustration of what I was about to study. Every time he did his physio exercises, I noticed his response strongly depended on the movement he was about to execute. When the movement was pain-free, he would do it without hesitation. However, when the movement hurt, he would suddenly pay very close attention to the sensations in hand. Did the threat of pain steer my father’s attention? Unfortunately, based (...) pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS researcher Janet Bultitude find out by responding to her . The survey is aimed at people with CRPS, people with chronic pain conditions other than CRPS, and people without any chronic pain condition. The survey takes approximately 20 minutes and the responses are anonymous. Prof Paul Hodges on pain and altered

2018 Body in Mind blog

284. Explaining Pain for Acute Back Pain – reflections on Traeger et al. part 1

. Study recruitment is being conducted separately for both young people and parents. Please email if you would like to take part. Participants will be paid for their time. It’s impossible to slip your disc! Lorimer Moseley answering the question “What is the thing that annoys you most when we talk about back pain?” Online survey on bodily changes, sensations, and mood in people with chronic pain How do CRPS and other chronic pain conditions affect bodily functions, sensations, and mood? Help CRPS (...) Explaining Pain for Acute Back Pain – reflections on Traeger et al. part 1 Explaining Pain for Acute Back Pain - reflections on Traeger et al. part 1 Research into the role of the brain and mind in chronic pain Explaining Pain for Acute Back Pain – reflections on Traeger et al. part 1 November 27, 2018 by The PREVENT trial published recently in seems to have created a storm. If views and tweets and general social noise are your metric, then this one weighs in pretty well – over 15K views

2018 Body in Mind blog

285. Buffering local anaesthetics to reduce dental injection pain?

sensations during injection of anaesthetics. A potential cause of this is the acidic nature of the local anaesthetic solution. It has been suggested that alkalisation of local anaesthesia with buffering agents hey reduce pain and speed anaesthesia onsets period The aim of this review is to investigate the efficacy of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. Methods Searches were conducted in the Medline, Embase, Scopus and SCIELO databases (...) Buffering local anaesthetics to reduce dental injection pain? Buffering local anaesthetics to reduce dental injection pain? - National Elf Service Search National Elf Service Search National Elf Service » » » » Buffering local anaesthetics to reduce dental injection pain? Feb 28 2018 Posted by Local anaesthesia is essential in order to perform the wide range of dental procedures carried out daily in dental practices. While they help to control pain patients often report burning and stinging

2018 The Dental Elf

286. Knee pain - assessment

arthritis). Rapid onset (within 2 hours) of a large tense effusion following trauma suggests fracture, ligament rupture (usually the anterior cruciate ligament) or patellar dislocation. Slower onset (24-36 hours) of a mild to moderate effusion is consistent with meniscal injury or ligament sprain. Joint stiffness, and variation throughout the day. History of locking or giving way. Ripping or tearing sensations. Crepitus, snapping, or clicking are of limited value in identifying the cause of knee pain (...) pain Most commonly presents in teenage years or in young adulthood. Symptoms: Anterior knee pain, often behind the patella, that is: Diffuse and aching. Gradual in onset. Aggravated by ascending or descending stairs, squatting or sitting for prolonged periods. Sensation of 'giving way'. This is not true instability, which occurs in meniscal or ligamentous injury. Reported crepitus and/or stiffness. Signs: There are no features specific to patellofemoral pain. Range of movement is usually normal

2017 NICE Clinical Knowledge Summaries

287. Chest pain

. Signs — may be associated with paraesthesia or hyperaesthesia, but with no objective loss of sensation or muscle strength. To confirm a diagnosis of neck pain, see the scenario in the prodigy topic . Other causes of chest pain include: Psychogenic or non-specific chest pain History — the person has no identifiable risk factors for a physical cause of chest pain. Anxiety disorders are common, especially panic disorders. The episode is often preceded by a stressful event. Symptoms — chest pain (...) is usually in the left sub-mammary position (without radiation). The pain is sharp and continuous. The pain is aggravated by tiredness and stress, and may be associated with symptoms of hyperventilation (including tingling of the extremities) and palpitations. Herpes zoster Symptoms — prodrome (one to five days before the development of rash), abnormal sensation (for example burning, tingling, or itch) in the affected skin, there may also be headache, malaise, and photophobia. Signs — painful

2017 NICE Clinical Knowledge Summaries

288. Chronic Pelvic Pain, Initial Management

after the original tissue injury or exist in the absence of any such injury. Major changes are seen in both afferent and efferent nerve pathways in the central and peripheral nervous systems. Local factors, such as tumour necrosis factor alpha (TNF-) and chemokines, may change peripheral nerve function and/or stimulate normally quiescent fibres, resulting in altered sensation over a wider area than that originally affected. A persistent barrage of pain may lead to changes within the central nervous (...) system, which magnify the original signal. 7 Descending information from the central nervous system, possibly influenced by previous experiences and current circumstances, may modify pain perception and visceral function. Alteration in visceral sensation and function, provoked by a variety of neurological factors, has been termed ‘visceral hyperalgesia’. Nerve damage following surgery, trauma, inflammation, fibrosis or infection may play a part in this process. 8,9 Pain as a result of changes

2012 Royal College of Obstetricians and Gynaecologists

289. Mindfulness Training for Chronic Pain Management: A Review of the Clinical Evidence and Guidelines

Mindfulness Training for Chronic Pain Management: A Review of the Clinical Evidence and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources and a summary of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time (...) is given to CADTH. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Mindfulness Training for Chronic Pain Management: A Review of the Clinical Evidence and Guidelines DATE: 12 January 2012 CONTEXT AND POLICY ISSUES Chronic pain has been defined as persistent pain, which can be either

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

290. Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. Full Text available with Trip Pro

Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. To conduct a randomized control trial to evaluate the feasibility and efficacy of virtual reality (VR) compared with standard of care (SOC) for reducing pain, anxiety, and improving satisfaction associated with blood draw in children ages 10-21 years.In total, 143 triads (patients, their caregiver, and the phlebotomist) were recruited (...) in outpatient phlebotomy at a pediatric hospital and randomized to receive either VR or SOC when undergoing routine blood draw. Patients and caregivers completed preprocedural and postprocedural standardized measures of pain, anxiety, and satisfaction, and phlebotomists reported about the patient's experience during the procedure.Findings showed that VR significantly reduced acute procedural pain and anxiety compared with SOC. A significant interaction between patient-reported anxiety sensitivity

2018 Journal of pediatric psychology Controlled trial quality: uncertain

291. Comparison Between Diclofenac and Ketorolac Ophthalmic Drops for Pain Management After Photorefractive Keratectomy: A Randomized Clinical Study. (Abstract)

diclofenac 0.1% drops and the other group was prescribed ketorolac 0.5% ophthalmic drops in both eyes every 6 hr on the first day and then, no NSAID was applied until the third day. No oral analgesic drug was used after surgery. Patients completed the Visual Analog Scale questionnaire to determine the degree of pain and ocular discomfort (tearing, foreign body sensation, blurred vision, and photophobia) on the first and the third day after surgery.Pain relief was achieved with both medications after (...) surgery, and there was no significant intergroup difference in the level of pain reduction at 24 and 72 hr postoperatively (P>0.05). The ketorolac group experienced less tearing and photophobia only at 24 hr postoperatively (P=0.01), and by 72 hr after surgery, the results were similar in two groups (P>0.05). There was no significant intergroup difference in terms of foreign body sensation or blurred vision on the first or third postoperative days (P>0.05).Both diclofenac and ketorolac are effective

2018 Eye & contact lens Controlled trial quality: uncertain

292. Pain relief after orthodontic archwire installation-a comparison between intervention with paracetamol and chewing gum: a randomized controlled trial. (Abstract)

versus chewing gum for pain alleviation and to investigate the frequency of bracket loss during the first day of fixed orthodontic treatment.Prospective randomized multicentre clinical trial.Sixty patients (28 boys and 32 girls), between 12 and 18 years of age were randomly allocated either to take paracetamol (31 patients) or to use chewing gum (29 patients). After one arch bonding and insertion of the initial archwire, the patients rated the sensation of pain on a visual analogue scale with the jaw (...) at rest and when biting after 6 hours (T1), at bedtime (T2), and the next morning (T3). Paracetamol (1000 mg) was taken 1 hour and chewing gum was used 10 minutes prior to pain rating at T2 and T3. A simple method of randomization was used in this study, and blinding of subjects and the operators to the type of intervention was not possible because of the nature of the treatments.There was no detectable difference in pain sensation between the groups at T1. At T2 and T3 the chewing gum group displayed

2018 European journal of orthodontics Controlled trial quality: uncertain

293. Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial. (Abstract)

orofacial pain were prospectively included and randomly assigned to single session of an active (iTBS) or sham (intermediate TBS; imTBS) stimulation delivered to the primary motor cortex (M1) contralateral to painful side. The primary outcome was pain relief assessed using a visual analogue scale (VAS) after stimulation and at the end of two-week follow- up. The secondary outcomes were changes in the quantitative sensory testing (QST). QST set the threshold for thermal and tactile (touch) sensation (...) Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial. Theta burst stimulation (TBS) is a modified form of high-frequency repetitive transcranial magnetic stimulation (rTMS) with promising effect in chronic pain. The aim of our double-blind, sham-controlled, parallel-group, randomized study was to assess an efficacy of intermittent TBS (iTBS) in the treatment of patients with chronic orofacial pain. Nineteen patients (twelve females) with chronic

2018 Physiological research Controlled trial quality: predicted high

294. Minocycline Prevents Muscular Pain Hypersensitivity and Cutaneous Allodynia Produced by Repeated Intramuscular Injections of Hypertonic Saline in Healthy Human Participants. (Abstract)

sensitivity in the skin overlying the anterior muscle compartment of both legs, quantitative sensory testing was used to measure the cutaneous thermal thresholds (cold sensation, cold pain, warm sensation, and heat pain) and a mild cooling stimulus was applied to assess the presence of cold allodynia. To induce ongoing hypersensitivity, repeated injections of HS were administered into the right tibialis anterior muscle at 48-hour intervals. In the final 2 sessions (days 9 and 14), only sensory assessments (...) Minocycline Prevents Muscular Pain Hypersensitivity and Cutaneous Allodynia Produced by Repeated Intramuscular Injections of Hypertonic Saline in Healthy Human Participants. Minocycline, a glial suppressor, prevents behavioral hypersensitivities in animal models of peripheral nerve injury. However, clinical trials of minocycline in human studies have produced mixed results. This study addressed 2 questions: can repeated injections of hypertonic saline (HS) in humans induce persistent

2018 The journal of pain : official journal of the American Pain Society Controlled trial quality: uncertain

295. Characteristics of Phantom Limb Pain Alleviated with Virtual Reality Rehabilitation. (Abstract)

characteristics" (r = 0.47, P = 0.02) but not "somatosensory-related pain characteristics" (r = 0.22, P = 0.17).The current findings indicate that VR rehabilitation may be particularly effective for PLP associated with distorted phantom limb movement and body representations (e.g., clamping, gnawing), compared with typical neuropathic sensations (e.g., shooting, burning, dysesthesia). (...) Characteristics of Phantom Limb Pain Alleviated with Virtual Reality Rehabilitation. Neurorehabilitation techniques using virtual reality (VR) systems have recently become widespread as a rehabilitation method for restoring phantom limb movement and alleviating phantom limb pain (PLP). However, analgesic effects have varied between studies, possibly because of differences in the characteristics of PLP between patients (e.g., cramping, burning, shooting). We aimed to reveal the relationship

2018 Pain Medicine

296. Psoriasis-Associated Cutaneous Pain: Etiology, Assessment, Impact, and Management. (Abstract)

Psoriasis-Associated Cutaneous Pain: Etiology, Assessment, Impact, and Management. Cutaneous pain, a very broad, subjective, and complex symptom, is prevalent in patients with psoriasis. It is prompted by neurogenic inflammation and augmented by physical and psychosocial stress. Many psoriasis patients are troubled by aching, burning, stinging, tenderness, cramping, and tingling in their skin. However, there lacks a thorough and verified metric that allows patients to adequately report (...) their unique skin pain experiences. Limited literature exists that aims to understand cutaneous pain in psoriasis patients; most studies focus on joint pain and generalized pain, and many do not specify the location of pain. This review explores and analyzes current literature on the etiology, assessment, burden, and management of skin pain in psoriasis patients. It emphasizes the significance of appropriately quantifying the skin pain experience in psoriasis and developing therapeutics that target

2018 Journal of Dermatological Treatment

297. Selecting Effective Combinations of Treatment for Low Back Pain

in the pathway to functional recovery, such as problems with the lumbar spinal structures or low back pain itself. In contrast, behavioral interventions for CLBP generally have effects not only on pain itself, but also work by mitigating the degree to which the sensation of low back pain impacts function, well-being, and quality of life. These represent later stages in the pathway to functional recovery from CLBP. Combining procedural and behavioral treatments may have great potential for achieving large (...) Selecting Effective Combinations of Treatment for Low Back Pain Selecting Effective Combinations of Treatment for Low Back Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Selecting Effective

2018 Clinical Trials

298. The Relationship Between Dizziness and Neck Pain

-regulated Device Product: No Keywords provided by Haukeland University Hospital: posturography quality of life pressure algometry cervicogenic dizziness Additional relevant MeSH terms: Layout table for MeSH terms Neck Pain Vertigo Dizziness Pain Neurologic Manifestations Signs and Symptoms Vestibular Diseases Labyrinth Diseases Ear Diseases Otorhinolaryngologic Diseases Nervous System Diseases Sensation Disorders (...) The Relationship Between Dizziness and Neck Pain The Relationship Between Dizziness and Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Relationship Between Dizziness and Neck Pain The safety

2018 Clinical Trials

299. Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN

-based interventions including body, emotions, sensations, thoughts, compassion, pain and stress management. Outcome Measures Go to Primary Outcome Measures : Change in mean score of the Brief Pain Inventory-Interference Scale (BPI-I) [ Time Frame: At enrollment prior to the program, 2 weeks post-program, and at a 3-month follow-up after the program ] The interference scale measures the degree to which pain interferes in the lives of participants in 7 domains: general activity, mood, walking ability (...) Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

300. Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease

of life Detailed Description: Central sensitization reduces the pain threshold in the pain pathways of the nervous system, causing pain sensation to be perceived with lower stimuli and often causing chronic pain. Central sensitization can be seen with many conditions such as neuropathic pain and sleep disorders, as well as with inflammatory diseases such as rheumatoid arthritis. There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance (...) Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

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