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Pain Sensation

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201. Evaluation of Pressure Sense Threshold and Tactile Sensation After Lidocaine Iontophoresis Using Interferential Current

in mm. Pain and tactile thresholds were investigated using an electrical stimulator.The intensity was gradually increased to the extent that the participant reported a tingling sensation. The displayed intensity was considered as the tactile sense threshold. Then, the intensity was increased to the extent to be intolerable for the participant and this intensity was considered as the maximum pain threshold. The thresholds were recorded in milliampere. Lidocaine iontophoresis using interferential (...) Evaluation of Pressure Sense Threshold and Tactile Sensation After Lidocaine Iontophoresis Using Interferential Current Evaluation of Pressure Sense Threshold and Tactile Sensation After Lidocaine Iontophoresis Using Interferential Current - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2015 Clinical Trials

202. Altered thermal grill response and paradoxical heat sensations after topical capsaicin application. (Abstract)

thresholds, PHS, and warm, cold, and pain sensations to alternating cold (10°C) and warm (40°C) bars (the thermal grill [TG]) in the primary area (application site) after topical application with capsaicin and vehicle control (ethanol) on the volar forearms in randomized order in 80 healthy participants. As expected, capsaicin induced heat allodynia and hyperalgesia and decreased cold and cold pain sensation. In addition, we found that after capsaicin application, the TG caused less pain and burning than (...) the 40°C bars alone in contrast to the control side where the TG caused more pain and burning, consistent with the thermal grill illusion. In both situations, the pain intensity during the TG correlated inversely with both cold and warm pain thresholds but not with detection thresholds. Paradoxical heat sensation was only seen in 3 participants after control application but in 19 participants after capsaicin. Those with PHS after capsaicin application had higher detection thresholds to both cold

2015 Pain Controlled trial quality: uncertain

203. Placebo-induced somatic sensations: a multi-modal study of three different placebo interventions. Full Text available with Trip Pro

stimulation. The quality and intensity of evoked sensations were assessed using the McGill pain questionnaire and visual analogue scales (VAS), while subjects' sensation drawings processed by a geographic information system (GIS) were used to measure their spatial characteristics. We found that all three interventions are capable of producing robust sensations most frequently described as "tingling" and "warm" that can reach consider-able spatial extent (≤ 205 mm²) and intensity (≤ 80/100 VAS). Sensations (...) from placebo stimulation were often referred to areas remote from the stimulation site and exhibit considerable similarity with referred pain. Interestingly, there was considerable similarity of qualitative features as well as spatial patterns across subjects and placebos. However, placebo laser stimulation elicited significantly stronger and more widespread sensations than placebo irritant solution. Finally, novelty seeking, a character trait assessed by the Temperament and Character Inventory

2015 PloS one

204. Surface electrical stimulation to evoke referred sensation. Full Text available with Trip Pro

Surface electrical stimulation to evoke referred sensation. Surface electrical stimulation (SES) is being investigated as a noninvasive method to evoke natural sensations distal to electrode location. This may improve treatment for phantom limb pain as well as provide an alternative method to deliver sensory feedback. The median and/or ulnar nerves of 35 subjects were stimulated at the elbow using surface electrodes. Strength-duration curves of hand sensation were found for each subject. All (...) subjects experienced sensation in their hand, which was mostly described as a paresthesia-like sensation. The rheobase and chronaxie values were found to be lower for the median nerve than the ulnar nerve, with no significant difference between sexes. Repeated sessions with the same subject resulted in sufficient variability to suggest that recalculating the strength-duration curve for each electrode placement is necessary. Most of the recruitment curves in this study were generated with 28 to 36 data

2015 Journal of rehabilitation research and development Controlled trial quality: uncertain

205. Comparing Ways to Freeze the Nerve That Provides Thigh Sensation

Information provided by (Responsible Party): Gaurav Gupta, Canadian Forces Health Services Centre Ottawa Study Details Study Description Go to Brief Summary: Background The sensation on the outside of portion of our thighs is provided by a nerve called the lateral femoral cutaneous nerve (LFCN). The investigators can inject freezing around the nerve to reduce the feeling around the thigh (i.e. anesthesia). Anesthesia, or freezing, of the lateral femoral cutaneous nerve can reduce pain for patients having (...) Comparing Ways to Freeze the Nerve That Provides Thigh Sensation Comparing Ways to Freeze the Nerve That Provides Thigh Sensation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Comparing Ways to Freeze

2015 Clinical Trials

206. PK2/PKR1 Signaling Regulates Bladder Function and Sensation in Rats with Cyclophosphamide-Induced Cystitis Full Text available with Trip Pro

time points (4 h, 48 h, and 8 d) after CYP treatment. Combining a nonselective antagonist of prokineticin receptors (PKRA), we further evaluated the regulatory role of PK2 in modulating bladder function and visceral pain sensation via conscious cystometry and pain behavioral scoring. PK2 and prokineticin receptor 1 (PKR1), but not prokineticin receptor 2, were detected in normal and upregulated in CYP-treated rat bladders at several levels. Immunohistochemistry staining localized PKR1 primarily (...) in the urothelium. Blocking PKRs with PKRA showed no effect on micturition reflex activity and bladder sensation in control rats while it increased the voiding volume, prolonged voiding interval, and ameliorated visceral hyperalgesia in rats suffering from CYP-induced cystitis. In conclusion, PK2/PKR1 signaling pathway contributes to the modulation of inflammation-mediated voiding dysfunction and spontaneous visceral pain. Local blockade of PKRs may represent a novel and promising therapeutic strategy

2015 Mediators of inflammation

207. A Pilot Study of the Effect of Daikenchuto on Rectal Sensation in Patients with Irritable Bowel Syndrome. Full Text available with Trip Pro

and postprandial), bowel pattern, abdominal pain (average and worst severity) and bloating scores, IBS quality of life and safety profile.Rectal sensation ratings post-treatment were significantly associated with baseline (pre-treatment) ratings and with level of anxiety or stress recorded at the time of the sensation testing. There were no effects of TU-100 treatment on rectal sensation ratings, sensation thresholds, rectal fasting or postprandial tone, rectal compliance, bowel function, abdominal pain (...) A Pilot Study of the Effect of Daikenchuto on Rectal Sensation in Patients with Irritable Bowel Syndrome. Daikenchuto (TU 100), a botanical agent that modulates gastrointestinal nerves, is used in the treatment of motility and functional disorders. Our aim was to study the effects of TU-100 on rectal compliance and sensation in patients with irritable bowel syndrome (IBS).In 20 patients per treatment arm, we conducted a single-center, randomized, parallel-group, double-blind, placebo-controlled

2015 Journal of neurogastroenterology and motility Controlled trial quality: uncertain

208. Neck pain - acute torticollis

of cancer — in these people, aetiology of pain should be assumed to be cancer, until it is excluded. Presence of fever — in these people, neck pain should be assumed to be secondary to an infection until proven otherwise. Assess the appearance of the neck and the range of motion. Palpate the neck for tenderness. Evaluate for evidence of neurological involvement (for example, decrease in sensation, or strength, or abnormal reflexes). Inspect the skin — for example, for papulovesicular rash in a prodromal (...) Neck pain - acute torticollis Neck pain - acute torticollis - NICE CKS Share Neck pain - acute torticollis: Summary Torticollis, or wry neck, is a painful neck. Acute torticollis (less than six weeks duration) is thought to be due to minor local musculoskeletal irritation causing pain and spasm in neck muscles. The cause of torticollis is often not known, but it may be due to issues with posture — for example, poor positioning at a computer screen, inappropriate seating, sleeping without

2018 NICE Clinical Knowledge Summaries

209. Neck pain - cervical radiculopathy

and disease is very difficult to define [ ]. Signs and symptoms What are the signs and symptoms of cervical radiculopathy? Symptoms of cervical radiculopathy include: Pain in the neck, shoulder and/or arm that approximates to that of a dermatome. It is usually unilateral, but may be bilateral. The pain may be severe enough to wake the person at night. Sensory symptoms, such as absent or altered sensation (for example, shooting pains, numbness, and hyperaesthesia). Sensory symptoms are more common than (...) persistent or debilitating pain combined with loss of power or sensation [ ]. Prescribing information Prescribing information For prescribing information on nonsteroidal anti-inflammatory drugs (NSAIDs), paracetamol, and codeine, see the CKS topics on and . For further information on prescribing amitriptyline, pregabalin and gabapentin, see the CKS topic on . Supporting evidence Supporting evidence This CKS topic is largely based on the British Medical Journal (BMJ) best practice guide Assessment of neck

2018 NICE Clinical Knowledge Summaries

210. Back pain - low (without radiculopathy)

or swelling of the back. Perform a neurological examination looking for loss of sensation, changes to reflexes, limitation of range of movement including straight leg raising, tenderness, fever and loss of anal tone. Assess for the presence of that may suggest a serious underlying cause, such as: Cauda equina syndrome. Cancer of the spine. Spinal fracture due to trauma or osteoporotic collapse. Spinal infection. Be aware that low back pain can be caused by intra-abdominal p athol ogy, including (...) Back pain - low (without radiculopathy) Back pain - low (without radiculopathy) - NICE CKS Share Back pain - low (without radiculopathy): Summary Low back pain affects the lumbosacral area of the back, between the bottom of the ribs and the top of the legs. It affects around one third of the adult population each month. In most people, low back pain is non-specific and serious specific causes are rare. Complications include: Development of chronicity and depression. Disability and loss

2018 NICE Clinical Knowledge Summaries

211. Neck pain - non-specific

. Assess the appearance of the neck and the range of motion. Palpate the neck for tenderness. Inspect the skin — for example, for papulovesicular rash, petechiae or purpura. Evaluate for evidence of neurological involvement (for example, decrease in sensation, or strength, or abnormal reflexes). A combination of tests can be used to help identify cervical radiculopathy, including the Spurling test. For more information, see the CKS topic on . Consider examining for Kernig's sign (painful/resisted (...) , into the shoulder, or across the scapulae. Pain associated with paraesthesia or hyperaesthesia, but with no objective loss of sensation or muscle strength. Positional asymmetry, limited range of movements often asymmetrically. Tenderness in intervertebral joints and/or hypertonic muscles that may be palpable as nodules or tender bands. Red flags What signs and symptoms may indicate a more serious pathology? Signs and symptoms that may indicate a more serious pathology (for example, spinal cord compression

2018 NICE Clinical Knowledge Summaries

212. Neck pain - whiplash injury

, regardless of pain, do not require cervical spine radiography. Suspect a serious neck injury if the person cannot laterally rotate the neck more than 45 degrees. Assess disability using the Neck Disability Index (NDI). Evaluate for evidence of neurological involvement (for example, decrease in sensation, or strength, or abnormal reflexes). For more information, see the section on in the CKS topic on . Consider examining for Kernig's sign (painful/resisted extension of leg bent at hip and knee (...) of objective physical signs. II — neck pain and associated symptoms in the presence of objective physical signs and without evidence of neurological involvement. III — neck pain and associated symptoms with evidence of neurological involvement including decreased or absent reflexes, decreased or limited sensation, or muscular weakness. IV — neck pain and associated symptoms with evidence of fracture or dislocation. [ ] Basis for recommendation Basis for recommendation These recommendations are based

2018 NICE Clinical Knowledge Summaries

213. How can we assess the intensity of non-painful events as well as painful events? Full Text available with Trip Pro

be frustrating. At the same time, the researcher loses potentially valuable information by restricting the participant’s response options. What about putting both non-painful and painful experiences onto a single scale? OK sure, it would violate the age-old traditions of psychophysiology, but it could be useful. We tentatively developed this ‘Sensation and Pain Rating Scale’ (SPARS) (Figure 1). Figure 1: The Sensation and Pain Rating Scale (SPARS) We piloted it to determine whether people intuitively (...) presented separately. We chose a conventional NRS (0 = no pain; 100 = worst pain you can imagine) to represent the ‘painful’ end of the SPARS, and an invented ‘Sensation Rating Scale’ (SRS) (0 = no sensation; 100 = pain) to represent the non-painful end of the SPARS. In this Experiment 2, our participants rated a range of intensities of laser stimulation. In each block, they used only the SPARS, only the NRS, or only the SRS. We asked participants a whole heap of questions and we [1] Here’s what we

2019 Body in Mind blog

214. Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol. (Abstract)

. A study conducted by Honarmand, concluded that the addition of ondansetron to lidocaine for IVRA reduced intraoperative and postoperative analgesic use.Tourniquet pain, which is described as a dull and aching pain sensation, is caused by the nerve compression from the tourniquet. Neuropathic pain produced by nerve compression plays an important role in the etiology of this discomfort. Tourniquet pain is thought to be mediated by impulse propagation via small, unmyelinated, slow-conducting C fibers (...) Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol. The objective of this quantitative systematic review is to determine the effects of ondansetron as an adjunct to lidocaine on the tourniquet pain and postoperative pain of American Society of Anesthesiologists (ASA) class 1 or 2 adult patients undergoing elective hand surgery with intravenous

2015 JBI database of systematic reviews and implementation reports

215. Hand Pain and Sensory Deficits: Carpal Tunnel Syndrome

: Clinical Practice Guidelines ICF body structure code Structure of the nervous system other specified s198 Structure of hand s7302 Muscles of the hand s73022 ICF body function codes Sleep functions b134 Maintenance of sleep cycle b1342 Proprioceptive function b260 T ouch function b265 Sensory functions related to temperature and other stimuli b270 Sensitivity to vibration b2701 Sensitivity to pressure b2702 Sensation of pain b280 Radiating pain in a segment or region b2804 Pain in upper limb b28014 (...) Hand Pain and Sensory Deficits: Carpal Tunnel Syndrome Clinical Practice Guidelines MIA ERICKSON, PT , EdD • MARSHA LAWRENCE, PT , DPT • CAROLINE W. STEGINK JANSEN, PT , PhD DIANE COKER, PT , DPT • PETER AMADIO, MD • CARLA CLEARY, PT , DPT Hand Pain and Sensory Deficits: Carpal Tunnel Syndrome Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health From the Academy of Hand and Upper Extremity Physical Therapy and the Academy of Orthopaedic

2019 The Orthopaedic Section of the American Physical Therapy Association (APTA), Inc.

216. Nonpharmacological Management of Procedure-Related Pain in the Breastfeeding Infant

undergoing heel prick found general- ized cortical activation in breastfed infants that was lacking in infants receiving glucose for analgesia. It was theorized that breastfeeding’s multisensory expe- rience helped to overwhelm the pain sensation. 22 Skin-to-skin contact 1. Coordinating a breastfeeding session with the timing of the procedure is best, but, if this is not possible, skin-to-skin contact with the mother or other caregiver can comfort infants undergoing a procedure such as a heel lance (IA (...) Nonpharmacological Management of Procedure-Related Pain in the Breastfeeding Infant ABM Protocol ABM Clinical Protocol #23: Nonpharmacological Management of Procedure-Related Pain in the Breastfeeding Infant, Revised 2016 Sarah Reece-Stremtan, 1 Larry Gray, 2 and the Academy of Breastfeeding Medicine Acentralgoalof TheAcademyofBreastfeedingMedicineisthedevelopmentofclinicalprotocolsformanaging common medical problems that may impact breastfeeding success. These protocols serve only

2016 Academy of Breastfeeding Medicine

217. Persistent Pain with Breastfeeding

for vasospasm of the nipple. Allodynia/functional pain Allodynia is de?ned as sensation of pain in response to a stimulus,suchaslighttouch,whichwouldnotnormallyelicit pain.Breastallodyniacanoccurinisolationorinthecontext of other pain disorders, such as irritable bowel syndrome, ?bromyalgia, interstitial cystitis, migraines, temporoman- dibular joint disorders (TMJ), and pain with intercourse. Taking a careful history to assess for other pain disorders is important for informing treatment (...) Persistent Pain with Breastfeeding ABM Protocol ABM Clinical Protocol #26: Persistent Pain with Breastfeeding Pamela Berens, 1 Anne Eglash, 2 Michele Malloy, 2 Alison M. Steube, 3,4 and the Academy of Breastfeeding Medicine A central goal of The Academy of Breastfeeding Medicine is the development of clinical protocols for man- aging common medical problems that may impact breastfeeding success. These protocols serve only as guidelines for the care of breastfeeding mothers and infants and do

2016 Academy of Breastfeeding Medicine

218. Does attention bias modification training impact on task performance in the context of pain: An experimental study in healthy participants. Full Text available with Trip Pro

training -using a visual probe paradigm with idiosyncratic pain words- on cold pressor test (CPT) pain experience and task interference by pain. Fifty-eight healthy volunteers were randomly assigned to an ABM training group (N = 28; attending away from pain) and a sham training group (N = 30; no training direction). At pre-training, participants performed a baseline Random-Interval-Repetition (RIR) task and the CPT. Participants reported on sensations they experienced during the baseline CPT. Relevant (...) Does attention bias modification training impact on task performance in the context of pain: An experimental study in healthy participants. Attention has been theorized to play a key role in the experience of pain and associated task interference. Training attention away from pain via attention bias modification (ABM) training techniques has been proposed to improve pain-related outcomes, but evidence is inconsistent. In an experimental study, we investigated the impact of a single session ABM

2018 PLoS ONE Controlled trial quality: uncertain

219. Thoracic Trauma, Blunt, Pain Management of

Thoracic Trauma, Blunt, Pain Management of Thoracic Trauma, Blunt, Pain Management of - Practice Management Guideline Search » Thoracic Trauma, Blunt, Pain Management of Published 2016 Citation: Authors Galvagno, Samuel Michael Jr DO, PhD; Smith, Charles E. MD; Varon, Albert J. MD, MHPE; Hasenboehler, Erik A. MD; Sultan, Shahnaz MD, MHSc; Shaefer, Gregory DO; To, Kathleen B. MD; Fox, Adam D. DO, DPM; Alley, Darrell E.R. MD; Ditillo, Michael DO; Joseph, Bellal A. MD; Robinson, Bryce R.H. MD, MS (...) with significant morbidity. [1–3] In particular, rib fractures occur in up to 10% of hospitalized trauma patients and may be associated with a mortality of 3% to 13%. [1][4][5] Injuries caused by blunt thoracic trauma are frequently associated with pulmonary complications such as pneumonia and severe pain, prolonging both hospital and intensive care unit (ICU) stay and significantly increasing healthcare costs, especially in elderly patients. [6][7] Pain is acknowledged as a contributing element for much

2016 Eastern Association for the Surgery of Trauma

220. CRACKCast E003 – Pain Management

root ganglion (visceral, muscle, bone, cutaneous) and CROSSES over before ascending the brainstem at which point it enters the thalamus and is interpreted by the cortex. R emember that position and vibration sensation remain IPSILATERAL. pain modulation involves: nociceptors, inflammatory mediators (substance P) AND can lead to chronic central and cognitive sensitization which is affected by opiates at the Mu receptors and norepinephrine as well as emotions, experience, past exposure to pain (...) CRACKCast E003 – Pain Management CRACKCast E003 - Pain Management - CanadiEM CRACKCast E003 – Pain Management In , by Chris Lipp September 1, 2016 This episode of CRACKCast cover’s Rosen’s Chapter 003, Pain Management. This is an essential toolset to master, as this is a key thing that emergency physicians deal with everyday, for more reading on the subject check out the Rosen’s chapter itself. Show Notes – 1. Describe the steps in the afferent pain pathway A sensory input enters the dorsal

2016 CandiEM

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