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1. Overdiagnosis

Overdiagnosis Top results for overdiagnosis - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for overdiagnosis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

2. Primary care: Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities Full Text available with Trip Pro

Primary care: Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities | BMJ Evidence-Based Medicine Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities Article Text Editorial Primary care Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities Free Carl Heneghan , Kamal R Mahtani Statistics from Altmetric.com In their paper, Ray Moynihan and colleagues analyse the problems of disease thresholds

2019 Evidence-Based Medicine

3. Primary care: Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics Full Text available with Trip Pro

Primary care: Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics | BMJ Evidence-Based Medicine Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? You are here Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics Article Text EBM analysis Primary care Overdiagnosis paradigm: not suitable for decreasing the overuse of antibiotics Gloria Cordoba , Carl Llor . Statistics from Altmetric.com Introduction Unnecessary and excessive use of antibiotics is the main driver of antimicrobial resistance. The prospect of patients dying from common infections caused

2019 Evidence-Based Medicine

4. Overdiagnosis: what it is and what it isn?t Full Text available with Trip Pro

Overdiagnosis: what it is and what it isn?t Overdiagnosis: what it is and what it isn’t | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Overdiagnosis: what it is and what it isn’t Article Text Editorial Overdiagnosis: what it is and what it isn’t Free John Brodersen , , Lisa M Schwartz , Carl Heneghan , Jack William O’Sullivan , Jeffrey K Aronson , Steven Woloshin Statistics from Altmetric.com Why then, can one desire too much

2018 Evidence-Based Medicine

5. Response to Brodersen et al’ s ‘Overdiagnosis: what it is and what it isn’t’ Full Text available with Trip Pro

Response to Brodersen et al’ s ‘Overdiagnosis: what it is and what it isn’t’ Response to Brodersen et al’ s ‘Overdiagnosis: what it is and what it isn’t’ | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Response to Brodersen et al’ s ‘Overdiagnosis: what it is and what it isn’t’ Article Text Letter Response to Brodersen et al’ s ‘Overdiagnosis: what it is and what it isn ’ t ’ Wendy A Rogers 1 , 2 , Yishai Mintzker 3 Statistics from

2018 Evidence-Based Medicine

6. Lifetime risk of prostate cancer overdiagnosis in Australia: quantifying the risk of overdiagnosis associated with prostate cancer screening in Australia using a novel lifetime risk approach. Full Text available with Trip Pro

Lifetime risk of prostate cancer overdiagnosis in Australia: quantifying the risk of overdiagnosis associated with prostate cancer screening in Australia using a novel lifetime risk approach. To quantify the risk of overdiagnosis associated with prostate cancer screening in Australia using a novel lifetime risk approach.Modelling and validation of the lifetime risk method using publicly available population data.Opportunistic screening for prostate cancer in the Australian population.Australian (...) male population (1982-2012).Prostate-specific antigen testing for prostate cancer screening.Primary: lifetime risk of overdiagnosis in 2012 (excess lifetime cancer risk adjusted for changing competing mortality); Secondary: lifetime risk of prostate cancer diagnosis (unadjusted and adjusted for competing mortality); Excess lifetime risk of prostate cancer diagnosis (for all years subsequent to 1982).The lifetime risk of being diagnosed with prostate cancer increased from 6.1% in 1982 (1 in 17

2019 BMJ open

7. On the Social Construction of Overdiagnosis: Comment on "Medicalisation and Overdiagnosis: What Society Does to Medicine" Full Text available with Trip Pro

On the Social Construction of Overdiagnosis: Comment on "Medicalisation and Overdiagnosis: What Society Does to Medicine" In an interesting article Wieteke van Dijk and colleagues argue that societal developments and values influence the practice of medicine, and thus can result in both medicalisation and overdiagnosis. They provide a convincing argument that overdiagnosis emerges in a social context and that it has socially constructed implications. However, they fail to show (...) that overdiagnosis per se is socially constructed and how this construction occurs. Moreover, the authors discuss overdiagnosis on a micro level without acknowledging that overdiagnosis cannot be observed in individuals "in the doctor's office." We cannot tell whether a diagnosed person is overdiagnosed or not. This is the core of the problem. Despite these shortcomings, Wieteke van Dijk and her colleagues are certainly on to something important, and they should be encouraged to elaborate their perspective. We

2017 International journal of health policy and management

8. Overdiagnosis: An Important Issue That Demands Rigour and Precision: Comment on "Medicalisation and Overdiagnosis: What Society Does to Medicine" Full Text available with Trip Pro

Overdiagnosis: An Important Issue That Demands Rigour and Precision: Comment on "Medicalisation and Overdiagnosis: What Society Does to Medicine" Van Dijk and colleagues present three cases to illustrate and discuss the relationship between medicalisation and overdiagnosis. In this commentary, I consider each of the case studies in turn, and in doing so emphasise two main points. The first is that it is not possible to assess whether overdiagnosis is occurring based solely on incidence rates (...) : it is necessary also to have data about the benefits and harms that are produced by diagnosis. The second is that much is at stake in discussions of overdiagnosis in particular, and that it is critical that work in this area is conceptually rigorous, well-reasoned, and empirically sound. van Dijk and colleagues remind us that overdiagnosis and medicalisation are not just matters for individual patients and their clinicians: they also concern health systems, and society and citizens more broadly.© 2017

2017 International journal of health policy and management

9. Recent incidence and surgery trends for prostate cancer: Towards an attenuation of overdiagnosis and overtreatment? Full Text available with Trip Pro

Recent incidence and surgery trends for prostate cancer: Towards an attenuation of overdiagnosis and overtreatment? Screening for prostate cancer is frequent in high-income countries, including Switzerland. Notably due to overdiagnosis and overtreatment, various organisations have recently recommended against routine screening, potentially having an impact on incidence, mortality, and surgery rates. Our aim was therefore to examine whether secular trends in the incidence and mortality (...) and prostatectomy observed in Switzerland among men younger than 70 years have concomitantly leveled off around 2002/2003. Given the decreasing mortality, these trends may reflect recent changes in screening and clinical workup practices, with a possible attenuation of overdiagnosis and overtreatment.

2019 PLoS ONE

10. The potential for overdiagnosis and underdiagnosis because of blood pressure variability: a comparison of the 2017 ACC/AHA, 2018 ESC/ESH and 2019 NICE hypertension guidelines. Full Text available with Trip Pro

The potential for overdiagnosis and underdiagnosis because of blood pressure variability: a comparison of the 2017 ACC/AHA, 2018 ESC/ESH and 2019 NICE hypertension guidelines. To estimate the extent that BP measurement variability may drive over- and underdiagnosis of 'hypertension' when measurements are made according to current guidelines.Using data from the National Health and Nutrition Examination Survey and empirical estimates of within-person variability, we simulated annual SBP (...) are at risk of overdiagnosis under the 2017 American College of Cardiology guideline than the other two guidelines, even if nonoffice measurements are used. Making clinical decisions about cardiovascular prediction based primarily on absolute risk, minimizes the impact of blood pressure variability on overdiagnosis.

2020 Journal of Hypertension

11. Thyroid Cancer Incidence in India Between 2006 and 2014 and Impact of Overdiagnosis. (Abstract)

Thyroid Cancer Incidence in India Between 2006 and 2014 and Impact of Overdiagnosis. Increases of thyroid cancer (TC) incidence emerged in the past several decades in several countries. This study aimed to estimate time trends of TC incidence in India and the proportion of TC cases potentially attributable to overdiagnosis by sex, age, and area.TC cases aged 0 to 74 years reported to Indian cancer registries during 2006 through 2014 were included. Age-standardized incidence rates (ASR) and TC (...) overdiagnosis were estimated by sex, period, age, and area.Between 2006 to 2008 and 2012 to 2014, the ASRs for TC in India increased from 2.5 to 3.5/100,000 women (+37%) and from 1.0 to 1.3/100,000 men (+27%). However, up to a 10-fold difference was found among regions in both sexes. Highest ASRs emerged in Thiruvananthapuram (14.6/100,000 women and 4.1/100,000 men in 2012-2014), with 93% increase in women and 64% in men compared with 2006 to 2008. No evidence of overdiagnosis was found in Indian men

2020 Journal of Clinical Endocrinology and Metabolism

12. How do patients and the public understand overtesting and overdiagnosis? A protocol for a thematic meta-synthesis of qualitative research. Full Text available with Trip Pro

How do patients and the public understand overtesting and overdiagnosis? A protocol for a thematic meta-synthesis of qualitative research. Examining patient and public understanding of overtesting and overdiagnosis (OverTD) is vital for reducing the burden of OverTD. Studies from disparate contexts, disciplines and focusing on disparate healthcare issues have examined patient and public understanding of OverTD. A synthesis is needed to bring this literature together, examine common themes

2020 BMJ open

13. The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment. (Abstract)

The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment. There has been a tremendous evolution in our thinking about cancer since the 1880s. Breast cancer is a particularly good example to evaluate the progress that has been made and the new challenges that have arisen due to screening that inadvertently identifies indolent lesions. The degree to which overdiagnosis is a problem depends on the reservoir of indolent disease, the disease (...) characterization, diagnostics, and therapeutics can inform our approach to screening, early detection, and prevention. Overdiagnosis can be mitigated by developing diagnostics to identify indolent disease, incorporating biology and risk assessment in screening strategies, changing the pathology rules for tumor classification, and refining the way we classify precancerous lesions. The more the patterns of cancers can be seen across other cancers, the more it is clear that our approach should transcend organ

2020 Cancer Epidemiology & Biomarkers and Prevention

14. Trends in lung cancer risk and screening eligibility affect overdiagnosis estimates. Full Text available with Trip Pro

Trends in lung cancer risk and screening eligibility affect overdiagnosis estimates. The degree of overdiagnosis due to lung cancer screening in the general US population remains unknown. Estimates may be influenced by the method used and by decreasing smoking trends, which reduce lung cancer risk and screening eligibility over time. Therefore, we aimed to estimate the degree of overdiagnosis due to lung cancer screening in the general US population, using three distinct methods.The MISCAN-Lung (...) model was used to project lung cancer incidence and overdiagnosis in the general US population between 2018-2040, assuming perfect adherence to the United States Preventive Task Force recommendations. MISCAN-Lung was calibrated to the NLST and PLCO trials and incorporates birth-cohort-specific smoking trends and life expectancies. We estimated overdiagnosis using the cumulative excess-incidence approach, the annual excess-incidence approach, and the microsimulation approach.Using the cumulative

2020 Lung Cancer

15. Overdiagnosis in primary care: framing the problem and finding solutions. Full Text available with Trip Pro

Overdiagnosis in primary care: framing the problem and finding solutions. Overdiagnosis, is defined as the diagnosis of a condition that, if unrecognized, would not cause symptoms or harm a patient during his or her lifetime, and it is increasingly acknowledged as a consequence of screening for cancer and other conditions. Because preventive care is a crucial component of primary care, which is delivered to the broad population, overdiagnosis in primary care is an important problem from (...) a public health perspective and has far reaching implications. The scope of overdiagnosis as a result of services delivered in primary care is unclear, though overdiagnosis of indolent breast, prostate, thyroid, and lung cancers is well described and overdiagnosis of chronic kidney disease, depression, and attention-deficit/hyperactivity disorder is also recognized. However, overdiagnosis is a known consequence of all screening and can be assumed to occur in many more clinical contexts. Overdiagnosis

2018 BMJ

16. Defining, Estimating, and Communicating Overdiagnosis in Cancer Screening. (Abstract)

Defining, Estimating, and Communicating Overdiagnosis in Cancer Screening. The toll of inadequate health care is well-substantiated, but recognition is mounting that "too much" is also possible. Overdiagnosis represents one harm of too much medicine, but the concept can be confusing: It is often conflated with related harms (such as overtreatment, misclassification, false-positive results, and overdetection) and is difficult to measure because it cannot be directly observed. Because the U.S (...) . Preventive Services Task Force (USPSTF) issues screening recommendations aimed largely at healthy persons, it has a particular interest in understanding harms related to screening, especially but not limited to overdiagnosis. In support of the USPSTF, the authors summarize the knowledge and provide guidance on defining, estimating, and communicating overdiagnosis in cancer screening. To improve consistency, thinking, and reporting about overdiagnosis, they suggest a specific definition. The authors

2018 Annals of Internal Medicine

17. Rising Thyroid Cancer Incidence in Southern India: An Epidemic of Overdiagnosis? Full Text available with Trip Pro

Rising Thyroid Cancer Incidence in Southern India: An Epidemic of Overdiagnosis? Thyroid cancer incidence is rising in high-income countries. This increase in disease burden is attributed to the phenomenon of overdiagnosis.We aimed to investigate trends in thyroid cancer rates in India, focusing on the state of Kerala in southern India, which has reported a high incidence of the disease.Population-based study using data from the National Cancer Registry Program.We used data from the Population (...) to overdiagnosis.

2017 Journal of the Endocrine Society

18. Higher breast cancer prevalence associated with higher socioeconomic status in the South Korean population; Has it resulted from overdiagnosis? Full Text available with Trip Pro

Higher breast cancer prevalence associated with higher socioeconomic status in the South Korean population; Has it resulted from overdiagnosis? Recently, breast cancer prevalence has increased in South Korea. In this study, we investigated the correlation between breast cancer prevalence and socioeconomic status. This study enrolled 27,331 people who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) IV-VI (2007-2015). In addition, we obtained data from

2018 PLoS ONE

19. Observational study: US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis

Observational study: US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your (...) of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis Article Text Therapeutics/Prevention Observational study US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis Rebecca A Hubbard Statistics from Altmetric.com Commentary on: Harding C , Pompei F , Burmistrov D , et al . Breast Cancer Screening, Incidence

2015 Evidence-Based Medicine

20. Back to basics: overdiagnosis is about unwarranted diagnosis. Full Text available with Trip Pro

Back to basics: overdiagnosis is about unwarranted diagnosis. Epidemiological studies of overdiagnosis are challenged by unclear definitions and absence of unified measures. This spurs great controversies. Etymologically, overdiagnosis means too much diagnosis and stems from the inability to discern what is important from what is not. Accordingly, in order to grasp, measure, and handle overdiagnosis we should revive medicine's original goal and re-connect diagnosis to what matters (...) to professionals and patients, i.e., knowledge and suffering respectively. This will make overdiagnosis easier to define and measure, and eventually less difficult to reduce.© The Author(s) 2019. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

2019 American Journal of Epidemiology

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