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Orolabial Herpes

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1. Orolabial Herpes

Orolabial Herpes Orolabial Herpes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Orolabial Herpes Orolabial Herpes Aka: Orolabial (...) on the term "Orolabial Herpes." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Herpes Labialis (C0019345) Definition (MEDLINEPLUS) Cold sores are caused by a contagious virus called . There are two types of herpes simplex virus. Type 1 usually causes oral herpes, or cold sores. Type 1 herpes virus infects more than half of the U.S. population by the time they reach their 20s. Type 2 usually affects the Some people have

2018 FP Notebook

2. Viral genetics modulate orolabial HSV-1 shedding in humans. (PubMed)

Viral genetics modulate orolabial HSV-1 shedding in humans. Orolabial herpes simplex virus type 1 (HSV-1) infection has a wide spectrum of severity in immunocompetent persons. To study the role of viral genotype and host immunity, we characterized oral HSV-1 shedding rates and host cellular response, and genotyped viral strains, in monozygotic (MZ) and dizygotic (DZ) twins.A total of 29 MZ and 22 DZ HSV-1-seropositive twin pairs were evaluated for oral HSV-1 shedding for 60 days. HSV-1 strains

2018 Journal of Infectious Diseases

3. Orolabial Herpes

Orolabial Herpes Orolabial Herpes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Orolabial Herpes Orolabial Herpes Aka: Orolabial (...) on the term "Orolabial Herpes." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Herpes Labialis (C0019345) Definition (MEDLINEPLUS) Cold sores are caused by a contagious virus called . There are two types of herpes simplex virus. Type 1 usually causes oral herpes, or cold sores. Type 1 herpes virus infects more than half of the U.S. population by the time they reach their 20s. Type 2 usually affects the Some people have

2015 FP Notebook

4. Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology. (PubMed)

Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology. Herpes simplex virus (HSV) infection is a highly prevalent condition responsible for significant morbidity and occasional mortality each year. Approximately half of all patients infected by HSV will experience at least one recurrence in their lifetime. For these recurrences, traditional therapy has included both suppressive and episodic treatment with nucleoside analogs. In regards (...) to episodic treatment, 2- to 5-day oral regimens are best studied and most commonly reported. As with any medical condition having a well-understood mechanism of action and targeted treatment, therapeutic intervention is only as effective as allowed by patient compliance. Based on these concerns, recent studies have focused on shorter, less complicated, and more affordable options. This review delineates the evidence for single-day treatments of orolabial and genital herpes. Randomized, double-blind

2011 Therapeutics and clinical risk management

5. Herpes Simplex Virus Pneumonia in an Immunocompetent Child on Corticosteroids for Acute Wheezing. (PubMed)

Herpes Simplex Virus Pneumonia in an Immunocompetent Child on Corticosteroids for Acute Wheezing. Herpes simplex virus (HSV) is rarely the cause of pneumonia in immunocompetent patients. We describe a previously healthy child, with no evidence of an immunodeficiency, who presented to the emergency department with severe pneumonia, wheezing, and pleural effusions with a history of orolabial HSV infection. On admission, he was started on antibiotics and systemic corticosteroids but continued

2018 Pediatric Emergency Care

6. Epidemiology of herpes simplex virus type 1 and 2 in Italy: a seroprevalence study from 2000 to 2014 (PubMed)

Epidemiology of herpes simplex virus type 1 and 2 in Italy: a seroprevalence study from 2000 to 2014 Herpes simplex viruses (HSV) are among the most widespread causative agents of human viral infections. HSV-2 is one of the commonest causes of genital disease, while HSV-1 is associated primarily with orolabial ulceration; however, recent changes in HSV epidemiology showed an increase in genital and neonatal herpes particularly caused by HSV-1. The main purpose of this study was to assess

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2017 Journal of preventive medicine and hygiene

7. The Type I Interferon Response and Age-Dependent Susceptibility to Herpes Simplex Virus Infection (PubMed)

The Type I Interferon Response and Age-Dependent Susceptibility to Herpes Simplex Virus Infection Herpes simplex virus type 1 (HSV-1) is a highly prevalent human neurotropic pathogen. HSV-1 infection is associated with a variety of diseases ranging from benign orolabial lesions to more serious and even life-threatening conditions such as herpes simplex keratitis and herpes simplex encephalitis (HSE). HSE is a rare occurrence among healthy adult individuals, but newborns are a particularly

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2017 DNA and cell biology

8. Seroprevalence and Co-Infection of Human Immunodeficiency Virus (HIV) and Herpes Simplex Virus (HSV) Among Pregnant Women in Lokoja, North-Central Nigeria (PubMed)

Seroprevalence and Co-Infection of Human Immunodeficiency Virus (HIV) and Herpes Simplex Virus (HSV) Among Pregnant Women in Lokoja, North-Central Nigeria Herpes simplex virus 1 (HSV-1) is normally associated with orofacial (orolabial) infections and encephalitis, whereas HSV-2 usually causes genital infections and can be transmitted from infected mothers to neonates. The evidence suggesting that HSV is facilitating the spread of the global human immunodeficiency virus (HIV) epidemic

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2016 Iranian Red Crescent medical journal

9. Concomitant herpes simplex virus colitis and hepatitis in a man with ulcerative colitis: Case report and review of the literature. (PubMed)

and outcomes. We also discuss the epidemiology, clinical manifestations, diagnosis, and management of herpes simplex virus infections, focusing specifically on patients with inflammatory bowel disease.A 43-year-old man with ulcerative colitis, previously controlled with an oral 5-aminosalicylic agent, developed symptoms of a colitis flare that did not respond to treatment with systemic corticosteroid therapy. One week later he developed orolabial ulcers and progressive hepatic dysfunction, with markedly (...) elevated transaminases and coagulopathy. He underwent emergent total colectomy when imaging suggested bowel micro-perforation. Pathology from both the colon and liver was consistent with herpes simplex virus infection, and a viral culture of his orolabial lesions and a serum polymerase chain reaction assay also identified herpes simplex virus. He was treated with systemic antiviral therapy and made a complete recovery.Disseminated herpes simplex virus infection with concomitant involvement of the colon

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2016 Medicine

10. Failure of neutral-red photodynamic inactivation in recurrent herpes simplex virus infections. (PubMed)

no significant effect on the rate of resolution of herpetic lesions (P greater than 0.10) or on the frequency of subsequent recurrences (P greater than 0.10), except for orolabial lesions, in which an adverse effect on the rate of subsequent recurrences was observed (P less than 0.05). In the absence of demonstrated efficacy, the routine use of neutral red and light in patients with recurrent herpes simplex virus infections should be discontinued. Furthermore, other photoactive dyes should not be used until (...) Failure of neutral-red photodynamic inactivation in recurrent herpes simplex virus infections. Because photodynamic inactivation of herpes simplex virus infections may not be free of hazard, the efficacy of photodynamic inactivation with neutral red and light was evaluated in a placebo-controlled study of 170 episodes of recurrent herpes simplex virus infection in 96 patients. The preparation of neutral red that was used was shown to photoinactivate herpes simplex virus in vitro, but had

1975 NEJM

11. Herpes Simplex (Overview)

persons who are at an equal risk of acquiring HSV-1 and HSV-2 both orally and genitally, HSV-1 reactivates more frequently in the oral rather than the genital region. On the other hand, HSV-2 reactivates 8-10 times more commonly in the genital region than in the orolabial regions. Reactivation is more common and severe in immunocompromised individuals. [ ] Cellular immunity is an important defense against herpes simplex. Dissemination of herpes simplex infection can occur in people with impaired T (...) Herpes Simplex (Overview) Herpes Simplex: Background, Microbiology, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTgwLW92ZXJ2aWV3 processing > Herpes Simplex Updated: Mar 01, 2018 Author

2014 eMedicine.com

12. Herpes Simplex Virus Infection (Diagnosis)

the slideshow for more information on clinical, histologic, and radiographic imaging findings in HSV-1 and HSV-2. Signs and symptoms HSV causes myriad clinical presentations, as follows: Orolabial infection Genital infection Intrauterine and perinatal infection (herpes neonatorum) Central nervous system infection Infection in immunocompromised hosts Other infections: Herpetic whitlow, herpes gladiatorum, keratoconjunctivitis, Mollaret meningitis, erythema multiforme Clinical features of orolabial HSV (...) Herpes Simplex Virus Infection (Diagnosis) Pediatric Herpes Simplex Virus Infection: Practice Essentials, Background, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY0ODY2LW92ZXJ2aWV3 processing

2014 eMedicine Pediatrics

13. Herpes Simplex Virus Infection (Overview)

the slideshow for more information on clinical, histologic, and radiographic imaging findings in HSV-1 and HSV-2. Signs and symptoms HSV causes myriad clinical presentations, as follows: Orolabial infection Genital infection Intrauterine and perinatal infection (herpes neonatorum) Central nervous system infection Infection in immunocompromised hosts Other infections: Herpetic whitlow, herpes gladiatorum, keratoconjunctivitis, Mollaret meningitis, erythema multiforme Clinical features of orolabial HSV (...) Herpes Simplex Virus Infection (Overview) Pediatric Herpes Simplex Virus Infection: Practice Essentials, Background, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvOTY0ODY2LW92ZXJ2aWV3 processing

2014 eMedicine Pediatrics

14. Herpes Simplex (Diagnosis)

persons who are at an equal risk of acquiring HSV-1 and HSV-2 both orally and genitally, HSV-1 reactivates more frequently in the oral rather than the genital region. On the other hand, HSV-2 reactivates 8-10 times more commonly in the genital region than in the orolabial regions. Reactivation is more common and severe in immunocompromised individuals. [ ] Cellular immunity is an important defense against herpes simplex. Dissemination of herpes simplex infection can occur in people with impaired T (...) Herpes Simplex (Diagnosis) Herpes Simplex: Background, Microbiology, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjE4NTgwLW92ZXJ2aWV3 processing > Herpes Simplex Updated: Mar 01, 2018 Author

2014 eMedicine.com

15. Erythema multiforme

distribution of lesions over the dorsal surfaces of the extensor extremities with minimal mucous membrane involvement. Generally related to infectious diseases and not drug exposure. The most commonly associated infections are herpes simplex virus and Mycoplasma pneumoniae . Other associated infections include hepatitis B, Epstein-Barr virus, cytomegalovirus, histoplasmosis (with concomitant erythema nodosum), orf (parapox virus that can be transmitted from sheep or goats to humans), coccidioidomycosis (...) , Kawasaki disease, herpes zoster, and gardnerella. Associated drugs include aminopenicillins, docetaxel, tumour necrosis factor (TNF)-alpha inhibitors, antimalarials, anticonvulsants, and lidocaine injections. Statin medications have been associated with photo-induced lesions. Vaccines such as hepatitis B, smallpox, varicella, meningococcal, human papillomavirus, and hantavirus, and allergic response to contact allergens have also been known to elicit the disorder. Supportive care and treatment

2018 BMJ Best Practice

16. Erythema multiforme

distribution of lesions over the dorsal surfaces of the extensor extremities with minimal mucous membrane involvement. Generally related to infectious diseases and not drug exposure. The most commonly associated infections are herpes simplex virus and Mycoplasma pneumoniae . Other associated infections include hepatitis B, Epstein-Barr virus, cytomegalovirus, histoplasmosis (with concomitant erythema nodosum), orf (parapox virus that can be transmitted from sheep or goats to humans), coccidioidomycosis (...) , Kawasaki disease, herpes zoster, and gardnerella. Associated drugs include aminopenicillins, docetaxel, tumour necrosis factor (TNF)-alpha inhibitors, antimalarials, anticonvulsants, and lidocaine injections. Statin medications have been associated with photo-induced lesions. Vaccines such as hepatitis B, smallpox, varicella, meningococcal, human papillomavirus, and hantavirus, and allergic response to contact allergens have also been known to elicit the disorder. Supportive care and treatment

2018 BMJ Best Practice

17. Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus

that is currently being treated with suppressive anti-infective therapy, including but not limited to tuberculosis, pneumocystis, CMV, herpes zoster, and atypical mycobacteria, with the exception of historical orolabial or localized cutaneous herpes simplex infections treated with suppressive anti- viral therapy; Receipt of a live-attenuated vaccine within 12 months prior to screening; Concomitant malignancies or a history of malignancy, with the exception of completely treated basal cell carcinoma of the skin

2017 Clinical Trials

18. Acyclovir

Related Chapters II. Indications Primary or Recurrent Infection ( ) HSV Herpes Neonatorum ( ) III. Pharmacokinetics Base Weight calculations on Metabolized by Decrease interval in renal to q12-24h : 50-100% dialyzable IV. Safety: Pregnancy and Lactation FDA Pregnancy Class C Safety unclear in V. Preparations Tablets: 200, 400, 800 mg Suspension: 200 mg/5 ml Buccal tablet (Sitavig) VI. Dosing: Orolabial Herpes (Cold Sores) Adult: 200 mg orally every 4 hours while awake (5x/day) Ped: 15 mg/kg/day (750 (...) : Herpes Neonatorum or Herpes Neonatorum Child: 30 mg/kg/day (1500 mg/m2/day) divided every 8 hours IV VIII. Dosing: Genital Herpes Initial Genital HSV Adult: 200 mg orally 5 times per day for 10 days Episodic Genital HSV Adult: 200 mg orally 5 times per day for 5 days Apply topical Acyclovir to affected area 6 times per day for 7 days Prophylaxis of Genital HSV Adult: 400 mg orally twice daily for up to 12 months IX. Dosing: Varicella Zoster ( ) or Adult Oral: 800 mg orally 5 times/day for 7-10 days

2018 FP Notebook

19. Dermatologic Diseases of the Male Genitalia: Nonmalignant (Diagnosis)

on the following: one or more painful genital ulcers, clinical presentation and lymphadenopathy suggestive of chancroid, and negative laboratory results for T pallidum and herpes simplex virus (HSV). Differential diagnoses The differential diagnoses include syphilis (see ), granuloma inguinale (see ), herpesvirus infection, and LGV (see ). These conditions can often be distinguished based on clinical presentation, serology, evaluation of exudate or ulcer smears, and appropriate microbiological culture

2014 eMedicine.com

20. Oral Manifestations of Systemic Diseases (Treatment)

of the mouth, as well as spontaneous gingival bleeding. [ ] Chemotherapeutic drugs may cause diffuse oral ulceration, also known as mucositis, which is often mistaken to herpes simplex virus (HSV) or cytomegalovirus (CMV) infection. [ ] It is important to distinguish between ulcer etiologies so appropriate treatment can be initiated. Chemotherapeutics used to treat leukemias are often immunosuppressive agents and, thus, increase the risk for secondary viral, fungal, and bacterial infections in the oral

2014 eMedicine.com

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