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Oral Fibroma

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1. Oral Bilateral Collagenous Fibroma: A previously unreported case and literature review Full Text available with Trip Pro

Oral Bilateral Collagenous Fibroma: A previously unreported case and literature review Collagenous fibroma, also known as desmoplastic fibroblastoma, is a rare benign slow growing tumor particularly uncommon in the oral cavity. The aim of this study was to analyze the clinical and histopathological features of an oral collagenous fibroma as well as to compare this data with those reported in an English-literature review. The thirteenth case of collagenous fibroma in the oral cavity (...) cells. Blood vessels were few, as well as inflammatory cells. Immunohistochemical staining was positive for vimentin, α-smooth muscle actin and factor XIIIa and negative for S-100, CD68, CD34, HHF35, desmin and AE1/AE3. The patient remains disease-free 24 months after excision. In conclusion, oral collagenous fibroma should be included in the differential diagnosis of bilateral sessile nodules in the oral cavity. Key words:Connective tissue, mouth diseases, mouth neoplasms, oral diagnosis, oral

2018 Journal of clinical and experimental dentistry

2. Ossifying fibroma in the mandibular angle mimicking metastatic clear cell renal cell carcinoma: A case report. Full Text available with Trip Pro

Ossifying fibroma in the mandibular angle mimicking metastatic clear cell renal cell carcinoma: A case report. Ossifying fibroma is benign fibro-osseous neoplasm. The authors report a case of ossifying fibroma in the mandibular angle suspected as metastasis of clear cell renal cell carcinoma.A 74-year-old man presented to the primary hospital complaining of frequent urination. A tumor in the left kidney was detected via an abdominal computed tomography scan. The patient then visited (...) the Department of Urology at our hospital.According to whole-body imaging examinations, the patient was suspected of having renal cancer with mandibular metastasis. Also, a cystic lesion of the maxilla was revealed.Left nephrectomy was performed by urologists, and the patient was diagnosed with clear cell renal cell carcinoma of the left kidney. Approximately 1 month later, resection with a safety margin of the mandibular lesion and removal of the maxillary lesion were performed by oral and maxillofacial

2019 Medicine

3. Oral Fibroma

Oral Fibroma Oral Fibroma Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Oral Fibroma Oral Fibroma Aka: Oral Fibroma From Related (...) a Bing search on the term "Oral Fibroma." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Oral fibroma (C0948118) Concepts Neoplastic Process ( T191 ) Italian Fibroma della bocca Japanese 口腔線維腫 , コウクウセンイシュ , コウコウセンイシュ Czech Fibrom dutiny ústní English oral fibroma , fibroma oral , Oral fibroma Hungarian Oralis fibroma Portuguese Fibroma oral Spanish Fibroma oral Dutch oraalfibroom French Fibrome de la cavité

2018 FP Notebook

4. Granular cell tumors of the tongue: fibroma or schwannoma Full Text available with Trip Pro

Granular cell tumors of the tongue: fibroma or schwannoma Granular cell tumors are benign lesions that typically occur in the oral cavity, but can also be found in other sites. However, the characteristics of these tumors are unclear. Thus, the present study aimed to investigate the immunohistological characteristics of these tumors of the tongue.Seven patients were treated for granular cell tumors of the tongue at our institution during 2003-2017. Paraffin-embedded specimens were available (...) for all cases; thus, retrospective immunohistochemical analyses were performed.All cases exhibited cytoplasmic acidophilic granules in the muscle layer of the tumor. Both the normal nerve cells and tumor cells also stained positive for PGP9.5, NSE, calretinin, and GFAP. A nucleus of tumor cells was typically present in the margin. The PAS-positive granules were also positive for CD68 (a lysozyme glycoprotein marker). Various sizes of nerve fibers were observed in each tumor, and granular cells were

2018 Head & face medicine

5. Fibroma-like PEComa: A Tuberous Sclerosis Complex-related Lesion. (Abstract)

to stellate spindle-shape cells, prominent collagenous background, and lacked mitotic activity and cytologic atypia. Immunohistochemically, all 3 tumors were positive for HMB-45; smooth muscle actin or desmin was positive in both tumors tested. TFE3 was negative. All patients were alive with no evidence of disease with median follow-up of 55 months (range, 6 to 131 mo). Non-TSC fibroma-like lesions and oral and periungual fibromas were negative for HMB-45. Fibroma-like PEComa, a newly recognized soft (...) Fibroma-like PEComa: A Tuberous Sclerosis Complex-related Lesion. Perivascular epithelioid cell tumor (PEComa), mesenchymal tumors morphologically characterized by epithelioid cells, coexpress melanocytic and muscle markers. Herein, we describe a heretofore-undescribed tuberous sclerosis complex (TSC)-related neoplasm, morphologically resembling a soft tissue fibroma-like lesion, but showing an immunophenotype resembling PEComa. We identified 3 soft tissue fibroma-like lesions in individuals

2018 American Journal of Surgical Pathology

6. Surgical correction of residual facial deformity following conservative excision of a giant maxillary ossifying fibroma: A case report. Full Text available with Trip Pro

Surgical correction of residual facial deformity following conservative excision of a giant maxillary ossifying fibroma: A case report. Ossifying fibroma (OF) is a benign fibro-osseous lesion that can develop in the oral and maxillofacial region. OF is more common in females and has a marked predilection for the mandible, occurring rarely in the maxilla. Lesions grow slowly and are usually asymptomatic until growth produces an obvious swelling, pain, paresthesia, and facial deformity. With low

2018 Medicine

7. Clinicopathological investigation of odontogenic fibroma in tuberous sclerosis complex. (Abstract)

mutation causes abnormal activation of mammalian target of rapamycin (mTOR) downstream of the PI3K-AKT pathway. The odontogenic fibroma in this patient was positive for mTOR, suggesting that the development of the odontogenic fibroma was the result of abnormal activation of mTOR, as in angiofibroma. The clinical course of this patient is presented and the developmental mechanism of central odontogenic fibroma is discussed.Copyright © 2018 International Association of Oral and Maxillofacial Surgeons (...) Clinicopathological investigation of odontogenic fibroma in tuberous sclerosis complex. Tuberous sclerosis complex (TSC) is an autosomal dominant inherited disease characterized by systemic hamartoma and diverse systemic features. TSC1 and TSC2 are the causative genes, and mental retardation, epileptic seizures, and facial angiofibroma develop in many patients with the disease. The case of a patient with TSC who developed a central odontogenic fibroma of the mandible is reported here

2018 International Journal of Oral and Maxillofacial Surgery

8. Pediatric Palatal Fibroma Full Text available with Trip Pro

Pediatric Palatal Fibroma Fibroma is one of the most common soft tissue benign tumors of the oral cavity. These masses represent hyperplasias instead of true neoplasm, which develop due to irritation to the mucosal tissue resulting in proliferation of the cells. Although so common in the oral cavity, its occurrence on the palate is rare, mainly due to fewer chances of trauma. Here, we report a case of palatal fibroma in a child diagnosed on the basis of clinical, radiological, and histological (...) features. The case represents an extremely rare occurrence as unusual trauma due to thumb sucking seemed to be the only apparent traumatic factor in the palatal region.Mishra R, Khan TS, Ajaz T, Agarwal M. Pediatric Palatal Fibroma. Int J Clin Pediatr Dent 2017; 10(1):96-98.

2017 International journal of clinical pediatric dentistry

9. Peripheral Odontogenic Fibroma: A Rare Tumor mimicking a Gingival Reactive Lesion Full Text available with Trip Pro

Peripheral Odontogenic Fibroma: A Rare Tumor mimicking a Gingival Reactive Lesion Gingival growths are one of the most frequently encountered lesions in the oral cavity. A plethora of lesions can be seen having similar clinical presentation, making diagnosis a dilemma. Peripheral odontogenic tumors are rare neoplasms to occur on gingiva, the most common among them being the peripheral odontogenic fibroma (POdF). The POdF is a benign, slow-growing, exophytic lesion. Although considered to have (...) a recurrence potential after excision, the actual recurrence rate is not known due to paucity of reported cases. Presented here is a case of a rare neoplasm mimicking an inflammatory gingival lesion with review of the available literature.Khot K, Deshmane S, Bagri-Manjrekar K, Khot P. Peripheral Odontogenic Fibroma: A Rare Tumor mimicking a Gingival Reactive Lesion. Int J Clin Pediatr Dent 2017;10(1):103-106.

2017 International journal of clinical pediatric dentistry

10. 940 nm Diode Laser assisted excision of Peripheral Ossifying Fibroma in a neonate Full Text available with Trip Pro

940 nm Diode Laser assisted excision of Peripheral Ossifying Fibroma in a neonate Peripheral ossifying fibroma associated with neonatal tooth extraction is a rare, benign reactive lesion, but its nature and location often scares the patient & parents for possibility of neoplasm. A high recurrence rate makes its histopathological examination and long term follow up important.A 2 months old boy presented with enlarging soft tissue growth on the anterior mandibular ridge. The history revealed (...) extraction of two neonatal teeth at 2 weeks of age. Lesion was excised using 940 nm diode laser and histopathological examination revealed hypercellularity and prominent dystrophic calcification, confirming it to be Peripheral Ossifying Fibroma. There was no recurrence after 18 months follow up.Paediatric dentists should be aware of possible outcomes of natal and neonatal teeth extraction and histopathological features of soft tissue lesions in neonates and infants. This report also highlights that 940

2017 Laser therapy

11. Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial (Abstract)

Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial To investigate the noninferiority of relugolix compared with leuprorelin acetate in reducing heavy menstrual bleeding associated with uterine leiomyomas.In a double-blind, double-dummy trial, premenopausal women with uterine leiomyomas and heavy menstrual bleeding defined as a pictorial blood loss assessment chart score of at least 120 were (...) 32.5%; 95% CI: 20.95-44.13%] for weeks 2-6 and pictorial blood loss assessment chart score of 0, 52.6% vs 21.8% [30.7%; 95% CI: 19.45-42.00%] for weeks 2-6) and faster recovery of menses after treatment discontinuation (relugolix median [Q1, Q3], 37 days [32.0, 46.0]; leuprorelin median, 65 days [54.0, 77.0]). Adverse events and bone mineral density loss were similar between relugolix and leuprorelin treatment groups.In women with uterine leiomyomas, once-daily treatment with relugolix, an oral

2019 EvidenceUpdates

12. Desmoplastic fibroblastoma (collagenous fibroma) of the oral cavity Full Text available with Trip Pro

Desmoplastic fibroblastoma (collagenous fibroma) of the oral cavity Desmoplastic fibroblastoma is benign soft tissue tumor, with fibroblastic or myofibroblastic origin, that rarely occurs in oral cavity. We reported the case of a 56-year-old man who presented a tumor in the left mandibular alveolar ridge, with slow and asymptomatic growth, with no osseous involvement. The tumor was sessile with lobulated surface, covered by healthy mucosa with erythematous areas. The lesion was excised (...) and specimens sent to histopathology and immunohistochemistry. Histopathological exam showed a non-encapsulated fibroblastic proliferation, characterized by myofibroblasts, spindle and stellate fibroblasts with large or oval nuclei and bi or tri nucleation, immersed in an abundant hypocellular dense collagen stroma. Tumor cells were positive for vimentin, HHF35, α-smooth muscle actin and factor XIIIa. The diagnosis of desmoplastic fibroblastoma was based in the clinical history of absence of trauma related

2016 Journal of clinical and experimental dentistry

13. A clinical challenging situation of Intra oral fibroma mimicking pyogenic granuloma Full Text available with Trip Pro

A clinical challenging situation of Intra oral fibroma mimicking pyogenic granuloma 26958126 2016 10 31 2016 12 30 1937-8688 22 2015 The Pan African medical journal Pan Afr Med J A clinical challenging situation of intra oral fibroma mimicking pyogenic granuloma. 263 10.11604/pamj.2015.22.263.8080 Krishnan Velavan V Consultant Oral and Maxillofacial Surgeon, Saraswathy Multispeciality Hospital, Balaiah Garden, Madipakkam, Chennai, Tamil Nadu 600091, India. Shunmugavelu Karthik K Consultant (...) Dental Surgeon, Saraswathy Multispeciality Hospital, Balaiah Garden, Madipakkam, Chennai, Tamil Nadu 600091, India. eng Case Reports Journal Article 2015 11 19 Uganda Pan Afr Med J 101517926 IM Diagnosis, Differential Female Fibroma diagnosis pathology Granuloma, Pyogenic diagnosis pathology Humans Middle Aged Mouth Diseases diagnosis pathology Mouth Neoplasms diagnosis pathology Fibroma mimicking Pyogenic Granuloma maxillary occlusal orthopantomograph 2015 10 01 2015 11 04 2016 3 10 6 0 2015 1 1 0 0

2015 The Pan African medical journal

14. Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids

(69g) TSD decoction boiled as 200ml per bag; 2 bags per day, 6 days per week; Orally in-take one bag of TSD decoction in morning and another in evening after meal; The whole treatment lasts for 16 weeks. Other Name: Tumor-shrinking Decoction, Chinese medicine preparation Outcome Measures Go to Primary Outcome Measures : Changes in the score of Uterine Fibroid Symptom and Quality of Life questionnaire (UFS-QOL) from Baseline to 6 months [ Time Frame: Baseline and once per month thereafter; Up to 6 (...) Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2014 Clinical Trials

15. Utian Translational Science Symposium report: New Ttherapies for Leiomyomas: When Surgery May Not Be the Best Option

OncetheybecomeavailableintheUnitedStates,UPAand, possibly, VPR can be treatment options for women with symptomatic uterine leiomyomas who desire conservative management of their uterine bleeding and preservation for future fertility. HELPING WOMEN WITH FIBROIDS NAVIGATE THE MENOPAUSE TRANSITION AND POSTMENOPAUSE HORMONE THERAPY Nanette F. Santoro, MD Uterine leiomyomas are the most common tumors of the female genital tract, occurring in 20% to 80% of women. Uterineleiomyomasareoftenclinicallysilent,butdepending on their size (...) that have shown promise in targeting them in clinical trials. MANAGEMENT OF WOMEN WITH UTERINE LEIOMYOMAS: WHY WE NEED NEW OPTIONS Wendy L. Wolfman, MD, FRCS(C), FACOG, NCMP Uterine leiomyomas are monoclonal smooth-muscle tumors originating from the myometrium, affecting up to 70% of white women and 80% of black women by the age of menopause. 1,2 Fifty percent of women with leiomyomas experience significant health effects because of the triad of bleeding, bulk, or reproductive complications. 3,4 Loss

2018 The North American Menopause Society

16. Desmoplastic fibroma of the mandible in young children-a case series. (Abstract)

, there has been no recurrence and all rib grafts were successfully incorporated. The case treated by chemotherapy has persistence of the tumour, but it is not progressing. Desmoplastic fibromas in young children respond well to wide mandibular resection and immediate reconstruction with rib grafts. Chemotherapy may halt progression.Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. (...) Desmoplastic fibroma of the mandible in young children-a case series. Desmoplastic fibromas are rare, benign, but aggressive lesions, affecting predominantly young people, with an affinity for the mandible. Four patients with desmoplastic fibromas of the mandible, seen between 1995 and 2015 with long-term follow-up, were identified. Three were treated by wide mandibular resection and immediate reconstruction with rib grafts, and one was treated with chemotherapy. In the three resected cases

2016 International Journal of Oral and Maxillofacial Surgery

17. Giant Cell Fibroma in a Two-Year-Old Child Full Text available with Trip Pro

Giant Cell Fibroma in a Two-Year-Old Child The giant cell fibroma is a benign nonneoplastic fibrous tumor of the oral mucosa. It occurs in the first three decades of life in the mandibular gingiva, predominantly, showing predilection for females. This article reports a case of giant cell fibroma in a 2-year-old girl, which is an uncommon age for this lesion. The patient was brought for treatment at the Research and Clinical Center of Dental Trauma in Primary Teeth, where practice (...) for the Discipline of Pediatric Dentistry (Faculty of Dentistry, University of São Paulo, Brazil) takes place. During clinical examination, a tissue growth was detected on the lingual gingival mucosa of the lower right primary incisors teeth. The lesion was excised under local anesthesia and submitted to histological examination at the Oral Pathology Department of the Faculty of Dentistry, University of São Paulo, which confirmed the diagnosis of giant cell fibroma. There was no recurrence after 20 months

2016 Case reports in dentistry

18. An Unusually Large Irritation Fibroma Associated with Gingiva of Lower Left Posterior Teeth Region Full Text available with Trip Pro

An Unusually Large Irritation Fibroma Associated with Gingiva of Lower Left Posterior Teeth Region Fibroma is a benign tumor of oral cavity, with usually the tongue, gingiva, and buccal mucosa being the most common sites. Females are twice more likely to develop fibroma than males. The intraoral fibroma typically is well demarcated; and its size can vary from millimeter to few centimeters. Intraorally the growth is attached to the mucosa by means of a peduncle. Fibroma is generally slow growing (...) , painless, smooth surface lesion and the color is slightly paler than the adjacent healthy tissue. Treatment usually requires total excision and recurrence is rare. Here we present a case of 37-year-old female patient reported to the Department of Oral Medicine and Radiology with the chief complaint of a growth in the lower left posterior teeth region 3 months earlier.

2016 Case reports in dentistry

19. Giant Cell Fibroma in a Paediatric Patient: A Rare Case Report Full Text available with Trip Pro

Giant Cell Fibroma in a Paediatric Patient: A Rare Case Report Giant cell fibroma is a form of fibrous tumour affecting the oral mucosa. Its occurrence is relatively rare in paediatric patients. Clinically it is presented as a painless, sessile, or pedunculated growth which is usually confused with other fibrous lesions like irritation fibromas. Here we are presenting a case where a seven-year-old male patient reported with a painless nodular growth in relation to lingual surface of 41 and 42 (...) . Considering the size and location of the lesion, excisional biopsy was performed and sent for histopathological analysis which confirmed the lesion as giant cell fibroma.

2015 Case reports in dentistry

20. Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases. (Abstract)

Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases. The management of patients with juvenile ossifying fibroma (JOF) remains controversial. To explore the correlations between different treatments and the patient prognosis, 15 cases of JOF of the jaw were reviewed. Five patients were male and 10 were female. Patient age at the time of disease onset ranged from 7 to 18 years (mean 10.9 years). Nine tumours were located in mandible and six in the maxilla. These cases (...) underwent conservative treatment, among whom six (6/9, 66.7%) had one or more recurrence. At the end of the follow-up period, 12 patients had no evidence of tumour recurrence and three cases were alive with a tumour. In summary, surgeons should develop the surgical plan according to the extent of the lesion, relapse status, growth rate, and family choice, and these patients should be followed up closely.Copyright © 2015 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier

2015 International Journal of Oral and Maxillofacial Surgery

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