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Onychomadesis

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1. Mucous membrane pemphigoid-associated paronychia with onychomadesis. (PubMed)

Mucous membrane pemphigoid-associated paronychia with onychomadesis. Mucous membrane pemphigoid (MMP) is an autoimmune blistering disease that is notoriously difficult to treat. Nail involvement in MMP is rare.We report on a 58 years old man with severe MMP who presented with onychomadesis.To our knowledge, mucous membrane pemphigoid associated paronychia and onychomadesis have not been reported before. We believe it is important for dermatologists to be aware of this entity.

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2019 BMC Dermatology

2. Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease (PubMed)

Chronic Paronychia and Onychomadesis in Pemphigus Vegetans: An Unusual Presentation in a Rare Autoimmune Disease Pemphigus vegetans is a rare variant of deep acantholytic pemphigus which usually presents with vesiculobullous rash and vegetative plaques on the folds. We report a case of pemphigus vegetans patient who presented with rashes on tips of fingers and toes resembling paronychia and onychomadesis that misled the diagnosis for months. The final diagnosis of Hallopeau-type pemphigus

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2018 Case reports in medicine

3. Onychomadesis as a Late Complication of Hand-Foot-Mouth Disease: A Case Series Shedding Light on Nail Shedding. (PubMed)

Onychomadesis as a Late Complication of Hand-Foot-Mouth Disease: A Case Series Shedding Light on Nail Shedding. Hand-foot-mouth disease is a viral illness frequently caused by enterovirus and coxsackievirus. Traditionally, this disease initially causes malaise, fever, and rash with vesicles in the mouth, as well as on the hands and feet. Occasionally, more severe presentations and late postinfectious sequelae occur, including onychomadesis, nail matrix arrest. We describe a series of 4 cases (...) of onychomadesis and its evaluation following recent hand-foot-mouth disease during this current enteroviral season as a way to ensure appropriate clinician diagnosis and guidance.

2017 Pediatric Emergency Care

4. Haemorrhagic onychomadesis: a cutaneous clue to chronic selenosis - case series. (PubMed)

Haemorrhagic onychomadesis: a cutaneous clue to chronic selenosis - case series. 28342188 2017 09 14 1468-3083 31 9 2017 Sep Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Haemorrhagic onychomadesis: a cutaneous clue to chronic selenosis - case series. e425-e427 10.1111/jdv.14241 Razmi T M M Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. Attri S V SV

2017 Journal of the European Academy of Dermatology and Venereology

5. Onychomadesis after hand-foot-and-mouth disease (PubMed)

Onychomadesis after hand-foot-and-mouth disease 28246241 2017 10 16 2018 11 13 1488-2329 189 7 2017 02 21 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Onychomadesis after hand-foot-and-mouth disease. E279 10.1503/cmaj.160388 Gan Xue-Ling XL Department of Dermatology, Zhujiang Hospital, Southern Medical University, Guangzhou, China. Zhang Tang-de TD Department of Dermatology, Zhujiang Hospital, Southern Medical University, Guangzhou, China tdgz

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2017 CMAJ : Canadian Medical Association Journal

6. Onychomadesis: A rare adverse effect in early-period valproic acid therapy (PubMed)

Onychomadesis: A rare adverse effect in early-period valproic acid therapy Valproic acid is an effective, frequently used anticonvulsant drug. Typical adverse effects include weight gain, hair loss, and nausea. Hyperpigmentation, onycholysis, and onychomadesis are nail changes that can be seen after valproic acid use. Changes occur at the distal and proximal portions of the nail bed in onycholysis and onychomadesis, respectively. Onychomadesis is a very rare disease of childhood (...) with the exception of systemic and genetic diseases. Here, we present a child aged 23 months, the youngest and the earliest isolated patient with onychomadesis, which occurred after valproic acid treatment and worried the family but resolved spontaneously. The improvement of this very rare adverse effect of antiepileptic drugs after cessation of valproic acid without treatment is emphasized.

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2017 Turkish Archives of Pediatrics/Türk Pediatri Arşivi

7. Onychomadesis in a 9-month-old boy with hand-foot-mouth disease (PubMed)

Onychomadesis in a 9-month-old boy with hand-foot-mouth disease Nail abnormalities in childhood are generally uncommon. Recently, onychomadesis is described as a rare, late complication of hand-foot-mouth disease, which is a viral illness commonly seen in the pediatric age group. It is therefore important to elucidate the presentation of this entity, especially in the context of the hand-foot-mouth disease.We report a case of onychomadesis in a 9-month old Lebanese boy who presented (...) to the emergency department with rapidly progressing nail changes involving all four extremities. These changes appeared few days after the healing of cutaneous lesions of hand-foot-mouth disease.This case highlights the importance of recognizing the association between onychomadesis and hand-foot-mouth disease in order to avoid unnecessary treatment and to reassure the patient's parents.

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2017 International journal of emergency medicine

8. Onychomadesis associated with chemotherapy: case report and mini literature review (PubMed)

Onychomadesis associated with chemotherapy: case report and mini literature review The side effects of chemotherapy drugs have increased in recent years, and some side effects can lead to onychomadesis. A 72-year-old woman who was diagnosed with an invasive ductal carcinoma of the right breast underwent a modified radical mastectomy in April 2015, followed by chemotherapy with capecitabine and nanoparticle albumin-bound paclitaxel (nab-paclitaxel). Subsequently, the patient experienced (...) palmoplantar redness, pain, onycholysis, a transparent serous exudate, and onychomadesis. The chemotherapy was discontinued, and the patient was treated with oral vitamin B6, a polymyxin ointment, and a high-energy red light. The palmoplantar redness and pain were alleviated after 1 month. However, although her fingernails improved, dysesthesia symptoms remained, and all her toenails exhibited defects or deformities at a 24-month follow-up. The symptoms of this disorder should be recognized

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2017 Drug design, development and therapy

9. Onychomadesis

Onychomadesis Onychomadesis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Onychomadesis Onychomadesis Aka: Onychomadesis From (...) to external sites (from Bing) These images are a random sampling from a Bing search on the term "Onychomadesis." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Onychomadesis (C0263540) Definition (NCI) Loss of all or a portion of a nail. Definition (NCI_CTCAE) A disorder characterized by loss of all or a portion of the nail. Concepts Sign or Symptom ( T184 ) SnomedCT 22743000 English Spont shed nail from matrix

2018 FP Notebook

10. Idiopathic Sporadic Onychomadesis of Toenails (PubMed)

Idiopathic Sporadic Onychomadesis of Toenails Onychomadesis is a clinical sign of nail plate separation due to transient or permanent arrest of nail matrix activities. Onychomadesis can be considered as a severe form of Beau's line. This condition usually occurs after trauma, causal diseases, or medications, yet it rarely occurs as an idiopathic condition. We report a case of a 38-year-old Thai female who developed recurrence onychomadesis in several toenails in the absence of predisposing (...) factors or associated conditions. To the best of our knowledge, our patient is the first reported case of idiopathic onychomadesis limited to toenails.

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2016 Case reports in dermatological medicine

11. Beau lines, onychomadesis, and retronychia: A unifying hypothesis. (PubMed)

Beau lines, onychomadesis, and retronychia: A unifying hypothesis. Beau lines, onychomadesis, and retronychia are nail dystrophies with distinctive clinical findings. Trauma has been reported as the initiating factor in each of these entities. Infections, severe medical illnesses, major surgery/anesthesia, medication side effects, and autoimmune disease can produce Beau lines and onychomadesis. This article illustrates the common underlying pathophysiological mechanism that produces each

2015 Journal of American Academy of Dermatology

12. Onychomadesis after hand-foot-and-mouth disease outbreak in northern Greece: case series and brief review of the literature. (PubMed)

Onychomadesis after hand-foot-and-mouth disease outbreak in northern Greece: case series and brief review of the literature. Nail abnormalities in childhood are generally uncommon. Recently, onychomadesis was described as a late complication of hand-foot-and-mouth disease (HFMD). Onychomadesis outbreaks following HFMD have been reported in many countries worldwide.To present a case series of onychomadesis in children, following HFMD outbreak in Northern Greece, and review literature (...) data.Children with evident onychomadesis attending the outpatient clinic between November 2012 and January 2013 were included in the study. A questionnaire including demographic personal and family history information of the children was completed by the parents. Patients were clinically examined, and their pediatric and dermatological records were studied to confirm precedent HFMD. Direct microscopic examination and cultures for fungi were performed. Exposure of participants to coxsackievirus, based

2015 International Journal of Dermatology

13. A treatment study of canine symmetrical onychomadesis (symmetrical lupoid onychodystrophy) comparing fish oil and cyclosporine supplementation in addition to a diet rich in omega-3 fatty acids. (PubMed)

A treatment study of canine symmetrical onychomadesis (symmetrical lupoid onychodystrophy) comparing fish oil and cyclosporine supplementation in addition to a diet rich in omega-3 fatty acids. Treatment of symmetrical onychomadesis (symmetrical lupoid onychodystrophy) is a challenging task for dermatologists. The acute phase is characterized by sloughing of claw plates and loose claws have to be removed and secondary infections treated. The goal of long-term treatment is to allow claws to re (...) -grow with normal quality and to achieve life-long lack of recurrence. The aim of this randomized treatment trial was to see if adding fish oil or cyclosporine to a diet rich in omega-3 could improve the treatment outcome of symmetrical onychomadesis in Gordon and English setters. All dogs were fed Eukanuba Veterinary Diets Dermatosis® exclusively during the six month treatment trial. The treatment outcome was measured as the change in number of healthy claws during treatment, as well as the long

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2015 Acta veterinaria Scandinavica

14. Onychomadesis: Literature Review. (PubMed)

Onychomadesis: Literature Review. Onychomadesis is characterized by separation of the nail plate from the matrix with persistent attachment to the nail bed and often, but not always, eventual shedding. Onychomadesis has been associated with infection, autoimmune disease, critical illness and medications. To our knowledge a literature review of all associations with onychomadesis has not been completed previously. Most commonly, onychomadesis has been reported in association with pemphigus (...) vulgaris and hand-foot-mouth disease, and following chemotherapy or antiepileptic medications. This article summarizes these key culprit associations, postulates the pathogenesis of nail matrix arrest and summarizes the clinical outcomes. We conducted a retrospective review of cases of onychomadesis reported from January 1960 to March 2013. Using the PubMed database, the literature was searched using the following terms: 'onychomadesis' and 'proximal nail shedding'. Also, an Ovid search was carried out

2014 British Journal of Dermatology

15. Onychomadesis

Onychomadesis Onychomadesis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Onychomadesis Onychomadesis Aka: Onychomadesis From (...) to external sites (from Bing) These images are a random sampling from a Bing search on the term "Onychomadesis." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Onychomadesis (C0263540) Definition (NCI) Loss of all or a portion of a nail. Definition (NCI_CTCAE) A disorder characterized by loss of all or a portion of the nail. Concepts Sign or Symptom ( T184 ) SnomedCT 22743000 English Spont shed nail from matrix

2015 FP Notebook

16. Onychomadesis Developed Only on the Nails Having Cutaneous Lesions of Severe Hand-Foot-Mouth Disease (PubMed)

Onychomadesis Developed Only on the Nails Having Cutaneous Lesions of Severe Hand-Foot-Mouth Disease This paper reported a case of onychomadesis which appeared on the nails after heal of cutaneous lesions of hand-foot-mouth disease (HFMD). There were a few reports describing onychomadesis after HFMD; however, the mechanism is still unclear. The present case was prospectively observed, and onychomadesis was found to develop only on the nails having cutaneous lesions of HFMD. We considered (...) that nail dysfunction due to direct inflammation spreading from skin eruptions around nail is one of the causes of onychomadesis linked to HFMD.

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2011 Case reports in dermatological medicine

17. An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated with onychomadesis in Taiwan, 2010. (PubMed)

An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated with onychomadesis in Taiwan, 2010. In 2010, an outbreak of coxsackievirus A6 (CA6) hand, foot and mouth disease (HFMD) occurred in Taiwan and some patients presented with onychomadesis and desquamation following HFMD. Therefore, we performed an epidemiological and molecular investigation to elucidate the characteristics of this outbreak.Patients who had HFMD with positive enterovirus isolation results were enrolled. We (...) %) CA6 patients developed onychomadesis, which only occurred in 7 (5%) of 145 cases with non-CA6 enterovirus infection (p < 0.001). The sequences of viral protein 1 of CA6 in 2010 differ from those found in Taiwan before 2010, but are similar to those found in patients in Finland in 2008.HFMD patients with CA6 infection experienced symptoms targeting a broader spectrum of skin sites and more profound tissue destruction, i.e., desquamation and nail abnormalities.

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2011 BMC Infectious Diseases

18. Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008. (PubMed)

Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008. Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by onychomadesis (nail shedding), occurred during summer and fall 2008 in Valencia, Spain. Fecal samples from onychomadesis patients, who did or did not have previous HFMD, and from healthy children exposed to onychomadesis patients tested positive (...) for EV. The complete viral protein 1 capsid gene sequence was obtained for typing and phylogenetic analysis. Two EV serotypes, coxsackievirus A10 and coxsackievirus B1 (CVB1), were mainly detected as a monoinfection or co-infection in a childcare center where an onychomadesis outbreak occurred. On the basis of our results, and detection of CVB1 in 2 other contemporary onychomadesis outbreaks in childcare centers in Spain, we propose that mixed infection of an EV serotype that causes HFMD, plus

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2011 Emerging Infectious Diseases

19. Nail Dystrophy (Onychomadesis) (PubMed)

Nail Dystrophy (Onychomadesis) 19991264 2010 06 24 2010 06 24 0035-9157 30 11 1937 Sep Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Nail Dystrophy (Onychomadesis). 1341-2 Sherry-Dottridge F F eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1937 9 1 0 0 1937 9 1 0 1 ppublish 19991264 PMC2076508

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1937 Proceedings of the Royal Society of Medicine

20. Seasonal onychomadesis in an elderly gentleman (PubMed)

Seasonal onychomadesis in an elderly gentleman A 79-year-old man with a history of dementia and hypertension initially presented with a ten year history of Beau's lines and seasonal nail shedding of his fingernails only. He denied any exposure to heavy metals, unusual activities or food. He stated that the seasonal nail shedding had been occurring for the last 5-10 years. On examination, six out of ten fingernails had been affected. He had significant toenail dystrophy. Fungal cultures and PAS

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2010 Dermatology Reports

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