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Observed Affect

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121. Effects of radial extracorporeal shockwave therapy on spasticity of upper-limb agonist/antagonist muscles in patients affected by stroke: a randomized, single-blind clinical trial Full Text available with Trip Pro

Effects of radial extracorporeal shockwave therapy on spasticity of upper-limb agonist/antagonist muscles in patients affected by stroke: a randomized, single-blind clinical trial Effects of Radial Extracorporeal Shockwave Therapy on Spasticity of Upper-Limb Agonist/Antagonist Muscles in Patients Affected by Stroke: A Randomized, Single-Blind Clinical Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome (...) collection Add to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Age Ageing Actions 2019 Dec 17 [Online ahead of print] Effects of Radial Extracorporeal Shockwave Therapy on Spasticity of Upper-Limb Agonist/Antagonist Muscles in Patients Affected

2018 EvidenceUpdates

122. Does Lateral Extra-articular Tenodesis of the Knee Affect Anterior Cruciate Ligament Graft In Situ Forces and Tibiofemoral Contact Pressures? (Abstract)

Does Lateral Extra-articular Tenodesis of the Knee Affect Anterior Cruciate Ligament Graft In Situ Forces and Tibiofemoral Contact Pressures? To quantify the effects of lateral extra-articular tenodesis (LET) on tibiofemoral compartment contact area and pressures, knee kinematics, and forces.Nine cadaveric knees were tested using a robotic testing system. Two loading conditions, (1) anterior tibial translational load coupled with axial compression and (2) internal tibial torque coupled (...) % and 50% from the ALC-deficient to post-LET knee states at 60° (P = .02) and 90° (P = .006). No significant difference in kinematics was observed between the ALC-competent and post-LET knee states in each of the loading conditions at all knee flexion angles (P > .05).In this in vitro model, LET with a semitendinosus graft did not significantly overconstrain the knee or increase pressure in the lateral compartment. Additionally, LET reduced the in situ force in the ACL in the setting of ALC injury.The

2020 Arthroscopy

123. Does orthodontic treatment affect caries levels? (Abstract)

Does orthodontic treatment affect caries levels? Design A prospective cohort study.Exposure/sample selection In 2005/2006, the authors analysed data from participants in a previous oral epidemiological study conducted in 1988/1989. Children whom were clinically examined in the School Dental Clinics in South Australia in 1988/1989 were invited to a follow-up in 2005/2006. Respondents competed a questionnaire concerning their sociodemographic characteristics, dental health behaviours (...) on their statistical significance from multiple linear regression models, with the p value set at 0.05.Results The response rate for the questionnaire was 34% (n = 632), with 74% (n = 473) of those attending for clinical examination. After exclusions, 24% (n = 448) of those originally contacted participated. Statistically significant differences in clinical outcomes were observed between those who had and had not visited the dentist in the last two years. These outcomes included missing teeth (MT), filled teeth

2020 Evidence Based Dentistry

124. Form-Deprivation and Lens-Induced Myopia Are Similarly Affected by Pharmacological Manipulation of the Dopaminergic System in Chicks. Full Text available with Trip Pro

Form-Deprivation and Lens-Induced Myopia Are Similarly Affected by Pharmacological Manipulation of the Dopaminergic System in Chicks. Animal models have demonstrated a link between decreases in retinal dopamine levels and the development of form-deprivation myopia (FDM). However, the consistency of dopamine's role in the other major form of experimental myopia, that of lens-induced myopia (LIM), is less clear, raising the question as to what extent dopamine plays a role in human myopia (...) . To determine the receptor subtype by which dopamine and ADTN inhibit FDM and LIM, both compounds were coadministered with either the dopamine D2-like antagonist spiperone (0.005 µmol) or the D1-like antagonist SCH-23390 (0.005 µmol).Intravitreal administration of dopamine or ADTN inhibited the development of FDM (ED50 = 0.003 µmol and ED50 = 0.011 µmol, respectively) and LIM (ED50 = 0.002 µmol and ED50 = 0.010 µmol, respectively) in a dose-dependent manner, with a similar degree of protection observed

2020 Investigative Ophthalmology & Visual Science

125. Vascular Density of Deep, Intermediate and Superficial Vascular Plexuses Are Differentially Affected by Diabetic Retinopathy Severity. Full Text available with Trip Pro

Vascular Density of Deep, Intermediate and Superficial Vascular Plexuses Are Differentially Affected by Diabetic Retinopathy Severity. The purpose of this study was to evaluate differences in optical coherence tomography angiography (OCTA) metrics in the superficial (SCP), intermediate (ICP), and deep (DCP) vascular plexuses across diabetic retinopathy (DR) severity levels.This was a cross sectional observational retrospective chart review study. Eligible patients with diabetes who underwent (...) of each of the three individual layers decreases with increasing DR severity, DR severity has a substantially different effect on OCTA parameters within each layer. Vascular changes in eyes with no to early DR were present primarily in the deeper vascular layers, whereas in eyes with advanced DR the opposite was observed. This study highlights the effects of ICP and the importance of assessing SCP and DCP changes independently across each DR severity level.

2020 Investigative Ophthalmology & Visual Science

126. Transgenic Cry1Ac cotton does not affect the development and fecundity of Chrysoperla carnea. Full Text available with Trip Pro

Transgenic Cry1Ac cotton does not affect the development and fecundity of Chrysoperla carnea. The development and fecundity of the predator Chrysoperla carnea Stephens (Neuroptera: Chrysopidae) were assessed by feeding Aphis gossypii Glover (Hemiptera: Aphididae) that had been reared on transgenic Bacillus thuringiensis (Bt) cotton SGK321 and a non-Bt cotton control (SY321) for two successive generations. We found no significant differences in the developmental stage duration, stage survival (...) , or egg hatch rate between C. carnea fed A. gossypii reared on the Bt and non-Bt cotton. The fecundity per female over a 25-day observation period was very similar between treatments; for C. carnea fed A. gossypii reared on SGK321 vs. SY321, the amount of eggs laid was not significantly different in both generations. Furthermore, a population dynamics of A. gossypii and lacewing (mainly C. carnea) were highly similar in the SGK321 and SY321 treatments during 2016-2017. These results suggest that Bt

2019 PLoS ONE

127. Participation-performance tension and gender affect recreational sports clubs' engagement with children and young people with diverse backgrounds and abilities. Full Text available with Trip Pro

is understood, experienced and managed in junior sport. The study combined in-depth interviews (n = 101), surveys (n = 450) and observations over a three-year period. The results revealed that a focus on performance and competitiveness negatively affected junior sports clubs' commitment to diversity and inclusive participation. Gender and a range of attitudes about diversity were also strongly related. On average, we found that those who identified as men were more likely to support a pro-performance stance (...) Participation-performance tension and gender affect recreational sports clubs' engagement with children and young people with diverse backgrounds and abilities. Sport participation has been shown to be associated with health and social benefits. However, there are persisting inequities and barriers to sport participation that can prevent children and young people with diverse backgrounds and abilities from accessing these benefits. This mixed methods study investigated how diversity

2019 PLoS ONE

128. Maternal protein restriction during perinatal life affects lung mechanics and the surfactant system during early postnatal life in female rats. Full Text available with Trip Pro

Maternal protein restriction during perinatal life affects lung mechanics and the surfactant system during early postnatal life in female rats. Limited information is available on how fetal growth retardation (FGR) affects the lung in the neonatal period in males and females. This led us to test the hypothesis that FGR alters lung mechanics and the surfactant system during the neonatal period. To test this hypothesis a model of FGR was utilized in which pregnant rat dams were fed a low protein (...) and higher tissue elastance which was observed in FGR female offspring at day 21 compared to control offspring. In addition, female LP offspring exhibited lower surfactant pool sizes at postnatal day 1compared to controls. These changes were not observed in the male offspring. It is concluded that FGR has a different impact on pulmonary function and on surfactant in female, as compared to male, offspring.

2019 PLoS ONE

129. The role of low-level image features in the affective categorization of rapidly presented scenes. Full Text available with Trip Pro

are also exploited by the human visual system. Subsequently, we tested observers' rapid classification of affective and neutral naturalistic scenes, presented briefly (~33.3 ms) and backward masked with synthetic textures. We tested categorization accuracy across three distinct experimental conditions, using: (i) original images, (ii) images having their amplitude spectra swapped within a single affective image category (e.g., an aversive image whose amplitude spectrum has been swapped with another (...) The role of low-level image features in the affective categorization of rapidly presented scenes. It remains unclear how the visual system is able to extract affective content from complex scenes even with extremely brief (< 100 millisecond) exposures. One possibility, suggested by findings in machine vision, is that low-level features such as unlocalized, two-dimensional (2-D) Fourier spectra can be diagnostic of scene content. To determine whether Fourier image amplitude carries any

2019 PLoS ONE

130. Feather colour affects the aggressive behaviour of chickens with the same genotype on the dominant white (I) locus. Full Text available with Trip Pro

Feather colour affects the aggressive behaviour of chickens with the same genotype on the dominant white (I) locus. Aggression in chickens is a serious economic and animal welfare issue in poultry farming. Pigmentation traits have been documented to be associated with animal behaviour. Chicken pecking behaviour has been found to be related to feather colour, with premelanosome protein 17 (PMEL17) being one of the candidate genes. In the present study, we performed a genotypic and phenotypic (...) to determine whether the feather colour alone affected the behaviour, given that the genetic background should be the same except for feather colour. The aggressiveness was recorded 5 days after sexual maturity at 26 weeks. Generally, white plumage hens showed significantly higher aggressiveness compared to the red ones in chasing, attacking, pecking, and threatening behaviour traits. We assessed three candidate feather colour genes-PMEL17, solute carrier family 45 member 2 (SLC45A2), and SRY-box 10 (SOX10

2019 PLoS ONE

131. Decidual NK cell-derived conditioned medium from miscarriages affects endometrial stromal cell decidualisation: endocannabinoid anandamide and tumour necrosis factor-α crosstalk. (Abstract)

Decidual NK cell-derived conditioned medium from miscarriages affects endometrial stromal cell decidualisation: endocannabinoid anandamide and tumour necrosis factor-α crosstalk. What are the effects of endocannabinoid anandamide (AEA) in uterine natural killer (unK) cells from miscarriage decidua, regarding their cytokine profile and endometrial stromal cell (ESC) crosstalk?uNK-conditioned media from miscarriage samples present high TNF-α levels which inhibit ESC decidualisation.AEA plasma (...) microenvironments, such as the feto-maternal interface, the mechanisms may not be exactly the same. Also, the inflammatory events of miscarriage that, in this study, have happened prior to processing of the samples may cause different responses to that observed. In addition, the magnitude of the inflammatory response, required to trigger the AEA pathways that impact decidualisation and the uNK angiogenic ability in vivo, is still unclear.The endocannabinoid AEA is a modulator of reproductive competence. AEA

2020 Human Reproduction

132. Do physical activity, sitting time and body mass index affect fertility over a 15-year period in women? Data from a large population-based cohort study. (Abstract)

Do physical activity, sitting time and body mass index affect fertility over a 15-year period in women? Data from a large population-based cohort study. Do physical activity (PA), sitting time (ST) and body mass index (BMI) affect fertility over a 15-year period in Australian women?Moderate and high levels of PA confer advantages for fertility in women with normal BMI, but increased risk of infertility was observed in obese women.Higher BMI is positively associated with higher rates of problems (...) of young adult Australian women, and the results indicate that these are inversely associated with physical activity levels and positively associated with BMI. However, the high infertility risk in obese women was not attenuated by high levels of PA. The protective effects of PA were only observed in women with normal BMI. As rates of developing problems with fertility were highest in every survey interval among women who reported low levels of physical activity and in women who were obese

2020 Human Reproduction

133. Effects of pharmacological treatments on neuroimaging findings in first episode affective psychosis: A review of longitudinal studies. (Abstract)

Effects of pharmacological treatments on neuroimaging findings in first episode affective psychosis: A review of longitudinal studies. Affective psychosis is a common mental disorder characterized by structural/functional brain abnormalities, which seem to occur also at the early stages of the disease. However, the role of psychotropic medications on brain structure and function in affective first episode psychosis (A-FEP) still remains uncertain. Therefore, with this review we aim to gain more (...) robust understanding regarding the potential effect of pharmacological treatments on the brain in A-FEP patients also experiencing a first manic episode.A search on PuBMed and Web of Science of longitudinal structural and functional Magnetic Resonance Imaging (MRI) as well as Diffusion Tensor Imaging (DTI) studies, exploring the effect of medications on the brain in A-FEP, was conducted. We selected nine studies, three randomized or pseudo-randomized controlled trials and six observational

2020 Journal of Affective Disorders

134. Hand Grip Strength May Affect the Association Between Anticholinergic Burden and Mortality Among Older Patients Discharged from Hospital. (Abstract)

Hand Grip Strength May Affect the Association Between Anticholinergic Burden and Mortality Among Older Patients Discharged from Hospital. The relationship between anticholinergic burden and mortality is unclear, and the impact of anticholinergic burden on prognosis may vary in the presence of other conditions common in old age. We aimed to investigate the role of hand grip strength as a potential effect modifier in the association between anticholinergic burden and 1-year mortality in older (...) patients discharged from hospital.Our series consisted of 620 older patients consecutively admitted to seven geriatric and internal medicine acute care wards in the context of a prospective multicenter observational study. Overall anticholinergic burden was assessed by Anticholinergic Cognitive Burden (ACB) score. Hand grip strength was assessed by the use of a North Coast medical hand dynamometer and categorized by using sex-specific cut-offs (women < 15 kg, men < 20 kg). The study outcome was 1-year

2020 Drugs & Aging

135. Do Nontechnical Skills Affect Legal Outcomes After Endoscopic Perforations? (Abstract)

Do Nontechnical Skills Affect Legal Outcomes After Endoscopic Perforations? Health systems often emphasize technical skills to reduce iatrogenic injuries. Nontechnical skills such as clinical and communication skills are mostly overlooked or not readily retrievable from medical records. Our aim was to estimate the association of technical and nontechnical skills of endoscopists with indemnity payments to patients after endoscopic perforations.This is an observational registry-based study (...) of closed claims against gastroenterologists involved in endoscopic perforations.We analyzed 175 closed claims related to perforations, all of which involved allegations of improper performance of the endoscopic procedure. Inadequate communication (n = 71, 41%) and clinical judgment (n = 60, 34%) on the part of the endoscopists were observed. Inadequate communication and clinical judgment were associated with over 3-fold odds of indemnity payment (odds ratio [OR] 3.31; 95% confidence interval [CI], 1.46

2020 American Journal of Gastroenterology

136. Affective Processing Biases in Relation to Past, Current, and Future Depression in Children and Adolescents. (Abstract)

emerged, mirroring the broader AGN literature. In primary analyses, group by valence interactions were only observed at one AGN administration; none replicated across administrations. Similarly, in regression analyses depressive symptoms had no relation to affective processing biases/deficits at AGN Time 1, though some relationships were detected between symptoms and AGN Time 2.Relatively few youth met criteria for a depressive disorder, though analyses were appropriately powered and supplemental (...) Affective Processing Biases in Relation to Past, Current, and Future Depression in Children and Adolescents. The affective go/no-go (AGN) task has been used to assess affective biases in attention set-shifting and deficits in inhibitory control of emotional information among depressed youth, but results have been inconsistent. We aimed to test AGN robustness and clarify temporal relationships between depressive symptoms and affective processing in youth.We evaluated AGN performance twice (Time

2020 Journal of Affective Disorders

137. Night shift work in resident physicians: does it affect mood states and cognitive levels? (Abstract)

Night shift work in resident physicians: does it affect mood states and cognitive levels? The effects of night shift work on health status have been widely studied. Night workers seem to smoke more, eat badly and show a low propensity to physical activity. Night work can be associated with an increase in cardiovascular and gastrointestinal disorders, alterations in immune response, diabetes, aging, hormonal imbalance, and premature death; alteration of circadian rhythm is also regarded (...) and services, and an increase slightly beyond the physiological levels of the T-score 50 of Fatigue-Inertia (F) always in the same groups. An increase in the Vigour-Activity (V) value beyond T-score 50 levels was also observed among residents of all the areas considered.Emotional involvement could be attributed to the gap between high professional demand and lack of experience and knowledge among trainees. Tutors should help their students in order to identify earlier changes in the mood. Improvement

2020 Journal of Affective Disorders

138. Suicidal ideation and affect lability in single and multiple suicidal attempters with Major Depressive Disorder: An exploratory network analysis. (Abstract)

Suicidal ideation and affect lability in single and multiple suicidal attempters with Major Depressive Disorder: An exploratory network analysis. A better understanding of the specific contribution of risk factors to suicidal behavior could arise from analyzing suicidal ideation (SI) in clinical samples, and comparing single versus multiple suicide attempters through contemporary methods allowing complex and dynamical analyses of multiple and simultaneously interacting suicide risk factors.We (...) explored associations among suicidal ideation (SI), affect lability and other suicide risk factors in 323 suicidal attempters diagnosed with major depressive disorder (MDD). We analyzed the network structure and centrality of the total sample, and compared single versus multiple attempters and subjects with low and high suicidal ideation.SI was connected with anxiety (trait) and hopelessness. Central nodes for global and specific groups were affect lability (from anxiety to depression), anxiety

2020 Journal of Affective Disorders

139. Early life exposure to coal mine fire and tobacco smoke affect subclinical vascular function. (Abstract)

Early life exposure to coal mine fire and tobacco smoke affect subclinical vascular function. To evaluate whether vascular health in young children was associated with exposure to a 6-week episode of coal mine fire smoke or environmental tobacco smoke (ETS) in a retrospective cohort study.Three years after a coal mine fire in Victoria, Australia, we investigated the vascular health of children either in utero (n=75) or aged <2 years (postnatal exposure, n=96) at the time of the fire (...) positively associated with PWV (β=0.116, p=0.028). When these two groups were combined, there was an association between mean PM2.5 and increased PWV in those children who had ETS exposure (β=0.148, p=0.033) or whose mothers smoked (β=0.151, p=0.011), but not in those not exposed to ETS or maternal smoking.Three years after a coal mine fire, infants aged up to 2 years at the time of exposure have increases in vascular stiffness. Although no adverse effects were observed in the in uterus exposure group

2020 Archives of Disease in Childhood

140. Mutations identified in the HCV polymerase of ribavirin treated chronic hepatitis C patients cause resistance and affect viral replication fidelity. (Abstract)

Mutations identified in the HCV polymerase of ribavirin treated chronic hepatitis C patients cause resistance and affect viral replication fidelity. Ribavirin has been used to treat patients with chronic hepatitis C virus (HCV) infection for 25 years, however, its antiviral mechanism of action remains unclear. Here we studied virus evolution in a subset of samples from a randomized 24-week trial of ribavirin monotherapy versus placebo in chronic HCV patients, as well as the viral resistance (...) mechanisms of the observed ribavirin-associated mutations in cell-culture. Thus, we performed next generation sequencing of the full-length coding sequences of HCV recovered from patients at weeks 0, 12, 20, 32 and 40 and analyzed novel single nucleotide polymorphisms (SNPs), diversity, and mutation-linkage. At week 20, increased genetic diversity was observed in 5 ribavirin- compared to 4 placebo-treated HCV patients due to new synonymous SNPs, particularly G-to-A and C-to-U ribavirin-associated

2020 Antimicrobial Agents and Chemotherapy

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