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Observed Affect

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121. Factors affecting Dupont´s lark distribution and range regression in Spain. (Full text)

Factors affecting Dupont´s lark distribution and range regression in Spain. In this work, we analyse factors explaining the distribution and range regression of Dupont's lark in Spain, the only European country in which this threatened alaudid is present. Dupont's lark is an extremely elusive and scarce species, distributed across a reduced and strongly fragmented range, showing a metapopulational structure with unknown dispersive and connective mechanisms. We used maximum entropy modelling (...) (Maxent) on nearly 15,000 Dupont's lark observations (1985-2015) to assess the probability of presence at a 1 km resolution across its European range. Moreover, we tested the probability of extinction by comparing pre- and post-2000 observations by means of a GLM over a subset of cells with presence-absence data. We obtained strong model fitting (AUC = 0.919), in which species occurrence was explained by low values of plant productivity (NDVI), climate (high temperature range and medium annual

2019 PLoS ONE PubMed abstract

122. The costs of negative affect attributable to alcohol consumption in later life: A within-between random longitudinal econometric model using UK Biobank. (Full text)

alcohol's detriment to affect was derived.A consistent relationship between depression and alcohol consumption (β = 0.001, z = 7.64) and neuroticism and alcohol consumption (β = 0.001, z = 9.24) was observed in cross-sectional analyses, replicated in within-between models (depression β = 0.001, z = 2.32; neuroticism β = 0.001, z = 2.33). Significant associations were found between household income and depression (cross sectional β = -0.157, z = -23.86, within-between β = -0.146, z = -9.51) and household (...) The costs of negative affect attributable to alcohol consumption in later life: A within-between random longitudinal econometric model using UK Biobank. Research demonstrates a negative relationship between alcohol use and affect, but the value of deprecation is unknown and thus cannot be included in estimates of the cost of alcohol to society. This paper aims to examine this relationship and develop econometric techniques to value the loss in affect attributable to alcohol consumption.Cross

2019 PLoS ONE PubMed abstract

123. Perinatal outcomes of twin pregnancies affected by early twin-twin transfusion syndrome: A systematic review and meta-analysis. (Abstract)

occlusion because of insufficient sample and lack of reporting of most of the observed outcomes. Overall, the incidence of perinatal death was 43.9% (95% CI 5.9-87.7) in twins managed expectantly, 47.3% (95% CI 21.4-70.0) in those treated with laser and 28.5% in those who had amnioreduction.Twin pregnancies affected by early TTTS are at substantial risk of perinatal mortality and morbidity; however, the data come from very small studies with a high risk of selection bias.© 2020 Nordic Federation (...) Perinatal outcomes of twin pregnancies affected by early twin-twin transfusion syndrome: A systematic review and meta-analysis. Twin-to-twin transfusion syndrome (TTTS) is associated with a high risk of perinatal mortality and morbidity if not treated. However, the optimal timing and management in case of early (occurring < 18 weeks) TTTS has not been established yet.This is a systematic review and meta-analysis aiming at evaluating the outcomes of monochorionic diamniotic twin pregnancies

2020 Acta Obstetricia et Gynecologica Scandinavica

124. Does Iodinated Contrast Affect Residual Renal Function in Dialysis Patients? A Systematic Review and Meta-Analysis. (Abstract)

Does Iodinated Contrast Affect Residual Renal Function in Dialysis Patients? A Systematic Review and Meta-Analysis. It is important for medical practitioners to be aware of the effect of iodinated contrast media on the residual renal function (RRF) of dialysis patients who require diagnostic or therapeutic imaging procedures. Preservation of RRF is important given that it is a robust predictor of higher survival. However, the absence of any effect would allow for easier diagnostic (...) , hospitalization following contrast administration, and all-cause mortality.Nine studies including 434 patients met the inclusion criteria. A meta-analysis was performed on 7 trials with complete quantitative data. The weighted difference in means was -0.16 mL/min (95% confidence interval -0.66 to 0.34 mL/min; p = 0.53), suggesting a small reduction in residual function following contrast administration. Significant heterogeneity in the data was observed, with a Cochran Q of 35.83 and an I2 of 83.25 (p

2020 Nephron

125. Nitric Oxide and a Conditioned Medium Affect the Hematopoietic Development in a Microfluidic Mouse Embryonic Stem Cell/OP9 Co-Cultivation System (Full text)

Nitric Oxide and a Conditioned Medium Affect the Hematopoietic Development in a Microfluidic Mouse Embryonic Stem Cell/OP9 Co-Cultivation System A microfluidic co-culture system, consisting of mouse embryonic stem cells (mESCs)/OP9 cells, was evaluated as a platform for studying hematopoietic differentiation mechanisms in vitro. mESC differentiation into blood cells was achieved in a microchannel that had the minimum size necessary to culture cells. The number of generated blood cells increased (...) or decreased based on the nitric oxide (NO) donor or inhibitor used. Conditioned medium from OP9 cell cultures also promoted an increase in the number of blood cells. The number of generated blood cells under normal medium flow conditions was lower than that observed under the static condition. However, when using a conditioned medium, the number of generated blood cells under flow conditions was the same as that observed under the static condition. We conclude that secreted molecules from OP9 cells have

2020 Micromachines PubMed abstract

126. Can dietary viscous fiber affect body weight independently of an energy-restrictive diet? A systematic review and meta-analysis of randomized controlled trials. (Abstract)

Can dietary viscous fiber affect body weight independently of an energy-restrictive diet? A systematic review and meta-analysis of randomized controlled trials. The role of dietary fiber in obesity management remains debatable. Evidence suggests that intake of viscous fiber may have the potential to facilitate weight loss.We aimed to summarize and quantify the effects of viscous fiber on body weight, BMI, waist circumference, and body fat, independent of calorie restriction, through (...) % CI: -1.56%, 0.00%; P = 0.05) when consumed with an ad libitum diet. Greater reductions in body weight were observed in overweight individuals and those with diabetes and metabolic syndrome. The certainty of evidence was graded moderate for body weight, high for waist circumference and body fat, and low for BMI.Dietary viscous fiber modestly yet significantly improved body weight and other parameters of adiposity independently of calorie restriction. Future trials are warranted to address

2020 The American journal of clinical nutrition

127. Factors affecting utilization of antenatal care in Ethiopia: A systematic review and meta-analysis. (Full text)

Factors affecting utilization of antenatal care in Ethiopia: A systematic review and meta-analysis. In the context of high maternal morbidity and mortality in Sub-Saharan Africa, less than 80% of pregnant women receive antenatal care services. According to a 2016 national report, only 62% of pregnant women in Ethiopia made at least one antenatal care visit. The aim of this review was to systematically and quantitatively summarize the factors affecting utilization of antenatal care (...) in Ethiopia.We searched PubMed, Medline, EMBASE, CINAHL, Google Scholar and Maternity and Infant Care database for studies that had been conducted in Ethiopia between 2002 and 2016. We summarized the studies on the use of antenatal care services quantitatively and qualitatively. A random-effects model was conducted to obtain the pooled estimates.A total of fifteen observational studies were included in this review. The pooled prevalence of utilization of antenatal care services in Ethiopia was 63.77% (95CI

2019 PLoS ONE PubMed abstract

128. Does Islamic fasting affect cognitive functions in adolescents? A systematic review. (Abstract)

Does Islamic fasting affect cognitive functions in adolescents? A systematic review. A considerable population of the Muslim community is made up of youngsters who observe fast during the month of Ramadan. There are other activities in Ramadan that the adolescents might be involved in, such as education in which one's proper cognitive activity is necessary. The current systematic review was planned to evaluate the relationship between Islamic fasting and cognitive activities. A number (...) of studies have paid attention to the brain structure and scope of cognitive changes during fasting. Islamic fasting may affect cognitive activities such as spatial memory, visual memory and attention that play an important role in effective education. It is suggested to conduct a study with a larger sample size, using similar evaluation tools, targeting different cognitive tasks.

2020 JPMA. The Journal of the Pakistan Medical Association

129. Isoprene is more affected by climate drivers than monoterpenes: A meta-analytic review on plant isoprenoid emissions. (Abstract)

Isoprene is more affected by climate drivers than monoterpenes: A meta-analytic review on plant isoprenoid emissions. Isoprene and monoterpenes (MTs) are among the most abundant and reactive volatile organic compounds produced by plants (biogenic volatile organic compounds). We conducted a meta-analysis to quantify the mean effect of environmental factors associated to climate change (warming, drought, elevated CO2 , and O3 ) on the emission of isoprene and MTs. Results indicated that all (...) by warming (+39%) and by elevated O3 (limited to O3 -insensitive plants, and evergreen species with storage organs). Our results clearly highlight individual effects of environmental factors on isoprene and MT emissions, and an overall uncoupling between these secondary metabolites produced by the same methylerythritol 4-phosphate pathway. Future results from manipulative experiments and long-term observations may help untangling the interactive effects of these factors and filling gaps featured

2020 Plant, cell & environment

130. Do anti-tumour necrosis factor-α biologics affect subclinical measures of atherosclerosis and arteriosclerosis? A systematic review. (Abstract)

Do anti-tumour necrosis factor-α biologics affect subclinical measures of atherosclerosis and arteriosclerosis? A systematic review. Inflammatory cytokines, particularly tumour necrosis factor-α (TNFα), are thought to promote arterial disease through a variety of mechanisms leading to arteriosclerosis and atherosclerosis. We reviewed the existing evidence of the effect of anti-TNFα treatment on arteriosclerosis and atherosclerosis in chronic inflammatory disease.We performed a systematic (...) in patients receiving anti-TNFα therapy for a clinical indication (usually an inflammatory disease such as an inflammatory arthritis, psoriasis or inflammatory bowel disease). Of these, only 6 were randomised clinical controlled trials. Whilst many observational studies and noncontrolled studies reported positive findings, positive finding were reported in only 1 of 6 randomised clinical controlled trials.There is no strong evidence for an effect of anti-TNFα biologics on the subclinical measures

2020 British journal of clinical pharmacology

131. Density-dependent space use affects interpretation of camera trap detection rates. (Full text)

Density-dependent space use affects interpretation of camera trap detection rates. Camera traps (CTs) are an increasingly popular tool for wildlife survey and monitoring. Estimating relative abundance in unmarked species is often done using detection rate as an index of relative abundance, which assumes that detection rate has a positive linear relationship with true abundance. This assumption may be violated if movement behavior varies with density, but the degree to which movement behavior (...) rates should be aware that observed differences may be biased low relative to true changes in abundance. Further information on animal movement, or methods that do not depend on assumptions of density-independent movement, may be required to make robust inferences on population trends.© 2019 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd.

2020 Ecology and evolution PubMed abstract

132. Positive affect and chronic pain: a preregistered systematic review and meta-analysis. (Abstract)

Positive affect and chronic pain: a preregistered systematic review and meta-analysis. Chronic noncancer pain (CNCP) is a significant health burden among adults. Standard behavioral therapies typically focus on targeting negative affect (NA) and yield only modest treatment effects. The aims of this study were to systematically review and investigate the association between positive affect (PA) and pain severity among adults with CNCP. Databases that were searched included MEDLINE (PubMed (...) ), PsycINFO, CINAHL, ProQuest Dissertations and Theses, OLASTER, Open Grey, and PsyArXiv (inception to July 23, 2019). We analyzed studies that: (1) used observational, experimental, or intervention study designs; (2) enrolled individuals with CNCP (pain ≥ 12 weeks); and (3) reported full quantitative results on outcomes. Two researchers independently screened articles, extracted data, and assessed the risk of bias. The main meta-analysis was followed by subgroup analyses. All analyses were performed

2020 Pain

133. Parent cognitive, behavioural, and affective factors and their relation to child pain and functioning in pediatric chronic pain: a systematic review and meta-analysis. (Abstract)

Parent cognitive, behavioural, and affective factors and their relation to child pain and functioning in pediatric chronic pain: a systematic review and meta-analysis. Previous studies have demonstrated that parental cognitive, behavioral, and emotional factors are related to child functioning in children and adolescents with chronic pain. This is particularly important to understand how to potentially enhance the efficacy of psychological interventions for children by incorporating (...) interventions targeting parents. We conducted a systematic review and meta-analysis to identify the specific parent factors that have been examined in the literature and to quantify the associations observed between parent factors and child pain and disability. A search of the electronic databases EMBASE, PsychINFO, Medline, and PubMed was conducted, using search terms related to chronic pain, pediatric population, and parents. Fifty-four studies met criteria and were included in the review. Parent pain

2020 Pain

134. Radiologically Defined Sarcopenia Affects Survival in Head and Neck Cancer: A Meta-Analysis. (Abstract)

Radiologically Defined Sarcopenia Affects Survival in Head and Neck Cancer: A Meta-Analysis. To determine whether radiologically defined sarcopenia at the C3 or L3 level as measured by computed tomography or magnetic resonance imaging is prognostic of overall survival (OS) in head and neck cancers (HNCs).Literature searches of PubMed, Embase, and Scopus were conducted on July 12, 2019, to include articles written in the English language with no constraints on publication date. To be included (...) Of Observational Studies in Epidemiology Checklist guidelines were used for reporting. Study quality assessment was performed using Quality In Prognosis Studies tool. The random-effects DerSimonian and Laird method was used for meta-analysis.Ten articles, nine retrospective and one prospective, were included in this meta-analysis (n = 2,181 patients). Significant differences were found in OS for HNC patients with sarcopenia (HR = 1.98; 95% CI: 1.64-2.39; P < .00001). No heterogeneity was detected in either

2020 The Laryngoscope

135. The Cerebellar Cognitive Affective Syndrome-a Meta-analysis. (Full text)

The Cerebellar Cognitive Affective Syndrome-a Meta-analysis. The cerebellar cognitive affective syndrome (CCAS) was first described by Schmahmann and Sherman in 1998. Despite their clear depiction of the syndrome, it is our experience that the CCAS has not yet found solid ground as a disease entity in routine clinical practice. This made us question the dimension of the CCAS in cerebellar patients. We performed a systematic review of the literature according to the PRISMA guidelines, in order (...) to answer the question whether patients with acquired isolated cerebellar lesions perform significantly worse on neuropsychological testing compared to healthy controls. Studies were selected based on the predefined eligibility criteria and quality assessment. The systematic search resulted in ten studies, mainly observational cohorts consecutively including adult patients with isolated cerebellar lesions. Patients were compared to healthy controls, and neuropsychological investigation was done within

2020 Cerebellum (London, England) PubMed abstract

136. The relationship between trait mindfulness and affective symptoms: A meta-analysis of the Five Facet Mindfulness Questionnaire (FFMQ). (Abstract)

Questionnaire. A comprehensive search yielded 148 eligible studies, comprising 157 distinct samples and 44,075 participants. The weighted mean correlation for affective symptoms and overall trait mindfulness was r = -0.53. Among mindfulness facets, Nonjudge (r = -0.48) and Act with Awareness (r = -0.47) demonstrated the largest correlations, followed by Nonreact (r = -0.33) and Describe (r = -0.29). Observe was not significantly correlated with affective symptoms. No significant differences in the strength (...) The relationship between trait mindfulness and affective symptoms: A meta-analysis of the Five Facet Mindfulness Questionnaire (FFMQ). Trait mindfulness appears to be related to lower levels of negative affective symptoms, but it remains uncertain which facets of mindfulness are most important in this relationship. Accordingly, the present meta-analysis examined studies reporting correlations between affective symptoms and trait mindfulness as assessed by the Five Facet Mindfulness

2020 Clinical psychology review

137. How does comorbid bronchiectasis affect asthmatic patients? A meta-analysis. (Abstract)

How does comorbid bronchiectasis affect asthmatic patients? A meta-analysis. Asthma and bronchiectasis are known to be two distinct diseases with different etiology, pathophysiology, management and prognosis. However, a high prevalence of bronchiectasis has been reported in patients with severe asthma. Thus, it is of great importance to identify the impact of bronchiectasis on asthmatic patients.Databases including PubMed, Embase, Cochrane, Web of Science were searched comprehensively (...) to identify relevant human clinical studies published until February 2020.Two investigators(Gelei Lan, Guochao Shi) independently obtained the potentially eligible articles based on their titles and abstracts. When opinions differed between the investigators, discussions were made to reach an agreement. The authors of the included studies were contacted for inquiry when necessary.Six observational studies with 1004 patients were included in the meta-analysis. The mean prevalence of bronchiectasis

2020 Journal of Asthma

138. Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis. (Full text)

Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis. Primary sclerosing cholangitis (PSC) is characterized by chronic cholestasis and inflammation, which promotes cirrhosis and an increased risk of cholangiocellular carcinoma (CCA). The transcription factor Krueppel-like-factor-6 (KLF6) is a mediator of liver regeneration, steatosis, and hepatocellular carcinoma (HCC), but no data is yet available on its potential role in cholestasis. Here (...) -overexpressing HepG2 cells were used to analyze the interaction of KLF6 and FXR target genes such as NR0B2.Based on IHC, PSC patients could be subdivided into two groups showing either low (<80%) or high (>80%) hepatocellular KLF6 expression. In patients with high KLF6 expression, we observed a superior survival in Kaplan-Meier analysis. Klf6-knockout mice showed reduced hepatic necrosis following BDL when compared to controls. KLF6 suppressed NR0B2 expression in HepG2 cells mediated through binding of KLF6

2020 Liver International PubMed abstract

139. Factors That Affect Adequacy of Colon Cleansing for Colonoscopy in Hospitalized Patients. (Abstract)

Factors That Affect Adequacy of Colon Cleansing for Colonoscopy in Hospitalized Patients. Hospitalization is associated with inadequate colon cleansing before colonoscopy. We aimed to identify factors associated to inadequate colon cleansing among inpatients, and to derive and validate a model to identify inpatients with inadequate cleansing.We performed a prospective observational study at 12 hospitals in Italy. Consecutive adult inpatients scheduled for colonoscopy for any indication were (...) -statistic, 0.78 (95% CI, 0.74-0.81) for the discrimination cohort and c-statistic, 0.73 (95% CI, 0.69-0.78) for the validation cohort. We developed app for use by clinicians.In a prospective observational study, we identified setting-, patient- and preparation-related factors that affect colon cleansing among inpatients. We derived and validated a model to identify patients with inadequate preparation and developed an app for clinicians. ClinicalTrials.gov no: NCT03925506.Copyright © 2020 AGA Institute

2020 Clinical Gastroenterology and Hepatology

140. Factors affecting dislocation after bipolar hemiarthroplasty in patients with femoral neck fracture. (Abstract)

Factors affecting dislocation after bipolar hemiarthroplasty in patients with femoral neck fracture. This study aimed to investigate the anatomic risk factors associated with dislocation following bipolar hemiarthroplasty for the treatment of femoral neck fracture.We retrospectively reviewed 208 consecutive patients (133 women, 75 men) with femoral neck fractures who were treated with bipolar hemiarthroplasty between 2015 and 2018. A comparative analysis was performed between dislocation (n (...)  = 18) and non-dislocation (n = 190) groups in terms of patient demographics, surgical and pelvic morphologic factors, and clinical outcomes, including postoperative Harris and modified Harris hip scores. Independent risk factors affecting dislocation were also evaluated.The mean follow-up period was 30.8 ± 2.0 (range, 12-48) months. The mean age was 79.2 ± 7.4 (range, 71-94) years. The dislocation rate was 8.6% (18/208), and the mean dislocation time after operation was 2.0 ± 1.1 (range, 1-4

2020 Injury

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