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Observed Affect

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81. The Validation of Macro and Micro Observations of Parent–Child Dynamics Using the Relationship Affect Coding System in Early Childhood Full Text available with Trip Pro

The Validation of Macro and Micro Observations of Parent–Child Dynamics Using the Relationship Affect Coding System in Early Childhood This study examined the validity of micro social observations and macro ratings of parent-child interaction in early to middle childhood. Seven hundred and thirty-one families representing multiple ethnic groups were recruited and screened as at risk in the context of Women, Infant, and Children (WIC) Nutritional Supplement service settings. Families were (...) randomly assigned to the Family Checkup (FCU) intervention or the control condition at age 2 and videotaped in structured interactions in the home at ages 2, 3, 4, and 5. Parent-child interaction videotapes were micro-coded using the Relationship Affect Coding System (RACS) that captures the duration of two mutual dyadic states: positive engagement and coercion. Macro ratings of parenting skills were collected after coding the videotapes to assess parent use of positive behavior support and limit

2017 Prevention science : the official journal of the Society for Prevention Research Controlled trial quality: uncertain

82. International prospective observational study of upper gastrointestinal haemorrhage: Does weekend admission affect outcome? Full Text available with Trip Pro

International prospective observational study of upper gastrointestinal haemorrhage: Does weekend admission affect outcome? Out of hours admissions have higher mortality for many conditions but upper gastrointestinal haemorrhage studies have produced variable outcomes.Prospective study of 12 months consecutive admissions of upper gastrointestinal haemorrhage from four international high volume centres. Admission period (weekdays, weeknights or weekends), demographics, haemodynamic parameters

2017 United European gastroenterology journal

83. Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions? Observations and introspection of the bioanalysis Full Text available with Trip Pro

Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions? Observations and introspection of the bioanalysis 28461740 2018 07 17 2018 12 02 1177-8881 11 2017 Drug design, development and therapy Drug Des Devel Ther Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug (...) interactions? Observations and introspection of the bioanalysis. 1263-1265 10.2147/DDDT.S137116 Thakkar Disha D Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India. Dash Ranjeet Prasad RP Drug Metabolism and Pharmacokinetics, Johns Hopkins Drug Discovery Program, Johns Hopkins University. Department of Neurology, Johns Hopkins University, Baltimore, MD, USA. eng Journal Article 2017 04 20 New Zealand Drug Des Devel Ther

2017 Drug design, development and therapy

84. Observing Third-Party Attentional Relationships Affects Infants' Gaze Following: An Eye-Tracking Study Full Text available with Trip Pro

Observing Third-Party Attentional Relationships Affects Infants' Gaze Following: An Eye-Tracking Study Not only responding to direct social actions toward themselves, infants also pay attention to relevant information from third-party interactions. However, it is unclear whether and how infants recognize the structure of these interactions. The current study aimed to investigate how infants' observation of third-party attentional relationships influence their subsequent gaze following. Nine (...) -month-old, 1-year-old, and 1.5-year-old infants (N = 72, 37 girls) observed video clips in which a female actor gazed at one of two toys after she and her partner either silently faced each other (face-to-face condition) or looked in opposite directions (back-to-back condition). An eye tracker was used to record the infants' looking behavior (e.g., looking time, looking frequency). The analyses revealed that younger infants followed the actor's gaze toward the target object in both conditions

2017 Frontiers in psychology

85. Current desires of conspecific observers affect cache-protection strategies in California scrub-jays and Eurasian jays Full Text available with Trip Pro

Current desires of conspecific observers affect cache-protection strategies in California scrub-jays and Eurasian jays Many corvid species accurately remember the locations where they have seen others cache food, allowing them to pilfer these caches efficiently once the cachers have left the scene [1]. To protect their caches, corvids employ a suite of different cache-protection strategies that limit the observers' visual or acoustic access to the cache site [2,3]. In cases where an observer's (...) sensory access cannot be reduced it has been suggested that cachers might be able to minimise the risk of pilfering if they avoid caching food the observer is most motivated to pilfer [4]. In the wild, corvids have been reported to pilfer others' caches as soon as possible after the caching event [5], such that the cacher might benefit from adjusting its caching behaviour according to the observer's current desire. In the current study, observers pilfered according to their current desire

2017 Current Biology

86. The hypospadias classification affected the surgical outcomes of staged oral mucosa graft urethroplasty in hypospadias reoperation: An observational study. Full Text available with Trip Pro

The hypospadias classification affected the surgical outcomes of staged oral mucosa graft urethroplasty in hypospadias reoperation: An observational study. The staged graft urethroplasty is a recommended technique for repairing complex hypospadias. This retrospective study aimed to investigate the outcomes of this technique in hypospadias patients undergoing reoperation and to analyze the underlying contributing factors including age, meatus location, and graft and suture type.We (...) graft urethroplasty is an effective technique in reoperative hypospadias repairs with reasonable complication risk. The hypospadias classification affects the surgical outcomes.Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.

2017 Medicine

87. Aging and a genetic KIBRA polymorphism interactively affect feedback- and observation-based probabilistic classification learning. Full Text available with Trip Pro

Aging and a genetic KIBRA polymorphism interactively affect feedback- and observation-based probabilistic classification learning. Probabilistic category learning involves complex interactions between the hippocampus and striatum that may depend on whether acquisition occurs via feedback or observation. Little is known about how healthy aging affects these processes. We tested whether age-related behavioral differences in probabilistic category learning from feedback or observation depend (...) on a genetic factor known to influence individual differences in hippocampal function, the KIBRA gene (single nucleotide polymorphism rs17070145). Results showed comparable age-related performance impairments in observational as well as feedback-based learning. Moreover, genetic analyses indicated an age-related interactive effect of KIBRA on learning: among older adults, the beneficial T-allele was positively associated with learning from feedback, but negatively with learning from observation. In younger

2017 Neurobiology of Aging

88. Workload even affects hand hygiene in a highly trained and well-staffed setting: a prospective 365/7/24 observational study. (Abstract)

Workload even affects hand hygiene in a highly trained and well-staffed setting: a prospective 365/7/24 observational study. Compliance with hand hygiene (HH) has often not proved satisfactory; high workload is a commonly self-reported reason. Previous studies comparing workload and compliance have not measured workload precisely and have focused on certain times of day. This study aimed to investigate the association between HH compliance and workload, both electronically defined 365/7/24 (...) (primary endpoint). In addition, the quality of commonly used compliance defining methods (hand disinfectant usage, direct observation) was investigated (secondary endpoint).Correlation of electronically measured HH compliance (hand-rub activities (HRA)/HH opportunities) with electronically determined workload (nursing time output/nursing time input) was undertaken over one year at a stem cell transplant unit at University Hospital Basel, Switzerland. HRA and procedures requiring HRA according

2017 Journal of Hospital Infection

89. Evaluation of IL-12RB1, IL-12B, CXCR-3 and IL-17a expression in cases affected by a non-healing form of cutaneous leishmaniasis: an observational study design. Full Text available with Trip Pro

Evaluation of IL-12RB1, IL-12B, CXCR-3 and IL-17a expression in cases affected by a non-healing form of cutaneous leishmaniasis: an observational study design. Seldom cutaneous leishmaniasis (CL) may present as a lasting and active lesion(s), known as a non-healing form of CL (NHCL). Non-functional type 1 T helper (Th1) cells are assumed the most important factor in the outcome of the disease. The present study aims to assess some molecular defects that potentially contribute to Th1 impairment (...) in NHCL.This prospective observational study will be implemented among five groups. The first and second groups comprise patients afflicted with non-healing and healing forms of CL, respectively. The third group consists of those recovered participants who have scars as a result of CL. Those participants who have never lived or travelled to endemic areas of leishmaniasis will comprise the fourth group. The fifth group comprises participants living in hyperendemic areas for leishmaniasis, although none

2017 BMJ open

90. Outcome of day treatment for older adults with affective disorders: An observational pre-post design of two transdiagnostic approaches. (Abstract)

Outcome of day treatment for older adults with affective disorders: An observational pre-post design of two transdiagnostic approaches. First, to evaluate the outcome of 2 transdiagnostic day treatment programs. A 20-week psychotherapeutic day treatment (PDT) and an activating day treatment (ADT) program delivered in blocks of 4 weeks with a maximum of 24 weeks with respect to depression, anxiety, and hypochondriasis. Second, to explore the impact of cognitive impairment and personality (...) nor ADT. Cognitive impairment negatively interfered with the course of depressive symptoms among patients receiving PDT.Transdiagnostic day treatment is promising for older adults with affective disorders with high feasibility.Copyright © 2017 John Wiley & Sons, Ltd.

2017 International Journal of Geriatric Psychiatry

91. Factors affecting the course and severity of adult acne. Observational cohort study. (Abstract)

Factors affecting the course and severity of adult acne. Observational cohort study. To identify factors improving symptoms and shortening duration of AA.The observational cohort study was performed in 111 patients with AA (>25 y.o.) in 2015-2016. Clinical manifestation, previous treatments, environmental risk factors and features of juvenile acne affecting AA were assessed.The maximum severity of persistent acne was significantly lower after 25 years of age, as compared to adolescence (7.2 vs

2017 Journal of Dermatological Treatment

92. Factors affecting seizure outcome after epilepsy surgery: an observational series. Full Text available with Trip Pro

Factors affecting seizure outcome after epilepsy surgery: an observational series. Surgical treatment can bring seizure remission in people with focal epilepsy but requires careful selection of candidates.To determine which preoperative factors are associated with postoperative seizure outcome.We audited seizure outcome of 693 adults who had resective epilepsy surgery between 1990 and 2010 and used survival analysis to detect preoperatively identifiable risk factors of poor seizure

2017 Neurosurgery and Psychiatry

93. Maternal mental health and its influence on infant growth and development: A systematic review of observational studies in South and East Asia Full Text available with Trip Pro

Maternal mental health and its influence on infant growth and development: A systematic review of observational studies in South and East Asia Maternal mental health and its influence on infant growth and development: A systematic review of observational studies in South and East Asia Venkatesh S, Vindhya J, Nath A - Indian J Health Sci Biomed Res Maternal mental stress during pregnancy is an important public health concern. There is strong evidence from the Western world to support (...) of observational studies in South and East Asia , , Public Health Foundation of India, Indian Institute of Public Health, Hyderabad-Bangalore Campus, Bengaluru, Karnataka, India Date of Web Publication 4-Jun-2019 Correspondence Address : Dr. Anita Nath Public Health Foundation of India, Indian Institute of Public Health, Hyderabad-Bangalore Campus, 1 st Cross Magadi Road, Bengaluru - 560 023, Karnataka India Source of Support: None, Conflict of Interest: None DOI: 10.4103/kleuhsj.kleuhsj_9_19 Abstract Maternal

2019 Indian Journal of Health Sciences and Biomedical Research (KLEU)

94. Role of Candida infection in the malignant transformation of oral leukoplakia: A systematic review of observational studies Full Text available with Trip Pro

Role of Candida infection in the malignant transformation of oral leukoplakia: A systematic review of observational studies Role of Candida infection in the malignant transformation of oral leukoplakia: A systematic review of observational studies - Khilan Shukla, Ida Vun, Ivan Lov, George Laparidis, Caitlin McCamley, Anura Ariyawardana, 2019 Intended for healthcare professionals Cookies Notification This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies (...) : A systematic review of observational studies .entryAuthor" data-author-container-selector=".NLM_contrib-group"> Show all authors 1 Division of Tropical Health and Medicine, College of Medicine and Dentistry, James Cook University, Smithfield, QLD, Australia by this author for this author , 1 Division of Tropical Health and Medicine, College of Medicine and Dentistry, James Cook University, Smithfield, QLD, Australia by this author for this author , 1 Division of Tropical Health and Medicine, College

2019 Translational Research in Oral Oncology

95. Sialanar (glycopyrronium) - for treating severe drooling of saliva in children and adolescents (aged 3 years and above) with conditions affecting the nervous system, such as cerebral palsy, epilepsy and neurodegenerative diseases

Sialanar (glycopyrronium) - for treating severe drooling of saliva in children and adolescents (aged 3 years and above) with conditions affecting the nervous system, such as cerebral palsy, epilepsy and neurodegenerative diseases 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact 21 July 2016 EMA/555265/2016 Committee (...) apparent terminal elimination half-life TEAE treatment-emergent adverse event t.i.d three times daily T max time to maximum observed plasma concentration TSE transmissible spongiform encephalopathies UK United Kingdom ULN upper limit of the normal range USP/NF United States Pharmacopoeia/National Formulary US United States UV Ultraviolet VAS visual analogue scale V ß volume of distribution in the elimination phase V ss volume of distribution at steady state WEU Well Established Use XRD X-Ray

2016 European Medicines Agency - EPARs

96. Sperm Chromatin Immaturity Observed in Short Abstinence Ejaculates Affects DNA Integrity and Longevity In Vitro Full Text available with Trip Pro

Sperm Chromatin Immaturity Observed in Short Abstinence Ejaculates Affects DNA Integrity and Longevity In Vitro The influence of ejaculatory abstinence (EA) on semen parameters and subsequent reproductive outcome is still debatable; hence understanding the impact of EA on sperm structural and functional integrity may provide a valuable information on predicting successful clinical outcome.To understand the influence of EA on sperm chromatin maturity, integrity, longevity and global methylation (...) status.This experimental prospective study included 76 ejaculates from 19 healthy volunteers who provided ejaculates after observing 1, 3, 5 and 7 days of abstinence. Sperm chromatin maturity, DNA integrity and global methylation status were assessed in the neat ejaculate. Sperm motility, DNA integrity and longevity were assessed in the processed fraction of the fresh and frozen-thawed ejaculates to determine their association with the length of EA.Spermatozoa from 1 day ejaculatory abstinence (EA-1

2016 PloS one

97. The Impact of Experience on Affective Responses during Action Observation Full Text available with Trip Pro

The Impact of Experience on Affective Responses during Action Observation Perceiving others in action elicits affective and aesthetic responses in observers. The present study investigates the extent to which these responses relate to an observer's general experience with observed movements. Facial electromyographic (EMG) responses were recorded in experienced dancers and non-dancers as they watched short videos of movements performed by professional ballet dancers. Responses were recorded from (...) the corrugator supercilii (CS) and zygomaticus major (ZM) muscles, both of which show engagement during the observation of affect-evoking stimuli. In the first part of the experiment, participants passively watched the videos while EMG data were recorded. In the second part, they explicitly rated how much they liked each movement. Results revealed a relationship between explicit affective judgments of the movements and facial muscle activation only among those participants who were experienced

2016 PloS one

98. Factors affecting the normality of channel outputs of channelized model observers: an investigation using realistic myocardial perfusion SPECT images Full Text available with Trip Pro

Factors affecting the normality of channel outputs of channelized model observers: an investigation using realistic myocardial perfusion SPECT images The channelized Hotelling observer (CHO) uses the first- and second-order statistics of channel outputs under both hypotheses to compute test statistics used in binary classification tasks. If these input data deviate from a multivariate normal (MVN) distribution, the classification performance will be suboptimal compared to an ideal observer

2016 Journal of Medical Imaging

99. Do Case Rates Affect Physicians' Clinical Practice in Radiation Oncology?: An Observational Study Full Text available with Trip Pro

Do Case Rates Affect Physicians' Clinical Practice in Radiation Oncology?: An Observational Study Case rate payments combined with utilization monitoring may have the potential to improve the quality of care by reducing over and under-treatment. Thus, a national managed care organization introduced case rate payments at one multi-site radiation oncology provider while maintaining only fee-for-service payments at others. This study examined whether the introduction of the payment method had (...) suggest that the introduction of case rate payments did not adversely affect the rate of guideline-based care at the provider examined. Additional research is needed to isolate the effect of the payment model and assess implications in other populations.

2016 PloS one

100. The Role of Cognitive and Affective Empathy in Spouses' Support Interactions: An Observational Study Full Text available with Trip Pro

The Role of Cognitive and Affective Empathy in Spouses' Support Interactions: An Observational Study The present study examined how support providers' empathic dispositions (dispositional perspective taking, empathic concern, and personal distress) as well as their situational empathic reactions (interaction-based perspective taking, empathic concern, and personal distress) relate to the provision of spousal support during observed support interactions. Forty-five committed couples provided (...) questionnaire data and participated in two ten-minute social support interactions designed to assess behaviors when partners are offering and soliciting social support. A video-review task was used to assess situational forms of perspective taking (e.g., empathic accuracy), empathic concern and personal distress. Data were analyzed by means of the multi-level Actor-Partner Interdependence Model. Results revealed that providers scoring higher on affective empathy (i.e., dispositional empathic concern

2016 PloS one

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