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Observed Affect

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1. Negative affectivity and social inhibition are associated with increased cardiac readmission in patients with heart failure: A preliminary observation study. Full Text available with Trip Pro

Negative affectivity and social inhibition are associated with increased cardiac readmission in patients with heart failure: A preliminary observation study. Type D personality was hypothesized to influence clinical and patient-centered outcomes patients with heart failure. The aim of this study was to investigate the association between negative affectivity and social inhibition components of Type D personality and cardiac readmission in patients with heart failure.A prospective observational (...) study design was used. A total of 222 patients with heart failure were recruited from the department of cardiology in two regional hospitals in Taiwan. The 14-item Type D Scale-Taiwanese version was used to assess negative affectivity and social inhibition of the patients. Logistic regression analyses were conducted to determine the association of both Z-score transformed and dichotomized negative affectivity and social inhibition with 6-month and 18-month cardiac readmissions.A total of 55 patients

2019 PLoS ONE

2. Co-occurrence of positive staff interactions and positive affect in memory-care residents: An observational study. (Abstract)

Co-occurrence of positive staff interactions and positive affect in memory-care residents: An observational study. With high numbers of persons with dementia living in residential care, it is vital to maximize psychosocial well-being for this population in this setting. The current study observed whether proportions of positive affect in residents differed based on co-occurring staff (typically certified nurse assistants) interaction types.A trained research team observed staff/resident (...) interactions and affect in residents with dementia in common areas of a residential memory care unit (n = 22; observations over one year, or 6999 minutes total).The most observed resident affect type was neutral (53.1% of all minutes observed), followed by positive affect (44.5%). The most common staff interaction type was neutral/no interaction (81.1% of all minutes observed), followed by positive staff interactions (18.1%). There was very little resident negative affect (2.4%) and staff negative

2020 International Journal of Geriatric Psychiatry

3. Does second EMS unit response time affect outcomes of OHCA in multi-tiered system? A nationwide observational study. (Abstract)

Does second EMS unit response time affect outcomes of OHCA in multi-tiered system? A nationwide observational study. The time dependence of a multi-tier response for out-of-hospital cardiac arrest (OHCA) is unclear. The aim of this study was to evaluate the time-dependent effect of EMS response type in a multi-tiered system on the clinical outcomes of OHCA.Adult EMS-treated OHCA of presumed cardiac etiology who were not witnessed by EMS between January 2015 and December 2017 were included

2020 American Journal of Emergency Medicine

4. Smoking status affects clinical characteristics and disease course of acute exacerbation of chronic obstructive pulmonary disease: A prospectively observational study. Full Text available with Trip Pro

Smoking status affects clinical characteristics and disease course of acute exacerbation of chronic obstructive pulmonary disease: A prospectively observational study. Existing studies primarily explored chronic obstructive pulmonary disease (COPD) in smokers, whereas the clinical characteristics and the disease course of passive or nonsmokers have been rarely described. In the present study, patients hospitalized and diagnosed as acute exacerbation of COPD (AECOPD) were recruited and followed

2020 Chronic respiratory disease

5. Did psychosocial status, sociodemographics and smoking status affect non-attendance in control participants in the Danish Lung Cancer Screening Trial? A nested observational study. Full Text available with Trip Pro

Did psychosocial status, sociodemographics and smoking status affect non-attendance in control participants in the Danish Lung Cancer Screening Trial? A nested observational study. We investigated if psychosocial status, sociodemographics and smoking status affected non-attendance in the control group in the randomised Danish Lung Cancer Screening Trial (DLCST).This study was an observational study nested in the DLCST. Due to large non-attendance in the control group in the second screening

2020 BMJ open

6. Hydromorphone Unit Dose Affects Intraoperative Dosing: An Observational Study. Full Text available with Trip Pro

Hydromorphone Unit Dose Affects Intraoperative Dosing: An Observational Study. Although clinical factors related to intraoperative opioid administration have been described, there is little research evaluating whether administration is influenced by drug formulation and, specifically, the unit dose of the drug. The authors hypothesized that the unit dose of hydromorphone is an independent determinant of the quantity of hydromorphone administered to patients intraoperatively.This observational (...) (risk ratio, 1.48; 95% CI, 1.11-1.98; P = 0.008).This observational study using an interrupted time series analysis demonstrates that unit dose of hydromorphone (2 mg vs. 1 mg) is an independent determinant of the quantity of hydromorphone administered to patients in the intraoperative period.

2020 Anesthesiology

7. Is bodyweight affecting plantar pressure distribution in children?: An observational study. Full Text available with Trip Pro

Is bodyweight affecting plantar pressure distribution in children?: An observational study. The aim of this study is twofold: firstly, to investigate the plantar pressure distribution differences in children coming from 4 different weight categories and secondly to analyze the presence of sex-related plantar pressure distribution differences.Overall, 416 children, aged 7 to 12 years old were randomly selected from 6 different local schools, and voluntarily participated in the study. Two hundred (...) among boys, revealed a different pattern of load distribution among (O) compared with other categories. This effect was not detected among women. Different profile of load distribution on the rearfoot and forefoot between boys and girls was found, with girls bearing significantly more weight in the right rearfoot compared with boys (P = .001).It can be concluded that the weight status of the children can affect the plantar load distribution, with obese category being different from (NW) and (OW

2020 Medicine

8. Duodenal major papilla morphology can affect biliary cannulation and complications during ERCP, an observational study. Full Text available with Trip Pro

Duodenal major papilla morphology can affect biliary cannulation and complications during ERCP, an observational study. We investigated whether duodenal major papilla morphology could be a risk factor for failure of selective biliary cannulation (SBC) and post endoscopic retrograde cholangiography and pancreatography (ERCP) complications.A prospectively recorded database was reviewed retrospectively. Patients were included if they received therapeutic ERCP and had naïve major duodenal papilla

2020 BMC Gastroenterology

9. How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies. Full Text available with Trip Pro

How unmeasured confounding in a competing risks setting can affect treatment effect estimates in observational studies. Analysis of competing risks is commonly achieved through a cause specific or a subdistribution framework using Cox or Fine & Gray models, respectively. The estimation of treatment effects in observational data is prone to unmeasured confounding which causes bias. There has been limited research into such biases in a competing risks framework.We designed simulations to examine (...) on the event-of-interest. The association between correlation and bias is reversed if the unmeasured confounder affects the competing event. These effects are reversed for the bias on the treatment effect of the competing event and are amplified when there are uneven treatment arms.The effect of unmeasured confounding on an event-of-interest or a competing event should not be overlooked in observational studies as strong correlations can lead to bias in treatment effect estimates and therefore cause

2019 BMC medical research methodology

10. Does deprivation affect the demand for NHS Direct? Observational study of routine data from Wales. Full Text available with Trip Pro

Does deprivation affect the demand for NHS Direct? Observational study of routine data from Wales. To estimate the effect of deprivation on the demand for calls to National Health Service Direct Wales (NHSDW) controlling for confounding factors.Study of routine data on over 400 000 calls to NHSDW using multiple regression to analyse the logarithms of ward-specific call rates across Wales by characteristics of call, patient and ward, notably the Welsh Index of Multiple Deprivation.810 electoral

2019 BMJ open

11. Observer-independent assessment of psoriasis affected area using machine learning. (Abstract)

Observer-independent assessment of psoriasis affected area using machine learning. Assessment of psoriasis severity is strongly observer-dependent and objective assessment tools are largely missing. The increasing number of patients receiving highly expensive therapies that are reimbursed only for moderate-to-severe psoriasis motivates the development of higher quality assessment tools.To establish an accurate and objective psoriasis assessment method based on segmenting images by machine (...) learning technology.In this retrospective, non-interventional, single-centered, interdisciplinary study of diagnostic accuracy 259 standardized photographs of Caucasian patients were assessed and typical psoriatic lesions were labelled. 203 of those were used to train and validate an assessment algorithm which was then tested on the remaining 56 photographs. The results of the algorithm assessment were compared with manually marked area, as well as with the affected area determined by trained

2019 Journal of the European Academy of Dermatology and Venereology

12. Individual and organizational factors that affect implementation of evidence-based practices for children with autism in public schools: a cross-sectional observational study. Full Text available with Trip Pro

Individual and organizational factors that affect implementation of evidence-based practices for children with autism in public schools: a cross-sectional observational study. Children with autism receive most of their intervention services in public schools, but implementation of evidence-based practices (EBPs) for autism varies. Studies suggest that individual (attitudes) and organizational characteristics (implementation leadership and climate) may influence providers' use of EBPs (...) of the three EBPs.Attitudes toward EBPs may affect teachers' decisions to use EBPs; however, implementation leadership and climate did not predict EBP use. Future implementation efforts ought to consider the type of EBP and its fit within the context in terms of the EBP's similarities to and differences from existing practices and programs in the setting. Implementation strategies that target individual attitudes about EBPs may be warranted in public schools.

2019 Implementation Science

13. Sentinel lymph node biopsy in patients affected by breast ductal carcinoma in situ with and without microinvasion: Retrospective observational study. Full Text available with Trip Pro

Sentinel lymph node biopsy in patients affected by breast ductal carcinoma in situ with and without microinvasion: Retrospective observational study. With the introduction of an organized mammographic screening, the incidence of ductal carcinoma in situ (DCIS) has experienced an important increase. Our experience with sentinel lymph node biopsy (SLNB) among patients with DCIS is reviewed.We collected retrospective data on patients operated on their breasts for DCIS (pTis), DCIS

2019 Medicine

14. Morbidity and mortality in a population of patients affected by heart failure and chronic obstructive pulmonary disease: an observational study. Full Text available with Trip Pro

Morbidity and mortality in a population of patients affected by heart failure and chronic obstructive pulmonary disease: an observational study. Chronic obstructive pulmonary disease (COPD) and heart failure (HF) often coexist. Moreover, elderly patients suffering from HF have a higher incidence of COPD, which further complicates their clinical condition. Indacaterol/glycopirronium has shown benefits in the treatment of COPD, with few cardiologic adverse effects. We evaluated the safety

2019 BMC Cardiovascular Disorders

15. Recall of health-related quality of life: how does memory affect the SF-6D in patients with psoriasis or multiple sclerosis? A prospective observational study in Germany. Full Text available with Trip Pro

Recall of health-related quality of life: how does memory affect the SF-6D in patients with psoriasis or multiple sclerosis? A prospective observational study in Germany. This study aimed to quantify recall bias in the measurement of health-related quality of life (HRQoL), that is, the extent to which recollection is impaired and leads to distorted judgements.Prospective observational study.One hundred patients with two paradigmatic chronic diseases (50 with multiple sclerosis and 50

2019 BMJ open

16. Melatonin Affects Postural Control in Community-Dwelling Older Adults While Dual Tasking: A Randomized Observation Study. (Abstract)

Melatonin Affects Postural Control in Community-Dwelling Older Adults While Dual Tasking: A Randomized Observation Study. The effects of a single 3-mg dose of melatonin on the postural control and cognitive performance of community-dwelling older adults were documented. The testing involved stepping down while performing a cognitive task (a Stroop test). Thirty-four older adults were recruited. Immediately before and 1 hr after taking a dose of melatonin, they completed a single-leg standing (...) task after stepping down with and without a simultaneous Stroop test, and a double-leg standing task. The findings indicated a statistically significant increase in sway area under the dual-tasking condition after taking melatonin (p = .04) and the double-leg standing task (p = .018). However, cognitive performance per se was not affected by the melatonin. Melatonin impairs postural control in older adults but not cognitive performance.

2018 Journal of aging and physical activity Controlled trial quality: uncertain

17. Model uncertainties do not affect observed patterns of species richness in the Amazon. Full Text available with Trip Pro

Model uncertainties do not affect observed patterns of species richness in the Amazon. Climate change is arguably a major threat to biodiversity conservation and there are several methods to assess its impacts on species potential distribution. Yet the extent to which different approaches on species distribution modeling affect species richness patterns at biogeographical scale is however unaddressed in literature. In this paper, we verified if the expected responses to climate change (...) in biogeographical scale-patterns of species richness and species vulnerability to climate change-are affected by the inputs used to model and project species distribution.We modeled the distribution of 288 vertebrate species (amphibians, birds and mammals), all endemic to the Amazon basin, using different combinations of the following inputs known to affect the outcome of species distribution models (SDMs): 1) biological data type, 2) modeling methods, 3) greenhouse gas emission scenarios and 4) climate

2017 PLoS ONE

18. Observing dyspnoea in others elicits dyspnoea, negative affect, and brain responses. Full Text available with Trip Pro

Observing dyspnoea in others elicits dyspnoea, negative affect, and brain responses. Dyspnoea is usually caused by diagnosable cardiorespiratory mechanisms. However, frequently dyspnoea relates only weakly or not at all to cardiorespiratory functioning, suggesting that additional neuropsychosocial processes contribute to its experience. We tested whether the mere observation of dyspnoea in others constitutes such a process and would elicit dyspnoea, negative affect and increased brain responses (...) compared to control stimuli. This was paralleled by increased late positive potentials for dyspnoea-related pictures while respiratory variables did not change. Moreover, increased dyspnoea correlated modestly with higher levels of empathy in observers.The present results demonstrate that observing dyspnoea in others elicits mild-to-moderate dyspnoea, negative affect, and increased brain responses in the absence of respiratory changes. This vicarious dyspnoea has clinical relevance, as it might

2018 European Respiratory Journal

19. Risk factors related to mortality of individuals affected by COVID-19 hospitalized in Intensive Care Units: A Systematic Review with meta-analysis of observational studies

Risk factors related to mortality of individuals affected by COVID-19 hospitalized in Intensive Care Units: A Systematic Review with meta-analysis of observational studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) : Inclusion criteria: Exclusion criteria: Inclusion criteria: Exclusion criteria: Inclusion criteria: Exclusion criteria: Example: Screening will be performed in two phases, namely initial screening based on title and abstract, followed by full-text screening of the eligible articles for final inclusion. In each phase, 2 observers will independently assess each article. Discrepancies will be resolved through discussion, or by consulting a third investigator. ">Procedure for study selection Example : Title

2020 PROSPERO

20. Factors Affecting the Effective Management of Acute Stroke: A Prospective Observational Study Full Text available with Trip Pro

Factors Affecting the Effective Management of Acute Stroke: A Prospective Observational Study Stroke, characterized by sudden loss of cerebral function, is among one of the leading cause of death and disability world over. The newer treatment modalities have changed the landscape of stroke treatment but are very much time bound.To characterize pre-hospital and in-hospital factors affecting acute stroke management thus defining lacunae in stroke management.A prospective observational study

2018 Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

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