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Obesity Medication

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61. Medical devices for the treatment of obesity. (PubMed)

Medical devices for the treatment of obesity. Obesity is a major public health concern that leads to numerous metabolic, mechanical and psychological complications. Although lifestyle interventions are the cornerstone of obesity management, subsequent physiological neurohormonal adaptations limit weight loss, strongly favour weight regain and counteract sustained weight loss. A range of effective therapies are therefore needed to manage this chronic relapsing disease. Bariatric surgery delivers (...) substantial, durable weight loss but limited access to care, perceived high risks and costs restrict uptake. Medical devices are uniquely positioned to bridge the gap between more conservative lifestyle intervention and weight-loss pharmacotherapy and more disruptive bariatric surgery. In this Review, we examine the range of gastrointestinal medical devices that are available in clinical practice to treat obesity, as well as those that are in advanced stages of development. We focus on the mechanisms

2017 Nature reviews. Gastroenterology & hepatology

62. Change in use of sleep medications after gastric bypass surgery or intensive lifestyle treatment in adults with obesity. (PubMed)

Change in use of sleep medications after gastric bypass surgery or intensive lifestyle treatment in adults with obesity. To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity.Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss (...) and/or sedatives compared with intensive lifestyle modification.© 2017 The Authors. Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS).

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2017 Obesity

63. Positive predictive value between medical-chart body-mass-index category and obesity versus codes in a claims-data warehouse. (PubMed)

Positive predictive value between medical-chart body-mass-index category and obesity versus codes in a claims-data warehouse. To evaluate the positive predictive value of claims-based V85 codes for identifying individuals with varying degrees of BMI relative to their measured BMI obtained from medical record abstraction.This was a retrospective validation study utilizing administrative claims and medical chart data from 1 January 2009 to 31 August 2015. Randomly selected samples of patients (...) enrolled in a Medicare Advantage Prescription Drug (MAPD) or commercial health plan and with a V85 claim were identified. The claims-based BMI category (underweight, normal weight, overweight, obese class I-III) was determined via corresponding V85 codes and compared to the BMI category derived from chart abstracted height, weight and/or BMI. The positive predictive values (PPVs) of the claims-based BMI categories were calculated with the corresponding 95% confidence intervals (CIs).The overall PPVs

2017 Current medical research and opinion

64. Leveraging psychiatric and medical genetics to understand comorbid depression and obesity. (PubMed)

Leveraging psychiatric and medical genetics to understand comorbid depression and obesity. Precision medicine in psychiatry is on the rise, and depression and obesity - two highly prevalent, comorbid and well-characterised phenotypes - are optimal targets for the approach. Add the bedrock susceptibility gene, FTO, and Riviera et al have identified a constellation of factors that could enhance clinical treatment of both disorders.© The Royal College of Psychiatrists 2017.

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2017 British Journal of Psychiatry

65. Medication use for the treatment of diabetes in obese individuals. (PubMed)

Medication use for the treatment of diabetes in obese individuals. Obesity is a major cause of type 2 diabetes and may complicate type 1 diabetes. Weight loss for obese individuals with diabetes has many health benefits, often leads to improvement in glucose control and sometimes, in type 2 diabetes, near normalisation of abnormal glucose metabolism. Weight loss is difficult to maintain and attempts to lose weight may be undermined by some diabetes treatments such as sulfonylureas (...) , thiazolidinediones and insulin. Whilst lifestyle support should be the primary approach to aid individuals who wish to lose weight, pharmacological approaches can also be considered. These include choosing glucose-lowering drugs or drug combinations that are weight neutral or result in weight loss or prescribing drugs that are specifically approved as anti-obesity medication. Given that some of the newer glucose-lowering medications that cause weight loss, such as glucagon-like peptide-1 receptor agonists (GLP-1

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2017 Diabetologia

66. Food addiction and obesity: unnecessary medicalization of hedonic overeating. (PubMed)

Food addiction and obesity: unnecessary medicalization of hedonic overeating. The concept of addiction is loaded with connotations and is often used for its political as much as its medical utility. The scientific case for 'food addiction' as a clinical phenotype currently rests on its association with generic diagnostic criteria for substance-related disorders being applied to everyday foods and eating-related problems. This has fused the concept of obesity with addiction regardless of whether (...) of a disease. The use of this medical language has implications for the way in which society views overeating and obesity.

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2017 Nature reviews. Endocrinology

67. Non-medically indicated induction in morbidly obese women is not associated with an increased risk of cesarean delivery. (PubMed)

Non-medically indicated induction in morbidly obese women is not associated with an increased risk of cesarean delivery. The prevalence of morbid obesity (body mass index ≥40 kg/m2) in women aged 20-39 years was 7.5% in 2009 through 2010. Morbid obesity is associated with an increased risk of stillbirth compared with normal body mass index, especially >39 weeks' gestation. The data regarding increased risk of cesarean delivery associated with nonmedically indicated induction of labor compared (...) to expectant management in morbidly obese women are limited.We sought to compare the cesarean delivery rate of nonmedically indicated induction of labor with expectant management in morbidly obese women without other comorbidity.This was a retrospective cohort study from the Consortium on Safe Labor of morbidly obese women with singleton, cephalic gestations without previous cesarean, chronic hypertension, or gestational or pregestational diabetes between 37 0/7 and 41 6/7 weeks' gestation. We examined

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2017 American Journal of Obstetrics and Gynecology

68. Translating Comparative Effectiveness Research Into Practice: Effects of Interventions on Lifestyle, Medication Adherence, and Self-care for Type 2 Diabetes, Hypertension, and Obesity Among Black, Hispanic, and Asian Residents of Chicago and Houston, 2010 (PubMed)

Translating Comparative Effectiveness Research Into Practice: Effects of Interventions on Lifestyle, Medication Adherence, and Self-care for Type 2 Diabetes, Hypertension, and Obesity Among Black, Hispanic, and Asian Residents of Chicago and Houston, 2010

2017 Journal of Public Health Management and Practice

69. The Burden of Obesity on Diabetes in the United States: Medical Expenditure Panel Survey, 2008 to 2012. (PubMed)

The Burden of Obesity on Diabetes in the United States: Medical Expenditure Panel Survey, 2008 to 2012. Diabetes is one of the most prevalent and costly chronic diseases in the United States.To analyze the risk of developing diabetes and the annual cost of diabetes for a US general population.Data from the Medical Expenditure Panel Survey, 2008 to 2012, were used to analyze 1) probabilities of developing diabetes and 2) annual total health care expenditures for diabetics. The age-, sex-, race (...) -, and body mass index (BMI)-specific risks of developing diabetes were estimated by fitting an exponential survival function to age at first diabetes diagnosis. Annual health care expenditures were estimated using a generalized linear model with log-link and gamma variance function. Complex sampling designs in the Medical Expenditure Panel Survey were adjusted for. All dollar values are presented in 2012 US dollars.We observed a more than 6 times increase in diabetes risks for class III obese (BMI ≥ 40

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2017 Value in Health

70. Endoscopic Medical Devices for Primary Obesity Treatment in Patients With Diabetes (PubMed)

Endoscopic Medical Devices for Primary Obesity Treatment in Patients With Diabetes IN BRIEF Several new endoscopic bariatric therapies have been approved by the U.S. Food and Drug Administration for the treatment of obesity, with many more devices and procedures undergoing investigational studies. This article describes these devices and procedures and special considerations for their use in patients with diabetes.

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2017 Diabetes spectrum : a publication of the American Diabetes Association

71. Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis (PubMed)

Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis Background: The link between body weight status and spinal diseases has been suggested by a number of cross-sectional and cohort studies with a limited range of patient populations. No population-representative samples have been used to examine the link between obesity and spinal diseases. The present study is based on a nationally representative sample drawn from the Medical Expenditure Panel Survey (...) . Methods: Using the cross-sectional sample of the 2014 Medical Expenditure Panel Study, we built four weighted logistic regression analyses of the associations between body weight status and the following four spinal diseases: low back pain, spondylosis, other cervical disorders and intervertebral disc disorder (IDD). Each respondent's body weight status was used as the key independent variable with three categories: normal/underweight, overweight, and obese. We controlled for marital status, gender

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2017 International journal of environmental research and public health

72. Correlation between obesity and sleep disturbance in Saudi medical students (PubMed)

Correlation between obesity and sleep disturbance in Saudi medical students [Purpose] The aim of the present study was to investigate the association between sleep duration, quality and obesity in the medical students of Saudi population. [Subjects and Methods] This is a cross-sectional study carried out in 408 medical students from King Khalid University Hospitals, Riyadh, Saudi Arabia, based on well-designed questionnaire study and consent form. [Results] The results of this study revealed (...) 39.9% of subjects perform the exercise on regular basis and 61.5% of them reduced their weight, which may be due to diet plan (52.9%) also. Only 68.6% of the subjects were affected with the weight. The maximum number of subjects was lying down after the lunch (88.2%), sitting and reading (80.1%) are prone to develop obesity in future. [Conclusion] Our study confirms sleep disturbance has affected the weight gain and the maximum number of subjects was lying down after the lunch and sitting

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2017 Journal of physical therapy science

73. No evidence for benefit of medication for obesity (PubMed)

No evidence for benefit of medication for obesity 28404699 2017 08 10 2018 12 02 1715-5258 63 4 2017 04 Canadian family physician Medecin de famille canadien Can Fam Physician No evidence for benefit of medication for obesity. 276 Shepherd Robert W RW Victoria, BC. eng Letter Comment Canada Can Fam Physician 0120300 0008-350X IM Can Fam Physician. 2017 Feb;63(2):102-103 28209667 Body Weight Humans Obesity 2017 4 14 6 0 2017 4 14 6 0 2017 8 11 6 0 ppublish 28404699 63/4/276 PMC5389755 N Engl J

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2017 Canadian Family Physician

74. University of Hawai‘i John A. Burns School of Medicine Medical Students' Attitudes Towards Obese Patients (PubMed)

University of Hawai‘i John A. Burns School of Medicine Medical Students' Attitudes Towards Obese Patients Studies have shown that healthcare professionals often demonstrate obesity biases, which in turn reduce the quality of care obese patients receive. The purpose of the current study was to describe third and fourth year University of Hawai'i, John A. Burns School of Medicine medical students' attitudes towards obese patients. Data were collected using previously validated questions from (...) a pilot study assessing how healthcare providers react and recommend medical care to patients with varying characteristics. The responses of 114 medical students were analyzed. Overall, the majority of students' responses reflected the belief that obesity may be a behavioral issue. There were no statistically significant differences between the third and fourth year students' responses. Important areas of future research include assessing students' awareness of the social determinants of health

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2017 Hawai'i Journal of Medicine & Public Health

75. Distinct patterns in the gut microbiota after surgical or medical therapy in obese patients (PubMed)

Distinct patterns in the gut microbiota after surgical or medical therapy in obese patients Bariatric surgery is highly successful in improving health compared to conventional dietary treatments. It has been suggested that the gut microbiota is a relevant factor in weight loss after bariatric surgery. Considering that bariatric procedures cause different rearrangements of the digestive tract, they probably have different effects on the gut microbiota. In this study, we compared the impact (...) of medical treatment, sleeve gastrectomy and Roux-en-Y gastric bypass on the gut microbiota from obese subjects. Anthropometric and clinical parameters were registered before, 6 and 12 months after treatment. Fecal samples were collected and microbiota composition was studied before and six months post treatment using 16S rRNA gene sequencing and qPCR. In comparison to dietary treatment, changes in intestinal microbiota were more pronounced in patients subjected to surgery, observing a bloom

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2017 PeerJ

76. The prevalence of obesity documentation in Primary Care Electronic Medical Records: Are we acknowledging the problem? (PubMed)

The prevalence of obesity documentation in Primary Care Electronic Medical Records: Are we acknowledging the problem? Although obesity is a growing problem, primary care physicians often inadequately address it. The objective of this study is to examine the prevalence of obesity documentation in the patient's problem list for patients with eligible body mass indexes (BMI) as contained in the patients' electronic medical record (EMR). Additionally, we examined the prevalence of selected chronic (...) conditions across BMI levels.This study is a retrospective study using EMR data for adult patients visiting an outpatient clinic between June 2012 and June 2015. International Classification of Diseases, Ninth Revision, (ICD-9) codes were used to identify obesity documentation in the EMR problem list. Univariate and multivariate logistic regression analyses were used.Out of 10,540, a total of 3,868 patients were included in the study. 2,003 (52%) patients met the criteria for obesity (BMI ≥ 30.0

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2017 Applied clinical informatics

77. Should family physicians prescribe medication for obesity?: YES (PubMed)

Should family physicians prescribe medication for obesity?: YES 28209667 2017 03 30 2018 12 02 1715-5258 63 2 2017 Feb Canadian family physician Medecin de famille canadien Can Fam Physician Should family physicians prescribe medication for obesity? YES. 102-103 Bourns Laura L Family physician completing her residency in Public Health and Preventive Medicine at the University of Ottawa in Ontario. lbour035@uottawa.ca. Shiau Judy J Medical Director of the LEAF Weight Management Clinic (...) and Assistant Professor and Bariatric Medicine Fellowship Program Director at the University of Ottawa. eng Journal Article Canada Can Fam Physician 0120300 0008-350X 0 Anti-Obesity Agents 0 Lactones 839I73S42A Liraglutide 95M8R751W8 Orlistat IM Can Fam Physician. 2017 Feb;63(2):e83 28209694 Can Fam Physician. 2017 Apr;63(4):276 28404699 Can Fam Physician. 2017 Apr;63(4):276-277 28404700 Anti-Obesity Agents adverse effects therapeutic use Body Mass Index Family Practice methods Humans Lactones therapeutic

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2017 Canadian Family Physician

78. Should family physicians prescribe medication for obesity?: NO (PubMed)

Should family physicians prescribe medication for obesity?: NO 28209668 2017 03 30 2018 12 02 1715-5258 63 2 2017 Feb Canadian family physician Medecin de famille canadien Can Fam Physician Should family physicians prescribe medication for obesity? NO. 103-105 Shaw Elizabeth E Family physician and Professor of Family Medicine at McMaster University in Hamilton, Ont. shawea@mcmaster.ca. eng Journal Article Canada Can Fam Physician 0120300 0008-350X 0 Anti-Obesity Agents 0 Lactones 839I73S42A (...) Liraglutide 9100L32L2N Metformin 95M8R751W8 Orlistat IM Can Fam Physician. 2017 Feb;63(2):e82 28209693 Can Fam Physician. 2017 Feb;63(2):e83 28209694 Can Fam Physician. 2017 Apr;63(4):276-277 28404700 Anti-Obesity Agents adverse effects therapeutic use Body Mass Index Family Practice methods Humans Lactones therapeutic use Liraglutide therapeutic use Male Metformin therapeutic use Obesity drug therapy therapy Orlistat Practice Guidelines as Topic Practice Patterns, Physicians' 2017 2 18 6 0 2017 2 18 6 0

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2017 Canadian Family Physician

79. Rebuttal: Should family physicians prescribe medication for obesity?: YES (PubMed)

Rebuttal: Should family physicians prescribe medication for obesity?: YES 28209693 2017 04 05 2018 12 02 1715-5258 63 2 2017 02 Canadian family physician Medecin de famille canadien Can Fam Physician Rebuttal: Should family physicians prescribe medication for obesity? YES. e82 Bourns Laura L Family physician completing her residency in Public Health and Preventive Medicine at the University of Ottawa in Ontario. lbour035@uottawa.ca. Shiau Judy J Medical Director of the LEAF Weight Management (...) Clinic and Assistant Professor and Bariatric Medicine Fellowship Program Director at the University of Ottawa. eng Journal Article Comment Canada Can Fam Physician 0120300 0008-350X IM Can Fam Physician. 2017 Feb;63(2):103-105 28209668 Family Practice Humans Obesity drug therapy Physicians, Family Practice Patterns, Physicians' Prescriptions 2017 2 18 6 0 2017 2 18 6 0 2017 4 6 6 0 ppublish 28209693 63/2/e82 PMC5395399 Diabetes Care. 2004 Jan;27(1):155-61 14693982 Am Psychol. 2007 Apr;62(3):220-33

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2017 Canadian Family Physician

80. Rebuttal: Should family physicians prescribe medication for obesity?: NO (PubMed)

Rebuttal: Should family physicians prescribe medication for obesity?: NO 28209694 2017 04 05 2018 12 02 1715-5258 63 2 2017 02 Canadian family physician Medecin de famille canadien Can Fam Physician Rebuttal: Should family physicians prescribe medication for obesity? NO. e83 Shaw Elizabeth E Family physician and Professor of Family Medicine at McMaster University in Hamilton, Ont. shawea@mcmaster.ca. eng Journal Article Comment Canada Can Fam Physician 0120300 0008-350X IM Can Fam Physician (...) . 2017 Feb;63(2):102-103 28209667 Can Fam Physician. 2017 Feb;63(2):103-105 28209668 Humans Obesity drug therapy Physicians Physicians, Family Practice Patterns, Physicians' Prescriptions 2017 2 18 6 0 2017 2 18 6 0 2017 4 6 6 0 ppublish 28209694 63/2/e83 PMC5395400 Arch Intern Med. 2011 Apr 11;171(7):703-4 21482850 CMAJ. 2015 Feb 17;187(3):184-95 25623643 N Engl J Med. 2015 Oct 29;373(18):1779 26510029 BMJ. 2008 Dec 11;337:a2509 19074218 J Clin Endocrinol Metab. 2015 Feb;100(2):342-62 25590212 Can

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2017 Canadian Family Physician

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