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21. A Medically Supervised Pregnancy Exercise Intervention in Obese Women: A Randomized Controlled Trial

A Medically Supervised Pregnancy Exercise Intervention in Obese Women: A Randomized Controlled Trial To evaluate whether an intensive, medically supervised exercise intervention improved maternal glycemia and gestational weight gain in obese pregnant women when compared with routine prenatal care.This randomized controlled trial compared a medically supervised exercise intervention with routine prenatal care. The primary outcome was a reduction in mean maternal fasting plasma glucose (...) of gestation, excessive gestational weight gain greater than 9.1 kg was lower in the exercise group, 23.5% compared with 45.2% in the control group (P<.05).An intensive, medically supervised exercise intervention for obese women from early pregnancy did not improve maternal glycemia. Pregnant women who are obese, however, should be advised to exercise because it attenuates excessive gestational weight gain.International Standard Randomised Controlled Trials (ISRCTN) registry, ISRCTN 31045925.

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2017 EvidenceUpdates

22. A Randomized, Controlled Multisite Study of Behavioral Interventions for Veterans with Mental Illness and Antipsychotic Medication-Associated Obesity

A Randomized, Controlled Multisite Study of Behavioral Interventions for Veterans with Mental Illness and Antipsychotic Medication-Associated Obesity Weight gain and other metabolic sequelae of antipsychotic medications can lead to medication non-adherence, reduced quality of life, increased costs, and premature mortality. Of the approaches to address this, behavioral interventions are less invasive, cost less, and can result in sustained long-term benefits.We investigated behavioral weight (...) management interventions for veterans with mental illness across four medical centers within the Veterans Affairs (VA) Healthcare System.We conducted a 12-month, multi-site extension of our previous randomized, controlled study, comparing treatment and control groups.Veterans (and some non-veteran women) diagnosed with mental illness, overweight (defined as having a BMI over 25), and required ongoing antipsychotic therapy.One group received "Lifestyle Balance" (LB; modified from the Diabetes Prevention

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2017 EvidenceUpdates

23. Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management (PubMed)

Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management Bariatric surgery is today the most effective long-term therapy for the management of patients with severe obesity, and its use is recommended by the relevant guidelines of the management of obesity in adults. Bariatric surgery is in general safe and effective, but it can cause new clinical problems and is associated with specific (...) diagnostic, preventive and therapeutic needs. For clinicians, the acquisition of special knowledge and skills is required in order to deliver appropriate and effective care to the post-bariatric patient. In the present recommendations, the basic notions needed to provide first-level adequate medical care to post-bariatric patients are summarised. Basic information about nutrition, management of co-morbidities, pregnancy, psychological issues as well as weight regain prevention and management is derived

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2017 Obesity facts

24. The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis

The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could (...) of competing interests We believe that readers should be aware of any competing interests (conflicts of interest). The International Committee of Medical Journal Editors (ICMJE) define competing interests as including: financial relationships with industry (for example through employment, consultancies, stock, ownership, honoraria, and expert testimony), either directly or through immediate family; personal relationships; academic competition; and intellectual passion. If yes, please provide details below

2015 NIHR HTA programme

25. A review of the evidence base for modelling the costs of overweight, obesity and diet-related illness for Scotland, and critical appraisal of the cost-effectiveness evidence base for population wide interventions to reduce overweight, obesity and diet-rel

). Of the remaining three, one paper only considered medications costs and cost savings, one paper was a letter/commentary of conference proceedings, and one paper considered BMI 21-25 as well as overweight and obesity. This produced a final total of 14 relevant studies. 16 Figure 2 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta- Analyses) flow chart of cost of illness studies Records identified through database searching (n = 428) Screening Included Eligibility Identification Additional (...) is higher in Scotland than in England (65% v 63% and 29% v 27% respectively). Further, obesity prevalence rates have risen in both Scotland and England since 2006/7. Finally, medical and surgical treatment options for obesity and conditions related to obesity (e.g. diabetes, hypertension, cardiovascular disease) have increased over the last 10 years. Castle et al (2015) also noted the potential magnitude of the costs of lost productivity due to morbidity and mortality, and with these added to health

2017 Health Economics Research Unit

26. Systematic review and meta-analysis: Bariatric surgery produces greater weight loss and improvements in medical conditions than non-surgical treatment of obesity

Systematic review and meta-analysis: Bariatric surgery produces greater weight loss and improvements in medical conditions than non-surgical treatment of obesity Bariatric surgery produces greater weight loss and improvements in medical conditions than non-surgical treatment of obesity | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we (...) -surgical treatment of obesity Article Text Therapeutics Systematic review and meta-analysis Bariatric surgery produces greater weight loss and improvements in medical conditions than non-surgical treatment of obesity Kristoffel Dumon , Goda Savulionyte Statistics from Altmetric.com Commentary on: Gloy VL , Briel M , Bhatt DL , et al . Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials . Request Permissions If you wish

2014 Evidence-Based Medicine (Requires free registration)

27. Antibiotic and acid-suppression medications during early childhood are associated with obesity. (PubMed)

Antibiotic and acid-suppression medications during early childhood are associated with obesity. Gut microbiota alterations are associated with obesity. Early exposure to medications, including acid suppressants and antibiotics, can alter gut biota and may increase the likelihood of developing obesity. We investigated the association of antibiotic, histamine-2 receptor antagonist (H2RA) and proton pump inhibitor (PPI) prescriptions during early childhood with a diagnosis of obesity.We performed (...) a cohort study of US Department of Defense TRICARE beneficiaries born from October 2006 to September 2013. Exposures were defined as having any dispensed prescription for antibiotic, H2RA or PPI medications in the first 2 years of life. A single event analysis of obesity was performed using Cox proportional hazards regression.333 353 children met inclusion criteria, with 241 502 (72.4%) children prescribed an antibiotic, 39 488 (11.8%) an H2RA and 11 089 (3.3%) a PPI. Antibiotic prescriptions were

2018 Gut

28. Medical Versus Surgical ICU Obese Patient Outcome: A Propensity-Matched Analysis to Resolve Clinical Trial Controversies. (PubMed)

Medical Versus Surgical ICU Obese Patient Outcome: A Propensity-Matched Analysis to Resolve Clinical Trial Controversies. To determine the short- and long-term mortality of obese ICU patients following medical as opposed to surgical admission and the relation between obesity and mortality.Retrospective analysis of prospectively collected data, using a propensity score-matched analysis of patients with medical or surgical admission.One French mixed medical-surgical ICU.Critically ill obese (...) patients (body mass index ≥ 30 kg/m) and nonobese patients admitted during a 14-year period.None.Seven-hundred ninety-one obese patients and 4,644 nonobese patients were included, 338 (43%) and 2,367 (51%) medical and 453 (57%) and 2,277 (49%) surgical obese and nonobese patients, respectively. Mortality was significantly higher in medical than in surgical obese patients in ICU (25% vs 12%; p < 0.001) and up to 365 days (36% vs 18%; p < 0.001) post ICU admission. One-to-one propensity score matching

2018 Critical Care Medicine

29. 7. Obesity Management for the Treatment of Type 2 Diabetes: <i>Standards of Medical Care in Diabetes-2018</i>. (PubMed)

7. Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes-2018. The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible

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2018 Diabetes Care

30. Early Childhood Obesity Risk Factors: Socioeconomic Adversity, Family Dysfunction, Offspring Distress, and Junk Food Self-Medication (PubMed)

Early Childhood Obesity Risk Factors: Socioeconomic Adversity, Family Dysfunction, Offspring Distress, and Junk Food Self-Medication To explore the sequence and interaction of infancy and early childhood risk factors, particularly relating to disturbances in the social environment, and how the consequences of such exposures can promote weight gain and obesity.This review will argue that socioeconomic adversity is a key upstream catalyst that sets the stage for critical midstream risk factors (...) such as family strain and dysfunction, offspring insecurity, stress, emotional turmoil, low self-esteem, and poor mental health. These midstream risk factors, particularly stress and emotional turmoil, create a more or less perfect foil for calorie-dense junk food self-medication and subtle addiction, to alleviate uncomfortable psychological and emotional states. Disturbances in the social environment during infancy and early childhood appear to play a critical role in weight gain and obesity, through

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2018 Current obesity reports

31. Beyond lifestyle interventions: exploring the potential of anti‐obesity medications in the UK (PubMed)

Beyond lifestyle interventions: exploring the potential of anti‐obesity medications in the UK In the UK, over one-quarter of the adult population have obesity (body mass index ≥30 kg m-2 ). This has major implications for patients' health and the National Health Service. Despite published studies showing that significant weight loss can be achieved and maintained in primary care, and guidance from the National Institute for Health and Care Excellence, weight management services (...) are inconsistently implemented. This may be due primarily to workload and financial constraints. There is also a lack of belief that specialist weight management services and anti-obesity medications (AOMs) are a viable alternative to bariatric surgery for long-term maintenance of weight loss. This article discusses the challenges facing obesity management and explores the reasons for the lack of investment in AOMs in the UK to date. The aim of this article is to identify whether the newer AOMs

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2018 Clinical Obesity

32. Erratum: Endoscopic Medical Devices for Primary Obesity Treatment in Patients With Diabetes. Diabetes Spectrum 2017;30;258–264 (DOI:10.2337/ds017-0046) (PubMed)

Erratum: Endoscopic Medical Devices for Primary Obesity Treatment in Patients With Diabetes. Diabetes Spectrum 2017;30;258–264 (DOI:10.2337/ds017-0046) [This corrects the article on p. 258 in vol. 30, PMID: 29151716.].

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2018 Diabetes spectrum : a publication of the American Diabetes Association

33. Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment

Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Establishment of a Database of Patients Suffering From Obesity With a Medical Treatment (Elodie Cohort) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03755323 Recruitment Status : Recruiting First

2018 Clinical Trials

34. The Association between Antihypertensive Medication Use and Blood Pressure Is Influenced by Obesity (PubMed)

The Association between Antihypertensive Medication Use and Blood Pressure Is Influenced by Obesity One in three US adults is living with obesity or hypertension, and more than 75% of hypertensive individuals are using antihypertensive medications. Therefore, it is important to examine blood pressure (BP) differences in populations that are using these medications with differing obesity status.We examined whether BP attained when using various antihypertensive medications varies amongst (...) medications (NoBPMed) (P < 0.05), whereby in women, the differences in systolic BP between angiotensin-converting-enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) users and NoBPMed were greater in those with obesity (ACE inhibitors: -14 ± 1 mmHg; ARB: -16 ± 1 mmHg) compared to normal weight individuals (ACE inhibitors: -9 ± 1 mmHg; ARB: -11 ± 1 mmHg) (P < 0.05). Diastolic BP differences between women ARB users and NoBPMed were also greatest in obesity (-5 ± 1 mmHg) (P < 0.05) whilst there were

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2018 Journal of obesity

35. Who pays for the medical costs of obesity? New evidence from the employer mandate. (PubMed)

Who pays for the medical costs of obesity? New evidence from the employer mandate. Theory suggests that the medical costs of obesity should be passed on to obese workers, in the form of lower wages, whenever health coverage is a part of employee compensation. In contrast to existing work on this topic, this paper illustrates that the medical expenditures caused by obesity among working adults are relatively small and that wage offsets should therefore be difficult to detect. The paper supports (...) this claim by exploiting the variation provided by the Affordable Care Act's employer mandate. Findings suggest that obese workers tend to bear the approximate cost of their medical expenditures via lower wages. However, the observed effects are often insignificantly different from zero.© 2018 John Wiley & Sons, Ltd.

2018 Health economics

36. New Evidence on the Effect of Medical Insurance on the Obesity Risk of Rural Residents: Findings from the China Health and Nutrition Survey (CHNS, 2004–2011) (PubMed)

New Evidence on the Effect of Medical Insurance on the Obesity Risk of Rural Residents: Findings from the China Health and Nutrition Survey (CHNS, 2004–2011) The obesity rate in China has risen significantly in the past few decades. While a number of causes for the rise in obesity have been explored, little attention has been paid to the role of health insurance per se. This study aims to investigate the impact of health insurance on the risk of obesity in rural China using longitudinal data (...) from the China Health and Nutrition Survey (CHNS). We employed pooled ordinary least squares (OLS), probit estimation, and pooled two-stage least squares (2SLS) for an instrumental variable (IV). The IV model revealed that New rural cooperative medical insurance (NRCMS) participation had a significant positive impact on people's tendency towards unhealthy lifestyles, for instances, high-fat food (8.01% for female and 7.35% for male), cigarette smoking (25% for male), heavy drinking (25% for female

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2018 International journal of environmental research and public health

37. Safety and tolerability of new-generation anti-obesity medications: a narrative review (PubMed)

Safety and tolerability of new-generation anti-obesity medications: a narrative review The prevalence of obesity and associated comorbidities is rising. Despite their weight-loss efficacy, new generation anti-obesity medications are only prescribed to a minority of adults with obesity, possibly, which in part may be due to safety concerns. This review presents detailed safety profiles for orlistat, phentermine/topiramate, lorcaserin, naltrexone/bupropion and liraglutide 3.0 mg, and discusses (...) the associated risk-benefit profiles. Two anti-obesity medications presented safety issues that warranted further discussion; phentermine/topiramate (fetal toxicity) and liraglutide 3.0 mg (risk of gallstone disease and mild, acute pancreatitis), whereas the adverse events associated with orlistat, lorcaserin, and naltrexone/bupropion were mostly transient tolerability issues. The difficulties surrounding the objective determination of risk-benefit for anti-obesity medications is discussed. The need for more

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2018 Postgraduate medicine

38. Ileal interposition coupled with duodenal diverted sleeve gastrectomy versus standard medical treatment in type 2 diabetes mellitus obese patients: long-term results of a case-control study. (PubMed)

Ileal interposition coupled with duodenal diverted sleeve gastrectomy versus standard medical treatment in type 2 diabetes mellitus obese patients: long-term results of a case-control study. Randomized controlled trials have demonstrated that bariatric surgery is effective in obtaining remission of type 2 diabetes mellitus (T2DM) in obese patients, yet no data exist in the literature from prospective studies with ileal interposition with duodenal diversion sleeve gastrectomy (II-DD-SG). The aim (...) of this case-control study is to investigate if II-DD-SG is superior to medical treatment in T2DM obese patients.Thirty obese patients (BMI > 30) affected by T2DM were recruited for surgery (II-DD-SG) between 2008 and 2011 and were matched with an equal control group which received standard medical treatment. Anthropometric measures, glucose metabolism, cardiovascular risk factors were determined baseline and during follow-up. The primary end point was T2DM remission; reduction of body weight, BMI

2018 Surgical endoscopy

39. Laparoscopic Conversion of a Vertical Banded Gastroplasty to a Sleeve Gastrectomy in a Morbidly Obese Patient with a Complicated Medical History. (PubMed)

Laparoscopic Conversion of a Vertical Banded Gastroplasty to a Sleeve Gastrectomy in a Morbidly Obese Patient with a Complicated Medical History. We present our technique for performing a laparoscopic conversion of vertical banded gastroplasty (VBG) to sleeve gastrectomy (SG) in a morbidly obese patient.A 58-year-old female with history of hypertension, diabetes, and morbid obesity (BMI 41). She had initially undergone an open VBG (BMI 58) and cholecystectomy (2002) and subsequently underwent

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2018 Obesity Surgery

40. Obesity: Are shared medical appointments part of the answer? (PubMed)

Obesity: Are shared medical appointments part of the answer? Shared medical appointments, in which a multidisciplinary team of healthcare providers meets with multiple patients in a group setting, may be an option for treating patients with obesity. To be effective, shared medical appointments need to address patients' nutrition, physical activity, appetite suppression, stress management, and sleep.Copyright © 2018 Cleveland Clinic.

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2018 Cleveland Clinic Journal of Medicine

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