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181. Compliance with current VTE prophylaxis guidelines and risk factors linked to complications of VTE prophylaxis in medical inpatients: a prospective cohort study in a Spanish internal medicine department. Full Text available with Trip Pro

Compliance with current VTE prophylaxis guidelines and risk factors linked to complications of VTE prophylaxis in medical inpatients: a prospective cohort study in a Spanish internal medicine department. To evaluate the degree of compliance with the current guidelines regarding venous thromboembolism (VTE) prophylaxis in medical patients during admission and to identify risk factors linked to complications of VTE prophylaxis.Prospective cohort study.The Internal Medicine Department (...) antiplatelet treatment (OR 2.7; 95% CI 1.1 to 6.5, p=0.03) and enoxaparin use (OR 3.5; 95% CI 1.1 to 10.9, p=0.029), and the presence of minor haematomas was associated with PADOVA index <4 points (OR 3.1; 95% CI 1.5 to 6.4, p=0.003) and diabetes mellitus (OR 2; 95% CI 1.1 to 3.7, p=0.031).Complications during VTE prophylaxis in elderly hospitalised medical patients are frequent even with correct application of current guidelines. The main factors linked to haematomas were obesity and concomitant

2018 BMJ open

182. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. Full Text available with Trip Pro

Bariatric surgery versus intensive medical therapy in obese patients with diabetes. Observational studies have shown improvement in patients with type 2 diabetes mellitus after bariatric surgery.In this randomized, nonblinded, single-center trial, we evaluated the efficacy of intensive medical therapy alone versus medical therapy plus Roux-en-Y gastric bypass or sleeve gastrectomy in 150 obese patients with uncontrolled type 2 diabetes. The mean (±SD) age of the patients was 49±8 years, and 66 (...) ). Glycemic control improved in all three groups, with a mean glycated hemoglobin level of 7.5±1.8% in the medical-therapy group, 6.4±0.9% in the gastric-bypass group (P<0.001), and 6.6±1.0% in the sleeve-gastrectomy group (P=0.003). Weight loss was greater in the gastric-bypass group and sleeve-gastrectomy group (-29.4±9.0 kg and -25.1±8.5 kg, respectively) than in the medical-therapy group (-5.4±8.0 kg) (P<0.001 for both comparisons). The use of drugs to lower glucose, lipid, and blood-pressure levels

2012 NEJM Controlled trial quality: uncertain

183. Surgery or Medical Therapy for Obese Patients with Type 2 Diabetes? Full Text available with Trip Pro

Surgery or Medical Therapy for Obese Patients with Type 2 Diabetes? 22449318 2012 04 27 2018 12 01 1533-4406 366 17 2012 Apr 26 The New England journal of medicine N. Engl. J. Med. Surgery or medical therapy for obese patients with type 2 diabetes? 1635-6 10.1056/NEJMe1202443 Zimmet Paul P Alberti K George M M KG eng Editorial Comment 2012 03 26 United States N Engl J Med 0255562 0028-4793 0 Hypoglycemic Agents AIM IM N Engl J Med. 2012 Apr 26;366(17):1567-76 22449319 N Engl J Med. 2012 Apr (...) 26;366(17):1577-85 22449317 Biliopancreatic Diversion Diabetes Mellitus, Type 2 drug therapy surgery Female Gastrectomy Gastric Bypass Humans Hypoglycemic Agents therapeutic use Male Obesity surgery Obesity, Morbid surgery 2012 3 28 6 0 2012 3 28 6 0 2012 4 28 6 0 ppublish 22449318 10.1056/NEJMe1202443

2012 NEJM

184. Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Preclinical Cancer Drug Cardiotoxicity Testing: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

, as well as structural abnormalities, making it possible to deliver novel drugs free from cardiac liabilities and guide personalized therapy. This article briefly reviews the challenges of cardio-oncology, the strengths and limitations of using human induced pluripotent stem cell–derived cardiomyocytes to represent clinical findings in the nonclinical research space, and future directions for their further use. In the United States and Europe, cancer is the second leading cause of death and morbidity (...) targeted therapies, and mediastinal irradiation, resulting in cardiomyocyte and vascular damage. Cancer survivors may have markedly reduced life expectancy with evidence of coronary artery disease in their 30s, especially if additional risk factors such as hypertension, diabetes mellitus, obesity, and dyslipidemia are also present. , In particular, congestive heart failure as a result of cancer therapy has been linked to a 3.5-fold increased mortality risk compared with idiopathic cardiomyopathy

2019 American Heart Association

185. Immediate postpartum long-acting reversible contraception for women at high risk for medical complications Full Text available with Trip Pro

levonorgestrel 0.1 5 yrs Kyleena 19.5 mg of levonorgestrel 0.1 5 yrs Skyla 13.5 mg of levonorgestrel 0.1 3 yrs Subdermal implant Nexplanon Etonogestrel 68 mg 0.2 3 yrs FDA, Food and Drug Administration. a Percentage of women experiencing an unintended pregnancy within the ?rst year of typical use; b There is evidence for extended use for some of these devices. 18 Society for Maternal-Fetal Medicine: Postpartum LARC for medical complications. Am J Obstet Gynecol 2019. smfm.org SMFM Consult Series MAY 2019 (...) Immediate postpartum long-acting reversible contraception for women at high risk for medical complications SocietyforMaternal-FetalMedicine(SMFM) ConsultSeries#48:Immediatepostpartum long-actingreversiblecontraceptionforwomen athighriskformedicalcomplications Society for Maternal-Fetal Medicine (SMFM); Laura K. Vricella, MD; Lori M. Gawron, MD, MPH; Judette M. Louis, MD, MPH The Society of Family Planning (SFP) endorses this document. The American College of Obstetricians and Gynecologists

2019 Society for Maternal-Fetal Medicine

186. Use of Hormonal Contraception in Women With Coexisting Medical Conditions

immunodeficiency virus (HIV) ; the use of emergency contraception in women with medical coexisting medical conditions, including obesity, ; and the effect of depot medroxyprogesterone acetate (DMPA) on bone health are addressed in other documents from the American College of Obstetricians and Gynecologists. Log in to read more This content is only available to members and subscribers. Nonmembers: Subscribe now to access exclusive ACOG Clinical content, including: ACOG Clinical is designed for easy (...) Use of Hormonal Contraception in Women With Coexisting Medical Conditions Use of Hormonal Contraception in Women With Coexisting Medical Conditions | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance Use of Hormonal Contraception in Women With Coexisting Medical Conditions Practice Bulletin Number 206 February 2019 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions

2019 American College of Obstetricians and Gynecologists

187. Obesity Is Associated with an Increase in Pharmaceutical Expenses among University Employees Full Text available with Trip Pro

Obesity Is Associated with an Increase in Pharmaceutical Expenses among University Employees To examine costs associated with obesity in an employee population and factors associated with increased costs.We used data from the Physical Activity and Life Style (PALS) study, a randomized prospective design evaluating three interventions to increase physical activity among physically inactive nonfaculty university employees (n = 454). The primary exposure variable, obesity (measured by body mass (...) index), was obtained from the in-person baseline survey. Covariates were obtained from the baseline survey and included demographic characteristics and health status. Data from the baseline survey was linked with administrative data to determine pharmaceutical, inpatient, outpatient, and total health care costs for three years. Average monthly expenditures for obese and nonobese individuals were compared using t-tests and a two-part multivariate regression model adjusted for demographic

2015 Journal of obesity Controlled trial quality: uncertain

188. Does whole body vibration therapy assist in reducing fat mass or treating obesity in the overweight and obese general population? A systematic review and meta-analysis

Does whole body vibration therapy assist in reducing fat mass or treating obesity in the overweight and obese general population? A systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) , editorial) 2. Not an in vivo animal study 3. No metastases/ only primary tumor 4. No control group 5. Combination therapy or contamination 6. Not about analgesics used in the clinic Full text-screening: As above, with the addition of: 7. No relevant outcome measure reported ">Prioritise the exclusion criteria Example: Two reviewers will independently extract data from each article. We first try to extract numerical data from tables, text or figures. If these are not reported, we will extract data from

2019 PROSPERO

189. Physical health and drug safety in individuals with schizophrenia Full Text available with Trip Pro

Physical health and drug safety in individuals with schizophrenia While antipsychotic medications are the mainstay of therapy for individuals with schizophrenia and psychotic disorders, their use is associated with adverse effects on physical health that require the attention and care of prescribers.We used the ADAPTE process to adapt existing guideline recommendations from the National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN (...) interventions are recommended to mitigate antipsychotic-induced weight gain. Prescribers should follow Canadian guidelines on the treatment of obesity, dyslipidemia, and diabetes. Recommendations on antipsychotic drug choice are made for users particularly concerned about extrapyramidal symptoms.Careful monitoring and attention by prescribers may mitigate adverse effects associated with antipsychotic medications.

2017 CPG Infobase

190. [Effect of Acupuncture Therapy on Body Compositions in Patients with Obesity]. (Abstract)

[Effect of Acupuncture Therapy on Body Compositions in Patients with Obesity]. To observe the clinical effectiveness of acupuncture intervention in weight reduction by modulating body compositions in obesity patients.A total of 71 obesity patients during weight-loss procedure were allocated to acupuncture+nutrition-consultation group (n=40) and simple nutrition-consultation group (n=31). The patients of the acupuncture +nutrition-consultation group were treated by acupuncture stimulation (...) of acupuncture+nutrition-consultation group was markedly superior to that of the simple nutrition-consultation group in increasing the improved degrees of body weight, BMI, fat mass and fat percentage (P<0.01).Acupuncture plus nutrition consultation is effective in reducing body mass, fat mass and percentage of body fat in obesity patients.

2018 Zhen ci yan jiu = Acupuncture research Controlled trial quality: uncertain

191. A randomised controlled trial of manualized cognitive remediation therapy in adult obesity. Full Text available with Trip Pro

A randomised controlled trial of manualized cognitive remediation therapy in adult obesity. Research has indicated that individuals with obesity have neurocognitive deficits, especially in cognitive flexibility that may in turn impact on their weight loss and maintenance. Consequently, we examined the efficacy of a manualised face-to-face cognitive remediation therapy for obesity (CRT-O) within a randomised controlled trial, in terms of improving cognitive flexibility, reducing binge eating (...) behaviour, improving quality of life and helping with weight loss.80 adults with obesity (body mass index >30 kg/m2), 70% binge eaters, received three weekly sessions of group Behavioural Weight Loss (BWL) and then were randomised to 8 sessions of individual CRT-O or to a no-treatment control group.Mixed-effects model analyses revealed that the CRT-O group had a significant improvement in their cognitive flexibility at post-treatment and 3-month follow-up compared to the control group (Cohen's d = 0.96

2018 Appetite Controlled trial quality: uncertain

192. The impact of testosterone replacement therapy on glycemic control, vascular function, and components of the metabolic syndrome in obese hypogonadal men with type 2 diabetes. (Abstract)

The impact of testosterone replacement therapy on glycemic control, vascular function, and components of the metabolic syndrome in obese hypogonadal men with type 2 diabetes. This study set out to assess effects of testosterone replacement therapy (TRT) on parameters of metabolic syndrome and vascular function in obese hypogonadal males with type 2 diabetes mellitus (DM2).Fifty-five obese hypogonadal diabetic males on oral hypoglycemic treatment were enrolled into this one-year, double-blind

2018 The aging male : the official journal of the International Society for the Study of the Aging Male Controlled trial quality: uncertain

193. High-Flow Nasal Cannula Therapy Versus Intermittent Noninvasive Ventilation in Obese Subjects After Cardiothoracic Surgery. Full Text available with Trip Pro

High-Flow Nasal Cannula Therapy Versus Intermittent Noninvasive Ventilation in Obese Subjects After Cardiothoracic Surgery. Obese patients are considered at risk of respiratory failure after cardiothoracic surgery. High-flow nasal cannula has demonstrated its non-inferiority after cardiothoracic surgery compared to noninvasive ventilation (NIV), which is the recommended treatment in obese patients. We hypothesized that NIV was superior to high-flow nasal cannula for preventing or resolving (...) acute respiratory failure after cardiothoracic surgery in this population.We performed a post hoc analysis of a randomized, controlled trial. Obese subjects were randomly assigned to receive NIV for at least 4 h/d (inspiratory pressure, 8 cm H2O; expiratory pressure, 4 cm H2O; FIO2 , 0.5) or high-flow nasal cannula delivered continuously (flow, 50 L/min, FIO2 0.5).Treatment failure (defined as re-intubation, switch to the other treatment, or premature discontinuation) occurred in 21 of 136 (15.4

2018 Respiratory care Controlled trial quality: uncertain

194. [Evaluate the Efficacy of Electroacupuncture Therapy on Abdominal Fat in Obese Women by Using Magnetic Resonance Imaging]. (Abstract)

[Evaluate the Efficacy of Electroacupuncture Therapy on Abdominal Fat in Obese Women by Using Magnetic Resonance Imaging]. To evaluate the efficacy of electroacupuncture (EA) therapy on abdominal fat in obese women by using magnetic resonance imaging(MRI).Thirty abdominal obesity women patients were randomly divided into control group (n=15) and EA group (n=15). The obesity patients of the control group did not receive any treatment for weight reduction, and those of the EA group were treated (...) tissue thickness at the level of the superior edge of the pubic symphysis and the total abdominal fat volume between L4 and S3 in the control group (P>0.05).EA intervention can effectively reduce abdominal fat in obese women based on the evaluation of MRI.

2018 Zhen ci yan jiu = Acupuncture research Controlled trial quality: uncertain

195. Changes in Body Adiposity, Dietary Intake, Physical Activity and Quality of Life of Obese Individuals Submitted to Intragastric Balloon Therapy for 6 Months. (Abstract)

Changes in Body Adiposity, Dietary Intake, Physical Activity and Quality of Life of Obese Individuals Submitted to Intragastric Balloon Therapy for 6 Months. Obesity is an important risk factor for several chronic diseases and also is associated with worse quality of life. Intragastric balloon (IGB) is an effective method for weight loss. Although changes in lifestyle are critical to weight loss during and after IGB therapy, only a few studies evaluated dietary intake and none evaluated changes (...) in physical activity with a validated questionnaire during the treatment. The aim of this study was to evaluate changes in total and central body adiposity, dietary intake, physical activity, and quality of life of patients with obesity submitted to IGB treatment for 6 months.Prospective observational study involving 42 patients with obesity using IGB for 6 months. The patients were evaluated, on the day of insertion and withdrawal or adjustment of IGB for total and central body adiposity (anthropometry

2018 Obesity Surgery

196. Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy

Product: No Product Manufactured in and Exported from the U.S.: No Keywords provided by Johns Hopkins University: Gastric Mucosal Devitalization Obesity Endoscopic Bariatric Therapies Bariatric surgery Additional relevant MeSH terms: Layout table for MeSH terms Obesity Obesity, Morbid Overnutrition Nutrition Disorders Overweight Body Weight Signs and Symptoms (...) Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

197. PAP Therapy in Patients With Obesity Hypoventilation Syndrome

PAP Therapy in Patients With Obesity Hypoventilation Syndrome PAP Therapy in Patients With Obesity Hypoventilation Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. PAP Therapy in Patients (...) Study Details Study Description Go to Brief Summary: The role of different levels of compliance and long-term effects of positive airway pressure (PAP) therapy on gas exchange, sleepiness, quality of life, depression and death rate in patients with obesity hypoventilation syndrome (OHS). Condition or disease Intervention/treatment Phase Obesity Hypoventilation Syndrome Device: Positive airway pressure (PAP) Not Applicable Detailed Description: Various forms of positive airway pressure (PAP) therapy

2018 Clinical Trials

198. Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy

-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Johns Hopkins University: bariatric endoscopy obesity metabolic syndrome gastric mucosal devitalization Endoscopic bariatric therapies Additional relevant MeSH terms: Layout table for MeSH terms Obesity Obesity, Morbid Overnutrition Nutrition Disorders Overweight Body Weight Signs and Symptoms (...) Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Part 2 - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

2018 Clinical Trials

199. Heat Therapy and Cardiometabolic Health in Obese Women

by a blinded investigator. Primary Purpose: Prevention Official Title: Heat Therapy and Cardiometabolic Health in Obese Women Actual Study Start Date : September 8, 2015 Actual Primary Completion Date : April 30, 2018 Actual Study Completion Date : July 1, 2018 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: Heat Therapy Subjects assigned to heat therapy underwent 30 1-hour hot tub sessions over 8-10 weeks (3 (...) Heat Therapy and Cardiometabolic Health in Obese Women Heat Therapy and Cardiometabolic Health in Obese Women - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Heat Therapy and Cardiometabolic Health in Obese

2018 Clinical Trials

200. High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - an observational cross-sectional study. Full Text available with Trip Pro

High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - an observational cross-sectional study. Poor nutritional status of patients with renal disease has been associated with worsening of renal function and poor health outcomes. Simply measuring weight and height for calculation of the body mass index does however not capture the true picture of nutritional status in these patients. Therefore, we measured nutritional status by BMI, body composition (...) , body composition measurement andfunctional measurements (hand grip strength). The prevalence of overweight and obesity, central obesity, sarcopenia, sarcopenic obesity and nutritional risk was calculated.Central obesity and sarcopenia were present in 49% and 35% of patients, respectively. 49% of patients with central obesity were normal weight or overweight according to their BMI. Factors associated with central obesity were a diagnosis of diabetes and increased fat mass, while factors associated

2018 BMC Nephrology

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