How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,422 results for

Normal Pressure Hydrocephalus

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

161. A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus

A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details

2012 Clinical Trials

162. Miethke proSA® adjustable gravitational shunt for hydrocephalus

it is recommended that no further research on behalf of HealthPACT is warranted at this time. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Cerebrospinal Fluid Shuntss; Drainage; Gravitation; Hydrocephalus; Hydrocephalus, Normal Pressure; Intracranial Pressure Language Published English Country of organisation Australia English summary An English language summary is available. Address for correspondence 199 Ward Street, North Adelaide SA 5006, Australia Tel: +61 8 8219 0900, Fax (...) Miethke proSA® adjustable gravitational shunt for hydrocephalus Miethke proSA® adjustable gravitational shunt for hydrocephalus Miethke proSA® adjustable gravitational shunt for hydrocephalus Australian Safety and Efficacy Register of New Interventional Procedures -Surgical (ASERNIP-S) Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation

2014 Health Technology Assessment (HTA) Database.

163. Diagnosis and management of idiopathic normal-pressure hydrocephalus Full Text available with Trip Pro

Diagnosis and management of idiopathic normal-pressure hydrocephalus The diagnosis and management of idiopathic normal-pressure hydrocephalus (iNPH), a disorder of gait impairment, incontinence, and dementia that affects elderly patients, incorporates an organized approach using familiar principles for neurologists. The starting point is a comprehensive history and neurologic examination, review of neuroimaging, and evaluation of the differential diagnosis. Coexisting disorders should

2013 Neurology: Clinical Practice

164. EEG and Neuronal Activity Topography analysis can predict effectiveness of shunt operation in idiopathic normal pressure hydrocephalus patients Full Text available with Trip Pro

EEG and Neuronal Activity Topography analysis can predict effectiveness of shunt operation in idiopathic normal pressure hydrocephalus patients Idiopathic normal pressure hydrocephalus (iNPH) is a neuropsychiatric syndrome characterized by gait disturbance, cognitive impairment and urinary incontinence that affect elderly individuals. These symptoms can potentially be reversed by cerebrospinal fluid (CSF) drainage or shunt operation. Prior to shunt operation, drainage of a small amount of CSF (...) or "CSF tapping" is usually performed to ascertain the effect of the operation. Unfortunately, conventional neuroimaging methods such as single photon emission computed tomography (SPECT) and functional magnetic resonance imaging (fMRI), as well as electroencephalogram (EEG) power analysis seem to have failed to detect the effect of CSF tapping on brain function. In this work, we propose the use of Neuronal Activity Topography (NAT) analysis, which calculates normalized power variance (NPV) of EEG

2013 NeuroImage : Clinical

165. The European iNPH Multicentre Study on the predictive values of resistance to CSF outflow and the CSF Tap Test in patients with idiopathic normal pressure hydrocephalus. (Abstract)

The European iNPH Multicentre Study on the predictive values of resistance to CSF outflow and the CSF Tap Test in patients with idiopathic normal pressure hydrocephalus. The objective was to determine the sensitivity, specificity, and positive and negative predictive values of the CSF Tap Test (CSF TT) and resistance to CSF outflow (Rout) for the outcome of shunting in a sample of patients with idiopathic normal pressure hydrocephalus (iNPH).115 patients were included in this European

2013 Neurosurgery and Psychiatry

166. Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery

Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Predictive Value (...) of Flow MRI in Normal Pressure Hydrocephalus Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01815775 Recruitment Status : Completed First Posted : March 21, 2013 Last Update Posted : March 21, 2013 Sponsor: Centre Hospitalier Universitaire, Amiens Information provided by (Responsible Party

2013 Clinical Trials

167. A Randomized Cross-over Study for Normal Pressure Hydrocephalus

A Randomized Cross-over Study for Normal Pressure Hydrocephalus A Randomized Cross-over Study for Normal Pressure Hydrocephalus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Randomized Cross-over Study (...) for Normal Pressure Hydrocephalus (ARCS NPH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01798641 Recruitment Status : Completed First Posted : February 26, 2013 Results First Posted : November 2, 2018 Last Update Posted : November 2, 2018 Sponsor: Johns Hopkins University Collaborators: Aesculap, Inc

2013 Clinical Trials

168. Flow MRI in Normal Pressure Hydrocephalus

Flow MRI in Normal Pressure Hydrocephalus Flow MRI in Normal Pressure Hydrocephalus - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Flow MRI in Normal Pressure Hydrocephalus (HydroFlux) The safety (...) Study Description Go to Brief Summary: Normal pressure hydrocephalus diagnosis based on quantitative study of cerebro-spinal fluid and blood flow by phase contrast magnetic resonance imaging. Condition or disease Intervention/treatment Phase Normal Pressure Hydrocephalus Other: Flow imaging Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 144 participants Allocation: Non-Randomized Intervention Model: Single Group

2013 Clinical Trials

169. Natural course of idiopathic normal pressure hydrocephalus. (Abstract)

Natural course of idiopathic normal pressure hydrocephalus. The natural course of idiopathic normal pressure hydrocephalus (iNPH) has not been thoroughly studied. The consequences of postponing shunt treatment are largely unknown. We aimed to describe the effects of waiting for more than 6 months before surgery and to compare the outcome with that seen in patients who waited for less than 3 months.33 patients (iNPHDelayed) underwent an initial investigation (Pre-op 1), followed by re

2013 Neurosurgery and Psychiatry

170. Predictors of subsequent overdrainage and clinical outcomes after ventriculoperitoneal shunting for idiopathic normal pressure hydrocephalus. Full Text available with Trip Pro

Predictors of subsequent overdrainage and clinical outcomes after ventriculoperitoneal shunting for idiopathic normal pressure hydrocephalus. Little is known about variables associated with overdrainage complications and neurofunctional and health-related quality of life outcomes in idiopathic normal-pressure hydrocephalus (iNPH) patients after shunt surgery.To identify candidate demographic and disease-specific predictors of overdrainage and patient-related outcomes, allowing for more

2013 Neurosurgery Controlled trial quality: uncertain

171. The callosal angle measured on MRI as a predictor of outcome in idiopathic normal-pressure hydrocephalus. Full Text available with Trip Pro

The callosal angle measured on MRI as a predictor of outcome in idiopathic normal-pressure hydrocephalus. Different neuroimaging biomarkers have been studied to find a tool for prediction of response to CSF shunting in idiopathic normal-pressure hydrocephalus (iNPH). The callosal angle (CA) has been described as useful in discriminating iNPH from ventricular dilation secondary to atrophy. However, the usefulness of the CA as a prognostic tool for the selection of shunt candidates among patients

2013 Journal of Neurosurgery

172. Association between Milder Brain Deformation before a Shunt Operation and Improvement in Cognition and Gait in Idiopathic Normal Pressure Hydrocephalus. (Abstract)

Association between Milder Brain Deformation before a Shunt Operation and Improvement in Cognition and Gait in Idiopathic Normal Pressure Hydrocephalus. We investigated the association between the degree of deformation of the brain before shunt operation and improvement of gait and cognitive impairment after shunt operation in 16 patients with idiopathic normal pressure hydrocephalus (iNPH). We evaluated gait and cognitive impairment and measured the cerebrospinal fluid volume in the ventricles

2013 Dementia and Geriatric Cognitive Disorders

173. Idiopathic normal-pressure hydrocephalus: Pathophysiology and diagnosis by CSF biomarkers. (Abstract)

Idiopathic normal-pressure hydrocephalus: Pathophysiology and diagnosis by CSF biomarkers. This observational study aimed to explore the pathophysiology of idiopathic normal-pressure hydrocephalus (iNPH) and to evaluate the diagnostic and prognostic value of CSF biomarkers.Lumbar CSF of patients with iNPH and healthy elderly individuals (HI) and ventricular CSF (VCSF) from the patients with iNPH pre and 6 months postsurgery were analyzed by ELISA. We analyzed neurofilament light protein (NFL

2013 Neurology

174. A reply to the letter to the editor regarding “microstructural changes of the corticospinal tract in idiopathic normal pressure hydrocephalus: a comparison of diffusion tensor and diffusional kurtosis imaging” Full Text available with Trip Pro

A reply to the letter to the editor regarding “microstructural changes of the corticospinal tract in idiopathic normal pressure hydrocephalus: a comparison of diffusion tensor and diffusional kurtosis imaging” 23989463 2014 06 19 2018 12 02 1432-1920 55 11 2013 Nov Neuroradiology Neuroradiology A reply to the letter to the editor regarding "microstructural changes of the corticospinal tract in idiopathic normal pressure hydrocephalus: a comparison of diffusion tensor and diffusional (...) kurtosis imaging". 1425 10.1007/s00234-013-1275-1 Hori Masaaki M Department of Radiology, Juntendo University School of Medicine, 2-1-1 Hongo Bunkyo-ku, Tokyo, 113-8421, Japan, mahori@juntendo.ac.jp. Nakanishi Atsushi A Aoki Shigeki S eng Letter Comment 2013 08 29 Germany Neuroradiology 1302751 0028-3940 IM Neuroradiology. 2013 Aug;55(8):971-6 23728069 Neuroradiology. 2013 Nov;55(11):1423-4 24005831 Diffusion Tensor Imaging methods Female Humans Hydrocephalus, Normal Pressure pathology Image

2013 Neuroradiology

175. Pulsatility in CSF dynamics: pathophysiology of idiopathic normal pressure hydrocephalus. Full Text available with Trip Pro

Pulsatility in CSF dynamics: pathophysiology of idiopathic normal pressure hydrocephalus. It is suggested that disturbed CSF dynamics are involved in the pathophysiology of idiopathic normal pressure hydrocephalus (INPH). The pulsatility curve describes the relationship between intracranial pressure (ICP) and the amplitude of cardiac related ICP pulsations. The position of baseline ICP on the curve provides information about the physiological state of the CSF dynamic system. The objective (...) of the study was to investigate if shunt surgery modifies the pulsatility curve and the baseline position on the curve, and how this relates to gait improvement in INPH.51 INPH patients were investigated with lumbar CSF dynamic investigations preoperatively and 5 months after shunt surgery. During the investigation, ICP was measured at baseline, and then a CSF sample was removed, resulting in pressure reduction. After this, ICP was regulated with an automated infusion protocol, with a maximum increase

2013 Neurosurgery and Psychiatry

176. Role of Endoscopic Third Ventriculostomy and Ventriculoperitoneal Shunt in Idiopathic Normal Pressure Hydrocephalus: Preliminary Results of a Randomized Clinical Trial. Full Text available with Trip Pro

Role of Endoscopic Third Ventriculostomy and Ventriculoperitoneal Shunt in Idiopathic Normal Pressure Hydrocephalus: Preliminary Results of a Randomized Clinical Trial. Currently, the most common treatment for idiopathic normal pressure hydrocephalus (INPH) is a ventriculoperitoneal shunt (VPS), generally with programmable valve implantation. Endoscopic third ventriculostomy (ETV) is another treatment option, and it does not require prosthesis implantation.To compare the functional neurological (...) based on the results of 6 clinical scales: mini-mental, Berg balance, dynamic gait index, functional independence measure, timed up and go, and normal pressure hydrocephalus.There was a statistically significant difference between the 2 groups after 12 months of follow-ups, and the VPS group showed better improvement results (ETV = 50%, VPS = 76.9%).Compared with ETV, VPS is a superior method because it had better functional neurological outcomes 12 months after surgery.

2013 Neurosurgery Controlled trial quality: uncertain

177. Improving Infant Hydrocephalus Outcomes in Uganda

in the general population is 10±3. Incidence of ETV/CPC treatment failure [ Time Frame: 6 months post-treatment ] Treatment failure or success will be determined with the use of clinical and radiographic criteria. Treatment success will be determined as the shift in the growth of head circumference to a normal rate, as plotted on a standard growth chart; decompression of the anterior fontanel; relief of symptoms of elevated intracranial pressure, such as irritability and vomiting; resolution of down-gaze (...) Improving Infant Hydrocephalus Outcomes in Uganda Improving Infant Hydrocephalus Outcomes in Uganda - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Improving Infant Hydrocephalus Outcomes in Uganda

2018 Clinical Trials

178. Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 1: Introduction and methodology

with results in patients with “normalpressure hydrocephalus were excluded if the study en- rolled fewer than 80% of the target patient population. • Studies that enrolled mixed patient populations were included only if separate results were reported for the target population. The results of the target population were the only results considered as evidence to sup- port our recommendations. • The study was a full article report of a clinical study. • The study was not a meeting abstract, editorial, letter (...) Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 1: Introduction and methodology J Neurosurg: Pediatrics / Volume 14 / November 2014 J Neurosurg Pediatrics (Suppl) 14:3–7, 2014 3 ©AANS, 2014 P ediatric hydrocephalus is the most common surgi- cally correctable neurological problem in infants, children, and adolescents. It is estimated that hy- drocephalus may occur with the frequency of 1 in every 500 children. There are multiple causes of this disorder

2014 Congress of Neurological Surgeons

179. Noninvasive Intracranial Pressure and Hydrocephalus Patients

Noninvasive Intracranial Pressure and Hydrocephalus Patients Noninvasive Intracranial Pressure and Hydrocephalus Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Noninvasive Intracranial Pressure (...) Study Details Study Description Go to Brief Summary: Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries. Patients with hydrocephalus are typically treated with a shunt in order to reduce ICP. At times the shunt can malfunction. We believe that our algorithm will help identify when a hydrocephalus patient's shunt has malfunctioned. Condition or disease Intervention/treatment Hydrocephalus Device

2015 Clinical Trials

180. Role of cerebral spinal fluid (CSF) flow measured by magnetic resonance imaging (MRI) as a diagnostic biomarker of Normal Pressure Hydrocephalus (NPH)

Role of cerebral spinal fluid (CSF) flow measured by magnetic resonance imaging (MRI) as a diagnostic biomarker of Normal Pressure Hydrocephalus (NPH) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2015 PROSPERO

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>