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Nonocclusive Mesenteric Ischemia

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1. Establishment of Predictive Models for Nonocclusive Mesenteric Ischemia Comparing 8,296 Control with 452 Study Patients. (Abstract)

Establishment of Predictive Models for Nonocclusive Mesenteric Ischemia Comparing 8,296 Control with 452 Study Patients. The aim of this study was to develop clinical preoperative, intraoperative, and postoperative scores for early identification of patients who are at risk of nonocclusive mesenteric ischemia (NOMI).A retrospective analysis.Single center.From January 2008 to December 2014, all patients from the Department of Thoracic and Cardiovascular Surgery were included on the basis (...) of the hospital database.All mesenteric angiographically identified NOMI patients were compared with non-NOMI patients.The study population of 8,748 patients was randomized into a cohort for developing the scores (non-NOMI 4,214 and NOMI 235) and a cohort for control (non-NOMI 4,082 and NOMI 217). Risk factors were identified using forward and backward Wald test and were included in the predictive scores for the occurrence of NOMI. C statistic showed that the scores had a high discrimination

2019 Journal of cardiothoracic and vascular anesthesia Controlled trial quality: uncertain

2. A Case of Septicemia due to Nonocclusive Mesenteric Ischemia Occurring in Induction Chemotherapy Full Text available with Trip Pro

A Case of Septicemia due to Nonocclusive Mesenteric Ischemia Occurring in Induction Chemotherapy In nonocclusive mesenteric ischemia (NOMI), mesenteric ischemia and intestinal necrosis occur despite the absence of organic blockage in mesenteric blood vessels. As abdominal pain is often absent and few characteristic findings are seen in blood biochemistry, imaging diagnosis or other examinations, discovery is often delayed. With a mortality rate of 56-79%, NOMI is a very serious disease. However

2018 Case reports in otolaryngology

3. Treatment of nonocclusive mesenteric ischemia with type B aortic dissection using intra-arterial catheterization after trauma surgery: case report Full Text available with Trip Pro

Treatment of nonocclusive mesenteric ischemia with type B aortic dissection using intra-arterial catheterization after trauma surgery: case report Nonocclusive mesenteric ischemia (NOMI) is a mesenteric arterial spasm and intestinal ischemia. This disease is a highly lethal disease because diagnosis and decision of appropriate treatments are often difficult. Operations cannot resolve the spasms and may worsen the situation. However, the safety and effectiveness of catheterization for NOMI (...) with aortic dissection (AD) have not yet been elucidated. Here, we report a successful case of early diagnosis and treatment of NOMI with type B AD involving the superior mesenteric artery (SMA) using the intra-arterial infusion of a vasodilator via the SMA.An 83-year-old man was admitted to our hospital because of abdominal pain after a motor accident. We performed intestinal resection and splenectomy for intestinal perforation and splenic hemorrhage and treated conservatively for acute AD, liver injury

2018 Surgical Case Reports

4. Presepsin and Inflammatory Markers Correlate With Occurrence and Severity of Nonocclusive Mesenteric Ischemia After Cardiovascular Surgery. (Abstract)

Presepsin and Inflammatory Markers Correlate With Occurrence and Severity of Nonocclusive Mesenteric Ischemia After Cardiovascular Surgery. To prospectively evaluate the relationship of established inflammatory markers and presepsin on nonocclusive mesenteric ischemia and to correlate presepsin levels to the occurrence and severity of nonocclusive mesenteric ischemia.Patients were prospectively enrolled and blood samples taken, followed by a retrospective evaluation of laboratory values (...) and angiographic findings. The study was ethics committee approved.Patients with clinical suspicion of nonocclusive mesenteric ischemia underwent catheter angiography of the superior mesenteric artery. Images were assessed by two experienced radiologists on consensus basis using a previously published standardized reporting system (Homburg-Nonocclusive Mesenteric Ischemia-Score). Two groups were formed according to the severity of nonocclusive mesenteric ischemia, mild and severe, patients without clinical

2018 Critical Care Medicine

5. Protein-losing enteropathy secondary to nonocclusive mesenteric ischemia: A case report. Full Text available with Trip Pro

Protein-losing enteropathy secondary to nonocclusive mesenteric ischemia: A case report. Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder; prompt diagnosis is vital. Surgical treatment is often required, but some cases can be treated conservatively. We herein report an extremely rare case wherein protein-losing enteropathy (PLE) developed after conservative treatment of NOMI.The patient was a 66-year-old man. He underwent laparoscopic super low anterior resection

2018 Medicine

6. Detection of patients at high risk for nonocclusive mesenteric ischemia after cardiovascular surgery Full Text available with Trip Pro

Detection of patients at high risk for nonocclusive mesenteric ischemia after cardiovascular surgery Nonocclusive mesenteric ischemia (NOMI) is a rare but life-threatening complication after cardiovascular surgery. Early diagnosis and treatment is essential for a chance to cure. The aim of this study is to identify the independent risk factors for NOMI based on the evaluation of 12 cases of NOMI after cardiovascular surgery.We retrospectively analyzed 12 patients with NOMI and 674 other

2018 Journal of cardiothoracic surgery

7. Successfully Treated Nonocclusive Mesenteric Ischemia After Transcatheter Aortic Valve Replacement. Full Text available with Trip Pro

Successfully Treated Nonocclusive Mesenteric Ischemia After Transcatheter Aortic Valve Replacement. An 80-year-old man with symptomatic severe aortic stenosis underwent transcatheter aortic valve replacement. Postoperatively, the patient was hemodynamically stable without inotropic or mechanical support. Approximately 30 hours after the procedure, he developed severe abdominal pain, and a blood test result showed elevated serum lactate level. We suspected nonocclusive mesenteric ischemia (...) and performed emergency selective angiography of the superior mesenteric artery, which showed vasospasm. We confirmed the diagnosis of nonocclusive mesenteric ischemia, and it was treated successfully with intraarterial infusion of vasodilators into the superior mesenteric artery.Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

2017 Annals of Thoracic Surgery

8. Risk factor analysis for nonocclusive mesenteric ischemia following cardiac surgery: A case-control study. Full Text available with Trip Pro

Risk factor analysis for nonocclusive mesenteric ischemia following cardiac surgery: A case-control study. Although rare, postcardiac surgery nonocclusive mesenteric ischemia (NOMI) is a life-threatening condition. Identifying the risk factors for NOMI during immediate postoperative period may help early detection and intervention, which leads to improved clinical outcomes. The objective of this study was to identify the clinical features and risk factors of NOMI for prognosis identification

2017 Medicine

9. Successful treatment of nonocclusive mesenteric ischemia after aortic valve replacement with continuous arterial alprostadil infusion: A case report Full Text available with Trip Pro

Successful treatment of nonocclusive mesenteric ischemia after aortic valve replacement with continuous arterial alprostadil infusion: A case report Nonocclusive mesenteric ischemia (NOMI) after surgery has an extremely poor prognosis with a mortality rate of 30-100%. We report a patient with NOMI following aortic valve replacement who failed to improve despite continuous intra-arterial infusion of papaverine, but was successfully treated with alprostadil (prostaglandin E1 [PGE1]) infusion.The (...) patient is a 77-year-old man who underwent aortic valve replacement. Due to elevated serum lactate levels five hours after intensive care unit admission, superior mesenteric arteriography was performed, establishing the diagnosis of NOMI. Although continuous intra-arterial infusion of papaverine was begun, lactate levels remained elevated. Repeat angiography and laparotomy revealed extensive ischemic changes of the intestine. The vasodilator was changed to PGE1, which improved arterial spasm

2017 International journal of surgery case reports

10. Nonocclusive Mesenteric Ischemia

are present IX. Prognosis: Outcomes Reversible ischemia in 44% of cases Persistent colitis in 19% of cases Ischemic stricture in 13% of cases Perforation or gangrene in 19% of cases X. References Fraboni (2012) Board Review Express, San Jose Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Nonocclusive Mesenteric Ischemia." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip (...) Database) Ontology: Non-occlusive mesenteric ischemia (C0341422) Concepts Disease or Syndrome ( T047 ) SnomedCT 235843005 English Non-occl mesenteric ischaemia , Non-occl mesenteric ischemia , NOMI - Non-occl mesent ischaem , Non-occlusive mesenteric ischaemia , Non-occlusive mesenteric ischemia , NOMI - Non-occlusive mesenteric ischaemia , NOMI - Non-occlusive mesenteric ischemia , Non-occlusive mesenteric ischemia (disorder) Spanish isquemia mesentérica no oclusiva (trastorno) , isquemia mesentérica

2018 FP Notebook

11. Imaging of Mesenteric Ischemia

with diffuse atherosclerotic disease [5]. Pathophysiology Acute mesenteric ischemia is most commonly secondary to acute embolism to the superior mesenteric artery (SMA), which accounts for approximately 40% to 50% of all episodes. Acute mesenteric artery thrombosis is the second most common cause of acute mesenteric ischemia (20%–30%) followed by nonocclusive mesenteric ischemia (25%) and, less commonly, mesenteric and portal venous thrombosis (5%–15%). In the chronic setting, mesenteric ischemia is almost (...) collateral circulation is commonly present. Nonocclusive mesenteric ischemia is seen in the setting of hypoperfusion because of secondary vasoconstriction of the mesenteric arteries. In these cases, there is no evidence of vascular occlusion, and the ischemia is distributed over a wider area of the bowel in a nonconsecutive manner [9]. Mesenteric and portal venous thrombosis is the least common cause of acute mesenteric ischemia and may be idiopathic. Most common risk factors are hypercoagulable states

2018 American College of Radiology

12. Vasopressin As Therapy During Nonocclusive Mesenteric Ischemia. Full Text available with Trip Pro

Vasopressin As Therapy During Nonocclusive Mesenteric Ischemia. Vasopressin is used as an adjunct to norepinephrine to support blood pressure in vasodilatory shock after cardiopulmonary bypass (CPB). In this study, we report our observation of vasopressin treatment in 11 patients with nonocclusive mesenteric ischemia (NOMI).In an observational cohort study, 78 patients were studied after having been treated for NOMI with intraarterial iloprost infusion after elective cardiac operation. All (...) by mesenteric angiography.Before initiation of NOMI treatment Vaso patients had significantly higher doses of norepinephrine than the Nor patients (Vaso, 0.65 ± 0.20 μg · kg(-1) · min(-1); Nor, 0.20 ± 0.13 μg · kg(-1) · min(-1); p < 0.001), and their diagnostic score of the angiography was higher (Vaso, 5.4 ± 1.1 points; Nor, 3.5 ± 2.1 points; p = 0.004). After 2 days of NOMI treatment, Vaso patients had improved intestinal perfusion in the control angiography (Vaso, 3.8 ± 1.5 points) and significantly

2016 Annals of Thoracic Surgery

13. Nonocclusive mesenteric ischemia: fulminant pancolitis Full Text available with Trip Pro

Nonocclusive mesenteric ischemia: fulminant pancolitis NOMI is mesenteric hypoperfusion with reactive vascular spasms. Changes in the color of the mucosa may reflect the severity of the ischemia of the colon and the severity of prognosis. Even with surgery, the mortality rate is 75%. Diagnosis requires a high degree of clinical suspicion.

2016 Clinical Case Reports

14. Delayed intestinal stenosis of nonocclusive mesenteric ischemia after autologous blood collection: A case report Full Text available with Trip Pro

Delayed intestinal stenosis of nonocclusive mesenteric ischemia after autologous blood collection: A case report Nonocclusive mesenteric ischemia (NOMI) has been reported to be associated with high mortality. Early diagnosis of NOMI and prompt restoration of the intestinal blood flow is necessary in order to achieve a favorable outcome.We present the case of a patient who developed NOMI after autologous blood collection and was treated by selective infusion of the superior mesenteric artery (...) with papaverine, intestinal decompression using a long intestinal tube, the administration of antibiotics, and fluid replacement. Although this non-surgical management was successful, 8 weeks after the ischemic event, segmental bowel resection was necessary because of repeated intestinal obstruction caused by bowel stricture.Autologous blood collection might be a risk factor of NOMI. In addition, the possibility of delayed intestinal stenosis remains, even if bowel necrosis and surgical resection were avoided

2016 International journal of surgery case reports

15. Elevated Procalcitonin in Patients After Cardiac Surgery: A Hint to Nonocclusive Mesenteric Ischemia. (Abstract)

Elevated Procalcitonin in Patients After Cardiac Surgery: A Hint to Nonocclusive Mesenteric Ischemia. Nonocclusive mesenteric ischemia (NOMI) can occur after cardiac surgery, commonly in conjunction with use of cardiopulmonary bypass. Some evidence suggests that serum procalcitonin (PCT) levels are increased in patients with mesenteric ischemia; however, an association between PCT and NOMI has not yet been studied. The current study investigates whether elevated serum PCT levels are found

2015 Annals of Thoracic Surgery

16. Radiologic Management of Mesenteric Ischemia

of acute embolus (if peritoneal signs are absent), percutaneous transluminal angioplasty (PTA), and stent placement for patients with chronic arterial occlusive disease. Acute nonocclusive mesenteric ischemia (NOMI) can be managed by intra-arterial administration of vasodilators, such as nitroglycerin or papaverine, or by high-dose intravenous prostaglandin E1. First-line treatment for venous mesenteric ischemia is systemic anticoagulation. 1 Principal Author, University of California San Francisco (...) to the presence of vasospasm associated with occlusive mesenteric ischemia, catheter-directed vasodilator infusion may also be of benefit in some patients with occlusive mesenteric ischemia, especially prior to more definitive therapy. Treatment of underlying stenotic or occlusive lesions using PTA/S can be achieved at the same setting as diagnosis, sometimes after removal of a thrombotic clot by aspiration or thrombolysis [11]. Variant 3: Acute Nonocclusive Mesenteric Ischemia In a patient with signs

2016 American College of Radiology

17. Prognostic factors of acute mesenteric ischemia in ICU patients. Full Text available with Trip Pro

, severity scores. The 30-day mortality rate was 71% for the 214 patients with arterial AMI. The incidence of nonocclusive mesenteric ischemia was particularly high. AMI was a secondary diagnosis in 58% of patients. Half of the population was represented by surgical patients who mostly required an urgent procedure. The mortality rate was not different in the subgroup with aortic surgery. Three factors were associated with an increase or decrease in mortality: the maximal dose of vasopressors (VP (...) Prognostic factors of acute mesenteric ischemia in ICU patients. The primary endpoint was to investigate the prognostic factors of acute mesenteric ischemia (AMI) in ICU patients.Retrospective observational, non-interventional, monocentric study of a cohort of 214 ICU patients with a confirmed diagnosis of arterial AMI.We collected demographics, mortality, hospital stay, prior medical history, comorbidities, reasons for ICU admission, laboratory investigations, diagnostic procedures, therapy

2019 BMC Gastroenterology

18. Elevated endothelin-1 level is a risk factor for nonocclusive mesenteric ischemia. Full Text available with Trip Pro

Elevated endothelin-1 level is a risk factor for nonocclusive mesenteric ischemia. Nonocclusive mesenteric ischemia may occur after cardiac surgery, commonly in conjunction with the use of cardiopulmonary bypass. Some evidence suggests that endothelin-1 serum levels are increased in patients with mesenteric ischemia, but the association of endothelin-1 and nonocclusive mesenteric ischemia has not been studied. The objective was to investigate whether elevated levels of endothelin-1 could (...) be found in patients exhibiting nonocclusive mesenteric ischemia.In an observational cohort study, nonocclusive mesenteric ischemia developed in 78 of 865 patients undergoing elective cardiac surgery. Control patients were identified from the cohort through 1:1 propensity score matching. Preoperative and postoperative endothelin-1 serum levels were determined by means of enzyme-linked immunosorbent assay. Odds ratios (with 95% confidence interval) were calculated by logistic regression analyses

2014 Journal of Thoracic and Cardiovascular Surgery

19. Nonocclusive mesenteric ischemia following multiple wasp stings. (Abstract)

Nonocclusive mesenteric ischemia following multiple wasp stings. Massive wasp envenomation can cause not only severe immediate allergic reactions and anaphylaxis but also severe delayed toxin-mediated systemic reactions, including hemolysis, coagulopathy, rhabdomyolysis, acute renal failure, and hepatotoxicity. However, reports of the latter type of reactions are rare. The subject of this case report, a 66-year-old man, was stung more than 30 times during an attack by wasps. Although he (...) or emboli but did reveal the abrupt tapering of mesenteric arteries, strongly suggested that the ischemia was due to nonocclusive mesenteric ischemia. Immediately after diagnosis, an emergency laparotomy was performed. Nonocclusive mesenteric ischemia was finally diagnosed via a histologic examination of the resected small bowel. We present the first case report of nonocclusive mesenteric ischemia consequent to wasp stings.

2014 American Journal of Emergency Medicine

20. Idiopathic Myointimal Hyperplasia of Mesenteric Veins: An Uncommon Cause of Ischemic Colitis With Distinct Mucosal Features. Full Text available with Trip Pro

Idiopathic Myointimal Hyperplasia of Mesenteric Veins: An Uncommon Cause of Ischemic Colitis With Distinct Mucosal Features. Idiopathic myointimal hyperplasia of mesenteric veins causes chronic ischemic mucosal injury with segmental strictures that mimic inflammatory bowel disease and nonocclusive ischemic colitis. It is characterized by myointimal proliferative changes that narrow the lumina of veins combined with ischemic injury and ulcers. Most cases reported to date have been diagnosed (...) , nonocclusive ischemia, Crohn disease, diverticulitis, and mucosal amyloidosis, and 5 cases of small vessel (leukocytoclastic) vasculitis. Study patients were mostly older men with distal colorectal disease. All resection specimens showed mucosal ischemia with numerous thick-walled (arteriolized) capillaries and glassy subendothelial fibrin deposits; numerous hyalinized, eosinophilic thrombi were detected in 90% of colectomy specimens. Biopsies showed arteriolized capillaries (100%), subendothelial fibrin

2017 American Journal of Surgical Pathology

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