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Newborn Exam

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1. Newborn and infant physical examination: programme handbook

) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Details The purpose of this handbook is to inform and support best clinical practice in the NHS newborn and infant physical examination ( 27 August 2019 Updated NIPE programme handbook. 24 April 2018 Updated pathway appendices in accessible PDF formats. 19 April 2018 Minor correction to neonatal hip risk factors under Standard (...) Newborn and infant physical examination: programme handbook Newborn and infant physical examination: programme handbook - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search The United Kingdom is leaving the European Union on 31 October 2019. Guidance Newborn and infant physical examination: programme handbook This document brings together all the guidelines that relate to the NHS newborn and infant physical

2019 Public Health England

2. Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight Full Text available with Trip Pro

Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight Medical nutrition therapy is a mainstay of gestational diabetes mellitus (GDM) treatment. However, data are limited regarding the optimal diet for achieving euglycemia and improved perinatal outcomes. This study aims to investigate whether modified dietary interventions (...) interventions when compared with control subjects, there was a larger decrease in fasting and postprandial glucose (-4.07 mg/dL [95% CI -7.58, -0.57]; P = 0.02 and -7.78 mg/dL [95% CI -12.27, -3.29]; P = 0.0007, respectively) and a lower need for medication treatment (relative risk 0.65 [95% CI 0.47, 0.88]; P = 0.006). For neonatal outcomes, analysis of 16 randomized controlled trials including 841 participants showed that modified dietary interventions were associated with lower infant birth weight

2018 EvidenceUpdates

3. AIUM Practice Parameter for the Performance of an Ultrasound Examination of the Neonatal and Infant Spine

has been developed to assist practitioners in the performance of neonatal and infant spine sonography. In some cases, an additional or specialized examination may be necessary. While it is not possible to detect every abnormality, following this practice parameter will maximize the detection of abnormalities of the infant spine. Sonographic exam- ination of the pediatric spinal canal is accomplished by scanning through the normally incom- pletely ossified posterior elements. Therefore, it is most (...) successful in the newborn period and in early infancy. In infants older than 6 months, the examination can be very limited, although the level of termination of the cord can often be identified. In experienced hands, ultrasound imaging of the infant spine has been shown to be an accurate and cost-effective examination that is comparable to magnetic resonance imaging (MRI) for evaluating congenital or acquired abnormalities in the neonate and young infant. Because of the clinical ease of examination

2016 American Institute of Ultrasound in Medicine

4. Effect of Eye Masks on Neonatal Stress Following Dilated Retinal Examination: The MASK-ROP Randomized Clinical Trial. (Abstract)

Effect of Eye Masks on Neonatal Stress Following Dilated Retinal Examination: The MASK-ROP Randomized Clinical Trial. Although screening examinations for retinopathy of prematurity (ROP) prevent blindness, they are physiologically stressful for infants. Photosensitivity during mydriasis may contribute to postexamination stress, and reducing light stimulation may make infants more comfortable.To determine the effect of a phototherapy mask worn during mydriasis on infant stress in the 12-hour (...) period following ROP screening.The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination (MASK-ROP) randomized clinical trial with patient recruitment from April 2016 to June 2017 at neonatal intensive care units at St Michael's Hospital and Sunnybrook Health Sciences Center in Toronto, Ontario, Canada. A consecutive series of infants with birth weight of less than 1500 g and/or gestational age of less than 32 weeks undergoing their first ROP screening were analyzed beginning

2019 JAMA ophthalmology

5. Two-stage approach for prediction of small-for-gestational-age neonate and adverse perinatal outcome by routine ultrasound examination at 35-37 weeks' gestation. (Abstract)

Two-stage approach for prediction of small-for-gestational-age neonate and adverse perinatal outcome by routine ultrasound examination at 35-37 weeks' gestation. Justification of prenatal screening for small-for-gestational-age (SGA) fetuses near term is based on, first, evidence that such fetuses/neonates are at increased risk of stillbirth and adverse perinatal outcome, and, second, the expectation that these risks can be reduced by medical interventions, such as early delivery. However (...) , there are no randomized studies demonstrating that routine screening for SGA fetuses and appropriate interventions in the high-risk group can reduce adverse perinatal outcome. Before such meaningful studies can be undertaken, it is essential that the best approach for effective identification of SGA neonates is determined, and that the contribution of SGA neonates to the overall rate of adverse perinatal outcome is established. In a previous study of pregnancies undergoing routine ultrasound examination at 35 + 0

2019 Ultrasound in Obstetrics and Gynecology

6. Examining Endocrine Disruptors Measured in Newborn Dried Blood Spots and Early Childhood Growth in a Prospective Cohort. Full Text available with Trip Pro

Examining Endocrine Disruptors Measured in Newborn Dried Blood Spots and Early Childhood Growth in a Prospective Cohort. The goal of this study was to determine whether newborn concentrations of perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and bisphenol A (BPA) are associated with early childhood growth.A total of 1,954 singletons and 966 twins from the Upstate KIDS Study (born 2008-2010) were included in this study. Newborn dried blood spot concentrations of PFOS, PFOA (...) levels were higher among neonates with a neonatal intensive care unit stay (P < 0.001), making associations difficult to interpret.Perfluorinated alkyl substances did not exhibit obesogenic associations with early measures of childhood growth. Blood-based BPA measures are limited by the nonpersistent nature of the chemical, and unknown sources from hospital settings may present only transient exposures.© 2018 The Obesity Society.

2019 Obesity

7. Oral sweet solution to prevent pain during neonatal hip examination: a randomised controlled trial. Full Text available with Trip Pro

Oral sweet solution to prevent pain during neonatal hip examination: a randomised controlled trial. To determine if oral glucose can have a pain-relieving effect during routine hip examinations in newborn infants.In this randomised controlled study 100 newborn infants undergoing the routine physical examination including the potentially painful hip examination were included between March 2016 and April 2017. Fifty infants were randomised to water (control) and 50 to oral glucose (intervention (...) ).Oral glucose given before the examination has a pain-relieving effect during the hip examination in healthy newborn infants.© 2018 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.

2018 Acta paediatrica (Oslo, Norway : 1992) Controlled trial quality: uncertain

8. Outbreak of Adenovirus in a Neonatal Intensive Care Unit: Critical Importance of Equipment Cleaning During Inpatient Ophthalmologic Examinations. Full Text available with Trip Pro

Outbreak of Adenovirus in a Neonatal Intensive Care Unit: Critical Importance of Equipment Cleaning During Inpatient Ophthalmologic Examinations. Outbreaks of adenovirus in neonatal intensive care units (NICUs) can lead to widespread transmission and serious adverse outcomes. We describe the investigation, response, and successful containment of an adenovirus outbreak in a NICU associated with contaminated handheld ophthalmologic equipment used during retinopathy of prematurity (ROP (...) (PCR) and partial- and whole-genome sequencing assays were used for testing of clinical and environmental specimens.We identified 23 primary neonatal cases and 9 secondary cases (6 employees and 3 parents). All neonatal case-patients had respiratory symptoms. Of these, 5 developed pneumonia and 12 required increased respiratory support. Less than half (48%) had ocular symptoms. All neonatal case-patients (100%) had undergone a recent ophthalmologic examination, and 54% of neonates undergoing

2018 Ophthalmology

9. Examining the utility of the CD64 index compared with other conventional indices for early diagnosis of neonatal infection Full Text available with Trip Pro

Examining the utility of the CD64 index compared with other conventional indices for early diagnosis of neonatal infection As specific clinical manifestations and detection tools for early neonatal infections are lacking, early detection and treatment are ongoing challenges. The present study aimed to investigate the role and clinical significance of the CD64 index in comparison with conventional examination indices (WBC, PCT and CRP) for the early diagnosis of neonatal infection. Of 74 (...) in-patient newborns, non-sepsis (non-specific infection but free of sepsis), sepsis and control [newborns with ABO hemolytic disease of the newborn (ABOHDN) but without infection] groups involved 32, 16 and 26 cases, respectively. Peripheral blood WBC, PCT, CRP and CD64 indices were acquired for all groups. The sepsis group showed significantly higher WBC, PCT and CRP levels than the control group. Compared with the non-sepsis group, the sepsis group demonstrated significant increases in PCT

2018 Scientific reports

10. Neonatal, infant and under-five mortalities in Nigeria: An examination of trends and drivers (2003-2013). Full Text available with Trip Pro

Neonatal, infant and under-five mortalities in Nigeria: An examination of trends and drivers (2003-2013). Neonatal (NMR), infant (IMR) and under-five (U5M) mortality rates remain high in Nigeria. Evidence-based knowledge of trends and drivers of child mortality will aid proper interventions needed to combat the menace. Therefore, this study assessed the trends and drivers of NMR, IMR, and U5M over a decade in Nigeria. A nationally representative data from three consecutive Nigeria Demographic (...) , 41, 39; 100, 75, 69; and 201, 157, 128 respectively. The NMR, IMR, and U5M were consistently lower among children whose mothers were younger, living in rural areas and from richer households. Generally, the probability of neonate death in 2003, 2008 and 2013 were 0.049, 0.039 and 0.038 respectively, the probability of infant death was 0.093, 0.071 and 0.064 while the probability of under-five death was 0.140, 0.112 and 0.092 for the respective survey years. While adjusting for other variables

2017 PLoS ONE

11. A Prospective Cohort Study Examining the Association Between Maternal Arsenic Exposure, Fetal Loss, and Neonatal Mortality. Full Text available with Trip Pro

A Prospective Cohort Study Examining the Association Between Maternal Arsenic Exposure, Fetal Loss, and Neonatal Mortality. Arsenic crosses the placenta, possibly increasing the risk of adverse reproductive outcomes. We aimed to examine the association between maternal arsenic exposure and fetal/neonatal survival using data from a prospective cohort study of 1,616 maternal-infant pairs recruited at a gestational age of ≤16 weeks in Bangladesh (2008-2011). Arsenic concentration in maternal (...) drinking water was measured at enrollment. Extended Cox regression (both time-dependent coefficients and step functions) was used to estimate the time-varying association between maternal arsenic exposure and fetal/neonatal death (all mortality between enrollment and 1 month after birth). In a sensitivity analysis, we assessed gestational arsenic exposure using maternal urine samples taken at enrollment. We observed 203 fetal losses and 20 neonatal deaths. Higher arsenic exposure was associated

2018 American Journal of Epidemiology

12. Oral Sweet Solution to Prevent Pain During Neonatal Hip Examination

Oral Sweet Solution to Prevent Pain During Neonatal Hip Examination Oral Sweet Solution to Prevent Pain During Neonatal Hip Examination - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Oral Sweet Solution (...) to Prevent Pain During Neonatal Hip Examination The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03486015 Recruitment Status : Completed First Posted : April 3, 2018 Last Update Posted : April 3, 2018 Sponsor: Region Örebro County Information provided by (Responsible Party): Region Örebro County Study

2018 Clinical Trials

13. Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study. (Abstract)

of prematurity, abnormal fundus pigmentation, subconjunctival haemorrhage, choroidal coloboma, idiopathic retinal venous tortuosity, exudative changes and other anomalies with uncertain identities.This large-scale study of newborn fundus examination showed a relatively high prevalence of ocular abnormalities. Hundreds of neonates with rare disorders that severely impair ocular health were also detected at an early age. The long-term impact of other anomalies including RHs on the ocular system should (...) Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study. The prevalence of ocular abnormalities of newborn in China has seldom been reported. To report the implementation of digital imaging in ocular screening of all newborns in multiple centres in China and to describe the abnormal findings of fundus examination, we did the cross-sectional study.Fundus examinations were performed on newborns within the 42 days after birth using a RetCam wide

2018 British Journal of Ophthalmology

14. A Cross-Sectional Assessment of Cutaneous Lumbosacral and Coccygeal Physical Examination Findings in a Healthy Newborn Population Full Text available with Trip Pro

A Cross-Sectional Assessment of Cutaneous Lumbosacral and Coccygeal Physical Examination Findings in a Healthy Newborn Population Objective. The purpose of this study is to describe the range and frequency of cutaneous lumbosacral and coccygeal findings encountered during the newborn examination in a population of apparently healthy babies, to determine if the prevalence of these findings is associated with race/ethnicity, and to report the frequency of co-occurrence of low-risk cutaneous (...) findings. Methods. Lumbosacral physical findings of 1121 infants were documented on well newborns at least 35 weeks or greater gestational age under the authors' care. The overall frequency of each physical finding was tabulated in addition to determining whether frequencies varied by race/ethnicity. Co-occurrence of the most common physical findings was also examined. Results. Of 1096 infants included in the study, 24.8% had deviated or duplicated gluteal creases, 15.6% had dimples, and 24.7% had

2018 Global pediatric health

15. A Comparison of Breast Milk and Sucrose in Reducing Neonatal Pain During Eye Exam for Retinopathy of Prematurity. (Abstract)

A Comparison of Breast Milk and Sucrose in Reducing Neonatal Pain During Eye Exam for Retinopathy of Prematurity. This double-blind randomized controlled experimental study aimed to determine the effects of breast milk and sucrose in reducing pain in preterm infants during retinopathy of prematurity (ROP) examination.This study was conducted with 60 preterm infants (breast milk group = 20, sucrose group = 20, and control/distilled water group = 20) meeting the inclusion criteria. The data were (...) collected with the use of an Infant Evaluation Form, Procedure Monitoring Form, and Premature Infant Pain Profile (PIPP). The preterm infants were provided with 1 mL of breast milk, sucrose, and distilled water before the ROP examination. The pain level in preterm infants was measured by the PIPP 5 minutes before, during, and 5 minutes after the ROP examination. The ROP examinations were video recorded, and videos were evaluated by three observers blinded to the study.No significant difference

2018 Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine Controlled trial quality: uncertain

16. Examining the Effects of Prenatal Education

maternal and neonatal outcomes. Cochrane Database of Systematic Reviews 2015(12): Cd009916. Examining the Effects of Prenatal Education 14 Evidence >> Insight >> Action 36. Downe S, Finlayson K, Tuncalp, Metin Gulmezoglu A. What matters to women: A systematic scoping review to identify the processes and outcomes of antenatal care provision that are important to healthy pregnant women. British Journal of Obstetrics and Gynecology 2016; 123(4): 529-39. 37. Lawford K, Giles A. Kivalliq Inuit Centre (...) Examining the Effects of Prenatal Education EVIDENCE INSIGHT ACTION >> >> 8 JUNE 2017 HEALTH FORUM Rapid Synthesis Examining the Effects of Prenatal Education 27 September 2019McMaster Health Forum 1 Evidence >> Insight >> Action Rapid Synthesis: Examining the Effects of Prenatal Education 30-day response 27 September 2019 Examining the Effects of Prenatal Education 2 Evidence >> Insight >> Action McMaster Health Forum The McMaster Health Forum’s goal is to generate action on the pressing

2020 McMaster Health Forum

17. Examining Perceptions of Computerized Physician Order Entry in a Neonatal Intensive Care Unit Full Text available with Trip Pro

Examining Perceptions of Computerized Physician Order Entry in a Neonatal Intensive Care Unit Computerized provider order entry (CPOE) is a technology with potential to transform care delivery. While CPOE systems have been studied in adult populations, less is known about the implementation of CPOE in the neonatal intensive care unit (NICU) and perceptions of nurses and physicians using the system.To examine perceptions of clinicians before and after CPOE implementation in the NICU

2017 Applied clinical informatics

18. Re-examining the arterial cord blood gas pH screening criteria in neonatal encephalopathy. Full Text available with Trip Pro

Re-examining the arterial cord blood gas pH screening criteria in neonatal encephalopathy. Screening criteria for neonatal encephalopathy remain a complex combination of subjective and objective criteria. We examine the utility of universal cord blood gas testing and mandatory encephalopathy evaluation for infants with pH ≤7.10 on umbilical cord arterial blood gas (cABG) as a single screening measure for timely identification of moderate/severe encephalopathy.Infants born at a single centre (...) between 2008 and 2015, who were ≥36 weeks, had no congenital anomalies and had a cABG pH ≤7.10 were identified for a retrospective cohort study. Maternal/perinatal and patient factors were collected.27 028 infants were born during the study period; 412 met all inclusion criteria. Of those, 35/85 infants with pH <7.00 and 34/327 infants with pH between 7.00 and 7.10 had moderate/severe encephalopathy. Encephalopathy was identified on the basis of pH and examination alone (no other perinatal criteria

2017 Archives of Disease in Childhood. Fetal and Neonatal Edition

19. Why gone too soon? Examining social determinants of neonatal deaths in northwest Ethiopia using the three delay model approach. Full Text available with Trip Pro

Why gone too soon? Examining social determinants of neonatal deaths in northwest Ethiopia using the three delay model approach. Without improving the survival of newborns, meaningful reduction in under-five mortality is difficult. Most neonatal deaths are preventable when appropriate and timely care is sought. In Ethiopia, there is lack of evidence on the type and contribution of delays in treatment seeking to neonatal deaths.A community based social autopsy (SA) of 39 neonatal deaths (...) was conducted from March 16 to 24, 2016 in Dabat Health and Demographic Surveillance System (HDSS) in northwest Ethiopia. The result was linked with verbal autopsy (VA) information completed for each of the deaths as part of the ongoing HDSS. The SA tool was adapted from INDEPTH Network. Three delay model approach was used to classify the delay types that contributed for the deaths investigated. Descriptive statistics was used to analyze the data.SA was completed for 37 (94.9%) of the 39 neonatal deaths

2017 BMC Pediatrics

20. Sex differences in microRNA-mRNA networks: examination of novel epigenetic programming mechanisms in the sexually dimorphic neonatal hypothalamus Full Text available with Trip Pro

Sex differences in microRNA-mRNA networks: examination of novel epigenetic programming mechanisms in the sexually dimorphic neonatal hypothalamus Sexual differentiation of the male brain, and specifically the stress circuitry in the hypothalamus, is primarily driven by estrogen exposure during the perinatal period. Surprisingly, this single hormone promotes diverse programs of sex-specific development that vary widely between different cell types and across the developing male brain (...) on the miRNA environment as a whole. Then, we utilized traditional hypothesis testing to identify individual miRNA with significantly sex-biased expression. Finally, we performed a transcriptome-wide mapping of Argonaute footprints by high-throughput sequencing of RNA isolated by cross-linking immunoprecipitation (Ago HITS-CLIP) to empirically characterize targeting relationship between estrogen-responsive miRNAs and their messenger RNA (mRNA) targets.In this study, we demonstrated that the neonatal

2017 Biology of sex differences

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