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Neurotransmitter Physiology

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101. Exercise Physiology (Treatment)

Exercise Physiology (Treatment) Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODg0ODQtb3ZlcnZpZXc= processing > Exercise (...) Physiology Updated: Oct 20, 2015 Author: Amer Suleman, MD; Chief Editor: Craig C Young, MD Share Email Print Feedback Close Sections Sections Exercise Physiology Overview Overview Exercise represents one the highest levels of extreme stresses to which the body can be exposed. For example, in a person who has an extremely high fever approaching the level of lethality, the body metabolism increases to approximately 100% above normal; by comparison, the metabolism of the body during a marathon race

2014 eMedicine.com

102. Normal Sleep, Sleep Physiology, and Sleep Deprivation: General Principles (Treatment)

Normal Sleep, Sleep Physiology, and Sleep Deprivation: General Principles (Treatment) Normal Sleep, Sleep Physiology, and Sleep Deprivation: Normal Sleep in Adults, Infants, and the Elderly, Sleep Physiology, Circadian Rhythms That Influence Sleep Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method (...) =getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE4ODIyNi1vdmVydmlldw== processing > Normal Sleep, Sleep Physiology, and Sleep Deprivation Updated: Dec 03, 2015 Author: M Suzanne Stevens, MD, MS, D-ABSM; Chief Editor: Selim R Benbadis, MD Share Email Print Feedback Close Sections Sections Normal Sleep, Sleep Physiology, and Sleep Deprivation Normal Sleep in Adults, Infants, and the Elderly Normal sleep is divided into non–rapid eye movement (NREM) and rapid eye movement (REM

2014 eMedicine.com

103. Normal Sleep, Sleep Physiology, and Sleep Deprivation: General Principles (Follow-up)

Normal Sleep, Sleep Physiology, and Sleep Deprivation: General Principles (Follow-up) Normal Sleep, Sleep Physiology, and Sleep Deprivation: Normal Sleep in Adults, Infants, and the Elderly, Sleep Physiology, Circadian Rhythms That Influence Sleep Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method (...) =getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE4ODIyNi1vdmVydmlldw== processing > Normal Sleep, Sleep Physiology, and Sleep Deprivation Updated: Dec 03, 2015 Author: M Suzanne Stevens, MD, MS, D-ABSM; Chief Editor: Selim R Benbadis, MD Share Email Print Feedback Close Sections Sections Normal Sleep, Sleep Physiology, and Sleep Deprivation Normal Sleep in Adults, Infants, and the Elderly Normal sleep is divided into non–rapid eye movement (NREM) and rapid eye movement (REM

2014 eMedicine.com

104. Exercise Physiology (Follow-up)

Exercise Physiology (Follow-up) Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODg0ODQtb3ZlcnZpZXc= processing > Exercise (...) Physiology Updated: Oct 20, 2015 Author: Amer Suleman, MD; Chief Editor: Craig C Young, MD Share Email Print Feedback Close Sections Sections Exercise Physiology Overview Overview Exercise represents one the highest levels of extreme stresses to which the body can be exposed. For example, in a person who has an extremely high fever approaching the level of lethality, the body metabolism increases to approximately 100% above normal; by comparison, the metabolism of the body during a marathon race

2014 eMedicine.com

105. Exercise Physiology (Diagnosis)

Exercise Physiology (Diagnosis) Exercise Physiology: Overview, Basic Concepts -- Sex Differences, Musculoskeletal System Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODg0ODQtb3ZlcnZpZXc= processing > Exercise (...) Physiology Updated: Oct 20, 2015 Author: Amer Suleman, MD; Chief Editor: Craig C Young, MD Share Email Print Feedback Close Sections Sections Exercise Physiology Overview Overview Exercise represents one the highest levels of extreme stresses to which the body can be exposed. For example, in a person who has an extremely high fever approaching the level of lethality, the body metabolism increases to approximately 100% above normal; by comparison, the metabolism of the body during a marathon race

2014 eMedicine.com

106. State-dependent and reflex drives to the upper airway: basic physiology with clinical implications (Full text)

State-dependent and reflex drives to the upper airway: basic physiology with clinical implications The root cause of the most common and serious of the sleep disorders is impairment of breathing, and a number of factors predispose a particular individual to hypoventilation during sleep. In turn, obstructive hypopneas and apneas are the most common of the sleep-related respiratory problems and are caused by dysfunction of the upper airway as a conduit for airflow. The overarching principle (...) sleep; 2) convergence of diverse neurotransmitters and signaling pathways onto one root mechanism that may explain pharyngeal motor suppression in sleep and drug-induced brain sedation; 3) the lateral reticular formation as a key hub of respiratory and reflex drives to the upper airway.

2013 Journal of Applied Physiology PubMed abstract

107. Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study

Hallucinogens Physiological Effects of Drugs Psychotropic Drugs Serotonin Antagonists Serotonin Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Serotonin Receptor Agonists (...) Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove

2013 Clinical Trials

108. The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes

Schizophrenia Marijuana Abuse Schizophrenia Spectrum and Other Psychotic Disorders Mental Disorders Substance-Related Disorders Chemically-Induced Disorders Dronabinol Hallucinogens Physiological Effects of Drugs Psychotropic Drugs Analgesics, Non-Narcotic Analgesics Sensory System Agents Peripheral Nervous System Agents Cannabinoid Receptor Agonists Cannabinoid Receptor Modulators Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Hormones Hormones, Hormone Substitutes, and Hormone (...) The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2013 Clinical Trials

109. Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School

Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect of Tyrosine on Behavioral, Physiological and Nutritional Status During Survive, Evade, Resist, Escape (SERE) School The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01823276 Recruitment Status : Completed

2013 Clinical Trials

110. Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. (Full text)

Central Regulation of Pituitary-Thyroid Axis Under Physiological and Pathophysiological Conditions. TRH is a tripeptide amide that functions as a neurotransmitter but also serves as a neurohormone that has a critical role in the central regulation of the hypothalamic-pituitary-thyroid axis. Hypophysiotropic TRH neurons involved in this neuroendocrine process are located in the hypothalamic paraventricular nucleus and secrete TRH into the pericapillary space of the external zone of the median (...) to the regulation of hypophysiotropic TRH neurons under physiological and pathophysiological conditions.

2013 Endocrine Reviews PubMed abstract

111. Dopamine in human follicular fluid is associated with cellular uptake and metabolism-dependent generation of reactive oxygen species in granulosa cells: implications for physiology and pathology. (Full text)

Dopamine in human follicular fluid is associated with cellular uptake and metabolism-dependent generation of reactive oxygen species in granulosa cells: implications for physiology and pathology. Is the neurotransmitter dopamine (DA) in the human ovary involved in the generation of reactive oxygen species (ROS)?Human ovarian follicular fluid contains DA, which causes the generation of ROS in cultured human granulosa cells (GCs), and alterations of DA levels in follicular fluid and DA uptake (...) /metabolism in GCs in patients with polycystic ovary syndrome (PCOS) are linked to increased levels of ROS.DA is an important neurotransmitter in the brain, and the metabolism of DA results in the generation of ROS. DA was detected in human ovarian homogenates, but whether it is present in follicular fluid and plays a role in the follicle is not known.We used human follicular fluid from patients undergoing in vitro fertilization (IVF), GCs from patients with or without PCOS and also employed mathematical

2013 Human Reproduction PubMed abstract

112. Molecular bases of circadian rhythmicity in renal physiology and pathology. (Full text)

sensitivity, physical activity, vascular tone, autonomic function and neurotransmitter release from sympathetic innervations. The circadian rhythmicity of body physiology is driven by central and peripheral biological clockworks and entrained by the geophysical light/dark cycle. Chronodisruption, defined as the mismatch between environmental-social cues and physiological-behavioral patterns, causes internal desynchronization of periodic functions, leading to pathophysiological mechanisms underlying (...) Molecular bases of circadian rhythmicity in renal physiology and pathology. The physiological processes that maintain body homeostasis oscillate during the day. Diurnal changes characterize kidney functions, comprising regulation of hydro-electrolytic and acid-base balance, reabsorption of small solutes and hormone production. Renal physiology is characterized by 24-h periodicity and contributes to circadian variability of blood pressure levels, related as well to nychthemeral changes of sodium

2013 Transplantation PubMed abstract

113. Midazolam Whole Body Physiologically Based Pharmacokinetic Model

Midazolam Whole Body Physiologically Based Pharmacokinetic Model Midazolam Whole Body Physiologically Based Pharmacokinetic Model - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Midazolam Whole Body (...) Physiologically Based Pharmacokinetic Model (MidPBPK) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01973894 Recruitment Status : Completed First Posted : November 1, 2013 Last Update Posted : May 25, 2017 Sponsor: Università degli Studi dell'Insubria Collaborator: University of Milan Information provided

2012 Clinical Trials

114. The physiological role of taurine. (Full text)

The physiological role of taurine. 4399554 1972 02 17 2018 11 30 0264-6021 123 4 1971 Jul The Biochemical journal Biochem. J. The physiological role of taurine. 45P-46P Kaczmarek L K LK Davison A N AN eng Journal Article England Biochem J 2984726R 0264-6021 0 Neurotransmitter Agents 1EQV5MLY3D Taurine IM Animals Cerebral Cortex metabolism Electric Stimulation Extracellular Space In Vitro Techniques Neurotransmitter Agents metabolism Rats Synaptic Membranes physiology Taurine metabolism (...) physiology 1971 7 1 1971 7 1 0 1 1971 7 1 0 0 ppublish 4399554 PMC1177059 Pharmacol Rev. 1965 Dec;17(4):347-91 5321711 J Neurochem. 1968 Oct;15(10):1141-9 5711127 J Neurochem. 1969 Aug;16(8):1235-44 5803799 Biochem J. 1971 May;122(5):759-63 5129271 Biochim Biophys Acta. 1956 Jan;19(1):66-73 13304071

1971 Biochemical Journal PubMed abstract

115. A Physiological Mechanism for Hebb's Postulate of Learning (Full text)

A Physiological Mechanism for Hebb's Postulate of Learning Hebb's postulate of learning envisages that activation or inactivation of extant synaptic contacts in plastic neural networks depends on the synchronous impulse activity of pre- and postsynaptic nerve cells. The physiological mechanism proposed here for this process posits that at synapses acting according to Hebb's postulate, the receptors for the neurotransmitter are eliminated from the postsynaptic membrane by the transient reversals (...) of the sign of membrane polarization that occur during action potential impulses in the postsynaptic cell. But, since the release of neurotransmitter drives the membrane potential of the synaptic zone towards a level about half-way between the negative-inside resting potential and the positive-inside action potential, it would follow that the membrane patches surrounding the receptors of a synapse whose activity has contributed to setting off the postsynaptic impulse would be spared the full extent

1973 Proceedings of the National Academy of Sciences of the United States of America PubMed abstract

116. Specificity of the Antibody Receptor Site to D-Lysergamide: Model of a Physiological Receptor for Lysergic Acid Diethylamide (Full text)

Specificity of the Antibody Receptor Site to D-Lysergamide: Model of a Physiological Receptor for Lysergic Acid Diethylamide Antibodies to D-lysergic acid have been produced in rabbits and guinea pigs and a radioimmunoassay for the hapten was developed. The specificity of this lysergamide-antilysergamide reaction was determined by competitive binding with unlabeled lysergic acid diethylamide (LSD), psychotomimetic drugs, neurotransmitters, and other compounds with diverse structures. LSD

1971 Proceedings of the National Academy of Sciences of the United States of America PubMed abstract

117. Evidence against a physiological role of prostaglandins in the regulation of noradrenaline release in the cat spleen. (Full text)

not play an important physiological role in the regulation of adrenergic neurotransmission in the cat spleen. In this tissue the major endogenous negative feed-back regulatory mechanism is triggered by the neurotransmitter through the activation of prejunctional alpha-adrenoceptors. (...) Evidence against a physiological role of prostaglandins in the regulation of noradrenaline release in the cat spleen. 1. The effects of prostaglandins E2 (PGE2) and indomethacin on responses and on noradrenaline overflow elicited by nerve stimulation were studied in the perfused cat's spleen, at different calcium concentrations in the perfusion medium: 0-26, 0-65 and 2-6 mve stimulation and in the overflow of the transmitter. PGE2 was more effective in reducing transmitter overflow at 5 than

1975 The Journal of physiology PubMed abstract

118. Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications. (Full text)

nervous effects known to be mediated via non-adrenergic, non-cholinergic nerve fibres were accompanied by significant increases of the VIP concentration in the venous effluent. The possible physiological implications of these findings are discussed and it is proposed that VIP may be a neurotransmitter in the gastrointestinal tract. (...) Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications. 1. The release of vasoactive intestinal polypeptide (VIP) into blood from the gastrointestinal tract was studied when eliciting autonomic nervous effects known to be mediated via non-adrenergic, non-cholinergic nerve fibres. All studies were performed on animals given atropine. 2. Electrical stimulation of the low threshold vagal fibres to the stomach did

1978 The Journal of physiology PubMed abstract

119. Effects of Vortioxetine (Lu AA21004) on the Concentrations of Selected Neurotransmitters in Healthy Male Adults

Posted: December 13, 2013 Last Update Posted: December 13, 2013 Last Verified: October 2013 Keywords provided by Takeda: Drug Therapy pharmacodynamic Additional relevant MeSH terms: Layout table for MeSH terms Vortioxetine Neurotransmitter Agents Antidepressive Agents Psychotropic Drugs Anti-Anxiety Agents Tranquilizing Agents Central Nervous System Depressants Physiological Effects of Drugs Serotonin Uptake Inhibitors Neurotransmitter Uptake Inhibitors Membrane Transport Modulators Molecular (...) Effects of Vortioxetine (Lu AA21004) on the Concentrations of Selected Neurotransmitters in Healthy Male Adults Effects of Vortioxetine (Lu AA21004) on the Concentrations of Selected Neurotransmitters in Healthy Male Adults - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2011 Clinical Trials

120. Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders

levels occur in PKU patients who are treated with Kuvan therapy, and that beneficial changes in cognition, especially executive functioning skills as measured by validated measurement questionnaires may result. Secondary Outcome Measures : change in neurotransmitter synthesis [ Time Frame: assessment during a 4 week trial of Kuvan administration ] This study seeks to establish evidence: that physiologic changes, unrelated to effect on the PAH enzyme, occur in PKU patients who are treated with Kuvan® (...) Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved

2011 Clinical Trials

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