How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

21,772 results for

Neurotransmitter Physiology

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

21761. Protein-protein interactions and protein modules in the control of neurotransmitter release. (PubMed)

the spatial and temporal regulation of the exocytotic machinery. The majority of these interactions are mediated by specific protein modules and domains that are found in many proteins and are involved in numerous intracellular processes. In this paper, the possible physiological role of these multiple protein-protein interactions is analysed, with ensuing updating and clarification of the present molecular model of the process of neurotransmitter release. (...) Protein-protein interactions and protein modules in the control of neurotransmitter release. Information transfer among neurons is operated by neurotransmitters stored in synaptic vesicles and released to the extracellular space by an efficient process of regulated exocytosis. Synaptic vesicles are organized into two distinct functional pools, a large reserve pool in which vesicles are restrained by the actin-based cytoskeleton, and a quantitatively smaller releasable pool in which vesicles

Full Text available with Trip Pro

1999 Philosophical Transactions of the Royal Society B: Biological Sciences

21762. Neurotransmitter Receptors in Fetal Tissue Transplants: Expression and Functional Significance (PubMed)

, display a patchy distribution which is dissimilar to that in the corresponding adult host tissue. This manuscript discusses this "abnormal" receptor distribution and possible explanations. Electrophysiological studies have indicated that some of the transplant receptors respond to physiological and pharmacological stimulation, suggesting that they are functional. However, the association of receptor expression with behavioral recovery is uncertain. The expression of neurotransmitter receptors (...) Neurotransmitter Receptors in Fetal Tissue Transplants: Expression and Functional Significance Numerous studies have examined receptor expression in neural transplants and their possible role in transplant-induced functional recovery from lesion-induced deficits. Herein we attempt to summarize the results of these studies, especially those from studies involving striatal transplants. Autoradiographic studies indicate that dopamine D1 and D2, muscarinic, cholinergic, 5-HT2, opiate mu, beta

Full Text available with Trip Pro

1993 Journal of neural transplantation & plasticity

21763. Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin. (PubMed)

Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin. The neurotransmitter serotonin plays a modulatory role in the regulation of various cognitive and behavioral functions such as sleep, mood, pain, depression, anxiety, and learning by binding to a number of serotonin receptors present upon the cell surface. The spectroscopic properties of serotonin and their modulation with ionization state have been studied. Results show that serotonin fluorescence (...) in nonpolar media has been studied. No significant binding or partitioning of serotonin to membranes under physiological conditions was observed. Serotonin fluorescence in solvents of lower polarity is characterized by an enhancement in intensity and a blue shift in emission maximum, although the solvatochromism is much less pronounced than in tryptophan. In view of the multiple roles played by the serotonergic systems in the central and peripheral nervous systems, these results are relevant to future

Full Text available with Trip Pro

1996 Biophysical journal

21764. To muster a cluster: Anchoring neurotransmitter receptors at synapses (PubMed)

To muster a cluster: Anchoring neurotransmitter receptors at synapses 9520364 1998 05 01 2018 11 13 0027-8424 95 7 1998 Mar 31 Proceedings of the National Academy of Sciences of the United States of America Proc. Natl. Acad. Sci. U.S.A. To muster a cluster: anchoring neurotransmitter receptors at synapses. 3341-3 Colledge M M Department of Physiology, University of North Carolina, Chapel Hill, NC 27599-7545, USA. Froehner S C SC eng Journal Article United States Proc Natl Acad Sci U S A 7505876 (...) 0027-8424 0 Muscle Proteins 0 Receptors, Neurotransmitter 0 Receptors, Nicotinic 0 peripheral membrane protein 43K IM Animals Humans Muscle Proteins chemistry physiology Neuromuscular Junction physiology Receptors, Neurotransmitter physiology Receptors, Nicotinic chemistry physiology Synapses physiology Synaptic Transmission physiology 1998 5 9 1998 5 9 0 1 1998 5 9 0 0 ppublish 9520364 PMC33847 Proc Natl Acad Sci U S A. 1974 Apr;71(4):1376-8 4524643 Nature. 1997 Jan 30;385(6615):439-42 9009191 J

Full Text available with Trip Pro

1998 Proceedings of the National Academy of Sciences of the United States of America

21765. Recent aspects of gonadal hormone and neurotransmitter interactions with synovial and immune cells: implications in rheumatoid arthritis (PubMed)

@unige.it Straub R H RH eng Journal Article Review England Ann Rheum Dis 0372355 0003-4967 0 Gonadal Steroid Hormones 0 Neurotransmitter Agents IM Arthritis, Rheumatoid immunology physiopathology Autoimmune Diseases immunology physiopathology Gonadal Steroid Hormones physiology Humans Immunity, Cellular Neurotransmitter Agents physiology Synovial Membrane physiopathology 69 2000 9 8 11 0 2000 10 7 11 1 2000 9 8 11 0 ppublish 10976076 PMC1753272 Clin Exp Rheumatol. 1993 Nov-Dec;11(6):597-601 8299250 J (...) Recent aspects of gonadal hormone and neurotransmitter interactions with synovial and immune cells: implications in rheumatoid arthritis 10976076 2000 10 04 2018 11 13 0003-4967 59 9 2000 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. Recent aspects of gonadal hormone and neurotransmitter interactions with synovial and immune cells: implications in rheumatoid arthritis. 657-61 Cutolo M M Division of Rheumatology Department of Internal Medicine University of Genova, Genova, Italy. mcutolo

Full Text available with Trip Pro

2000 Annals of the Rheumatic Diseases

21766. Can the Ca2+ hypothesis and the Ca2+-voltage hypothesis for neurotransmitter release be reconciled? (PubMed)

Can the Ca2+ hypothesis and the Ca2+-voltage hypothesis for neurotransmitter release be reconciled? It is well established that Ca2+ plays a key role in promoting the physiological depolarization-induced release (DIR) of neurotransmitters from nerve terminals (Ca2+ hypothesis). Yet, evidence has accumulated for the Ca2+-voltage hypothesis, which states that not only is Ca2+ required, but membrane potential as such also plays a pivotal role in promoting DIR. An essential aspect of the Ca2 (...) + concentration. Spontaneous release in turn is governed by a subset of the molecular scheme for DIR, under conditions of no depolarization. Prevailing estimates for the intracellular calcium concentration, [Ca2+]i, in physiological DIR rely on experiments under conditions of CIR. Our theory suggests that these estimates are too high, because depolarization is absent in these experiments and [Ca2+]i is held at high levels for an extended period.

Full Text available with Trip Pro

2002 Proceedings of the National Academy of Sciences of the United States of America

21767. Cooperative mechanisms of neurotransmitter action in central nervous sensitization (PubMed)

United States NS 09743 NS NINDS NIH HHS United States P01 NS011255 NS NINDS NIH HHS United States R21 AR048371 AR NIAMS NIH HHS United States NS 01145 NS NINDS NIH HHS United States Journal Article Research Support, U.S. Gov't, P.H.S. Review Netherlands Prog Brain Res 0376441 0079-6123 0 Neurotransmitter Agents S07O44R1ZM Capsaicin IM Animals Arthritis chemically induced Capsaicin Central Nervous System physiology Neurotransmitter Agents physiology Pain chemically induced physiopathology 72 1996 1 1 (...) Cooperative mechanisms of neurotransmitter action in central nervous sensitization 9000723 1997 03 11 2018 11 13 0079-6123 110 1996 Progress in brain research Prog. Brain Res. Cooperative mechanisms of neurotransmitter action in central nervous sensitization. 151-66 Willis W D WD Marine Biomedical Institute, Galveston, TX 77555-1069, USA. Sluka K A KA Rees H H Westlund K N KN eng NS 28064 NS NINDS NIH HHS United States R21 AR048371-02 AR NIAMS NIH HHS United States R01 NS009743 NS NINDS NIH HHS

Full Text available with Trip Pro

1996 Progress in Brain Research

21768. McGill investigators examining possible links between diet, brain neurotransmitters and behaviour. (PubMed)

McGill investigators examining possible links between diet, brain neurotransmitters and behaviour. 6132678 1983 06 10 2008 11 20 0008-4409 128 9 1983 May 01 Canadian Medical Association journal Can Med Assoc J McGill investigators examining possible links between diet, brain neurotransmitters and behaviour. 1058-9 Welsh J E JE eng News Canada Can Med Assoc J 0414110 0008-4409 0 Neurotransmitter Agents AIM IM Brain physiology Diet Humans Mental Disorders physiopathology Neurotransmitter Agents (...) physiology 1983 5 1 1983 5 1 0 1 1983 5 1 0 0 ppublish 6132678 PMC1874878

Full Text available with Trip Pro

1983 Canadian Medical Association Journal

21769. Platelet-induced neurogenic coronary contractions due to accumulation of the false neurotransmitter, 5-hydroxytryptamine. (PubMed)

Platelet-induced neurogenic coronary contractions due to accumulation of the false neurotransmitter, 5-hydroxytryptamine. The purpose of this study was to determine if 5-hydroxytryptamine released from aggregating platelets could be accumulated and released by canine coronary adrenergic nerves, and if the false neurotransmitter resulted in an abnormal response of the smooth muscle to nerve stimulation. Isometric tension was measured in rings of epicardial coronary suspended in organ chambers (...) filled with physiological salt solution. The response to electrical stimulation or exogenously added norepinephrine was elicited after contraction with prostaglandin F2 alpha. Electrical stimulation and exogenous norepinephrine caused beta-adrenergic relaxation of control rings. However, after rings were exposed for 2 h to aggregating platelets or 5-hydroxytryptamine, electrical stimulation caused frequency-dependent contractions. These contractions were prevented by the serotonergic antagonists

Full Text available with Trip Pro

1985 Journal of Clinical Investigation

21770. Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters. (PubMed)

United States J Clin Invest 7802877 0021-9738 0 Calmodulin 0 Diglycerides 0 Hormones 0 Neurotransmitter Agents 0 Phosphatidylinositols 0 Receptors, Cell Surface EC 2.7.- Protein Kinases EC 2.7.11.13 Protein Kinase C SY7Q814VUP Calcium AIM IM Animals Calcium physiology Calmodulin physiology Diglycerides physiology Hormones physiology Humans Neurotransmitter Agents physiology Phosphatidylinositols physiology Protein Kinase C Protein Kinases physiology Receptors, Cell Surface physiology 59 1985 6 1 1985 (...) Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters. 2861213 1985 07 30 2018 11 13 0021-9738 75 6 1985 Jun The Journal of clinical investigation J. Clin. Invest. Role of calcium and phosphoinositides in the actions of certain hormones and neurotransmitters. 1753-7 Exton J H JH eng AM18660 AM NIADDK NIH HHS United States AM33291 AM NIADDK NIH HHS United States Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Full Text available with Trip Pro

1985 Journal of Clinical Investigation

21771. Neurotransmitter antagonism in management of irritable bowel syndrome. (PubMed)

Neurotransmitter antagonism in management of irritable bowel syndrome. 10744083 2000 04 11 2015 06 16 0140-6736 355 9209 2000 Mar 25 Lancet (London, England) Lancet Neurotransmitter antagonism in management of irritable bowel syndrome. 1030-1 Lembo T T Department of Medicine, Harvard Medical School Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. eng Clinical Trial Comment Journal Article Multicenter Study Randomized Controlled Trial England Lancet 2985213R 0140-6736 0 Carbolines 0 (...) Serotonin Antagonists 13Z9HTH115 alosetron 333DO1RDJY Serotonin AIM IM Lancet. 2000 Mar 25;355(9209):1035-40 10744088 Carbolines therapeutic use Colonic Diseases, Functional drug therapy physiopathology Humans Serotonin physiology Serotonin Antagonists therapeutic use 2000 4 1 9 0 2000 4 15 9 0 2000 4 1 9 0 ppublish 10744083 S0140-6736(00)02028-6 10.1016/S0140-6736(00)02028-6

2000 Lancet (London, England) Controlled trial quality: uncertain

21772. Ricardo Miledi and the foundations of synaptic and extra-synaptic neurotransmitter receptor physiology (PubMed)

Ricardo Miledi and the foundations of synaptic and extra-synaptic neurotransmitter receptor physiology 17446218 2007 08 09 2018 11 13 0022-3751 581 Pt 3 2007 Jun 15 The Journal of physiology J. Physiol. (Lond.) Ricardo Miledi and the foundations of synaptic and extra-synaptic neurotransmitter receptor physiology. 890-2 Eusebi Fabrizio F Dipartimento di Fisiologia Umana & Farmacologia, Centro di Eccellenza BEMM, Università di Roma Sapienza, Italy. fabrizio.eusebi@uniroma1.it eng Biography (...) Historical Article Journal Article 2007 04 19 England J Physiol 0266262 0022-3751 0 Neurotransmitter Agents 0 Receptors, Cholinergic N9YNS0M02X Acetylcholine IM Acetylcholine history metabolism Action Potentials Animals Electrophysiology history History, 20th Century Humans Muscle Denervation Muscle, Skeletal innervation Neuromuscular Junction metabolism Neurotransmitter Agents history metabolism Receptors, Cholinergic history metabolism Synaptic Transmission Time Factors Miledi Ricardo R 2007 4 21 9 0

Full Text available with Trip Pro

2007 The Journal of physiology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>