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68101. Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases

Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00001667 Recruitment Status : Completed First Posted : December 10, 2002 Last Update Posted : March 4, 2008 Sponsor: National Institute of Neurological

1999 Clinical Trials

68102. Neuropsychological Evaluation of Psychiatric and Neurological Patients

by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City. Study Design Go to Layout table for study information Study Type : Observational Enrollment : 4300 participants Official Title: Neuropsychological Evaluation of Psychiatric and Neurological Patients Study Start Date : October 18, 1983 Study Completion Date : December 20, 2006 Resource links (...) Neuropsychological Evaluation of Psychiatric and Neurological Patients Neuropsychological Evaluation of Psychiatric and Neurological Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

1999 Clinical Trials

68103. Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers

Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00001164 Recruitment Status : Completed First Posted : December 10, 2002 Last Update Posted : March 5

1999 Clinical Trials

68104. National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial

National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. National Institute of Neurological Disorders and Stroke (NINDS) Parkinson's Disease Neuroprotection Trial The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00063193 Recruitment Status : Completed First Posted : June 25, 2003 Last Update Posted

2003 Clinical Trials

68105. Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)

Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART) Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00054795 Recruitment Status : Completed First Posted : February 13, 2003 Last Update Posted : May 8, 2007 Sponsor: Pharmacyclics LLC. Information

2003 Clinical Trials

68106. Oregon Center for Complementary and Alternative Medicine in Neurological Disorders

Purpose: Treatment Official Title: Oregon Center for Complementary and Alternative Medicine in Neurological Disorders Study Start Date : September 1999 Study Completion Date : December 2004 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members (...) Oregon Center for Complementary and Alternative Medicine in Neurological Disorders Oregon Center for Complementary and Alternative Medicine in Neurological Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2001 Clinical Trials

68107. Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials

and will be administered one last time as part of the exit evaluation. Study Design Go to Layout table for study information Study Type : Observational Enrollment : 675 participants Observational Model: Natural History Official Title: Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from (...) Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials Neurodevelopmental and Neurological Study of Infants and Children With HIV-1 Infection and AIDS in Clinical Trials - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

1999 Clinical Trials

68108. Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1

. As an option, all patients may receive an additional 16 weeks of low-dose nimodipine. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Enrollment : 36 participants Masking: Double Primary Purpose: Treatment Official Title: Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 Actual Study Completion Date : June 1994 Resource links provided by the National Library of Medicine related topics: available (...) Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

1999 Clinical Trials

68109. Diagnosis and History Study of Patients With Different Neurological Conditions

Neurological Conditions Actual Study Start Date : August 30, 1993 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff (...) Diagnosis and History Study of Patients With Different Neurological Conditions Diagnosis and History Study of Patients With Different Neurological Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

1999 Clinical Trials

68110. Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders

and activation of cognitive, motor, and sensory functions. Study Design Go to Layout table for study information Study Type : Observational Enrollment : 830 participants Official Title: Structural and Functional Imaging of Neurologically Impaired Patients and Normal Volunteers With 1.5 and 3.0 Tesla MRI Study Start Date : December 1992 Study Completion Date : July 2003 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Eligibility (...) Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding

1999 Clinical Trials

68111. Genetic Aspects of Neurologic and Psychiatric Disorders

extraction or to establish a lymphoblast cell line to be used in genetic tests. Samples will also be collected from family members and controls for these studies. Study Design Go to Layout table for study information Study Type : Observational Enrollment : 1227 participants Official Title: Genetic Aspects of Neurologic and Psychiatric Disorders Study Start Date : April 1996 Study Completion Date : March 2004 Resource links provided by the National Library of Medicine related topics: related topics (...) Genetic Aspects of Neurologic and Psychiatric Disorders Genetic Aspects of Neurologic and Psychiatric Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Genetic Aspects of Neurologic and Psychiatric

1999 Clinical Trials

68112. Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy

Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record (...) Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal

1999 Clinical Trials

68113. A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease.

therapy. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 0 participants Intervention Model: Parallel Assignment Primary Purpose: Treatment Official Title: A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease. Resource links provided by the National Library of Medicine related topics: available for: resources: Arms and Interventions Go to Outcome Measures Go (...) A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease. A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached

1999 Clinical Trials

68114. Study of Inherited Neurological Disorders

Observational Model: Other Time Perspective: Other Official Title: Clinical and Molecular Manifestations of Inherited Neurological Disorders Study Start Date : February 8, 2000 Resource links provided by the National Library of Medicine related topics: resources: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : Genetic disease identification; deep phenotyping of rare genetic neurological disorders; training of fellows and students [ Time Frame: Outcome measures assessed at initial (...) Study of Inherited Neurological Disorders Study of Inherited Neurological Disorders - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Study of Inherited Neurological Disorders The safety and scientific

2000 Clinical Trials

68115. Presymptomatic testing for Huntington's disease: a world wide survey. The World Federation of Neurology Research Group on Huntington's Disease. Full Text available with Trip Pro

Presymptomatic testing for Huntington's disease: a world wide survey. The World Federation of Neurology Research Group on Huntington's Disease. World wide data on presymptomatic testing for Huntington's disease using closely linked DNA markers show that 1479 persons at risk received completed test results up to the end of 1991. Testing has been carried out in 19 countries, with at least 88 centres involved, and numbers have levelled off after a peak in 1990. Only 5% of those at risk have been

1993 Journal of Medical Genetics

68116. Forestry workers exposed to vibration: a neurological study. Full Text available with Trip Pro

Forestry workers exposed to vibration: a neurological study. Neurological findings were examined in 186 forestry workers with a mean exposure to chain saw vibration of 16.6 hours. The prevalence of active vibration induced white fingers was 5%, parethaesias of the hands 53%, and muscle weakness 13%. Clinical polyneuropathy was observed in 16 forestry workers in the hands (7.5%) which did not correlate with alcohol consumption. Seventy nine forestry workers of the total population were selected (...) for electromyographic examination. Generalised EMG based polyneuropathy in the hands was observed in only two of the 79 forestry workers (2.5%). The carpal tunnel syndrome was found in 20 of the 79 forestry workers (26%). Headache and vertigo were not linked with exposure to vibration in forestry and a significant part of the numbness reported may be due to the carpal tunnel syndrome. Sensorimotor polyneuropathy is rare among forestry workers. The rise in the vibration detection thresholds was linked to the carpal

1988 British Journal of Industrial Medicine

68117. Immunoassay of P2 protein in cerebrospinal fluid in neurological disorders. Full Text available with Trip Pro

Immunoassay of P2 protein in cerebrospinal fluid in neurological disorders. Cerebrospinal fluid samples were obtained at lumbar puncture from 53 patients with a wide variety of neurological disorders. Cerebrospinal fluid samples were tested for the presence of P2 protein, a constituent of myelin, with an enzyme linked immunosorbent assay technique using a specific polyclonal antibody. High concentrations of P2 in the cerebrospinal fluid paralleled a raised IgG index (clearance ratio

1991 Journal of Clinical Pathology

68118. Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice. Full Text available with Trip Pro

Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice. Previously we described activating mutations of hbetac, the common signaling subunit of the receptors for the hematopoietic and inflammatory cytokines, GM-CSF, IL-3, and IL-5. The activated mutant, hbetacFIDelta, is able to confer growth factor-independent proliferation on the murine myeloid cell line FDC-P1, and on primary committed (...) myeloid progenitors. We have used this activating mutation to study the effects of chronic cytokine receptor stimulation. Transgenic mice were produced carrying the hbetacFIDelta cDNA linked to the constitutive promoter derived from the phosphoglycerate kinase gene, PGK-1. Transgene expression was demonstrated in several tissues and functional activity of the mutant receptor was confirmed in hematopoietic tissues by the presence of granulocyte macrophage and macrophage colony-forming cells (CFU-GM

1998 Journal of Clinical Investigation

68119. A New Neurological Syndrome with Mental Retardation, Choreoathetosis, and Abnormal Behavior Maps to Chromosome Xp11 Full Text available with Trip Pro

A New Neurological Syndrome with Mental Retardation, Choreoathetosis, and Abnormal Behavior Maps to Chromosome Xp11 Choreoathetosis is a major clinical feature in only a small number of hereditary neurological disorders. We define a new X-linked syndrome with a unique clinical picture characterized by mild mental retardation, choreoathetosis, and abnormal behavior. We mapped the disease in a four-generation pedigree to chromosome Xp11 by linkage analysis and defined a candidate region

1999 American Journal of Human Genetics

68120. Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. Full Text available with Trip Pro

Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. Amphiphysin I is a 128 kD protein highly concentrated in nerve terminals, where it has a putative role in endocytosis. It is a dominant autoantigen in patients with stiff-man syndrome associated with breast cancer, as well as in other paraneoplastic autoimmune neurological disorders. To elucidate the connection between amphiphysin I autoimmunity and cancer, we investigated its expression (...) isoform which represents an alternatively spliced variant of neuronal amphiphysin I missing a 42 amino acid insert. Our study suggests a link between amphiphysin I expression in cancer and amphiphysin I autoimmunity. The enhanced expression of amphiphysin I in some forms of cancer supports the hypothesis that amphiphysin family members may play a role in the biology of cancer cells.

1998 Molecular Medicine

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