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1. Individual differences in social network size linked to nucleus accumbens and hippocampal volumes in functional neurological disorder: A pilot study. (PubMed)

Individual differences in social network size linked to nucleus accumbens and hippocampal volumes in functional neurological disorder: A pilot study. In the biopsychosocial formulation of functional neurological (conversion) disorder (FND), little is known about relationships between social behavior and brain anatomy. We hypothesized that social behavior would relate to brain areas implicated in affiliative behaviors and that social network size would correlate with symptom severity (...) -epileptic seizure diagnosis; social network size inversely related to lifetime trauma burden, post-traumatic stress disorder severity and age.Only patient-reported scales were used and social network size information was not collected for healthy subjects.This neuroimaging pilot adds to the literature linking affiliation network brain areas to pro-social behaviors and enhances the biopsychosocial conceptualization of FND.Copyright © 2019 Elsevier B.V. All rights reserved.

2019 Journal of Affective Disorders

2. Suspected neurological conditions: recognition and referral

Suspected neurological conditions: recognition and referral Suspected neurological conditions: Suspected neurological conditions: recognition and referr recognition and referral al NICE guideline Published: 1 May 2019 www.nice.org.uk/guidance/ng127 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived (...) be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Suspected neurological conditions: recognition and referral (NG127) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

3. The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers (PubMed)

The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the FMR1 Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers The fragile X premutation (PM) allele contains a CGG expansion of 55-200 repeats in the FMR1 gene's promoter. Male PM carriers have an elevated risk of developing neurological and psychiatric changes, including an approximately 50% risk of the fragile X-associated tremor/ataxia syndrome

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2018 Frontiers in genetics

4. Central autoimmune channelopathies: a link between Neurology and Psychiatry

Central autoimmune channelopathies: a link between Neurology and Psychiatry Central autoimmune channelopathies: a link between Neurology and Psychiatry | JNNP blog by Since the recognition of antibodies against voltage – gated potassium channel (VGKC) and their pathogenic implication in central nervous system disorders (such as limbic encephalitis) in 2001, critical immunological and neurological advances have been achieved during the last 15 years. One of the main discoveries has been (...) that these VGKC antibodies usually target proteins outside of the channel protein, which are part of the VGKC complex (e.g. contactin-associated protein 2). Moreover, each specific antibody is associated with distinct clinical phenotypes, which commonly overlap. Clinically the primary neurological syndrome associated with VGKC antibodies is limbic encephalitis, classically presenting with severe memory impairment and secondary hippocampal atrophy. However, recently emerging psychiatric syndromes have been

2016 JNNP blog

5. Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder. (PubMed)

Corticolimbic structural alterations linked to health status and trait anxiety in functional neurological disorder. Affective symptoms influence health status (health-related quality of life) in functional neurological disorder (FND), and the salience network is implicated in the pathophysiology of FND and mood/anxiety disorders. We hypothesised that self-reported health status and affective symptoms would map onto salience network regions and that patients with FND would show decreased insular (...) limitations due to emotional problems, was independent of sensorimotor functional neurological symptom severity and motor FND subtype. In secondary within-group analyses, increased periaqueductal grey volume was associated with role limitations due to emotional problems. Impaired physical functioning correlated with decreased left anterior insular volumes.These findings support roles for several regions of the salience network in the pathophysiology of FND.© Article author(s) (or their employer(s) unless

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2017 Neurosurgery and Psychiatry

6. Neurological Manifestations of X-Linked Ichthyosis: Case Report and Review of the Literature (PubMed)

Neurological Manifestations of X-Linked Ichthyosis: Case Report and Review of the Literature A 5-year-old boy presented with mild autism and attention-deficit hyperactivity disorder (ADHD). Chromosomal microarray demonstrated a 1.7 Mb deletion at Xp22.31, which was consistent with X-linked ichthyosis (XLI). Further exam revealed dry, scaly skin on his abdomen and pretibial areas. Patients with mutations involving solely the STS gene or the recurrent ~2 Mb deletion may present with ADHD, whereas (...) those with larger deletions including the NLGN4 gene can present with both ADHD and autism. However, our patient presented with mild autism in addition to ADHD despite having only the recurrent deletion without loss of NLGN4. Such neurological manifestations of XLI warrant attention as practical targets of clinical management.

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2017 Case Reports in Genetics

7. Emerging Evidence for a Direct Link between EAAT-Associated Anion Channels and Neurological Disorders (PubMed)

Emerging Evidence for a Direct Link between EAAT-Associated Anion Channels and Neurological Disorders 28077704 2018 05 28 2018 12 02 1529-2401 37 2 2017 01 11 The Journal of neuroscience : the official journal of the Society for Neuroscience J. Neurosci. Emerging Evidence for a Direct Link between EAAT-Associated Anion Channels and Neurological Disorders. 241-243 10.1523/JNEUROSCI.2947-16.2017 Gonzalez-Suarez Aneysis D AD 0000-0003-3745-763X Yale University School of Medicine, Interdepartmental (...) ;9(11):1388-96 17041592 Prog Neurobiol. 2001 Sep;65(1):1-105 11369436 PLoS One. 2012;7(4):e35373 22506078 Cell. 2015 Jan 29;160(3):542-53 25635461 Curr Opin Neurobiol. 1999 Jun;9(3):293-8 10395570 J Biol Chem. 2015 Sep 18;290(38):22977-90 26203187 Glia. 2011 Feb;59(2):320-32 21125654 Curr Mol Pharmacol. 2013 Jul;6(2):66-73 23876150 Neurology. 2005 Aug 23;65(4):529-34 16116111 Neurochem Int. 2016 Sep;98:56-71 27013346 Brain. 2012 Nov;135(Pt 11):3416-25 23107647 J Neurosci. 2010 Oct 27;30(43):14446

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2017 The Journal of Neuroscience

8. X-linked adult-onset adrenoleukodystrophy: Psychiatric and neurological manifestations (PubMed)

X-linked adult-onset adrenoleukodystrophy: Psychiatric and neurological manifestations Adult-onset adrenoleukodystrophy is a rare x-linked inborn error of metabolism occurring predominantly in males with onset in early 30s. Here, we report a 34-year-old male with first signs of disease in early 20s manifesting as a pure psychiatric disorder. Prior to onset of neurological symptoms, this patient demonstrated a schizophrenia and bipolar-like presentation. The disease progressed over the next 10 (...) -13 years and his memory and motor problems became evident around the age of 33 years. Subsequently, diagnostic testing showed the typical magnetic resonance imaging and lab findings for adult-onset adrenoleukodystrophy. This case highlights adult-onset adrenoleukodystrophy which may present as a pure psychiatric disturbance in early adulthood and briefly discusses the prolonged time between the onset of psychiatric symptoms and the onset of neurological disease.

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2017 SAGE Open Medical Case Reports

9. The Combined Use of Ultrasound and Fetal Magnetic Resonance Imaging for a Comprehensive Fetal Neurological Assessment in Fetal Congenital Cardiac Defects

The Combined Use of Ultrasound and Fetal Magnetic Resonance Imaging for a Comprehensive Fetal Neurological Assessment in Fetal Congenital Cardiac Defects The Combined Use of Ultrasound and Fetal Magnetic Resonance Imaging for a Comprehensive Fetal Neurological Assessment in Fetal Congenital Cardiac Defects - Pasupathy - - BJOG: An International Journal of Obstetrics & Gynaecology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our (...) . Search within Search term Search term RCOG Scientific Impact Paper Free Access The Combined Use of Ultrasound and Fetal Magnetic Resonance Imaging for a Comprehensive Fetal Neurological Assessment in Fetal Congenital Cardiac Defects Scientific Impact Paper No. 60 Corresponding Author E-mail address: Correspondence : Royal College of Obstetricians and Gynaecologists, 27 Sussex Place, Regent's Park, London NW1 4RG. Email: Corresponding Author E-mail address: Correspondence : Royal College

2019 Royal College of Obstetricians and Gynaecologists

10. Neurology data and analysis: a guide for health professionals

the number and type of adult neurological outpatient appointments offered in England and how close they are made to the patient’s home. This information can help commissioners and clinicians assess whether they comply with recommendations by the Royal College of Physicians for scheduled outpatient care. Further information . to our monthly bulletin which gives a snapshot of our latest resources and key messages that we wish to share. Published 3 May 2017 Last updated 6 March 2019 6 March 2019 Added link (...) to neurology data catalogue. 27 February 2018 Added 'deaths associated with neurological conditions'. 3 May 2017 First published. Explore the topic Is this page useful? Thank you for your feedback Help us improve GOV.UK Don’t include personal or financial information like your National Insurance number or credit card details. What were you doing? What went wrong? Send Help us improve GOV.UK To help us improve GOV.UK, we’d like to know more about your visit today. We’ll send you a link to a feedback form

2019 Public Health England

11. European Academy of Neurology guideline on trigeminal neuralgia

European Academy of Neurology guideline on trigeminal neuralgia European Academy of Neurology guideline on trigeminal neuralgia - Bendtsen - - European Journal of Neurology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Ean Guidelines Free Access European Academy of Neurology guideline on trigeminal (...) neuralgia Corresponding Author E-mail address: Department of Neurology, Faculty of Health and Medical Sciences, Danish Headache Center, Rigshospitalet‐Glostrup, University of Copenhagen, Glostrup, Denmark Correspondence: L. Bendtsen, Danish Headache Center, Department of Neurology, Rigshospitalet‐Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, 2600 Glostrup, Denmark (tel.: +45 38633065; fax: +45 38633839; e‐mail: ). Pain Management Centre, National Hospital for Neurology

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2019 European Academy of Neurology

12. Global expression studies of schizophrenic brain: A Meta-analysis study linking neurological immune system with psychological disorders. (PubMed)

Global expression studies of schizophrenic brain: A Meta-analysis study linking neurological immune system with psychological disorders. Schizophrenia, a psychological disorder with enormous societal impact, is a result of abnormalities in gene expression and dysregulation of the immune response in the brain. Few studies have been conducted to understand its etiology, however, the exact molecular mechanism largely remains unknown, though some poorly understood theories abound. Present meta (...) -study links the role of central nervous system, immunological system and psychological disorders by using global expression approach and pathway analysis. We retrieved genome-wide mRNA expression data and clinico-pathological information from five independent studies of schizophrenic patients from Gene Expression Omnibus database. We continued further with three studies having common platform. Our result showed a total of 527 differentially expressed genes of which 314 are up regulated and 213

2016 CNS & neurological disorders drug targets

13. The link between anesthesiology and neurology: a mindful cooperation to improve brain protection. (PubMed)

The link between anesthesiology and neurology: a mindful cooperation to improve brain protection. Preventing neurological injury is mandatory during the perioperative period of any kind of surgery and in the care of critically ill patients in the intensive care unit. During daily practice, both anesthesiologists and neurologists focus on brain protection as an integral part of systemic homeostasis maintenance. This article highlights the intriguing overlap between anesthesiology and neurology (...) in clinical practice along with its potential implications for outcome. Moreover, it focuses on the importance of the complementary expertise of both specialists in maintaining cerebral homeostasis, with the aim of improving outcome. A review of available evidence on anesthesiology and neurology interplay in clinical practice along with its potential implications for outcome has been conducted. Clinical vigilance and the use of shared monitoring and diagnostic technology could allow early recognition

2016 Minerva anestesiologica

14. EFhd2, a Protein Linked to Alzheimer's Disease and Other Neurological Disorders (PubMed)

EFhd2, a Protein Linked to Alzheimer's Disease and Other Neurological Disorders EFhd2 is a conserved calcium binding protein linked to different neurological disorders and types of cancer. Although, EFhd2 is more abundant in neurons, it is also found in other cell types. The physiological function of this novel protein is still unclear, but it has been shown in vitro to play a role in calcium signaling, apoptosis, actin cytoskeleton, and regulation of synapse formation. Recently, EFhd2 (...) was shown to promote cell motility by modulating the activity of Rac1, Cdc42, and RhoA. Although, EFhd2's role in promoting cell invasion and metastasis is of great interest in cancer biology, this review focusses on the evidence that links EFhd2 to Alzheimer's disease (AD) and other neurological disorders. Altered expression of EFhd2 has been documented in AD, Parkinson's disease, Huntington's disease, Amyotrophic Lateral Sclerosis, and schizophrenia, indicating that Efhd2 gene expression is regulated

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2016 Frontiers in neuroscience

15. Neurology Links

Neurology Links Neurology Links Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Neurology Links Neurology Links Aka: Neurology Links (...) II. Resources: Anatomy and Education The Whole Brain Atlas Neurosurgery Teaching Files Human Brain Map MRI Slicer III. Resources: Organizations National Institute of Neurological Disorders American Academy of Neurology Alzheimer's Association Foundation of America National Foundation National Society Neurosurgery On-Call Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Neurology Links." Click on the image (or right click

2018 FP Notebook

16. Erratum to muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy (PubMed)

Erratum to muscle pathology, limb strength, walking gait, respiratory function and neurological impairment establish disease progression in the p.N155K canine model of X-linked myotubular myopathy [This corrects the article on p. 262 in vol. 3, PMID: 26605308.].

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2016 Annals of Translational Medicine

17. De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation (PubMed)

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation Disruptions to neuronal mRNA translation are hypothesized to underlie human neurodevelopmental syndromes. Notably, the mRNA translation re-initiation factor DENR is a regulator of eukaryotic translation and cell growth, but its mammalian functions are unknown. Here, we report that Denr influences the migration of murine cerebral cortical neurons in vivo (...) in different ways. Thus, our findings link human brain disorders to impaired mRNA translation re-initiation through perturbations in DENR (OMIM: 604550) function in neurons.Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

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2016 Cell reports

18. Survival and Health Care Use After Feeding Tube Placement in Children With Neurologic Impairment

Survival and Health Care Use After Feeding Tube Placement in Children With Neurologic Impairment Children with neurologic impairment (NI) often undergo feeding tube placement for undernutrition or aspiration. We evaluated survival and acute health care use after tube placement in this population.This is a population-based exposure-crossover study for which we use linked administrative data from Ontario, Canada. We identified children aged 13 months to 17 years with a diagnosis of NI undergoing

2019 EvidenceUpdates

19. Observational study: Compared to conventional CPR for in-hospital cardiac arrest, extracorporeal-CPR is associated with improved survival to hospital discharge and more favourable neurological outcome

Observational study: Compared to conventional CPR for in-hospital cardiac arrest, extracorporeal-CPR is associated with improved survival to hospital discharge and more favourable neurological outcome Compared to conventional CPR for in-hospital cardiac arrest, extracorporeal-CPR is associated with improved survival to hospital discharge and more favourable neurological outcome | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you (...) to conventional CPR for in-hospital cardiac arrest, extracorporeal-CPR is associated with improved survival to hospital discharge and more favourable neurological outcome Article Text Therapeutics/Prevention Observational study Compared to conventional CPR for in-hospital cardiac arrest, extracorporeal-CPR is associated with improved survival to hospital discharge and more favourable neurological outcome Lindsay Ryerson , Gonzalo Garcia Guerra , Laurance Lequier Statistics from Altmetric.com Commentary

2016 Evidence-Based Medicine (Requires free registration)

20. Community Water Fluoridation At the Levels Recommended By The U.S. Department of Health and Human Services Have Not Been Shown To Have An Effect On Children?s Neurological Development

of 5, and then assessed participants IQ at ages 7, 9, 11, 13, and then again at age 38. These findings show that CWF is safe in regards to neurological development, and it remains an effective and affordable way of reducing dental caries. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Broadbent/2015 1037 patients followed from age 3 to 38. Prospective Cohort Study Key results In children who lived (...) Community Water Fluoridation At the Levels Recommended By The U.S. Department of Health and Human Services Have Not Been Shown To Have An Effect On Children?s Neurological Development UTCAT3055, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Community Water Fluoridation At the Levels Recommended By The U.S. Department of Health and Human Services Have Not Been Shown To Have An Effect On Children’s Neurological

2016 UTHSCSA Dental School CAT Library

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