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Nerve Conduction Velocity

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141. Membrane properties and conduction velocity in sensory neurones following central or peripheral axotomy Full Text available with Trip Pro

Membrane properties and conduction velocity in sensory neurones following central or peripheral axotomy 1. The properties of dorsal root ganglion cells in the lumbosacral segments were examined with intracellular electrodes about 3 weeks after section of the central (dorsal roots) or peripheral processes in the cat.2. Chronic section of the peripheral nerve in the hind limb resulted in a reduction in conduction velocity of both the central and peripheral processes of sensory neurones.3. Sensory (...) neurones arising from the triceps surae and plantaris muscles were subject to ;disuse' conditions for about 3 weeks by section of the ventral roots combined with severance of the Achilles tendon. Under such conditions, the central and peripheral conduction velocities of these sensory neurones tended to decrease, but the decrease was significantly less than that following peripheral nerve section.4. Chronic section of the dorsal roots produced no significant changes in conduction velocity of the central

1977 The Journal of physiology

142. Electrophysiological study of the peripheral nervous system in children. Changes in proximal and distal conduction velocities from birth to age 5 years. Full Text available with Trip Pro

Electrophysiological study of the peripheral nervous system in children. Changes in proximal and distal conduction velocities from birth to age 5 years. Hoffman's reflex was evoked in the soleus muscle of 105 normal children from birth to age 5 years. This technique made it possible to determine conduction time and to estimate conduction velocity over the reflex arc. For 59 children, proprioceptive and motor distal nerve conduction velocities were calculated for the tibial nerve trunk (...) . These measurements enabled the common changes for these three velocities to be described in terms of an exponential curve. Proximal conduction velocity has similar values to those of proprioceptive distal nerve fibres: it is always higher than motor nerve conduction velocity, but the difference gradually diminishes, remaining constant after the eighteenth month. Conduction time diminishes between birth and one year of age, whereas height increases. Then conduction time increases slowly, reaching at about age 5

1979 Journal of neurology, neurosurgery, and psychiatry

143. Axonal conduction velocity and voluntary discharge properties of individual short toe extensor motor units in man. Full Text available with Trip Pro

Axonal conduction velocity and voluntary discharge properties of individual short toe extensor motor units in man. 1. The axonal conduction velocity and the voluntary discharge properties of 120 short toe extensor motor units were studied in man. 2. Electromyographic techniques were used which permitted the identification of individual motor unit potentials after proximal and distal electrical nerve stimulation and during maximum voluntary effort. 3. The necessary selectivity of the e.m.g (...) . recordings was achieved in two circumstances. In some subjects, previous motor nerve lesions distal to the point of stimulation had led to collateral sprouting with larger motor unit potentials. In other subjects an accessory deep peroneal nerve was present, so that lidocaine block of the main motor nerve left a small number of innervated motor units. 4. The axonal conduction velocities of the individual motor units ranged from 30 to 54 m/sec with most motor units between 35 and 45 m/sec. 5. Motor units

1978 The Journal of physiology

144. Electrophysiological aspects of sensory conduction velocity in healthy adults. 2. Ratio between the amplitude of sensory evoked potentials at the wrist on stimulating different fingers in both hands. Full Text available with Trip Pro

Electrophysiological aspects of sensory conduction velocity in healthy adults. 2. Ratio between the amplitude of sensory evoked potentials at the wrist on stimulating different fingers in both hands. The normal ratio between the amplitude of the sensory evoked potential (SEP) at the wrist on stimulating digits 1, 2, 3, and 5 was determined in 44 healthy adult subjects. The first digit had the larger amplitude, and the fifth digit the smallest SEP. The amplitude expresses the density of sensory (...) innervation in each finger. The ratio between the amplitude of different fingers varied according to the age of the subject. The amplitude of the SEP from a digit innervated by the median nerve decreased in the elderly more than the SEP amplitude of the digit innervated by the ulnar nerve, probably because of a chronic compression in the carpal tunnel. The changes in the normal amplitude ratio can be applied to the topographic diagnosis of radicular and brachial plexus lesions if a fixed segmental sensory

1978 Journal of neurology, neurosurgery, and psychiatry

145. Conduction velocity in proximal and distal portions of forelimb axons in the baboon Full Text available with Trip Pro

Conduction velocity in proximal and distal portions of forelimb axons in the baboon 1. Peripheral nerves of the baboon's forelimb were stimulated at different sites, and the latencies of antidromic action potentials were measured in intracellular records from forelimb motoneurones.2. The conduction velocity of single motor axons was slower in the brachial plexus than in the nerves of the arm and forearm. This proximal slowing of conduction velocity was more marked for rapidly conducting axons (...) than for the more slowly conducting ones.3. Gross recordings from dorsal and ventral roots showed that the conduction velocity was slower in the brachial plexus than in the arm for fast afferent as well as efferent nerve fibres.4. The proximal slowing of conduction velocity was shown to be due neither to errors of measurement nor to proximo-distal differences of temperature.

1968 The Journal of physiology

146. Nerve conduction, tactile sensibility, and the electromyogram after suture or compression of peripheral nerve: a longitudinal study in man. Full Text available with Trip Pro

Nerve conduction, tactile sensibility, and the electromyogram after suture or compression of peripheral nerve: a longitudinal study in man. In three patients sequential studies were performed of sensory and motor conduction after complete section and suture of the median nerve at the wrist and in one patient after partial section of the nerve. The sensory potential evoked by stimuli to digits III and I and recorded proximal to the suture line at the wrist appeared after a delay of three to four (...) years was three times faster than in adults. In the adults and in the children the maximum sensory conduction velocity was 10-25% of normal. It then increased at 3% per month during the first two years, and thereafter 10 times slower. Forty months after suture in the adults and 13-19 months after suture in the children the conduction velocity had reached 65-75% of normal. The pattern of discrete electrical activity during voluntary effort and the prolonged duration of motor unit potentials indicate

1979 Journal of neurology, neurosurgery, and psychiatry

147. NON-INVASIVE EVALUATION OF NERVE CONDUCTION IN SMALL DIAMETER FIBERS IN THE RAT Full Text available with Trip Pro

NON-INVASIVE EVALUATION OF NERVE CONDUCTION IN SMALL DIAMETER FIBERS IN THE RAT A novel non-invasive technique was applied to measure velocity within slow conducting axons in the distal extreme of the sciatic nerve (i.e., digital nerve) in a rat model. The technique is based on the extraction of rectified multiple unit activity (MUA) from in vivo whole nerve compound responses. This method reliably identifies compound action potentials in thinly myelinated fibers conducting at a range of 9-18 m (...) C-fiber response (ANOVA p<0.01). This technique offers a unique opportunity for the non-invasive, repeatable, and quantitative assessment of velocity in the subsets of Aδ and C fibers in parallel with evaluation of fast nerve conduction.

2013 Physiology journal

148. Transcutaneous Electrical Nerve Stimulation Improves Vascular Conductance After Coronary Artery Bypass Graft Surgery

Transcutaneous Electrical Nerve Stimulation Improves Vascular Conductance After Coronary Artery Bypass Graft Surgery Transcutaneous Electrical Nerve Stimulation Improves Vascular Conductance After Coronary Artery Bypass Graft Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Transcutaneous Electrical Nerve Stimulation Improves Vascular Conductance After Coronary Artery Bypass Graft Surgery (TEBCABG) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01777659 Recruitment Status : Completed First

2013 Clinical Trials

149. Second lumbrical and mixed nerve segmental conduction studies in carpal tunnel syndrome. (Abstract)

Second lumbrical and mixed nerve segmental conduction studies in carpal tunnel syndrome. We report the findings of 20 patients with carpal tunnel syndrome (CTS) who had segmental motor studies to the second lumbrical (2L) and mixed nerve action potential (MNAP) across the carpal tunnel.This was a prospective study of 20 patients randomly selected who had clinical and electrophysiologic evidence of CTS using standard techniques. Six CTS patients had studies pre- and post-surgical release.Mean 2L (...) motor amplitude reduction across the carpal tunnel was 55.19% ± 6.6% in patients (controls = 15.9% ± 9.4%). Mean motor velocity across the carpal tunnel was 23.4 ± 7.05 m/s versus 46.45 ± 6 m/s in controls. Mean reduction of the MNAP amplitudes was 79.0% ± 23% versus 20% ± 15% in controls. The mean MNAP velocity was 12.3 ± 13.1 m/s versus 48.35 ± 5.18 m/s in controls. The 6 surgical cases showed improvement in amplitude reduction and velocity at 2-6 months consistent with preoperative severity.These

2013 Journal of clinical neuromuscular disease Controlled trial quality: uncertain

150. Impact of carpal tunnel surgery according to pre-operative abnormality of sensory conduction in median nerve: a longitudinal study. Full Text available with Trip Pro

Impact of carpal tunnel surgery according to pre-operative abnormality of sensory conduction in median nerve: a longitudinal study. We have previously proposed that sensory nerve conduction (SNC) in the median nerve should be classed as abnormal when the difference between conduction velocities in the little and index fingers is > 8 m/s. In a prospective longitudinal study, we investigated whether this case definition distinguished patients who were more likely to benefit from surgical

2013 BMC Musculoskeletal Disorders

151. Effect of hyperglycemia on conduction parameters of tibial nerve's fibers to different muscles: A rat model Full Text available with Trip Pro

fiber groups may be more seriously affected.14 rats ( 7 diabetic, 7 control) were studied. Tibial nerve was stimulated from two points and while recorded from a distal (foot intrinsic muscles) and a proximal (gastrocnemius) muscle.There was a significant difference between the proximal and distal recorded conduction velocities. Both proximal and distal recorded conduction velocities decreased during the hyperglycemic process.Our method successfully demonstrated different nerve fiber groups (...) Effect of hyperglycemia on conduction parameters of tibial nerve's fibers to different muscles: A rat model Routine conduction studies reflect the summation of all nerve fibers in a peripheral nerve. Nerve fiber groups to distal, small muscles have smaller diameters than the ones to large proximal muscles. There may be minimal differences between the diameters of nerve fiber groups innervating different muscles; even they are all same type of fibers. So, in neuropathic processes some nerve

2013 Journal of neurosciences in rural practice

152. Comparative effects of implanted electrodes with differing contact patterns on peripheral nerve regeneration and functional recovery. (Abstract)

contact; whole-circle contact; no electrodes as control). Electrical stimulation was performed and electrophysiological, morphological and histological exams (of the sciatic nerve and muscle) were conducted at 4 and 10 weeks post-implantation. Point and 1/4 circle contact groups showed significantly higher scores in the sciatic functional index (SFI), increased amplitude of compound muscle action potential (AMP) and motor nerve conduction velocity (MNCV) compared to the control group at both 4 and 10 (...) Comparative effects of implanted electrodes with differing contact patterns on peripheral nerve regeneration and functional recovery. Electrical stimulation could enhance nerve regeneration and functional recovery. The objective of this study was to evaluate the regenerative effects of implanted electrodes with different contacts in resected sciatic nerve. Sciatic nerve resection and microsurgical repair models were established and randomly divided into four groups (point contact, 1/4 circle

2018 Neuroscience research Controlled trial quality: uncertain

153. Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee

Experimental: Fasinumab Drug: Fasinumab Subcutaneous (SC) every four weeks (Q4W) Other Name: REGN475 Placebo Comparator: Placebo Other: Placebo Subcutaneous (SC) every four weeks (Q4W) Outcome Measures Go to Primary Outcome Measures : Change in peroneal motor nerve conduction velocity [ Time Frame: Baseline to week 16 ] An electrophysiological evaluation using standard electrophysiological techniques to measure the speed and extent of nerve conduction Change in peroneal motor nerve action potential (...) amplitude [ Time Frame: Baseline to week 16 ] An electrophysiological evaluation using standard electrophysiological techniques to measure the speed and extent of nerve conduction Change in sural sensory nerve conduction velocity [ Time Frame: Baseline to week 16 ] An electrophysiological evaluation using standard electrophysiological techniques to measure the speed and extent of nerve conduction Change in sural sensory nerve action potential amplitude [ Time Frame: Baseline to week 16

2018 Clinical Trials

154. The Effects of Chicken Embryo Brain Extract on Sciatic Nerve Regeneration of Male Rat; An Experimental Study Full Text available with Trip Pro

was significantly greater than that of the NS group on days 28 and 90 after surgery (p=0.034). At days 28 and 90 after surgery, the mean nerve conduction velocity (NCV) in the BE group was significantly faster than that of the NS group (p=0.041).These results indicate for the first time that chick embryo brain extract can enhance peripheral nerve regeneration in rat. (...) The Effects of Chicken Embryo Brain Extract on Sciatic Nerve Regeneration of Male Rat; An Experimental Study To determine the effects of chicken embryo brain extract (BE) on transects sciatic nerve in male rats.Thirty adult male Sprague-Dawley rats weighing 200 to 250 g, were randomized into three groups treated with (1) sham surgery, (2) normal saline (NS), and (3) brain extract (BE). The BE was taken from incubating chick embryos at day 8. The sciatic nerve was exposed and sharply transected

2018 Bulletin of emergency & trauma

155. Decompression nerve surgery for diabetic neuropathy: a structured review of published clinical trials Full Text available with Trip Pro

improvement in the sham leg comparable to the DNS leg and exceeding the improvement observed in the nonsurgical leg in the unblinded study. Sensory testing showed generally favorable results supporting DNS, and nerve conduction velocities increased post-DNS relative to deterioration in controls. Ultrasound revealed fusiform nerve swelling near compression sites. Morphological results of DNS were generally favorable but inconsistent, whereas hemodynamic measures showed a positive effect on arterial (...) parameters, as did transcutaneous oximetry (improved microcirculation). The incidence of initial and recurrent neuropathic diabetic foot ulcers appeared reduced post-DNS relative to the contralateral foot (borderline significant).The data remain insufficient to recommend DNS for painful DPN, given conflicting and unexpectedly positive results involving sham surgery relative to unblinded controls. The generally supportive sensory and nerve conduction results are compromised by methodological issues

2018 Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy

156. Administration of CoCl2 Improves Functional Recovery in a Rat Model of Sciatic Nerve Transection Injury Full Text available with Trip Pro

into three groups and treated with sham surgery, surgery with cobalt chloride (CoCl2) and surgery with saline, respectively. Sciatic functional index, morphologic evaluations of muscle fibers, and never conduction velocity were performed to measure the functional recovery at 12 weeks postoperatively. In addition, the effects of CoCl2 on the expression of HIF-1α, glial cell line-derived neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) were determined (...) Administration of CoCl2 Improves Functional Recovery in a Rat Model of Sciatic Nerve Transection Injury Peripheral nerve injury is known to activate the hypoxia-inducible factor-1α (HIF-1α) pathway as one of pro-regenerative transcriptional programs, which could stimulate multiple injury-induced gene expression and contribute to axon regeneration and functional recovery. However, the role of HIF-1α in peripheral nerve regeneration remains to be fully elucidated. In this study, rats were divided

2018 International journal of medical sciences

157. A novel chronic nerve compression model in the rat Full Text available with Trip Pro

decrease in nerve conduction velocity at 2 weeks after surgery. Neuropathological studies demonstrated that the model caused nerve demyelination and axonal irregularities and triggered collagen deposition in the epineurium and perineurium of the affected nerve at 8 weeks after surgery. The degree of fibrosis in the gastrocnemius and intrinsic paw muscles was significantly increased at 20 weeks after surgery. In conclusion, our novel model can reproduce the functional and histological changes of chronic (...) was produced. Control pups with latex or N-butyl-cyanoacrylate were also prepared. Functional changes to nerves were assessed using the hot plate test and electromyography. Immunofluorescence and electron microscopy analyses of the nerves were performed to quantify the degree of neuropathological change. Masson staining was conducted to assess the degree of fibrosis in the gastrocnemius and intrinsic paw muscles. The pup group rats subjected to nerve compression displayed thermal hypoesthesia and a gradual

2018 Neural Regeneration Research

158. Presentation and Treatment of a Combined Median Nerve Schwannoma and a C7 Discogenic Radiculopathy Full Text available with Trip Pro

numbness. Clinical investigation revealed a prominent C6-7 disc herniation and a median nerve sheath tumor, with electromyography (EMG)/nerve conduction velocity (NCV) studies suggestive of acute radiculopathy. He was treated in a staged surgical fashion, with the nerve sheath tumor resection first, followed by a standard C6-7 anterior cervical discectomy and fusion (ACDF) two weeks later. The patient made a full recovery. We provide a literature review and discussion of the "double crush" hypothesis. (...) Presentation and Treatment of a Combined Median Nerve Schwannoma and a C7 Discogenic Radiculopathy Cervical radiculopathy and peripheral nerve pathology often compete in the differential diagnosis of extremity pain, weakness, and numbness, and frequently, coexist. In this report, we describe a 73-year-old male with a previously asymptomatic left anteromedial proximal upper arm mass, who presented with progressive radicular arm pain, proximal and distal upper extremity weakness, and hand

2018 Cureus

159. Overexpression of Neuregulin-1 (NRG-1) Gene Contributes to Surgical Repair of Brachial Plexus Injury After Contralateral C7 Nerve Root Transfer in Rats Full Text available with Trip Pro

. The number of nerve fibers and typical area of the affected side were assessed. Postoperative left motor nerve conduction velocity (MNCV) and motor nerve action potential (MNAP) were tested by use of a biological information recording and collecting system. RESULTS Eukaryotic expression plasmid of pcDNA4/myc/A-NRG-1 was successfully constructed, and NRG-1 was overexpressed. Compared with the model group, the NRG-1 group had a lower rate of differences of the limbs; higher mass of left latissimus dorsi (...) Overexpression of Neuregulin-1 (NRG-1) Gene Contributes to Surgical Repair of Brachial Plexus Injury After Contralateral C7 Nerve Root Transfer in Rats BACKGROUND Surgeons usually transfer the contralateral C7 to the median nerve on the injured side via a nerve graft to recover sensation and movement in a paralyzed hand. The purpose of our study was to determine whether NRG-1 affects the recovery of nerve function in brachial plexus injury after contralateral C7 nerve root transfer in a rat

2018 Medical science monitor : international medical journal of experimental and clinical research

160. Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis Full Text available with Trip Pro

, sciatic and vagus nerves of septic (CLP group) and control (sham group) rats were removed, and selected electric stimulations were applied to measure the parameters of the first and second components of the compound action potential. The first component originated from fibers with motor and sensory functions (Types Aα and Aβ fibers) with a large conduction velocity (70-120 m/s), and the second component originated from fibers (Type Aγ) with sensorial function. To evaluate the presence of sensorial (...) Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis Nonspecific and delayed diagnosis of neurologic damage contributes to the development of neuropathies in patients with severe sepsis. The present study assessed the electrophysiologic parameters related to the excitability and conductibility of sciatic and vagus nerves during early stages of sepsis.Twenty-four hours after sepsis induced by cecal ligation and puncture (CLP) model

2018 Journal of pain research

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