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Nerve Conduction Velocity

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101. Electrophysiological aspects of sensory conduction velocity in healthy adults. 1. Conduction velocity from digit to palm, from palm to wrist, and across the elbow, as a function of age. Full Text available with Trip Pro

Electrophysiological aspects of sensory conduction velocity in healthy adults. 1. Conduction velocity from digit to palm, from palm to wrist, and across the elbow, as a function of age. The sensory conduction velocity from digit to palm and from palm to wrist was determined in median (digit 3) and ulnar (digit 5) nerves in 47 healthy subjects with age range from 21 to 77 years. The decrement of the sensory conduction as a function of age was more marked in the palm to wrist than in the digit (...) to palm segment. Sensory conduction velocity of the ulnar nerve across the elbow was also studied. Irregularities in the shape of the sensory evoked potential recorded above the cubital sulcus were found in 12.76% of cases, especially in subjects over 50 years of age. These results suggest that aging causes decrement in sensory conduction and changes in the shape of the evoked potentials, especially at points where the nerves are more frequently compressed.

1978 Journal of neurology, neurosurgery, and psychiatry

102. Electrophysiological and functional evaluation of peroneal nerve regeneration in rabbit following topical hyaluronic acid or tacrolimus application after nerve repair. Full Text available with Trip Pro

repair and toe-spreading index (TSI) experiments were conducted at 4, 8 and 12 weeks after nerve repair.Motor nerve conduction velocity (MNCV) was improved in Groups II and III compared to Group I, but no differences between Groups II and III were observed. After 12 weeks, however, the MNCV in Groups I, II and III was 40.04%, 51.16% and 50.42%, respectively, of that in the control group (100%). In addition, at 12 weeks, Grade 4 TSI scores were observed in Groups II and III.Electrophysiological (...) Electrophysiological and functional evaluation of peroneal nerve regeneration in rabbit following topical hyaluronic acid or tacrolimus application after nerve repair. To investigate and compare the effects of hyaluronic acid (HA), tacrolimus (FK-506) and saline on peripheral nerve regeneration in vivo after topical application at the site of nerve repair.In the present study, 48 adult male European rabbits (Oryctolagus cuniculus), ranging in weight from 2.5 to 3 kg, were randomly assigned

2019 The Nigerian Postgraduate Medical Journal Controlled trial quality: uncertain

103. Histological, electrophysiological and clinical effects of thermal radiofrequency therapy of the saphenous nerve and pulsed radiofrequency therapy of the sciatic nerve in dogs. (Abstract)

and if sciatic nerve PRF induces degeneration or dysfunction.Blinded, controlled, randomized, preclinical study.A group of six intact, female Beagle dogs aged 14-16 months.In each dog, one pelvic limb was assigned randomly to the control group and the other to the treatment group. Dogs were anesthetized and, using ultrasonography, radiofrequency electrodes were positioned adjacent to saphenous and sciatic nerves bilaterally; TRF and PRF were performed only in the treatment limb. Motor nerve conduction (...) velocity (MNCV) was measured in both sciatic nerves 2 weeks later, and the dogs were euthanized. Hematoxylin and eosin-stained sections of saphenous and sciatic nerves were examined using light microscopy. Degeneration and inflammation were scored 0 (none) to 3 (severe). A one-tailed, paired Wilcoxon signed-rank test was used to test for differences in scores and MNCV between control and treatment nerves.Degeneration and inflammation scores were higher in treatment saphenous nerves in 5/6 dogs [83%; 95

2019 Veterinary anaesthesia and analgesia Controlled trial quality: predicted high

104. Impact of hyponatremia on nerve conduction and muscle strength. (Abstract)

mild-to-moderate hyponatremia before and after the normalization of natremia. In the second part, we measured nerve conduction velocities and F-wave latencies in nine patients with profound hyponatremia (< 125 mmol/L) before and after the normalization of natremia.No significant change in muscle strength was observed when natremia was corrected from 127·7 ± 2·5 to 136·1 ± 1·8 mmol/L, contrary to a significant improvement in TUG from 14·9 ± 5·1 to 12·5 ± 4·7 s (P = 0·006). Nerve conduction (...) velocities and F-wave latencies showed significant improvement in most of the studied nerves when natremia was corrected from 121·9 ± 2·4 to 135·5 ± 3·4 mmol/L (e.g. mean increase of 14·3% for motor nerve conduction and mean decrease of 21·6% for F-wave latency of left peroneal nerve).Whereas chronic mild-to-moderate hyponatremia has no impact on muscle strength, we demonstrate for the first time an impact of profound hyponatremia on nerve conduction studies. Further studies are needed to ascertain

2016 European journal of clinical investigation

105. Adiponectin, markers of subclinical inflammation and nerve conduction in individuals with recently diagnosed type 1 and type 2 diabetes. Full Text available with Trip Pro

Adiponectin, markers of subclinical inflammation and nerve conduction in individuals with recently diagnosed type 1 and type 2 diabetes. Subclinical inflammation has been implicated in the development of diabetic sensorimotor polyneuropathy (DSPN), but studies using electrophysiological assessment as outcomes are scarce. Therefore, we aimed to investigate associations of biomarkers reflecting different aspects of subclinical inflammation with motor and sensory nerve conduction velocity (NCV (...) ) in individuals with diabetes.Motor and sensory NCV was assessed in individuals with recently diagnosed type 2 (n=352) or type 1 diabetes (n=161) from the baseline cohort of the observational German Diabetes Study. NCV sum scores were calculated for median, ulnar and peroneal motor as well as median, ulnar and sural sensory nerves. Associations between inflammation-related biomarkers, DSPN and NCV sum scores were estimated using multiple regression models.In type 2 diabetes, high serum interleukin (IL)-6

2016 European Journal of Endocrinology

106. Sciatic Nerve Conductivity is Impaired by Hamstring Strain Injuries. (Abstract)

Sciatic Nerve Conductivity is Impaired by Hamstring Strain Injuries. The aim of this study was to assess sciatic nerve conductivity in athletes with a history of hamstring strain injuries. Twenty-seven athletes with a history of hamstring strain injuries were included in the injured group. The control group consisted of 16 uninjured participants. We measured the proximal and distal latencies and calculated the sciatic nerve conduction velocity to evaluate neuronal conductivity. The results were (...) expressed as median values and interquartile ranges. Both proximal latency and distal latency of the injured limb in the injured group were significantly longer than those of the uninjured limb (p<0.05). The nerve conduction velocity of the injured limb in the injured group was significantly lower than that of the uninjured limb (p<0.05). There were no significant side-to-side differences in the control group. Sciatic nerve conductivity impairments may exist in athletes with a history of hamstring

2017 International Journal of Sports Medicine

107. The Effect of the Silicone Ring Tourniquet and Standard Pneumatic Tourniquet on the Motor Nerve Conduction, Pain and Grip Strength in Healthy Volunteers Full Text available with Trip Pro

parameters of median nerve conduction: motor conduction velocity (MCV), latency (LAT) and amplitude (AMP).Pain score at the time of tourniquet application was higher in SRT group but the alteration in pain scores in PT group was higher, with statistical significance (P<0.05). The grip strength was reduced by the application of both tourniquets; however there was a significantly higher reduction in the SRT group (P<0.05). The conduction impairment of the median nerve was worse in the PT group than (...) The Effect of the Silicone Ring Tourniquet and Standard Pneumatic Tourniquet on the Motor Nerve Conduction, Pain and Grip Strength in Healthy Volunteers The pneumatic tourniquet (PT) is routinely used in upper and lower limb operations by most orthopaedic surgeons. The silicone ring tourniquet (SRT) was introduced in clinical practice over the last decade. Clinical as well as comparative studies have been published in volunteers concerning its safety and efficacy. The aim of this study

2016 Archives of bone and joint surgery

108. Quantitative assessment of chemotherapy‐induced peripheral neurotoxicity using a point‐of‐care nerve conduction device Full Text available with Trip Pro

of diabetic peripheral neuropathy. Sensory nerve action potential (SNAP) amplitude and sensory nerve conduction velocity (SNCV) of the sural nerve were measured using a portable, automated POCD (DPNCheck; NeuroMetrix Inc., Waltham, MA, USA) in patients with a clinical diagnosis of CIPN of grade 1 or higher. We compared SNAP and SNCV among patients with different grades of CIPN according to the Common Terminology Criteria for Adverse Events. A total of 50 patients (22 men, 28 women; median age, 64 years (...) Quantitative assessment of chemotherapy‐induced peripheral neurotoxicity using a point‐of‐care nerve conduction device Chemotherapy-induced peripheral neurotoxicity (CIPN) seriously impairs patients' quality of life cumulatively and dose-dependently. Because assessment of CIPN usually depends on patients' subjective evaluation of symptoms, objective and quantitative measures are needed. We evaluated a point-of-care nerve conduction device (POCD), previously validated for the assessment

2016 Cancer science

109. The Relationship between Nerve Conduction Study and Clinical Grading of Carpal Tunnel Syndrome Full Text available with Trip Pro

The Relationship between Nerve Conduction Study and Clinical Grading of Carpal Tunnel Syndrome Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment. Subjective sensory symptoms are common place in patients with CTS, but sometimes they are not supported by objective findings in the neurological examination. Electrodiagnostic (EDx) studies are a valid and reliable means of confirming the diagnosis. The amplitudes along with the conduction velocities of the sensory nerve action (...) patients (32%) had mild CTS, 25 (50%) had moderate CTS and 9 (18%) had severe CTS clinically. Prolongation of motor latency, latency difference between median and ulnar amplitudes, motor and sensory nerve conduction velocities, sensory latency between median and ulnar nerves, sensory nerve conduction velocities showed significant changes in comparison with controls. Among them sensory latency difference between median and ulnar nerves and sensory nerve conduction velocities are the most sensitive

2016 Journal of clinical and diagnostic research : JCDR

110. Diagnostic Significance of Ultrasonographic Measurements and Median-Ulnar Ratio in Carpal Tunnel Syndrome: Correlation with Nerve Conduction Studies Full Text available with Trip Pro

of the parameters were positively correlated with the distal latency of the compound muscle action potential, and all of them except for SR were negatively correlated with the sensory nerve conduction velocity. A CSA(pisiform)/CSA(ulnar) ratio of ≥1.79 had a sensitivity of 70% and a specificity of 76% for diagnosing CTS.Only CSA(pisiform) measurements were reliable for diagnosing early stages of CTS, and CSA(pisiform)/CSA(ulnar) had a lower diagnostic value for diagnosing CTS. (...) Diagnostic Significance of Ultrasonographic Measurements and Median-Ulnar Ratio in Carpal Tunnel Syndrome: Correlation with Nerve Conduction Studies We determined the reliability of ultrasonography (US) measurements for diagnosing carpal tunnel syndrome (CTS) and their correlation with symptom duration and electrophysiology findings. We determined whether the ratio of the median-to-ulnar cross-sectional areas (CSAs) can support CTS diagnoses.The pisiform CSA (CSA(pisiform)), swelling ratio (SR

2016 Journal of clinical neurology (Seoul, Korea)

111. Four‐year sequential nerve conduction changes since first visit in Japanese patients with early type 2 diabetes Full Text available with Trip Pro

diabetes who newly visited Naka Memorial Clinic, Ibaraki, Japan, and underwent serial 4-year NCS. Records of clinical profile, signs and symptoms of neuropathy, and NCS data from median and tibial nerves were extracted to determine the progression of neuropathy. NCS data were represented by motor nerve conduction velocities, amplitudes of compound muscle action potentials (CMAPs) and minimal latencies of F-wave.The prevalence of clinical neuropathy in 158 cases was 30% at baseline and 29% at the end (...) of the study, with improvement of glycated hemoglobin (8.6-6.9%). Over 4 years, there were no changes of the signs and symptoms of neuropathy. Motor nerve conduction velocities were slightly improved or consistent at the fourth year compared with those at the beginning (+1.5% in median nerve, P < 0.05; +0.8%, not significant in the tibial nerve). The extent of the glycated hemoglobin correction correlated with the improvement of motor nerve conduction velocity. In contrast, CMAPs of both median and tibial

2016 Journal of Diabetes Investigation

112. Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction Full Text available with Trip Pro

as a very specific neuropathology. Septin filaments thus serve an important function in scaffolding the axon/myelin-unit, evidently a late stage of myelin maturation. We propose that pathological or aging-associated diminishment of the septin/anillin-scaffold causes myelin outfoldings that impair the normal nerve conduction velocity. (...) Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction Myelination of axons facilitates rapid impulse propagation in the nervous system. The axon/myelin-unit becomes impaired in myelin-related disorders and upon normal aging. However, the molecular cause of many pathological features, including the frequently observed myelin outfoldings, remained unknown. Using label-free quantitative proteomics, we find that the presence of myelin outfoldings correlates

2016 eLife

113. Descriptive Analysis of Morphological Aspects of Nerve by Ultra-high Frequency Ultrasound (30-50MHZ) in Demyelinating Neuropathies: Inflammatory Demyelinating Polyneuropathy Chronic (IPDC), Neuropathy Multifocal Motor Block of Conducting (NMMBC) and Neuro

Descriptive Analysis of Morphological Aspects of Nerve by Ultra-high Frequency Ultrasound (30-50MHZ) in Demyelinating Neuropathies: Inflammatory Demyelinating Polyneuropathy Chronic (IPDC), Neuropathy Multifocal Motor Block of Conducting (NMMBC) and Neuro Descriptive Analysis of Morphological Aspects of Nerve by Ultra-high Frequency Ultrasound (30-50MHZ) in Demyelinating Neuropathies: Inflammatory Demyelinating Polyneuropathy Chronic (IPDC), Neuropathy Multifocal Motor Block of Conducting (...) latency for distal motor conduction, the motor conduction velocities, the presence of time dispersion or of a conduction block to the stepped motor conduction, the latency of the waveform F to the proximal motor conduction and the amplitude of the sensory potential for sensory conduction. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 40 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking

2016 Clinical Trials

114. Local Effects of Acupuncture and Nerve Conduction Studies

velocities (NCV) post-acupuncture compared to pre-acupuncture [ Time Frame: Week 1, Week 2 ] Nerve conduction studies (NCS) will be performed pre- and post-acupuncture, according to OHSU's EMG laboratory guidelines, using the Dantec Keypoint® G4 Workstation (Natus Medical Incorporated). Subject skin temperature will be maintained above 32C, using a heating pad to warm up a cold hand if needed. Median and Ulnar nerve nerve conduction velocities (NCV) will be measured in meters/second (m/s). Post (...) Local Effects of Acupuncture and Nerve Conduction Studies Local Effects of Acupuncture and Nerve Conduction Studies - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Local Effects of Acupuncture and Nerve

2016 Clinical Trials

115. Effects of Pulsed Ultrasound Therapy on Sensory Nerve Conduction Parameters and the Pain Threshold Perceptions in Humans. (Abstract)

, randomized, single blind, crossover study.Outpatient clinic of a university department of physical medicine and rehabilitation.Twelve healthy volunteers between 22 and 38 years of age (8 male, 4 female).Each patient (blinded) received ultrasound therapy (1W/cm2, pulsed: 1:5; over the course of the superficial branch of the radial nerve of the nondominant arm) and placebo (intensity: zero). The interval between the individual interventions was 1 week.The sensory nerve conduction velocity, sensory nerve (...) Effects of Pulsed Ultrasound Therapy on Sensory Nerve Conduction Parameters and the Pain Threshold Perceptions in Humans. Therapeutic ultrasound is an often-used clinical modality in the nonsurgical treatment of entrapment neuropathies. To date, the possible mechanism of action of pulsed ultrasound therapy on the peripheral nerve in the treatment of entrapment neuropathies is unclear.To examine the effects of pulsed ultrasound therapy on peripheral nerve conduction parameters.A prospective

2016 PM & R : the journal of injury, function, and rehabilitation Controlled trial quality: uncertain

116. The Effect of Light Therapy on Superficial Radial Nerve Conduction Using a Clustered Array of Infrared Super luminous Diodes and Red Light Emitting Diodes. Full Text available with Trip Pro

the application of light irradiation. Negative peak latency (NPL) and conduction velocity (NCV) for the superficial radial nerve were measured before treatment and for 10-minutes following treatment at 2-minute intervals. Skin temperature was monitored throughout.No significant differences between groups and over time for NPL, NCV, or temperature difference scores were identified. However, a significant increase in skin temperature was measured over time at each time point compared to baseline.Light (...) The Effect of Light Therapy on Superficial Radial Nerve Conduction Using a Clustered Array of Infrared Super luminous Diodes and Red Light Emitting Diodes. Lasers, light emitting diodes (LEDs) and super luminous diodes (SLDs) are widely used to treat selected musculoskeletal, integumentary and neurological conditions.The mechanisms underlying the reported treatment effects of light therapy are unclear and the physiologic effect of light on a variety of tissues, particularly neurological

2015 Journal of lasers in medical sciences Controlled trial quality: uncertain

117. Palm to Finger Ulnar Sensory Nerve Conduction Full Text available with Trip Pro

Palm to Finger Ulnar Sensory Nerve Conduction Ulnar neuropathy at the wrist (UNW) is rare, and always challenging to localize. To increase the sensitivity and specificity of the diagnosis of UNW many authors advocate the stimulation of the ulnar nerve (UN) in the segment of the wrist and palm. The focus of this paper is to present a modified and simplified technique of sensory nerve conduction (SNC) of the UN in the wrist and palm segments and demonstrate the validity of this technique (...) in the study of five cases of type III UNW. The SNC of UN was performed antidromically with fifth finger ring recording electrodes. The UN was stimulated 14 cm proximal to the active electrode (the standard way) and 7 cm proximal to the active electrode. The normal data from amplitude and conduction velocity (CV) ratios between the palm to finger and wrist to finger segments were obtained. Normal amplitude ratio was 1.4 to 0.76. Normal CV ratio was 0.8 to 1.23.We found evidences of abnormal SNAP amplitude

2015 Neurology international

118. Cordycepin Decreases Compound Action Potential Conduction of Frog Sciatic Nerve In Vitro Involving Ca2+-Dependent Mechanisms Full Text available with Trip Pro

of cordycepin on CNAP conduction should be elucidated. In this study, the conduction ability of CNAP in isolated frog sciatic nerves was investigated. Results revealed that cordycepin significantly decreased CNAP amplitude and conductive velocity in a reversible and concentration-dependent manner. At 50 mg/L cordycepin, CNAP amplitude and conductive velocity decreased by 62.18 ± 8.06% and 57.34% ± 6.14% compared with the control amplitude and conductive velocity, respectively. However, the depressive action (...) of cordycepin on amplitude and conductive velocity was not observed in Ca(2+)-free medium or in the presence of Ca(2+) channel blockers (CdCl2/LaCl3). Pretreatment with L-type Ca(2+) channel antagonist (nifedipine/deltiazem) also blocked cordycepin-induced responses; by contrast, T-type and P-type Ca(2+) channel antagonists (Ni(2+)) failed to block such responses. Therefore, cordycepin decreased the conduction ability of CNAP in isolated frog sciatic nerves via L-type Ca(2+) channel-dependent mechanism.

2015 Neural plasticity

119. Scaffoldless tissue-engineered nerve conduit promotes peripheral nerve regeneration and functional recovery after tibial nerve injury in rats Full Text available with Trip Pro

on embryonic day 15 (E15). EFCs were fabricated utilizing primary fibroblasts only. Following a 12-week recovery, nerve repair was assessed by measuring contractile properties in the medial gastrocnemius muscle, distal motor nerve conduction velocity in the lateral gastrocnemius, and histology of muscle and nerve. The autografts, ENCs and EFCs reestablished 96%, 87% and 84% of native distal motor nerve conduction velocity in the lateral gastrocnemius, 100%, 44% and 44% of native specific force of medical (...) Scaffoldless tissue-engineered nerve conduit promotes peripheral nerve regeneration and functional recovery after tibial nerve injury in rats Damage to peripheral nerve tissue may cause loss of function in both the nerve and the targeted muscles it innervates. This study compared the repair capability of engineered nerve conduit (ENC), engineered fibroblast conduit (EFC), and autograft in a 10-mm tibial nerve gap. ENCs were fabricated utilizing primary fibroblasts and the nerve cells of rats

2017 Neural Regeneration Research

120. The neural regeneration effect of chitin biological absorbable tubes bridging sciatic nerve defects with sural nerve grafts Full Text available with Trip Pro

and morphology of regenerating myelinated fibers, nerve function index, nerve conduction velocity, and motor end plate and triceps surae muscle morphology were evaluated.The number and morphology of regenerated fibers, nerve function index, nerve conduction velocity, and motor end plate and triceps surae muscle morphology were improved in rats in which the nerve defect was bridged with chitin biological absorbable tubes compared with rats in which the defect was repaired without tubes.The findings suggest (...) The neural regeneration effect of chitin biological absorbable tubes bridging sciatic nerve defects with sural nerve grafts To investigate the feasibility and efficacy of sural nerve grafts for repairing sciatic nerve defects using a chitin biological absorbable tube bridge.A sciatic nerve defect model in the rat was produced, and the sural nerve, cut from the ipsilateral leg, was used as a graft to repair the defect using chitin biological absorbable tube bridges. Then the number

2018 American journal of translational research

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