Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
How to Trip Rapid Review
Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)
Step 2: press
Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.
Motor nerveconductionvelocity in spinal muscular atrophy of childhood. The ulnar and posterior tibial conductionvelocities were measured in 29 children with spinal muscular atrophy, 14 of whom had the servere form of the disease. The ulnar nervevelocity was slow in 12 of the 14 severely affected infants, but normal or fast in 11 of 14 children less severely affected. The corresponding results for the posterior tibial nerve were slow velocities in 11 of 12 infants in the severe group
A study of conductionvelocity in nonmyelinated nerve fibers. By treating a nonmyelinated nerve fiber as a continuous cable consisting of three distinct zones (Resting, transitional, and excited), the following mathematical expression was derived: (formula: see text) where v is the conductionvelocity, d the diameter of the fiber, R the resistance of the membrane of unit area at the peak of excitation, rho the resistivity of the medium inside the fiber, and C the capacity of membrane per unit (...) area. The validity of this expression was demonstrated by using squid giant nerve fibers intracellularly perfused with dilute salt solutions. The relationship between these results and previous theories and experiments on conductionvelocity is discussed.
Motor nerveconductionvelocities in Leigh's encephalomyelopathy. Slowed motor nerveconductionvelocities were found in 3 of 4 cases of Leigh's subacute necrotising encephalopathy. 2 of the patients are sibs, one of whom is clinically normal apart from lactic acidosis and slowed motor nerver conductionvelocities.
The effect of the radiosensitizer misonidazole on motor nerveconductionvelocity in the mouse. The clinical use of misonidazole as a hypoxic cell radiosensitizer is at present limited by its neurotoxicity at high doses (Urtasun et al., 1977; Dische et al., 1977). An in vivo neurological end point, viz. measurement of nerveconductionvelocity, has been developed to examine sensitizer action. Conductionvelocity in mice was measured as a function of time after a single dose of misonidazole (...) and as a function of drug dose. Doses greater than 0.33 mg/g produced significant transient reductions in velocity. The time course of the reduction in velocity closely followed the uptake/excretion profile of misonidazole from blood serum.
Scaling factor relating conductionvelocity and diameter for myelinated afferent nerve fibres in the cat hind limb. 1. Compound action potentials were recorded from certain muscle and cutaneous nerves in normal and chronically de-efferentated hind limbs of cats during stimulation of the appropriate dorsal spinal roots, 2. The peaks for groups I, II and III in the compound action potential were correlated with the corresponding peaks in the fibre-diameter histograms of the same de-efferentated (...) nerve after processing it for light microscopy. 3. The scaling factor (ratio of conductionvelocity in m/sec to total diameter in micrometer) was not constant for all sizes of fibre nor did it increase progressively with fibre size. Evidence is presented that a logarithmic relation between conductionvelocity and fibre diameter is not appropriate. 4. In muscle nerves the scaling factor for fibres fixed by glutaraldehyde perfusion and embedded in Epon was 5.7 for group I afferent fibres and 4.6
Conductionvelocity in the peripheral nerves of rats with chronic carbon disulphide neuropathy. Effects of carbon disulphide (CS2) on conductionvelocity in sciatic and tibial nerve were investigated in rats exposed to CS2 vapour at concentrations of 0.9 mg/l or 1.6 mg/l of air for periods of 1.5, 3, 6, 9 and 12 months. The conductionvelocity was measured on the day following each exposure period, and again, three and six months after the last day of exposure. The majority of exposed rats (...) showed a reduction in conductionvelocity on the day after exposure: the extent of this reduction was dependent on the CS2 concentration and the duration of exposure. Exposure for 1.5 months to 1.6 mg CS2/l produced temporary and fully reversible impairment of conductionvelocity. Increased exposure to CS2 (3,6 or 9 months at 1.6 mg/l; 6 or 12 months at 0.9 mg/l CS2 in air) caused a reduction in velocity which was only partially reversible.
Changes in nerveconductionvelocity in the mouse after acute and chronic administration of nitroimidazoles. The effect of the nitroimidazoles misonidazole, Ro-05-9963, RGW-608 and metronidazole on nerveconductionvelocity (NCV) were measured in the anaesthetized mouse. The compounds were administered by i.p. injection either as a single dose of 1 mg/g (only 0.5 mg/g for RGW-608) or in 36 fractions of 0.15 mg/g over 18 days (only 4 fractions in 2 days for RGW-608). After single doses (...) a reduction in nerveconductionvelocity was seen with all the compounds except metronidazole, which had no significant effect. During chronic exposure, a reduction in NCV occurred towards the end of the course of injections. All compounds produced an effect, although RGW-608 was the most neurotoxic, giving the largest reduction in NCV after only 4 injections. After the end of chronic exposure to misonidazole, Ro-05-9963 and metronidazole, recovery to normal took 2-3 weeks.
The relation between the space constant and conductionvelocity in nerve fibres of the A group from the frog's sciatic 14861824 2004 02 15 2018 12 01 0022-3751 114 3 1951 Jul The Journal of physiology J. Physiol. (Lond.) The relation between the space constant and conductionvelocity in nerve fibers of the A group from the frog's sciatic. 399-409 LUSSIER J J JJ RUSHTON W A H WA eng Journal Article England J Physiol 0266262 0022-3751 OM Animals Anura Humans Nerve Fibers 5120:95379:78 NERVES 1951
The conductionvelocities of respiratory and cardiovascular afferent fibres in the vagus nerve 13085339 2003 05 01 2018 12 01 0022-3751 121 2 1953 Aug The Journal of physiology J. Physiol. (Lond.) The conductionvelocities of respiratory and cardiovascular afferent fibres in the vagus nerve. 341-59 PAINTAL A S AS eng Journal Article England J Physiol 0266262 0022-3751 OM Cardiovascular System Vagus Nerve physiology 5425:6097:316 NERVES, VAGUS/physiology 1953 8 1 1953 8 1 0 1 1953 8 1 0 0
The relationships between conductionvelocity and the diameter and internodal length of peripheral nerve fibres 13429525 2002 05 01 2018 12 01 0022-3751 136 3 1957 May 23 The Journal of physiology J. Physiol. (Lond.) The relationships between conductionvelocity and the diameter and internodal length of peripheral nerve fibres. 606-14 CRAGG B G BG THOMAS P K PK eng Journal Article England J Physiol 0266262 0022-3751 OM Humans Nerve Fibers Peripheral Nerves physiology 5732:27705 NERVES
The relative excitability and conductionvelocity of sensory and motor nerve fibres in man 13320345 2003 05 01 2018 12 01 0022-3751 131 2 1956 Feb 28 The Journal of physiology J. Physiol. (Lond.) The relative excitability and conductionvelocity of sensory and motor nerve fibres in man. 436-51 DAWSON G D GD eng Journal Article England J Physiol 0266262 0022-3751 OM Humans Male Nerve Fibers 5630:28682 NERVES/physiology 1956 2 28 1956 2 28 0 1 1956 2 28 0 0 ppublish 13320345 PMC1363440 Res Publ (...) Assoc Res Nerv Ment Dis. 1952;30:339-70 12983680 Electroencephalogr Clin Neurophysiol. 1954 Feb;6(1):65-84 13141922 J Neurol Neurosurg Psychiatry. 1954 May;17(2):104-14 13163700 Electroencephalogr Clin Neurophysiol Suppl. 1955;Suppl. 4:26-37 13241399 J Physiol. 1951 Apr;113(2-3):240-57 14832772 J Comp Neurol. 1949 Aug;91(1):87-101 15391844 J Neurol Neurosurg Psychiatry. 1949 Nov;12(4):259-67 15397150 J Neurophysiol. 1950 Jan;13(1):39-54 15402625
THE RANGE OF CONDUCTIONVELOCITY IN NORMAL MOTOR NERVE FIBRES TO THE SMALL MUSCLES OF THE HAND AND FOOT 13838014 1998 11 01 2018 12 01 0022-3050 22 1959 Aug Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry The range of conductionvelocity in normal motor nerve fibers to the small muscles of the hand and foot. 175-81 THOMAS P K PK SEARS T A TA GILLIATT R W RW eng Journal Article England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 OM Foot innervation Hand (...) innervation Humans Muscles Nerve Fibers Nervous System Nervous System Physiological Phenomena FOOT/innervation HAND/innervation NERVOUS SYSTEM/physiology 1959 8 1 1959 8 1 0 1 1959 8 1 0 0 ppublish 13838014 PMC497373 J Appl Physiol. 1953 Apr;5(10):589-93 13044736 J Neurol Neurosurg Psychiatry. 1956 Nov;19(4):275-80 13377194 J Physiol. 1954 May 28;124(2):311-24 13175134 Proc R Soc Lond B Biol Sci. 1951 Dec 31;139(894):38-58 14911813 J Neurol Neurosurg Psychiatry. 1958 May;21(2):109-18 13539652
Motor NerveConductionVelocity Determination in the Differential Diagnosis of Neuromuscular Disorders 14007417 1998 11 01 2018 12 01 0027-9684 54 1962 Mar Journal of the National Medical Association J Natl Med Assoc Motor nerveconductionvelocity determination in the differential diagnosis of neuromuscular disorders. 174-8 WILSON R S RS BALLARD L C LC JONES E D ED eng Journal Article United States J Natl Med Assoc 7503090 0027-9684 OM Diagnosis, Differential Disease Electromyography Humans (...) Muscles Muscular Diseases Neural Conduction Neuromuscular Diseases ELECTROMYOGRAPHY MUSCLES/diseases 1962 3 1 1962 3 1 0 1 1962 3 1 0 0 ppublish 14007417 PMC2642394 Arch Neurol Psychiatry. 1948 Oct;60(4):340-65 18111214 J Am Med Assoc. 1957 Mar 30;163(13):1117-24 13405774 J Am Med Assoc. 1960 Apr 30;172:2030-5 14407441
Changes in conductionvelocity and fibre size proximal to peripheral nerve lesions 13696176 1998 11 01 2018 11 30 0022-3751 157 1961 Jul The Journal of physiology J. Physiol. (Lond.) Changes in conductionvelocity and fibre size proximal to peripheral nerve lesions. 315-27 CRAGG B G BG THOMAS P K PK eng Journal Article England J Physiol 0266262 0022-3751 OM Humans Neurons physiology Peripheral Nerves physiology NEURONS/physiology PERIPHERAL NERVES/physiology 1961 7 1 1961 7 1 0 1 1961 7 1 0 0
Further studies of motor nerveconductionvelocity in newborn infants. 5356996 1970 01 24 2008 11 20 1468-2044 44 238 1969 Dec Archives of disease in childhood Arch. Dis. Child. Further studies of motor nerveconductionvelocity in newborn infants. 782-3 Moosa A A eng Journal Article England Arch Dis Child 0372434 0003-9888 IM Gestational Age Humans Infant, Newborn Infant, Newborn, Diseases physiopathology Motor Neurons physiopathology Neural Conduction 1969 12 1 1969 12 1 0 1 1969 12 1 0 0
Conductionvelocity in myelinated nerve fibres of Xenopus laevis 1. The relationship between conductionvelocity and nerve diameter in single myelinated nerve fibres from Xenopus laevis was measured and was found to be linear.2. The relationship between conductionvelocity and temperature in nerve fibres of various diameters was measured over the range 15-30 degrees C and was found to be linear for each fibre.3. The slope of the conductionvelocity-temperature relationship was directly (...) proportional to the diameter of the nerve fibre.4. The form of the conductionvelocity-temperature relationship was determined by numerical solution of the Frankenhaeuser-Huxley equations for the case of a propagated action potential. The computation predicted that conductionvelocity is a linear function of temperature over the range studied.
Nerveconductionvelocity-an index of neurological maturity of the newborn. 5702242 1969 02 20 2008 11 20 1468-2044 43 232 1968 Dec Archives of disease in childhood Arch. Dis. Child. Nerveconductionvelocity-an index of neurological maturity of the newborn. 746 Dubowitz V V eng Journal Article England Arch Dis Child 0372434 0003-9888 IM Birth Weight Gestational Age Humans Infant, Newborn Infant, Premature Leg innervation Neural Conduction Spinal Nerves growth & development Time Factors 1968 12