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Nerve Conduction Velocity

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61. The relationship between nerve conduction velocity and fiber morphology during peripheral nerve regeneration (PubMed)

The relationship between nerve conduction velocity and fiber morphology during peripheral nerve regeneration We analyzed the relationship between motor nerve conduction velocity (MCV) and morphological changes in regenerating nerve fibers at different times after sciatic nerve transection to identify reliable indices of functional recovery. Thirty rats were divided into five equal groups, one control group and four groups subjected to sciatic nerve transection and immediate suturing, followed (...) by regeneration for 50, 100, 150, and 200 days, respectively. MCV was measured in each group, followed by morphometric analyses of fibers of the common peroneal nerve. MCV increased progressively with time after nerve transection, although it remained lower than the control velocity. Mean fiber diameter (axon plus myelin sheath) also increased with time after nerve transection. Recovery of mean fiber diameter was well correlated with MCV, even though regenerating nerves likely contained many small

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2012 Brain and behavior

62. Symptoms, signs and nerve conduction velocities in patients with suspected carpal tunnel syndrome. (PubMed)

Symptoms, signs and nerve conduction velocities in patients with suspected carpal tunnel syndrome. To inform the clinical management of patients with suspected carpal tunnel syndrome (CTS) and case definition for CTS in epidemiological research, we explored the relation of symptoms and signs to sensory nerve conduction (SNC) measurements.Patients aged 20-64 years who were referred to a neurophysiology service for investigation of suspected CTS, completed a symptom questionnaire (including hand (...) . The largest differences in SNC velocities occurred in hands with extensive numbness or tingling in the median nerve sensory distribution and both Tinel's and Phalen's tests positive (mean 13.8, 95% confidence interval (CI) 12.6-15.0 m/s). Hand pain and thumb weakness were unrelated to SNC velocity.Our findings suggest that in the absence of other objective evidence of median nerve dysfunction, there is little value in referring patients of working age with suspected CTS for nerve conduction studies

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2013 BMC Musculoskeletal Disorders

63. Effect of Limb Lengthening on Internodal Length and Conduction Velocity of Peripheral Nerve (PubMed)

Effect of Limb Lengthening on Internodal Length and Conduction Velocity of Peripheral Nerve The influences of axon diameter, myelin thickness, and internodal length on the velocity of conduction of peripheral nerve action potentials are unclear. Previous studies have demonstrated a strong dependence of conduction velocity on internodal length. However, a theoretical analysis has suggested that this relationship may be lost above a nodal separation of ∼0.6 mm. Here we measured nerve conduction (...) not significantly altered by limb lengthening. Despite the substantial increase in internodal length, no significant change was detected in conduction velocity (∼43 m/s) measured either in vivo or in isolated tibial nerves. The results demonstrate that the internode remains plastic in the adult but that increases in internodal length of myelinated adult nerve axons do not result in either deficiency or proportionate increases in their conduction velocity and support the view that the internodal lengths

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2013 The Journal of Neuroscience

64. Sciatic Nerve Conductivity is Impaired by Hamstring Strain Injuries. (PubMed)

Sciatic Nerve Conductivity is Impaired by Hamstring Strain Injuries. The aim of this study was to assess sciatic nerve conductivity in athletes with a history of hamstring strain injuries. Twenty-seven athletes with a history of hamstring strain injuries were included in the injured group. The control group consisted of 16 uninjured participants. We measured the proximal and distal latencies and calculated the sciatic nerve conduction velocity to evaluate neuronal conductivity. The results were (...) expressed as median values and interquartile ranges. Both proximal latency and distal latency of the injured limb in the injured group were significantly longer than those of the uninjured limb (p<0.05). The nerve conduction velocity of the injured limb in the injured group was significantly lower than that of the uninjured limb (p<0.05). There were no significant side-to-side differences in the control group. Sciatic nerve conductivity impairments may exist in athletes with a history of hamstring

2017 International Journal of Sports Medicine

65. Specific changes in conduction velocity recovery cycles of single nociceptors in an erythromelalgia patient with the I848T gain-of-function mutation of NaV1.7. (PubMed)

Specific changes in conduction velocity recovery cycles of single nociceptors in an erythromelalgia patient with the I848T gain-of-function mutation of NaV1.7. Seven patients diagnosed with erythromelalgia (EM) were investigated by microneurography to record from unmyelinated nerve fibers in the peroneal nerve. Two patients had characterized variants of sodium channel Nav1.7 (I848T, I228M), whereas no mutations of coding regions of Navs were found in 5 patients with EM. Irrespective of Nav1.7 (...) mutations, more than 50% of the silent nociceptors in the patients with EM showed spontaneous activity. In the patient with mutation I848T, all nociceptors, but not sympathetic efferents, displayed enhanced early subnormal conduction in the velocity recovery cycles and the expected late subnormality was reversed to supranormal conduction. The larger hyperpolarizing shift of activation might explain the difference to the I228M mutation. Sympathetic fibers that lack Nav1.8 did not show supranormal

2015 Pain

66. Normative values for short-segment nerve conduction studies and ultrasonography of the ulnar nerve at the elbow. (PubMed)

Normative values for short-segment nerve conduction studies and ultrasonography of the ulnar nerve at the elbow. In patients with ulnar neuropathy at the elbow (UNE), short-segment nerve conduction studies (NCS) are rarely performed due to unclear reference values. We excluded controls with subclinical UNE, calculated normative values, and tested them in UNE patients.Clinical examination, ultrasonography (US), and 2-cm short-segment ulnar motor NCS across the elbow were performed in 49 controls (...) and 67 UNE patients. In controls, subclinical UNE was diagnosed if at least 2 studies were outside the reference limits in the same 2-cm segment.Exclusion of controls with subclinical UNE produced less stringent normative values (2-cm conduction velocity: 25 to 31 m/s; US cross-sectional area: 11.6 to 9.6 mm2), which raised diagnostic sensitivity (short-segment NCS: 76% to 90%; 10-cm NCS: 72% to 85%, US: 43% to 79%).We propose the use of our normative values in patients with clinically definite

2015 Muscle & nerve

67. The diagnostic sensitivity of Auditory Brainstem Response (ABR) test and nerve conduction velocity (NCV) test in MucoPolySaccharidosis (MPS): a systematic review and meta-analysis

The diagnostic sensitivity of Auditory Brainstem Response (ABR) test and nerve conduction velocity (NCV) test in MucoPolySaccharidosis (MPS): a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email (...) no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how subgroup variables are stratified etc. In order to assess

2016 PROSPERO

68. A Comparative Study Of Nerve Conduction Velocity Between Left And Right Handed Subjects (PubMed)

A Comparative Study Of Nerve Conduction Velocity Between Left And Right Handed Subjects Nerve conduction velocity is being used as a widespread measure of diagnosis of nerve function abnormalities. Dependence of nerve conduction parameters on intrinsic factors like age and sex, as well as extrinsic factors like temperature is well known. Lateralization of various cerebral functions like speech, language, visuospatial relations, analysis of face, recognition of musical themes and use of hand (...) for fine motor movements have also been studied. Some differences have been noted between left and right hander for nerve conduction. The aim of this study is to compare the nerve conduction velocity between left handed and right handed subjects using median nerve and find out whether there is any difference in nerve conduction velocity (motor or sensory) with handedness.The study was carried out in students of B J Medical College by the use of standard 2 channel physiograph. Comparison of motor

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2012 International journal of basic and applied physiology

69. Nerve Conduction Velocity

Nerve Conduction Velocity Nerve Conduction Velocity Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Nerve Conduction Velocity Nerve (...) Conduction Velocity Aka: Nerve Conduction Velocity , Nerve Conduction Studies , Nerve Conduction Study II. Indication Tests integrity of peripheral nerve myelin and axon Differentiates causes Distribution (single nerve or diffuse involvement) See Causes (e.g. ) (e.g. ) Component of nerve involved (see below) al or axonal EMG slowed out of proportion to nerve conduction Demyelinating or infiltrative Nerve conduction slowed out of proportion to EMG III. Interpretation Axonal (EMG slowed more than NCS

2015 FP Notebook

70. Effect of Parathyroid Hormone and Uremia on Peripheral Nerve Calcium and Motor Nerve Conduction Velocity (PubMed)

Effect of Parathyroid Hormone and Uremia on Peripheral Nerve Calcium and Motor Nerve Conduction Velocity Peripheral neuropathy is not an uncommon complication of chronic uremia. Because parathyroid hormone, by raising brain calcium, is partly responsible for central nervous system aberrations in uremia, we studied the relative role of uremia, per se, and(or) parathyroid hormone on peripheral nerve calcium and motor nerve conduction velocity (MNCV). Studies were made in six groups of six dogs (...) each, as follows: (a) normal dogs, (b) thyroparathyroidectomized (T-PTX) animals, (c) dogs with 3 days of uremia produced by bilateral nephrectomy, (d) T-PTX before the induction of acute renal failure, (e) normal dogs receiving 100 U/day of parathyroid extract (PTE) for 3 days, and (f) normal animals receiving 3 days of PTE followed by 5 days without PTE. Calcium content in peripheral nerve (expressed as milligram per kilogram of dry weight) was 252+/-5 (SE) in normal animals and 262+/-4 in T-PTX

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1978 Journal of Clinical Investigation

71. Scaffoldless tissue-engineered nerve conduit promotes peripheral nerve regeneration and functional recovery after tibial nerve injury in rats (PubMed)

on embryonic day 15 (E15). EFCs were fabricated utilizing primary fibroblasts only. Following a 12-week recovery, nerve repair was assessed by measuring contractile properties in the medial gastrocnemius muscle, distal motor nerve conduction velocity in the lateral gastrocnemius, and histology of muscle and nerve. The autografts, ENCs and EFCs reestablished 96%, 87% and 84% of native distal motor nerve conduction velocity in the lateral gastrocnemius, 100%, 44% and 44% of native specific force of medical (...) Scaffoldless tissue-engineered nerve conduit promotes peripheral nerve regeneration and functional recovery after tibial nerve injury in rats Damage to peripheral nerve tissue may cause loss of function in both the nerve and the targeted muscles it innervates. This study compared the repair capability of engineered nerve conduit (ENC), engineered fibroblast conduit (EFC), and autograft in a 10-mm tibial nerve gap. ENCs were fabricated utilizing primary fibroblasts and the nerve cells of rats

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2017 Neural Regeneration Research

72. Effect of walking and resting after three cryotherapy modalities on the recovery of sensory and motor nerve conduction velocity in healthy subjects. (PubMed)

Effect of walking and resting after three cryotherapy modalities on the recovery of sensory and motor nerve conduction velocity in healthy subjects. Different cryotherapy modalities have distinct effects on sensory and motor nerve conduction parameters. However, it is unclear how these parameters change during the post-cooling period and how the exercise carried out in this period would influence the recovery of nerve conduction velocity (NCV).To compare the effects of three cryotherapy (...) of the modality previously applied (p<0.0001).Cold water immersion was the most effective modality for maintaining reduced sensory nerve conduction after cooling. Walking after cooling, with any of the three modalities, enhances the recovery of sensory and motor NCV.

2011 Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil))

73. Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes. (PubMed)

Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes. The factors influencing the development of impaired sciatic motor nerve conduction velocity (MNCV) in acute experimental diabetes were examined. Decreased MNCV developed by the 14th day after streptozotocin administration but only in rats which became hyperglycemic. Insulin treatment, begun on day 3, failed to prevent imparied MNCV in diabetic rats in which (...) myoinositol (a presumably normal range), sciatic nerve free myoinositol concentrations were 90- and 60-fold higher than those in plasma. On these diets the development of impaired MNCV in the diabetics was associated with a decrease in nerve free myoinositol as compared with nerves from normals fed the same diet, despite similar plasma levels in the normals and diabetics. Plasma and nerve free myoinositol increased with increasing dietary myoinositol content in both normals and diabetics, and nerve

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1975 Journal of Clinical Investigation

74. Free erythrocyte protoporphyrin level and nerve conduction velocity in end-stage renal disease. (PubMed)

Free erythrocyte protoporphyrin level and nerve conduction velocity in end-stage renal disease. Increased free erythrocyte protoporphyrin concentrations and depressed motor nerve conduction velocities (MNCV) were observed in 45 patients on maintenance haemodialysis. Neither of these findings could be correlated with age, duration or frequency of dialysis, or the degree of uraemia present. A strong negative correlation (r=--0-53; P less than 0-001), however, existed between the free erythrocyte (...) protoporphyrin level and the MNCV, which suggested either (a) a direct effect of iron status on nerve function, or (b) a toxic factor in "uraemia" that depresses both nerve conduction and haemsynthetase activity.

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1975 British medical journal

75. Normal ulnar nerve conduction velocity across the thoracic outlet: comparison of two measuring techniques. (PubMed)

Normal ulnar nerve conduction velocity across the thoracic outlet: comparison of two measuring techniques. Comparison of ulnar nerve conduction across the thoracic outlet in 30 normal individuals using caliper and steel tape measurements is reported. A difference of 11.3 m/s was noted between the two methods (58.9 +/- 4.20 m/s by caliper; 70.2 +/- 5.20 m/s by tape). Comparison of these values with previous studies and the use of the opposite limb as a control are discussed. This procedure (...) is of clinical importance in the diagnosis of nerve compression in the thoracic outlet syndrome.

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1975 Journal of neurology, neurosurgery, and psychiatry

76. Conduction velocity along human nociceptive reflex afferent nerve fibres. (PubMed)

Conduction velocity along human nociceptive reflex afferent nerve fibres. The conduction velocity along the nociceptive flexor reflex afferent nerve fibres was investigated in human subjects. The posterior tibal nerve was stimulated at two sites by single painful electrical shocks of 1.0 ms duration and with adequate intensity and the reflex EMG discharges were recorded from the short head of the biceps femoris muscle. The fastest reflex conduction velocity along the posterior tibial nerve (...) between the ankle and the popliteal fossa was about 10-25 m/s. Thus the fastest flexor reflex afferent fibres associated with a painful sensation were thought to be included in the A-delta group of cutaneous afferent nerve fibres.

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1975 Journal of neurology, neurosurgery, and psychiatry

77. Conduction velocity in the proximal segments of a motor nerve in the Guillain-Barré syndrome. (PubMed)

Conduction velocity in the proximal segments of a motor nerve in the Guillain-Barré syndrome. Conduction velocity from spinal cord to axilla (estimated using the F wave) has been compared with conduction velocity from axilla to wrist (measured in the conventional manner) in the motor fibres of the ulnar nerve in 17 controls subjects and in 11 patients with the Guillain-Barré syndrome (GBS). In the patients with GBS the conduction velocity was, in general reduced to a similar extent in both (...) the proximal and the distal portions of the motor fibres, suggesting that the disease process is usually diffuse. In two patients, however, the conduction velocity in the proximal segment was disproportionally reduced and in one of these the conduction velocity in the distal segment was normal. It is concluded that the estimation of conduction velocity in the proximal segments of motor nerves may be of value in the assessment of patients with GBS.

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1976 Journal of neurology, neurosurgery, and psychiatry

78. Effect of chronic renal failure, dialysis and transplantation on motor nerve conduction velocity in children. (PubMed)

Effect of chronic renal failure, dialysis and transplantation on motor nerve conduction velocity in children. Ulnar and peroneal motor nerve conduction volocities (MNCVs) were measured in 47 children in a dialysis-transplantation program. Mean peroneal MNCV was significantly decreased from normal in children with mild renal failure (serum creatinine concentration, 1.5 to 2.9 mg/dl), whereas ulnar MNCV was significantly decreased only when the serum creatinine value was at least 9 mg/dl. Both (...) rapidly returned to normal. These children differed from adults studied in that (a) there was no correlation between severity of renal failure and MNCV, (b) long-term dialysis did not improve MNCV and (c) peroneal velocities did not recover for 3 years after transplantation.

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1975 Canadian Medical Association Journal

79. Letter: Toxic effects on nerve conduction velocity. (PubMed)

Letter: Toxic effects on nerve conduction velocity. 1260296 1976 07 06 2018 11 13 0007-1447 1 6009 1976 Mar 06 British medical journal Br Med J Letter: Toxic effects on nerve conduction velocity. 585 Lauwerys R R Buchet J P JP Roels H H Hubermont G G eng Journal Article England Br Med J 0372673 0007-1447 0 Porphyrins 0 Protoporphyrins AIM IM Humans Kidney Failure, Chronic physiopathology Neural Conduction Porphyrins physiology Protoporphyrins physiology 1976 3 6 1976 3 6 0 1 1976 3 6 0 0

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1976 British medical journal

80. Sciatic nerve motor conduction velocity study. (PubMed)

Sciatic nerve motor conduction velocity study. 6033617 1967 10 07 2018 11 13 0022-3050 30 3 1967 Jun Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Sciatic nerve motor conduction velocity study. 233-9 Yap C B CB Hirota T T eng Journal Article England J Neurol Neurosurg Psychiatry 2985191R 0022-3050 IM S Action Potentials Adult Aged Electric Stimulation Electromyography Female Foot physiology Humans Leg physiology Male Middle Aged Muscles physiology Neural (...) Conduction physiology Reaction Time Sciatic Nerve physiology 1967 6 1 1967 6 1 0 1 1967 6 1 0 0 ppublish 6033617 PMC496174 Brain. 1965 Jun;88(2):335-56 4284013 Arch Neurol. 1966 Jun;14(6):661-9 5935960 J Am Med Assoc. 1960 Apr 30;172:2030-5 14407441 Neurology. 1962 Nov;12:733-44 13934043 Neurology. 1964 Mar;14:222-31 14129051 Neurology. 1963 Dec;13:1021-30 14134175 Neurology. 1964 Jul;14:674-6 14200044 J Neurol Neurosurg Psychiatry. 1964 Aug;27:351-7 14200791 Neurology. 1964 Sep;14:839-43 14215599 Bull

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1967 Journal of neurology, neurosurgery, and psychiatry

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