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Nerve Conduction Velocity

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21. Postoperative improvement in DASH score, clinical findings, and nerve conduction velocity in patients with cubital tunnel syndrome (PubMed)

Postoperative improvement in DASH score, clinical findings, and nerve conduction velocity in patients with cubital tunnel syndrome We investigated a recovery pattern in subjective and objective measures among 52 patients with cubital tunnel syndrome after anterior subcutaneous transposition of the ulnar nerve. Disabilities of the Arm, Shoulder and Hand (DASH) score (primary outcome), numbness score, grip and pinch strength, Semmes-Weinstein (SW) score, static 2-point discrimination (2PD) score (...) , and motor conduction velocity (MCV) stage were examined preoperatively and 1, 3, 6, 12, and ≥24 months postoperatively. Statistical analyses were conducted to evaluate how each variable improved after surgery. A linear mixed-effects model was used for continuous variables (DASH score, numbness, grip and pinch strength), and a proportional odds model was used for categorical variables (SW and 2PD tests and MCV stages). DASH score significantly improved by 6 months. Significant recovery in numbness and SW

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2016 Scientific reports

22. Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity (PubMed)

Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity Myelin controls the time required for an action potential to travel from the neuronal soma to the axon terminal, defining the temporal manner in which information is processed within the CNS. The presence of myelin, the internodal length, and the thickness of the myelin sheath are powerful structural factors that control the velocity and fidelity of action potential transmission. Emerging (...) properties of myelinated fibers. We also demonstrate that genetically attenuating synaptic glutamate neurotransmission from retinal ganglion cells phenocopies the changes observed after monocular deprivation, suggesting that glutamate may constitute a signal for myelin length regulation. Importantly, we demonstrate that visual deprivation and shortened internodes are associated with a significant reduction in nerve conduction velocity in the optic nerve. Our results reveal the importance of sensory input

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2016 The Journal of Neuroscience

23. A Study of Nerve Conduction Velocity in Diabetic Patients and its Relationship with Tendon Reflexes (T-Reflex) (PubMed)

A Study of Nerve Conduction Velocity in Diabetic Patients and its Relationship with Tendon Reflexes (T-Reflex) Neuropathy is one of the most common complications of diabetes mellitus. Neuropathy can cause the sensory deficit, neurological disorder, limb ulcers, osteomyelitis, and amputation. Therefore, neurological examinations, determining the nerve conduction velocity and performing sensory and motor tests are important for timely diagnosis and treatment.The present study aimed to investigate (...) the nerve conduction velocity in diabetic patients and its relationship with tendon reflexes.The present study was observational-cross sectional research carried out on 77 diabetic patients who were admitted into the EMG/NCV Department of Shariati Hospital in the academic year 1996-1997. In all patients, the medical history of the patient (age, duration of diabetes, gender and age of onset of diabetes), neurological examination, nerve conduction velocity, heat test, vibration test, tendon reflexes, D.L

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2018 Open access Macedonian journal of medical sciences

24. Establishing High-Quality Reference Values for Nerve Conduction Studies: A Report from the Normative Data Task Force of the American Association of Neuromuscular & Electrodiagnostic Medicine

also thank Katie McCausland, DO, for assistance with the ulnar and ?bular (peroneal)motornerves. REFERENCES 1. American Association of Electrodiagnostic Medicine. Guidelines in electrodiagnostic medicine. Muscle Nerve 1999;22(suppl):S3–S300. 2. Jablecki CK, Busis NA, Brandstater MA, Krivickas LS, Miller RG, Robinton JE. Reporting the results of needle EMG and nerve con- duction studies: an educational report. Muscle Nerve 2005;32:682– 685. 3. Delisa JA. Manual of nerve conduction velocity (...) . (Reproduced with permission from the AANEM. 11 AANEM Technology Review MUSCLE & NERVE September 2016 36917. Roy PC, Wertsch JJ. Interexaminer variability of distance measurement in nerve conduction studies [abstract]. Muscle Nerve 2007;36:561. 18. Maynard FM, Stolov WC. Experimental error in determination of nerve conduction velocity. Arch Phys Med Rehabil 1972;53:362–372. 19. Nobushige T, Robinson L. Does display sensitivity in?uence motor latency determination? Muscle Nerve 2010;41;309–312. 20. Peng L

2016 American Association of Neuromuscular & Electrodiagnostic Medicine

25. Electrodiagnostic Reference Values for Upper and Lower Limb Nerve Conduction Studies in Adult Populations

, electrodiagnostic; NCS, nerve conduction study; NCV, nerve conduction velocity; NDTF, Normative Data Task Force Key words: guidelines; nerve conduction; nerve conduction studies; nor- mal values; normative data; reference values; standards of practice Disclaimer: This article was prepared and reviewed by the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) and did not undergo separate peer review by Muscle & Nerve. Reviewed by the AANEM Practice Issue Review Panel, April 2016. Approved (...) % of subjects. 8 Sensory nerve conduction veloc- ities were not calculated in the study selected, and another study was cited that examined conduction velocity but did not meet all NDTF criteria. 9,10 Quantile regression was used by this group to pro- vide reference values (cut-offs) for velocities. The third percentiles (lowest cut-off for normality) were 43 m/s, 45 m/s, and 50 m/s for median, ulnar, and radial sensory nerves, respectively. The lower limit of normal for the sural sensory nerve was 40 m/s

2016 American Association of Neuromuscular & Electrodiagnostic Medicine

26. Regulation of myelin structure and conduction velocity by perinodal astrocytes (PubMed)

in the optic nerve. These morphological changes alter the passive cable properties of axons to reduce conduction velocity and spike-time arrival in the CNS in parallel with a decrease in visual acuity. All effects were reversed by the thrombin inhibitor Fondaparinux. Similar results were obtained by viral transfection of tetanus toxin into astrocytes of rat corpus callosum. Previously, it was unknown how the myelin sheath could be thinned and the functions of perinodal astrocytes were not well understood (...) Regulation of myelin structure and conduction velocity by perinodal astrocytes The speed of impulse transmission is critical for optimal neural circuit function, but it is unclear how the appropriate conduction velocity is established in individual axons. The velocity of impulse transmission is influenced by the thickness of the myelin sheath and the morphology of electrogenic nodes of Ranvier along axons. Here we show that myelin thickness and nodal gap length are reversibly altered

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2018 Proceedings of the National Academy of Sciences of the United States of America

27. A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers (PubMed)

consists of microfabricated stimulation and recording microchannel electrode arrays. First, we identify conduction velocities of action potentials traveling through the microchannel and propose a robust data-sorting algorithm using velocity selective recording. We optimize channel geometry and electrode spacing to enhance the algorithm reliability. Second, we demonstrate selective heat-induced neuro-inhibition of peripheral nerve activity upon local illumination of a conjugated polymer (P3HT) blended (...) A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers Peripheral nerves are anisotropic and heterogeneous neural tissues. Their complex physiology restricts realistic in vitro models, and high resolution and selective probing of axonal activity. Here, we present a nerve-on-a-chip platform that enables rapid extracellular recording and axonal tracking of action potentials collected from tens of myelinated fibers. The platform

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2018 Nature communications

28. Partial Conduction Block as an Early Nerve Conduction Finding in Neurolymphomatosis (PubMed)

between symptom onset and the NCS was significantly shorter in the conduction-block group than in the simple-axon-degeneration group (p=0.032). However, no significant differences in the motor nerve conduction velocities, terminal latencies, and distal compound muscle action potential amplitudes were identified between the conduction-block and simple-axon-degeneration groups. The conduction-block group showed excessive temporal dispersion in only five of the ten NCSs (50%). Follow-up NCSs revealed (...) Partial Conduction Block as an Early Nerve Conduction Finding in Neurolymphomatosis Neurolymphomatosis is a rare manifestation of hematological malignancy and is characterized by direct infiltration of the peripheral nervous system. The objective of this study was to identify the clinical and electrophysiological features of neurolymphomatosis.We retrospectively analyzed the medical records of 13 patients with neurolymphomatosis. Seven (54%) of the patients were men, and the median age

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2017 Journal of clinical neurology (Seoul, Korea)

29. Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine (PubMed)

, height, weight, body mass index and leg length were not significantly different between tailors and control groups. Cardio respiratory measurements (SBP, DBP, PR and RR) were also not significantly altered between both the groups. The sensory nerve conduction velocities (m/s) of the right {44.23(42.72-47.83) vs 50(46- 54)} and left sural nerves {45.97±5.86 vs 50.67±6.59} m/s were found significantly reduced in tailors in comparison to control group. Similarly amplitudes (μv) of right sural (20.75 (...) Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine The use of new technologies and innovations are out of access for people living in a developing country like Nepal. The mechanical sewing machine is still in existence at a large scale and dominant all over the country. Tailoring is one of the major occupations adopted by skilled people with lower socioeconomic status and education level. Sural nerves of both right and left legs are exposed to strenuous

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2017 Journal of clinical and diagnostic research : JCDR

30. New Theoretical Model of Nerve Conduction in Unmyelinated Nerves (PubMed)

would be proportionate to the square root of channel density, the conduction velocity of unmyelinated nerves is theoretically shown to be proportionate to the square root of channel density. Also, from a viewpoint of equilibrium state of channel importation and degeneration, channel density was suggested to be proportionate to axonal diameter. Based on these simple basis, conduction velocity in unmyelinated nerves was theoretically shown to be proportionate to the square root of axonal diameter (...) New Theoretical Model of Nerve Conduction in Unmyelinated Nerves Nerve conduction in unmyelinated fibers has long been described based on the equivalent circuit model and cable theory. However, without the change in ionic concentration gradient across the membrane, there would be no generation or propagation of the action potential. Based on this concept, we employ a new conductive model focusing on the distribution of voltage-gated sodium ion channels and Coulomb force between electrolytes

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2017 Frontiers in physiology

31. Peripheral nerve ultrasound changes in CIDP and correlations with nerve conduction velocity. (PubMed)

Peripheral nerve ultrasound changes in CIDP and correlations with nerve conduction velocity. To evaluate the ultrasound (US) characteristics of peripheral nerves in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and their correlations with electrodiagnostic (EDX) characteristics.Nineteen patients with CIDP and 19 healthy controls matched by age and body mass index were included in a blind case-control, observational study. All patients underwent a neurologic examination (...) ) or in segments with normal EDX characteristics (p < 0.0001). NCSA and motor nerve conduction velocity were inversely correlated in nerve segments with EDX evidence of myelin damage (R = 0.599; p < 0.0001). Conduction blocks were associated with increased NCSA (p = 0.001).US may, similar to MRI, have a supporting role in the diagnosis of CIDP. US and EDX changes are correlated.© 2015 American Academy of Neurology.

2015 Neurology

32. Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice. (PubMed)

Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice. Nerve conduction velocity (NCV), the speed at which electrical signals propagate along peripheral nerves, is used in the clinic to evaluate nerve function in humans. A decline in peripheral nerve function is associated with a number of age-related pathologies. While several studies have shown that NCV declines with age in humans, there is little information on the effect of age on NCV in peripheral nerves in mice (...) . In this study, we evaluated NCV in male and female C57Bl/6 mice ranging from 4 to 32 months of age. We observed a decline in NCV in both male and female mice after 20 months of age. Sex differences were detected in sensory NCV as well as the rate of decline during aging in motor nerves; female mice had slower sensory NCV and a slower age-related decline in motor nerves compared with male mice. We also tested the effect of dietary restriction on NCV in 30-month-old female mice. Dietary restriction prevented

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2014 Biological Sciences and Medical Sciences

33. The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial. (PubMed)

, consisting of a 12-week anti-inflammatory diet program, or control group. Outcome measures were assessed at baseline, 1 month, and 3 months and consisted of measures of motor nerve conduction velocity (NCV) and amplitude as well as markers of inflammation as assessed by various pro- and anti-inflammatory cytokines. Results: Despite a significant reduction in inflammation in the treatment group, 2-way repeated measures analysis of variance (ANOVA) showed no significant Group × Time interaction for motor (...) The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial. Objective: To examine the potential influence of chronic inflammation on peripheral motor nerve function in vivo following spinal cord injury (SCI). Methods: This study was part of a randomized, parallel-group, controlled clinical trial. The study included 20 participants with varying levels and severities of SCI randomized (3:2) to either a treatment group

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2018 Topics in spinal cord injury rehabilitation

34. Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial. (PubMed)

Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial. Peripheral neuropathy (PN) is one of the long-term complications of diabetes. Few studies have investigated the role of regular exercise on diabetic PN. We examined the effect of aerobic training on nerve conduction velocity and action potential amplitude in the lower limbs of men with type 2 diabetes and PN.In a randomized controlled study, 24 volunteers (...) conduction velocity (NCV) in the exercise group significantly increased (from 35.2±4.3m/s to 37.3±6.2m/s) compared to the control group (P=0.007). Changes in peroneal and tibial motor NCV and nerve action potential amplitude (NAPA) in all nerves studied were not different between groups (P>0.05). Moreover, HbA1c decreased to a greater extent in the exercise group compared to the control (P=0.014).Aerobic exercise training may have the potential to hinder the progression of diabetic PN by improving NCV

2018 Neurophysiologie clinique = Clinical neurophysiology

35. Effects of Hip Distraction Without a Perineal Post on Venous Blood Flow and Peripheral Nerve Conduction

vascular disease characterized by diminished dorsalis pedis or tibial pulse Significant peripheral neuropathy demonstrated by nerve conduction velocity test Preoperative use of statins or other medications known to elevate serum CPK-MM levels within one week of surgery Total hip replacement of the indicated hip(s) History of substance abuse within past 12 months (this includes any chronic narcotic use) Any significant psychological disturbance past or present, psychotic or neurotic, that could impair (...) Effects of Hip Distraction Without a Perineal Post on Venous Blood Flow and Peripheral Nerve Conduction Effects of Hip Distraction Without a Perineal Post on Venous Blood Flow and Peripheral Nerve Conduction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2018 Clinical Trials

36. A comparison of the effects of agricultural pesticide uses on peripheral nerve conduction in China (PubMed)

described by the reduced velocity. Moreover, the use of organonitrogen compounds by farmers would not only increase risk of demylination disease but axonal damages described by the reduced amplitude. By contrast, agricultural uses of organosulfur and pyrethroid compounds would not induce the abnormalities of farmers' peripheral nerve conduction. The findings demonstrated the importance of developing health-friendly pesticides to replace organophosphorus and organonitrogen insecticides and fungicides (...) A comparison of the effects of agricultural pesticide uses on peripheral nerve conduction in China Evidence on the adverse effects of agricultural pesticide use by farmers under the actual field conditions on their peripheral nerve conduction in China is limited. This study was to investigate the association of agricultural pesticide use with the abnormalities of farmers' peripheral nerve conduction based on two rounds of conventional nerve conduction studies. The level of pesticide exposure

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2018 Scientific reports

37. Normative Ulnar Nerve Conduction Study: Comparison of Two Measurement Methods (PubMed)

of motor conduction velocity of FDI and ADM at forearm and across the elbow among the normal population.In this cross-sectional study, healthy participants were enrolled in the study. Ulnar nerve motor nerve conduction velocity (MNCV) was recorded from the ADM and the FDI at forearm and across the elbow. Mean MNCV of the ulnar nerve recorded from ADM and FDI was compared. In addition, MNCV of the ulnar nerve measured at the forearm and across the elbow was compared also.During this study, 165 healthy (...) Normative Ulnar Nerve Conduction Study: Comparison of Two Measurement Methods Given the high prevalence rate of ulnar neuropathy and importance of its proper management, to have a baseline information about the normative value of motor nerve conduction of first dorsal interosseous (FDI) muscle and abductor digiti minimi muscle (ADM) and their differences as well as their relation with different demographic characteristics of our population, we aimed to determine and compare the mean value

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2018 Advanced biomedical research

38. Multiparity affects conduction properties of pelvic floor nerves in rabbits (PubMed)

-matched nulliparous and multiparous animals and associated to the histological characteristics of myelinated axons from the Bsn and Pcn nerves. The extensor digitorum longus nerve (EDLn) was used as negative control. Data were analyzed with unpaired two-tailed Student's t test or Mann-Whitney U test to determine significant differences between groups.The onset and peak latencies, duration, and conduction velocity of the motor fibers in these pelvic nerves were not significantly different between (...) Multiparity affects conduction properties of pelvic floor nerves in rabbits Women often develop pelvic floor dysfunction due to damage to the pelvic musculature during childbirth; however, the effect on pelvic floor nerves function is less understood. This study used adult rabbits to evaluate the electrophysiological and histological characteristics of the bulbospongiosus (Bsn) and pubococcygeus nerves (Pcn) in multiparity.Compound nerve action potentials (CNAP) were compared between age

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2018 Brain and behavior

39. Effects of prostaglandin E1 plus methylcobalamin alone and in combination with lipoic acid on nerve conduction velocity in patients with diabetic peripheral neuropathy: a meta-analysis. (PubMed)

Effects of prostaglandin E1 plus methylcobalamin alone and in combination with lipoic acid on nerve conduction velocity in patients with diabetic peripheral neuropathy: a meta-analysis. This report was to evaluate the efficacy of lipoic acid, prostaglandin E1 and methylcobalamin (L+P+M) for the treatment of diabetic peripheral neuropathy (DPN) in comparison with that of prostaglandin E1 plus methylcobalamin (P+M), in order to provide the basis and reference for clinical rational drug use (...) of L+P+M therapy on nerve conduction velocities (NCVs) were (fifteen trials; MD 4.70, 95% CI 3.77-5.63, P<0.00001, I(2)=79%) for median MNCV, (thirteen trials; MD 4.73, 95% CI 3.69-5.77, P<0.00001, I(2)=85%) for median SNCV, (sixteen trials; MD 4.22, 95% CI 3.32-5.12, P<0.00001, I(2)=83%) for peroneal MNCV, (fourteen trials; MD 3.09, 95% CI 2.04-4.14, P<0.00001, I(2)=82%) for peroneal SNCV. There was no serious adverse events associated with drugs intervention. L+P+M therapy was superior to P+M

2015 Neuroscience letters

40. Evaluation of sural nerve automated nerve conduction study in the diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus (PubMed)

. Exclusion criteria were B12 depletion, alcohol abuse and other causes of peripheral neuropathy. The reference method was the Neuropathy Disability Score (NDS) with a threshold NDS ≥ 3. Sural nerve automated NCS was carried out with the portable NC-stat DPNCheck device. Sensory nerve conduction velocity and sensory nerve action potential amplitude were measured bilaterally. Automated NCS was considered abnormal when ≥ 1 of the two aforementioned neurophysiological parameters was abnormal in at least one (...) Evaluation of sural nerve automated nerve conduction study in the diagnosis of peripheral neuropathy in patients with type 2 diabetes mellitus New tests for improved diagnosis of diabetic peripheral neuropathy (DPN) are useful.We evaluated the utility of automated nerve conduction study (NCS) of the sural nerve with a new portable device for the diagnosis of DPN in patients with type 2 diabetes mellitus (T2DM). This study included 114 T2DM patients (58 men) with mean age 64.60 ±8.61 years

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2016 Archives of medical science : AMS

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