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Nerve Conduction Velocity

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21. The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus Full Text available with Trip Pro

The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus This study aims to establish the corneal nerve fiber (CNF) morphological alterations in a large cohort of type 2 diabetic patients and to investigate the association between the bead size, a novel parameter representing composite of accumulated mitochondria, glycogen particles, and vesicles (...) . The HbA1c levels were tightly associated with the bead size, which was inversely related to the motor and sensory nerve conduction velocity (NCV) and to the distal latency period of the median nerve positively. The CNF density and length positively correlated with the NCV and amplitude. The hyperglycemia-induced expansion of beads in CNF might be a predictor of slow NCV in peripheral nerves in type 2 diabetic patients.

2016 Journal of diabetes research

22. Validity of a point-of-care nerve conduction device for polyneuropathy identification in older adults with diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. Full Text available with Trip Pro

of a POCD as a proxy for standard nerve conduction studies (NCS) in older adults with type 1 diabetes (T1D).Sural nerve amplitude potential (AMP) and sural nerve conduction velocity (CV) was measured in 68 participants with ≥ 50 years T1D duration and 71 controls (from age/sex-matched subgroups) using POCD and NCS protocols. Agreement was determined by the Bland-Altman method, and validity was determined by receiver operating characteristic curves.T1D were 53% female, aged 66±8yr and had diabetes (...) Validity of a point-of-care nerve conduction device for polyneuropathy identification in older adults with diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. Point-of-care nerve conduction devices (POCD) have been studied in younger patients and may facilitate screening for polyneuropathy in non-specialized clinical settings. However, performance may be impaired with advanced age owing to age-related changes in nerve conduction. We aimed to evaluate the validity

2018 PLoS ONE

23. Electrodiagnostic Reference Values for Upper and Lower Limb Nerve Conduction Studies in Adult Populations

, electrodiagnostic; NCS, nerve conduction study; NCV, nerve conduction velocity; NDTF, Normative Data Task Force Key words: guidelines; nerve conduction; nerve conduction studies; nor- mal values; normative data; reference values; standards of practice Disclaimer: This article was prepared and reviewed by the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) and did not undergo separate peer review by Muscle & Nerve. Reviewed by the AANEM Practice Issue Review Panel, April 2016. Approved (...) % of subjects. 8 Sensory nerve conduction veloc- ities were not calculated in the study selected, and another study was cited that examined conduction velocity but did not meet all NDTF criteria. 9,10 Quantile regression was used by this group to pro- vide reference values (cut-offs) for velocities. The third percentiles (lowest cut-off for normality) were 43 m/s, 45 m/s, and 50 m/s for median, ulnar, and radial sensory nerves, respectively. The lower limit of normal for the sural sensory nerve was 40 m/s

2016 American Association of Neuromuscular & Electrodiagnostic Medicine

24. Establishing High-Quality Reference Values for Nerve Conduction Studies: A Report from the Normative Data Task Force of the American Association of Neuromuscular & Electrodiagnostic Medicine

also thank Katie McCausland, DO, for assistance with the ulnar and ?bular (peroneal)motornerves. REFERENCES 1. American Association of Electrodiagnostic Medicine. Guidelines in electrodiagnostic medicine. Muscle Nerve 1999;22(suppl):S3–S300. 2. Jablecki CK, Busis NA, Brandstater MA, Krivickas LS, Miller RG, Robinton JE. Reporting the results of needle EMG and nerve con- duction studies: an educational report. Muscle Nerve 2005;32:682– 685. 3. Delisa JA. Manual of nerve conduction velocity (...) . (Reproduced with permission from the AANEM. 11 AANEM Technology Review MUSCLE & NERVE September 2016 36917. Roy PC, Wertsch JJ. Interexaminer variability of distance measurement in nerve conduction studies [abstract]. Muscle Nerve 2007;36:561. 18. Maynard FM, Stolov WC. Experimental error in determination of nerve conduction velocity. Arch Phys Med Rehabil 1972;53:362–372. 19. Nobushige T, Robinson L. Does display sensitivity in?uence motor latency determination? Muscle Nerve 2010;41;309–312. 20. Peng L

2016 American Association of Neuromuscular & Electrodiagnostic Medicine

25. Peripheral nerve ultrasound changes in CIDP and correlations with nerve conduction velocity. (Abstract)

Peripheral nerve ultrasound changes in CIDP and correlations with nerve conduction velocity. To evaluate the ultrasound (US) characteristics of peripheral nerves in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and their correlations with electrodiagnostic (EDX) characteristics.Nineteen patients with CIDP and 19 healthy controls matched by age and body mass index were included in a blind case-control, observational study. All patients underwent a neurologic examination (...) ) or in segments with normal EDX characteristics (p < 0.0001). NCSA and motor nerve conduction velocity were inversely correlated in nerve segments with EDX evidence of myelin damage (R = 0.599; p < 0.0001). Conduction blocks were associated with increased NCSA (p = 0.001).US may, similar to MRI, have a supporting role in the diagnosis of CIDP. US and EDX changes are correlated.© 2015 American Academy of Neurology.

2015 Neurology

26. The MTHFR C677T polymorphism influences the efficacy of folic acid supplementation on the nerve conduction studies in patients with diabetic polyneuropathy; A randomized, double blind, placebo-controlled study. Full Text available with Trip Pro

The MTHFR C677T polymorphism influences the efficacy of folic acid supplementation on the nerve conduction studies in patients with diabetic polyneuropathy; A randomized, double blind, placebo-controlled study. Among patients with diabetic polyneuropathy, the status of folic acid, homocysteine, and nerve conduction studies (NCS) variations has been associated with methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms. The objective of the present study is to assess B9 vitamin (...) genotype; 0.5 ± 0.3 vs. 0.3 ± 0.2 for amplitude of tibial nerve between CT + TT genotype; 26.0 ± 13.3 vs. 23.2 ± 13.4 for velocity of tibial nerve between CC genotype; 26.0 ± 13.7 vs. 23.1 ± 9.6 for velocity of tibial nerve between CT + TT genotype; 1.6 ± 1.0 vs. 0.9 ± 0.7 for amplitude of peroneal nerve between CC genotype; 1.4 ± 0.7 vs. 0.9 ± 0.5 for amplitude of peroneal nerve between CT + TT genotype).The study determined that MTHFR C677T polymorphism effects the efficacy of folic acid

2019 Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences Controlled trial quality: uncertain

27. Partial Conduction Block as an Early Nerve Conduction Finding in Neurolymphomatosis Full Text available with Trip Pro

between symptom onset and the NCS was significantly shorter in the conduction-block group than in the simple-axon-degeneration group (p=0.032). However, no significant differences in the motor nerve conduction velocities, terminal latencies, and distal compound muscle action potential amplitudes were identified between the conduction-block and simple-axon-degeneration groups. The conduction-block group showed excessive temporal dispersion in only five of the ten NCSs (50%). Follow-up NCSs revealed (...) Partial Conduction Block as an Early Nerve Conduction Finding in Neurolymphomatosis Neurolymphomatosis is a rare manifestation of hematological malignancy and is characterized by direct infiltration of the peripheral nervous system. The objective of this study was to identify the clinical and electrophysiological features of neurolymphomatosis.We retrospectively analyzed the medical records of 13 patients with neurolymphomatosis. Seven (54%) of the patients were men, and the median age

2017 Journal of clinical neurology (Seoul, Korea)

28. Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs. (Abstract)

Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs. To evaluate the effects of segmental vitiligo (SV) on nerve conduction velocity (NCV) in different nerves, we compared the patient's lesional side of their body to the contralateral normal side. The 106 participants were selected from outpatients visiting the dermatological clinics of Huashan Hospital, Fudan University, from November 2011 to March 2014. NCVs were measured on the limbs and the face, including both (...) motor and sensory nerves. The parameters for NCVs included motor nerve conduction velocity (MCV) and its distal conduction latency, sensory nerve conduction velocity, sensory nerve action potentials amplitude, and compound muscle action potential amplitude. MCV on the limbs was compromised by SV state, which was significantly slower on the lesional side of the body compared with the normal contralateral side (P = 0.006). Furthermore, SV at the stable stage significantly impaired MCV compared

2016 International Journal of Dermatology

29. Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity Full Text available with Trip Pro

Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity Myelin controls the time required for an action potential to travel from the neuronal soma to the axon terminal, defining the temporal manner in which information is processed within the CNS. The presence of myelin, the internodal length, and the thickness of the myelin sheath are powerful structural factors that control the velocity and fidelity of action potential transmission. Emerging (...) properties of myelinated fibers. We also demonstrate that genetically attenuating synaptic glutamate neurotransmission from retinal ganglion cells phenocopies the changes observed after monocular deprivation, suggesting that glutamate may constitute a signal for myelin length regulation. Importantly, we demonstrate that visual deprivation and shortened internodes are associated with a significant reduction in nerve conduction velocity in the optic nerve. Our results reveal the importance of sensory input

2016 The Journal of Neuroscience

30. Motor Nerve Conduction Velocity In Postmenopausal Women with Peripheral Neuropathy Full Text available with Trip Pro

Motor Nerve Conduction Velocity In Postmenopausal Women with Peripheral Neuropathy The post-menopausal phase is characterized by a decline in the serum oestrogen and progesterone levels. This phase is also associated with higher incidence of peripheral neuropathy.To explore the relationship between the peripheral motor nerve status and serum oestrogen and progesterone levels through assessment of Motor Nerve Conduction Velocity (MNCV) in post-menopausal women with peripheral neuropathy.This (...) cross-sectional study was conducted at Jawaharlal Nehru Medical College during 2011-2013. The study included 30 post-menopausal women with peripheral neuropathy (age: 51.4±7.9) and 30 post-menopausal women without peripheral neuropathy (control) (age: 52.5±4.9). They were compared for MNCV in median, ulnar and common peroneal nerves and serum levels of oestrogen and progesterone estimated through enzyme immunoassays. To study the relationship between hormone levels and MNCV, a stepwise linear

2016 Journal of clinical and diagnostic research : JCDR

31. NERVE CONDUCTION VELOCITY IN CMT1A: WHAT ELSE CAN WE TELL Full Text available with Trip Pro

NERVE CONDUCTION VELOCITY IN CMT1A: WHAT ELSE CAN WE TELL Charcot-Marie-Tooth disease (CMT) type 1A is characterized by uniformly reduced nerve conduction velocity (NCV) that is fully penetrant since the first years of life, remains fairly stable through the life and does not correlate with disability whereas compound muscular action potential (CMAP) amplitude does. The aim of the present study was to analyze the large amount of electrophysiological data collected in the ascorbic acid trial (...) in Italy and the UK (CMT-TRIAAL/CMT-TRAUK) and to use these data to gain insights into the pathophysiology of NCV in CMT1A.Baseline electrophysiological data from 271 patients were analysed. Electrophysiological recordings were taken from the motor ulnar, median and peroneal nerves and the sensory ulnar nerve. Distal motor latency (DML), motor (MNCV) and sensory (SNCV) nerve conduction velocity, and amplitudes of CMAPs and sensory action potentials were assessed. Electrophysiological findings were

2016 European Journal of Neurology

32. Postoperative improvement in DASH score, clinical findings, and nerve conduction velocity in patients with cubital tunnel syndrome Full Text available with Trip Pro

Postoperative improvement in DASH score, clinical findings, and nerve conduction velocity in patients with cubital tunnel syndrome We investigated a recovery pattern in subjective and objective measures among 52 patients with cubital tunnel syndrome after anterior subcutaneous transposition of the ulnar nerve. Disabilities of the Arm, Shoulder and Hand (DASH) score (primary outcome), numbness score, grip and pinch strength, Semmes-Weinstein (SW) score, static 2-point discrimination (2PD) score (...) , and motor conduction velocity (MCV) stage were examined preoperatively and 1, 3, 6, 12, and ≥24 months postoperatively. Statistical analyses were conducted to evaluate how each variable improved after surgery. A linear mixed-effects model was used for continuous variables (DASH score, numbness, grip and pinch strength), and a proportional odds model was used for categorical variables (SW and 2PD tests and MCV stages). DASH score significantly improved by 6 months. Significant recovery in numbness and SW

2016 Scientific reports

33. Effect of high-frequency repetitive transcranial magnetic stimulation on motor cortical excitability and sensory nerve conduction velocity in subacute-stage incomplete spinal cord injury patients Full Text available with Trip Pro

Effect of high-frequency repetitive transcranial magnetic stimulation on motor cortical excitability and sensory nerve conduction velocity in subacute-stage incomplete spinal cord injury patients [Purpose] The aim of the present study was to determine whether repetitive transcranial magnetic stimulation can improve sensory recovery of the lower extremities in subacute-stage spinal cord injury patients. [Subjects and Methods] This study was conducted on 20 subjects with diagnosed paraplegia due (...) transcranial magnetic stimulation and conventional rehabilitation therapy. Participants in both groups received therapy five days per week for six-weeks. Latency, amplitude, and sensory nerve conduction velocity were assessed before and after the six week therapy period. [Results] A significant intergroup difference was observed for posttreatment velocity gains, but no significant intergroup difference was observed for amplitude or latency. [Conclusion] repetitive transcranial magnetic stimulation may

2016 Journal of physical therapy science Controlled trial quality: uncertain

34. Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine Full Text available with Trip Pro

, height, weight, body mass index and leg length were not significantly different between tailors and control groups. Cardio respiratory measurements (SBP, DBP, PR and RR) were also not significantly altered between both the groups. The sensory nerve conduction velocities (m/s) of the right {44.23(42.72-47.83) vs 50(46- 54)} and left sural nerves {45.97±5.86 vs 50.67±6.59} m/s were found significantly reduced in tailors in comparison to control group. Similarly amplitudes (μv) of right sural (20.75 (...) Nerve Conduction Study on Sural Nerve among Nepalese Tailors Using Mechanical Sewing Machine The use of new technologies and innovations are out of access for people living in a developing country like Nepal. The mechanical sewing machine is still in existence at a large scale and dominant all over the country. Tailoring is one of the major occupations adopted by skilled people with lower socioeconomic status and education level. Sural nerves of both right and left legs are exposed to strenuous

2017 Journal of clinical and diagnostic research : JCDR

35. New Theoretical Model of Nerve Conduction in Unmyelinated Nerves Full Text available with Trip Pro

would be proportionate to the square root of channel density, the conduction velocity of unmyelinated nerves is theoretically shown to be proportionate to the square root of channel density. Also, from a viewpoint of equilibrium state of channel importation and degeneration, channel density was suggested to be proportionate to axonal diameter. Based on these simple basis, conduction velocity in unmyelinated nerves was theoretically shown to be proportionate to the square root of axonal diameter (...) New Theoretical Model of Nerve Conduction in Unmyelinated Nerves Nerve conduction in unmyelinated fibers has long been described based on the equivalent circuit model and cable theory. However, without the change in ionic concentration gradient across the membrane, there would be no generation or propagation of the action potential. Based on this concept, we employ a new conductive model focusing on the distribution of voltage-gated sodium ion channels and Coulomb force between electrolytes

2017 Frontiers in physiology

36. Dexmedetomidine augments the effect of lidocaine: power spectrum and nerve conduction velocity distribution study. Full Text available with Trip Pro

Dexmedetomidine augments the effect of lidocaine: power spectrum and nerve conduction velocity distribution study. In this study, the individual and combined inhibitory effects of dexmedetomidine and lidocaine on the conduction group of isolated nerve were investigated by determining conduction velocity distribution (CVD) and power spectrum.Electrophysiological compound action potential (CAP) recordings were conducted on isolated rat sciatic nerve before (Con) and 20 minutes after exposure to 1 (...) conducting group significantly while dexmedetomidine did not cause any significant change as compared to Control. Lidocaine, when combined with dexmedetomidine revealed a remarkable effect on the whole CVD histogram by causing almost complete blockage of fast conducting nerve fibers. The relative number of fibers in CVD is conserved for separate applications of anesthetics, but not for their combination. As in CVD, power spectrum shifted from higher to lower frequency region by lidocaine

2015 BMC Anesthesiology

37. Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial. (Abstract)

Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial. Peripheral neuropathy (PN) is one of the long-term complications of diabetes. Few studies have investigated the role of regular exercise on diabetic PN. We examined the effect of aerobic training on nerve conduction velocity and action potential amplitude in the lower limbs of men with type 2 diabetes and PN.In a randomized controlled study, 24 volunteers (...) conduction velocity (NCV) in the exercise group significantly increased (from 35.2±4.3m/s to 37.3±6.2m/s) compared to the control group (P=0.007). Changes in peroneal and tibial motor NCV and nerve action potential amplitude (NAPA) in all nerves studied were not different between groups (P>0.05). Moreover, HbA1c decreased to a greater extent in the exercise group compared to the control (P=0.014).Aerobic exercise training may have the potential to hinder the progression of diabetic PN by improving NCV

2018 Neurophysiologie clinique = Clinical neurophysiology Controlled trial quality: uncertain

38. The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial. Full Text available with Trip Pro

, consisting of a 12-week anti-inflammatory diet program, or control group. Outcome measures were assessed at baseline, 1 month, and 3 months and consisted of measures of motor nerve conduction velocity (NCV) and amplitude as well as markers of inflammation as assessed by various pro- and anti-inflammatory cytokines. Results: Despite a significant reduction in inflammation in the treatment group, 2-way repeated measures analysis of variance (ANOVA) showed no significant Group × Time interaction for motor (...) The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial. Objective: To examine the potential influence of chronic inflammation on peripheral motor nerve function in vivo following spinal cord injury (SCI). Methods: This study was part of a randomized, parallel-group, controlled clinical trial. The study included 20 participants with varying levels and severities of SCI randomized (3:2) to either a treatment group

2018 Topics in spinal cord injury rehabilitation Controlled trial quality: uncertain

39. Multiparity affects conduction properties of pelvic floor nerves in rabbits Full Text available with Trip Pro

-matched nulliparous and multiparous animals and associated to the histological characteristics of myelinated axons from the Bsn and Pcn nerves. The extensor digitorum longus nerve (EDLn) was used as negative control. Data were analyzed with unpaired two-tailed Student's t test or Mann-Whitney U test to determine significant differences between groups.The onset and peak latencies, duration, and conduction velocity of the motor fibers in these pelvic nerves were not significantly different between (...) Multiparity affects conduction properties of pelvic floor nerves in rabbits Women often develop pelvic floor dysfunction due to damage to the pelvic musculature during childbirth; however, the effect on pelvic floor nerves function is less understood. This study used adult rabbits to evaluate the electrophysiological and histological characteristics of the bulbospongiosus (Bsn) and pubococcygeus nerves (Pcn) in multiparity.Compound nerve action potentials (CNAP) were compared between age

2018 Brain and behavior

40. Normative Ulnar Nerve Conduction Study: Comparison of Two Measurement Methods Full Text available with Trip Pro

of motor conduction velocity of FDI and ADM at forearm and across the elbow among the normal population.In this cross-sectional study, healthy participants were enrolled in the study. Ulnar nerve motor nerve conduction velocity (MNCV) was recorded from the ADM and the FDI at forearm and across the elbow. Mean MNCV of the ulnar nerve recorded from ADM and FDI was compared. In addition, MNCV of the ulnar nerve measured at the forearm and across the elbow was compared also.During this study, 165 healthy (...) Normative Ulnar Nerve Conduction Study: Comparison of Two Measurement Methods Given the high prevalence rate of ulnar neuropathy and importance of its proper management, to have a baseline information about the normative value of motor nerve conduction of first dorsal interosseous (FDI) muscle and abductor digiti minimi muscle (ADM) and their differences as well as their relation with different demographic characteristics of our population, we aimed to determine and compare the mean value

2018 Advanced biomedical research

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