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Nerve Conduction Velocity

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1. Nerve conduction velocity is negatively associated with intima-media thickness and brachial-ankle pulse wave velocity in men with type 2 diabetes mellitus. (PubMed)

Nerve conduction velocity is negatively associated with intima-media thickness and brachial-ankle pulse wave velocity in men with type 2 diabetes mellitus. Previous studies suggest that the presence of diabetic peripheral polyneuropathy (DPN) is associated with atherosclerotic diseases; however, little is known about the relationship between diabetic nerve conduction velocity (NCV) versus arterial stiffness and atherosclerosis parameters.The subjects in this study were 292 men with type 2 (...) diabetes mellitus (T2DM). All subjects underwent NCV examination at median and tibial nerves as motor nerve (MCV) as well as median and sural nerves as sensory nerve (SCV). Brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (IMT) were evaluated as arterial stiffness and atherosclerosis parameters.Pearson's correlation coefficient showed that NCV at all sites negatively correlated with baPWV, maximal and mean IMT (IMT-Max and IMT-Mean), and plaque score (all p values p<0.01

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2018 PLoS ONE

2. Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model. (PubMed)

Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model. Down syndrome (DS) is a genetic disorder caused by presence of extra copy of human chromosome 21. It is characterised by several clinical phenotypes. Motor dysfunction due to hypotonia is commonly seen in individuals with DS and its etiology is yet unknown. Ts1Cje, which has a partial trisomy (Mmu16) homologous to Hsa21, is well reported to exhibit (...) to the Ts1Cje mice. Also, the WT mice performed significantly (P<0.05) better than the Ts1Cje mice in the latency to maintain a coordinated motor movement against the rotating rod. Adult Ts1Cje mice exhibited significantly (P<0.001) lower nerve conduction velocity compared with their aged matched WT mice. Further analysis showed a significantly (P<0.001) higher population of type I fibres in WT compared to Ts1Cje mice. Also, there was significantly (P<0.01) higher population of COX deficient fibres

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2018 PLoS ONE

3. Ultrasound and EMG–NCV study (electromyography and nerve conduction velocity) correlation in diagnosis of nerve pathologies (PubMed)

Ultrasound and EMG–NCV study (electromyography and nerve conduction velocity) correlation in diagnosis of nerve pathologies Nerve disorders are commonly encountered in clinical practice. Ultrasonography (USG) is a useful modality in the evaluation of most of the peripheral and superficial pathologies amenable to penetration by ultrasound. The primary objective is to study the USG findings of various peripheral nerve pathologies and to correlate them with electrophysiological (EMG-NCV (...) ) findings.42 patients referred with suspicion of peripheral nervous system affection were evaluated with USG along with EMG-NCV. After reviewing detailed anatomy of the region, the affected nerve was visualized along the major neurovascular bundle or at a known anatomical landmark with a high-frequency (9-20 MHz) linear/hockey stick transducer.The USG parameters, namely loss of fibrillary pattern, hypoechogenicity and nerve thickening, showed significant p value (p < 0.05) on the tests of significance

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2017 Journal of ultrasound

4. Aldose reductase inhibitor ranirestat significantly improves nerve conduction velocity in diabetic polyneuropathy: A randomized double-blind placebo-controlled study in Japan. (PubMed)

Aldose reductase inhibitor ranirestat significantly improves nerve conduction velocity in diabetic polyneuropathy: A randomized double-blind placebo-controlled study in Japan. Diabetic polyneuropathy is one of the most frequent diabetic complications, and impairs patients' quality of life. We evaluated the efficacy and safety of ranirestat (40 mg/day) in patients with diabetic polyneuropathy.This was a multicenter, placebo-controlled, randomized double-blind, parallel-group, phase III study (...) in which 557 patients were randomly assigned to either the ranirestat or placebo group and assessed for 52 weeks. The co-primary end-points were the changes in tibial motor nerve conduction velocity and total modified Toronto Clinical Neuropathy Score as a measure of clinical symptoms.There was a significant increase in tibial motor nerve conduction velocity in the ranirestat group compared with the placebo group. The difference between groups in the change at last observation was 0.52 m/s (P = 0.021

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2018 Journal of Diabetes Investigation

5. Fasudil combined with methylcobalamin or lipoic acid can improve the nerve conduction velocity in patients with diabetic peripheral neuropathy: A meta-analysis. (PubMed)

Fasudil combined with methylcobalamin or lipoic acid can improve the nerve conduction velocity in patients with diabetic peripheral neuropathy: A meta-analysis. Fasudil (F) plus methylcobalamin (M) or lipoic acid (L) treatment has been suggested as a therapeutic approach for diabetic peripheral neuropathy (DPN) in numerous studies. However, the effect of the combined use still remains dubious.The aim of this report was to evaluate the efficacy of F plus M or L (F + M or F + L) for the treatment (...) of DPN compared with that of M or L monotherapy, respectively, in order to provide the basis and reference for clinical rational drug use.Randomized controlled trials (RCTs) of F for DPN published up to September 2017 were searched. Relative risk (RR), mean difference (MD), and 95% confidence interval (CI) were calculated and heterogeneity was assessed with the I test. Sensitivity analyses were also performed. The outcomes measured were as follows: the clinical efficacy, median motor nerve conduction

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2018 Medicine

6. Investigation of the Effect of Hypnotic Anesthesia on Nerve Conduction Velocity (NCV) (PubMed)

Investigation of the Effect of Hypnotic Anesthesia on Nerve Conduction Velocity (NCV) Hypnosis is a psychological method used for treatment of different types of disorders and illnesses. This technique is also used in surgical interventions. Many studies proved the efficacy of hypnosis in medical treatment. However, the mechanism of hypnosis is unclear for scientists. To find out if the peripheral nervous system has a role in hypnotic anesthesia, we aimed to investigate the effect of hypnotic (...) anesthesia on nerve conduction velocity (NCV).In this study, healthy volunteers with high hypnotizability entered the study. First, The NCV test was performed in both hands of participants and then they all underwent hypnosis. Hypnotic anesthesia was induced in the right hand of all subjects followed by painful stimuli in their hand by vascular clasping. Then, the NCV test was repeated in both hands again. Data were analyzed by SPSS version16.The group study consisted of 13 (65%) women and 7 (35%) men

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2018 Anesthesiology and pain medicine

7. The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy (PubMed)

The Relationship between Peripheral Nerve Conduction Velocity and Ophthalmological Findings in Type 2 Diabetes Patients with Early Diabetic Retinopathy Nerve conduction velocity (NCV) is an indicator of neuronal damage in the distal segment of the peripheral nerves. Here, we determined the association between NCV and other systemic and ocular clinical findings, in type 2 diabetes patients with early diabetic retinopathy (DR).This study included 42 eyes of 42 type 2 diabetes patients (median age (...) : 54 years) with no DR or with mild nonproliferative DR. Standard statistical techniques were used to determine associations between clinical findings.Sural sensory conduction velocity (SCV) and tibial motor conduction velocity (MCV) were significantly lower in mild nonproliferative DR patients than patients with no DR (P = 0.008 and P = 0.01, resp.). Furthermore, logistic regression analyses revealed that sural SCV and tibial MCV were independent factors contributing to the presence of mild

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2018 Journal of ophthalmology

8. Gender, side to side and BMI differences in long thoracic nerve conduction velocity: A novel technique (PubMed)

Gender, side to side and BMI differences in long thoracic nerve conduction velocity: A novel technique The purpose of this study was to describe a new technique to record long thoracic nerve conduction velocity through the axilla as well as to assist in establishing normative values for latency and amplitude of the long thoracic nerve and to evaluate side to side, gender and BMI differences.26 healthy subjects (12 males/14 females) participated in the study with data collected bilaterally (...) distal latency values are not significantly different from those reported previously, however long thoracic nerve conduction velocity has not been described before and would be an appropriate way to monitor velocity through the proximal portions of the brachial plexus. Men who qualified as overweight with a BMI greater than 25 demonstrated a larger amplitude when compared with average weight men and women. In contrast women with BMI greater than 25 demonstrated a much smaller amplitude when compared

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2018 Clinical Neurophysiology Practice

9. Islet cell transplantation improves nerve conduction velocity in type 1 diabetes compared with intensive medical therapy over six years. (PubMed)

Islet cell transplantation improves nerve conduction velocity in type 1 diabetes compared with intensive medical therapy over six years. Neuropathy is a common diabetic complication that can result in significant disability. Few treatment options exist to reverse this process.We conducted a one-way crossover cohort study comparing intensive medical treatment and islet cell transplantation for type 1 diabetes on the change in nerve conduction velocity over six years.For subjects with some (...) neuropathy at baseline (Z score below -1), nerve conduction velocity significantly improved post-transplant (slope (0.073±0.042) while it worsened in medically treated patients (-0.136±0.081) (p<.05).Islet cell transplantation improves nerve conduction velocity and could be further investigated as a treatment for neuropathy in type 1 diabetes.Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

2017 Diabetes research and clinical practice

10. Tai Chi with mental imagery theory improves soleus H-reflex and nerve conduction velocity in patients with type 2 diabetes. (PubMed)

Tai Chi with mental imagery theory improves soleus H-reflex and nerve conduction velocity in patients with type 2 diabetes. Diabetes is a disease that leads to damage to the peripheral nerves which may eventually cause balance instability. The purpose of this study was to determine the effect of 8 weeks of Tai Chi (TC) training combined with mental imagery (MI) on soleus H-reflex and nerve conduction velocity (NCV) of the sural and superficial peroneal nerves in people with diabetes.Quasi (...) the intervention (p<0.01). In the H-reflex, there was a significant increase in amplitude (μV) after completing 8 weeks of TC exercise (p=0.02). In the sural nerve, the velocity (p=0.01), amplitude (p=0.01), and latency (p=0.01) were significantly improved between pre and post-test. In the superficial peroneal nerve, significant improvements were observed in (p=0.02) and latency (p=0.01), but not in amplitude (μV) (p>0.05).Combining TC intervention with MI theory showed an improvement in the H-reflex and NCV

2017 Complementary Therapies In Medicine

11. Changes of median nerve conduction velocity in rayon manufacturing workers: A 6-year cohort study (PubMed)

Changes of median nerve conduction velocity in rayon manufacturing workers: A 6-year cohort study We conducted a 6-year cohort study to evaluate the relationship between carbon disulfide (CS2) exposure and reductions in the motor and sensory nerve conduction velocity (MCV and SCV) of the median nerve.Study subjects at baseline included 432 exposed workers and 402 unexposed workers. Among the exposed workers, 145 workers terminated CS2 exposure during the follow-up period (ex-exposed workers

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2017 Journal of occupational health

12. The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus (PubMed)

The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus This study aims to establish the corneal nerve fiber (CNF) morphological alterations in a large cohort of type 2 diabetic patients and to investigate the association between the bead size, a novel parameter representing composite of accumulated mitochondria, glycogen particles, and vesicles (...) . The HbA1c levels were tightly associated with the bead size, which was inversely related to the motor and sensory nerve conduction velocity (NCV) and to the distal latency period of the median nerve positively. The CNF density and length positively correlated with the NCV and amplitude. The hyperglycemia-induced expansion of beads in CNF might be a predictor of slow NCV in peripheral nerves in type 2 diabetic patients.

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2016 Journal of diabetes research

13. Effect of pioglitazone on nerve conduction velocity of the median nerve in the carpal tunnel in type 2 diabetes patients (PubMed)

Effect of pioglitazone on nerve conduction velocity of the median nerve in the carpal tunnel in type 2 diabetes patients To evaluate the impact of pioglitazone pharmacotherapy in median nerve electrophysiology in the carpal tunnel among type 2 diabetes patients.The study was executed in patients with type 2 diabetes, treated with oral drugs, categorized under pioglitazone or non-pioglitazone group (14 in each group), and who received electrophysiological evaluation by nerve conduction velocity (...) at baseline and 3 mo.At 3 mo, pioglitazone-category had inferior amplitude in sensory median nerve [8.5 interquartile range (IQR) = 6.5 to 11.5) vs non-pioglitazone 14.5 (IQR 10.5 to 18.75)] (P = 0.002). Non-pioglitazone category displayed amelioration in amplitude in the sensory median nerve [baseline 13 (IQR = 9 to 16.25) vs 3 mo 8.5 (IQR = 6.5 to 11.5)] (P = 0.01) and amplitude in motor median nerve [baseline 9 (IQR = 4.75 to 11) vs 3 mo 6.75 (IQR = 4.75 to 10.25)] (P = 0.049); and deterioration

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2016 World journal of diabetes

14. Normal Motor and Sensory Nerve Conduction Velocity of Radial Nerve in Young Adult Medical Students (PubMed)

Normal Motor and Sensory Nerve Conduction Velocity of Radial Nerve in Young Adult Medical Students Normal nerve conduction velocity of radial nerve is essential for differential diagnosis of various type of radial neuropathies, C7 radiculopathy and nerve lesion.To study normal motor and sensory nerve conduction velocity of radial nerve in young adult medical students.Fifty medical students of either sex from first year, aged between 17- 20 year, were recruited for this nerve conduction study (...) of radial nerve using surface electrode. Motor Nerve Conduction Velocity (MNCV) and Sensory Nerve Conduction Velocity (SNCV) of radial nerve of both hand were taken out and analysed for statistical significance and standard deviation.The mean Motor Latency (ML) in right and left hand were 8.11 msec and 8.01msec respectively, Amplitude (A) 9.08mv and 8.65mv respectively and MNCV was 66.81m/sec and 67.05m/sec respectively. The SNCV were 51.41 m/sec and 51.48m/sec in the right and left hand

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2016 Journal of clinical and diagnostic research : JCDR

15. Difference in normal limit values of nerve conduction parameters between Westerners and Japanese people might need to be considered when diagnosing diabetic polyneuropathy using a Point‐of‐Care Sural Nerve Conduction Device (NC‐stat®/DPNCheck™) (PubMed)

Difference in normal limit values of nerve conduction parameters between Westerners and Japanese people might need to be considered when diagnosing diabetic polyneuropathy using a Point‐of‐Care Sural Nerve Conduction Device (NC‐stat®/DPNCheck™) Studies on a novel point-of-care device for nerve conduction study called DPNCheck have been limited to Westerners. We aimed to clarify Japanese normal limits of nerve action potential amplitude (Amp) and conduction velocity by DPNCheck (...) patients, 'probable DSPN' was diagnosed and nerve conduction abnormalities (NCA1: one or more abnormalities, and NCA2: two abnormalities in Amp and conduction velocity) were determined. Validity of NCAs to identify 'probable DSPN' was evaluated by determining sensitivity, specificity, reproducibility (kappa-coefficient) and the area under the curve of receiver operating characteristic curves.For investigation I, JRF was different from USRF, and normal limits by JRF were higher than that of USRF

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2018 Journal of Diabetes Investigation

16. Effect of high-frequency repetitive transcranial magnetic stimulation on motor cortical excitability and sensory nerve conduction velocity in subacute-stage incomplete spinal cord injury patients (PubMed)

Effect of high-frequency repetitive transcranial magnetic stimulation on motor cortical excitability and sensory nerve conduction velocity in subacute-stage incomplete spinal cord injury patients [Purpose] The aim of the present study was to determine whether repetitive transcranial magnetic stimulation can improve sensory recovery of the lower extremities in subacute-stage spinal cord injury patients. [Subjects and Methods] This study was conducted on 20 subjects with diagnosed paraplegia due (...) transcranial magnetic stimulation and conventional rehabilitation therapy. Participants in both groups received therapy five days per week for six-weeks. Latency, amplitude, and sensory nerve conduction velocity were assessed before and after the six week therapy period. [Results] A significant intergroup difference was observed for posttreatment velocity gains, but no significant intergroup difference was observed for amplitude or latency. [Conclusion] repetitive transcranial magnetic stimulation may

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2016 Journal of physical therapy science

17. NERVE CONDUCTION VELOCITY IN CMT1A: WHAT ELSE CAN WE TELL (PubMed)

NERVE CONDUCTION VELOCITY IN CMT1A: WHAT ELSE CAN WE TELL Charcot-Marie-Tooth disease (CMT) type 1A is characterized by uniformly reduced nerve conduction velocity (NCV) that is fully penetrant since the first years of life, remains fairly stable through the life and does not correlate with disability whereas compound muscular action potential (CMAP) amplitude does. The aim of the present study was to analyze the large amount of electrophysiological data collected in the ascorbic acid trial (...) in Italy and the UK (CMT-TRIAAL/CMT-TRAUK) and to use these data to gain insights into the pathophysiology of NCV in CMT1A.Baseline electrophysiological data from 271 patients were analysed. Electrophysiological recordings were taken from the motor ulnar, median and peroneal nerves and the sensory ulnar nerve. Distal motor latency (DML), motor (MNCV) and sensory (SNCV) nerve conduction velocity, and amplitudes of CMAPs and sensory action potentials were assessed. Electrophysiological findings were

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2016 European Journal of Neurology

18. Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs. (PubMed)

Motor nerve conduction velocity is affected in segmental vitiligo lesional limbs. To evaluate the effects of segmental vitiligo (SV) on nerve conduction velocity (NCV) in different nerves, we compared the patient's lesional side of their body to the contralateral normal side. The 106 participants were selected from outpatients visiting the dermatological clinics of Huashan Hospital, Fudan University, from November 2011 to March 2014. NCVs were measured on the limbs and the face, including both (...) motor and sensory nerves. The parameters for NCVs included motor nerve conduction velocity (MCV) and its distal conduction latency, sensory nerve conduction velocity, sensory nerve action potentials amplitude, and compound muscle action potential amplitude. MCV on the limbs was compromised by SV state, which was significantly slower on the lesional side of the body compared with the normal contralateral side (P = 0.006). Furthermore, SV at the stable stage significantly impaired MCV compared

2016 International Journal of Dermatology

19. Nerve Conduction Velocity

Nerve Conduction Velocity Nerve Conduction Velocity Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Nerve Conduction Velocity Nerve (...) Conduction Velocity Aka: Nerve Conduction Velocity , Nerve Conduction Studies , Nerve Conduction Study II. Indication Tests integrity of peripheral nerve myelin and axon Differentiates causes Distribution (single nerve or diffuse involvement) See Causes (e.g. ) (e.g. ) Component of nerve involved (see below) al or axonal EMG slowed out of proportion to nerve conduction Demyelinating or infiltrative Nerve conduction slowed out of proportion to EMG III. Interpretation Axonal (EMG slowed more than NCS

2018 FP Notebook

20. Motor Nerve Conduction Velocity In Postmenopausal Women with Peripheral Neuropathy (PubMed)

Motor Nerve Conduction Velocity In Postmenopausal Women with Peripheral Neuropathy The post-menopausal phase is characterized by a decline in the serum oestrogen and progesterone levels. This phase is also associated with higher incidence of peripheral neuropathy.To explore the relationship between the peripheral motor nerve status and serum oestrogen and progesterone levels through assessment of Motor Nerve Conduction Velocity (MNCV) in post-menopausal women with peripheral neuropathy.This (...) cross-sectional study was conducted at Jawaharlal Nehru Medical College during 2011-2013. The study included 30 post-menopausal women with peripheral neuropathy (age: 51.4±7.9) and 30 post-menopausal women without peripheral neuropathy (control) (age: 52.5±4.9). They were compared for MNCV in median, ulnar and common peroneal nerves and serum levels of oestrogen and progesterone estimated through enzyme immunoassays. To study the relationship between hormone levels and MNCV, a stepwise linear

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2016 Journal of clinical and diagnostic research : JCDR

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