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Neonatal Teeth

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121. Clinico-radiologic features of molar-incisor malformation in a case series of 38 patients: A retrospective observational study. (Full text)

%), and endodontic-periodontal lesion (28.9%). The medical histories of the patients with MIM indicate that almost all (94.7%) were hospitalized due to problems during the neonatal period. MIM may cause various dental problems, such as periapical and periodontal abscess and early loss of the affected teeth. The early diagnosis of MIM on radiographs and appropriate treatment will contribute to a favorable prognosis, especially for young and adolescent patients.

2019 Medicine PubMed abstract

122. Candida - oral

How common is it? Candida is part of the normal commensal flora in the human digestive tract. The oral carriage is reported to be [ ]: 30–45% in healthy adults. 45% in neonates. 45–65% in healthy children. Oral candidiasis is the most common human opportunistic fungal infection of the oral cavity [ ; ; ] . However, it is rare in healthy adults and older children, and tends to mostly affect [ ; ; ]: Young children and infants (due to immature immunity) — it affects about 5% of newborns, increasing (...) suspension (unlicensed for use in neonates). See the prescribing information sections on and for information on prescribing these treatments, including contraindications, cautions, adverse effects, and possible drug interactions. Give appropriate lifestyle advice to aid healing and prevent recurrence. In particular: Advise on good dental hygiene. If the child is using an inhaled corticosteroid, advise the following: good inhaler technique; rinsing the mouth with water (or cleaning the teeth) after

2017 NICE Clinical Knowledge Summaries

123. Bexsero (Neisseria meningitidis)

is submitted under Article 3(1) of Regulation (EC) No 726/2004, i.e. the centralised procedure is mandatory (Biotech medicinal product). In accordance with Regulation (EC) No 1901/2006, the applicant submitted in March 2008 an application for Paediatric Investigational Plan (PIP) for Multi-Component Meningococcal B Vaccine with a request of waiver in neonates/infants less than 8 weeks of age and deferral for some studies contained in the paediatric investigational plan as per final PDCO Opinion on the PIP

2012 European Medicines Agency - EPARs

124. Inlyta - axitinib

-glucuronidation at the NH position of axitinib disrupted a key hydrogen bond and significantly compromised an appropriate fit in the ATP binding site. The in vivo effects of anti-angiogenesis of axitinib were investigated in retinal tissues of rats and xenograft tumours in mice. Newborn rats were treated with two IP injections of axitinib hydrochloride of 10 or 30 mg/kg before the retinal tissues were collected and processed. Immunoprecipitation and Western blot (IP/IB) experiments were performed

2012 European Medicines Agency - EPARs

125. Elelyso - taliglucerase alfa

is difficult. In the recent classification adopted by treating physicians the GD population is classified according to the absence (non-neuropathic GD [NNGD]) or presence (neuropathic GD [NGD]) of complex neurological symptoms. The latter group is further subdivided into “acute” or “chronic” neuropathic disease. Acute neuropathic disease (“acute NGD”) appears in newborns ( = 1 year) with a very severe neurological presentation that results in the death of the patient within the first 2 years of age

2012 European Medicines Agency - EPARs

126. Vitamin D supplementation: Recommendations for Canadian mothers and infants

may also have their beginnings in fetal or early newborn life. Studies suggest that infants of mothers who are vitamin D- or calcium-deficient during pregnancy may be at risk for enamel defects in primary and permanent teeth in spite of adequate supplementation later (evidence level II-3). Aboriginal communities with a high incidence of vitamin D deficiency have an associated high prevalence of caries , although no studies of cause and effect have been carried out. The purpose of the present (...) . Enamel defects in primary and permanent teeth of children born prematurely. J Oral Pathol Med 2000;29:403-9. Purvis RJ, Barrie WJ, MacKay GS, Wilkinson EM, Cockburn F, Belton NR. Enamel hypoplasia of the teeth associated with neonatal tetany: A manifestation of maternal vitamin-D deficiency. Lancet 1973;2:811-4. Smith PJ, Moffatt ME. Baby-bottle tooth decay: Are we on the right track? Int J Circumpolar Health 1998;57(Suppl 1):155-62. Standing Committee on the Scientific Evaluation of Dietary

2012 Canadian Paediatric Society

127. Recommendations for the use of pacifiers

of sudden infant death syndrome in an urban population: The Chicago Infant Mortality study. Pediatrics 2003;111:1207-14. Canadian Paediatric Society, Fetus and Newborn Committee and American Academy of Pediatrics, Committee on Fetus and Newborn and Section on Anesthesiology and Section on Surgery. Prevention and management of pain and stress in the neonate. Paediatr Child Health 2000;5:31-8. Stevens B, Yamada J, Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures (Cochrane (...) was counselled to avoid pacifiers. They found a significant difference in pacifier avoidance (38.6% versus 16.0%) but no difference in rates of weaning before three months of age (18.9% versus 18.3%). In the observational analyses, however, pacifier use was strongly associated with early weaning. They concluded that pacifier use may be a marker of breastfeeding difficulties or reduced motivation to breastfeed, rather than a true cause of early weaning. Another study randomly assigned healthy newborns

2012 Canadian Paediatric Society

128. Mouth Guard Use in the Second Stage of Labor

outcomes. Condition or disease Intervention/treatment Phase Dystocia; Fetal Labor Long Cesarean Section, Affecting Fetus or Newborn Device: Mouth Guard Not Applicable Detailed Description: Optimizing the second stage of labor is important for positive maternal and neonatal outcomes. Dystocia of labor refers to a lack of progress of labor for any reason, and it is the most common indication for cesarean delivery in nulliparous women and the second most common indication for cesarean delivery (...) increases in complications in both mother and infant when pushing was prolonged, including uterine infection, postpartum hemorrhage, more extensive vaginal tearing, shoulder dystocia, 5 minute Apgar score less than 4, infant admission to Neonatal Intensive Care Unit and neonatal infections. Therefore, the challenge is to consider alternative practices in order to maximize a mother's chance of a vaginal delivery and minimize these associated risks to both mother and baby. Mouth guards are used primarily

2018 Clinical Trials

129. Early-life events and developmental defects of enamel in the primary dentition. (Abstract)

Early-life events and developmental defects of enamel in the primary dentition. To investigate the occurrence of developmental defects of enamel (DDE) in the primary teeth of children aged 24-36 months and their association with early-life events.This study was undertaken with children aged 24-36 months in Pelotas, Southern Brazil. Information on demographic and socioeconomic characteristics, events occurring during pregnancy and neonatal events was collected previously. In this study

2018 Community Dentistry and Oral Epidemiology

130. Presence of Enamel Fluorosis in Libyan Children

: Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3). A considerable amount of evidence has been reported over the years, which has shown that presence of fluoride ions at up to one part per million in public water supply has reduced the prevalence of teeth decayed with minimal chance of dental fluorosis. The WHO recognized these facts by its resolution in 1969 4 and 1975 5, which stated that water (...) fluoridation, where applicable, should be the cornerstone of any national policy of caries prevention Condition or disease Dental Fluorosis Detailed Description: The optimal concentration is defined as that which gives maximal protection against dental caries, with minimal clinically observable dental fluorosis (Dunning 7). This level is determined according to the climate and the resultant drinking habits (Newborn 6). Cawson 1 stated that mottling of enamel is the most frequently seen and most reliable

2018 Clinical Trials

131. Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome. (Full text)

Bi-allelic POLR3A Loss-of-Function Variants Cause Autosomal-Recessive Wiedemann-Rautenstrauch Syndrome. Wiedemann-Rautenstrauch syndrome (WRS), also known as neonatal progeroid syndrome, is a rare disorder of unknown etiology. It has been proposed to be autosomal-recessive and is characterized by variable clinical features, such as intrauterine growth restriction and poor postnatal weight gain, characteristic facial features (triangular appearance to the face, convex nasal profile or pinched (...) nose, and small mouth), widened fontanelles, pseudohydrocephalus, prominent scalp veins, lipodystrophy, and teeth abnormalities. A previous report described a single WRS patient with bi-allelic truncating and splicing variants in POLR3A. Here we present seven additional infants, children, and adults with WRS and bi-allelic truncating and/or splicing variants in POLR3A. POLR3A, the largest subunit of RNA polymerase III, is a DNA-directed RNA polymerase that transcribes many small noncoding RNAs

2018 American Journal of Human Genetics PubMed abstract

132. the Effect of Prenatal Vitamins on the Tooth Structure

by (Responsible Party): Dina mounir elkady, Cairo University Study Details Study Description Go to Brief Summary: the effect of mother prenatal care on the teeth of the newborn children, if it affect the tooth structure or not Condition or disease Intervention/treatment Dental Caries Other: intervention Detailed Description: teeth lost due to normal shedding will be collected,it will be classified into mother that take pregnancy vitamins and mother that doesn't take pregnancy vitamins, the female will be from (...) the same population and from the same city to make sure that the environmental condition are almost the same .teeth will be subjected to elementary analysis to determine the different ratio of different component and if there is any change between the two group Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 50 participants Observational Model: Cohort Time Perspective: Retrospective Official Title: the Effect of Prenatal Vitamins on the Children

2018 Clinical Trials

133. Oral Pathology in Forensic Investigation (Full text)

morphology of teeth, and deoxyribonucleic acid profiling from teeth. This subdiscipline is also utilized for age estimation studies which include Gustafson's method, incremental lines of Retzius, perikymata, natal line formation in teeth, neonatal line, racemization of collagen in dentin, cemental incremental lines, thickness of the cementum, and translucency of dentin. Even though the expertise of an oral pathologist is not taken in forensic investigations, this paper aims to discuss the role of oral

2018 Journal of International Society of Preventive & Community Dentistry PubMed abstract

134. Lessons learnt in recruiting disadvantaged families to a birth cohort study (Full text)

nurses found the early phase of parenting was an overwhelming stage for parents as they are pre-occupied with more immediate issues such as settling and feeding a newborn. They highlighted some key time-points such as during pregnancy and/or around the time of infant teething may be more appropriate for recruiting families to dental research projects. However, they found it easier to secure the family's attention by offering incentives, gifts and invitations for free oral health services. The use

2018 BMC nursing PubMed abstract

135. Quality Improvement Guidelines for Pediatric Gastrostomy and Gastrojejunostomy Tube Placement

in children can lead to cholestatic liver disease and liver failure requiring liver transplantation (9,14,15). For all these reasons, placement of a percutaneousGtubehasbecomeacommonlyperformedprocedure.In adults, the most commonly used arti?cial feeding route is via a gastrostomy with feeds delivered directly into the stomach (8). To receive a G tube, a child must have normal or near-normal gastric and small bowel motility, and gastric anatomy must be adequate (8). At least in the newborn, transpyloric (...) or deep sedation for early detection of microalveolar hypoventilation and prevention of hypoxemia (43,44). It is also essential that sedation providers properly recognize patients at high risk for sedation complications (39), including newborns and infants, and patients with: Respiratory impairment Cardiovascular disease Symptomatic gastroesophageal re?ux or poor gastric emptying Restricted hepatic and renal clearance Neuromuscular and metabolic diseases Neurodegenerative diseases Craniofacial

2014 Society of Interventional Radiology

136. Diagnosis and management of von Willebrand disease

in a obstetric unit with close collaboration between haematology, obstetric, anaesthetic and neonatal teams and access to 24-h moni- toring of FVIII-VWF (2C). ? The delivery of women with type 1 VWD can be man- aged as normal when VWF:RCo activity is >05 iu/ml by 34–36 weeks gestation (1C). ? Vaginal delivery or Caesarean section can be performed when VWF:RCo activity is maintained >05 iu/ml and platelet count maintained >503 10 9 /l (2C). ? Neuraxial anaesthesia is not recommended in women with type 2 (...) & Haemostasis, 4, 2103–2114. Sakurai, Y., Shima, M., Imai, Y., Omura, S., Kirita, T. & Yoshioka, A. (2006) Successful use of recombinant factor VIII devoid of von Wille- brand factor during multiple teeth extractions in a patient with type 3 von Willebrand disease. Blood Coagulation & Fibrinolysis, 17, 151–154. Sanchez-Luceros, A., Meschengieser, S.S., Mar- chese, C., Votta, R., Casais, P., Woods, A.I., Nadal, M.V., Salviu, M.J. & Lazzari, M.A. (2003) Factor VIII and von Willebrand factor changes during

2014 United Kingdom Haemophilia Centre Doctors' Organisation

137. The use of bisphosphonates in children - review of the literature guidelines for dental management

in the growing child may in?uence development of the dentition. Resorption of primary teeth roots is required for their exfoliation, and resorption of bone is critical to tooth eruption. The potential effect that bisphosphonates may have on these processes is cur- rently unknown. While various consensus guidelines and recommen- dations pertaining to the dental management of patients treated with bisphosphonates have been pub- lished, 3,5–11 none of these speci?cally address paediat- ric patients. This has (...) studies, no complications were identi- ?ed. Tooth eruption and exfoliation Bone resorption is critical to tooth eruption. For per- manent teeth, eruption requires resorption of both the roots of the deciduous predecessors, as well as bone coronal to the developing tooth. Given the action of bisphosphonates on inhibition of bone resorption, the potential for these agents to delay tooth eruption is of interest. In the rat model, delayed tooth eruption has been found following administration

2014 Clinical Practice Guidelines Portal

138. Royal Flying Doctor Service Western Operations Clinical manual part 1.Clinical guidelines

breaths continue with chest compressions. ? In children ALS providers should perform CPR with a ratio of 15:2 (Neonates less than a few hours old use neonate algorithm). ATTACH DEFIBRILLATOR ASAP THEN ALS ALGORITHM No No D A S R B D C RFDS Western Operations Version 6.0 Clinical Manual Issue Date: January 2013 Part 1 - Clinical Guidelines Section 1 Page 2 Life Support 1.2 Newborn Life Support Flow Chart If more than a few hours old use paediatric algorithm. Figure 2. Newborn Life Support Flow Chart (...) This is a controlled document. Ensure you are using the latest version. Filename: G:\HEALTH\MEDICAL\CLINICAL MANUAL\PART 1 – CLINICAL GUIDELINES – JANUARY 2013 Savedate: 20/12/2012 16:47 RFDS Western Operations Version 6.0 Clinical Manual Issue Date: January 2013 Part 1 - Clinical Guidelines Table of Contents Part 1 - Clinical Guidelines Table of Contents 1 LIFE SUPPORT 1 1.1 Basic Life Support Flow Chart 1 1.2 Newborn Life Support Flow Chart 2 1.3 Advanced Life Support (Adult) 3 1.4 Advance Life Support

2014 Clinical Practice Guidelines Portal

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