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Neonatal Teeth

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102. Persistent Pain with Breastfeeding

are pre- mature, have low oral tone, and re?ux/aspiration or congenital anomalies that may be at risk for disor- ganized suckling. 12 (III) Evaluation of the infant for dif?culty coordinating sucking and swallowing may be indicated. B Ankyloglossia (tongue-tie), recognized in 0.02– 10.7% of newborns, involves the restriction of ton- gue movement (projection) beyond the lower gum 13 due to an abnormally short or thickened lingual frenulum. Poor tongue movement may lead to dif- ?culty attaining a deep (...) clavicle fractures, torticollis, head/neck or facial trauma, mandibular asymmetry, 16 oral defensiveness or aversion (e.g., infantsforce-fedwithridgednipples[teats]),tonicbite re?ex, nasal congestion, a response to an overactive milk ejection re?ex, and teething. (III) 2. Breast pump trauma/misuse Because of the widespread use of breast pumps in many countries and the variability of consumer edu- cation, literacy, and support, there is signi?cant po- tential for harm from breast pump use. In a survey

2016 Academy of Breastfeeding Medicine

103. Perinatal death and exposure to dental amalgam fillings during pregnancy in the population-based MoBa cohort. Full Text available with Trip Pro

with dental amalgam.Data on perinatal death (stillbirth ≥ 22 weeks plus early neonatal death 0-7 days after birth) were obtained from the Medical Birth Registry of Norway.The absolute risk of perinatal death ranged from 0.20% in women with no amalgam-filled teeth to 0.67% in women with 13 or more teeth filled with amalgam. Analyses including the number of teeth filled with amalgam as a continuous variable indicated an increased risk of perinatal death by increasing number of teeth filled with dental (...) Perinatal death and exposure to dental amalgam fillings during pregnancy in the population-based MoBa cohort. The aim was to gain knowledge regarding the risk of perinatal death related to exposure to dental amalgam fillings in the mother.Population-based observational cohort study.The Norwegian Mother and Child Cohort Study, a Norwegian birth cohort of children born in 1999-2008 conducted by the Norwegian Institute of Public Health.72,038 pregnant women with data on the number of teeth filled

2018 PLoS ONE

104. Limb bone histology records birth in mammals. Full Text available with Trip Pro

non-cyclical BGMs and a stressful biological event in mammals: the moment of birth. In the present study, we histologically examine ontogenetic series of femora, tibiae and metapodia in several extant representatives of the genus Equus (E. hemionus, E. quagga and E. grevyi). Our analysis reveals the presence of a non-cyclical growth mark that is deposited around the moment of birth, analogous to the neonatal line described for teeth. We therefore refer to it as neonatal line. The presence (...) of this feature within the bone cross-section agrees with a period of growth arrest in newborn foals regulated by the endocrine system. The neonatal line is accompanied by modifications in bone tissue type and vascularization, and has been identified in all bones studied and at different ontogenetic ages. Our discovery of a non-cyclical BGM related to the moment of birth in mammals is an important step towards the histological reconstruction of life histories in extant and fossil equids.

2018 PLoS ONE

105. Specimen collection - microbiology and virology

bottles, the anaerobic culture bottle should be inoculated first and then the aerobic culture bottle, so that oxygen trapped in the syringe will not be transferred to the anaerobic bottle. The volume of blood is the most critical factor in the detection of blood stream infections. Place up to 4ml in the aerobic bottle (priority) and up to 10ml in the anaerobic bottle, but ensure that when using both bottles, the anaerobic bottle is inoculated first. For neonates, one to two millilitres of blood (...) is recommended ( ). However, the sensitivity of neonatal blood cultures is increased if more blood is cultured. Inoculation of the blood into the blood culture bottles should be performed first before inserting blood into other bottles as many of these bottles are not sterile and accidental contamination may occur. In children with suspected central venous line sepsis, blood for culture may be taken from a peripheral vein stab and also from (all lumen) of the intravascular lines to enable identification

2014 Publication 1593

106. Mouth care

( ). Foam cleaning sponges are ineffective at removing plaque ( ). Foam cleaning sponges are useful in the following situations: When a child has no teeth – moisten sponges with water ( ). When a child or young person has severe mucositis that prevents them from brushing their teeth – foam sponges can be moistened with water ( ). For palliative care situations when comfort is the only intended outcome. Mouth care packs should be disposed of once opened. In neonates these sponges may be too large (...) . smiling and grimacing. The tongue This is covered with stratified squamous epithelium for protection, from which project numerous papillae and taste buds on the upper surface. The tongue plays an important part in mastication (chewing), deglutition (swallowing), speech and taste ( ). The teeth Although the shape of teeth varies, the structure is the same and consists of: The crown – protrudes from the gum. The root – embedded in the bone. The interior of the tooth consists of a pulp cavity

2014 Publication 1593

108. Infective Endocarditis in Childhood: 2015 Update Full Text available with Trip Pro

be a factor in the risk for IE. IE in Newborn Infants In a recent multicenter review, 7.3% of cases of pediatric IE (108 of 1480) were diagnosed in the first month of life. Improved and widely available imaging technology, particularly echocardiography, and increased clinical awareness have greatly facilitated the diagnosis of IE in this patient group. The incidence of neonatal IE has increased in the past 2 decades in large measure because of the increasing use of invasive techniques to manage neonates (...) with previous cardiac surgery appear to have increased in recent years in some reports. This may be related to improved survival among children who are at risk for endocarditis, such as those with CHD (with or without surgery) and hospitalized newborn infants. Before the 1970s, 30% to 50% of US children with IE had underlying rheumatic heart disease. Because the prevalence of rheumatic heart disease has declined in developed countries, including the United States, it has now become relatively unusual

2015 American Heart Association

109. Acute Pain Management: Scientific Evidence

factors for the development of postoperative acute persistent pain. Trends Anaesth Critical Care 4: 67–70. Shipton EA (2014b) The transition of acute postoperative pain to chronic pain: Part 2 - Limiting the transition. Trends Anaesth Critical Care 4: 71–75. Vidaeff AC, Saade GR, Belfort MA (in press) Interpreting a randomized trial report: evidence-based practice for the clinician. J Matern Fetal Neonatal Med. Walsh M, Woodhouse LJ, Thomas SG, Finch E (2011) Strategies aimed at preventing chronic (...) Paediatric pain assessment 412 9.3.1 Pain assessment in neonates 413 9.3.2 Observational and behavioural measures in infants and children 414 9.3.3 Self-report in children and adolescents 415 9.3.4 Children with cognitive impairment or intellectual disability 416 9.4 Analgesic agents 421 9.4.1 Paracetamol 421 9.4.2 Nonselective NSAIDs 424 9.4.3 Coxibs 429xix CONTENTS 9.4.4 Opioids and tramadol 430 9.4.5 Ketamine 438 9.4.6 Alpha-2-delta ligands (gabapentin/pregabalin) 440 9.4.7 Alpha-2 adrenergic agonists

2015 Clinical Practice Guidelines Portal

110. Long term follow up of survivors of childhood cancer

adverse effects on uterine function or pregnancy outcomes, other than increased risk of miscarriage shortly after chemotherapy, related to damage to oocytes. 95 In contrast, abdominopelvic radiotherapy is associated with adverse effects on uterine function with increased risk of late miscarriage, prematurity, low birth weight, stillbirth, neonatal haemorrhage and postpartum haemorrhage. The effect is age related, the younger the patient at treatment the greater the adverse effect on uterine function

2013 SIGN

113. Guidelines for the treatment of malaria. Third edition

or combined with SP or artesunate; 5 | Treatment of uncomplicated P.falciparum malaria in special risk groups 50 Guidelines for the treatment of malaria 3 RD EDITIONhowever, amodiaquine use for the treatment of malaria in pregnancy has been formally documented in only > 1300 pregnancies. Use of amodiaquine in women in Ghana in the second and third trimesters of pregnancy was associated with frequent minor side- effects but not with liver toxicity, bone marrow depression or adverse neonatal outcomes (...) with falciparum malaria, although drug exposure was similar in pregnant and non-pregnant women with vivax malaria. 5 | Treatment of uncomplicated P.falciparum malaria in special risk groups 515.1.4 | LACTATING WOMEN The amounts of antimalarial drugs that enter breast milk and are consumed by breastfeeding infants are relatively small. Tetracycline is contraindicated in breastfeeding mothers because of its potential effect on infants’ bones and teeth. Pending further information on excretion in breast milk

2015 World Health Organisation Guidelines

114. National hepatitis B testing policy

and children from culturally and linguistically diverse (CALD) backgrounds, particularly those born in countries of intermediate and high HBV prevalence (see section 3.1, figure 1 ) • Aboriginal and Torres Strait Islander people. Australia has implemented a universal vaccination program for hepatitis B to reduce the risk of transmission of HBV infection. Universal neonatal vaccination commenced in all States and Territories in May 2000. State and Territory Departments of Health operated catch-up (...) for a coordinated, accessible and affordable HBV testing system that allows for: • access to appropriately resourced services for people at risk of acquiring HBV infection and for those diagnosed with HBV infection to optimise monitoring and clinical management, and to ensure timely referral to treatment; • the reduction of HBV transmission through knowledge of one’s status; • the reduction of transmission from a mother with HBV infection to her newborn; • monitoring the response to vaccination against HBV

2015 Clinical Practice Guidelines Portal

115. How best to treat UTIs in women who breastfeed?

poor feeding; amoxicillin and cephalexin may cause diarrhea; nitrofurantoin may cause diarrhea or, in infants with G6PD deficiency, hemolytic anemia; and ciprofloxacin may cause pseudomembranous colitis in infants and green teeth in neonates (SOR: C, case reports and expert opinion). URI Citation Journal of Family Practice, 63(2) 2014: 102-103. Collections hosted by hosted by

2014 Clinical Inquiries

116. Iron Deficiency Anemia in Pregnant Women: Screening and Supplementation

or stool, staining of teeth and gums, and drug interactions with other medications. Current Practice Rates of screening for iron deficiency anemia and iron supplementation in pregnant women by clinicians are not well-documented. However, based on anecdotal evidence, it is probably common. In addition, there may be other reasons to screen for anemia in pregnant women, such as to prepare for cesarean delivery or anticipated blood loss during a complicated delivery. Older data from 1988 show that 97 (...) and serum erythropoietin in 120 mothers and newborn infants. Effect of iron supplementation in normal pregnancy. Acta Obstet Gynecol Scand . 1994;73(3):200-4. 19. Ziaei S, Mehrnia M, Faghihzadeh S. Iron status markers in nonanemic pregnant women with and without iron supplementation. Int J Gynaecol Obstet . 2008;100(2):130-2. 20. Ziaei S, Norrozi M, Faghihzadeh S, Jafarbegloo E. A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome in pregnant women

2015 U.S. Preventive Services Task Force

117. Oral health status in relation to socioeconomic and behavioral factors among pregnant women: a community-based cross-sectional study. Full Text available with Trip Pro

Oral health status in relation to socioeconomic and behavioral factors among pregnant women: a community-based cross-sectional study. Oral health of women during pregnancy is an important issue. Not only it can compromise pregnancy outcomes, but also it may affect their newborn's overall health. The aim of this study was to assess the oral health status and associated factors in pregnant women.A cross-sectional study was conducted amongst 407 pregnant women in the second and third trimester (...) of pregnancy in Varamin, Iran. Oral health status was examined, and demographic, socioeconomic status and dental care behavior data were collected. Oral health indices included periodontal pocket, bleeding on probing (BOP) and decayed, missed, filled teeth (DMFT). Regression analysis of DMFT was used to study the association between demographic, dental care behaviors indicators and outcome variables using the count ratios (CR) and 95% confidence intervals (CI).The mean (SD, Standard Deviation) age

2019 BMC Oral Health

118. Clinico-radiologic features of molar-incisor malformation in a case series of 38 patients: A retrospective observational study. Full Text available with Trip Pro

%), and endodontic-periodontal lesion (28.9%). The medical histories of the patients with MIM indicate that almost all (94.7%) were hospitalized due to problems during the neonatal period. MIM may cause various dental problems, such as periapical and periodontal abscess and early loss of the affected teeth. The early diagnosis of MIM on radiographs and appropriate treatment will contribute to a favorable prognosis, especially for young and adolescent patients.

2019 Medicine

119. Candida - oral

How common is it? Candida is part of the normal commensal flora in the human digestive tract. The oral carriage is reported to be [ ]: 30–45% in healthy adults. 45% in neonates. 45–65% in healthy children. Oral candidiasis is the most common human opportunistic fungal infection of the oral cavity [ ; ; ] . However, it is rare in healthy adults and older children, and tends to mostly affect [ ; ; ]: Young children and infants (due to immature immunity) — it affects about 5% of newborns, increasing (...) suspension (unlicensed for use in neonates). See the prescribing information sections on and for information on prescribing these treatments, including contraindications, cautions, adverse effects, and possible drug interactions. Give appropriate lifestyle advice to aid healing and prevent recurrence. In particular: Advise on good dental hygiene. If the child is using an inhaled corticosteroid, advise the following: good inhaler technique; rinsing the mouth with water (or cleaning the teeth) after

2017 NICE Clinical Knowledge Summaries

120. Bexsero (Neisseria meningitidis)

is submitted under Article 3(1) of Regulation (EC) No 726/2004, i.e. the centralised procedure is mandatory (Biotech medicinal product). In accordance with Regulation (EC) No 1901/2006, the applicant submitted in March 2008 an application for Paediatric Investigational Plan (PIP) for Multi-Component Meningococcal B Vaccine with a request of waiver in neonates/infants less than 8 weeks of age and deferral for some studies contained in the paediatric investigational plan as per final PDCO Opinion on the PIP

2012 European Medicines Agency - EPARs

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