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Nasal Packing

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1. Ointments versus Nasal Packing and Cautery for the Management of Recurrent Epistaxis: Comparative Clinical Effectiveness

Ointments versus Nasal Packing and Cautery for the Management of Recurrent Epistaxis: Comparative Clinical Effectiveness Ointments versus Nasal Packing and Cautery for the Management of Recurrent Epistaxis: Comparative Clinical Effectiveness | CADTH.ca Find the information you need Ointments versus Nasal Packing and Cautery for the Management of Recurrent Epistaxis: Comparative Clinical Effectiveness Ointments versus Nasal Packing and Cautery for the Management of Recurrent Epistaxis (...) : Comparative Clinical Effectiveness Published on: September 27, 2017 Project Number: RB1139-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the comparative clinical effectiveness of ointment with nasal packing or cautery for the management and prevention of recurrent epistaxis? What is the comparative clinical effectiveness of petroleum jelly with bacteriostatic ointments for the management and prevention of recurrent epistaxis

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

2. Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs: Randomized Controlled Trial

Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs: Randomized Controlled Trial We evaluated the efficacy of topical application of the injectable form of tranexamic acid (TXA) compared with anterior nasal packing (ANP) for the treatment of epistaxis in patients taking antiplatelet drugs (aspirin, clopidogrel, or both) who presented to the emergency department (ED).A randomized, parallel-group clinical trial

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2018 EvidenceUpdates

3. Effect of Fentanyl Nasal Packing Treatment on Patients With Acute Postoperative Pain After Nasal Operation: A Randomized Double-Blind Controlled Trial. (PubMed)

Effect of Fentanyl Nasal Packing Treatment on Patients With Acute Postoperative Pain After Nasal Operation: A Randomized Double-Blind Controlled Trial. Nasal packing is an option for bleeding control after endoscopic sinus surgery and septoplasty. Although new packing materials have been developed, patients still suffer from pain and require additional analgesics treatments. In this study, a prospective, randomized, and double-blind controlled trial was designed to evaluate the effect (...) of fentanyl-soaked packing on pain after endoscopic sinus surgery and septoplasty.One hundred fifty-two patients who underwent nasal surgeries due to chronic rhinosinusitis or nasal septal deviation were enrolled in this study. At the end of operation, 50 mcg fentanyl-soaked biodegradable synthetic polyurethane foams packing Nasopore or Merocel were applied to a group of 79 patients, and saline-soaked ones were applied to another group of 73 patients. To evaluate the influence of fentanyl on postoperative

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2018 Rhinology and Laryngology

4. Efficacy of L/A Spray andL/A-soaked Nasal Packings on Postoperative Pain After Nasal Closed Reduction

Efficacy of L/A Spray andL/A-soaked Nasal Packings on Postoperative Pain After Nasal Closed Reduction Efficacy of L/A Spray andL/A-soaked Nasal Packings on Postoperative Pain After Nasal Closed Reduction - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Efficacy of L/A Spray andL/A-soaked Nasal Packings on Postoperative Pain After Nasal Closed Reduction The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03733275 Recruitment

2018 Clinical Trials

5. Fibrin tissue adhesive versus nasal packing in endoscopic nasal surgery: a systematic review and meta-analysis. (PubMed)

Fibrin tissue adhesive versus nasal packing in endoscopic nasal surgery: a systematic review and meta-analysis. It has been proposed that fibrin tissue adhesive (FTA) can act as an effective alternative to nasal packing in managing the postoperative symptoms of endoscopic nasal surgery.MEDLINE, Embase, Cochrane Library, The Cumulative Index to Nursing and Allied Health Literature and ClinicalTrials.gov were searched for randomised controlled trials comparing FTA with nasal packing in endoscopic (...) nasal surgery. The primary outcome of interest was bleeding; secondary outcomes included pain, nasal obstruction, infection, adhesions and the formation of granulation tissue. All trials underwent a risk of bias assessment, and a meta-analysis was performed using a random effects model.315 studies were found, of which four were eligible for inclusion (n = 152). Bleeding was reported in all, with the meta-analysis favouring the packing group, although this was not significant. Nasal obstruction

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2018 Rhinology

6. Prophylactic Antibiotics in Anterior Nasal Packing for Epistaxis

Prophylactic Antibiotics in Anterior Nasal Packing for Epistaxis Emergency Medicine > Journal Club > Archive > May 2014 Toggle navigation May 2014 Prophylactic Antibiotics in Anterior Nasal Packing for Epistaxis Vignette You are working in your community emergency department (ED) one winter afternoon when you encounter Mr. D. He is a 64 year old gentleman with a history of hypertension, who takes amlodipine and a daily 81 mg aspirin. He presents with one hour of continuous right-­sided (...) the patient home with a prescription for amoxicillin-­clavulanic acid. You are back working again 4 days later, when Mr. D returns to the ED. His nasal packing was removed the day prior without incident and a small area in his nasal mucosa was cauterized successfully by the ENT physician. Mr. D is presenting now with horrible diarrhea and abdominal cramping. As you leave the room and get ready to order a C. diff toxin screen for his stool, you wonder if it’s really worth putting patients with anterior

2014 Washington University Emergency Medicine Journal Club

7. Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol. (PubMed)

Novel use of tranexamic acid to reduce the need for Nasal Packing in Epistaxis (NoPac) randomised controlled trial: research protocol. Patients presenting to emergency departments (EDs) with epistaxis uncontrolled by subsequent simple first aid measures or application of topical vasoconstrictors will typically undergo anterior nasal packing. Packing is effective, but can be extremely painful and unpleasant and patients usually need hospital admission. Tranexamic acid (TXA) is a cheap, safe (...) is at 1 week by structured telephone review. The primary outcome measure is the subsequent need for anterior nasal packing in the ED. Key secondary outcomes include the need for hospital admission, blood transfusion and/or further treatment for epistaxis during the index ED attendance. Recruiting 450 patients will provide 90% power to demonstrate an absolute reduction in packing rate from 95% to 85%. An improvement of this magnitude would be of significant benefit to patients and healthcare providers

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2019 BMJ open

8. Nasal self-packing for epistaxis in Hereditary Hemorrhagic Telangiectasia increases quality of life. (PubMed)

Nasal self-packing for epistaxis in Hereditary Hemorrhagic Telangiectasia increases quality of life. Hereditary hemorrhagic telangiectasia (HHT) is characterized by recurrent epistaxis that can lead to a feeling of losing control. We assessed potential benefits and side effects of different nasal packings used by patients themselves.An online-questionnaire in English and German was used to analyze nasal self-packings.588 of the 915 respondents suffered from HHT with most of them having moderate (...) or severe epistaxis. Almost two thirds of the patients had already treated themselves with nasal packings. While one quarter used non-pneumatic nasal packings (NPNP) or pneumatic nasal packings (PNP), nearly half of the patients took only tissues to stop the bleeding. Patients with severe epistaxis used PNP more often than NPNP. Using nasal packings, most patients could stop their nosebleeds after a while. Patients using PNP reported the feeling of losing control less often and significant improvements

2019 Rhinology

9. Comparison of Early-period Results of Nasal Splint and Merocel Nasal Packs in Septoplasty (PubMed)

Comparison of Early-period Results of Nasal Splint and Merocel Nasal Packs in Septoplasty Several types of nasal packs are used postoperatively in septoplasty. In this study, we compared two commonly used nasal packing materials, the intranasal septal splint with airway and Merocel tampon, in terms of pain, bleeding, nasal obstruction, eating difficulties, discomfort in sleep, and pain and bleeding during removal of packing in the early period.The study group included 60 patients undergoing (...) septoplasty. Patients were divided into two groups (n=30 in each group). An intranasal splint with airway was used for the patients in the first group after septoplasty, while Merocel nasal packing was used for the second group. Patients were investigated in terms of seven different factors - pain, bleeding while the tampon was in place, nasal obstruction, eating difficulties, night sleep, pain during removal of the nasal packing, and bleeding after removal of packing.There was no statistically

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2017 Turkish Archives of Otorhinolaryngology

10. Is antibiotic prophylaxis in nasal packing for anterior epistaxis needed? (PubMed)

Is antibiotic prophylaxis in nasal packing for anterior epistaxis needed? Epistaxis is an extremely common problem that sometimes requires anterior nasal packing. Antibiotics are frequently indicated to prevent infectious complications, although the role of this measure is controversial. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified one systematic review including three primary studies, none of them randomized. We combined the evidence using (...) meta-analysis and generated a summary of findings table following the GRADE approach. We concluded it is not clear whether prophylactic antibiotics reduce infectious complications in patients with nasal packing for anterior epistaxis because the certainty of the evidence is very low.

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2016 Medwave

11. Prophylactic systemic antibiotics for anterior epistaxis treated with nasal packing in the emergency department. (PubMed)

Prophylactic systemic antibiotics for anterior epistaxis treated with nasal packing in the emergency department. Emergency Department (ED) patients presenting with spontaneous epistaxis who have anterior nasal packing are routinely prescribed systemic prophylactic antibiotics in spite of the lack of supporting evidence-based literature. Although there is literature that discusses infection rates with nasal packing for epistaxis and prophylactic antibiotics prescribing practices (...) of otolaryngologists, this is the first study to our knowledge that examines the practices of emergency physicians.The main objective of this study was to compare the infection rate between patients who were and were not prescribed prophylactic systemic antibiotics for anterior nasal packing in spontaneous epistaxis and to examine current management practices of antibiotic prescribing for these patients.A retrospective review of ED patients ≥ 18 years old with the discharge diagnosis of epistaxis was performed

2018 American Journal of Emergency Medicine

12. Comparison of the effect of the lidocaine, tetracaine, and articaine application into nasal packs on pain and hemorrhage after septoplasty. (PubMed)

Comparison of the effect of the lidocaine, tetracaine, and articaine application into nasal packs on pain and hemorrhage after septoplasty. We purposed to compare the effects of certain local anesthetics soaked Merocel nasal packs on hemorrhage and pain after septoplasty.This study is a prospective double-blind study that was done in patients undergoing septoplasty. The study was created with 90 patients. All patients were divided into four groups. The each group was applied 2% lidocaine plus (...)  < 0.05). There was no statistically significant difference between the lidocaine plus adrenaline, tetracaine and control groups in terms of postoperative hemorrhage (p > 0.05).Topical articaine plus adrenaline application in the nasal packs can be safely used for less pain and bleeding following septoplasty.

2018 European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

13. Post-turbinectomy nasal packing with Merocel versus glove finger Merocel: A prospective, randomized, controlled trial. (PubMed)

Post-turbinectomy nasal packing with Merocel versus glove finger Merocel: A prospective, randomized, controlled trial. Nasal packs are widely used after septoplasty and turbinectomy. We conducted a prospective, randomized, controlled clinical trial including 100 patients who underwent septoplasty with/or without turbinectomy randomized into two groups. In the first group (the Merocel group), a standard tampon was inserted at the end of surgery. In the second group (the glove finger group

2018 Ear, nose, & throat journal

14. Comparing nasal packing with trans-septal suturing following septoplasty: a randomized clinical trial. (PubMed)

Comparing nasal packing with trans-septal suturing following septoplasty: a randomized clinical trial. It has been shown that nasal packing after septoplasty is associated with several complications. Our aim was to compare post-septoplasty nasal packing and trans-septal suturing, in terms of complications and outcome of operation. This randomized clinical trial was performed on patients with deviated nasal septum who were candidates for septoplasty. Patients were visited three times after (...) operation (on the first 48 h, first week, and third post-operative month). Participants were checked for having common complications. Rhinomanometric evaluation was performed to measure nasal air flow and airway resistance, as indicators of operation efficacy, both prior to and after surgery. A total of 72 patients were allocated into the two trial arms. Patients in nasal pack group reported higher pain scores on the first 48 h (P < 0.001) and one week after surgery (P < 0.001). Epiphora (P = 0.028

2018 European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

15. Steroid vs. antibiotic impregnated absorbable nasal packing for wound healing after endoscopic sinus surgery: a randomized, double blind, placebo-controlled study. (PubMed)

Steroid vs. antibiotic impregnated absorbable nasal packing for wound healing after endoscopic sinus surgery: a randomized, double blind, placebo-controlled study. Endoscopic sinus surgery can lead to crusting or synechiae formation, which can affect the healing process.The aim of our study was to compare the influence of steroid versus antibiotic versus saline solution impregnated absorbable nasal spacers on postoperative wound healing and patient satisfaction.Eighty patients, 33 women and 47 (...) positive influence of steroid- and antibiotic-impregnated biodegradable nasal packing on the postoperative healing process and patient satisfaction compared to the saline soaked dressing.Copyright © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

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2018 Brazilian journal of otorhinolaryngology

16. Does glycerol have an effect on pain during nasal packing removal (PubMed)

Does glycerol have an effect on pain during nasal packing removal Background/aim: The aim of this study was to investigate the efficacy of lubricating and moistening of Merocel nasal packs with glycerol on reducing pain and bleeding during nasal packing removal in patients who had undergone endoscopic sinus surgery or with epistaxis. Materials and methods: Fifty patients were included in the study. Glycerol was used on one side while saline was used on the other side of the same patient (...) as a control. All patients were blinded to which side received glycerol and which side received saline. In the glycerol group, glycerol was infiltrated into the Merocel packing in the nasal cavity. In the saline group, 0.9% saline solution was infiltrated into the Merocel packing in the other nasal cavity of the same patient. Both applications were performed 15 min before removal of the packs. The patients were asked to score the severity of the pain that occurred in both nasal passages according

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2018 Turkish Journal of Medical Sciences

17. A study evaluating the effects of throat packs during nasal surgery: a randomised controlled trial. (PubMed)

A study evaluating the effects of throat packs during nasal surgery: a randomised controlled trial. The aims of this study were to identify differences in post-operative nausea and vomiting (PONV) and throat pain between throat packed and non-packed patient groups in nasal surgery. This was a prospective, double blind, randomised controlled trial. A water-soaked throat pack gauze was inserted in the mouth to occlude the oropharynx was used in the throat pack group. The second group received (...) (95% CI 1.13-2.52). At 2 and 6 h post-operatively, the mean throat pain VAS scores for the throat packed group were 2.1 and 2.3, respectively, and the mean throat pain VAS score for the non-throat packed group was 2.3 and 1.4, respectively. Statistical analysis showed non-significant difference between the two groups at 2 and 6 h post-operatively. The use of throat packs in nasal surgery does not confer PONV reduction benefit. The use of throat pack, however, is associated with a small

2018 European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

18. Can Pharyngeal Packing Prevent Postoperative Nausea and Vomiting in Nasal Surgery? (PubMed)

Can Pharyngeal Packing Prevent Postoperative Nausea and Vomiting in Nasal Surgery? We aimed to perform a meta-analysis for the efficacy of pharyngeal packing during nasal surgery in the prevention of postoperative nausea and vomiting (PONV).MEDLINE, SCOPUS, and the Cochrane database.Two authors independently searched the databases for relevant studies from inception to October 2017. Included studies were randomized controlled studies published in English comparing pharyngeal packing during (...) intubation (packing group) with no packing (control group) in patients who underwent nasal surgery. Outcomes of interest included the incidence of PONV and throat pain during the first 24 hours postsurgery.Ten studies were included in the meta-analysis. The incidence of moderate-to-severe PONV in the recovery room was significantly higher in the packing group than in the control group. However, the incidence of moderate-to-severe PONV significantly decreased and was lower in the packing group than

2018 Laryngoscope

19. Hot Off the Press: Topical Tranexamic Acid Compared with Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs. (PubMed)

Hot Off the Press: Topical Tranexamic Acid Compared with Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs. 29624770 2018 09 11 1553-2712 25 9 2018 Sep Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Hot Off the Press: Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs. 1062-1064 10.1111/acem.13422 Morgenstern Justin J

2018 Academic Emergency Medicine

20. Economic evaluation of floseal compared to nasal packing for the management of anterior epistaxis. (PubMed)

Economic evaluation of floseal compared to nasal packing for the management of anterior epistaxis. To evaluate the cost-effectiveness of Floseal, a topically applied hemostatic agent, and nasal packing for the management of epistaxis in Canada.Outcomes research, a cost-utility analysis.We developed a Markov model to compare the costs and health outcomes of Floseal with nasal packing over a lifetime horizon from the perspective of a publicly funded healthcare system. A cycle length of 1 year (...) strategy was associated with higher costs ($2,067) and greater QALYs (0.27) than nasal packing. Our findings were highly sensitive to discount rates, the cost of Floseal, and the cost of nasal packing. The probabilistic sensitivity analysis suggested that the probability that Floseal treatment is cost-effective reached 99% if the willingness-to-pay threshold was greater than $120,000 per QALY gained.Prior studies have demonstrated Floseal to be an effective treatment for anterior epistaxis

2018 Laryngoscope

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