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Nail Telangiectasia

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1. Nail Telangiectasia

Nail Telangiectasia Nail Telangiectasia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Nail Telangiectasia Nail Telangiectasia Aka (...) : Nail Telangiectasia , Scleroderma-Associated Nailfold Telangiectasia , Lupus Erythematosus-Associated Nailfold Telangiectasia From Related Chapters II. Associated Conditions Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Nail Telangiectasia." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Telangiectasia of nailfolds (C1274274) Concepts

2018 FP Notebook

2. Nail Telangiectasia

Nail Telangiectasia Nail Telangiectasia Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Nail Telangiectasia Nail Telangiectasia Aka (...) : Nail Telangiectasia , Scleroderma-Associated Nailfold Telangiectasia , Lupus Erythematosus-Associated Nailfold Telangiectasia From Related Chapters II. Associated Conditions Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Nail Telangiectasia." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Telangiectasia of nailfolds (C1274274) Concepts

2015 FP Notebook

3. Clubbing of the Nails (Follow-up)

, Ebrahim HM, Faheem KT. Nail changes in chronic renal failure patients under haemodialysis. J Eur Acad Dermatol Venereol . 2008 Nov. 22(11):1326-31. . Gefen AM, White AJ. Asymptomatic pulmonary arteriovenous malformations in children with hereditary hemorrhagic telangiectasia. Pediatr Pulmonol . 2017 Jun 13. . Rush PJ, Giorshev C, Shore A, Levinson H. The use of thermography in clubbing. Respir Med . 1992 May. 86(3):257-9. . Ward RW, Chin R Jr, Keyes JW Jr, Haponik EF. Digital clubbing. Demonstration (...) Clubbing of the Nails (Follow-up) Clubbing of the Nails Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNTk0Ni10cmVhdG1lbnQ= processing

2014 eMedicine.com

4. Clubbing of the Nails (Diagnosis)

manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi J Kidney Dis Transpl . 2013 Jan. 24(1):36-40. . Salem A, Al Mokadem S, Attwa E, Abd El Raoof S, Ebrahim HM, Faheem KT. Nail changes in chronic renal failure patients under haemodialysis. J Eur Acad Dermatol Venereol . 2008 Nov. 22(11):1326-31. . Gefen AM, White AJ. Asymptomatic pulmonary arteriovenous malformations in children with hereditary hemorrhagic telangiectasia. Pediatr Pulmonol . 2017 Jun 13. . Rush PJ (...) Clubbing of the Nails (Diagnosis) Clubbing of the Nails: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNTk0Ni1vdmVydmlldw== processing > Clubbing of the Nails Updated

2014 eMedicine.com

5. Clubbing of the Nails (Treatment)

, Ebrahim HM, Faheem KT. Nail changes in chronic renal failure patients under haemodialysis. J Eur Acad Dermatol Venereol . 2008 Nov. 22(11):1326-31. . Gefen AM, White AJ. Asymptomatic pulmonary arteriovenous malformations in children with hereditary hemorrhagic telangiectasia. Pediatr Pulmonol . 2017 Jun 13. . Rush PJ, Giorshev C, Shore A, Levinson H. The use of thermography in clubbing. Respir Med . 1992 May. 86(3):257-9. . Ward RW, Chin R Jr, Keyes JW Jr, Haponik EF. Digital clubbing. Demonstration (...) Clubbing of the Nails (Treatment) Clubbing of the Nails Treatment & Management: Medical Care, Surgical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNTk0Ni10cmVhdG1lbnQ= processing

2014 eMedicine.com

6. Clubbing of the Nails (Overview)

manifestations and nail changes in patients with end-stage renal disease on hemodialysis. Saudi J Kidney Dis Transpl . 2013 Jan. 24(1):36-40. . Salem A, Al Mokadem S, Attwa E, Abd El Raoof S, Ebrahim HM, Faheem KT. Nail changes in chronic renal failure patients under haemodialysis. J Eur Acad Dermatol Venereol . 2008 Nov. 22(11):1326-31. . Gefen AM, White AJ. Asymptomatic pulmonary arteriovenous malformations in children with hereditary hemorrhagic telangiectasia. Pediatr Pulmonol . 2017 Jun 13. . Rush PJ (...) Clubbing of the Nails (Overview) Clubbing of the Nails: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNTk0Ni1vdmVydmlldw== processing > Clubbing of the Nails Updated

2014 eMedicine.com

7. Systemic sclerosis (scleroderma)

blood vessels, fibrosis of skin and internal organs, and production of auto-antibodies. History and exam presence of risk factors Raynaud's phenomenon digital pits or ulcers swelling of the hands and feet skin thickening loss of function of hands sclerodactyly heartburn, reflux, and dysphagia bloating faecal incontinence arthralgias and myalgias abnormal nail-fold capillaroscopy telangiectasia subcutaneous calcinosis dyspnoea dry crackles at lung bases tendon friction rub abrupt onset moderate

2018 BMJ Best Practice

8. Cirrhosis

to be irreversible in its advanced stages. [Figure caption and citation for the preceding image starts]: Laparoscopic view of a cirrhotic liver Courtesy of Dr Eugene Schiff and Dr Lennox Jeffers; used with permission [Citation ends]. History and exam presence of risk factors abdominal distension jaundice and pruritus coffee-ground vomitus and black stool (melaena) hand and nail features (e.g., leukonychia, palmar erythema, spider angiomata) facial features (e.g., telangiectasia, spider angiomata, jaundiced

2018 BMJ Best Practice

9. Bruising

as bruising on exposed areas (such as the arms or legs) after minor trauma. May be associated with menorrhagia. Hereditary haemorrhagic telangiectasia (HHT) A rare autosomal dominant genetic disorder which leads to mucocutaneous telangiectasia of the skin, mucous membranes, and organs. There may be a positive family history, recurrent nosebleeds, fatigue, nail changes, and hair loss. Ehlers-Danlos syndrome This causes joint hypermobility and skin translucency and hyperextensibility. It may present (...) vasculitis, such as . Brittle hair and nails — suggests nutritional factors, ageing, hypothyroidism, or rarely hereditary haemorrhagic telangiectasia. Examine the joints for: Abnormalities suggestive of an inflammatory arthropathy (such as rheumatoid arthritis). See the Prodigy topic on for more information. Hyperextensibility or elasticity — suggestive of . Swelling and tenderness — may indicate haemarthrosis, suggesting . Tenderness — may be seen in acute leukaemia or neuroblastoma. Examine the abdomen

2017 Prodigy

10. CRACKCast E120 – Dermatologic presentations

Measles Dengue Acute meningococcemia Meningococcal disease may manifest as one of three syndromes: meningitis, bacteremia, or bacteremic pneumonia. Drug induced Chemotherapy drug: Acral erythema (e.g. due to doxorubicin) Hand-foot skin reaction Erythema multiforme [4] Describe the various presentations of tinea and their treatment Tinea refers to superficial dermatophytic infection of the skin, hair, and/or nails, usually by the Trichophyton organism. Tinea Corporis Tinea refers to superficial (...) dermatophytic infection of the skin, hair, and/or nails, usually by the Trichophyton organism. Infections of the body, groin, and extremities usually respond to topical antifungal agents. A number of effective topical antifungal agents are available, including clotrimazole, haloprogin, miconazole, tolnaftate, terbinafine, naftifine, and others. Two or three daily applications of the cream form of any of these preparations result in healing of most superficial lesions in 1 to 3 weeks. Tinea Capitis Tinea

2017 CandiEM

11. Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting

posterior hairline 40 Broad short-appearing neck 40 Pterygium colli (webbed neck) 25 Thorax Broad chest (shield chest) 30 Inverted nipples 5 Skin, nails, and hair Increased skin ridge count 30 Lymphedema of hands and feet 25 Multiple pigmented naevi 25 Nail hypoplasia/dystrophy 10 Vitiligo 5 Alopecia 5 Skeleton Bone age delay 85 Decreased bone mineral content 50–80 Cubitus valgus 50 Short fourth metacarpal 35 Genu valgum 35 Congenital hip luxation 20 Scoliosis 10 Madelung deformity 5 Heart Bicuspid (...) with unexplained growth failure or pubertal delay, with or without the constellation of the lymphedema sequence (edema of the hands or feet, nuchal fold, neck webbing, low hairline and hyperconvex or hypoplastic nails); characteristic facial features such as epicanthal folds, downslanting palpebral fissures, low-set ears and micrognathia; left-sided cardiac anomalies, especially coarctation of the aorta, bicuspid aortic valve and aortic stenosis; markedly elevated follicle-stimulating hormone (FSH); cubitus

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2016 European Society of Human Reproduction and Embryology

12. European Society of Endocrinology Clinical practice guidelines for the care of girls and women with Turner syndrome

posterior hairline 40 Broad short-appearing neck 40 Pterygium colli (webbed neck) 25 Thorax Broad chest (shield chest) 30 Inverted nipples 5 Skin, nails, and hair Increased skin ridge count 30 Lymphedema of hands and feet 25 Multiple pigmented naevi 25 Nail hypoplasia/dystrophy 10 Vitiligo 5 Alopecia 5 Skeleton Bone age delay 85 Decreased bone mineral content 50–80 Cubitus valgus 50 Short fourth metacarpal 35 Genu valgum 35 Congenital hip luxation 20 Scoliosis 10 Madelung deformity 5 Heart Bicuspid (...) with unexplained growth failure or pubertal delay, with or without the constellation of the lymphedema sequence (edema of the hands or feet, nuchal fold, neck webbing, low hairline and hyperconvex or hypoplastic nails); characteristic facial features such as epicanthal folds, downslanting palpebral fissures, low-set ears and micrognathia; left-sided cardiac anomalies, especially coarctation of the aorta, bicuspid aortic valve and aortic stenosis; markedly elevated follicle-stimulating hormone (FSH); cubitus

2017 European Society of Endocrinology

13. Skin Reactions

Skin Reactions Skin Reactions | ONS Hello [ Name ] ! Renew Membership: Hello [ Name ] ! Renew Membership: Menu Search Skin Reactions A number of different types of that affect the skin, hair, and nails can occur with cancer treatment. ONS PEP resources focus on those effects other than alopecia that are most often encountered, including rash, palmar-plantar erythrodysesthesia (PPE) (hand-foot syndrome), xerosis, paronychia, photosensitivity, and pruritus. Cancer treatment-related skin reactions (...) on the agent used), xerosis (3%–55%), pruritus (8%–52%), and paronychia (12%–16% of patients receiving epidermal growth factor receptor [EGFR] inhibitors). Those effects can be episodic, wax and wane, or spontaneously resolve. Sensitivity to sunlight, telangiectasias, and hyperpigmentation can be long-term or even permanent side effects of treatment. Immune-Related Adverse Events With Immunotherapy Skin toxicity is one of the most common immune-related adverse events (irAEs) with immunotherapy treatment

2017 Oncology Nursing Society Putting Evidence into Practice (PEP)

16. Radiation therapy for early Dupuytren's disease

patients treated with 32 Gy of radiation within a median follow-up of 40 months. 5.11 Skin atrophy was reported in 3% (7/206) of patients in the case series of 206 patients treated with 32 Gy of radiation, in more than 4 weeks of follow-up. In the same study, telangiectasia was reported in 3% (6/206) of patients, in more Radiation therapy for early Dupuytren's disease (IPG573) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights (...) ). Page 6 of 9than 4 weeks of follow-up. Mild skin atrophy with occasional telangiectasia was reported in 7% (14/208) of hands in the case series of 135 patients within a median follow-up of 13 years. 5.12 Alteration of heat and pain sensation was reported in 4% (8/198) of hands in the RCT of 129 patients treated with 30 Gy or 21 Gy (minimum follow-up of 1 year). Sensory affection was reported in 2% (4/206) of patients in the case series of 206 patients treated with 32 Gy of radiation, in more than 4

2017 National Institute for Health and Clinical Excellence - Interventional Procedures

17. Genetics of Skin Cancer (PDQ®): Health Professional Version

30–40 y) XD > AD Xq24-27 [ ] Unknown Hypotrichosis (variable),[ ] hypohidrosis, milia, follicular atrophoderma (dorsal hands), and multiple BCCs (aged teens to early 20s) [ ] AD 16q12-q13 [ , ] CYLD [ , ] Cylindroma (forehead, scalp, trunk, and pubic area),[ , ] trichoepithelioma (around nose), spiradenoma, and BCC AD [ ] Unknown Unknown Multiple BCC (infundibulocystic type) AR > AD Unknown Unknown Ectodermal dysplasia (hypotrichosis, hypodontia, and nail dystrophy [anonychia and trachyonychia

2018 PDQ - NCI's Comprehensive Cancer Database

19. Management of vulval conditions

early and start treatment as they can lead to scarring and complete stenosis. The lesions consist of friable 7 telangiectasia with patchy erythema which are responsible for the common symptoms of postcoital bleeding, dyspareunia and a variable discharge which is often serosanguinous. As erosions heal synaechiae and scarring can develop. 18 This type is also seen in the oral mucosa although synaechia are uncommon. The term vulvo-vaginal gingival syndrome is used when erosive disease occurs (...) of the skin and nails to look for other signs of psoriasis Management Further Investigation ? Skin punch biopsy if the diagnosis is in doubt Treatment 28 Recommended Regimens ? Avoidance of irritating factors ? Use of emollient soap substitute ? Topical corticosteroid - weak to moderate steroids are preferred but if insufficient to induce a response then intensive short term potent steroid such as clobetasol propionate 0.05% may be used. A combined preparation containing antifungal and/or antibiotic may

2014 British Association for Sexual Health and HIV

20. Transcriptomic analysis of FUCA1 knockdown in keratinocytes reveals new insights in the pathogenesis of fucosidosis skin lesions. (PubMed)

Transcriptomic analysis of FUCA1 knockdown in keratinocytes reveals new insights in the pathogenesis of fucosidosis skin lesions. Fucosidosis is a rare lysosomal storage disease which has been classified into two subtypes, depending on the severity of clinical signs and symptoms. Fucosidosis patients' skin abnormalities include angiokeratoma corporis diffusum, widespread telangiectasia, thick skin, hyperhidrosis and hypohidrosis, acrocyanosis and distal transverse nail bands. It has been

2018 Experimental Dermatology

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