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NIH Stroke Scale

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101. Repeated Muscle Vibration in Acute Stroke

are recorded. All patients undergo a clinical examination, performed at all time-points by an experienced investigator, blinded to group assignment and different from the recruiting one. Clinical evaluation consists of stroke severity evaluation, by means of NIH Stroke Scale; motor and functional limbs abilities are evaluated by using both the Fugl-Meyer scale and the Motricity Index; post-stroke spasticity is assessed with Ashworth scale, modified by Bohannon and Smith. All participants undergo a daily (...) corresponds to normal traction (66 points for the upper limb, 34 for the lower one) and a minimum score of 0 (no traction) Stroke Recovery [ Time Frame: 4 ± 1 days ] Stroke recovery is expressed as the differences over time (from T-0 to T-1) between the two groups concerning NIH Stroke Scale scores. This scale assesses the stroke severity; it consists of 11 items and the total score goes from a minimum of 0 = normal neurological examination at a maximum of 42, severe severe neurological deficit

2018 Clinical Trials

102. TEC4Home Stroke

Systolic Hypertension Transient Ischemic Attack Cerebrovascular Accident Detailed Description: The investigators propose a two-year pilot study (TEC4Home Stroke) to assess the feasibility of using home telemonitoring technology in managing hypertension among patients with minor stroke/TIA (NIH Stroke Scale Score <5) at the VGH Stroke Prevention Clinic (SPC). The Vancouver Stroke Program SPC receives 1200 referrals per year for assessment of patients with strokes or TIAs. Of the total number of patients (...) TEC4Home Stroke TEC4Home Stroke - Feasibility of Home Telemonitoring Technology in Managing Hypertension Among Stroke/TIA Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. TEC4Home Stroke

2018 Clinical Trials

103. Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression. (PubMed)

treated with conventional drug fluoxertine hydrochloride for 2 months, and patients in the experimental group were treated with gastrodin. The levels of 5-HT and neurotrophic factors in blood were measured using the enzyme-linked immunosorbent assay (ELISA) kit before, and at 1 and 2 months after treatment. The Hamilton Depression Scale (HAMD), Activities of Daily Living (ADL) scale, NIH Stroke Scale/Score (NIHSS) and Stroke Impact Scale (SIS) were used to evaluate the efficacy of treatment. Treatment (...) Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression. Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression (PSD) were investigated. A total of 78 PSD patients were selected in Binzhou City Center Hospital from September 2013 to December 2016. Patients were randomly divided into the control group and experimental group, 39 patients in each group. Patients in the control group were

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2018 Experimental and therapeutic medicine

104. Recovernow: A Multicentre Of Tablet-Based Speech Therapy For Post-Stroke Aphasia

Institutes of Health Stroke Scale [ Time Frame: 3 years ] The NIH Stroke Scale is a widely used tool that was built to assess the cognitive effects of a stroke. In more scientific terms, it "provides a quantitative measure of stroke-related neurologic deficit".In a treatment setting, the scale has three major purposes: It evaluates the severity of the stroke It helps determine the appropriate treatment It predicts patient outcomes.The scale is made up of 11 different elements that evaluate specific (...) , and 76-above is mild Secondary Outcome Measures : Cost-effectiveness [ Time Frame: 3 years ] The results of the cost-effectiveness analysis will be expressed as the incremental cost per one-unit improvement in AQ and the incremental cost per one quality-adjusted life year (QALY) gained Other Outcome Measures: Stroke and Aphasia Quality of Life Scale [ Time Frame: 3 years ] The Stroke and Aphasia Quality of Life Scale (SAQOL-39) is an interview-administered self-report scale that is based

2018 Clinical Trials

105. Early Findings on Functional Connectivity Correlates of Behavioral Outcomes of Brain-Computer Interface Stroke Rehabilitation Using Machine Learning (PubMed)

found to be important correlates of across several behavioral outcomes and were stable upon inclusion of clinical variables as well. NIH Stroke Scale and motor impairment severity were the most influential clinical variables. Comparatively, linear SVR models aided in evaluation of contribution of individual correlates and seed regions while non-linear SVR models achieved higher performance in prediction of behavioral outcomes. (...) Test, Nine-Hole Peg Test, and Barthel Index as well as subjective measures including the Stroke Impact Scale. The present analysis focused on neuroplasticity and behavioral outcomes measured across pre-intervention, post-intervention and 1-month post-intervention to study immediate and carry-over effects. Rs-FC, changes in rs-FC within the motor network and the behavioral measures at preceding stages were used as input features and behavioral measures and associated changes at succeeding stages

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2018 Frontiers in neuroscience

106. Prevalence and factors associated with memory disturbance and dementia after acute ischemic stroke (PubMed)

. The demographics and clinical characteristics, previous illness and past medical history, and laboratory test results of the patients were collected from the medical records, while depression screening, NIH stroke scale (NIHSS) scoring and mini mental state examination (MMSE) were performed using particular medical record forms. The prevalence of memory disturbance and dementia was 56.6, 41.6 and 38.2% before discharge, three and six months after stroke, respectively. Based on logistic regression analysis, age (...) Prevalence and factors associated with memory disturbance and dementia after acute ischemic stroke Prevalence and risk factors associated with memory disturbance and dementia were determined in acute ischemic stroke (AIS) patients in hospitals before discharge, three and six months after stroke. A prospective cohort study was conducted during January-December 2017 with 401 AIS patients admitted to Srinagarind Hospital, Khon Kaen Hospital and Chum Phae Hospital, Khon Kaen, Thailand

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2018 Neurology international

107. Zero Degree Head Positioning in Hyperacute Large Artery Ischemic Stroke

clinical assessors blinded to the intervention to determine neurologic deterioration on the NIH Stroke Scale Score following positioning to either zero degree or thirty degree heights. Primary Purpose: Treatment Official Title: Zero Degree Head Positioning in Hyperacute Large Artery Ischemic Stroke Actual Study Start Date : September 25, 2018 Estimated Primary Completion Date : June 30, 2022 Estimated Study Completion Date : June 30, 2023 Arms and Interventions Go to Arm Intervention/treatment (...) of bed (HOB) position will be selected through computerized randomization, and will include either zero degree positioning or thirty degree HOB elevation Outcome Measures Go to Primary Outcome Measures : Early Neurologic Deterioration (END) on the National Institute of Health Stroke Scale Occurring During the Positioning Intervention [ Time Frame: Measured every 10 minutes from initiation of positioning up until thrombectomy commences or 2 hours - whichever comes first ] Two or more point-worsening

2018 Clinical Trials

108. Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania

more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 80 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Participant is 18 years of age or older Participant has experienced a CT-confirmed ischemic stroke w/in 14 days of enrollment Exclusion Criteria: NIH Stroke Scale (...) post-enrollment for an in-person study visit. At each time point, investigators will draw 10-15 mL of blood; download medication adherence data from participants' electronic pill bottles; and inquire about adverse events and evaluate patient disability through the modified Rankin Scale. If participants stop taking their daily pill, stroke specific reasons for non-adherence will be inquired including dysphagia, self-administration, and other concerns. Primary assessments will be for safety

2018 Clinical Trials

109. Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania. (PubMed)

.Adults with new-onset stroke (<14 days), confirmed by head CT, admitted to MNH.Modified Rankin scale (mRS) and vital status.Of 149 subjects (mean age 57; 48% female; median NIH stroke scale (NIHSS) 19; 46% ischemic stroke; 54% hemorrhagic), implementation of treatments included: dysphagia screening (80%), deep venous thrombosis prophylaxis (0%), aspirin (83%), antihypertensives (89%) and statins (95%). There was limited ability to detect atrial fibrillation and carotid artery disease and no acute (...) Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania. Given the high post-stroke mortality and disability and paucity of data on the quality of stroke care in Sub-Saharan Africa, we sought to characterize the implementation of stroke-focused treatments and 90-day outcomes of neuroimaging-confirmed stroke patients at the largest referral hospital in Tanzania.Prospective cohort study.Muhimbili National Hospital (MNH) in Dar es Salaam, July 2016-March 2017

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2018 International Journal for Quality in Health Care

110. Quality of care for ischemic stroke in China vs India: Findings from national registries. (PubMed)

prior stroke, hypertension, atrial fibrillation, and smoking). Hospitalized Indian patients had greater stroke severity (median NIH Stroke Scale score 10 vs 4), higher rates of IV thrombolysis within 3 hours (7.5% vs 2.4%), greater in-hospital mortality (7.9% vs 1.2%), and worse outcome (3-month modified Rankin Scale score 0-2, 49.3% vs 78.1%) (all p < 0.001). The poorer clinical outcomes were attributable mainly to greater stroke severity in IUCSP patients. Chinese patients more often received (...) Quality of care for ischemic stroke in China vs India: Findings from national registries. To understand stroke risk factors, status of stroke care, and opportunities for improvement as China and India develop national strategies to address their disproportionate and growing burden of stroke.We compared stroke risk factors, acute management, adherence to quality performance measures, and clinical outcomes among hospitalized ischemic stroke patients using data from the Indo-US Collaborative

2018 Neurology

111. Dual antiplatelet therapy pretreatment in IV thrombolysis for acute ischemic stroke. (PubMed)

hemorrhage, favorable functional outcome (modified Rankin Scale score 0-1), and 3-month mortality.Among 790 IVT patients, 58 (7%) were on DAPP before stroke (mean age 68 ± 13 years; 57% men; median NIH Stroke Scale score 8). DAPP+ patients were older with more risk factors compared to DAPP- patients. The rates of sICH were similar between groups (3.4% vs 3.2%). In multivariable analyses adjusting for potential confounders, DAPP was associated with higher odds of asymptomatic intracranial hemorrhage (odds (...) Dual antiplatelet therapy pretreatment in IV thrombolysis for acute ischemic stroke. We sought to determine the safety and efficacy of IV thrombolysis (IVT) in acute ischemic stroke (AIS) patients with a history of dual antiplatelet therapy pretreatment (DAPP) in a prospective multicenter study.We compared the following outcomes between DAPP+ and DAPP- IVT-treated patients before and after propensity score matching (PSM): symptomatic intracranial hemorrhage (sICH), asymptomatic intracranial

2018 Neurology

112. Commentary: Early Screening Parameters for Dysphagia in Acute Ischemic Stroke (PubMed)

Neuroscience, Sapienza University of Rome, Rome, Italy. eng Journal Article Comment 2018 03 20 Switzerland Front Neurol 101546899 1664-2295 Cerebrovasc Dis. 2017;44(5-6):285-290 28903096 Dysphagia NIH Stroke Scale Stroke 2018 02 05 2018 02 28 2018 4 5 6 0 2018 4 5 6 0 2018 4 5 6 1 epublish 29615955 10.3389/fneur.2018.00148 PMC5869246 Stroke. 1999 Apr;30(4):744-8 10187872 Eur Neurol. 2015;74(3-4):171-7 26492033 Cerebrovasc Dis. 2017;44(5-6):285-290 28903096 (...) Commentary: Early Screening Parameters for Dysphagia in Acute Ischemic Stroke 29615955 2018 11 14 1664-2295 9 2018 Frontiers in neurology Front Neurol Commentary: Early Screening Parameters for Dysphagia in Acute Ischemic Stroke. 148 10.3389/fneur.2018.00148 Toscano Massimiliano M Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy. Viganò Alessandro A Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy. Di Piero Vittorio V Department of Human

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2018 Frontiers in neurology

113. Exercise and Motor Learning After Stroke

information, Layout table for eligibility information Ages Eligible for Study: 18 Years to 85 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Age 18-85 Single, unilateral, chronic stroke (>6 months post-stroke), confirmed by MRI or CT scan Score >1 on question 1b and >0 on question 1c of the NIH Stroke Scale Able to walk at self-selected speed without assistance from another person Resting heart rate between 40-100 beats per minute (...) Exercise and Motor Learning After Stroke Exercise and Motor Learning After Stroke - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Exercise and Motor Learning After Stroke The safety and scientific validity

2018 Clinical Trials

114. Enhancement of Stroke Rehabilitation With Levodopa

to complete the item using a 3-point ordinal scale (0=cannot perform; 1=performs partially and 2= performs fully). FMMA total scores range from 0 (no movements) to 100 (normal movements) with 66 points for movements of the upper limbs (FMMA-UE) and 34 for those of the lower limbs (FMMA-LE) Secondary Outcome Measures : Change in NIH-Stroke Scale score (NIHSS) [ Time Frame: Assessed at Day 0 (Randomization), 5 weeks after randomization, 3 months +/- 14 days after randomization, 6 months +/- 20 days after (...) for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Acute ischemic stroke ≤ 7 days prior to randomization Clinically meaningful hemiparesis (i.e. ≥ 3 points on arm plus leg motor items of the NIH-stroke scale score) 24-hour latency period in case of thrombolysis or thrombectomy In-hospital rehabilitation required Capable to participate in standardized rehabilitation therapy

2018 Clinical Trials

115. Safety and Effectiveness Evaluation of the ISS System in Treatment of Acute Ischemic Stroke

Safety and Effectiveness Evaluation of the ISS System in Treatment of Acute Ischemic Stroke Safety and Effectiveness Evaluation of the ISS System in Treatment of Acute Ischemic Stroke - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Safety and Effectiveness Evaluation of the ISS System in Treatment of Acute Ischemic Stroke (ImpACT-1) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03733236 Recruitment Status : Completed First Posted : November 7, 2018 Last Update Posted : November 7, 2018 Sponsor

2018 Clinical Trials

116. Non-invasive TRanscutaneous Cervical Vagus Nerve Stimulation as a Treatment for Acute Stroke; Safety and Feasibility Study

in NIH Stroke Scale Score) within 24 hours death within 24 hours Other Outcome Measures: Proportion of treatment eligible patients (feasibility measure 1) [ Time Frame: 6 hours ] Proportion of eligible patients in whom nVNS can be started within the first 6 hours. Proportion of patients completing all pre-specified treatment doses (feasibility measure 2) [ Time Frame: 12 hours ] Proportion of enrolled patients who receive all the pre-specified treatment doses per protocol. Stroke onset to treatment (...) ] Local irritation or skin reaction during treatment application Acute coronary syndrome (secondary safety measure 2) [ Time Frame: 24 hours ] Acute coronary syndrome Symptomatic intracerebral hemorrhage (secondary safety measure 3) [ Time Frame: 24 hours ] Symptomatic intracerebral hemorrhage: ≥ 4 points increase in NIH Stroke Scale Score (NIHSS) together with a PH2 (parenchymal hematoma-2) type intracerebral hemorrhage Death, clinical worsening, and acute coronary syndrome (secondary safety measure

2018 Clinical Trials

117. Who should undergo a comprehensive cognitive assessment after a stroke? A cognitive risk score. (PubMed)

Disorders and Stroke-Canadian Stroke Network battery 6 months after stroke, we used multivariable logistic regression and bootstrap analyses to determine factors associated with NCDs. Independent, internally validated factors were included in a cognitive risk score.Cognitive impairment was present in 170 of the 320 patients with a Rankin Scale score ≥1. The backward logistic regression selected 4 factors (≥73% of the permutations): NIH Stroke Scale score on admission ≥7 (odds ratio [OR] 2.73, 95 (...) % confidence interval [CI] 1.29-4.3, p = 0.005), multiple strokes (OR 3.78, 95% CI 1.6-8, p = 0.002), adjusted Mini-Mental State Examination (MMSEadj) score ≤27 (OR 6.69, 95% CI 3.9-11.6, p = 0.0001), and Fazekas score ≥2 (OR 2.34, 95% CI 1.3-4.2, p = 0.004). The cognitive risk score computed with these 4 factors provided good calibration, discrimination (overoptimism-corrected C = 0.793), and goodness of fit (Hosmer-Lemeshow test p = 0.99). A combination of Rankin Scale score ≥1, cognitive risk score ≥1

2018 Neurology

118. Stroke in Egyptian Clinical REgisTry

not otherwise specified patients will be weighted with a score reported for NIH Stroke Scale will be grouped into Mild stroke (>0-6 on NIHSS) moderate (>6 - 10 on NIHSS) severe (>10 - 20 on NIHSS) and Grave (>20 on NIHSS) Modified Rankin Scale at Discharge [ Time Frame: 90 days post discharge from hospital ] Patients grouped by Modified Rankin Scale at discharge Risk-Adjusted Mortality Ratio for Ischemic-Only and Ischemic and Hemorrhagic models [ Time Frame: 30 days post discharge from hospital ] A ratio (...) -Thrombolysis Endovascular treatment Rehabilitation , mobilization , bulbar care, secondary prevention Stroke unit calibration Prehospital care organization Patients with stroke without structured management Control subject who have stroke and did not managed according to the SECRET 6 level metrics Outcome Measures Go to Primary Outcome Measures : The National Institutes of Health Stroke Scale (NIHSS) reported [ Time Frame: 30 days post discharge from hospital ] Severity of ischemic stroke and stroke

2018 Clinical Trials

119. Effect of stroke thrombolysis predicted by distal vessel occlusion detection. (PubMed)

) no occlusion on CTA, and (3) infarction confirmed on follow-up. Favorable morphologic response was defined as smaller values of final infarction volume divided by initial CBF deficit volume (FIV/CBF). Favorable functional outcome was defined as modified Rankin Scale score of ≤2 after 90 days and decrease in NIH Stroke Scale score of ≥3 from admission to 24 hours (∆NIHSS).Among patients with negative CTA (n = 107), 58 (54%) showed a distal occlusion on waveletCTA. There was no difference between patients (...) Effect of stroke thrombolysis predicted by distal vessel occlusion detection. Among ischemic stroke patients with negative CT angiography (CTA), we aimed to determine the predictive value of enhanced distal vessel occlusion detection using CT perfusion postprocessing (waveletCTA) for the treatment effect of IV thrombolysis (IVT).Patients were selected from 1,851 consecutive patients who had undergone CT perfusion. Inclusion criteria were (1) significant cerebral blood flow (CBF) deficit, (2

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2018 Neurology

120. Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients. (PubMed)

the fitness of each model was determined using the ROC curve to predict the power of each logistic regression model.The non telestroke admitted more patients (62% vs 38%), when compared with the telestroke. Although the telestroke admitted fewer patients, it excluded 11% and administered thrombolysis therapy to 89% of stroke patients with hypertension. In the non telestroke group, adjusted odd ratios showed significant associations of NIH stroke scale score (OR = 1.059, 95% CI, 1.025-1.093, P < 0.001 (...) Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients. In acute ischemic stroke patients, telestroke technology provides sustainable approaches to improve the use of thrombolysis therapy. How this is achieved as it relates to inclusion or exclusion of clinical risk factors for thrombolysis is not fully understood. We investigated this in a population of hypertensive stroke patients.Structured data from a regional stroke registry

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2018 BMC Neurology

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