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NIH Stroke Scale

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101. Cerebrolysin REGistry Study in Stroke

Stroke Ischemia Cerebral Infarction Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases Pathologic Processes Brain Infarction Brain Ischemia Cerebrolysin Neuroprotective Agents Protective Agents Physiological Effects of Drugs Nootropic Agents (...) with Cerebrolysin Observation criteria: Signed Informed Consent Clinical diagnosis of acute ischemic stroke confirmed by imaging Moderate to severe neurological deficits with NIH Stroke Scale (NIHSS) 8 to 15, both inclusive No prior stroke No prior disability Patient's independence prior to stroke onset (pre-morbid mRS of 0 or 1) Reasonable expectation of successful follow-up (max. 100 days) The study follows the recommendations of the Principles for Good Research on Comparative Effectiveness (GRACE). In order

2018 Clinical Trials

102. Cortical Priming to Optimize Gait Rehabilitation Post Stroke

at Chicago: Gait Brain stimulation tDCS Walking Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases (...) Collaborator: National Institutes of Health (NIH) Information provided by (Responsible Party): University of Illinois at Chicago Study Details Study Description Go to Brief Summary: Over four million stroke survivors currently living in the United States are unable to walk independently in the community. To increase the effectiveness of gait rehabilitation, it is critical to develop therapies that are based on an understanding of brain adaptations that occur after stroke. This project will be the first

2018 Clinical Trials

103. Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial

and/or their families are willing to participate in this study and agree to sign informed consent. Exclusion Criteria: Patients with premorbid modified Rankin Scale(mRS) score ≥2 CT showed multiple infarctions(low density> 1/3 cerebral hemisphere). Transient ischemic attack. Epileptic seizure when stroke onset. Intracranial tumor, arteriovenous malformation and aneurysm. Iatrogenic Stroke. Thrombectomy is planned. Cardioembolism and atrial fibrillation. Myocardial infarction history within 3 months. Severe cerebral (...) Last Update Posted: January 11, 2019 Last Verified: June 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Stroke Ischemia Cerebral Infarction Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases Pathologic Processes Brain Infarction Brain Ischemia Aspirin Anti

2018 Clinical Trials

104. Therapies for Recovery of Hand Function After Stroke

University Kessler Foundation National Institutes of Health (NIH) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Information provided by (Responsible Party): Jayme Knutson, MetroHealth Medical Center Study Details Study Description Go to Brief Summary: After a stroke, it is very common to lose the ability to open the affected hand. The purpose of this study is to compare the effects of three different therapies on recovery of hand function after stroke (...) hand under the guidance of a trained therapist. Outcome Measures Go to Primary Outcome Measures : Box and Blocks Test (BBT) change [ Time Frame: 0 to 12 weeks, 0 to 36 weeks ] The BBT counts how many blocks a patient can pick up, move over a barrier, and release in 60 seconds. Secondary Outcome Measures : Stroke Upper Limb Capacity Scale (SULCS) change [ Time Frame: 0 to 12 weeks, 0 to 36 weeks ] The SULCS is a 10-item test in which participants are given a score of 0 or 1 on their performance

2018 Clinical Trials

105. Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke

by medical records Has more than a moderate stroke (NIH Stroke Scale > 20) Can read and write English. To ensure participants can understand instructions in clinic and home exercise sessions Exclusion Criteria: More than moderate motor deficits (Fugl-Meyer UE Assessment < 32/66) More than mild cognitive impairment (Mini-Mental Status Examination < 24) More than mild balance deficits (Berg Balance Scale <45) Minimal or no impairments from their stroke (NIH Stroke Scale < 6) Currently receiving (...) : No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Rachel Proffitt, University of Missouri-Columbia: Upper Extremity Hemiparesis Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases

2018 Clinical Trials

106. Internet-based CBT After Stroke Pilot

attempts are excluded History of schizophrenia or schizoaffective disorder Active participation in face-to-face psychotherapy prior to stroke Patients with a history of dementia are excluded Patients with aphasia, defined as a score of 1 or greater on NIH Stroke Scale Item 9 are excluded. Patients without regular internet access through a computer, tablet or smartphone are excluded. Subjects requiring long-term inpatient nursing care are excluded. For patients enrolled as inpatients, individuals being (...) information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases

2018 Clinical Trials

107. Recovernow: A Multicentre Of Tablet-Based Speech Therapy For Post-Stroke Aphasia

Institutes of Health Stroke Scale [ Time Frame: 3 years ] The NIH Stroke Scale is a widely used tool that was built to assess the cognitive effects of a stroke. In more scientific terms, it "provides a quantitative measure of stroke-related neurologic deficit".In a treatment setting, the scale has three major purposes: It evaluates the severity of the stroke It helps determine the appropriate treatment It predicts patient outcomes.The scale is made up of 11 different elements that evaluate specific (...) a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Stroke Aphasia Communication Disorders Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases Speech Disorders Language Disorders Neurobehavioral Manifestations Neurologic Manifestations Signs and Symptoms Neurodevelopmental Disorders Mental Disorders

2018 Clinical Trials

108. SURE 18 Registry -Asahi Chikai Black 18 in LVO Stroke

and unable to attend to own bodily needs without assistance Severe disability; bedridden, incontinent and requiring constant nursing care and attention Dead Change in NIH Stroke Scale (NIHSS) [ Time Frame: 24 hours ] The score for each ability is a number between 0 (normal functioning) to 4 (completely impaired). The NIHSS has 11 different items and the highest possible score is 42. The higher the score, the more impaired a stroke patient is. Number of neurovascular guidewires required per case [ Time (...) ) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Sampling Method: Non-Probability Sample Study Population For the prospective portion, patients will be enrolled if their doctor decides to treat them with the ASAHI Chikai Black 18 Neurovascular Guidewire. For the retrospective portion, 50 consecutive mechanical thrombectomy cases will be evaluated. Criteria Inclusion Criteria: Male or female patients presenting with acute anterior cerebral circulation large vessel occlusive stroke ASPECT

2018 Clinical Trials

109. Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

(such as hemianopia) preventing full view of the screen Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest). Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study Inability to understand or follow commands in English due to aphasia or other reason Diffuse or multifocal infarcts Substantial arm pain preventing participation for 90 minutes a day New spasticity treatment (...) , 2018 Last Update Posted: August 20, 2018 Last Verified: August 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Marc Slutzky, Northwestern University: rehabilitation Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases

2018 Clinical Trials

110. Early Administration of Edoxaban After Acute Ischemic Stroke in Patients With Non-valvular Atrial Fibrillation

after stroke event. After 1 day: transient ischemic attacks After 3 days: mild ischemic strokes (NIHSS <8) After 6 days: moderate ischemic strokes (NIHSS 8−16) After 12 days: severe ischemic strokes (NIHSS >16) - NIHSS: National Institute of Health Stroke Scales Other Name: Lixiana Active Comparator: Conventional edoxaban initiation group No antithrombotic treatment† -- then standard dose of edoxaban (30 or 60 mg) according to '3-6' rule. Drug: Edoxaban 1-3-6-12 rule* Anticoagulation in patients (...) with acute ischemic stroke and atrial fibrillation can be initiated from the following days after stroke event. After 1 day: transient ischemic attacks After 3 days: mild ischemic strokes (NIHSS <8) After 6 days: moderate ischemic strokes (NIHSS 8−16) After 12 days: severe ischemic strokes (NIHSS >16) - NIHSS: National Institute of Health Stroke Scales Other Name: Lixiana Outcome Measures Go to Primary Outcome Measures : recurrent ischemic strokes [ Time Frame: at Day 10−14 ] The incidence rate

2018 Clinical Trials

111. Effect of stroke thrombolysis predicted by distal vessel occlusion detection. Full Text available with Trip Pro

) no occlusion on CTA, and (3) infarction confirmed on follow-up. Favorable morphologic response was defined as smaller values of final infarction volume divided by initial CBF deficit volume (FIV/CBF). Favorable functional outcome was defined as modified Rankin Scale score of ≤2 after 90 days and decrease in NIH Stroke Scale score of ≥3 from admission to 24 hours (∆NIHSS).Among patients with negative CTA (n = 107), 58 (54%) showed a distal occlusion on waveletCTA. There was no difference between patients (...) Effect of stroke thrombolysis predicted by distal vessel occlusion detection. Among ischemic stroke patients with negative CT angiography (CTA), we aimed to determine the predictive value of enhanced distal vessel occlusion detection using CT perfusion postprocessing (waveletCTA) for the treatment effect of IV thrombolysis (IVT).Patients were selected from 1,851 consecutive patients who had undergone CT perfusion. Inclusion criteria were (1) significant cerebral blood flow (CBF) deficit, (2

2018 Neurology

112. Insulin resistance and clinical outcomes after acute ischemic stroke. (Abstract)

assessment of insulin resistance (HOMA-IR) score was calculated using fasting blood glucose and insulin levels measured 8.3 ± 7.8 days after onset. Study outcomes were neurologic improvement (≥4-point decrease in NIH Stroke Scale score or 0 at discharge), poor functional outcome (modified Rankin Scale score of ≥3 at 3 months), and 3-month prognosis (stroke recurrence and all-cause mortality). Logistic regression analysis was used to evaluate the association of the HOMA-IR score with clinical outcomes.The (...) Insulin resistance and clinical outcomes after acute ischemic stroke. In this study, we aimed to determine whether insulin resistance is associated with clinical outcomes after acute ischemic stroke.We enrolled 4,655 patients with acute ischemic stroke (aged 70.3 ± 12.5 years, 63.5% men) who had been independent before admission; were hospitalized in 7 stroke centers in Fukuoka, Japan, from April 2009 to March 2015; and received no insulin therapy during hospitalization. The homeostasis model

2018 Neurology

113. Efficacy and safety of Cerebrolysin treatment in early recovery after acute ischemic stroke: a randomized, placebo-controlled, double-blinded, multicenter clinical trial. (Abstract)

after the onset of stroke. The patients were treated with Cerebrolysin (30 mL over seven days followed by 10 mL until day 30) or placebo once daily over a period of four weeks. Efficacy was primarily assessed by the NIH Stroke Scale at day 30, and additional parameters included the modified Rankin Scale, the Clinical Global Impression, the Patient Global Satisfaction (PGS) and the Mini Mental State Examination (MMSE). Nonparametric statistical procedures employing the Wilcoxon-Mann-Whitney test were (...) used for data analysis. Safety and tolerability were assessed by adverse events, vital signs, and laboratory parameters. Results.The estimated effect size on the change from baseline in the NIH Stroke Scale on day 30 indicated a medium to large superiority of cerebrolysin compared to placebo (Mann-Whitney [MW] 0.66; 95% confidence interval [CI] 0.55-0.78, P=0.005). Similar effect sizes were reported for the modified Ranking Scale (MW 0.65; 95% CI 0.54-0.76; P=0.010) and the Clinical Global

2018 Journal of medicine and life Controlled trial quality: predicted high

114. A randomized controlled study of intravenous fluid in acute ischemic stroke. (Abstract)

A randomized controlled study of intravenous fluid in acute ischemic stroke. To compare the outcome of patients with acute ischemic stroke who received or did not receive intravenous fluid.This study was a prospective, multicenter, randomized, open-label trial with blinded outcome assessment. We enrolled acute ischemic stroke patients without dehydration aged between 18 and 85 years with NIH Stroke Scale score (NIHSS) score from 1 to 18 who presented within 72h after onset. Patients were (...) -IV fluid group and 3.3% of the IV fluid group (p=0.02). Predictors of neurological deterioration were higher NIHSS score, higher plasma glucose, and increased pulse rate. There was no difference in the primary efficacy outcome, NIHSS≤4 at day 7, 83.3% vs 86.7%, p=0.61 or secondary efficacy outcomes.Administration of 0.9% NaCl 100ml/h for 72h in patients with acute ischemic stroke is safe and may be associated with a reduced risk of neurological deterioration. These study findings support the use

2018 Clinical neurology and neurosurgery Controlled trial quality: uncertain

115. Moderate-Intensity Exercise Versus High-Intensity Interval Training to Recover Walking Post-Stroke

testing from the past year available to rule out) Evidence of significant arrhythmia or myocardial ischemia on treadmill ECG graded exercise test in the absence of recent (past year) more definitive clinical testing (e.g. stress nuclear imaging) with negative result Hospitalization for cardiac or pulmonary disease within past 3 months Implanted pacemaker or defibrillator Significant ataxia or neglect (score of 2 on NIH stroke scale item 7 or 11) Severe lower limb spasticity (Ashworth >2) Recent (...) by the data archive selected. Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Pierce Boyne, University of Cincinnati: Rehabilitation Locomotion Aerobic Intensity Dosing Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases

2018 Clinical Trials

116. Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients. Full Text available with Trip Pro

the fitness of each model was determined using the ROC curve to predict the power of each logistic regression model.The non telestroke admitted more patients (62% vs 38%), when compared with the telestroke. Although the telestroke admitted fewer patients, it excluded 11% and administered thrombolysis therapy to 89% of stroke patients with hypertension. In the non telestroke group, adjusted odd ratios showed significant associations of NIH stroke scale score (OR = 1.059, 95% CI, 1.025-1.093, P < 0.001 (...) Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients. In acute ischemic stroke patients, telestroke technology provides sustainable approaches to improve the use of thrombolysis therapy. How this is achieved as it relates to inclusion or exclusion of clinical risk factors for thrombolysis is not fully understood. We investigated this in a population of hypertensive stroke patients.Structured data from a regional stroke registry

2018 BMC Neurology

117. Intravenous Autologous Mesenchymal Stem Cells Transplantation to Treat Middle Cerebral Artery Infarct

or other space-occupying lesion on brain MRI Evidence of hemorrhagic stroke on brain CT or MRI Experiences transient ischemic attack or lacunar infarct Has any acute or chronic infections such as Hepatitis B, Hepatitis C and HIV Is diagnosed with concurrent malignancy or primary hematological disorders Renal impairment indicated with serum creatinine greater than 200 umol/l or creatinine clearance less than 30 ml/min Liver impairment indicated with serum aspartate transaminase and serum alanine (...) intravenous infusion of autologous bone marrow-derived mesenchymal stem cells concurrently with standard medical care. Outcome Measures Go to Primary Outcome Measures : Change in NIH Stroke Scale [ Time Frame: 1 year ] Change in Barthel Index [ Time Frame: 1 year ] Change in modified Rankin Scale [ Time Frame: 1 year ] Change in size of infarct based on brain MRI stroke sequences [ Time Frame: 1 year ] Secondary Outcome Measures : Change in Stroke Specific Quality of Life Scale [ Time Frame: 1 year

2011 Clinical Trials

118. Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States Full Text available with Trip Pro

likely to receive preventive health services. Spanish-speaking Hispanics were far less likely to be knowledgeable of heart attack and stroke symptoms than English-speaking Hispanics, NHBs, and NHWs. Language and Health Literacy There is an important role for health literacy, because it influences the ability to negotiate health systems, understand and act on health treatment and advice, and seek timely and appropriate health care. , Lower health literacy predicted increased all-cause mortality among (...) Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019 January 2019 January 2019 January 2019 January 2019 January 2019 This site uses cookies. By continuing to browse

2014 American Heart Association

119. Guidelines for the Prevention of Stroke in Women

regularly, as they were for prenatal care. Postpartum preeclampsia is associated with a high risk for stroke and may be the underlying cause of severe postpartum headaches. 152 Transient elevations in BP are common post partum because of volume redistribution, iatro- genic administration of fluid, alterations in vascular tone, and use of nonsteroidal anti-inflammatory drugs, 153–155 but persis- tently elevated BP should be categorized and treated accord- ing to the adult guidelines. 140 A 2010 Cochrane (...) risk for preeclampsia, 158 but there are insufficient data to support a recommendation. Treatment of Elevated BP During Pregnancy, Including Preeclampsia The central autoregulatory plateau in pregnancy is estimated at 120 mm Hg, and women with moderate to severe high BP in pregnancy, especially those with preeclampsia, are at risk for loss of central cerebral vascular autoregulation. The association between high BP and stroke risk in women with preeclampsia is not linear, such that stroke can occur

2014 Congress of Neurological Surgeons

120. Society of Interventional Radiology Position Statement on Endovascular Acute Ischemic Stroke Interventions

and Recanalization of Stroke Clots Using Embolectomy, mRS = modi?ed Rankin scale, NIH = National Institutes of Health, NIHSS = National Institutes of Health Stroke Scale, TICI = Thrombolysis In Cerebral Infarction, tPA= tissue plasminogen activator, TREVO= Thrombectomy Revascularization of large Vessel Occlusions in Acute Ischemic Stroke In February 2013, the world of stroke interventions changed. Three trials were presented at the 2013 International Stroke Conference and then published in the New England (...) not have a large vessel occlusion as the cause of their ischemic stroke have much better outcomes compared with those with a large vessel occlusion. Patients without large vessel occlusions include those with peripheral branch occlusions or lacunar infarcts, who tend to do well with IV tPA alone (10). By de?nition, thrombectomy cannot be performed unless there is a large vessel thrombus. Current clinical practice reserves endo- vascular thrombectomy for patients who have a large vessel occlu- sion

2013 Society of Interventional Radiology

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