How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,570 results for

NIH Stroke Scale

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

61. Recommendations for the Implementation of Telehealth in Cardiovascular and Stroke Care: A Policy Statement From the American Heart Association Full Text available with Trip Pro

for their engagement at all steps of the healthcare process, mobile technologies can strengthen the provider-patient relationship. Mobile Stroke Units Mobile stroke units are emergency medical services vehicles equipped with a computed tomography scanner, tissue-type plasminogen activator, and a means to access stroke expertise either on board or via telehealth that can be used to diagnose and treat acute ischemic stroke in the field. Early attempts at mobile ambulance-based telehealth were hampered by inadequate (...) Recommendations for the Implementation of Telehealth in Cardiovascular and Stroke Care: A Policy Statement From the American Heart Association Recommendations for the Implementation of Telehealth in Cardiovascular and Stroke Care: A Policy Statement From the American Heart Association | Circulation Search Hello Guest! Login to your account Email Password Keep me logged in Search March 2019 March 2019 March 2019 March 2019 March 2019 February 2019 February 2019 February 2019 February 2019

2016 American Heart Association

62. Poststroke Depression: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

been noted in several animal models. , Last, depression has been reported after transient ischemic attack and minor stroke (National Institutes of Health Stroke Scale score ≤5 at discharge). , Proposed biological factors contributing to PSD include lesion location, genetic susceptibility, inflammation, neurogenesis in response to ischemia, alterations in neurotrophic factors, disruption of cortico-striato-pallido-thalamic-cortical projections, and alterations in serotonergic, noradrenergic (...) -analysis of 51 studies conducted before June 2004 and revealed a pooled frequency estimate of PSD of 33% (95% confidence interval [CI], 29%–36%). All studies included ischemic stroke, most included intracerebral hemorrhage, and the majority excluded subarachnoid hemorrhage and transient ischemic attack. Valid methods were used to ascertain depression in these studies. The primary end point was the proportion of patients who met the diagnostic category of depression, which included the following: (1

2016 American Heart Association

63. Guidelines for adult stroke rehabilitation and recovery

in the 43 prevention studies reviewed was the Morse Fall Scale. 184 The Berg Balance Scale has demonstrated good sensitivity and specificity in predicting falls in individuals with stroke. 185 Several federal and professional associations have developed fall prevention toolkits that include risk assessment instru- ments and protocols (eg, the National Center of Patient Safety Falls Toolkit, the Centers for Disease Control and Prevention Stopping Elderly Accidents, Deaths and Injuries Toolkit, the AHRQ (...) care for the foreseeable future. Despite the extensive resources devoted to stroke rehabili- tation and aftercare, large-scale, rigorous, clinical trials in this field have been few and have been conducted only in the past decade or so. Thus, many gaps continue to be seen in the evi- dence base for stroke rehabilitation, for which smaller trials of less rigorous design provide the only available data, and in some cases, even these are not yet available. Certain aspects of stroke rehabilitation care

2016 American Academy of Neurology

64. Prevention of stroke in patients with silent cerebrovascular disease Full Text available with Trip Pro

and treatment decisions. Existing AHA/ASA guidelines for early management of symptomatic ischemic stroke recommend cardiac rhythm monitoring in all patients, as well as noninvasive vascular imaging of the cervical vessels and intracranial vessels (when knowledge of intracranial steno-occlusive disease would alter management) in all patients with ischemic stroke or transient ischemic attack (TIA), and by logical extension may also pertain to patients with clinically unrecognized infarction. The most common (...) , to discuss clinical considerations, and to offer suggestions for future research on stroke prevention in patients with 3 cardinal manifestations of silent cerebrovascular disease: silent brain infarcts, magnetic resonance imaging white matter hyperintensities of presumed vascular origin, and cerebral microbleeds. The writing committee found strong evidence that silent cerebrovascular disease is a common problem of aging and that silent brain infarcts and white matter hyperintensities are associated

2016 American Academy of Neurology

65. Telemedicine quality and outcomes in stroke

benchmarked telestroke consultations as they related to time performance and reviewed the clinical data from 8 stroke centers that provided 235 telestroke consults over a 7-month period. Of the 203 consults that met their study criteria, 60 of 203 or ≈ 30% carried a diagnosis of stroke or transient ischemic attack, and 13 of 60 stroke cases (21.7%) were recommended for intravenous tPA. Although the mean response time (time from arrival to physician log-on) was 76 minutes, the percent of patients eligible (...) , that are used as guides in the endorsement process. Prior Experience With the Use of Quality Measures in Stroke Since 2001, more than a dozen performance measure guidelines have been published and sponsored or cosponsored by the American Heart Association/American Stroke Association. These include guidelines for the treatment of chronic heart failure, myocardial infarction, coronary artery disease and hypertension, and acute ischemic stroke. In acute stroke, implementation of quality improvement initiatives

2016 American Academy of Neurology

66. Basic Concepts and Potential Applications of Genetics and Genomics for Cardiovascular and Stroke Clinicians Full Text available with Trip Pro

. These variants do not change gene activity enough to cause disease by themselves but instead need to be combined with other variants in other genes or with environmental factors for disease to occur. This is the case with most cardiovascular disorders for which there are many contributing factors, for example, hypercholesterolemia, myocardial infarction, and ischemic stroke. All of these differences at the DNA level are called polymorphisms, of which there are several types ( ). Single-nucleotide (...) Basic Concepts and Potential Applications of Genetics and Genomics for Cardiovascular and Stroke Clinicians Basic Concepts and Potential Applications of Genetics and Genomics for Cardiovascular and Stroke Clinicians | Circulation: Cardiovascular Genetics Search Hello Guest! Login to your account Email Password Keep me logged in Search February 2019 January 2019 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump

2015 American Heart Association

67. 2015 AHA/ASA Focused Update of the 2013 Guidelines for the Early Management of Patients with Acute Ischemic Stroke Regarding Endovascular Treatment

with a major ischemic stroke defined by NIHSS score =10 who received intravenous r-tPA within 3 hours and were likely to or known to have occlusion of a major cerebral artery. Those who showed clear hypodensity in greater than one third of the middle cerebral artery (MCA) territory on non- enhanced CT were excluded. No other imaging was required. An amendment midway through the trial allowed screening with CT angiography (CTA) for patients with NIHSS score >8. More than 95% received a clinical diagnosis (...) in Emergency Neurological Deficits–Intra-Arterial; IA, intra-arterial; IAT, intra-arterial therapy; ICA, internal carotid artery; IMS III, Interventional Management of Stroke Trial III; IV, intravenous; MCA, middle cerebral artery; MERCI, Mechanical Embolus Removal in Cerebral Ischemia; MR, magnetic resonance; MR CLEAN, Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke; MR RESCUE, MR and Recanalization of Stroke Clots Using Embolectomy; MRA, magnetic resonance

2015 Congress of Neurological Surgeons

68. 2015 aha/asa focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment Full Text available with Trip Pro

Scale; r-tPA, recombinant tissue-type plasminogen activator; REVASCAT, Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours; SWIFT PRIME, Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment of Acute Ischemic Stroke; and TICI, Thrombolysis in Cerebral Infarction. Table 4. Selected Clinical Outcomes for Recent Randomized, Clinical Trials of Endovascular Treatments for Acute Ischemic Stroke Outcomes (...) ischemic stroke within 8 hours who were ineligible for intravenous r-tPA or had persistent vessel occlusion after intravenous r-tPA. Patients were divided into 2 subgroups by pretreatment CT or magnetic resonance imaging (MRI) into those with a favorable or those with an unfavorable penumbral pattern with the use of imaging criteria based on a previous study. Patients were randomly allocated 1:1 to standard medical care or endovascular therapy (MERCI [Mechanical Embolus Removal in Cerebral Ischemia

2015 American Academy of Neurology

69. Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke

; INR, international normalized ratio; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; OAC, oral anticoagulant; rtPA, recombinant tissue-type plasminogen activator; and SBP, systolic blood pressure. Modified from de Los Rios la Rosa et al. Copyright © 2012, American Heart Association, Inc. However, given the hemorrhage risk associated with alteplase, there are numerous other clinical, radiological, and laboratory-related exclusion criteria for alteplase (...) … Placebo … 1711 (29.3) … … … … ATLANTIS indicates Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke; ECASS II, European Cooperative Acute Stroke Study II; IST-3, Third International Stroke Trial; MCA, middle cerebral artery; NINDS, National Institute of Neurological Diseases and Stroke; and tPA, tissue-type plasminogen activator. * Only the first 276 patients received placebo; open control thereafter. Overall, 1711 stroke patients ≥80 years of age participated

2015 American Academy of Neurology

70. Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke Full Text available with Trip Pro

Cooperative Acute Stroke Study III; ED, emergency department; INR, international normalized ratio; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; OAC, oral anticoagulant; rtPA, recombinant tissue-type plasminogen activator; and SBP, systolic blood pressure. Modified from de Los Rios la Rosa et al. Copyright © 2012, American Heart Association, Inc. However, given the hemorrhage risk associated with alteplase, there are numerous other clinical, radiological, and laboratory (...) d) Recent acute myocardial infarction (within previous 3 mo) Notes The checklist includes some FDA-approved indications and contraindications for administration of intravenous rtPA for acute ischemic stroke. Recent guideline revisions have modified the original FDA-approved indications. A physician with expertise in acute stroke care may modify this list. Onset time is defined as either the witnessed onset of symptoms or the time last known normal if symptom onset was not witnessed. In patients

2015 American Heart Association

71. Hesperidin reduces adverse symptomatic intracerebral hemorrhage by promoting TGF-β1 for treating ischemic stroke using tissue plasminogen activator. (Abstract)

therapies. Patients with ischemic stroke were assigned into two groups in a random fashion, to receive either rt-PA + placebo (Pc) or rt-PA + hesperidin. Treatment outcome was evaluated 24 h after the initial reperfusion using the transcranial Doppler ultrasonography (TCD) and the NIH Stroke Scale (NIHSS). Further, serum concentrations of transforming growth factor (TGF)-β1, matrix metalloproteinase (MMP)-2, and MMP-9 were examined. Following the initial administration, stroke patients continued (...) Hesperidin reduces adverse symptomatic intracerebral hemorrhage by promoting TGF-β1 for treating ischemic stroke using tissue plasminogen activator. Treatment with recombinant tissue plasminogen activator (rt-PA) is the most effective therapeutic option against brain ischemic stroke at the present time. However, elevated incidence of symptomatic intracerebral hemorrhage (SIH) greatly hinders ideal treatment outcome of rt-PA. We sought to assess the impacts of hesperidin on SIH following rt-PA

2019 Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Controlled trial quality: uncertain

72. Lower serum retinoic acid level for prediction of higher risk of mortality in ischemic stroke. (Abstract)

. The significance of serum RA level, NIH Stroke Scale score, and established risk factors in predicting mortality were determined. The integrated discrimination improvement (IDI) and net reclassification improvement (NRI) statistics were applied in statistical analysis.Of the 1,530 patients enrolled, 325 died within 6 months of admission, with an all-cause mortality of 21.2% and CVD-related mortality of 13.1%. In multivariable analysis, RA levels were expressed as quartiles with the clinical variables (...) Lower serum retinoic acid level for prediction of higher risk of mortality in ischemic stroke. To explore the association between serum retinoic acid (RA) level in patients with acute ischemic stroke (AIS) and mortality risk in the 6 months after admission.From January 2015 through December 2016, patients admitted to 3 stroke centers in China for first-ever AIS were screened. The primary endpoint was all-cause mortality or cardiovascular disease (CVD) mortality in the 6 months after admission

2019 Neurology

73. Outcome of endovascular therapy in stroke with large vessel occlusion and mild symptoms. (Abstract)

Outcome of endovascular therapy in stroke with large vessel occlusion and mild symptoms. To compare outcomes after endovascular therapy (EVT) and IV thrombolysis (IVT) in patients with stroke with emergent large vessel occlusion (LVO) and mild neurologic deficits.This was a retrospective analysis of patients from the Swiss Stroke Registry with admission NIH Stroke Scale score ≤5 and LVO treated by EVT (± IVT) vs IVT alone. The primary endpoint was favorable functional outcome (modified Rankin (...) ). Patients with EVT showed a nonsignificant trend toward higher mRS score at 3 months (p = 0.717), while the proportion of surviving patients with high disability was comparably very low in both groups (p = 0.419). Mortality was slightly higher among those with EVT (9.3% vs 2.8%; p = 0.06), and symptomatic intracranial hemorrhage was a rare event in both groups (2.8% vs 0%; p = 0.997).In acute ischemic stroke, EVT and IVT appear similarly effective in achieving favorable outcome at 3 months for patients

2019 Neurology

74. MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS. (Abstract)

MRI-based thrombolytic therapy in patients with acute ischemic stroke presenting with a low NIHSS. Treatment of patients with stroke presenting with minor deficits remains controversial, and the recent Potential of rtPA for Ischemic Strokes with Mild Symptoms (PRISMS) trial, which randomized patients to thrombolysis vs aspirin, did not show benefit. We studied the safety and efficacy of thrombolysis in a population of patients with acute stroke presenting with low NIH Stroke Scale (NIHSS (...) ) scores screened using MRI.The NIH Natural History of Stroke database was reviewed from January 2006 to December 2016 to identify all patients with an initial NIHSS score ≤5 who received thrombolysis within 4.5 hours of symptom onset after being screened with MRI. The 24-hour postthrombolysis MRIs were reviewed for hemorrhagic transformation. Primary outcomes were symptomatic intracranial hemorrhage (sICH) and favorable 90-day outcome modified Rankin Scale score 0-1. Subgroup analysis was performed

2019 Neurology

75. Topographic correlation of infarct area on CT perfusion with functional outcome in acute ischemic stroke. (Abstract)

circulation ischemic stroke who underwent CT angiography (CTA) and CTP at admission between February 2011 and October 2014. On CTP, the volume of ischemic core and penumbra was measured using the Alberta Stroke Program Early CT Score (ASPECTS). CTA findings were also noted, including the site of occlusion and regional leptomeningeal collateral (rLMC) score. Functional outcome was defined by modified Rankin Scale (mRS) score obtained at discharge. Associations of CTP and CTA parameters with mRS scores (...) at discharge were assessed using multivariable proportional odds logistic regression models.RESULTSThe median age was 67 years (range 19-95 years), and the median NIH Stroke Scale score was 16 (range 2-35). In a multivariable analysis adjusting for potential confounding variables, having an infarct on CTP scans in the following regions was associated with a worse mRS score at discharge: insula ribbon (p = 0.043), perisylvian fissure (p < 0.001), motor strip (p = 0.007), M2 (p < 0.001), and M5 (p = 0.023

2019 Journal of Neurosurgery

76. Young male with syphilitic cerebral arteritis presents with signs of acute progressive stroke: A case report. Full Text available with Trip Pro

) causes the severe obstruction of blood flow without complete occlusion, leading to an increased risk of infarction. In this patient, formation of the MT resulted in the infarction of the smaller vessels and narrowing of the larger vessels. The partial dislodgment of the MT from the arterial wall of the larger vessels occluded the smaller vessels, leading to infarction.Standard pharmacotherapy for the treatment of the cerebral infarction and a single course of penicillin were applied.Muscle strength (...) was recovered. The Glasgow Coma Scale score was 15, whereas the NIH Stroke Scale score was 0. The increase in blood flow of the right MCA was accompanied by severe stenosis with compensation of the anterior communicating artery. In addition, moderate to severe stenosis of the right vertebral artery and the basilar artery was suspected. There was a possibility that the right posterior communicating artery was recruited for compensation.Progressive stroke was the initial symptom of the neurosyphilis. Disease

2019 Medicine

77. Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression. Full Text available with Trip Pro

treated with conventional drug fluoxertine hydrochloride for 2 months, and patients in the experimental group were treated with gastrodin. The levels of 5-HT and neurotrophic factors in blood were measured using the enzyme-linked immunosorbent assay (ELISA) kit before, and at 1 and 2 months after treatment. The Hamilton Depression Scale (HAMD), Activities of Daily Living (ADL) scale, NIH Stroke Scale/Score (NIHSS) and Stroke Impact Scale (SIS) were used to evaluate the efficacy of treatment. Treatment (...) Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression. Effects of gastrodin on 5-HT and neurotrophic factor in the treatment of patients with post-stroke depression (PSD) were investigated. A total of 78 PSD patients were selected in Binzhou City Center Hospital from September 2013 to December 2016. Patients were randomly divided into the control group and experimental group, 39 patients in each group. Patients in the control group were

2018 Experimental and therapeutic medicine Controlled trial quality: uncertain

78. Periprocedural heparin use in acute ischemic stroke endovascular therapy: the TREVO 2 trial. Full Text available with Trip Pro

who did not receive periprocedural heparin (HEP-) while undergoing MERCI or TREVO clot retrieval.Of 173 patients, 58 (34%) received periprocedural heparin including 40 who received one preprocedural bolus (median 3000 units). Baseline characteristics among HEP+ and HEP- patients were similar except HEP+ patients had a lower NIH Stroke Scale (NIHSS) score (17 vs 19; p=0.04), lower IV tissue plasminogen activator use (38% vs 64%; p<0.01), and a higher median ASPECTS score (8.0 vs 7.0; p=0.02). HEP (...) + patients were more likely to have vertebrobasilar and middle cerebral artery (MCA)-M1 occlusions but less likely to have internal carotid artery and MCA-M2 occlusions (p=0.04). Time from symptom onset to puncture was similar in the two groups while procedure duration was longer in HEP+ patients (99 vs 83 min; p<0.01). Thrombolysis In Cerebral Infarction (TICI) 2b-3 reperfusion rates, embolization to unaffected territories, access site complications, and intracranial hemorrhages were similar between

2018 Journal of neurointerventional surgery Controlled trial quality: predicted high

79. Opportunities for intervention: stroke treatments, disability and mortality in urban Tanzania. (Abstract)

.Adults with new-onset stroke (<14 days), confirmed by head CT, admitted to MNH.Modified Rankin scale (mRS) and vital status.Of 149 subjects (mean age 57; 48% female; median NIH stroke scale (NIHSS) 19; 46% ischemic stroke; 54% hemorrhagic), implementation of treatments included: dysphagia screening (80%), deep venous thrombosis prophylaxis (0%), aspirin (83%), antihypertensives (89%) and statins (95%). There was limited ability to detect atrial fibrillation and carotid artery disease and no acute (...) thrombolysis or thrombectomy. Of ischemic subjects, 19% died and 56% had severe disability (mRS 4-5) at discharge; 49% died by 90 days. Of hemorrhagic subjects, 33% died and 49% had severe disability at discharge; 50% died by 90 days. In a multivariable model, higher NIHSS score but not dysphagia, unconsciousness, or patient age was predictive of death by 90 days.The 90-day mortality of stroke presenting at MNH is 50%, much higher than in higher income settings. Although severe stroke presentations

2018 International Journal for Quality in Health Care

80. Quality of care for ischemic stroke in China vs India: Findings from national registries. Full Text available with Trip Pro

prior stroke, hypertension, atrial fibrillation, and smoking). Hospitalized Indian patients had greater stroke severity (median NIH Stroke Scale score 10 vs 4), higher rates of IV thrombolysis within 3 hours (7.5% vs 2.4%), greater in-hospital mortality (7.9% vs 1.2%), and worse outcome (3-month modified Rankin Scale score 0-2, 49.3% vs 78.1%) (all p < 0.001). The poorer clinical outcomes were attributable mainly to greater stroke severity in IUCSP patients. Chinese patients more often received (...) Quality of care for ischemic stroke in China vs India: Findings from national registries. To understand stroke risk factors, status of stroke care, and opportunities for improvement as China and India develop national strategies to address their disproportionate and growing burden of stroke.We compared stroke risk factors, acute management, adherence to quality performance measures, and clinical outcomes among hospitalized ischemic stroke patients using data from the Indo-US Collaborative

2018 Neurology

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>