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Myocardial Infarction Stabilization

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121. Myocardial Infarction in Childhood (Follow-up)

Myocardial Infarction in Childhood (Follow-up) Myocardial Infarction in Childhood Treatment & Management: Approach Considerations, Initial Supportive Measures, Surgical Revascularization Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvODk3NDUzLXRyZWF0bWVudA== processing > Myocardial Infarction in Childhood Treatment & Management Updated: May 23, 2014 Author: Louis I Bezold, MD; Chief Editor: Stuart Berger, MD Share Email Print Feedback Close Sections Sections Myocardial Infarction in Childhood Treatment Approach Considerations Medical care for a disease or condition that predisposes children to acute myocardial infarction (AMI) is discussed more fully elsewhere (see and ). The primary treatment in patients with anomalous left coronary artery (LCA

2014 eMedicine Pediatrics

122. Complications of Myocardial Infarction (Diagnosis)

Complications of Myocardial Infarction (Diagnosis) Complications of Myocardial Infarction: Overview, Arrhythmic Complications of MI, Arrhythmic Complications: Supraventricular Tachyarrhythmias Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTY0OTI0LW92ZXJ2aWV3 processing > Complications of Myocardial Infarction Updated: Dec 18, 2014 Author: Ashok K Kondur, MD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Complications of Myocardial Infarction Overview Overview Myocardial infarction (MI) due to coronary artery disease is a leading cause of death in the United States, where more than 1 million people have acute myocardial infarctions (AMIs) each year. [ ] The advent of coronary care units and early reperfusion

2014 eMedicine.com

123. Myocardial Infarction (Diagnosis)

Myocardial Infarction (Diagnosis) Myocardial Infarction: Practice Essentials, Background, Definitions Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTU1OTE5LW92ZXJ2aWV3 processing > Myocardial Infarction Updated (...) : Jul 19, 2018 Author: A Maziar Zafari, MD, PhD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Myocardial Infarction Overview Practice Essentials Myocardial infarction (MI) (ie, heart attack) is the irreversible death (necrosis) of heart muscle secondary to prolonged lack of oxygen supply (ischemia). Approximately 1.5 million cases of MI occur annually in the United States. See the images below. Acute myocardial infarction, reperfusion type. In this case

2014 eMedicine Emergency Medicine

124. Myocardial Infarction (Follow-up)

adjunctive use of GP II b /III a inhibitors is not recommended but may be considered in selected cases. [ , ] Previous Next: Non-ST-Elevation (NSTE) ACS Key points in the management of patients with non–ST-elevation acute coronary syndrome (NSTE-ACS) (unstable angina and non-STE myocardial infarction [NSTEMI]) is early evaluation and assessment of hemodynamic and electrical stability, estimatation of the overall risk in these patients, and guidance of therapy. There are two alternative management (...) or bivalirudin), as fondaparinux is associated with a higher risk of catheter thrombosis; this was demonstrated in the Fifth Organization to Assess Strategies in Ischemic Syndromes (OASIS-5) trial. [ , , ] Previous Next: Additional Aspects of Management and Late Hospital Care After the initial management and stabilization of the patient in the early and critical phase of acute myocardial infarction (MI), the goals of care for these patients is to restore normal activities, prevent long-term complications

2014 eMedicine Emergency Medicine

125. Myocardial Infarction (Overview)

Myocardial Infarction (Overview) Myocardial Infarction: Practice Essentials, Background, Definitions Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTU1OTE5LW92ZXJ2aWV3 processing > Myocardial Infarction Updated (...) : Jul 19, 2018 Author: A Maziar Zafari, MD, PhD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Myocardial Infarction Overview Practice Essentials Myocardial infarction (MI) (ie, heart attack) is the irreversible death (necrosis) of heart muscle secondary to prolonged lack of oxygen supply (ischemia). Approximately 1.5 million cases of MI occur annually in the United States. See the images below. Acute myocardial infarction, reperfusion type. In this case

2014 eMedicine.com

126. Myocardial Infarction (Treatment)

adjunctive use of GP II b /III a inhibitors is not recommended but may be considered in selected cases. [ , ] Previous Next: Non-ST-Elevation (NSTE) ACS Key points in the management of patients with non–ST-elevation acute coronary syndrome (NSTE-ACS) (unstable angina and non-STE myocardial infarction [NSTEMI]) is early evaluation and assessment of hemodynamic and electrical stability, estimatation of the overall risk in these patients, and guidance of therapy. There are two alternative management (...) or bivalirudin), as fondaparinux is associated with a higher risk of catheter thrombosis; this was demonstrated in the Fifth Organization to Assess Strategies in Ischemic Syndromes (OASIS-5) trial. [ , , ] Previous Next: Additional Aspects of Management and Late Hospital Care After the initial management and stabilization of the patient in the early and critical phase of acute myocardial infarction (MI), the goals of care for these patients is to restore normal activities, prevent long-term complications

2014 eMedicine.com

127. Complications of Myocardial Infarction (Treatment)

Complications of Myocardial Infarction (Treatment) Complications of Myocardial Infarction: Overview, Arrhythmic Complications of MI, Arrhythmic Complications: Supraventricular Tachyarrhythmias Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTY0OTI0LW92ZXJ2aWV3 processing > Complications of Myocardial Infarction Updated: Dec 18, 2014 Author: Ashok K Kondur, MD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Complications of Myocardial Infarction Overview Overview Myocardial infarction (MI) due to coronary artery disease is a leading cause of death in the United States, where more than 1 million people have acute myocardial infarctions (AMIs) each year. [ ] The advent of coronary care units and early reperfusion

2014 eMedicine.com

128. Ventricular Septal Rupture Following Myocardial Infarction (Treatment)

Ventricular Septal Rupture Following Myocardial Infarction (Treatment) Postinfarction Ventricular Septal Rupture Treatment & Management: Medical Therapy, Surgical Therapy, Interventional Therapy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) Controversy surrounds the issue of whether to perform CABG in patients undergoing emergency postinfarction VSR repair. Some authors have found no benefit to CABG in this setting and have concluded that cardiac catheterization in ill patients is time-consuming and poses a risk of contrast injury to the kidney. Others, however, have used a selective approach to cardiac catheterization. In patients who probably do not have a history of or previous myocardial infarction (MI), cardiac catheterization

2014 eMedicine Surgery

129. Ventricular Septal Rupture Following Myocardial Infarction (Follow-up)

Ventricular Septal Rupture Following Myocardial Infarction (Follow-up) Postinfarction Ventricular Septal Rupture Treatment & Management: Medical Therapy, Surgical Therapy, Interventional Therapy Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) Controversy surrounds the issue of whether to perform CABG in patients undergoing emergency postinfarction VSR repair. Some authors have found no benefit to CABG in this setting and have concluded that cardiac catheterization in ill patients is time-consuming and poses a risk of contrast injury to the kidney. Others, however, have used a selective approach to cardiac catheterization. In patients who probably do not have a history of or previous myocardial infarction (MI), cardiac catheterization

2014 eMedicine Surgery

130. Myocardial Infarction (Diagnosis)

Myocardial Infarction (Diagnosis) Myocardial Infarction: Practice Essentials, Background, Definitions Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTU1OTE5LW92ZXJ2aWV3 processing > Myocardial Infarction Updated (...) : Jul 19, 2018 Author: A Maziar Zafari, MD, PhD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Myocardial Infarction Overview Practice Essentials Myocardial infarction (MI) (ie, heart attack) is the irreversible death (necrosis) of heart muscle secondary to prolonged lack of oxygen supply (ischemia). Approximately 1.5 million cases of MI occur annually in the United States. See the images below. Acute myocardial infarction, reperfusion type. In this case

2014 eMedicine.com

131. Myocardial Infarction (Treatment)

adjunctive use of GP II b /III a inhibitors is not recommended but may be considered in selected cases. [ , ] Previous Next: Non-ST-Elevation (NSTE) ACS Key points in the management of patients with non–ST-elevation acute coronary syndrome (NSTE-ACS) (unstable angina and non-STE myocardial infarction [NSTEMI]) is early evaluation and assessment of hemodynamic and electrical stability, estimatation of the overall risk in these patients, and guidance of therapy. There are two alternative management (...) or bivalirudin), as fondaparinux is associated with a higher risk of catheter thrombosis; this was demonstrated in the Fifth Organization to Assess Strategies in Ischemic Syndromes (OASIS-5) trial. [ , , ] Previous Next: Additional Aspects of Management and Late Hospital Care After the initial management and stabilization of the patient in the early and critical phase of acute myocardial infarction (MI), the goals of care for these patients is to restore normal activities, prevent long-term complications

2014 eMedicine Emergency Medicine

132. Myocardial Infarction (Overview)

Myocardial Infarction (Overview) Myocardial Infarction: Practice Essentials, Background, Definitions Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTU1OTE5LW92ZXJ2aWV3 processing > Myocardial Infarction Updated (...) : Jul 19, 2018 Author: A Maziar Zafari, MD, PhD; Chief Editor: Eric H Yang, MD Share Email Print Feedback Close Sections Sections Myocardial Infarction Overview Practice Essentials Myocardial infarction (MI) (ie, heart attack) is the irreversible death (necrosis) of heart muscle secondary to prolonged lack of oxygen supply (ischemia). Approximately 1.5 million cases of MI occur annually in the United States. See the images below. Acute myocardial infarction, reperfusion type. In this case

2014 eMedicine Emergency Medicine

133. Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization Full Text available with Trip Pro

Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization Myocardial ischemia/reperfusion (I/R) injury is a major clinical problem leading to cardiac dysfunction and myocyte death. It is widely held that I/R causes damage to membrane phospholipids, and is a significant mechanism of cardiac I/R injury. Molecular dissection of sarcolemmal damage in I/R, however, has been difficult to address experimentally. We studied here (...) stabilization of adult cardiac myocytes did not affect the status of myocyte-generated oxidants or lipid peroxidation in two independent assays. We also investigated the loss of sarcolemmal integrity using two independent genetic mouse models, dystrophin-deficient mdx or dysferlin knockout (Dysf KO) mice. Both models of sarcolemmal loss-of-function were severely affected by I/R injury ex vivo, and this was lessened by CSS. In vivo studies also showed that infarct size was significantly reduced in CSS

2013 Journal of Molecular and Cellular Cardiology

134. Multiparametric CMR Imaging of Infarct Remodeling in a Percutaneous Reperfused Yucatan Mini-pig Model Full Text available with Trip Pro

mass on Day 2), which led to significant adverse myocardial remodeling that stabilized beyond 30 days. Native T1 values did not reliably differentiate remote and infarct regions acutely. There was no evidence of remote fibrosis as indicated by partition coefficient and collagen fraction analyses. The infarct T2 values remained elevated up to 60 days after MI. Multiparametric CMR in this model showed significant adverse ventricular remodeling 30 days after MI similar to that seen in humans (...) Multiparametric CMR Imaging of Infarct Remodeling in a Percutaneous Reperfused Yucatan Mini-pig Model To further understanding of the temporal evolution and pathophysiology of adverse ventricular remodeling over the first 60 days following a myocardial infarction (MI) in both the infarcted and remote myocardium, we performed multi-parametric cardiac magnetic resonance (CMR) imaging in a closed-chest chronic Yucatan mini-pig model of reperfused MI. Ten animals underwent 90 min left anterior

2017 NMR in Biomedicine

135. A Single Injection of Protein-loaded Coacervate-Gel Significantly Improves Cardiac Function Post Infarction Full Text available with Trip Pro

A Single Injection of Protein-loaded Coacervate-Gel Significantly Improves Cardiac Function Post Infarction After myocardial infarction (MI), the heart undergoes fibrotic pathological remodeling instead of repair and regeneration. With multiple pathologies developing after MI, treatment using several proteins is expected to address this range of pathologies more effectively than a single-agent therapy. A factorial design of experiments study guided us to combine three complementary factors (...) in one injection: tissue inhibitor of metalloproteinases-3 (TIMP-3) was embedded in a fibrin gel for signaling in the initial phase of the treatment, while basic fibroblast growth factor (FGF-2) and stromal cell-derived factor 1-alpha (SDF-1α) were embedded in heparin-based coacervates for sustained release and distributed within the same fibrin gel to exert their effects over a longer period. The gel was then tested in a rat model of myocardial infarction. Contractility of rat hearts treated

2017 Biomaterials

136. A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction. Full Text available with Trip Pro

A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction. Epoxyeicosatrienoic acids (EETs) are natural angiogenic mediators regulated by soluble epoxide hydrolase (sEH). Inhibitors of sEH can stabilize EETs levels and were reported to reduce atherosclerosis and inhibit myocardial infarction in animal models. In this work, we investigated whether increasing EETs with the sEH (...) inhibitor t-AUCB would increase angiogenesis related function in endothelial progenitor cells (EPCs) from patients with acute myocardial infarction (AMI).EPCs were isolated from 50 AMI patients and 50 healthy subjects (control). EPCs were treated with different concentrations of t-AUCB for 24h with or without peroxisome proliferator activated receptor γ (PPARγ) inhibitor GW9662. Migration of EPCs was assayed in trans-well chambers. Angiogenesis assays were performed using a Matrigel-Matrix in vitro

2013 International journal of cardiology

137. Evolution of ventricular tachycardia and its electrophysiological substrate early after myocardial infarction: an ovine model. Full Text available with Trip Pro

Evolution of ventricular tachycardia and its electrophysiological substrate early after myocardial infarction: an ovine model. Sudden arrhythmic death after myocardial infarction (MI) is most frequent in the first month. Early programmed ventricular stimulation (within 1 week) post-MI has been able to identify long-term ventricular tachycardia (VT) occurrence. We aimed to determine the timing of development and stabilization of VT circuits after MI and how the evolution of the underlying (...) sites of VT as well as voltage and velocity substrate on day 8 predicted those on day 100 postinfarct, indicating early formation and stabilization of the arrhythmogenic substrate. VT inducibility was influenced by the distribution of conducting channels and increased complex fractionated signals.

2013 Circulation. Arrhythmia and electrophysiology

138. Changes in reperfusion strategy over time for ST segment elevation myocardial infarction in the Greater Paris Area: results from the e-MUST Registry. (Abstract)

Changes in reperfusion strategy over time for ST segment elevation myocardial infarction in the Greater Paris Area: results from the e-MUST Registry. ESC guidelines recommend a shorter (90 min) delay for the use of primary percutaneous intervention (pPCI) in patients presenting within the first 2h of pain onset. Using registry data on STEMI patients in the Greater Paris Area, we assessed changes between 2003 and 2008 in the rates of pPCI, pre-hospital fibrinolytic therapy (PHF) and time delays (...) in all regions, balanced by a decrease in PHF. The rate of late pPCI remained globally stable, with a decrease in Paris, stabilization in the small ring, and an increase in the large ring, where the density of catheterization laboratories was the lowest. By multivariate analysis, using on-time pPCI as a reference group, mortality was higher in the PHF and late pPCI groups.In areas with a low density of pPCI centers, efforts should be made to improve the timeliness of pPCI. Otherwise, PHF followed

2013 International journal of cardiology

139. Feasibility limits of transradial primary percutaneous coronary intervention in acute myocardial infarction in the real life (TRAP-AMI). Full Text available with Trip Pro

Feasibility limits of transradial primary percutaneous coronary intervention in acute myocardial infarction in the real life (TRAP-AMI). There is growing evidence that transradial (TRI) as compared to transfemoral (TFI) percutaneous coronary intervention (PCI) is associated with improved clinical outcome driven by less hemorrhagic complications, in particular in STEMI patients receiving aggressive antithrombotic treatment. Feasibility rate of TRI in STEMI patients has not yet been (...) ease of radial puncture "probably difficult/impossible" and no TRI attempt was performed (primary TFI). In the 447 patients with TRI attempt, TRI failure requiring switch to TFI (secondary TFI) was necessary in 22 patients (4.7% of total) following radial puncture failure (n=15), dissection of the radial artery (n=1), prohibitive tortuosities or stenosis of the upper limb axis (n=2), or non-selective position or lack of stability of the guiding catheter (n=2). After the start of the angioplasty

2013 International journal of cardiology

140. [LINKOR: results of observational program in patients with myocardial infarction]. (Abstract)

[LINKOR: results of observational program in patients with myocardial infarction]. The results of Assessment Program effective treatment of patients with myocardiaL INfarction drug ProCORalan (ivabradine) in outpatient practice, conducted in 53 cities of the Russian Federation, 333 doctors. Included 1226 patients (822 men and 404 women, average age 60,1+/-9,3 years). Despite treatment, before inclusion in the patients maintained an average 8,17+/-8,60 (mediana 6) angina attacks per week (...) estimated by Seattle Angina Questionnaire and Minnesota Living with Heart Failure. The maximum recommended dose ivabradine of 15mg/day were given 50% of the patients, the dose of 10 mg/day - 28%. Adverse effects were reported in 3.3% of patients, of which, according to doctors associated with taking the drug - 0.82%. During follow up, 4 patients died. Thus, the addition of ivabradine to -blocker therapy, persons with a history of myocardial infarction and angina experiencing elevated heart rate

2013 Kardiologiia Controlled trial quality: uncertain

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