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Mycosis Fungoides

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121. Complete resolution of mycosis fungoides tumors with imiquimod 5% cream: a case series. (PubMed)

Complete resolution of mycosis fungoides tumors with imiquimod 5% cream: a case series. To demonstrate the clinical efficacy of topical 5% imiquimod for mycosis fungoides (MF) tumors.Treatment of tumor-stage MF represents a therapeutic challenge because of a limited number of effective topical therapies. Single tumors can be treated with localized radiation but may recur. Systemic therapies are also an option but are associated with serious adverse effects. Imiquimod is a topical agent whose

2017 Journal of Dermatological Treatment

122. CD8<sup>+</sup> mycosis fungoides: A low-grade lymphoproliferative disorder. (PubMed)

CD8+ mycosis fungoides: A low-grade lymphoproliferative disorder. The prognosis of the CD8+ subtype of mycosis fungoides (MF) is controversial. Although most authors believe that determining the presence of this cell surface antigen has no prognostic value, others have observed a more indolent course for CD8+ MF compared with CD4+ MF.To review the cases of CD8+ MF in the pediatric and adult populations seen at our institution.This is a retrospective review of clinical and pathologic

2017 Journal of American Academy of Dermatology

123. Racial disparity in mycosis fungoides: An analysis of 4495 cases from the US National Cancer Database. (PubMed)

Racial disparity in mycosis fungoides: An analysis of 4495 cases from the US National Cancer Database. Studies have shown contradictory results regarding the survival outcomes among white, African American, and Asian patients with mycosis fungoides (MF).To evaluate the survival outcomes among white, African American, and Asian patients with MF and to determine other prognostic factors of the disease.The US National Cancer Database was used to identify patients with histologically confirmed MF

2017 Journal of American Academy of Dermatology

124. The Effect of Phototherapy on Progression to Tumors in Patients with Patch and Plaque Stage of Mycosis Fungoides. (PubMed)

The Effect of Phototherapy on Progression to Tumors in Patients with Patch and Plaque Stage of Mycosis Fungoides. Phototherapy has been a mainstay in the treatment of mycosis fungoides (MF). However, the recent findings of UV-induced p53 mutations in advanced MF suggest that phototherapy may contribute to disease progression.The objective of this study was to evaluate the effect of phototherapy on the time to tumor progression and overall survival in MF.Retrospective analysis of patients seen

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2017 Journal of Dermatological Treatment

125. Multiple skin cancers in patients with mycosis fungoides after long-term ultraviolet phototherapy. (PubMed)

Multiple skin cancers in patients with mycosis fungoides after long-term ultraviolet phototherapy. Phototherapy is a useful noninvasive therapy, but it can induce cutaneous malignant tumours, including squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). We report on a 79-year-old man who had long-standing mycosis fungoides for 40 years, which had been treated with psoralen ultraviolet A therapy for 37 years at a dose of approximately 5000 J/cm2 . Approximately 6 years before

2017 Clinical & Experimental Dermatology

126. Computed Tomography scanning in mycosis fungoides - optimising the balance between benefit and harm. (PubMed)

Computed Tomography scanning in mycosis fungoides - optimising the balance between benefit and harm. 28498608 2018 12 20 1365-2133 178 2 2018 02 The British journal of dermatology Br. J. Dermatol. Computed tomography scanning in mycosis fungoides: optimizing the balance between benefit and harm. 563-564 10.1111/bjd.15657 Spencer A A 0000-0003-3386-8458 Department of Dermatology, University Hospitals Birmingham, Mindelsohn Way, Edgbaston, Birmingham B15 2GW, U.K. Gazzani P P Department

2017 British Journal of Dermatology

127. Folliculotropic Mycosis Fungoides with Skewed T-cell Receptor CDR3 motif: Suggestive of Lipid Antigen-selection? (PubMed)

Folliculotropic Mycosis Fungoides with Skewed T-cell Receptor CDR3 motif: Suggestive of Lipid Antigen-selection? Folliculotropic mycosis fungoides (FMF), a variant of mycosis fungoides (MF) with distinct clinical features, is characterized by infiltration of malignant T cells in hair follicles. This raises the hypothesis that antigens in the hair follicle may contribute to the pathogenesis of FMF. T-cell receptor β gene (TRB) sequences as well as dendritic cell subsets in patients with FMF (n

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2017 Acta Dermato-Venereologica

128. Tumor-stage mycosis fungoides regressing with milia and pustules after total skin electron beam therapy. (PubMed)

Tumor-stage mycosis fungoides regressing with milia and pustules after total skin electron beam therapy. 28557155 2017 10 23 1468-3083 31 10 2017 Oct Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Tumour-stage mycosis fungoides regressing with milia and pustules after total skin electron beam therapy. e440 10.1111/jdv.14372 Puiu T T University of Michigan Medical School, Ann Arbor, 48103, MI, USA. Porto D A DA Department of Dermatology, Henry

2017 Journal of the European Academy of Dermatology and Venereology

129. Psoriasis in patients with Mycosis Fungoides: Α clinicopathological study of 25 patients. (PubMed)

Psoriasis in patients with Mycosis Fungoides: Α clinicopathological study of 25 patients. It has been reported that patients with psoriasis are at increased risk for developing lymphoma including cutaneous T-cell lymphomas (CTCL). However, the comorbidity and the histopathologic correlation of psoriasis and mycosis fungoides (MF) have been less studied.The objective of this study was to investigate the relation between MF and psoriasis.We retrospectively reviewed and re-evaluated all MF cases

2017 Journal of the European Academy of Dermatology and Venereology

130. The role of macrophages in the pathogenesis of mycosis fungoides. (PubMed)

The role of macrophages in the pathogenesis of mycosis fungoides. Macrophages are classified into classically activated (M1) and alternatively activated (M2) macrophages. Decrease in macrophage number in tumour tissue with treatment has been reported.The aim of this study was to determine whether treatment has an effect on the number of dermal M1 and M2 macrophages in patients with mycosis fungoides (MF).In total, 21 patients (8 women, 13 men; age range 42-73 years) were included in this study

2017 Clinical & Experimental Dermatology

131. Ultraviolet A1 Phototherapy in the Treatment of Early Mycosis Fungoides. (PubMed)

Ultraviolet A1 Phototherapy in the Treatment of Early Mycosis Fungoides. Phototherapy has been the mainstay of therapies for early mycosis fungoides (MF). The beneficial role of ultraviolet (UV) light on MF is suggested by the observation that lesions occur on non-sun-exposed areas. Therapeutic light sources that are available today are broadband UVB, psoralen and UVA, narrowband UVB, and long-wave UV (UVA1). Current literature provides increasing evidence on the use of UVA1 to treat MF.To

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2017 Dermatology

132. Evaluation of O6-Benzylguanine-Potentiated Topical Carmustine for Mycosis Fungoides: A Phase 1-2 Clinical Trial. (PubMed)

Evaluation of O6-Benzylguanine-Potentiated Topical Carmustine for Mycosis Fungoides: A Phase 1-2 Clinical Trial. In a phase 1 trial, single-dose O6-benzylguanine with topical carmustine for patients with early stage (stage IA through stage IIA) cutaneous T-cell lymphoma, mycosis fungoides (MF) type, resulted in clinical responses proportional to inhibition of O6-alkylguanine-DNA alkyltransferase activity, but a maximum tolerated dose (MTD) was not reached.To determine whether dose escalation

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2017 JAMA dermatology (Chicago, Ill.)

133. High Expression of Fas/CD95 on CD4+ Circulating T-cells: An Exclusion Criterion in the Diagnosis of Mycosis Fungoides? (PubMed)

High Expression of Fas/CD95 on CD4+ Circulating T-cells: An Exclusion Criterion in the Diagnosis of Mycosis Fungoides? The aim of this 10-year monocentric prospective study was to determine a cut-off value of Fas/CD95 expression by peripheral blood CD4+ T lymphocytes in discriminating patients with mycosis fungoides from controls with cutaneous benign lymphocytic conditions. CD95 expression in peripheral blood CD4+ T lymphocytes was measured using flow cytometry in 330 patients referred (...) for diagnosis: 104 with mycosis fungoides and 226 with eczema, psoriasis, drug reaction, etc. The sensitivity and specificity of different thresholds of CD95 expression were calculated regarding the final diagnosis of patients with mycosis fungoides or controls. CD95 expression higher than 30% reached a specificity of 91% in ruling out a diagnosis of mycosis fungoides, although overall CD95 expression was not significantly different from that of controls (p = 0.309) and sensitivity was very low (5%). Thus

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2017 Acta Dermato-Venereologica

136. Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report. (PubMed)

Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report. 28218332 2018 03 16 2018 03 16 1651-2057 97 6 2017 06 09 Acta dermato-venereologica Acta Derm. Venereol. Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report. 747-748 10.2340/00015555-2638 Shirai Takushi T Department of Dermatology, Shinshu University School of Medicine,, 3908621 Matsumoto, Japan. Kiniwa Yukiko Y Asaka Shiho S Shimojo Yasuyo Y Kamijo Fuminao F Okuyama Ryuhei R eng Case Reports Journal (...) Article Sweden Acta Derm Venereol 0370310 0001-5555 0 MUC1 protein, human 0 Mucin-1 IM Female Humans Immunohistochemistry Middle Aged Mucin-1 analysis Mycosis Fungoides chemistry Skin Neoplasms chemistry 2017 2 22 6 0 2018 3 17 6 0 2017 2 21 6 0 ppublish 28218332 10.2340/00015555-2638

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2017 Acta Dermato-Venereologica

137. Risk Factors for Skin Infections in Mycosis Fungoides. (PubMed)

Risk Factors for Skin Infections in Mycosis Fungoides. Mycosis fungoides (MF) is the most frequent type of primary cutaneous natural killer and T-cell lymphoma. MF-required immunosuppressive therapies and MF-related immunosuppressive characteristics render patients with MF more prone to infections.To describe the clinical features of cutaneous infections observed in MF patients.A series of 56 MF patients were followed prospectively over 3 years and screened for cutaneous infections.Prospective

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2017 Dermatology

138. Unilesional plantar mycosis fungoides treated with topical photodynamic therapy - case report and review of the literature. (PubMed)

Unilesional plantar mycosis fungoides treated with topical photodynamic therapy - case report and review of the literature. Unilesional mycosis fungoides (UMF) and pagetoid reticulosis (PR) are variants of mycosis fungoides. Conventional therapy comprises surgical excision or radiotherapy, which may be associated with long-term side effects, especially when the lesion is located at a special site like the palms and soles. Therefore, alternative treatment options are needed to treat solitary

2017 Journal of the European Academy of Dermatology and Venereology

139. Recommendations for treatment in Folliculotropic Mycosis Fungoides: Report of the Dutch Cutaneous Lymphoma Group. (PubMed)

Recommendations for treatment in Folliculotropic Mycosis Fungoides: Report of the Dutch Cutaneous Lymphoma Group. Folliculotropic mycosis fungoides (FMF) is an aggressive variant of mycosis fungoides (MF) and generally less responsive to standard skin-directed therapies (SDTs). Recent studies distinguished indolent (early-stage FMF) and more aggressive (advanced-stage FMF) subgroups. The optimal treatment for both subgroups remains to be defined.To evaluate initial treatment results in patients

2017 British Journal of Dermatology

140. Case report: photo‐onycholysis after PUVA treatment for hypopigmented mycosis fungoides with response to topical steroid (PubMed)

Case report: photo‐onycholysis after PUVA treatment for hypopigmented mycosis fungoides with response to topical steroid Melanin in the nail bed in patients with skin type VI has been suggested to afford some protection against photo-onycholysis. We report a case of a 16-year-old male patient with skin type VI with onycholysis following PUVA treatment for hypopigmented mycosis fungoides. Symptoms resolved with the application of topical steroid.

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2017 Clinical Case Reports

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