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Mycosis Fungoides

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41. Oncogenomic analysis identifies novel biomarkers for tumor stage mycosis fungoides. (PubMed)

Oncogenomic analysis identifies novel biomarkers for tumor stage mycosis fungoides. Patients with mycosis fungoides (MF) developing tumors or extracutaneous lesions usually have a poor prognosis with no cure has so far been available. To identify potential novel biomarkers for MF at the tumor stage, a genomic mapping of 41 cutaneous lymphoma biopsies was used to explore for significant genes.The gene expression profiling datasets of MF were obtained from Gene Expression Omnibus database (GEO

2018 Medicine

42. Dermoscopic patterns of early-stage mycosis fungoides in a Chinese population. (PubMed)

Dermoscopic patterns of early-stage mycosis fungoides in a Chinese population. Early-stage mycosis fungoides (eMF) is a clinical diagnostic challenge because it can mimic inflammatory diseases. Dermoscopy has been reported to be useful in evaluation of eMF in Caucasian patients; however, dermoscopic features of eMF in the Chinese population are lacking.To determine the validity of dermoscopy in the diagnosis and differential diagnosis of eMF in a Chinese population.This was a retrospective

2018 Clinical & Experimental Dermatology

43. Hypopigmented mycosis fungoides: a 20-case retrospective series. (PubMed)

Hypopigmented mycosis fungoides: a 20-case retrospective series. Hypopigmented mycosis fungoides (hMF) is a rare subtype of mycosis fungoides. The aim of this study was to identify the clinical-epidemiological profile of our patient group and also to provide additional information about treatment responses and prognosis.This is a cross-sectional retrospective observational study, with exploratory analysis. The outcome variables were disease progression and related death.Twenty patients with hMF

2018 International Journal of Dermatology

44. Mycosis fungoides in a 15-year-old adolescent (PubMed)

Mycosis fungoides in a 15-year-old adolescent 29785329 2018 11 14 2160-9381 8 2 2018 Apr Dermatology practical & conceptual Dermatol Pract Concept Mycosis fungoides in a 15-year-old adolescent. 123-125 10.5826/dpc.0802a10 Estelmann Sarah S Department of Dermatology, Venereology, and Allergology; University Medical Center, Ruprecht-Karls University, Heidelberg, Germany. Neuberger Anna A Department of Dermatology, Venereology, and Allergology; University Medical Center, Ruprecht-Karls University (...) of Dermatology, Venereology, and Allergology; University Medical Center, Ruprecht-Karls University, Heidelberg, Germany. eng Journal Article 2018 04 30 United States Dermatol Pract Concept 101585990 2160-9381 adolescent childhood mycosis fungoides Competing interests: The authors have no conflicts of interest to disclose. 2017 11 12 2017 12 12 2018 5 23 6 0 2018 5 23 6 0 2018 5 23 6 1 epublish 29785329 10.5826/dpc.0802a10 dp0802a10 PMC5955079 J Am Acad Dermatol. 2014 Dec;71(6):1117-26 25264240 Eur J Cancer

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2018 Dermatology practical & conceptual

45. Occurrence of Mycosis Fungoides in an Iranian Chemical Victim of the Iran-Iraq War with a Long-term Follow-Up: A Case Report and Review of Literature (PubMed)

Occurrence of Mycosis Fungoides in an Iranian Chemical Victim of the Iran-Iraq War with a Long-term Follow-Up: A Case Report and Review of Literature Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Persistent antigenic stimulation has been claimed to play a role in the development of this malignancy. We aimed to show the role of sulfur mustard in the pathogenesis of MF. A 45-year-old man with MF is introduced herein. He was a victim of chemical exposure in 1987

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2018 Iranian journal of medical sciences

46. Early morphea simulating patch-stage mycosis fungoides in two cases (PubMed)

Early morphea simulating patch-stage mycosis fungoides in two cases Morphea is a skin disorder characterized by thickening of dermis and subcutaneous tissues and loss of adnexal structures. In the early inflammatory stage of morphea, diagnostic histological findings are absent and this may lead to confusion with other inflammatory dermatoses such as mycosis fungoides (MF). We report two cases of early stage morphea mimicking patchstage of MF. Histopathologic examination of biopsies obtained

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2018 Dermatology Reports

47. Bone marrow suppression as a complication of total skin helical tomotherapy in the treatment of mycosis fungoides (PubMed)

Bone marrow suppression as a complication of total skin helical tomotherapy in the treatment of mycosis fungoides Total skin electron beam therapy (TSEBT) is an effective treatment in mycosis fungoides. Total skin helical tomotherapy (TSHT) may be an alternative to TSEBT and may offer several dosimetric and treatment advantages. There are currently very few published treatment results using TSHT in place of TSEBT for treatment of mycosis fungoides.Two patients with mycosis fungoides were (...) had been treated for mycosis fungoides using helical tomotherapy (HT) at a dose of 20 Gy to a localized region and experienced mild thrombocytopenia at that time. The patient then underwent retreatment 17 months later with TSHT to a dose of 12 Gy in 6 fractions with a mean bone marrow dose of 2.3 Gy and V10 = 4.28%. This patient once again experienced myelosuppression that included grade 4 thrombocytopenia. She also required blood and platelet transfusions.Both patients treated with TSHT

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2018 Radiation oncology (London, England)

48. Synchronous Occurrence of Mycosis Fungoides, Diffuse Large B Cell Lymphoma and Acute Myeloid Leukemia (PubMed)

Synchronous Occurrence of Mycosis Fungoides, Diffuse Large B Cell Lymphoma and Acute Myeloid Leukemia Patients with mycosis fungoides (MF), the most common subtype of primary cutaneous T-cell lymphoma, have an increased risk of developing secondary malignancies. We herein report two rare cases of MF concurring with diffuse large B cell lymphoma (B lymphoid lineage) and acute myeloid leukemia (myeloid lineage) in two otherwise healthy elderly patients. Potential etiologic factors, including

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2018 Internal Medicine

49. Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy (PubMed)

Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy Mogamulizumab induces cytotoxicity against CCR4+ lymphoma cells by antibody-dependent cell-mediated cytotoxicity in advanced cutaneous T-cell lymphoma patients. Since the efficacy of mogamulizumab in mycosis fungoides (28.6%) is lower than that in Sézary syndrome (47.1%), reagents that enhance the antitumor immune response induced by mogamulizumab are needed to further optimize its use (...) for the treatment of erythrodermic mycosis fungoides. In this report, we present a case of erythrodermic mycosis fungoides successfully treated with mogamulizumab followed by etoposide monotherapy.

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2018 Case reports in oncology

50. Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data (PubMed)

Clinical potential of mechlorethamine gel for the topical treatment of mycosis fungoides-type cutaneous T-cell lymphoma: a review on current efficacy and safety data Nitrogen mustard is a chemotherapeutic agent that has a well-documented safety and efficacy profile in the treatment of cutaneous T-cell lymphoma. Development of nitrogen mustard formulations and treatment regimens has been studied extensively over the last 40 years. In the last 5 years, a new gel formulation has been developed

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2018 Drug design, development and therapy

51. A unique combination of Rosai-Dorfman disease and mycosis fungoides: a case report (PubMed)

A unique combination of Rosai-Dorfman disease and mycosis fungoides: a case report Rosai-Dorfman disease (RDD) is a rare histiocytic condition of unknown etiology. Patients with RDD classically present with massive painless cervical lymphadenopathy. However, extra-nodal disease occurs in approximately 40% of cases, with the skin being among the most commonly involved sites. Patients with isolated extra-nodal involvement may present without adenopathy. Reports of RDD occurring in patients (...) with Hodgkin's lymphoma, and B-cell lymphoma have been published, but there has only been one previous report of RDD in a patient with a T-cell lymphoma. This case report documents a unique combination of RDD and mycosis fungoides (MF), a cutaneous T cell lymphoma. This report also highlights diagnostic challenges in RDD due to the rarity of the condition and its variable presentation.

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2018 SAGE Open Medical Case Reports

52. A case of acute heart failure due to myocardial infiltration of mycosis fungoides (PubMed)

A case of acute heart failure due to myocardial infiltration of mycosis fungoides Mycosis fungoides (MF) has been reported to be the most common cutaneous lymphoma with a good prognosis and myocardial infiltration is clinically rare. We hereby report a case of rapidly progressing acute heart failure due to myocardial infiltration by MF. Perfusion cardiac magnetic resonance imaging (MRI) demonstrated a massive perfusion defect in the left ventricle (LV) where multiple nodular enhancement areas (...) by delayed enhancement MRI could be documented in the postero-lateral wall of the LV, which resulted in a deterioration of the LV function and mitral regurgitation. Autopsy confirmed the myocardial infiltration by the MF, which corresponded with the MRI findings. mycosis fungoides (MF) have a poor prognosis because they could not undergo chemotherapy for primary disease. Therefore, early diagnosis is important

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2018 Journal of cardiology cases

53. Total Skin Electron Beam Therapy with Rotary Dual Technique as Palliative Treatment for Mycosis Fungoides (PubMed)

Total Skin Electron Beam Therapy with Rotary Dual Technique as Palliative Treatment for Mycosis Fungoides The aim of the study was to retrospectively assess the efficacy and toxicity of total skin electron beam therapy (TSEBT) in patients with primary cutaneous T-cell lymphoma (MF, mycosis fungoides) at various stages of development.Treatment results of 40 patients with MF stage IB-III, treated between 2001 and 2015, were reviewed. Median total dose was 32 Gy, delivered to the entire skin

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2018 In Vivo

54. The importance of lymph node examination: Simultaneous diagnosis of hypopigmented mycosis fungoides and follicular B-cell lymphoma (PubMed)

The importance of lymph node examination: Simultaneous diagnosis of hypopigmented mycosis fungoides and follicular B-cell lymphoma 29942830 2019 02 26 2352-5126 4 6 2018 Jul JAAD case reports JAAD Case Rep The importance of lymph node examination: Simultaneous diagnosis of hypopigmented mycosis fungoides and follicular B-cell lymphoma. 590-592 10.1016/j.jdcr.2018.05.017 Joseph Mathew X MX Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia. Brown Ashley D (...) AD Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia. Davis Loretta S LS Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia. eng Case Reports 2018 06 19 United States JAAD Case Rep 101665210 2352-5126 CTCL, cutaneous T-cell lymphoma MF, mycosis fungoides NHL, non-Hodgkin lymphoma bcl, B-cell lymphoma gene cutaneous T-cell lymphoma follicular B-cell lymphoma mycosis fungoides simultaneous diagnosis 2018 6 27 6 0

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2018 JAAD Case Reports

55. Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome

Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one (...) or more studies before adding more. Pembrolizumab and Total Skin Electron Beam Radiotherapy in Mycosis Fungoides and Sézary Syndrome The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03617224 Recruitment Status : Recruiting

2018 Clinical Trials

56. Ultra Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides

Ultra Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides Ultra Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ultra (...) Low Dose Radiation for Local Treatment of Cutaneous Mycosis Fungoides The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03398161 Recruitment Status : Recruiting First Posted : January 12, 2018 Last Update Posted : August

2018 Clinical Trials

57. Dosing of Brentuximab Vedotin for Mycosis Fungoides Patients

Dosing of Brentuximab Vedotin for Mycosis Fungoides Patients Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Dosing (...) of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03587844 Recruitment Status : Recruiting First Posted : July 16, 2018 Last Update Posted : February 15, 2019

2018 Clinical Trials

58. SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides

SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (...) (100). Please remove one or more studies before adding more. SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides (SOLAR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2018 Clinical Trials

59. Folliculotropic CD8+ mycosis fungoides associated with diffuse mucosal involvement (PubMed)

Folliculotropic CD8+ mycosis fungoides associated with diffuse mucosal involvement 30246124 2019 02 26 2352-5126 4 8 2018 Sep JAAD case reports JAAD Case Rep Folliculotropic CD8 + mycosis fungoides associated with diffuse mucosal involvement. 777-779 10.1016/j.jdcr.2018.04.005 de Masson Adèle A Dermatologie, Höpital Saint-Louis, APHP, Paris, France. Université Paris Diderot, Paris, France. Frumholtz Laure L Dermatologie, Höpital Saint-Louis, APHP, Paris, France. Battistella Maxime M Université (...) , Paris, France. Université Paris Diderot, Paris, France. Cordoliani Florence F Dermatologie, Höpital Saint-Louis, APHP, Paris, France. eng Case Reports 2018 09 14 United States JAAD Case Rep 101665210 2352-5126 CD8 FMF, folliculotropic mycosis fungoides MF, mycosis fungoides TRM, resident memory T cells folliculotropism mucosa mycosis fungoides 2018 9 25 6 0 2018 9 25 6 0 2018 9 25 6 1 epublish 30246124 10.1016/j.jdcr.2018.04.005 S2352-5126(18)30105-X PMC6141727 J Exp Med. 2010 Mar 15;207(3):553-64

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2018 JAAD Case Reports

60. Commentary to “Mogamulizumab‐induced photosensitivity in patients with mycosis fungoides and other T‐cell neoplasms” by Y. Masuda et al. (PubMed)

Commentary to “Mogamulizumab‐induced photosensitivity in patients with mycosis fungoides and other T‐cell neoplasms” by Y. Masuda et al. 30303306 2018 12 07 1468-3083 32 10 2018 Oct Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Commentary to "Mogamulizumab-induced photosensitivity in patients with mycosis fungoides and other T-cell neoplasms" by Y. Masuda et al. 1626 10.1111/jdv.15214 Hönigsmann H H Department of Dermatology

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2018 Journal of the European Academy of Dermatology and Venereology

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