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Mycosis Fungoides

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181. Mycosis Fungoides and the Sézary Syndrome Treatment (PDQ®): Health Professional Version

Mycosis Fungoides and the Sézary Syndrome Treatment (PDQ®): Health Professional Version Mycosis Fungoides (Including Sézary Syndrome) Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ (...) Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002-. Search term Mycosis Fungoides (Including Sézary Syndrome) Treatment (PDQ®) Health Professional Version PDQ Adult Treatment Editorial Board . Published online: September 20, 2019. This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of mycosis fungoides (including Sézary Syndrome). It is intended as a resource to inform and assist clinicians who

2016 PDQ - NCI's Comprehensive Cancer Database

182. Hypopigmented Mycosis Fungoides versus Mycosis Fungoides with Concomitant Hypopigmented Lesions: Same Disease or Different Variants of Mycosis Fungoides? (Abstract)

Hypopigmented Mycosis Fungoides versus Mycosis Fungoides with Concomitant Hypopigmented Lesions: Same Disease or Different Variants of Mycosis Fungoides? Hypopigmented mycosis fungoides (HMF) is a rare subtype of mycosis fungoides (MF). We compared patients with exclusive hypopigmented lesions with a group of MF patients with concomitant different lesions.20 patients with HMF only and 14 patients with hypopigmented lesions concomitant with other types of lesions (mixed MF, MMF) were selected

2014 Dermatology

183. Adult pityriasis lichenoides-like mycosis fungoides: a clinical variant of mycosis fungoides. (Abstract)

Adult pityriasis lichenoides-like mycosis fungoides: a clinical variant of mycosis fungoides. Mycosis fungoides (MF) is the most frequent type of cutaneous T cell lymphoma. Its clinicopathological spectrum is wide, and the resulting diversity makes it difficult to establish a differential diagnosis among pityriasis lichenoides (PL), lymphomatoid papulosis (LyP), and atypical MF.This study describes four patients with longstanding PL-like lesions, in whom clinicopathological correlations

2014 International Journal of Dermatology

184. CCR7 expression correlates with subcutaneous involvement in mycosis fungoides skin lesions and promotes migration of mycosis fungoides cells (MyLa) through mTOR activation. (Abstract)

CCR7 expression correlates with subcutaneous involvement in mycosis fungoides skin lesions and promotes migration of mycosis fungoides cells (MyLa) through mTOR activation. The molecular pathogenesis of mycosis fungoides (MF) is currently poorly understood. The chemokine receptor CCR7 has been demonstrated to be involved in the development and progression of certain cancers, but its role in MF has rarely been investigated.We seek to determine whether CCR7 is expressed in MF skin lesions

2014 Journal of dermatological science

185. Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography: Case report and review of literature. Full Text available with Trip Pro

Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography: Case report and review of literature. Mycosis fungoides is a kind of malignant lymphoma arising from T cells, but primarily occurs in skin, and it is the most common type of cutaneous lymphoma. Mycosis fungoides (MF) is a rare non-Hodgkin lymphoma but the most common type of primary cutaneous T-cell lymphomas. Because of unknown etiology and mechanism, and lack of typical clinical

2016 Medicine

186. The biomarker landscape in mycosis fungoides and sézary syndrome. Full Text available with Trip Pro

The biomarker landscape in mycosis fungoides and sézary syndrome. The practice of pre-emptive individualized medicine is predicated on the discovery, development and application of biomarkers in specific clinical settings. Mycosis fungoides and Sézary syndrome are the two most common type of cutaneous T-cell lymphoma, yet diagnosis, prognosis and disease monitoring remain a challenge. In this review, we discuss the current state of biomarker discovery in mycosis fungoides and Sézary syndrome

2016 Experimental Dermatology

187. Topical Carmustine as Monotherapy or as Multimodality Therapy for Folliculotropic Mycosis Fungoides. Full Text available with Trip Pro

Topical Carmustine as Monotherapy or as Multimodality Therapy for Folliculotropic Mycosis Fungoides. 27868149 2017 03 20 2018 11 13 1651-2057 97 3 2017 03 10 Acta dermato-venereologica Acta Derm. Venereol. Topical Carmustine as Monotherapy or as Multimodality Therapy for Folliculotropic Mycosis Fungoides. 373-374 10.2340/00015555-2551 MacArthur Kelly M KM Department of Dermatology, Johns Hopkins University, 601 North Caroline Street, 8 Floor, Baltimore, Maryland, 21287, USA. kmacart1@jhmi.edu (...) Mycosis Fungoides drug therapy pathology Neoplasm Staging Skin Neoplasms drug therapy pathology Time Factors Treatment Outcome 2016 11 22 6 0 2017 3 21 6 0 2016 11 22 6 0 ppublish 27868149 10.2340/00015555-2551 PMC5363058 NIHMS850585 Arch Dermatol. 2002 Feb;138(2):191-8 11843638 Semin Dermatol. 1994 Sep;13(3):202-6 7986689 Acta Derm Venereol. 2013 May;93(3):325-9 23053197 Arch Dermatol. 1972 Aug;106(2):177-82 5048217 J Am Acad Dermatol. 2010 Mar;62(3):418-26 20079954 J Invest Dermatol. 1987 Mar;88(3

2016 Acta Dermato-Venereologica

188. Mycosis fungoides patient accompanied actinic keratosis, actinic keratosis with squamous cell carcinoma transformation, and porokeratosis after NBUVB therapy - 1st case report and review of the literature. Full Text available with Trip Pro

Mycosis fungoides patient accompanied actinic keratosis, actinic keratosis with squamous cell carcinoma transformation, and porokeratosis after NBUVB therapy - 1st case report and review of the literature. Mycosis fungoides (MF) is the most common form of primary cutaneous T cell lymphoma. Narrowband ultraviolet B light (NBUVB) is used increasingly in treating MF because of its good toleration and well-established management.To discuss the risk factors and underlying pathogenic factors

2016 Medicine

189. Mycosis Fungoides two decades after exposure to sulfur mustard: A follow up of 1100 victims. (Abstract)

Mycosis Fungoides two decades after exposure to sulfur mustard: A follow up of 1100 victims. Sulphur mustard (SM) is an alkylating chemical warfare agent which causes acute and chronic injuries to the eyes, skin, lung and respiratory tract.We aimed to investigate the relationship between SM poisoning and Mycosis fungoides (MF) as a late consequence.In this retrospective study, the medical files of 1100 Iranian veterans confirmed to have exposure to SM agent during the Iraq-Iran war of the 1980s

2016 Journal of the European Academy of Dermatology and Venereology

190. Interstitial Mycosis Fungoides: A Clinicopathologic Study of 21 Patients. (Abstract)

Interstitial Mycosis Fungoides: A Clinicopathologic Study of 21 Patients. Interstitial mycosis fungoides (IMF) is a rare histopathologic variant of mycosis fungoides (MF) that may mimic other inflammatory dermatoses, mainly interstitial granuloma annulare, inflammatory morphea, and interstitial granulomatous dermatitis. Only small series and sporadic case reports of IMF have been described in the literature. We reviewed 27 specimens from 21 patients with IMF (M:F=11:10, median age 60) to better

2016 American Journal of Surgical Pathology

191. Clinical Staging and Prognostic Factors in Folliculotropic Mycosis Fungoides. Full Text available with Trip Pro

Clinical Staging and Prognostic Factors in Folliculotropic Mycosis Fungoides. Large case series suggest that patients with folliculotropic mycosis fungoides (FMF) have a worse prognosis than patients with classic mycosis fungoides (MF). However, recent studies described a subgroup of patients with FMF with a more favorable prognosis. Distinction between indolent and aggressive FMF may have important therapeutic consequences but is hampered by the inability of the current tumor-node-metastasis

2016 JAMA dermatology (Chicago, Ill.)

192. The new Cutaneous Lymphoma International Prognostic index (CLIPi) for early mycosis fungoides failed to identify prognostic groups in a cohort of Spanish patients. (Abstract)

The new Cutaneous Lymphoma International Prognostic index (CLIPi) for early mycosis fungoides failed to identify prognostic groups in a cohort of Spanish patients. 26990536 2017 08 22 2017 08 22 1365-2133 175 4 2016 Oct The British journal of dermatology Br. J. Dermatol. The new Cutaneous Lymphoma International Prognostic index (CLIPi) for early mycosis fungoides failed to identify prognostic groups in a cohort of Spanish patients. 794-6 10.1111/bjd.14559 Sanz-Bueno J J Department (...) and over Disease Progression Female Humans Kaplan-Meier Estimate Male Middle Aged Mycosis Fungoides diagnosis mortality Prognosis Risk Assessment methods Severity of Illness Index Skin Neoplasms diagnosis mortality Spain epidemiology Young Adult 2016 3 19 6 0 2016 3 19 6 0 2017 8 23 6 0 ppublish 26990536 10.1111/bjd.14559

2016 British Journal of Dermatology

193. The clinical spectrum of mycosis fungoides in Tanzania, East-Africa. (Abstract)

The clinical spectrum of mycosis fungoides in Tanzania, East-Africa. 27529394 2018 07 09 2018 07 09 1365-2133 176 6 2017 06 The British journal of dermatology Br. J. Dermatol. The clinical spectrum of mycosis fungoides in Tanzania, East Africa. 1653-1656 10.1111/bjd.14963 Grijsen M L ML Departments of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Regional Dermatology Training Centre at Kilimanjaro Christian Medical University College, Moshi, United Republic of Tanzania (...) Methotrexate administration & dosage Middle Aged Mycosis Fungoides drug therapy epidemiology pathology Prednisolone administration & dosage Pruritus epidemiology pathology Skin Neoplasms drug therapy epidemiology pathology Tanzania epidemiology Treatment Outcome Young Adult 2016 8 17 6 0 2018 7 10 6 0 2016 8 17 6 0 ppublish 27529394 10.1111/bjd.14963

2016 British Journal of Dermatology

194. Immunophenotypic shift from CD4<sup>+</sup> to CD8<sup>+</sup> in mycosis fungoides. (Abstract)

Immunophenotypic shift from CD4+ to CD8+ in mycosis fungoides. 27167533 2017 08 22 2017 08 22 1365-2133 175 4 2016 Oct The British journal of dermatology Br. J. Dermatol. Immunophenotypic shift from CD4(+) to CD8(+) in mycosis fungoides. 830-3 10.1111/bjd.14723 Endo C C Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. Naka Y Y Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho (...) , Japan. Tsunemi Y Y Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. ytsun-tky@umin.ac.jp. eng Case Reports Letter 2016 07 27 England Br J Dermatol 0004041 0007-0963 IM CD4-Positive T-Lymphocytes immunology CD8-Positive T-Lymphocytes immunology Humans Immunophenotyping Male Middle Aged Mycosis Fungoides immunology Skin Neoplasms immunology 2016 5 12 6 0 2016 5 12 6 0 2017 8 23 6 0 ppublish 27167533 10.1111/bjd.14723

2016 British Journal of Dermatology

195. STAT3/5 dependent IL-9 overexpression contributes to neoplastic cell survival in mycosis fungoides. Full Text available with Trip Pro

STAT3/5 dependent IL-9 overexpression contributes to neoplastic cell survival in mycosis fungoides. Sustained inflammation is a key feature of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL). Resident IL9-producing T cells have been found in skin infections and certain inflammatory skin diseases, but their role in MF is currently unknown.We analyzed lesional skin from patients with MF for the expression of IL9 and its regulators. To determine which cells were (...) growth, higher frequencies of regulatory T cells, and activated CD4 and CD8 T lymphocytes.Our results suggest that IL9 and its regulators are promising new targets for therapy development in mycosis fungoides. Clin Cancer Res; 22(13); 3328-39. ©2016 AACR.©2016 American Association for Cancer Research.

2016 Clinical Cancer Research

196. Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases. Full Text available with Trip Pro

Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases. Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, Sweden from 1996 to 2010. Forty-four patients with clinically and histopathologically verified MF were identified during the period, with a mean

2016 Acta Dermato-Venereologica

197. Phase II multicentre trial of oral quisinostat, a histone deacetylase inhibitor, in patients with previously treated stage IB-IVA mycosis fungoides/Sézary syndrome. (Abstract)

Phase II multicentre trial of oral quisinostat, a histone deacetylase inhibitor, in patients with previously treated stage IB-IVA mycosis fungoides/Sézary syndrome. Quisinostat is a hydroxamate, second-generation, orally available pan-histone deacetylase inhibitor.To evaluate the efficacy and safety of oral quisinostat in patients with previously treated cutaneous T-cell lymphoma (CTCL).Patients received quisinostat 8 mg or 12 mg on days 1, 3 and 5 of each week in 21-day treatment cycles

2016 British Journal of Dermatology Controlled trial quality: uncertain

198. IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression Full Text available with Trip Pro

IL-32 induces indoleamine 2,3-dioxygenase+CD1c+ dendritic cells and indoleamine 2,3-dioxygenase+CD163+ macrophages: Relevance to mycosis fungoides progression Mycosis fungoides (MF) progresses from patch to tumor stage by expansion of malignant T-cells that fail to be controlled by protective immune mechanisms. In this study, we focused on IL-32, a cytokine, highly expressed in MF lesions. Depending on the other cytokines (IL-4, GM-CSF) present during in vitro culture of healthy volunteers

2016 Oncoimmunology

199. The Therapeutic Potential of AN-7, a Novel Histone Deacetylase Inhibitor, for Treatment of Mycosis Fungoides/Sezary Syndrome Alone or with Doxorubicin Full Text available with Trip Pro

The Therapeutic Potential of AN-7, a Novel Histone Deacetylase Inhibitor, for Treatment of Mycosis Fungoides/Sezary Syndrome Alone or with Doxorubicin The 2 histone deacetylase inhibitors (HDACIs) approved for the treatment of cutaneous T-cell lymphoma (CTCL) including mycosis fungoides/sezary syndrome (MF/SS), suberoylanilide hydroxamic acid (SAHA) and romidepsin, are associated with low rates of overall response and high rates of adverse effects. Data regarding combination treatments

2016 PloS one

200. Correlation between mycosis fungoides and pregnancy Full Text available with Trip Pro

Correlation between mycosis fungoides and pregnancy To evaluate the effect of pregnancy on the natural course of Mycosis fungoides (MF) and compare the obtained results with previous reports.The medical records of 140 patients with cutaneous T-cell lymphoma (CTCL) treated at the University Hospital of Isfahan (the academic referral center for CTCL) Isfahan, Iran. Between 2000 and 2013 were retrospectively reviewed to retrieve all cases of pregnancy during the course of MF disease. A total of 8 (...) pregnancies were recorded. The median age of patients at the time of diagnosis was 26.7 (range 21-30 years) and pregnancy 29.4 (range 27-31 years). Most of patients had early-stage MF (Ia and Ib). All patients experienced aggravation of disease during pregnancy or immediately postpartum. Mycosis fungoides did not cause any complications during pregnancy. Pregnancy appears to have a negative impact on the course of MF, probably due to immune system deteriorations during the pregnancy. Further studies

2016 Saudi medical journal

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