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Mycosis Fungoides

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181. Increasing Numbers of Mast Cells in Skin Lesions of Hyperpigmented Mycosis Fungoides with Large-Cell Transformation (PubMed)

Increasing Numbers of Mast Cells in Skin Lesions of Hyperpigmented Mycosis Fungoides with Large-Cell Transformation 26848231 2016 02 05 2018 11 13 1013-9087 28 1 2016 Feb Annals of dermatology Ann Dermatol Increasing Numbers of Mast Cells in Skin Lesions of Hyperpigmented Mycosis Fungoides with Large-Cell Transformation. 115-6 10.5021/ad.2016.28.1.115 Kondo Mayo M Department of Dermatology, Tokyo Medical and Dental University, Graduate School of Medicine, Tokyo, Japan. Igawa Ken K Department

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2016 Annals of dermatology

182. Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides (PubMed)

Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body

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2016 Case reports in ophthalmological medicine

183. Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides (PubMed)

Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides This study aimed to analyze the predominant expression of the variable region of T cell receptor (TRBV) and determine whether NAV3 or TNFRSF1B gene mutation involved in the pathogenesis of MF.TRBV5-7 expression increased from the normal, early-stage to advanced-stage lesion in MF patient. By contrast, TRBV2 decreased with the lesion developed. We found no mutations

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2016 Oncotarget

184. Reflectance confocal microscopy features of mycosis fungoides and Sézary syndrome: correlation with histopathologic and T-cell receptor rearrangement studies (PubMed)

Reflectance confocal microscopy features of mycosis fungoides and Sézary syndrome: correlation with histopathologic and T-cell receptor rearrangement studies Mycosis fungoides/Sézary syndrome (MF/SS) often requires multiple skin biopsies for definitive diagnosis. In vivo reflectance confocal microscopy (RCM) visualizes high-resolution cellular detail of the skin. The objective of this study is to evaluate the morphologic features of MF/SS using RCM and to correlate RCM features

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2016 Journal of cutaneous pathology

185. Mycosis Fungoides

Mycosis Fungoides Mycosis Fungoides Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Mycosis Fungoides Mycosis Fungoides Aka: Mycosis (...) Associated with superficial and deep Associated with metastases to , lung, GI tract VI. Complications VII. Course Survival <3 years after tumors develop VIII. References Habif (1996) Clinical Dermatology, Mosby, p. 674-5 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Mycosis Fungoides." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Mycosis

2018 FP Notebook

186. Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides (Resimmune®) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT02943642

2016 Clinical Trials

187. Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides

Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoides The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details

2016 Clinical Trials

188. STAT3/5 dependent IL-9 overexpression contributes to neoplastic cell survival in mycosis fungoides. (PubMed)

STAT3/5 dependent IL-9 overexpression contributes to neoplastic cell survival in mycosis fungoides. Sustained inflammation is a key feature of mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL). Resident IL9-producing T cells have been found in skin infections and certain inflammatory skin diseases, but their role in MF is currently unknown.We analyzed lesional skin from patients with MF for the expression of IL9 and its regulators. To determine which cells were (...) growth, higher frequencies of regulatory T cells, and activated CD4 and CD8 T lymphocytes.Our results suggest that IL9 and its regulators are promising new targets for therapy development in mycosis fungoides. Clin Cancer Res; 22(13); 3328-39. ©2016 AACR.©2016 American Association for Cancer Research.

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2016 Clinical Cancer Research

189. Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases. (PubMed)

Mycosis Fungoides: A Retrospective Study of 44 Swedish Cases. Mycosis fungoides (MF) is a primary cutaneous T-cell lymphoma with slow disease progression. There is a lack of descriptive data from Sweden concerning patients with this diagnosis. This study extracted data on patients admitted to the dermatology department at Lund University Hospital, Sweden from 1996 to 2010. Forty-four patients with clinically and histopathologically verified MF were identified during the period, with a mean

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2016 Acta Dermato-Venereologica

190. Prognostic indicators for mycosis fungoides in a Greek population. (PubMed)

Prognostic indicators for mycosis fungoides in a Greek population. Mycosis fungoides (MF) is an indolent cutaneous lymphoma with excellent prognosis at early stages and much poorer outcome during disease progression. Old age, male sex and folliculotropism have been proposed as relevant prognostic factors; however, their exact effect remains debatable.To evaluate MF prognostic indicators and survival rates in a Greek population.Prognostic variables affecting survival rates were studied in 473

2016 British Journal of Dermatology

191. Podoplanin Expression Correlates with Disease Progression in Mycosis Fungoides. (PubMed)

Podoplanin Expression Correlates with Disease Progression in Mycosis Fungoides. The aim of this study was to investigate the role of lymphangiogenesis in the clinical progression and outcome of mycosis fungoides. Immunohistochemistry and Western blot techniques were used to assess the expression of podoplanin and vascular endothelial growth factor C in mycosis fungoides. Expression of vascular endothelial growth factor C measured by immunohistochemistry was significantly higher in mycosis (...) fungoides samples in comparison with control cases (chronic benign dermatoses) (p = 0.0012). Increased expression of podoplanin was found in advanced vs. early mycosis fungoides (p < 0.0001), and was positively correlated with cutaneous and nodal involvement (p < 0.001, p < 0.0001; respectively). Higher podoplanin expression was also significantly associated with shorter survival (p < 0.001). Strong positive correlation was observed between expression of podoplanin analysed by immunohistochemistry

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2016 Acta Dermato-Venereologica

192. Fibrinogen-like Protein 2 Activity as a Potential Biomarker for Diagnosis of Early Mycosis Fungoides. (PubMed)

Fibrinogen-like Protein 2 Activity as a Potential Biomarker for Diagnosis of Early Mycosis Fungoides. 27535237 2017 03 20 2017 05 05 1651-2057 97 3 2017 03 10 Acta dermato-venereologica Acta Derm. Venereol. Fibrinogen-like Protein 2 Activity as a Potential Biomarker for Diagnosis of Early Mycosis Fungoides. 370-372 10.2340/00015555-2514 Sherman Shany S Laboratory for Molecular Dermatology, Felsenstein Medical Research Center, Tel Aviv University, Petach Tikva, Israel. Rabizadeh Esther E Moyal (...) Lilach L Livnat Tami T Ziv Esther E Cherny Izhack I Inbal Aida A Hodak Emmilia E eng Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 0 Biomarkers, Tumor 0 FGL2 protein, human 0 RNA, Messenger 9001-32-5 Fibrinogen IM Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor blood genetics Case-Control Studies Early Detection of Cancer methods Female Fibrinogen analysis genetics Humans Leukocytes, Mononuclear chemistry Linear Models Male Middle Aged Multivariate Analysis Mycosis Fungoides

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2016 Acta Dermato-Venereologica

193. The clinical spectrum of mycosis fungoides in Tanzania, East-Africa. (PubMed)

The clinical spectrum of mycosis fungoides in Tanzania, East-Africa. 27529394 2018 07 09 2018 07 09 1365-2133 176 6 2017 06 The British journal of dermatology Br. J. Dermatol. The clinical spectrum of mycosis fungoides in Tanzania, East Africa. 1653-1656 10.1111/bjd.14963 Grijsen M L ML Departments of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. Regional Dermatology Training Centre at Kilimanjaro Christian Medical University College, Moshi, United Republic of Tanzania (...) Methotrexate administration & dosage Middle Aged Mycosis Fungoides drug therapy epidemiology pathology Prednisolone administration & dosage Pruritus epidemiology pathology Skin Neoplasms drug therapy epidemiology pathology Tanzania epidemiology Treatment Outcome Young Adult 2016 8 17 6 0 2018 7 10 6 0 2016 8 17 6 0 ppublish 27529394 10.1111/bjd.14963

2016 British Journal of Dermatology

194. Hypopigmented mycosis fungoides: a retrospective clinicohistopathologic study. (PubMed)

Hypopigmented mycosis fungoides: a retrospective clinicohistopathologic study. Hypopigmented mycosis fungoides is a rare variant of mycosis fungoides with limited published clinicohistopathologic data available.To characterize our patient group, to provide additional information and insight into this malignancy.A 16-year retrospective medical records review (from 1992 to 2009) was conducted of patients with a diagnosis of hypopigmented mycosis fungoides.All patients were seen in the department (...) , one Afro-Caribbean and one Hispanic. The interval from disease onset to diagnosis ranged from 7 months to 24 years. Patients presented at Stage 1A or 1B. Treatment included phototherapy and topical medications. In four patients with pre- and post-treatment biopsies, the original histological diagnosis of hypopigmented mycosis fungoides and the subsequent complete resolution were shown. There was no associated mortality in the patients studied.Hypopigmented mycosis fungoides affected skin of colour

2016 Journal of the European Academy of Dermatology and Venereology

195. Tumor-associated M2 macrophages in mycosis fungoides acquire immunomodulatory function by interferon alpha and interferon gamma. (PubMed)

Tumor-associated M2 macrophages in mycosis fungoides acquire immunomodulatory function by interferon alpha and interferon gamma. Tumor-associated M2 macrophages (TAMs) produce chemokines that affect the formation of cutaneous T-cell lymphoma (CTCL) by stromal factors. Since IFNs are an effective treatment for advanced-stage mycosis fungoides (MF), we hypothesized that IFNs might modulate M2 macrophages.To prove our hypothesis, we stimulated monocyte-derived M2 macrophages with IFN-α2a or IFN-γ

2016 Journal of dermatological science

196. A Rare Case of Mycosis Fungoides in the Oral Cavity and Small Intestine Complicated by Perforation (PubMed)

A Rare Case of Mycosis Fungoides in the Oral Cavity and Small Intestine Complicated by Perforation Extracutaneous involvement in mycosis fungoides (MF) carries a poor prognosis. Oral and gastrointestinal (GI) tract lesions are both rare locations of disease. We describe the clinical findings of one case with oral and GI MF complicated by perforation after systemic antineoplastic treatment, and review the relevant literature. The patient had a 1-year history of MF before development of tongue

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2016 Case reports in dermatology

197. Childhood Hypopigmented Mycosis Fungoides: A Rare Diagnosis (PubMed)

Childhood Hypopigmented Mycosis Fungoides: A Rare Diagnosis Primary cutaneous lymphomas (PCL) are rare in pediatrics. Mycosis fungoides (MF) is the most frequent PCL diagnosed in childhood. There are various clinical variants of MF, including the hypopigmented MF (HMF). We present a 5-year-old boy with an 18-month history of progressive, generalized, nonpruritic hypopigmented lesions with central lacy erythema. He had no improvement with emollients. Skin biopsy showed typical features of HMF

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2016 Case reports in pediatrics

198. Mycosis fungoides mimicking tinea pedis (PubMed)

Mycosis fungoides mimicking tinea pedis 27799613 2017 04 03 2018 11 13 1488-2329 188 17-18 2016 Dec 06 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Mycosis fungoides mimicking tinea pedis. E539 Hanna Steven A SA School of Medicine (Hanna), Faculty of Health Sciences; Division of Dermatology, Department of Medicine (Kirchhof), Queen's University, Kingston, Ont. Kirchhof Mark G MG School of Medicine (Hanna), Faculty of Health Sciences; Division (...) of Dermatology, Department of Medicine (Kirchhof), Queen's University, Kingston, Ont. kirchhof.mark@gmail.com. eng Case Reports Journal Article 2016 10 31 Canada CMAJ 9711805 0820-3946 AIM IM Aged Diagnosis, Differential Diagnostic Errors Humans Male Mycosis Fungoides diagnosis Skin Neoplasms diagnosis Tinea Pedis diagnosis 2016 11 2 6 0 2017 4 4 6 0 2016 11 2 6 0 ppublish 27799613 cmaj.160038 10.1503/cmaj.160038 PMC5135541 Mycopathologia. 2008 Nov-Dec;166(5-6):353-67 18478357 J Am Acad Dermatol. 2014 Feb;70

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2016 CMAJ : Canadian Medical Association Journal

199. Mycosis Fungoides of the Oral Cavity: Fungating Tumor Successfully Treated with Electron Beam Radiation and Maintenance Bexarotene (PubMed)

Mycosis Fungoides of the Oral Cavity: Fungating Tumor Successfully Treated with Electron Beam Radiation and Maintenance Bexarotene Oral involvement in mycosis fungoides is unusual and portends a poor prognosis. The clinical findings of three new cases are described along with a differential diagnosis and review of the literature. For brevity, only one patient is discussed in detail below whereas the other two cases are solely described in table form. The patient had a four-year history (...) of mycosis fungoides before developing an exophytic tongue tumor. He was treated with local electron beam radiation and is disease-free to date while being on maintenance therapy with oral bexarotene. Analysis of the data collected from our review of the literature and the present cases reveal key insights.

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2016 Case reports in dermatological medicine

200. Interleukin-12 immunohistochemistry as a diagnostic tool for patch-stage mycosis fungoides (PubMed)

Interleukin-12 immunohistochemistry as a diagnostic tool for patch-stage mycosis fungoides 27745630 2017 04 28 2018 11 13 1097-6787 75 5 2016 Nov Journal of the American Academy of Dermatology J. Am. Acad. Dermatol. Interleukin-12 immunohistochemistry as a diagnostic tool for patch-stage mycosis fungoides. 1053-1054 S0190-9622(16)30397-8 10.1016/j.jaad.2016.06.019 Lemchak David M DM Lake Erie College of Osteopathic Medicine, Erie. Akilov Oleg E OE Department of Dermatology, University (...) of Pittsburgh, Pennsylvania. Electronic address: akilovoe@upmc.edu. eng P50 CA121973 CA NCI NIH HHS United States Journal Article United States J Am Acad Dermatol 7907132 0190-9622 0 Biomarkers, Tumor 0 Interleukin-12 Subunit p35 IM Biomarkers, Tumor analysis Dendritic Cells chemistry Dermis pathology Eczema pathology Female Humans Infant Interleukin-12 Subunit p35 analysis Langerhans Cells chemistry Male Middle Aged Mycosis Fungoides chemistry diagnosis pathology Psoriasis pathology Skin Neoplasms

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2016 Journal of the American Academy of Dermatology

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