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Mycobacterium Avium Complex

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161. Serological Examination of Some Strains That Are in the Mycobacterium avium-intracellulare-scrofulaceum Complex But Do Not Belong to Schaefer's Serotypes Full Text available with Trip Pro

Serological Examination of Some Strains That Are in the Mycobacterium avium-intracellulare-scrofulaceum Complex But Do Not Belong to Schaefer's Serotypes One hundred strains belonging to the Mycobacterium avium-intracellulare-scrofulaceum (MAIS) complex but not agglutinating with antisera type-specific for Schaefer's 23 MAIS serotypes were examined using antisera against seven other such strains. Four of the 100 strains were found to be of the same serotype as one of the 7 against which

1973 Applied microbiology

162. Accurate differentiation of Mycobacterium chimaera from Mycobacterium intracellulare by MALDI-TOF MS analysis. Full Text available with Trip Pro

chimaera and M. intracellulare could not be separated from each other by MALDI-TOF MS.The conventional identification methods used in routine diagnostics have similar limitations. Recently, the differentiation of these two species within the Mycobacterium avium complex has become increasingly important due to reports of M. chimaera infections related to open heart surgery in Europe and in the USA. In this report, a method for the distinct differentiation of M. chimaera and M. intracellulare using (...) Accurate differentiation of Mycobacterium chimaera from Mycobacterium intracellulare by MALDI-TOF MS analysis. The increasing number of infections caused by nontuberculous mycobacteria (NTM) has prompted the need for rapid and precise identification methods of these pathogens. Several studies report the applicability of MALDI-TOF mass spectrometry (MS) for identification of NTM. However, some closely related species have very similar spectral mass fingerprints, and until recently, Mycobacterium

2017 Journal of Medical Microbiology

163. PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. Full Text available with Trip Pro

GENBANK JQ081272 Case Reports Letter 2012 08 30 England J Med Microbiol 0224131 0022-2615 IM AIDS-Related Opportunistic Infections diagnosis Adult Coinfection Fatal Outcome Humans Male Meningitis, Bacterial complications diagnosis Middle Aged Molecular Sequence Data Multiplex Polymerase Chain Reaction Mycobacterium avium Complex genetics isolation & purification Mycobacterium avium-intracellulare Infection complications diagnosis Mycobacterium tuberculosis genetics isolation & purification (...) PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. 22935849 2013 01 18 2012 11 19 1473-5644 61 Pt 12 2012 Dec Journal of medical microbiology J. Med. Microbiol. PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. 1789-91 10.1099/jmm.0.045898-0 Sharma Kusum K Sharma Aman A Modi Manish M Singh Gagandeep G Kaur Harsimran H Varma Subhash S Sharma Meera M eng

2012 Journal of Medical Microbiology

164. Mycobacterium Avium-Intracellulare Infection (Diagnosis)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

165. Mycobacterium Avium-Intracellulare (Diagnosis)

Mycobacterium Avium-Intracellulare (Diagnosis) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

166. Mycobacterium Avium-Intracellulare Infection (Follow-up)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

167. Mycobacterium Avium-Intracellulare (Follow-up)

Mycobacterium Avium-Intracellulare (Follow-up) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

168. Mycobacterium Avium-Intracellulare (Overview)

Mycobacterium Avium-Intracellulare (Overview) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

169. Mycobacterium Avium-Intracellulare Infection (Overview)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

170. Mycobacterium Avium-Intracellulare Infection (Treatment)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

171. Mycobacterium Avium-Intracellulare (Treatment)

Mycobacterium Avium-Intracellulare (Treatment) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

172. Pathogenicity of Mycolicibacterium phlei, a non-pathogenic nontuberculous mycobacterium in an immunocompetent host carrying anti-interferon gamma autoantibodies: a case report. Full Text available with Trip Pro

Pathogenicity of Mycolicibacterium phlei, a non-pathogenic nontuberculous mycobacterium in an immunocompetent host carrying anti-interferon gamma autoantibodies: a case report. Mycolicibacterium phlei (M. phlei) is known to be a non-pathogenic nontuberculous mycobacterium (NTM) which rarely causes diseases in humans. A disseminated NTM infection is mostly caused by the Mycobacterium avium complex (MAC) and is known to develop in immunocompromised hosts, like those with acquired immune

2019 BMC Infectious Diseases

173. Antimicrobial Susceptibility of Clinical and Environmental <i>Mycobacterium chimaera</i> isolates. Full Text available with Trip Pro

Antimicrobial Susceptibility of Clinical and Environmental Mycobacterium chimaera isolates. Mycobacterium chimaera is a slow-growing nontuberculous Mycobacterium species belonging to the Mycobacterium avium Complex (MAC). It has been identified globally as the cause of a large outbreak of cardiovascular infections following open heart surgery, but can also cause respiratory infections in individuals with underlying structural pulmonary disease. Invasive M. chimaera infections

2019 Antimicrobial Agents and Chemotherapy

174. Altered Toll-Like Receptor 9 Signaling in Mycobacterium avium subsp. paratuberculosis-Infected Bovine Monocytes Reveals Potential Therapeutic Targets Full Text available with Trip Pro

Altered Toll-Like Receptor 9 Signaling in Mycobacterium avium subsp. paratuberculosis-Infected Bovine Monocytes Reveals Potential Therapeutic Targets Mycobacterium avium subsp. paratuberculosis is the causative agent of Johne's disease in cattle. The complex, multifaceted interaction of M. avium subsp. paratuberculosis with its host includes dampening the ability of infected cells to respond to stimuli that promote M. avium subsp. paratuberculosis clearance. By disrupting host defenses, M (...) . avium subsp. paratuberculosis creates an intracellular environment that favors the establishment and maintenance of infection. Toll-like receptors (TLRs) are important sensors that initiate innate immune responses to microbial challenge and are also immunotherapeutic targets. For example, TLR9 contributes to host defense against M. avium subsp. paratuberculosis, and its agonists (CpG oligodeoxynucleotides [ODNs]) are under investigation for treatment of Johne's disease and other infections. Here we

2013 Infection and immunity

175. Fast update of undetected Mycobacterium chimaera infections to reveal unsuspected cases. (Abstract)

retrospective Mycobacterium avium-Mycobacterium intracellulare complex isolates, which corresponded to a patient who had undergone heart valve replacement in a different institution. Whole-genome sequencing demonstrated that he was the first case in Spain with involvement of the strain responsible for the global outbreak. These results highlight the relevance of retrospective tracking for undetected M. chimaera infections.Copyright © 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All (...) Fast update of undetected Mycobacterium chimaera infections to reveal unsuspected cases. Mycobacterium chimaera is involved in a worldwide alert due to contaminated heater-cooler units. A real-time polymerase chain reaction (RT-PCR)-based procedure was implemented to survey undetected cases of M. chimaera infection. PCR was negative in the 59 prosthetic heart valves from patients with PCR-16SrRNA-negative infective endocarditis. PCR identified M. chimaera in one of 15 clinically significant

2018 Journal of Hospital Infection

176. Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa Full Text available with Trip Pro

, Mycobacterium fortuitum, a member of the Mycobacterium avium complex, and Mycobacterium szulgai. Phylogenetic analysis of mycobacteria, based on esxA and esxB genes, separated slow growing from rapidly growing mycobacteria as well as pathogenic from non-pathogenic mycobacteria in some cases.Isolation of the different NTM species from samples presenting granuloma suggests the significance of these NTM species in causing mycobacteriosis in these aquatic animals. The study also revealed the potential of esxA (...) Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa Mycobacteriosis caused by non-tuberculous mycobacteria (NTM), is among the most chronic diseases of aquatic animals. In addition, fish mycobacteriosis has substantial economic consequences especially in the aquaculture and fisheries industry as infections may significantly decrease production and trade. Some fish NTM pathogens are highly virulent and zoonotic; as such, infection of aquaria

2018 BMC microbiology

177. Evaluation of the Vitek MS v3.0 Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry System for Identification of Mycobacterium and Nocardia Species Full Text available with Trip Pro

. abscessus, and M. avium complexes and within the M. fortuitum and M. mucogenicum groups could be differentiated. Among the 312 Nocardia isolates tested, 236 (76%) were correctly identified to the species level, with an additional 44 (14%) correctly identified to the complex level. Species within the N. nova and N. transvalensis complexes could not always be differentiated. Eleven percent of the isolates (103/963) underwent repeat testing in order to get a final result. Identification of a representative (...) Evaluation of the Vitek MS v3.0 Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry System for Identification of Mycobacterium and Nocardia Species This multicenter study was designed to assess the accuracy and reproducibility of the Vitek MS v3.0 matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry system for identification of Mycobacterium and Nocardia species compared to DNA sequencing. A total of 963 clinical isolates

2018 Journal of clinical microbiology

178. Characterization of non-tuberculous mycobacterium from humans and water in an Agropastoral area in Zambia. Full Text available with Trip Pro

Characterization of non-tuberculous mycobacterium from humans and water in an Agropastoral area in Zambia. The non-tuberculous mycobacteria include those mycobacterium species that are not members of the Mycobacterium tuberculosis complex, the causative agent of pulmonary tuberculosis and Mycobacterium leprae. In Zambia, Non-tuberculous Mycobacteria are gaining recognition as pathogens of public health significance. However, there is scanty information on the isolation and speciation (...) water, Borehole water, rivers, wells and streams. Standard TB culture methods were employed to isolate Non-tuberculous Mycobacteria and later 16S-23S internal transcribed spacer region Sequencing was employed to characterize NTM.Seven (7, 4.6%) NTM species were identified from humans with M. arupense (3, 42.9%) being the most common organism, while twenty three (23, 15.4%) NTM were identified from water with the common species being Mycobacterium gordonae (5, 21.7%). Mycobacterium avium

2018 BMC Infectious Diseases

179. Mycobacterium triplex Pulmonary Disease with Acquired Macrolide Resistance in Immunocompetent Patients. Full Text available with Trip Pro

Anti-Bacterial Agents 0 Macrolides 0 RNA, Ribosomal, 16S IM Anti-Bacterial Agents adverse effects pharmacology therapeutic use Drug Resistance, Multiple, Bacterial Female Humans Immunocompetence Lung diagnostic imaging microbiology Lung Diseases drug therapy Macrolides adverse effects therapeutic use Middle Aged Mycobacterium Infections, Nontuberculous diagnosis drug therapy Mycobacterium avium Complex drug effects Nontuberculous Mycobacteria drug effects genetics isolation & purification RNA (...) Mycobacterium triplex Pulmonary Disease with Acquired Macrolide Resistance in Immunocompetent Patients. 29309938 2018 11 08 2018 11 08 1469-0691 24 6 2018 Jun Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases Clin. Microbiol. Infect. Mycobacterium triplex pulmonary disease with acquired macrolide resistance in immunocompetent patients. 671-672 S1198-743X(17)30713-9 10.1016/j.cmi.2017.12.018 Matsuda S S

2018 Clinical Microbiology and Infection

180. Endobronchial Non-Tuberculosis Mycobacterium Infection Presenting in a Healthy Child. (Abstract)

Endobronchial Non-Tuberculosis Mycobacterium Infection Presenting in a Healthy Child. To describe a safe and effective treatment for endobronchial Mycobacterium avium complex.Case report and literature review.We present a case of endobronchial M. avium complex in a healthy child treated with serial carbon-dioxide laser excisions and antibiotic triple therapy using azithromycin, rifampin, and ethambutol. No current guideline for the treatment of these lesions in the pediatric population

2018 Rhinology and Laryngology

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