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1,178 results for

Mycobacterium Avium Complex

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161. Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. Full Text available with Trip Pro

Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. Mycobacterium avium complex lung disease is an increasingly common and chronically debilitating problem. Several host traits have been suggested or confirmed as risk factors. Potential environmental and behavioral risk factors have also been proposed. Few have been evaluated in comparative studies.To determine if aerosol-generating activities in the home and garden, features of the home (...) water supply, or several pulmonary and immune-compromising conditions are associated with Mycobacterium avium complex lung disease.Cases were recruited from academic medical centers and by informal referrals from nonuniversity practices in Washington and Oregon. Control subjects were recruited by random-digit dialing and matched to cases by age, sex, and partial telephone number. Associations were measured as odds ratios (OR) estimated using conditional logistic regression.Known and potential risk

2012 American Journal of Respiratory and Critical Care Medicine

162. Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. Full Text available with Trip Pro

Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. Although opportunistic infections due to Mycobacterium avium complex (MAC) have been less common since the introduction of highly active antiretroviral therapy, globally, human immunodeficiency virus-1 (HIV-1)-positive patients remain predisposed to these infections. Absence of a properly functioning acquired immune response allows MAC persistence within macrophages localized in lymph

2012 Journal of Infectious Diseases

163. Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. Full Text available with Trip Pro

Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. Mycobacterium avium-intracellulare complex (MAC) strains were recovered from 48.9% of residential soil samples (agricultural farms (n = 7), residential yards (n = 79), and planting pots (n = 49)) of 100 pulmonary MAC patients and 35 non-infected control patients. The frequency of MAC recovery did not differ among soil types or among patients regardless (...) of the presence of pulmonary MAC disease, infecting MAC species or period of soil exposure. Variable numbers of tandem repeats (VNTR) analysis for MAC clinical and soil isolates revealed 78 different patterns in 47 M. avium clinical isolates and 41 soil isolates, and 53 different patterns in 18 M. intracellulare clinical isolates and 37 soil isolates. Six clinical and corresponding soil isolate pairs with an identical VNTR genotype were from case patients with high soil exposure (≥2 h per week, 37.5% (6/16

2012 Clinical Microbiology and Infection

164. Clinical Evaluation of COBAS TaqMan PCR for the Detection of Mycobacterium tuberculosis and M. avium Complex Full Text available with Trip Pro

Clinical Evaluation of COBAS TaqMan PCR for the Detection of Mycobacterium tuberculosis and M. avium Complex A retrospective observational study was performed to determine the sensitivity and limitation of PCR test for the detection of Mycobacterium tuberculosis and M. avium complex. We obtained clinical specimens collected from the respiratory tract, cultured M. tuberculosis or M. avium complex, and performed PCR analysis. A total of 299 samples (M. tuberculosis, 177; M. avium, 35; M (...) . intracellulare, 87) were analyzed by COBAS TaqMan PCR from April 2007 to March 2011. The PCR positivity rates were 50-55%, 70-100%, 88-98%, and 100% in smear-negative, smear 1+, 2+, and 3+ groups, respectively. The PCR positivity of tuberculosis in smear 1+ was 80.6%, which was statistically significantly (P < 0.001) lower than that of smear 2+ (97.3%). From January 2005 to March 2007, we collected an additional 138 samples (M. tuberculosis, 74; M. avium, 21; M. intracellulare, 43), which were analyzed

2012 Tuberculosis research and treatment

165. Association between pulmonary mycobacterium avium complex infection and lung cancer. Full Text available with Trip Pro

Association between pulmonary mycobacterium avium complex infection and lung cancer. Patients with lung cancer are sometimes found to have respiratory cultures growing Mycobacterium avium complex (MAC). This study describes the clinical, pathologic, and radiographic -characteristics of individuals who harbor concomitant lung cancer and MAC.Retrospective analysis of patients with positive respiratory cultures for MAC (370 men, 475 women) and with newly diagnosed lung cancer (792 men, 840 women

2012 Journal of Thoracic Oncology

166. Modification of Schaefer's Procedure for Serotyping of Organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex Full Text available with Trip Pro

Modification of Schaefer's Procedure for Serotyping of Organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex Modifications to the tube-agglutination procedure which Schaefer developed for serotyping of organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex are proposed.

1972 Applied microbiology

167. Serological Examination of Some Strains That Are in the Mycobacterium avium-intracellulare-scrofulaceum Complex But Do Not Belong to Schaefer's Serotypes Full Text available with Trip Pro

Serological Examination of Some Strains That Are in the Mycobacterium avium-intracellulare-scrofulaceum Complex But Do Not Belong to Schaefer's Serotypes One hundred strains belonging to the Mycobacterium avium-intracellulare-scrofulaceum (MAIS) complex but not agglutinating with antisera type-specific for Schaefer's 23 MAIS serotypes were examined using antisera against seven other such strains. Four of the 100 strains were found to be of the same serotype as one of the 7 against which

1973 Applied microbiology

168. Primary isolation of Mycobacterium avium complex-serotype 6 on blood agar. Full Text available with Trip Pro

Primary isolation of Mycobacterium avium complex-serotype 6 on blood agar. Mycobacterium avium complex-serotype 6 was isolated in pure culture on blood agar plates from inocula taken from the heart blood, lungs, liver, kidneys, and spleen of a naturally infected captive female opossum (Didelphis marsupialis virginiana). Repeat cultures from stored tissues and transfer of colonies from original blood agar plates revealed that the mycobacterium grew on tryptose, brilliant green, eosin-methylene (...) blue. Sabouraud glucose, and mycobiotic agar plates and in Fletcher leptospira medium. The cultural, biochemical, and serological characteristics of the test isolate were compared with other mycobacteria. This is the first report to describe the primary isolation of a serotype from the M. avium complex from an animal species on blood agar or in Fletcher broth. In addition, this is the second documented report describing the isolation and identification of a mycobacterial species from the American

1976 Journal of clinical microbiology

169. Comparison of four culture media for isolation of Mycobacterium avium complex from porcine tissues. Full Text available with Trip Pro

Comparison of four culture media for isolation of Mycobacterium avium complex from porcine tissues. The efficiency of four culture media was compared for the isolation of Mycobacterium avium complex from 197 procine tissues. In 82 tissues with microscopic granulomas and acid-fast bacilli, a significantly greater number of isolates were obtained on Middlebrook 7H10 medium with sodium pyruvate than on Stonebrink medium, Herrold egg yolk agar medium, or Lowenstein-Jensen medium (P=0.01). In 46 (...) tissues in which no microscopic granulomas or acid-fast bacilli were observed, a significantly greater number of isolates were made on Middlebrook 7H10 medium or Herrold egg yolk agar medium than on Stonebrink medium or on Lowenstein-Jensen medium (P=0.01). The time required to grow M. avium complex on Lowenstein-Jensen medium was significantly greater than the time required to observe growth on Stonebrink, Middlebrook 7H10, or Herrold egg yolk agar medium (p=0.001).

1979 Journal of clinical microbiology

170. Long-term follow-up of post-cardiac surgery Mycobacterium chimaera infections: A 5-center case series. (Abstract)

for survivors.Identified at five hospitals in the United States 2010-2016, post-cardiac surgery patients in the cohort had growth of Mycobacterium avium complex (MAC)/M. chimaera from a sterile site or surgical wound, or a clinically compatible febrile illness with granulomatous inflammation on biopsy. Case follow-up was conducted in May 2019.Of 28 patients, infection appeared to be localized to the sternum in four patients. Among 18 with endovascular/disseminated infection who received combination anti-mycobacterial (...) Long-term follow-up of post-cardiac surgery Mycobacterium chimaera infections: A 5-center case series. In multiple countries, endovascular/disseminated Mycobacterium chimaera infections have occurred in post-cardiac surgery patients in association with contaminated, widely-distributed cardiac bypass heater-cooler devices. To contribute to long-term characterization of this recently recognized infection, we describe the clinical course of 28 patients with 3-7 years of follow-up

2020 Journal of Infection

171. Clinical features and treatment outcomes of Mycobacterium chimaera lung disease and antimicrobial susceptibility of the mycobacterial isolates. (Abstract)

Clinical features and treatment outcomes of Mycobacterium chimaera lung disease and antimicrobial susceptibility of the mycobacterial isolates. Mycobacterium chimaera, one of the Mycobacterium avium complex (MAC) members, was recently identified using modern gene sequencing analysis. Unlike M. avium and M. intracellulare, little is known about the clinical features, antimicrobial susceptibilities, and treatment outcomes of M. chimaera lung disease.This study was conducted in a medical center

2020 Journal of Infection

172. Accurate differentiation of Mycobacterium chimaera from Mycobacterium intracellulare by MALDI-TOF MS analysis. Full Text available with Trip Pro

chimaera and M. intracellulare could not be separated from each other by MALDI-TOF MS.The conventional identification methods used in routine diagnostics have similar limitations. Recently, the differentiation of these two species within the Mycobacterium avium complex has become increasingly important due to reports of M. chimaera infections related to open heart surgery in Europe and in the USA. In this report, a method for the distinct differentiation of M. chimaera and M. intracellulare using (...) Accurate differentiation of Mycobacterium chimaera from Mycobacterium intracellulare by MALDI-TOF MS analysis. The increasing number of infections caused by nontuberculous mycobacteria (NTM) has prompted the need for rapid and precise identification methods of these pathogens. Several studies report the applicability of MALDI-TOF mass spectrometry (MS) for identification of NTM. However, some closely related species have very similar spectral mass fingerprints, and until recently, Mycobacterium

2017 Journal of Medical Microbiology

173. PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. Full Text available with Trip Pro

GENBANK JQ081272 Case Reports Letter 2012 08 30 England J Med Microbiol 0224131 0022-2615 IM AIDS-Related Opportunistic Infections diagnosis Adult Coinfection Fatal Outcome Humans Male Meningitis, Bacterial complications diagnosis Middle Aged Molecular Sequence Data Multiplex Polymerase Chain Reaction Mycobacterium avium Complex genetics isolation & purification Mycobacterium avium-intracellulare Infection complications diagnosis Mycobacterium tuberculosis genetics isolation & purification (...) PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. 22935849 2013 01 18 2012 11 19 1473-5644 61 Pt 12 2012 Dec Journal of medical microbiology J. Med. Microbiol. PCR detection of co-infection with Mycobacterium tuberculosis and Mycobacterium avium in AIDS patients with meningitis. 1789-91 10.1099/jmm.0.045898-0 Sharma Kusum K Sharma Aman A Modi Manish M Singh Gagandeep G Kaur Harsimran H Varma Subhash S Sharma Meera M eng

2012 Journal of Medical Microbiology

174. Mycobacterium Avium-Intracellulare (Diagnosis)

Mycobacterium Avium-Intracellulare (Diagnosis) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

175. Mycobacterium Avium-Intracellulare Infection (Diagnosis)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

176. Mycobacterium Avium-Intracellulare (Treatment)

Mycobacterium Avium-Intracellulare (Treatment) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

177. Mycobacterium Avium-Intracellulare Infection (Treatment)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

178. Mycobacterium Avium-Intracellulare (Overview)

Mycobacterium Avium-Intracellulare (Overview) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

179. Mycobacterium Avium-Intracellulare Infection (Overview)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

180. Mycobacterium Avium-Intracellulare (Follow-up)

Mycobacterium Avium-Intracellulare (Follow-up) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

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