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1,145 results for

Mycobacterium Avium Complex

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141. Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in aqueous suspension. (PubMed)

Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in aqueous suspension. Isolants from swine and from humans representing serotypes 1, 2, 4, 8, and 10 of the Mycobacterium avium-Mycobacterium intracellulare complex were compared for heat tolerance in aqueous suspension. The most heat-resistant isolant found was a serovar 10 isolated from a human. This isolant was examined further to determine the rate of kill at various temperatures and pH's, the effect

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1979 Applied and environmental microbiology

142. Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in meat products. (PubMed)

Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in meat products. Wieners and sausages were prepared which contained the most heat-tolerant representative of the Mycobacterium avium-Mycobacterium intracellulare complex we were able to obtain. They also were prepared with infected tissues obtained from tuberculous swine. Processing conditions were as varied as possible. Neither incorporation of sodium nitrite in the emulsion nor presence of smoke during

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1979 Applied and environmental microbiology

143. Production of Multivalent Fluorescent Antisera for Identification of Organisms in the Mycobacterium avium-Mycobacterium intracellulare Complex (PubMed)

Production of Multivalent Fluorescent Antisera for Identification of Organisms in the Mycobacterium avium-Mycobacterium intracellulare Complex Antisera to ten strains of mycobacteria in the Mycobacterium avium-Mycobacterium intracellulare group were obtained by injecting rabbits with ultraviolet light-killed cells. The antisera were conjugated with fluorescein isothiocyanate and used in the direct fluorescent antibody test. Individual antisera reacted specifically with the mycobacterial

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1974 Applied microbiology

144. Bovine Immunoinhibitory Receptors Contribute to Suppression of Mycobacterium avium subsp. paratuberculosis-Specific T-Cell Responses (PubMed)

Bovine Immunoinhibitory Receptors Contribute to Suppression of Mycobacterium avium subsp. paratuberculosis-Specific T-Cell Responses Johne's disease (paratuberculosis) is a chronic enteritis in cattle that is caused by intracellular infection with Mycobacterium avium subsp. paratuberculosis. This infection is characterized by the functional exhaustion of T-cell responses to M. avium subsp. paratuberculosis antigens during late subclinical and clinical stages, presumably facilitating (...) the persistence of this bacterium and the formation of clinical lesions. However, the mechanisms underlying T-cell exhaustion in Johne's disease are poorly understood. Thus, we performed expression and functional analyses of the immunoinhibitory molecules programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) and lymphocyte activation gene 3 (LAG-3)/major histocompatibility complex class II (MHC-II) in M. avium subsp. paratuberculosis-infected cattle during the late subclinical stage. Flow cytometric analyses revealed

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2015 Infection and immunity

145. In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis (PubMed)

In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis Mycobacterium avium ssp. paratuberculosis (MAP) is the causative agent of a chronic enteric disease of ruminants. Available diagnostic tests are complex and slow. In vitro, volatile organic compound (VOC) patterns emitted from MAP cultures mirrored bacterial growth and enabled distinction of different strains. This study was intended to determine VOCs in vivo in the controlled setting of an animal model

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2015 PloS one

146. Detection of Mycobacterium avium subspecies in the gut associated lymphoid tissue of slaughtered rabbits (PubMed)

Detection of Mycobacterium avium subspecies in the gut associated lymphoid tissue of slaughtered rabbits Rabbits are susceptible to infection by different species of the genus Mycobacterium. Particularly, development of specific lesions and isolation of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis, both subspecies of the M. avium complex, has been reported in wildlife conditions. Although, rabbit meat production worldwide is 200 million tons per year (...) , microbiological data on this source of meat is lacking and more specifically reports of mycobacterial presence in industrially reared rabbit for human consumption have not been published. To this end, we sought mycobacteria by microbiological and histopathological methods paying special attention to Mycobacterium avium subsp. paratuberculosis in rabbits from commercial rabbitries from the North East of Spain.M. avium subsp. paratuberculosis was not detected either by culture or PCR. However, Mycobacterium

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2015 BMC veterinary research

147. Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. (PubMed)

Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. Although opportunistic infections due to Mycobacterium avium complex (MAC) have been less common since the introduction of highly active antiretroviral therapy, globally, human immunodeficiency virus-1 (HIV-1)-positive patients remain predisposed to these infections. Absence of a properly functioning acquired immune response allows MAC persistence within macrophages localized in lymph

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2012 Journal of Infectious Diseases

148. Serodiagnosis of Mycobacterium avium complex pulmonary disease in the United States. (PubMed)

Serodiagnosis of Mycobacterium avium complex pulmonary disease in the United States. Diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) can be difficult. A previous study from Japan reported the usefulness of a serodiagnostic test for MAC-PD. The objective of this study was to evaluate the usefulness of the test in similar patients in the USA. 100 patients with known or suspected MAC-PD and 52 healthy volunteers were enrolled into the study at National Jewish Health, Denver, CO

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2012 European Respiratory Journal

149. Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. (PubMed)

Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. Mycobacterium avium-intracellulare complex (MAC) strains were recovered from 48.9% of residential soil samples (agricultural farms (n = 7), residential yards (n = 79), and planting pots (n = 49)) of 100 pulmonary MAC patients and 35 non-infected control patients. The frequency of MAC recovery did not differ among soil types or among patients regardless (...) of the presence of pulmonary MAC disease, infecting MAC species or period of soil exposure. Variable numbers of tandem repeats (VNTR) analysis for MAC clinical and soil isolates revealed 78 different patterns in 47 M. avium clinical isolates and 41 soil isolates, and 53 different patterns in 18 M. intracellulare clinical isolates and 37 soil isolates. Six clinical and corresponding soil isolate pairs with an identical VNTR genotype were from case patients with high soil exposure (≥2 h per week, 37.5% (6/16

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2012 Clinical Microbiology and Infection

150. Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. (PubMed)

Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. Mycobacterium avium complex lung disease is an increasingly common and chronically debilitating problem. Several host traits have been suggested or confirmed as risk factors. Potential environmental and behavioral risk factors have also been proposed. Few have been evaluated in comparative studies.To determine if aerosol-generating activities in the home and garden, features of the home (...) water supply, or several pulmonary and immune-compromising conditions are associated with Mycobacterium avium complex lung disease.Cases were recruited from academic medical centers and by informal referrals from nonuniversity practices in Washington and Oregon. Control subjects were recruited by random-digit dialing and matched to cases by age, sex, and partial telephone number. Associations were measured as odds ratios (OR) estimated using conditional logistic regression.Known and potential risk

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2012 American Journal of Respiratory and Critical Care Medicine

151. A Case of Congenital Cystic Adenomatoid Malformation Infected with Mycobacterium avium-intracellulare Complex (PubMed)

A Case of Congenital Cystic Adenomatoid Malformation Infected with Mycobacterium avium-intracellulare Complex We present a case of congenital cystic adenomatoid malformation (CCAM) in a 25-year-old male who was presented with chronic cough. Chest radiography revealed an abnormal mass-like shadow in the right lower pulmonary zone. A contrast enhanced computed tomography showed an 11 cm solid, cystic mixed mass on the right lower lobe. A right lower lobectomy was performed by video-assisted (...) thoracoscopic surgery without complications. The gross specimen showed a massive cavitation with multiloculated cysts of varying size, consistent with CCAM, along with noticeable granulomatous inflammation. Non-tuberculosis mycobacteria were isolated from a bronchial wash specimen, and the resected tissue homogenates were positive for Mycobacterium avium-intracellulare complex by polymerase chain reaction.

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2013 Tuberculosis and respiratory diseases

152. Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins (PubMed)

Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins The Esx and PE/PPE families of proteins are among the most immunodominant mycobacterial antigens and have thus been the focus of research to develop vaccines and immunological tests for diagnosis of bovine and human tuberculosis, mainly caused by Mycobacterium bovis and Mycobacterium tuberculosis, respectively. In non (...) available purified protein derivatives from Mycobacterium bovis and Mycobacterium avium was performed. The genomic analysis revealed the occurrence in each of the four NTM, orthologs of the genes encoding for the Esx family, the PE and PPE family proteins in M. bovis and M. tuberculosis. The identification of genes of the ESX-1, ESX-3, and ESX-4 region including esxA, esxB, ppe68, pe5, and pe35 adds to earlier reports of these genes in nonpathogenic NTM like M. smegmatis, Mycobacterium sp. JLS

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2016 Frontiers in microbiology

153. Mycobacterium Avium-Intracellulare (Diagnosis)

Mycobacterium Avium-Intracellulare (Diagnosis) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

154. Mycobacterium Avium-Intracellulare Infection (Diagnosis)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

155. Mycobacterium Avium-Intracellulare Infection (Overview)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

156. Mycobacterium Avium-Intracellulare (Overview)

Mycobacterium Avium-Intracellulare (Overview) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]): Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LW92ZXJ2aWV3 processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Overview Background Mycobacterium avium complex (MAC) consists of two species: M avium and M intracellulare ; because these species are difficult to differentiate

2014 eMedicine.com

157. Mycobacterium Avium-Intracellulare (Treatment)

Mycobacterium Avium-Intracellulare (Treatment) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

158. Mycobacterium Avium-Intracellulare Infection (Treatment)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

159. Mycobacterium Avium-Intracellulare Infection (Follow-up)

preexisting lung disease. Sputum culture grew Mycobacterium avium complex. The diagnosis was Lady Windermere syndrome. An interesting case reported in 2012 involved in a child with complete interferon (IFN)–γ receptor-1 deficiency interrupting the interleukin (IL)–12/IFN-γ pathway and resulting in granulomatous skin papules and plaques and lower extremity edema. In this child, recurrent infection with MAI, Mycobacterium tuberculosis , Mycobacterium bovis , and Mycobacterium fortuitum all occurred. [ ] MAI (...) complex involving osteomyelitis, DRESS syndrome has been reported to occur. [ ] MAI olecranon bursitis resolving without surgical or antimicrobial intervention has been noted to occur. [ ] Previous Next: Workup Considerations Primary cutaneous Mycobacterium avium-intracellulare (MAI, or MAC) infection is rare, but it does not necessarily mandate a workup for immunosuppression. Biopsy should be performed for suspected dermatologic manifestations of MAI infection. Tissue samples of cutaneous lesions may

2014 eMedicine.com

160. Mycobacterium Avium-Intracellulare (Follow-up)

Mycobacterium Avium-Intracellulare (Follow-up) Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management: Approach Considerations, Pulmonary MAC Infection in Immunocompetent Patients, Disseminated MAC Infection in Patients with AIDS Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px (...) /getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjIyNjY0LXRyZWF0bWVudA== processing > Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment & Management Updated: Oct 18, 2018 Author: Janak Koirala, MD, MPH, FACP, FIDSA; Chief Editor: Michael Stuart Bronze, MD Share Email Print Feedback Close Sections Sections Mycobacterium Avium Complex (MAC) (Mycobacterium Avium-Intracellulare [MAI]) Treatment Approach Considerations

2014 eMedicine.com

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