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Mycobacterium Avium Complex

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141. Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in meat products. Full Text available with Trip Pro

Heat inactivation of Mycobacterium avium-Mycobacterium intracellulare complex organisms in meat products. Wieners and sausages were prepared which contained the most heat-tolerant representative of the Mycobacterium avium-Mycobacterium intracellulare complex we were able to obtain. They also were prepared with infected tissues obtained from tuberculous swine. Processing conditions were as varied as possible. Neither incorporation of sodium nitrite in the emulsion nor presence of smoke during

1979 Applied and environmental microbiology

142. Bovine Immunoinhibitory Receptors Contribute to Suppression of Mycobacterium avium subsp. paratuberculosis-Specific T-Cell Responses Full Text available with Trip Pro

Bovine Immunoinhibitory Receptors Contribute to Suppression of Mycobacterium avium subsp. paratuberculosis-Specific T-Cell Responses Johne's disease (paratuberculosis) is a chronic enteritis in cattle that is caused by intracellular infection with Mycobacterium avium subsp. paratuberculosis. This infection is characterized by the functional exhaustion of T-cell responses to M. avium subsp. paratuberculosis antigens during late subclinical and clinical stages, presumably facilitating (...) the persistence of this bacterium and the formation of clinical lesions. However, the mechanisms underlying T-cell exhaustion in Johne's disease are poorly understood. Thus, we performed expression and functional analyses of the immunoinhibitory molecules programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) and lymphocyte activation gene 3 (LAG-3)/major histocompatibility complex class II (MHC-II) in M. avium subsp. paratuberculosis-infected cattle during the late subclinical stage. Flow cytometric analyses revealed

2015 Infection and immunity

143. Detection of Mycobacterium avium subspecies in the gut associated lymphoid tissue of slaughtered rabbits Full Text available with Trip Pro

Detection of Mycobacterium avium subspecies in the gut associated lymphoid tissue of slaughtered rabbits Rabbits are susceptible to infection by different species of the genus Mycobacterium. Particularly, development of specific lesions and isolation of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis, both subspecies of the M. avium complex, has been reported in wildlife conditions. Although, rabbit meat production worldwide is 200 million tons per year (...) , microbiological data on this source of meat is lacking and more specifically reports of mycobacterial presence in industrially reared rabbit for human consumption have not been published. To this end, we sought mycobacteria by microbiological and histopathological methods paying special attention to Mycobacterium avium subsp. paratuberculosis in rabbits from commercial rabbitries from the North East of Spain.M. avium subsp. paratuberculosis was not detected either by culture or PCR. However, Mycobacterium

2015 BMC veterinary research

144. In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis Full Text available with Trip Pro

In Vivo Volatile Organic Compound Signatures of Mycobacterium avium subsp. paratuberculosis Mycobacterium avium ssp. paratuberculosis (MAP) is the causative agent of a chronic enteric disease of ruminants. Available diagnostic tests are complex and slow. In vitro, volatile organic compound (VOC) patterns emitted from MAP cultures mirrored bacterial growth and enabled distinction of different strains. This study was intended to determine VOCs in vivo in the controlled setting of an animal model

2015 PloS one

145. Diagnostic test accuracy of anti-glycopeptidolipid-core IgA antibody for Mycobacterium avium complex infection: systematic review and meta-analysis

Diagnostic test accuracy of anti-glycopeptidolipid-core IgA antibody for Mycobacterium avium complex infection: systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2016 PROSPERO

146. A Case of Congenital Cystic Adenomatoid Malformation Infected with Mycobacterium avium-intracellulare Complex Full Text available with Trip Pro

A Case of Congenital Cystic Adenomatoid Malformation Infected with Mycobacterium avium-intracellulare Complex We present a case of congenital cystic adenomatoid malformation (CCAM) in a 25-year-old male who was presented with chronic cough. Chest radiography revealed an abnormal mass-like shadow in the right lower pulmonary zone. A contrast enhanced computed tomography showed an 11 cm solid, cystic mixed mass on the right lower lobe. A right lower lobectomy was performed by video-assisted (...) thoracoscopic surgery without complications. The gross specimen showed a massive cavitation with multiloculated cysts of varying size, consistent with CCAM, along with noticeable granulomatous inflammation. Non-tuberculosis mycobacteria were isolated from a bronchial wash specimen, and the resected tissue homogenates were positive for Mycobacterium avium-intracellulare complex by polymerase chain reaction.

2013 Tuberculosis and respiratory diseases

147. Comparison of Mycobacterium lentiflavum and M. avium-intracellulare Complex Lymphadenitis. (Abstract)

Comparison of Mycobacterium lentiflavum and M. avium-intracellulare Complex Lymphadenitis. Mycobacterium lentiflavum is considered a rare pathogen causing nontuberculous mycobacterial (NTM) lymphadenitis.A multicenter, retrospective study was performed in immunocompetent children <14 years of age with microbiologically confirmed NTM lymphadenitis treated at 6 hospitals in Madrid, Spain, during 2000-2010. We compared children with M. lentiflavum and Mycobacterium avium-intracellulare complex (...) infection.Forty-five microbiologically confirmed NTM lymphadenitis patients were identified: 19 (45.2%) caused by M. avium-intracellulare complex, 17 (40.5%) by M. lentiflavum, 1 by both and 5 by other mycobacteria. Out of 17 M. lentiflavum cases, 14 were diagnosed in the past 5 years. Regarding M. lentiflavum cases, median age was 23 months. Submandibular nodes were the most frequently involved (76.5%), with multiple locations seen in 41% of the children and spontaneous drainage in 41% of them. Drug

2013 Pediatric Infectious Dsease Journal

148. Interventions for the prevention of mycobacterium avium complex in adults and children with HIV. (Abstract)

Interventions for the prevention of mycobacterium avium complex in adults and children with HIV. Mycobacterium avium complex (MAC) infection is a common complication of advanced acquired immunodeficiency syndrome (AIDS) disease and is an independent predictor of mortality and shortened survival.To determine the effectiveness and safety of interventions aimed at preventing MAC infection in adults and children with HIV infection.We searched MEDLINE, EMBASE, and The Cochrane Library (search date

2013 Cochrane database of systematic reviews (Online)

149. Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins Full Text available with Trip Pro

Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins The Esx and PE/PPE families of proteins are among the most immunodominant mycobacterial antigens and have thus been the focus of research to develop vaccines and immunological tests for diagnosis of bovine and human tuberculosis, mainly caused by Mycobacterium bovis and Mycobacterium tuberculosis, respectively. In non (...) available purified protein derivatives from Mycobacterium bovis and Mycobacterium avium was performed. The genomic analysis revealed the occurrence in each of the four NTM, orthologs of the genes encoding for the Esx family, the PE and PPE family proteins in M. bovis and M. tuberculosis. The identification of genes of the ESX-1, ESX-3, and ESX-4 region including esxA, esxB, ppe68, pe5, and pe35 adds to earlier reports of these genes in nonpathogenic NTM like M. smegmatis, Mycobacterium sp. JLS

2016 Frontiers in microbiology

150. Significant Difference in Drug Susceptibility Distribution between Mycobacterium avium and Mycobacterium intracellulare Full Text available with Trip Pro

, Center for Immunology and Microbial Infections, Team 13, Paris, France jerome.robert0@upmc.fr. eng Comparative Study Letter Research Support, Non-U.S. Gov't 2014 10 01 United States J Clin Microbiol 7505564 0095-1137 0 Antitubercular Agents 84319SGC3C Amikacin H1250JIK0A Clarithromycin IM Amikacin pharmacology Antitubercular Agents pharmacology Clarithromycin pharmacology Humans Microbial Sensitivity Tests Mycobacterium avium drug effects Mycobacterium avium Complex drug effects 2014 10 3 6 0 2014 10 (...) Significant Difference in Drug Susceptibility Distribution between Mycobacterium avium and Mycobacterium intracellulare 25274991 2015 10 15 2018 11 13 1098-660X 52 12 2014 Dec Journal of clinical microbiology J. Clin. Microbiol. Significant difference in drug susceptibility distribution between Mycobacterium avium and Mycobacterium intracellulare. 4439-40 10.1128/JCM.02127-14 Renvoisé Aurélie A AP-HP, Hôpital Pitié-Salpêtrière, Centre National de Référence des Mycobactéries et de la Résistance

2014 Journal of clinical microbiology

151. Mycobacterium Avium Complex

Mycobacterium Avium Complex Mycobacterium Avium Complex Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Mycobacterium Avium Complex (...) Mycobacterium Avium Complex Aka: Mycobacterium Avium Complex , Mycobacterium Avium Intracellulare From Related Chapters II. Epidemiology Disseminated MAC infection: 40% of North American Most common reported HIV Normal Children may develop Occurs under age 5 years Rarely affects children over age 12 years III. Pathophysiology MAC is ubiquitous in environment (water, soil, food) Causes in birds and swine Colonization by respiratory and gastrointestinal tracts Rarely occurs if >50 Infection in normal children

2015 FP Notebook

152. Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. Full Text available with Trip Pro

Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17. Although opportunistic infections due to Mycobacterium avium complex (MAC) have been less common since the introduction of highly active antiretroviral therapy, globally, human immunodeficiency virus-1 (HIV-1)-positive patients remain predisposed to these infections. Absence of a properly functioning acquired immune response allows MAC persistence within macrophages localized in lymph

2012 Journal of Infectious Diseases

153. Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. Full Text available with Trip Pro

Environment or Host?: A Case-control Study of Risk Factors for Mycobacterium Avium Complex Lung Disease. Mycobacterium avium complex lung disease is an increasingly common and chronically debilitating problem. Several host traits have been suggested or confirmed as risk factors. Potential environmental and behavioral risk factors have also been proposed. Few have been evaluated in comparative studies.To determine if aerosol-generating activities in the home and garden, features of the home (...) water supply, or several pulmonary and immune-compromising conditions are associated with Mycobacterium avium complex lung disease.Cases were recruited from academic medical centers and by informal referrals from nonuniversity practices in Washington and Oregon. Control subjects were recruited by random-digit dialing and matched to cases by age, sex, and partial telephone number. Associations were measured as odds ratios (OR) estimated using conditional logistic regression.Known and potential risk

2012 American Journal of Respiratory and Critical Care Medicine

154. Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. Full Text available with Trip Pro

Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils. Mycobacterium avium-intracellulare complex (MAC) strains were recovered from 48.9% of residential soil samples (agricultural farms (n = 7), residential yards (n = 79), and planting pots (n = 49)) of 100 pulmonary MAC patients and 35 non-infected control patients. The frequency of MAC recovery did not differ among soil types or among patients regardless (...) of the presence of pulmonary MAC disease, infecting MAC species or period of soil exposure. Variable numbers of tandem repeats (VNTR) analysis for MAC clinical and soil isolates revealed 78 different patterns in 47 M. avium clinical isolates and 41 soil isolates, and 53 different patterns in 18 M. intracellulare clinical isolates and 37 soil isolates. Six clinical and corresponding soil isolate pairs with an identical VNTR genotype were from case patients with high soil exposure (≥2 h per week, 37.5% (6/16

2012 Clinical Microbiology and Infection

155. Serodiagnosis of Mycobacterium avium complex pulmonary disease in the United States. Full Text available with Trip Pro

Serodiagnosis of Mycobacterium avium complex pulmonary disease in the United States. Diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) can be difficult. A previous study from Japan reported the usefulness of a serodiagnostic test for MAC-PD. The objective of this study was to evaluate the usefulness of the test in similar patients in the USA. 100 patients with known or suspected MAC-PD and 52 healthy volunteers were enrolled into the study at National Jewish Health, Denver, CO

2012 European Respiratory Journal

156. Association between pulmonary mycobacterium avium complex infection and lung cancer. Full Text available with Trip Pro

Association between pulmonary mycobacterium avium complex infection and lung cancer. Patients with lung cancer are sometimes found to have respiratory cultures growing Mycobacterium avium complex (MAC). This study describes the clinical, pathologic, and radiographic -characteristics of individuals who harbor concomitant lung cancer and MAC.Retrospective analysis of patients with positive respiratory cultures for MAC (370 men, 475 women) and with newly diagnosed lung cancer (792 men, 840 women

2012 Journal of Thoracic Oncology

157. Clinical Evaluation of COBAS TaqMan PCR for the Detection of Mycobacterium tuberculosis and M. avium Complex Full Text available with Trip Pro

Clinical Evaluation of COBAS TaqMan PCR for the Detection of Mycobacterium tuberculosis and M. avium Complex A retrospective observational study was performed to determine the sensitivity and limitation of PCR test for the detection of Mycobacterium tuberculosis and M. avium complex. We obtained clinical specimens collected from the respiratory tract, cultured M. tuberculosis or M. avium complex, and performed PCR analysis. A total of 299 samples (M. tuberculosis, 177; M. avium, 35; M (...) . intracellulare, 87) were analyzed by COBAS TaqMan PCR from April 2007 to March 2011. The PCR positivity rates were 50-55%, 70-100%, 88-98%, and 100% in smear-negative, smear 1+, 2+, and 3+ groups, respectively. The PCR positivity of tuberculosis in smear 1+ was 80.6%, which was statistically significantly (P < 0.001) lower than that of smear 2+ (97.3%). From January 2005 to March 2007, we collected an additional 138 samples (M. tuberculosis, 74; M. avium, 21; M. intracellulare, 43), which were analyzed

2012 Tuberculosis research and treatment

158. Primary isolation of Mycobacterium avium complex-serotype 6 on blood agar. Full Text available with Trip Pro

Primary isolation of Mycobacterium avium complex-serotype 6 on blood agar. Mycobacterium avium complex-serotype 6 was isolated in pure culture on blood agar plates from inocula taken from the heart blood, lungs, liver, kidneys, and spleen of a naturally infected captive female opossum (Didelphis marsupialis virginiana). Repeat cultures from stored tissues and transfer of colonies from original blood agar plates revealed that the mycobacterium grew on tryptose, brilliant green, eosin-methylene (...) blue. Sabouraud glucose, and mycobiotic agar plates and in Fletcher leptospira medium. The cultural, biochemical, and serological characteristics of the test isolate were compared with other mycobacteria. This is the first report to describe the primary isolation of a serotype from the M. avium complex from an animal species on blood agar or in Fletcher broth. In addition, this is the second documented report describing the isolation and identification of a mycobacterial species from the American

1976 Journal of clinical microbiology

159. Modification of Schaefer's Procedure for Serotyping of Organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex Full Text available with Trip Pro

Modification of Schaefer's Procedure for Serotyping of Organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex Modifications to the tube-agglutination procedure which Schaefer developed for serotyping of organisms of the Mycobacterium avium-M. intracellulare-M. scrofulaceum complex are proposed.

1972 Applied microbiology

160. Comparison of four culture media for isolation of Mycobacterium avium complex from porcine tissues. Full Text available with Trip Pro

Comparison of four culture media for isolation of Mycobacterium avium complex from porcine tissues. The efficiency of four culture media was compared for the isolation of Mycobacterium avium complex from 197 procine tissues. In 82 tissues with microscopic granulomas and acid-fast bacilli, a significantly greater number of isolates were obtained on Middlebrook 7H10 medium with sodium pyruvate than on Stonebrink medium, Herrold egg yolk agar medium, or Lowenstein-Jensen medium (P=0.01). In 46 (...) tissues in which no microscopic granulomas or acid-fast bacilli were observed, a significantly greater number of isolates were made on Middlebrook 7H10 medium or Herrold egg yolk agar medium than on Stonebrink medium or on Lowenstein-Jensen medium (P=0.01). The time required to grow M. avium complex on Lowenstein-Jensen medium was significantly greater than the time required to observe growth on Stonebrink, Middlebrook 7H10, or Herrold egg yolk agar medium (p=0.001).

1979 Journal of clinical microbiology

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