How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

1,142 results for

Mycobacterium Avium Complex

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

41. Meta-analyses and the evidence base for microbial outcomes in the treatment of pulmonary Mycobacterium avium-intracellulare complex disease. (PubMed)

Meta-analyses and the evidence base for microbial outcomes in the treatment of pulmonary Mycobacterium avium-intracellulare complex disease. To perform a systematic review and meta-analysis of the level of funding support and the sputum culture conversion rates in pulmonary Mycobacterium avium-intracellulare complex (P-MAC) disease in adult patients without cystic fibrosis or HIV infection, treated with recommended antibiotic regimens.We performed a literature search to identify clinical trials

Full Text available with Trip Pro

2017 The Journal of antimicrobial chemotherapy

42. Intermittent Antibiotic Therapy for Recurrent Nodular Bronchiectatic <i>Mycobacterium avium</i> Complex Lung Disease. (PubMed)

Intermittent Antibiotic Therapy for Recurrent Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease. Intermittent, three-times-weekly oral antibiotic therapy is recommended for the initial treatment of noncavitary nodular bronchiectatic (NB) Mycobacterium avium complex (MAC) lung disease. However, intermittent therapy is not recommended for patients who have been previously treated. We evaluated 53 patients with recurrent noncavitary NB MAC lung disease who underwent antibiotic

Full Text available with Trip Pro

2017 Antimicrobial Agents and Chemotherapy

43. Development and validation of a prognostic scoring model for Mycobacterium avium complex lung disease: an observational cohort study. (PubMed)

Development and validation of a prognostic scoring model for Mycobacterium avium complex lung disease: an observational cohort study. Patients with Mycobacterium avium complex (MAC) lung disease (LD) have a heterogeneous prognosis. This study aimed to develop and validate a prognostic scoring model for these patients using independent risk factors for survival.We retrospectively analyzed the data of patients with MAC-LD from two hospitals (cohort 1, n = 368; cohort 2, n = 118). Cohort 1

Full Text available with Trip Pro

2017 BMC Infectious Diseases

44. An association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation. (PubMed)

An association between pulmonary Mycobacterium avium-intracellulare complex infections and biomarkers of Th2-type inflammation. The rising incidence of pulmonary Mycobacterium avium-intracellulare complex (MAI) infection is unexplained but parallels the growing world-wide epidemic of allergic disease. We hypothesized an association between pulmonary MAI infection and Th2-type immune responses as seen in allergy.Biomarkers of patient Th2-type immune responses (peripheral blood eosinophil counts (...) and serum IgE levels) were compared between patients with positive pulmonary samples for tuberculosis and non-tuberculous mycobacterial (NTM) infection. A further comparison of clinical characteristics, including respiratory co-morbidities, and biomarkers, was conducted between patients culturing MAI NTM and those culturing NTM other than MAI.Patients culturing NTM from pulmonary samples had significantly higher peripheral blood eosinophil levels than those culturing Mycobacterium tuberculosis

Full Text available with Trip Pro

2017 Respiratory research

45. Microbiological persistence in patients with Mycobacterium avium complex lung disease: the predictors and the impact on radiographic progression. (PubMed)

Microbiological persistence in patients with Mycobacterium avium complex lung disease: the predictors and the impact on radiographic progression. Persistent growth of Mycobacterium avium complex (MAC) in the lungs indicates continuous infection in MAC lung disease (MAC-LD), but its clinical significance has not been investigated. We aimed to evaluate the predictors of persistent culture-positivity for MAC (MAC-PP) and its impact on radiographic deterioration in MAC-LD.Patients with MAC-LD

Full Text available with Trip Pro

2017 Clinical Infectious Diseases

46. Treatment Outcomes of Mycobacterium avium Complex Lung Disease: A Systematic Review and Meta-analysis. (PubMed)

Treatment Outcomes of Mycobacterium avium Complex Lung Disease: A Systematic Review and Meta-analysis. The advent of macrolides has led to therapeutic advances in the treatment of Mycobacterium avium complex lung disease (MAC-LD). The aim of this study was to elucidate the treatment outcomes of macrolide-containing regimens.We performed a systematic review and meta-analysis of published studies reporting treatment outcomes of macrolide-containing regimens for MAC-LD using the Medline, Embase

Full Text available with Trip Pro

2017 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

47. Impact of cavity and infiltration on pulmonary function and health-related quality of life in pulmonary Mycobacterium avium complex disease: A 3-dimensional computed tomographic analysis. (PubMed)

Impact of cavity and infiltration on pulmonary function and health-related quality of life in pulmonary Mycobacterium avium complex disease: A 3-dimensional computed tomographic analysis. Pulmonary Mycobacterium avium complex (pMAC) disease manifests as various types of lesions, such as infiltrates, nodules, cavities, and bronchiectasis. However, the important determinants for clinical parameters in lung involvement are poorly understood. The objective of this study was to obtain quantitative

2017 Respiratory medicine

48. Natural history of <i>Mycobacterium avium</i> complex lung disease in untreated patients with stable course. (PubMed)

Natural history of Mycobacterium avium complex lung disease in untreated patients with stable course. Little is known about the long-term natural history of Mycobacterium avium complex lung disease (MAC-LD) in untreated patients with stable course.The aim of this study was to investigate the natural course of untreated stable MAC-LD, with a focus on factors associated with clinical deterioration, spontaneous sputum conversion and prognosis.Of 488 patients diagnosed with MAC-LD between

Full Text available with Trip Pro

2017 European Respiratory Journal

49. Rapid pulmonary cavity formation caused by Mycobacterium avium complex in a chemotherapy patient (PubMed)

Rapid pulmonary cavity formation caused by Mycobacterium avium complex in a chemotherapy patient 29619321 2018 11 14 2214-2509 11 2018 IDCases IDCases Rapid pulmonary cavity formation caused by Mycobacterium avium complex in a chemotherapy patient. 39-40 10.1016/j.idcr.2017.12.007 Nakamura Ryo R Division of General Internal Medicine, Hashimoto Municipal Hospital, Hashimoto, Japan. Hashimoto Tadayuki T Division of General Internal Medicine, Hashimoto Municipal Hospital, Hashimoto, Japan. eng (...) Journal Article 2017 12 24 Netherlands IDCases 101634540 2214-2509 Chemotherapy Immunosuppressed patient Mycobacterium avium complex Pulmonary cavity lesion 2017 12 20 2017 12 21 2017 12 21 2018 4 6 6 0 2018 4 6 6 0 2018 4 6 6 1 epublish 29619321 10.1016/j.idcr.2017.12.007 S2214-2509(17)30249-4 PMC5881441 Arch Intern Med. 1976 Jan;136(1):67-70 1247337 Emerg Infect Dis. 2010 Oct;16(10):1576-83 20875283 Eur Respir J. 2017 Mar 8;49(3):null 28275170 Respir Investig. 2017 Jan;55(1):45-50 28012493 BMC Pulm

Full Text available with Trip Pro

2017 IDCases

50. CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier

2017 Clinical Trials

51. Successful diagnosis of intestinal Mycobacterium avium complex infection in a kidney transplant recipient using nasogastric aspirate culture: A case report (PubMed)

Successful diagnosis of intestinal Mycobacterium avium complex infection in a kidney transplant recipient using nasogastric aspirate culture: A case report Intestinal Mycobacterium avium complex (MAC) infections are rare and can be challenging to diagnose. We describe a case of intestinal MAC infection in a kidney transplant recipient with 5 months of unexplained weight loss and abdominal pain who developed intestinal obstruction. Esophagoduodenoscopy with biopsies was performed

Full Text available with Trip Pro

2017 Transplantation proceedings

52. Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant: A Silent and Coincidental Finding (PubMed)

Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant: A Silent and Coincidental Finding An 11-month-old healthy infant girl was noted to have left lower lobe (LLL) opacities on chest X-ray (CXR) after developing desaturations during an elective cochlear implant surgery. Repeat CXR 10 days later revealed hyperexpansion of the left lung and persistent LLL opacity. Chest computerized tomography revealed enlarged mediastinal lymph nodes, left mainstem bronchial obstruction (...) , and nodular opacities. Bronchoscopic biopsy of the endobronchial tissue revealed multiple necrotizing granulomas and grew Mycobacterium avium-intracellulare, Streptococcus viridans, and Actinomyces odontolyticus. This case illustrates the potential for significant mediastinal lymphadenopathy, and endobronchial and parenchymal lesions caused by nontuberculous mycobacteria, which can present insidiously and without respiratory symptoms in otherwise healthy infants, despite advanced pulmonary disease.

Full Text available with Trip Pro

2017 Pediatric allergy, immunology, and pulmonology

53. Attenuation of lymphocyte immune responses during Mycobacterium avium complex-induced lung disease due to increasing expression of programmed death-1 on lymphocytes (PubMed)

Attenuation of lymphocyte immune responses during Mycobacterium avium complex-induced lung disease due to increasing expression of programmed death-1 on lymphocytes Mycobacterium avium complex-induced lung disease (MAC-LD) becomes important due to its increasing prevalence. Attenuated cellular immunity associated with programmed cell death (PD)-1 may play a pathophysiological role in MAC-LD but lacks of investigation. We enrolled 80 participants in this prospective study, including 50 with MAC

Full Text available with Trip Pro

2017 Scientific reports

54. Infection Sources of a Common Non-tuberculous Mycobacterial Pathogen, Mycobacterium avium Complex (PubMed)

Infection Sources of a Common Non-tuberculous Mycobacterial Pathogen, Mycobacterium avium Complex Numerous studies have revealed a continuous increase in the worldwide incidence and prevalence of non-tuberculous mycobacteria (NTM) diseases, especially pulmonary Mycobacterium avium complex (MAC) diseases. Although it is not clear why NTM diseases have been increasing, one possibility is an increase of mycobacterial infection sources in the environment. Thus, in this review, we focused (...) with frequent human contact, such as soil and bathrooms, indicating that individuals may carry NTM organisms that concomitantly attach to their household belongings. To explore the mechanisms associated with the global spread of infection and MAC transmission routes, an epidemiological population-wide genotyping survey would be very useful. A good example of the power of genotyping comes from M. avium subsp. hominissuis, where close genetic relatedness was found between isolates of it from European patients

Full Text available with Trip Pro

2017 Frontiers in medicine

55. Levels of Antibody against Glycopeptidolipid Core as a Marker for Monitoring Treatment Response in Mycobacterium avium Complex Pulmonary Disease: a Prospective Cohort Study (PubMed)

Levels of Antibody against Glycopeptidolipid Core as a Marker for Monitoring Treatment Response in Mycobacterium avium Complex Pulmonary Disease: a Prospective Cohort Study The diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) is sometimes complicated and time-consuming. A serodiagnostic kit that measures the serum levels of IgA antibodies against the glycopeptidolipid (GPL) core is commercially available and has good diagnostic accuracy for MAC-PD. However, the significance

Full Text available with Trip Pro

2017 Journal of clinical microbiology

56. Incidence, Long-Term Outcomes, and Healthcare Utilization of Patients With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome and Disseminated Mycobacterium avium Complex From 1992–2015 (PubMed)

Incidence, Long-Term Outcomes, and Healthcare Utilization of Patients With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome and Disseminated Mycobacterium avium Complex From 1992–2015 Despite the advent of combination antiretroviral therapy (cART), patients with human immunodeficiency virus (HIV) continue to develop late-stage complications including acquired immune deficiency syndrome (AIDS), disseminated Mycobacterium avium complex (DMAC), and death.We performed (...) . Those with established HIV had a median time from HIV diagnosis to DMAC diagnosis of 7 years and were more likely to be black, rehospitalized in the 6 months after DMAC diagnosis, and die in the long term.Disseminated Mycobacterium avium complex continues to be a lethal diagnosis in the cART era, disproportionately afflicts minority populations, and reflects both delayed entry into care and failure to consistently engage care.

Full Text available with Trip Pro

2017 Open forum infectious diseases

57. A case of bilateral hilar and mediastinal lymphadenopathy developing during treatment for Mycobacterium avium complex (PubMed)

A case of bilateral hilar and mediastinal lymphadenopathy developing during treatment for Mycobacterium avium complex We report a rare case of an immunocompetent patient with Mycobacterium avium complex (MAC) disease in which bilateral hilar lymphadenopathy developed during anti-MAC treatment. This case indicates that Propionibacterium acnes would be present and might be a cause of sarcoidosis even in patients with MAC.

Full Text available with Trip Pro

2017 Clinical Case Reports

58. Disseminated Mycobacterium Avium Complex in an Adolescent with Perinatally-Acquired HIV Infection (PubMed)

Disseminated Mycobacterium Avium Complex in an Adolescent with Perinatally-Acquired HIV Infection Mycobacterium avium complex (MAC) is the most frequent nontuberculous mycobacteria implicated in opportunistic infections that define acquired immunodeficiency syndrome. With highly active antiretroviral therapy, disseminated MAC (dMAC) has become a rare entity. This unique case of dMAC was diagnosed in an adolescent with newly diagnosed perinatally-acquired HIV infection whose initial CD4 cell

Full Text available with Trip Pro

2017 Infectious disease reports

59. Hemophagocytic lymphohistiocytosis (HLH): Elusive diagnosis of disseminated Mycobacterium avium complex infection (PubMed)

Hemophagocytic lymphohistiocytosis (HLH): Elusive diagnosis of disseminated Mycobacterium avium complex infection Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome of hyperinflammation leading to an uncontrolled and ineffective immune response, associated with high mortality.A 26-year-old woman with acute lymphoblastic leukemia, 8 months in remission, was found to have HLH. Without any improvement, stem cell transplantation was considered. Then, Mycobacterium avium complex (MAC

Full Text available with Trip Pro

2017 Germs

60. A novel presentation of Mycobacterium avium complex in a recipient of a lung transplant: a case report (PubMed)

A novel presentation of Mycobacterium avium complex in a recipient of a lung transplant: a case report Lung transplantation remains an important potential therapeutic option for end-stage lung disease. It can improve quality of life and in some cases be a life-lengthening therapy. Despite the possible benefits, there are also many potential complications following transplantation. Here we describe a novel presentation of nontuberculous mycobacterium manifesting as an endobronchial mass (...) mycobacterium pulmonary disease is common post lung transplant and risk factors are related to immunosuppression and history of structural lung disease. Mycobacterium avium complex presenting as an endobronchial lesion in a patient post lung transplant is a novel presentation.

Full Text available with Trip Pro

2017 Journal of medical case reports

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>