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Murphy Sign

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121. Deployment of personnel to military operations: impact on mental health and social functioning Full Text available with Trip Pro

guards. Military reserve forces are members of the armed forces who combine a civil career with a military career. Reserve forces have a signed contract with the military and may be called in for active duty if needed. At any given time the demand for military personnel affects which subpopulation is at risk of deployment. For instance, at times of low demand only members of the Active Component face risk of deployment, whereas under times of high demand, such as for example under Operation Enduring

2018 Campbell Collaboration

122. Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review Full Text available with Trip Pro

, 12‐Step meetings and counseling, recreational activities and social events, life‐skills training, educational supports and peer and family support, as well as linkages to community supports and services ( ; ; ). Some CRCs also require that members sign a behavioral and sobriety contract that may be implemented and enforced by a peer governance system ( ). Similar to RHSs, some CRCs also have admission criteria for their community programs. For example, one CRC at a large public university

2018 Campbell Collaboration

124. How can health care workers help patients with a health condition and/or disability remain in or get back into work?

, and leads to better health outcomes. Where physically possible, people suffering from long-term conditions (LTCs) often benefit from returning to work, as it can improve their quality of life and well-being, by reducing social exclusion and poverty (6). Long periods out of work can sometimes create greater health problems than the original diagnosis. For example, when a patient is signed off sick, they no longer see their work colleagues, and this can lead to depression. Often, with reasonable (...) described multi-component programmes. The authors of this paper concluded that not How can health care workers help patients with a health condition and/or disability remain in or get back into work? KLS Evidence Briefing 31 st January 2018 much robust evidence is available on this topic, and warned about making decisions based on the findings. ? Psychosocial Flags are warning signs that highlight psychosocial factors that might cause obstacles to the recovery of an individual. Yellow flags are patient

2018 Public Health England - Evidence Briefings

125. Quality indicators for the management of head and neck squamous cell carcinoma

status SIGN Scottish Intercollegiate Guidelines Network TNM Tumour – Node – Metastasis UK United Kingdom US(A) United States (of America) UZ – CHU University hospital (‘Universitair ziekenhuis’/‘Centre hospitalier universitair’) WHO World Health Organization WUHNCI Washington University Head and Neck Comorbidity Index X Missing stage 22 Quality indicators for the management of HNSCC KCE Report 305 ? SCIENTIFIC REPORT 1 INTRODUCTION Since several years, the Belgian Health Care Knowledge Centre (KCE

2019 Belgian Health Care Knowledge Centre

128. Epigenetics and Reproductive Medicine Full Text available with Trip Pro

for the transition to independent life . Cell Metab 2012 ; 15 : 209 – 21 . 23 Morison, IM , Reeve, AE . A catalogue of imprinted genes and parent‐of‐origin effects in humans and animals . Hum Mol Genet 1998 ; 7 : 1599 – 609 . 24 Skaar, DA , Li, Y , Bernal, AJ , Hoyo, C , Murphy, SK , Jirtle, RL . The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility . ILAR J 2012 ; 53 : 341 – 58 . 25 Eggermann, T , Perez de Nanclares, G , Maher, ER , Temple, IK , Tumer, Z (...) Soubry, A , Hoyo, C , Jirtle, RL , Murphy, SK . A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line . BioEssays 2014 ; 36 : 359 – 71 . 97 Shea, JM , Serra, RW , Carone, BR , Shulha, HP , Kucukural, A , Ziller, MJ , et al. Genetic and epigenetic variation, but not diet, shape the sperm methylome . Dev Cell 2015 ; 35 : 750 – 8 . 98 Batcheller, A , Cardozo, E , Maguire, M , DeCherney, AH , Segars, JH . Are there subtle genome‐wide epigenetic alterations

2018 Royal College of Obstetricians and Gynaecologists

129. Placenta Praevia and Placenta Accreta: Diagnosis and Management Full Text available with Trip Pro

to massive haemorrhage. Similarly, a prospective cohort study of 54 women with placenta praevia covering the internal os has shown that combining a cervical length of less than 30 mm and measurement of the lower placental edge thickness of more than 10 mm has a sensitivity of 83.3% and a specificity of 78.4%. More prospective studies using a standardised ultrasound definition of placental edge thickness are required before this sign can be used in clinical practice. [Evidence level 2+] Compared (...) of ultrasound signs (see Appendix ) used for the prenatal diagnosis of placenta accreta and the International Abnormally Invasive Placenta Expert Group produced a proforma protocol for the ultrasound assessment. Evidence level 4 A systematic review and meta‐analysis of 23 ultrasound studies including 3707 pregnancies at risk of placenta accreta found that the overall performance of ultrasound when performed by skilled operators was very good with a sensitivity of 90.72% (95% CI 87.2–93.6), specificity

2018 Royal College of Obstetricians and Gynaecologists

130. Public health guidance on active case finding of communicable diseases in prison settings

for testing, at entrance and/or during stay (including at release) Active TB Active tuberculosis (TB) refers to disease that occurs in someone infected with Mycobacterium tuberculosis. It is characterised by signs or symptoms of active disease, or both, and is distinct from latent TB infection, which occurs without signs or symptoms of active disease Client-initiated testing Testing which is voluntary and performed as the result of a person’s health- seeking behaviour, triggered by symptoms development (...) the interests of any commercial body, Member State, or professional body. All panel members signed declarations of interest, which were reviewed by ECDC’s compliance officer. None of the members of the panel SCIENTIFIC ADVICE Public health guidance on active case finding of communicable diseases in prison settings 9 declared a conflict of interest. The panel was chaired by one of its members, and ECDC and EMCDDA acted as secretariat. The scientific panel held four teleconferences and one face-to-face

2018 European Centre for Disease Prevention and Control - Public Health Guidance

131. Considerations for the clinical management of HIV elite controllers

. 2012;119(20):4645–55. Dahl V, Peterson J, Spudich S, Lee E, Shacklett BL, Price RW, et al. Single-copy assay quantification of HIV-1 RNA in paired cerebrospinal fluid and plasma samples from elite controllers. AIDS. 2013;27(7):1145–9. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, et al. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. AIDS. 2014;28(16):2439–49. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, et (...) Rapid Response Service. Considerations for the clinical management of elite controllers. Toronto, ON: Ontario HIV Treatment Network; June, 2018. Prepared by David Gogolishvili and Jean Bacon Photo credit Ontario HIV Treatment Network 1300 Yonge Street, Suite 600 Toronto ON M4T 1X3 416-642-6486 Please enter your search terms Sign up for our monthly newsletter Get our “Did you know” — our monthly newsletter, and updates and announcements from the OHTN. Name Email Opt into another list Research

2018 Ontario HIV Treatment Network

133. Recommendations for the Delivery of Psychosocial Oncology Services in Ontario

in Cancer More than 40 percent of all cancer patients will develop significant distress at some point during diagnosis, treatment, survivorship, progression of disease, palliation or end of life (8) . One recent study (16) identified high levels of distress in 52 percent of cancer patients over a range of tumour sites. Distress has been called the “sixth vital sign” (17) , and persistent severe distress can have negative implications for patients, including reduced health- related quality of life, poor (...) satisfaction with medical care and possibly reduced survival (8, 18) . Screening for distress as the 6th vital sign is considered a standard through Accreditation Canada (19) . Examples of distress include issues such as depression, anxiety (including extreme fear of recurrence) and body image disturbance, which may or may not be associated with sexual health problems. These difficulties can contribute to an inability to return to work and relationship problems with family members and friends, in turn

2018 Cancer Care Ontario

135. Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV

. Journal of the International AIDS Society. 2016;19(1):20903. Lal L, Audsley J, Murphy D, Fairley CK, Stoove M, Roth N, et al. Medication adherence, condom use and sexually transmitted infections in Australian PrEP users: Interim results from the Victorian PrEP Demonstration Project. AIDS. 2017;01:01. Blaylock JM, Hakre S, Decker CF, Wilson B, Bianchi E, Michael N, et al. HIV PrEP in the military: Experience at a tertiary care military medical center. Military Medicine. 2018;183(suppl_1):445–9. Marcus (...) reservoir despite continued antiretroviral therapy. Journal of the International AIDS Society. 2014;17(4 Suppl 3):19731. Suggested citation Rapid Response Service. Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV. Toronto, ON: Ontario HIV Treatment Network; October 2018. Prepared by Michelle Camilleri and David Gogolishvili Photo credit Ontario HIV Treatment Network 1300 Yonge Street, Suite 600 Toronto ON M4T 1X3 416-642-6486 Please enter your search terms Sign up for our monthly newsletter

2018 Ontario HIV Treatment Network

137. Treating Opioid Use Disorder During Pregnancy: Guideline Supplement

, a common dose reduction immediately post-par- tum for patients taking methadone is 20% of the total daily dose; however, empirical evidence supporting this pre-determined dose reduction convention is limited. 74,75 Endorsing frequent visits for monitoring for at least 12 weeks post-partum, a number of studies demonstrate that gradual and individualized dose reductions informed by observed signs of over-sedation may more suitable for maintaining the mother’s stability during this period. 75-77 In some

2018 British Columbia Perinatal Health Program

138. Recommendation on screening adults for asymptomatic thyroid dysfunction in primary care

in asymptomatic nonpregnant adults is not likely to confer clinical benefit, but could lead to unnecessary treatment for some patients and consume resources. Treating asymptomatic adults for screen-detected hypothyroidism may result in little to no difference in clinical outcomes. Clinicians should remain alert to signs and symptoms suggestive of thyroid dysfunction and investigate accordingly. This guideline from the Canadian Task Force on Preventive Health Care focuses on screening for thyroid dysfunction (...) among asymptomatic nonpregnant adults in primary care beyond usual care and vigilance for signs and symptoms of thyroid dysfunction. Thyroid dysfunction is diagnosed based on abnormal levels of serum thyroid-stimulating hormone (TSH) and can be characterized as either hypo- or hyperthyroidism. Hypothyroidism results from impaired thyroid hormone production (i.e., thyroxine [T 4 ] or triiodothyronine [T 3 ]), leading to elevated levels of TSH. Hypothyroidism is often caused by autoimmune disorders

2019 Canadian Task Force on Preventive Health Care

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