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Muehrcke Line

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1. Muehrcke Line

Muehrcke Line Muehrcke Line Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Muehrcke Line Muehrcke Line Aka: Muehrcke Line (...) , Muehrcke's Line From Related Chapters II. Pathophysiology Abnormality of vascular nail bed III. Causes Hypoalbuminemia (<2g/dl) IV. Signs: Transverse Linear Nail Lesion Parallel, narrow horizontal (transverse) white lines at nail bed Lines do not move with (involves nail bed, not the nail plate) Lines disappear when nail plate is depressed Lines resolve with treatment of hypoalbuminemia (if that was the underlying cause) V. Differential Diagnosis s (move with ) VI. Reference Images: Related links

2018 FP Notebook

2. Muehrcke Lines of the Fingernails (Diagnosis)

Muehrcke Lines of the Fingernails (Diagnosis) Muehrcke Lines of the Fingernails: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNjQyMy1vdmVydmlldw== processing > Muehrcke (...) Lines of the Fingernails Updated: Jun 08, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Muehrcke Lines of the Fingernails Overview Background Muehrcke lines are paired, white, transverse lines that signify an abnormality in the vascular bed of the nail. Muehrcke first described paired, narrow, white, transverse fingernail lines in a series of 65 patients with severe, chronic hypoalbuminemia. [ ] He believed that the lines

2014 eMedicine.com

3. Muehrcke Lines of the Fingernails (Overview)

Muehrcke Lines of the Fingernails (Overview) Muehrcke Lines of the Fingernails: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNjQyMy1vdmVydmlldw== processing > Muehrcke (...) Lines of the Fingernails Updated: Jun 08, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Muehrcke Lines of the Fingernails Overview Background Muehrcke lines are paired, white, transverse lines that signify an abnormality in the vascular bed of the nail. Muehrcke first described paired, narrow, white, transverse fingernail lines in a series of 65 patients with severe, chronic hypoalbuminemia. [ ] He believed that the lines

2014 eMedicine.com

4. Muehrcke Lines of the Fingernails (Treatment)

Muehrcke Lines of the Fingernails (Treatment) Muehrcke Lines of the Fingernails Treatment & Management: Medical Care, Long-Term Monitoring Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNjQyMy10cmVhdG1lbnQ (...) = processing > Muehrcke Lines of the Fingernails Treatment & Management Updated: Jun 08, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Muehrcke Lines of the Fingernails Treatment Medical Care Treatment should be undertaken in a case-specific manner. In patients presenting with paired, white, transverse lines due to a serum albumin deficiency, albumin infusions to raise the serum level aid in the disappearance of Muehrcke lines

2014 eMedicine.com

5. Muehrcke Lines of the Fingernails (Follow-up)

Muehrcke Lines of the Fingernails (Follow-up) Muehrcke Lines of the Fingernails Treatment & Management: Medical Care, Long-Term Monitoring Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEwNjQyMy10cmVhdG1lbnQ (...) = processing > Muehrcke Lines of the Fingernails Treatment & Management Updated: Jun 08, 2018 Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD Share Email Print Feedback Close Sections Sections Muehrcke Lines of the Fingernails Treatment Medical Care Treatment should be undertaken in a case-specific manner. In patients presenting with paired, white, transverse lines due to a serum albumin deficiency, albumin infusions to raise the serum level aid in the disappearance of Muehrcke lines

2014 eMedicine.com

6. Muehrcke lines (PubMed)

Muehrcke lines 22927514 2013 05 06 2018 11 13 1488-2329 185 5 2013 Mar 19 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Muehrcke lines. E239 10.1503/cmaj.120269 Sharma Vishal V Department of Medicine, University College of Medical Sciences, Delhi, India. docvishalsharma@gmail.com Kumar Vivek V eng Case Reports Journal Article 2012 08 27 Canada CMAJ 9711805 0820-3946 AIM IM Humans Hypertension, Portal complications diagnosis Liver Cirrhosis

Full Text available with Trip Pro

2013 CMAJ : Canadian Medical Association Journal

7. Muehrcke Line

Muehrcke Line Muehrcke Line Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Muehrcke Line Muehrcke Line Aka: Muehrcke Line (...) , Muehrcke's Line From Related Chapters II. Pathophysiology Abnormality of vascular nail bed III. Causes Hypoalbuminemia (<2g/dl) IV. Signs: Transverse Linear Nail Lesion Parallel, narrow horizontal (transverse) white lines at nail bed Lines do not move with (involves nail bed, not the nail plate) Lines disappear when nail plate is depressed Lines resolve with treatment of hypoalbuminemia (if that was the underlying cause) V. Differential Diagnosis s (move with ) VI. Reference Images: Related links

2015 FP Notebook

8. Fingernails changes associated with chemotherapy in breast cancer: Muehrcke’s lines (PubMed)

Fingernails changes associated with chemotherapy in breast cancer: Muehrcke’s lines Nail abnormalities are an indicator of systemic disease but are always neglected during clinic visit. Here, we report a rare case of Muehrcke's lines accompany with normal range serum albumin after chemotherapy, unlike the hypoalbuminemia in most cases, which suggest malnutrition is not the only cause of Muehrcke's lines.

Full Text available with Trip Pro

2018 Clinical Case Reports

9. Muehrcke’s lines (PubMed)

Muehrcke’s lines 29588909 2018 11 14 2236-1960 8 1 2018 Jan-Mar Autopsy & case reports Autops Case Rep Muehrcke's lines. e2018014 10.4322/acr.2018.014 Tavares Nuno Teixeira NT Centro Hospitalar de São João, Serviço de Oncologia Médica. Porto, Portugal. Costa Andreia A Centro Hospitalar de São João, Serviço de Oncologia Médica. Porto, Portugal. Damasceno Margarida M Centro Hospitalar de São João, Serviço de Oncologia Médica. Porto, Portugal. eng Journal Article 2018 03 02 Brazil Autops Case

Full Text available with Trip Pro

2018 Autopsy & Case Reports

10. Drug induced longitudinal melanonychia and transverse muerhcke's lines. (PubMed)

Drug induced longitudinal melanonychia and transverse muerhcke's lines. 29730887 2018 11 29 1468-3083 32 12 2018 Dec Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Drug-induced longitudinal melanonychia and transverse muehrcke's lines. e462-e463 10.1111/jdv.15060 di Meo N N Department of Dermatology, University of Trieste, Trieste, Italy. Longone M M Department of Dermatology, University of Trieste, Trieste, Italy. Retrosi C C Department

2018 Journal of the European Academy of Dermatology and Venereology

11. Membranous nephropathy

and exam presence of risk factors oedema elevated BP incidental proteinuria or abnormal renal function xanthelasma foamy urine fatigue/malaise anorexia Muehrcke's lines male sex age >40 years HLA-DR3 autoimmune disease hepatitis B and C syphilis solid organ carcinoma medications sarcoidosis post-renal transplantation Diagnostic investigations urinalysis urine protein to creatinine ratio serum urea serum creatinine creatinine clearance serum albumin lipid profile serum or plasma LFTs hepatitis B and C

2019 BMJ Best Practice

12. Membranous nephropathy

and exam presence of risk factors oedema elevated BP incidental proteinuria or abnormal renal function xanthelasma foamy urine fatigue/malaise anorexia Muehrcke's lines male sex age >40 years HLA-DR3 autoimmune disease hepatitis B and C syphilis solid organ carcinoma medications sarcoidosis post-renal transplantation Diagnostic investigations urinalysis urine protein to creatinine ratio serum urea serum creatinine creatinine clearance serum albumin lipid profile serum or plasma LFTs hepatitis B and C

2017 BMJ Best Practice

13. Focal segmental glomerulosclerosis

creatinine, the morphological subtype, the degree of renal fibrosis, and the response to therapy. Definition Focal segmental glomerulosclerosis (FSGS) is a chronic pathological process caused by injury to podocytes in the renal glomeruli. It manifests initially with proteinuria, which progresses to nephrotic syndrome and ultimately to end-stage renal failure. History and exam presence of risk factors oedema foamy urine hypertension Muehrcke's lines xanthelasma and xanthomata BMI 95th percentile (...) response to decreased renal mass. May be asymptomatic or present with nephrotic syndrome. First-line therapy in primary focal segmental glomerulosclerosis with nephrotic-range proteinuria is corticosteroid therapy. Secondary form requires treatment of the underlying cause. Corticosteroid-dependent and corticosteroid-resistant patients require treatment with other immunosuppressants such as ciclosporin. Prognosis is extremely variable and depends on the amount of proteinuria, the level of plasma

2017 BMJ Best Practice

15. Dental Treatment to Correct Dental Caries in Patients Undergoing Surgery: A Review of Clinical Evidence on Safety

associated risk factor for blood-borne infection in patients undergoing major surgery. 1,2 Dental chronic infections such as periodontitis, periapical lesions or advanced carious lesions can cause the development of infective endocarditis, an infection of the inner lining of the heart chambers and valves. 1,3 Blood-borne bacteria may lodge on damaged or abnormal heart valve tissues causing this specific type of inflammation. 3 There is a general agreement that dental treatment is desirable before heart (...) ;79(1):34- 45. 2. Berbari EF, Osmon DR, Carr A, Hanssen AD, Baddour LM, Greene D, et al. Dental procedures as risk factors for prosthetic hip or knee infection: a hospital-based prospective case-control study. Clin Infect Dis. 2010 Jan 1;50(1):8-16. 3. Terezhalmy GT, Safadi TJ, Longworth DL, Muehrcke DD. Oral disease burden in patients undergoing prosthetic heart valve implantation. Ann Thorac Surg. 1997 Feb;63(2):402-4. 4. Yasny JS, Silvay G. The value of optimizing dentition before cardiac

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

16. Prevention and Treatment of Thrombosis in Pediatric and Congenital Heart Disease

), children with acquired heart disease, and in adults with CHD. High-risk groups include patients with shunt- dependent single ventricles (shunt thrombosis, 8%–12%; 4% risk of death resulting from shunt failure), postoperative central lines (13% thrombosis in central venous lines [CVLs]), Fontan circulation (17%–33% incidence of thrombosis after Fontan), arrhythmias, Kawasaki disease with coronary aneurysms, and cardiomyopathy/myocarditis. Although the prevalence, risk factors, and management of some (...) into degradation products (FDPs). Right , Factor XIIIa, thrombin-activatable fibrinolysis inhibitor (TAFIa), plasminogen activator inhibitor type 1 (PAI-1), and α2-antiplasmin promote fibrin stability. The dotted lines indicate inhibition of thrombin (IIa) formation or thrombin activity by tissue factor pathway inhibitor (TFPI), antithrombin III (ATIII), and activated protein C (APC) in the presence of protein S (PS). TM indicates thrombomodulin. Adapted from Becker and reproduced with kind permission from

2013 American Heart Association

17. 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines

, it is necessary to update and revise guideline recommenda- tionsfromtimetotime.TheSocietyofThoracicSurgeons recommends review and possible update of previously published guidelines at least every three years. This summary is an update of the blood conservation guide- line published in 2007. Methods. The search methods used in the current version differ compared to the previously published guideline.Literaturesearcheswereconductedusingstan- dardized MeSH terms from the National Library of Medicine PUBMED

2011 Society of Thoracic Surgeons

19. Ventricular Septal Rupture Following Myocardial Infarction (Treatment)

if frank papillary muscle rupture is present Trim the left ventricular margins back to viable muscle Conservatively trim the right ventricular muscle Close the VSR without tension, using prosthetic material Buttress the suture line with Teflon pledgets Percutaneous techniques have been used successfully to close some congenital VSDs. Technical improvements in experimental devices for closing intracardiac shunts are being made to treat postinfarction VSR or residual shunts after primary repair (...) Surg . 1986 Jun. 41(6):683-91. . Daggett WM, Buckley MJ, Akins CW, et al. Improved results of surgical management of postinfarction ventricular septal rupture. Ann Surg . 1982 Sep. 196(3):269-77. . Muehrcke DD, Daggett WM. Current surgical approach to acute ventricular septal rupture. Adv Card Surg . 1995. 6:69-90. . Serpytis P, Karvelyte N, Serpytis R, Kalinauskas G, Rucinskas K, Samalavicius R, et al. Post-infarction ventricular septal defect: risk factors and early outcomes. Hellenic J Cardiol

2014 eMedicine Surgery

20. Ventricular Septal Rupture Following Myocardial Infarction (Follow-up)

if frank papillary muscle rupture is present Trim the left ventricular margins back to viable muscle Conservatively trim the right ventricular muscle Close the VSR without tension, using prosthetic material Buttress the suture line with Teflon pledgets Percutaneous techniques have been used successfully to close some congenital VSDs. Technical improvements in experimental devices for closing intracardiac shunts are being made to treat postinfarction VSR or residual shunts after primary repair (...) Surg . 1986 Jun. 41(6):683-91. . Daggett WM, Buckley MJ, Akins CW, et al. Improved results of surgical management of postinfarction ventricular septal rupture. Ann Surg . 1982 Sep. 196(3):269-77. . Muehrcke DD, Daggett WM. Current surgical approach to acute ventricular septal rupture. Adv Card Surg . 1995. 6:69-90. . Serpytis P, Karvelyte N, Serpytis R, Kalinauskas G, Rucinskas K, Samalavicius R, et al. Post-infarction ventricular septal defect: risk factors and early outcomes. Hellenic J Cardiol

2014 eMedicine Surgery

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