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Mortons Neuroma Injection

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1. Short term comparison between blind and ultrasound guided injection in morton neuroma. (Abstract)

Short term comparison between blind and ultrasound guided injection in morton neuroma. The aim of this work is to compare the effectiveness of blind and ultrasound-guided injection for Morton's neuroma (MN) to determine which is more appropriate as the initial procedure in conservative treatment.This is an evaluator-blinded randomised trial. Of the 56 included patients, 27 were assigned to the blind group (A) and 29 to the ultrasound-guided group (B). Injection includes 1 ml of 2% mepivacaine (...) .• Ultrasound-guided steroid injections in Morton's neuroma provide short-term pain relief to over 60% of the patients. • Ultrasound-guided injections in Morton's neuroma lead to a higher percentage of short-term pain relief than blind injections. • Ultrasound-guided injections in Morton's neuroma lead to a lower percentage of skin side effects than blind injections.

2019 European radiology Controlled trial quality: uncertain

2. Corticosteroid Injection for the Treatment of Morton's Neuroma: A Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial Full Text available with Trip Pro

Corticosteroid Injection for the Treatment of Morton's Neuroma: A Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial The effectiveness of corticosteroid injection for the treatment of Morton's neuroma is unclear. In addition, most of the studies related to it are case-control or retrospective case series. The purpose of this study was to compare the effectiveness between corticosteroid injection associated with local anesthetic and local anesthetic alone (placebo control group (...) ) for the treatment of Morton's neuroma.Forty-one patients with a diagnosis of Morton's neuroma were randomized to receive 3 injections of either a corticosteroid plus a local anesthetic or a local anesthetic alone. The patients and the researcher who collected data were blinded to the treatment groups. The visual analog scale for pain and the American Orthopaedic Foot & Ankle Score (metatarsophalangeal/interphalangeal score) were obtained at baseline, after each injection, and at 3 and 6 months after the last

2017 EvidenceUpdates

3. Radiofrequency ablation for symptomatic interdigital (Morton's) neuroma

include details of patient selection and previous treatments. Studies should compare the procedure against other non-surgical treatments, such as steroid injections. Outcome measures should include pain relief, the duration of treatment effect, and the need for subsequent treatments. 2 2 Indications and current treatments Indications and current treatments 2.1 Symptomatic interdigital (Morton's) neuroma is caused by perineural fibrosis which creates scar tissue, resulting in compression (...) of an interdigital nerve. It usually occurs between the metatarsal heads of the third and fourth toes but can sometimes occur between the second and third toes. Symptoms include severe intermittent pain, a burning sensation, and paraesthesia in the front part of the sole of the foot, extending into the toes. 2.2 Initial management of symptomatic Morton's neuroma includes rest, anti-inflammatory medications, using an orthosis in the shoe and wearing a different type of shoe. Injection of steroids and local

2016 National Institute for Health and Clinical Excellence - Interventional Procedures

4. Ultrasound-Guided Hyaluronic Acid Injection for the Management of Morton's Neuroma. (Abstract)

Ultrasound-Guided Hyaluronic Acid Injection for the Management of Morton's Neuroma. Morton's neuroma is one of the common causes of forefoot pain. In the present study, hyaluronic acid injection was performed on patients to determine the efficacy and adverse effects of hyaluronic acid in management of Morton's neuroma.Eighty-three patients with Morton's neuroma in their third intermetatarsal space with definite Mulder's click were included in the study. Those with severe forefoot deformities (...) , continuing until 12 months. The mean VAS was decreased from 73.1 initially to 23.0 at 12 months and AOFAS Forefoot Scale was increased from 32.2 to 86.5. There were no complications which occurred.In the present study, ultrasound-guided hyaluronic injection was clinically effective for pain relief and functional improvement for at least 12 months in patients with Morton's neuroma. However, numbness associated with Morton's neuroma should be addressed more cautiously since it may persist without much

2017 Foot & Ankle International

5. Morton's Neuroma Injection

Morton's Neuroma Injection Mortons Neuroma Injection Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Morton's Neuroma Injection (...) Morton's Neuroma Injection Aka: Morton's Neuroma Injection , Interdigital Neuroma Injection II. Indications refractory to other measures III. Preparation Needle Gauge: 25 to 27 Length: 1.0 to 1.5 inches Syringe: 3 to 5 ml options (Celestone) 0.5 ml of 6 mg/ml (Solu-medrol): 0.5 ml of 40 mg/ml Anesthetic 1%: 1 to 2 ml or 0.25% or 0.5%: 1 to 2 ml IV. Technique Patient position Supine position with knee flexed over towel roll in neutral position Landmarks Interdigital space between heads Mark area maximal

2018 FP Notebook

6. Economic evaluation of corticosteroid injections for mortons neuroma

Economic evaluation of corticosteroid injections for mortons neuroma Economic evaluation corticosteroid injections mortons neuroma Search National Elf Service Search National Elf Service » » » » Economic evaluation of corticosteroid injections for mortons neuroma Mar 26 2015 Posted by Mortons neuroma is a common cause of forefoot pain. Those who are troubled by this affliction of the plantar nerve usually describe pain and numbness extending from the ball of the foot into the toes. Current (...) treatments include footwear advice, insoles, corticosteroid injection and in some cases surgical excision of the nerve. This new paper from the Journal of Foot and Ankle Research ( Open Access ) examines cost-effectiveness of steroid (methylprednisolone) injections versus anaesthetic alone for the treatment of Morton’s neuroma: economic evaluation alongside a randomised controlled trial (MortISE trial). Here’s what they did The authors carried out this work in conjunction with a randomised controlled

2015 The Musculoskeletal Elf

7. A randomized, double blind, placebo controlled trial of injected capsaicin for pain in Morton's neuroma. (Abstract)

A randomized, double blind, placebo controlled trial of injected capsaicin for pain in Morton's neuroma. Intermetatarsal neuroma or Morton's neuroma is a painful condition of the foot resulting from an entrapment of the common digital nerve typically in the third intermetatarsal space. The pain can be severe and especially problematic with walking. Treatment options are limited and surgery may lead to permanent numbness in the toes. Capsaicin, the pungent ingredient of hot peppers, produces (...) analgesia by inducing retraction of nociceptive afferents from the area of innervation and is effective in treating certain neuropathic pain disorders. A randomized double-blind placebo-controlled study was conducted to test the efficacy, tolerability, and safety of a single 0.1 mg dose of capsaicin vs placebo injected into the region of the neuroma. A total of 58 subjects diagnosed with Morton's neuroma with foot pain ≥4 (0-10 numerical pain rating scale) were injected with 2 mL of lidocaine

2016 Pain Controlled trial quality: predicted high

8. Corticosteroid injection for Morton's neuroma with or without ultrasound guidance: a randomised controlled trial. (Abstract)

Corticosteroid injection for Morton's neuroma with or without ultrasound guidance: a randomised controlled trial. The objective of this double-blind randomised controlled trial was to assess whether ultrasound guidance improved the efficacy of corticosteroid injections for Morton's neuroma (MN).In all, 50 feet (40 patients) were recruited for this study but five feet were excluded due to the patients declining further participation. The mean age of the remaining 36 patients (45 feet) was 57.8 (...) years (standard deviation (sd) 12.9) with a female preponderance (33F:12M). All patients were followed-up for 12 months. Treatment was randomised to an ultrasound guided (Group A) or non-ultrasound guided (Group B) injection of 40 mg triamcinolone acetonide and 2 ml 1% lignocaine, following ultrasound confirmation of the diagnosis.The mean visual analogue score for pain improved significantly in both groups (Group A - from 64 mm, sd 25 mm to 29 mm, sd 27; Group B - from 69 mm, sd 23 mm to 37 mm, sd

2016 The Bone & Joint Journal Controlled trial quality: predicted high

9. Blind and Ultrasound Guided Injection in Morton Neuroma

Blind and Ultrasound Guided Injection in Morton Neuroma Blind and Ultrasound Guided Injection in Morton Neuroma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Blind and Ultrasound Guided Injection (...) de Granada Information provided by (Responsible Party): FERNANDO RUIZ SANTIAGO, Complejo Hospitalario Universitario de Granada Study Details Study Description Go to Brief Summary: The aim of this work trial is to compare the effectiveness of blind and ultrasound guided injection for Morton neuroma in order to determine which is more appropriate as the initial procedure in conservative treatment Condition or disease Intervention/treatment Phase Morton Neuroma Device: blind injection of Morton

2016 Clinical Trials

10. Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma

Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Compare Ultrasound Assisted Cold Therapy and Lidocaine Injection to Treat Morton's Neuroma The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02838758 Recruitment Status : Completed First Posted : July 20, 2016 Last Update Posted : November 6, 2018 Sponsor: Icahn School

2016 Clinical Trials

11. Cost-effectiveness of steroid (methylprednisolone) injections versus anaesthetic alone for the treatment of Morton's neuroma: economic evaluation alongside a randomised controlled trial (MortISE trial). Full Text available with Trip Pro

Cost-effectiveness of steroid (methylprednisolone) injections versus anaesthetic alone for the treatment of Morton's neuroma: economic evaluation alongside a randomised controlled trial (MortISE trial). Morton's neuroma is a common foot condition affecting health-related quality of life. Though its management frequently includes steroid injections, evidence of cost-effectiveness is sparse. So, we aimed to evaluate whether steroid injection is cost-effective in treating Morton's neuroma compared (...) with anaesthetic injection alone.We undertook incremental cost-effectiveness and cost-utility analyses from the perspective of the National Health Service, alongside a patient-blinded pragmatic randomised trial in hospital-based orthopaedic outpatient clinics in Edinburgh, UK. Of the original randomised sample of 131 participants with Morton's neuroma (including 67 controls), economic analysis focused on 109 (including 55 controls). Both groups received injections guided by ultrasound. We estimated

2015 Journal of foot and ankle research Controlled trial quality: predicted high

12. Morton's neuroma

such as corticosteroid injection or surgery. Have I got the right topic? Have I got the right topic? From age 16 years onwards. This CKS topic covers the management of Morton's neuroma (also known as Morton's metatarsalgia, Morton's entrapment, interdigital neuroma, intermetatarsal neuroma, and interdigital nerve compression syndrome). This CKS topic does not cover the management of other causes of metatarsalgia. The target audience for this CKS topic is healthcare professionals working within the NHS in the UK (...) Morton's neuroma Morton's neuroma - NICE CKS Share Morton's neuroma: Summary Morton's neuroma is a benign fibrotic thickening of a plantar interdigital nerve that is a response to irritation. Also known as Morton's metatarsalgia, Morton's entrapment, interdigital neuroma, intermetatarsal neuroma, and interdigital nerve compression syndrome, it is not a true neuroma, as the condition is a degenerative process rather than a neoplastic process. Mechanisms thought to cause irritation of the nerve

2016 NICE Clinical Knowledge Summaries

13. A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)

A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02678793 Recruitment Status

2016 Clinical Trials

14. Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)

Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Study to Evaluate the Safety and Tolerability of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02550756 Recruitment Status

2015 Clinical Trials

15. A systematic review of ultrasound-guided and non-ultrasound-guided therapeutic injections to treat Morton's neuroma. (Abstract)

A systematic review of ultrasound-guided and non-ultrasound-guided therapeutic injections to treat Morton's neuroma. Morton's neuroma is a frequently painful condition of the forefoot, causing patients to seek medical care to alleviate symptoms. A plethora of therapeutic options is available, some of which include injection therapies. Researchers have investigated injection therapy for Morton's neuroma, and latterly the evidence base has been augmented with methods that use diagnostic (...) be considered for injection therapy in the management of Morton's neuroma.

2014 Journal of the American Podiatric Medical Association

16. A Systematic Review of Ultrasound-Guided and Non Ultrasound-Guided Therapeutic Injections to treat Morton's neuroma. (Abstract)

A Systematic Review of Ultrasound-Guided and Non Ultrasound-Guided Therapeutic Injections to treat Morton's neuroma. Abstract BACKGROUND:Morton's neuroma is a frequently painful condition of the forefoot, causing sufferers to seek medical care to alleviate symptoms. A plethora of therapeutic options are available, some of which include injection therapies. Researchers have investigated injection therapy for Morton's neuroma, and latterly the evidence base has been augmented with methodologies (...) which utilise diagnostic ultrasound (US) as a vehicle to deliver the injectate under image guidance for additional accuracy. There appears to date to be no consensus that US-guided injections provide better therapeutic outcomes than non US-guided (blind) injections for treatment of Morton's neuroma. METHODS:A systematic review was chosen, as this methodology can undertake such a process. The review process identified 13 key papers using pre-determined inclusion and exclusion criteria, which

2014 Journal of the American Podiatric Medical Association

17. Morton's Neuroma: Manipulation Versus Steroid Injection

Morton's Neuroma: Manipulation Versus Steroid Injection Morton's Neuroma: Manipulation Versus Steroid Injection - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Morton's Neuroma: Manipulation Versus Steroid (...) Information provided by (Responsible Party): David Cashley, Queen Margaret University Study Details Study Description Go to Brief Summary: The aim of this study is to establish which of two treatment options is the preferred intervention in the treatment of Morton's Neuroma. A randomised controlled trial shall be performed. Steroid injection is the current gold standard conservative treatment for this condition. Therefore, manipulation shall be compared to a control group receiving a steroid injection

2014 Clinical Trials

18. Effects of Alcohol Injection in Rat Sciatic Nerve as a Model for Morton's Neuroma Treatment. Full Text available with Trip Pro

Effects of Alcohol Injection in Rat Sciatic Nerve as a Model for Morton's Neuroma Treatment. Previous studies have shown that the injection of dehydrated alcohol has been successful for the treatment of Morton's neuroma in the foot. In this study, we determined the cellular effect of injection of alcohol into and around the sciatic nerve of rats and measured the extent of cell necrosis and/or any associated histologic or inflammatory changes.Twenty-two male (~375 g) Wistar rats were randomized (...) injections in the treatment of Morton's neuroma in human clinical practice.© The Author(s) 2014.

2014 Foot & Ankle International Controlled trial quality: uncertain

19. Ultrasound-Guided Alcohol Injection for Morton's Neuroma. (Abstract)

Ultrasound-Guided Alcohol Injection for Morton's Neuroma. Ultrasonography-guided alcohol injection (USGAI) of Morton's neuroma represents an alternative to operative treatment. Nonetheless, the literature only reports few small studies evaluating the effectiveness of the treatment. The aim of the present retrospective study was to assess the effectiveness of USGAI to treat Morton's neuroma in 508 patients at 2 medical centers.Between January 2001 and January 2012, 508 patients with 540 Morton's (...) neuroma had USGAI for Morton's neuroma. Only second and third web-space neuromas were included in this study.A mean number of 3.0 (range, 1 to 4) injections were performed for each neuroma. Mean local inflammatory reaction was 0.7 (range, 0 to 2). There were no other local or systemic complications. The overall mean pre-USGAI VAS score was 8.7 (range, 6 to 10), while the post-USGAI VAS score at 1 year was 3.6 (range, 0 to 9). The delta VAS between the pre- and post-USGAI was statistically significant

2014 Foot & Ankle International

20. Injected corticosteroids for treating Morton's neuroma pain in adults: a systematic review and meta-analysis of randomised and non-randomised controlled trials (Protocol)

Injected corticosteroids for treating Morton's neuroma pain in adults: a systematic review and meta-analysis of randomised and non-randomised controlled trials (Protocol) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2016 PROSPERO

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