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Mononeuropathy in Diabetes

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1. Assessment of lower extremity mononeuropathy

of the peripheral nerve, from the dorsal root ganglion through to the lumbosacral plexus and the terminal individual named nerves. Dysfunction can lead to weakness, pain, or sensory deficits. These entities are a major source of neurological referral. Causes Mononeuropathies can be thought of as compressive or idiopathic, or as sequelae of underlying systemic disease (e.g., diabetes, malignancy, infection, and inflammatory conditions). Compressive neuropathies produce symptoms in the distribution (...) Assessment of lower extremity mononeuropathy Assessment of lower extremity mononeuropathy - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of lower extremity mononeuropathy Last reviewed: February 2019 Last updated: June 2018 Summary Mononeuropathies of the lower extremities are commonly encountered in clinical practice. A mononeuropathy may result from pathology located anywhere along the course

2018 BMJ Best Practice

2. Do we underestimate influences of diabetic mononeuropathy or polyneuropathy on hand functional performance and life quality? (PubMed)

Do we underestimate influences of diabetic mononeuropathy or polyneuropathy on hand functional performance and life quality? The purpose of the present study was to identify whether there are differences in hand dexterity, hand functional performance and quality of life between diabetes patients with mononeuropathy and polyneuropathy of their hands to further present the importance regarding the impacts of diabetic neuropathic deficits on patients' functional capacity.The neurological deficits (...) of 127 patients with type 2 diabetes were examined by electrophysiological tests for the median and ulnar nerves, and were stratified into the diabetic mononeuropathy, diabetic polyneuropathy and non-diabetic neuropathy groups by sensory amplitude of these nerves. The Purdue pegboard test, Michigan Hand Outcomes Questionnaire, and Diabetes-39 were carried out to understand patients' hand dexterity, functional hand performance and quality of life, respectively.The results showed significant

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2017 Journal of Diabetes Investigation

3. Mononeuropathy in Diabetes

Mononeuropathy in Diabetes Mononeuropathy in Diabetes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Mononeuropathy in Diabetes (...) Mononeuropathy in Diabetes Aka: Mononeuropathy in Diabetes , Diabetic Mononeuropathy , Diabetic Focal Neuropathy II. Background Subtype of Sudden onset large nerve involvement Associated with nerve infarction III. Distribution: Common areas effected ( ) Loss of finger flexion and grip ( ) drop (deep peroneal nerve, L4-L5) Recurrent laryngeal nerve palsy ( , , ) Ophthalmoplegia, , yet PERRLA ( ) Affected eye slightly more elevated ( ) Affected eye deviated medially ( ) ( ) IV. Course Often resolves

2018 FP Notebook

4. Distal Mononeuropathy Before and After Arthroscopic Rotator Cuff Repair: A Prospective Investigation. (PubMed)

Distal Mononeuropathy Before and After Arthroscopic Rotator Cuff Repair: A Prospective Investigation. The purpose of this study was to characterize the occurrence of distal mononeuropathy (DMN) in patients before and after arthroscopic rotator cuff repair (RCR) as well as resolution of the symptoms.One hundred one patients over the age of 18 undergoing arthroscopic RCR +/- concurrent procedures completed a questionnaire regarding the presence of a symptomatic DMN. Patients with history (...) of diabetic neuropathy, cervical radiculopathy, brachial plexopathy, or Spurling sign were excluded. All patients underwent physical examination to determine the characteristics and location of symptoms. Postoperatively, patients underwent repeat examination at 2, 6, and 12 weeks.Preoperatively, 19% (19/101) of RCR patients described DMN symptoms (9 median nerve symptoms, 5 ulnar nerve symptoms, 4 nonspecific symptoms, one with both ulnar and median nerve symptoms). Ninety percent (17/19) patients

2018 Arthroscopy

5. Sensory Potentials and Ultrasonography in Common Peroneal Mononeuropathy

Sensory Potentials and Ultrasonography in Common Peroneal Mononeuropathy Sensory Potentials and Ultrasonography in Common Peroneal Mononeuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Sensory (...) Potentials and Ultrasonography in Common Peroneal Mononeuropathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03753178 Recruitment Status : Completed First Posted : November 26, 2018 Last Update Posted : November 27, 2018 Sponsor: rania sanad Information provided by (Responsible Party): rania sanad

2018 Clinical Trials

6. Diabetic neuropathy

Diabetic neuropathy Diabetic neuropathy - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Diabetic neuropathy Last reviewed: February 2019 Last updated: April 2018 Summary Hyperglycaemia contributes to the pathogenesis of neuropathy in both type 1 and type 2 diabetes. Other metabolic and vascular factors, particularly hypertriglyceridaemia, are important. The clinical presentation comprises a broad constellation (...) of symptoms and deficits, involving sensory, motor, and autonomic nerve fibres, and multiple organ systems. Diabetic peripheral neuropathy is the most common chronic complication of diabetes, characterised by the presence of peripheral nerve dysfunction, diagnosed after the exclusion of other causes. Pain is the outstanding complaint in most patients, but many patients are completely asymptomatic. Treatment has traditionally focused on control of hyperglycaemia as a means of slowing progression

2018 BMJ Best Practice

7. Mononeuropathy in Diabetes

Mononeuropathy in Diabetes Mononeuropathy in Diabetes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Mononeuropathy in Diabetes (...) Mononeuropathy in Diabetes Aka: Mononeuropathy in Diabetes , Diabetic Mononeuropathy , Diabetic Focal Neuropathy II. Background Subtype of Sudden onset large nerve involvement Associated with nerve infarction III. Distribution: Common areas effected ( ) Loss of finger flexion and grip ( ) drop (deep peroneal nerve, L4-L5) Recurrent laryngeal nerve palsy ( , , ) Ophthalmoplegia, , yet PERRLA ( ) Affected eye slightly more elevated ( ) Affected eye deviated medially ( ) ( ) IV. Course Often resolves

2015 FP Notebook

8. Femoral Mononeuropathy (Overview)

Femoral Mononeuropathy (Overview) Femoral Mononeuropathy: Background, Anatomy, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE0MTc5My1vdmVydmlldw== processing > Femoral Mononeuropathy Updated: Jun 08 (...) , 2018 Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE Share Email Print Feedback Close Sections Sections Femoral Mononeuropathy Overview Background Femoral mononeuropathy can occur secondary to direct trauma, compression, stretch injury, or ischemia. The condition causes weakness predominantly of the quadriceps, which results in difficulty with ambulation. Femoral nerve compression may result in debilitating pain, requiring medical therapy and surgical

2014 eMedicine.com

9. Femoral Mononeuropathy (Diagnosis)

Femoral Mononeuropathy (Diagnosis) Femoral Mononeuropathy: Background, Anatomy, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE0MTc5My1vdmVydmlldw== processing > Femoral Mononeuropathy Updated: Jun 08 (...) , 2018 Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE Share Email Print Feedback Close Sections Sections Femoral Mononeuropathy Overview Background Femoral mononeuropathy can occur secondary to direct trauma, compression, stretch injury, or ischemia. The condition causes weakness predominantly of the quadriceps, which results in difficulty with ambulation. Femoral nerve compression may result in debilitating pain, requiring medical therapy and surgical

2014 eMedicine.com

10. Femoral Mononeuropathy (Treatment)

Femoral Mononeuropathy (Treatment) Femoral Mononeuropathy Treatment & Management: Approach Considerations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE0MTc5My10cmVhdG1lbnQ= processing > Femoral Mononeuropathy (...) Treatment & Management Updated: Jun 08, 2018 Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE Share Email Print Feedback Close Sections Sections Femoral Mononeuropathy Treatment Approach Considerations Treatment is dependent on the etiology of the lesion. As previously stated, most patients with a femoral mononeuropathy can be treated conservatively with physical therapy, avoidance of excessive hip abduction and external rotation, and knee bracing to prevent

2014 eMedicine.com

11. Femoral Mononeuropathy (Follow-up)

Femoral Mononeuropathy (Follow-up) Femoral Mononeuropathy Treatment & Management: Approach Considerations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTE0MTc5My10cmVhdG1lbnQ= processing > Femoral Mononeuropathy (...) Treatment & Management Updated: Jun 08, 2018 Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE Share Email Print Feedback Close Sections Sections Femoral Mononeuropathy Treatment Approach Considerations Treatment is dependent on the etiology of the lesion. As previously stated, most patients with a femoral mononeuropathy can be treated conservatively with physical therapy, avoidance of excessive hip abduction and external rotation, and knee bracing to prevent

2014 eMedicine.com

12. Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy

Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove (...) one or more studies before adding more. Study of PEMF to Evaluate VPT and Thermal Sensory in Subjects With Diabetic Peripheral Neuropathy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03077893 Recruitment Status : Completed First Posted : March 13, 2017 Last Update Posted : April 11, 2018 Sponsor

2017 Clinical Trials

13. Trazodone in Painful Diabetic Neuropathy

Trazodone in Painful Diabetic Neuropathy Trazodone in Painful Diabetic Neuropathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Trazodone in Painful Diabetic Neuropathy The safety and scientific validity (...) Francesco S.p.A Study Details Study Description Go to Brief Summary: The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep, quality of life, safety and tolerability. Condition or disease Intervention/treatment Phase Painful Diabetic Neuropathy Drug: Trazodone 20 mg Drug: Trazodone 10 mg Drug: Placebo Phase 2 Detailed Description

2017 Clinical Trials

14. Electrospun Nanofibers Loaded with Quercetin Promote the Recovery of Focal Entrapment Neuropathy in a Rat Model of Streptozotocin-Induced Diabetes (PubMed)

Electrospun Nanofibers Loaded with Quercetin Promote the Recovery of Focal Entrapment Neuropathy in a Rat Model of Streptozotocin-Induced Diabetes In this study, quercetin-loaded zein-based nanofibers were developed using electrospinning technique. The therapeutic effect of these quercetin-loaded nanofibers on neuropathy in streptozotocin- (STZ-) induced diabetes in rats was assessed. Diabetic condition was induced in male Wistar rats by STZ, after which a crush injury of the right sciatic (...) nerve was performed to induce mononeuropathy. Functional recovery was assessed using walking track analysis, measurements of foot withdrawal reflex, nerve conduction velocity, and morphological analysis. The oxidative stress status and the ratio of phosphorylated extracellular recognition kinase (pERK)/extracellular recognition kinase (ERK) expression in the nerve lesion were also assessed in order to elucidate the potential mechanisms involved. Results showed that quercetin-loaded zein-based

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2017 BioMed research international

15. Primary Care Corner with Geoffrey Modest MD: Diabetic Neuropathy Guidelines

(food consumption, and occasionally just the smell of food, leading to sweating of head and neck area) Other neuropathies: Mononeuropathies: especially of median, ulnar, radial and common peroneal nerves. cranial neuropathies are rare but include cranial nerves III, IV, VI, VII and usually resolve spontaneously over months Diabetic radiculoplexus neuropathy (also called diabetic amyotrophy): unilateral thigh pain, weight loss, followed by motor weakness. self-limited (though I have a type 1 diabetic (...) Primary Care Corner with Geoffrey Modest MD: Diabetic Neuropathy Guidelines Primary Care Corner with Geoffrey Modest MD: Diabetic Neuropathy Guidelines | BMJ EBM Spotlight by By Dr. Geoffrey Modest The American Diabetes Association just came out with their position paper on diabetic neuropathy (see DOI: 10.2337/dc16-2042). I will limit my points to type 2 diabetes, though type 1 is covered in this paper Summary of points: Diabetic neuropathy is a diagnosis of exclusion: diabetic patients may

2017 Evidence-Based Medicine blog

16. Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)

Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP) Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum (...) number of saved studies (100). Please remove one or more studies before adding more. Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pain (DPNP) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02673866 Recruitment Status : Withdrawn

2016 Clinical Trials

17. Correlation of Michigan neuropathy screening instrument, United Kingdom screening test and electrodiagnosis for early detection of diabetic peripheral neuropathy (PubMed)

 %) and 91 (73 %) of patients, respectively. There was a significant relationship between number of neuropathies and mean of diabetes duration and development of retinopathy in both questionnaire evaluations and NCS. By nerve conduction study, neuropathy was detected in 121 (97 %) diabetic patients were reported in order 15 (12 %) mononeuropathy (as 33 % sensory and 67 % motor neuropathy) and 106 (85 %) polyneuropathy (as 31 % motor and 69 % sensorimotor neuropathy).As regards NCS is an objective, simple (...) Correlation of Michigan neuropathy screening instrument, United Kingdom screening test and electrodiagnosis for early detection of diabetic peripheral neuropathy Almost half of Diabetic Peripheral Neuropathies (DPNs) are symptom-free. Methods including questionnaires and electrodiagnosis (EDx) can be fruitful for easy reach to early diagnosis, correct treatments of diabetic neuropathy, and so decline of complications for instance diabetic foot ulcer and prevention of high costs. The goal of our

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2016 Journal of diabetes and metabolic disorders

18. Diabetic Neuropathy

OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) Definition (CSP) common complication of diabetes mellitus in which nerves are damaged as a result of hyperglycemia (high blood sugar levels). Concepts Disease or Syndrome ( T047 ) MSH ICD9 250.6 SnomedCT 267472008 , 154683002 , 193182005 , 866003 , 190349003 , 190353001 (...) Diabetic Neuropathy Diabetic Neuropathy Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Diabetic Neuropathy Diabetic Neuropathy Aka

2018 FP Notebook

19. Multiple Mononeuropathy

, diabetes usually causes sensorimotor distal polyneuropathy. Multiple mononeuropathies are characterized by pain, weakness, and paresthesias in the distribution of the affected nerves. Pure motor nerve involvement begins with painless weakness; pure sensory nerve involvement begins with sensory disturbances and no weakness. Multiple mononeuropathy is often asymmetric at first; nerves may be involved all at once or progressively. Extensive involvement of many nerves may simulate polyneuropathy. Symptoms (...) Multiple Mononeuropathy Multiple Mononeuropathy - Neurologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / OTHER TOPICS IN THIS CHAPTER Test your knowledge Other Neurologic Imaging

2013 Merck Manual (19th Edition)

20. Mononeuropathies

Mononeuropathies Mononeuropathies - Neurologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Other Neurologic Imaging (...) Studies The use of cerebral catheter angiography has dramatically decreased with the advent of which of the following? CT angiography Duplex Doppler ultrasonography Echoencephalography Myelography NEWS & VIDEOS GDM Linked to Increased Cardiovascular Event Risk Postpartum FRIDAY, March 8, 2019 (HealthDay News) -- Women with gestational diabetes mellitus (GDM) have an increased risk fir developing cardiovascular events postpartum, according to a review published... 3D Model Herniated Nucleus Pulposus

2013 Merck Manual (19th Edition)

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