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Mongolian Spot

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21. Sirens to Scrubs: Acute Coronary Syndromes, Part Four – Spot the Lesion!

Sirens to Scrubs: Acute Coronary Syndromes, Part Four – Spot the Lesion! Sirens to Scrubs: Acute Coronary Syndromes, Part Four - Spot the Lesion! - CanadiEM Sirens to Scrubs: Acute Coronary Syndromes, Part Four – Spot the Lesion! In , by Paula Sneath January 8, 2019 In of this series, we reviewed the pathophysiology of Acute Coronary Syndromes (ACS), as well as some of the important features that should be elucidated on history-taking. In we discussed the current evidence-based practices (...) a very intuitive view – it’s taken from the left side of the heart, looking up from the feet. It is also called the “spider view”.) (The view of the left coronary arteries from the left side of the heart, looking down from the head) (The view of the left coronary arteries from the right side of the heart, looking up from the feet) (The view of the left coronary arteries from the right side of the heart, looking down from the head) Spot the Lesion! Got all that? Let’s try applying some pattern

2019 CandiEM

22. Cutis marmorata telangiectatica congenita and aberrant Mongolian spots: Type V phacomatosis pigmentovascularis or phacomatosis cesiomarmorata Full Text available with Trip Pro

Cutis marmorata telangiectatica congenita and aberrant Mongolian spots: Type V phacomatosis pigmentovascularis or phacomatosis cesiomarmorata 27051820 2016 04 07 2019 02 26 2352-5126 2 1 2016 Jan JAAD case reports JAAD Case Rep Cutis marmorata telangiectatica congenita and aberrant Mongolian spots: Type V phacomatosis pigmentovascularis or phacomatosis cesiomarmorata. 28-30 10.1016/j.jdcr.2015.10.006 Du Guilian G Neonatology Department, the Fifth People's Hospital of Baoan, Shenzhen, China (...) . Zhang Xiaomin X Department of Dermatology and STD, Changping Hospital of Dongguan and Zhujiang Hospital, Guangzhou, China. Zhang Tangde T Department of Dermatology and STD, Changping Hospital of Dongguan and Zhujiang Hospital, Guangzhou, China. eng Case Reports 2016 01 23 United States JAAD Case Rep 101665210 2352-5126 CMTC, Cutis marmorata telangiectatica congenita Cutis marmorata telangiectatica congenital Mongolian spots PPV, Phacomatosis pigmentovascularis phacomatosis phacomatosis

2016 JAAD Case Reports

23. Spot the Diagnosis! The Case of Mona Lisa Full Text available with Trip Pro

Spot the Diagnosis! The Case of Mona Lisa Spot the Diagnosis! The Case of Mona Lisa - CanadiEM Spot the Diagnosis! The Case of Mona Lisa In , by Tetyana Maniuk January 6, 2018 Mona Lisa – Da Vinci (Click here for full sized image) This is one of the most famous paintings in the world. Various medical diagnoses float around regarding the subject of this painting; was she missing her teeth and that is what caused her tight lipped smile? Or was it a result of facial paralysis? However, there may (...) be physical signs of one intriguing diagnosis. Can you spot it? While you’re giving it some thought, please consider taking 5 minutes to give us feedback on the “Spot the Diagnosis!” series. From newcomers to loyal fans, we would love to hear about ! What are the physical exam findings? The subject of this painting is a young woman – likely in her 20’s to 30’s. She is sitting straight up, with arms folded, and maintaining appropriate eye contact with the viewer. She is smiling with her mouth closed. When

2018 CandiEM

24. First trimester Down syndrome screening with dried blood spots using a dual analyte free beta hCG and PAPP-A immunofluorometric assay. (Abstract)

First trimester Down syndrome screening with dried blood spots using a dual analyte free beta hCG and PAPP-A immunofluorometric assay. To determine the effectiveness of first trimester Down syndrome screening with dried blood spots using a dual analyte free beta human chorionic gonadotrophin (hCG)/pregnancy-associated plasma protein A (PAPP-A) immunofluorometric assay.An initial retrospective study of 54 Down syndrome cases and 1064 control specimens was performed followed by a series (...) % between 9 and 13 weeks of gestation. Adjusting distribution parameters based on the routine screening dataset reduced the detection rate by at most 1%.Analysis of free beta hCG and PAPP-A using a dual analyte dried blood spot assay is an effective tool in Down syndrome screening, adding an important option for those considering implementation or modification of existing prenatal screening programs.Copyright © 2011 John Wiley & Sons, Ltd.

2011 Prenatal diagnosis

25. Temporal and spatial distribution characteristics in the natural plague foci of Chinese Mongolian gerbils based on spatial autocorrelation Full Text available with Trip Pro

2005 to 2014 and host density data of the study area from 2005 to 2010 used in this study were provided by Chinese Center for Disease Control and Prevention.The epidemic focus regions of the Mongolian gerbils remain the same as the hot spot regions relating to the body flea index. High clustering areas possess a similar pattern as the distribution pattern of the body flea index indicating that the transmission risk of plague is relatively high. In terms of time series, the area of the epidemic (...) of Mongolian gerbils by body flea index from 2005 to 2014, in order to predict plague outbreaks.Global spatial autocorrelation was used to describe the entire spatial distribution pattern of the body flea index in the natural plague foci of typical Chinese Mongolian gerbils. Cluster and outlier analysis and hot spot analysis were also used to detect the intensity of clusters based on geographic information system methods. The quantity of M. unguiculatus nest fleas in the sentinel surveillance sites from

2017 Infectious diseases of poverty

26. Endemic prevalence of hepatitis B and C in Mongolia: A nationwide survey among Mongolian adults. (Abstract)

Endemic prevalence of hepatitis B and C in Mongolia: A nationwide survey among Mongolian adults. In this study, a representative group of Mongolian adults was tested for hepatitis B virus (HBV) and hepatitis C virus (HCV). Screening was conducted at 17 different locations on a randomly sampled group, representing the Mongolian adult population. A total of 1158 adults, 500 (43.1%) men and 659 (56.9%) women were included. The prevalence estimates of HBV and HCV amongst the general Mongolian adult (...) estimate of the prevalence of HBV in Mongolia and also considered the first for HCV since 2005 and confirm the position of Mongolia as one of the hot-spots of chronic hepatitis infection in the world with about 19.4% of the adult population being infected with either HBV or HCV.© 2017 John Wiley & Sons Ltd.

2017 Journal of viral hepatitis

27. Transcriptome analysis of Macrobrachium rosenbergii intestines under the white spot syndrome virus and poly (I:C) challenges. Full Text available with Trip Pro

Transcriptome analysis of Macrobrachium rosenbergii intestines under the white spot syndrome virus and poly (I:C) challenges. Intestine is a primary site of the white spot syndrome virus (WSSV) infection in most crustaceans. To date, little is known about its role in the anti-viral immune response in the freshwater prawn Macrobrachium rosenbergii. In this study, next-generation sequencing was employed to investigate the M. rosenbergii intestine transcriptomes following WSSV or poly I:C (...) greater than the down-regulated DEGs. Gene Ontology (GO) classification of the DEGs also distributed similarly, with the same top 10 annotations and were all assigned to the signaling pathways, including spliceosome, Rap1 signaling pathway, proteoglycans, PI3K-Akt signaling pathway, ECM receptor interaction. Results could contribute to a better understanding of the intestinal immune response to viral pathogens.

2018 PLoS ONE

28. A transcriptome study on Macrobrachium nipponense hepatopancreas experimentally challenged with white spot syndrome virus (WSSV). Full Text available with Trip Pro

A transcriptome study on Macrobrachium nipponense hepatopancreas experimentally challenged with white spot syndrome virus (WSSV). White spot syndrome virus (WSSV) is one of the most devastating pathogens of cultured shrimp, responsible for massive loss of its commercial products worldwide. The oriental river prawn Macrobrachium nipponense is an economically important species that is widely farmed in China and adult prawns can be infected by WSSV. However, the molecular mechanisms of the host (...) and classified into 63 functional groups. Approximately, 4,311 differential expression genes were identified with 3,308 genes were up-regulated when comparing the survived samples with the control. In the comparison of moribund samples with control, 1,960 differential expression genes were identified with 764 genes were up-regulated. In the contrast of two comparison libraries, 300 mutual DEGs with 95 up-regulated genes and 205 down-regulated genes. All the DEGs were performed GO and KEGG analysis, overall

2018 PLoS ONE

29. Mongolian Spot (Diagnosis)

on 203 healthy neonates in a Brazilian public hospital, a greater incidence was found in nonwhite, black, and Asian babies. [ ] A case-controlled study conducted in Turkey on 50 patients with Down syndrome showed that Mongolian spot was among the most common mucocutaneous disorders; it was seen in 22% of patients and in 6% of healthy controls with a P -value of 0.018. [ ] Race Mongolian spots are observed in more than 90% of infants of the Mongoloid race (ie, East Asians, Indonesians, Polynesians (...) , Mostafa H. Incidence of Mongolian spots and its common sites at two university hospitals in Tehran, Iran. Pediatr Dermatol . 2010 Jul-Aug. 27(4):397-8. . Zagne V, Fernandes NC. Dermatoses in the first 72 h of life: A clinical and statistical survey. Indian J Dermatol Venereol Leprol . 2011 Jul-Aug. 77(4):470-6. . Bilgili SG, Akdeniz N, Karadag AS, Akbayram S, Calka O, Ozkol HU. Mucocutaneous disorders in children with down syndrome: case-controlled study. Genet Couns . 2011. 22(4):385-92

2014 eMedicine.com

30. Mongolian Spot (Overview)

on 203 healthy neonates in a Brazilian public hospital, a greater incidence was found in nonwhite, black, and Asian babies. [ ] A case-controlled study conducted in Turkey on 50 patients with Down syndrome showed that Mongolian spot was among the most common mucocutaneous disorders; it was seen in 22% of patients and in 6% of healthy controls with a P -value of 0.018. [ ] Race Mongolian spots are observed in more than 90% of infants of the Mongoloid race (ie, East Asians, Indonesians, Polynesians (...) , Mostafa H. Incidence of Mongolian spots and its common sites at two university hospitals in Tehran, Iran. Pediatr Dermatol . 2010 Jul-Aug. 27(4):397-8. . Zagne V, Fernandes NC. Dermatoses in the first 72 h of life: A clinical and statistical survey. Indian J Dermatol Venereol Leprol . 2011 Jul-Aug. 77(4):470-6. . Bilgili SG, Akdeniz N, Karadag AS, Akbayram S, Calka O, Ozkol HU. Mucocutaneous disorders in children with down syndrome: case-controlled study. Genet Couns . 2011. 22(4):385-92

2014 eMedicine.com

31. Mongolian Spot (Treatment)

Mar. 14 (3):301-2. . Ochiai T, Ito K, Okada T, Chin M, Shichino H, Mugishima H. Significance of extensive Mongolian spots in Hunter's syndrome. Br J Dermatol . 2003 Jun. 148(6):1173-8. . Mimouni-Bloch A, Finezilber Y, Rothschild M, Raas-Rothschild A. Extensive Mongolian Spots and Lysosomal Storage Diseases. J Pediatr . 2016 Mar. 170:333-e1. . Snow TM. Mongolian spots in the newborn: do they mean anything?. Neonatal Netw . 2005 Jan-Feb. 24(1):31-3. . Ziegler A, Guichet A, Pinson L, Barth M, Levade (...) T, Bonneau D, et al. Extensive Mongolian spots in 4p16.3 deletion (Wolf-Hirschhorn syndrome). Clin Dysmorphol . 2014 Jul. 23 (3):109-10. . Sharawat IK, Saini L, Randhawa MS, Ahuja CK. Extensive Mongolian spots and normocephaly: an uncommon presentation of infantile Sandhoff's disease. BMJ Case Rep . 2018 Jul 30. 2018: . Köse O, Huseynov S, Demiriz M. Giant Mongolian macules with bilateral ocular involvement: case report and review. Dermatology . 2012. 224(2):126-9. . Ma H, Liao M, Qiu S, Luo R

2014 eMedicine.com

32. Mongolian Spot (Follow-up)

Mar. 14 (3):301-2. . Ochiai T, Ito K, Okada T, Chin M, Shichino H, Mugishima H. Significance of extensive Mongolian spots in Hunter's syndrome. Br J Dermatol . 2003 Jun. 148(6):1173-8. . Mimouni-Bloch A, Finezilber Y, Rothschild M, Raas-Rothschild A. Extensive Mongolian Spots and Lysosomal Storage Diseases. J Pediatr . 2016 Mar. 170:333-e1. . Snow TM. Mongolian spots in the newborn: do they mean anything?. Neonatal Netw . 2005 Jan-Feb. 24(1):31-3. . Ziegler A, Guichet A, Pinson L, Barth M, Levade (...) T, Bonneau D, et al. Extensive Mongolian spots in 4p16.3 deletion (Wolf-Hirschhorn syndrome). Clin Dysmorphol . 2014 Jul. 23 (3):109-10. . Sharawat IK, Saini L, Randhawa MS, Ahuja CK. Extensive Mongolian spots and normocephaly: an uncommon presentation of infantile Sandhoff's disease. BMJ Case Rep . 2018 Jul 30. 2018: . Köse O, Huseynov S, Demiriz M. Giant Mongolian macules with bilateral ocular involvement: case report and review. Dermatology . 2012. 224(2):126-9. . Ma H, Liao M, Qiu S, Luo R

2014 eMedicine.com

33. Multiple and superimposed Mongolian spots Full Text available with Trip Pro

Multiple and superimposed Mongolian spots 24014338 2014 04 11 2018 11 13 1757-790X 2013 2013 Sep 06 BMJ case reports BMJ Case Rep Multiple and superimposed Mongolian spots. 10.1136/bcr-2013-200740 bcr2013200740 Musumeci Maria Letizia ML Department of Dermatology, University of Catania, Catania, Italy. Lacarrubba Francesco F Santagati Cecilia C Micali Giuseppe G eng Case Reports Journal Article 2013 09 06 England BMJ Case Rep 101526291 1757-790X IM Humans Infant, Newborn Male Mongolian Spot

2013 BMJ case reports

34. Mongolian spots: How important are they? Full Text available with Trip Pro

Mongolian spots: How important are they? Mongolian spots (MS) are congenital birthmarks seen most commonly over the lumbosacral area. They are bluish-green to black in color and oval to irregular in shape. They are most commonly found in individuals of African or Asian ethnic background. Although these lesions resolve by one to two years of age, widespread, extrasacral and dark colored MS sometimes persist into adulthood. Aberrant MS over occiput, temple, mandibular area, shoulders and limbs (...) may be confused with other dermal melanocytoses and bruises secondary to child abuse, thus necessitating documentation at birth. Although traditionally believed to be benign in nature, they have now been shown to co-exist with inborn errors of metabolism, most commonly GM1 gangliosidosis and mucopolysaccharidosis type I (Hurler's disease), followed by mucopolysaccharidosis type II (Hunter's syndrome), mucolipidosis, Niemann-Pick disease and mannosidosis. They have also been seen to co-exist

2013 World Journal of Clinical Cases : WJCC

35. Mongolian Spot

Mongolian Spot Mongolian Spot Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Mongolian Spot Mongolian Spot Aka: Mongolian Spot (...) , 40467008 Swedish Mongolfläck Czech mongolská skvrna , Mongolská skvrna Finnish Mongoliläiskä Italian Chiazza mongolica blu , Macchia mongolica , Chiazza mongolica Russian MONGOL'SKOE PIATNO , МОНГОЛЬСКОЕ ПЯТНО English Mongolian spots (physical finding) , Mongolian spots , Mongolian spots were observed , Mongolian Spot [Disease/Finding] , mongolian blue spot , mongolian spot , mongolian spots , blue mongolian spots , Spots - mongolian , Blue sacral spot , Mongolian macula , Mongolian spot , Mongolian

2015 FP Notebook

36. The Significance of Brushfield's Spots in the Diagnosis of Mongolism in Infancy Full Text available with Trip Pro

The Significance of Brushfield's Spots in the Diagnosis of Mongolism in Infancy 14904092 2004 02 15 2018 12 01 0003-9888 26 130 1951 Dec Archives of disease in childhood Arch. Dis. Child. The significance of Brushfield's spots in the diagnosis of mongolism in infancy. 495-500 WALLIS H R E HR eng Journal Article England Arch Dis Child 0372434 0003-9888 OM Down Syndrome Humans 5221:34676:240 MONGOLISM 1951 12 1 1951 12 1 0 1 1951 12 1 0 0 ppublish 14904092 PMC1988487 Br J Ophthalmol. 1949 Mar;33

1951 Archives of Disease in Childhood

37. Dystrophin gene expression and intracellular calcium changes in the giant freshwater prawn, Macrobrachium rosenbergii, in response to white spot symptom disease infection Full Text available with Trip Pro

Dystrophin gene expression and intracellular calcium changes in the giant freshwater prawn, Macrobrachium rosenbergii, in response to white spot symptom disease infection Dystrophin, an essential protein functional in the maintenance of muscle structural integrity is known to be responsible for muscle deterioration during white spot syndrome virus (WSSV) infection among prawn species. Previous studies have shown the upregulation of dystrophin protein in Macrobrachium rosenbergii (the giant (...) freshwater prawn) upon white spot syndrome virus (WSSV) infection. The literature has also suggested the important role of calcium ion alterations in causing such muscle diseases. Thus, the interest of this study lies within the linkage between dystrophin functioning, intracellular calcium and white spot syndrome virus (WSSV) infection condition.In this study, the dystrophin gene from M. rosenbergii (MrDys) was first characterised followed by the characterization of dystrophin gene from a closely related

2018 Heliyon

38. Differential gene expression in leaf tissues between mutant and wild-type genotypes response to late leaf spot in peanut (Arachis hypogaea L.). Full Text available with Trip Pro

was selected from an interspecific cross of cultivar Baisha 1016 with A. diogoi, and is resistant to several fungal diseases. By contrast, the M14 was highly susceptible to late leaf spot. RNA-Seq analysis in the leaf tissues of the M14 and its wild type Yuanza 9102 under pathogen challenge showed 2219 differentially expressed genes including1317 up-regulated genes and 902 down-regulated genes. Of these genes, 1541, 1988, 1344, 643 and 533 unigenes were obtained and annotated by public protein databases (...) Differential gene expression in leaf tissues between mutant and wild-type genotypes response to late leaf spot in peanut (Arachis hypogaea L.). Late leaf spot (LLS) is a major foliar disease in peanut (A. hypogaea L.) worldwide, causing significant losses of potential yield in the absence of fungicide applications. Mutants are important materials to study the function of disease-related genes. In this study, the mutant line M14 was derived from cultivar Yuanza 9102 treated with EMS. Yuanza 9102

2017 PLoS ONE

39. SPOT Vision Screening

Disorder (ASD), chromosomal abnormalities such as Down Syndrome, Cerebral Palsy (CP), and mental retardation (MR). Criteria Inclusion Criteria: child over 4 months of age social, behavioral, physical, or other handicap unable to complete age-appropriate vision screening Exclusion Criteria: glaucoma post intraocular surgery microphthalmia other serious eye disorder inability to complete SPOT screener Contacts and Locations Go to Information from the National Library of Medicine To learn more about (...) three SPOT screens around the time of their standard of care eye exam. The data obtained from the three SPOT screens will be compared among themselves for accuracy and to the findings of the clinical eye exam. Condition or disease Intervention/treatment Vision Disorders Diagnostic Test: Welch-Allyn Spot Vision Screener Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 100 participants Observational Model: Cohort Time Perspective: Prospective

2018 Clinical Trials

40. Mongolian Blue Spots Full Text available with Trip Pro

Mongolian Blue Spots 19986305 2010 06 24 2010 06 24 0035-9157 21 4 1928 Feb Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Mongolian Blue Spots. 571 Scott-Easton W H WH eng Journal Article England Proc R Soc Med 7505890 0035-9157 2009 12 9 6 0 1928 2 1 0 0 1928 2 1 0 1 ppublish 19986305 PMC2102073

1928 Proceedings of the Royal Society of Medicine

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